Profiling the Gut Microbiome of Hylobatidae and Cercopithecinae: Insights Into the Health of Primates in Captivity

IF 0.8 4区农林科学 Q3 VETERINARY SCIENCES

Journal of Medical Primatology Pub Date : 2025-02-24 DOI:10.1111/jmp.70008

Roberta Chaya Tawie Tingga, Abd Rahman Mohd-Ridwan, Azroie Denel, Badrul Munir Md-Zain

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引用次数: 0

Abstract

Background

A healthy gut microbiome is essential for digestion in primates, for developing the gut immune system, and for defense against pathogen invasion. Next-generation sequencing allows for determining the microbiome composition and enables the continuous monitoring of primate health.

Methods

To comprehensively analyze the gut microbiome diversity of three endangered primate species at Matang Wildlife Centre—Hylobates abbotti, Macaca fascicularis, and Macaca nemestrina, using high-throughput sequencing of the 16S rRNA gene.

Results

A total of 18 phyla, 84 families, 188 genera, and 46 species were successfully classified. H. abbotti exhibited the highest microbial diversity with a distinct microbiome profile from the Macaca species. The presence of Treponema (nonpallidum), Bifidobacterium, and Faecalibacterium prausnitzii is critical for gut health, promoting digestion and maintaining the microbial balance.

Conclusion

This study highlights the importance of monitoring microbial diversity in captive primates to better understand their health and facilitate the early detection of potential pathogens. This also offers insights into microbiome-based strategies for improving overall animal welfare.

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分析弓形虫科和弓形虫科的肠道微生物组：对圈养灵长类动物健康的见解

健康的肠道微生物群对灵长类动物的消化、肠道免疫系统的发育和防御病原体入侵至关重要。下一代测序允许确定微生物组组成，并使灵长类动物健康的持续监测。方法利用16S rRNA基因高通量测序技术，对马唐野生动物中心3种濒危灵长类动物——阿伯提猕猴（hylobates abbotti）、束斑猕猴（Macaca fascicularis）和nemestrina的肠道微生物多样性进行综合分析。结果成功分类18门84科188属46种。H. abbotti表现出最高的微生物多样性，与Macaca物种具有明显的微生物组特征。密螺旋体（非梅毒螺旋体）、双歧杆菌和prausnitzii粪杆菌的存在对肠道健康、促进消化和维持微生物平衡至关重要。结论本研究强调了监测圈养灵长类动物微生物多样性对更好地了解其健康状况和促进早期发现潜在病原体的重要性。这也为改善整体动物福利的基于微生物组的策略提供了见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Medical Primatology 生物-动物学

CiteScore

1.40

自引率

42.90%

发文量

审稿时长

6 months

期刊介绍： The Journal of Medical Primatology publishes research on non-human primates as models to study, prevent, and/or treat human diseases; subjects include veterinary medicine; morphology, physiology, reproductive biology, central nervous system, and cardiovascular diseases; husbandry, handling, experimental methodology, and management of non-human primate colonies and laboratories; non-human primate wildlife management; and behaviour and sociology as related to medical conditions and captive non-human primate needs. Published material includes: Original Manuscripts - research results; Case Reports - scientific documentation of a single clinical study; Short Papers - case histories, methodologies, and techniques of particular interest; Letters to the Editor - opinions, controversies and sporadic scientific observations; Perspectives – opinion piece about existing research on a particular topic; Minireviews – a concise review of existing literature; Book Reviews by invitation; Special Issues containing selected papers from specialized meetings; and Editorials and memoriams authored by the Editor-in-Chief.