{"title":"Acute Epididymo-Orchitis Caused by Escherichia coli in a Rhesus Monkey","authors":"Heling Li, Long Zhang, Hong Wang","doi":"10.1111/jmp.70004","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>Epididymo-orchitis is characterized by painful swelling and inflammation of the epididymis and testes. A 4-year-old male rhesus monkey has clinical manifestations including anorexia, weakness, as well as redness and swelling of the right testis and epididymis. Bacterial culture of the urine was positive for <i>Escherichia coli</i>. Due to the antibiotic treatment being ineffective, the animal underwent a right orchiectomy. Postoperative histopathology confirmed necrosis and significant inflammatory cell infiltration, indicating severe acute epididymo-orchitis (EO) caused by <i>E. coli</i> infection in the rhesus monkey. After surgical treatment and postoperative care, the animal survived. To our knowledge, this represents the first report of acute EO caused by <i>E. coli</i> in a rhesus monkey. These findings not only enhance our understanding of EO in NHPs but also provide a reference for further biomedical studies of EO induced by <i>E. coli.</i></p>\n </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"54 2","pages":""},"PeriodicalIF":0.8000,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Primatology","FirstCategoryId":"97","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/jmp.70004","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Epididymo-orchitis is characterized by painful swelling and inflammation of the epididymis and testes. A 4-year-old male rhesus monkey has clinical manifestations including anorexia, weakness, as well as redness and swelling of the right testis and epididymis. Bacterial culture of the urine was positive for Escherichia coli. Due to the antibiotic treatment being ineffective, the animal underwent a right orchiectomy. Postoperative histopathology confirmed necrosis and significant inflammatory cell infiltration, indicating severe acute epididymo-orchitis (EO) caused by E. coli infection in the rhesus monkey. After surgical treatment and postoperative care, the animal survived. To our knowledge, this represents the first report of acute EO caused by E. coli in a rhesus monkey. These findings not only enhance our understanding of EO in NHPs but also provide a reference for further biomedical studies of EO induced by E. coli.
期刊介绍：
The Journal of Medical Primatology publishes research on non-human primates as models to study, prevent, and/or treat human diseases; subjects include veterinary medicine; morphology, physiology, reproductive biology, central nervous system, and cardiovascular diseases; husbandry, handling, experimental methodology, and management of non-human primate colonies and laboratories; non-human primate wildlife management; and behaviour and sociology as related to medical conditions and captive non-human primate needs.
Published material includes: Original Manuscripts - research results; Case Reports - scientific documentation of a single clinical study; Short Papers - case histories, methodologies, and techniques of particular interest; Letters to the Editor - opinions, controversies and sporadic scientific observations; Perspectives – opinion piece about existing research on a particular topic; Minireviews – a concise review of existing literature; Book Reviews by invitation; Special Issues containing selected papers from specialized meetings; and Editorials and memoriams authored by the Editor-in-Chief.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
