Journal of Medical Primatology最新文献

{"title":"Oral Presentations","authors":"","doi":"10.1111/jmp.12673","DOIUrl":"https://doi.org/10.1111/jmp.12673","url":null,"abstract":"","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"52 5","pages":"298-343"},"PeriodicalIF":0.7,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50138142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of fine-needle aspiration techniques","authors":"Jason P. Dufour,&nbsp;Carolina Allers,&nbsp;Faith Schiro,&nbsp;Kathrine P. Falkenstein,&nbsp;Kayleigh K. Gregoire,&nbsp;Colin D. Glover,&nbsp;Alayna N. Chamel,&nbsp;Adrienne Woods,&nbsp;Jonah P. Phillippi,&nbsp;Taylor M. Gideon,&nbsp;Amitinder Kaur","doi":"10.1111/jmp.12676","DOIUrl":"10.1111/jmp.12676","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Fine-needle aspiration (FNA) has been reported since 1912 beginning with the use of trocars and other specialized instruments that were impractical. Since then, FNA has proven to be a successful alternative technique to excisional biopsy for some assays despite a few limitations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In this study, we compared four different techniques for FNA in rhesus macaques by evaluating total live cells recovered and cell viability using a standard 6 mL syringe and 1.5-inch 22-gauge needle.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Technique B which was the only technique in which the needle was removed from the syringe after collection of the sample to allow forced air through the needle to expel the contents into media followed by flushing of the syringe and needle resulted in the highest total cell count and second highest cell viability in recovered cells.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Based on our results, Technique B appears to be the superior method.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"52 6","pages":"400-404"},"PeriodicalIF":0.7,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jmp.12676","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10245603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hematology and blood biochemistry in a declining population of mantled howler monkeys (Alouatta palliata palliata) at La Pacifica, Costa Rica","authors":"Lisa C. Corewyn,&nbsp;Mary A. Kelaita,&nbsp;Jenny Nollman,&nbsp;Isabel Hagnauer,&nbsp;Kinndle Blanco-Peña,&nbsp;Robert G. Lessnau,&nbsp;Jonathan B. Clayton,&nbsp;Robin Shields-Cutler,&nbsp;Kari Brossard Stoos","doi":"10.1111/jmp.12669","DOIUrl":"10.1111/jmp.12669","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p><i>Alouatta palliata palliata</i> are an ecologically flexible howler monkey subspecies that has recently been relisted as Endangered. Populations are declining through much of the subspecies' range, including at our study site at La Pacifica, Costa Rica. Our objectives were to screen blood hematology and biochemistry samples collected from this wild population to elucidate their baseline health.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We collected blood samples from 38 adult individuals from across the study site and analyzed 13 hematology and 14 biochemistry parameters.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Most hematology and blood biochemistry parameter values were similar between males and females. However, mean hemoglobin was significantly lower, and mean white blood cell count was significantly higher in females; and mean calcium and mean creatinine were significantly lower in females compared to males.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Overall, the La Pacifica population appeared healthy based on the blood parameters analyzed from sampled individuals. Our results were also largely consistent with published data available from other populations of <i>A. p. palliata</i>, and with reference values for captive <i>Alouatta caraya</i>.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"52 6","pages":"353-360"},"PeriodicalIF":0.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10132563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Viral evolution of SIV chimpanzee toward HIV-1 using humanized mice","authors":"James Z. Curlin,&nbsp;Kimberly Schmitt,&nbsp;Leila Remling-Mulder,&nbsp;Corina Valencia Tibbitts,&nbsp;Shelby O'Connor,&nbsp;Preston Marx,&nbsp;Ramesh Akkina","doi":"10.1111/jmp.12675","DOIUrl":"10.1111/jmp.12675","url":null,"abstract":"<p>HIV-1 emerged from SIVcpz evolving in humans. Humanized mice are an effective tool for assessing viral evolution via measuring viral loads, CD4⁺ T cell decline, and analyzing genetic changes. Four serial passages showed many non-synonymous mutations important for the adaptation and evolution of SIVcpz to human immune cells.</p>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"52 5","pages":"294-297"},"PeriodicalIF":0.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jmp.12675","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10305370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterizing the phenotypic and genetic changes of pre-epidemic HIV-2 group F virus following serial passage in humanized mice","authors":"James Z. Curlin,&nbsp;Kimberly Schmitt,&nbsp;Leila Remling-Mulder,&nbsp;Corina Valencia Tibbitts,&nbsp;Shelby O'Connor,&nbsp;Preston Marx,&nbsp;Ramesh Akkina","doi":"10.1111/jmp.12674","DOIUrl":"10.1111/jmp.12674","url":null,"abstract":"<p>HIV-2 Group F virus with an origin in NHPs was isolated from only two individuals. Two serial passages in hu-mice showed increased viral loads, CD4⁺ T cell decline and nonsynonymous genetic changes showing its capacity for further evolution, and spread in the human.</p>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"52 5","pages":"290-293"},"PeriodicalIF":0.7,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jmp.12674","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10652354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First report of spontaneous hepatic fibrosarcoma in a white-tufted marmoset (Callithrix jacchus) kept in captivity","authors":"Soraya Kezam Malaga,&nbsp;Melina Castilho de Souza Balbueno,&nbsp;Jéssica Amâncio Martins,&nbsp;Leonardo Dourado da Costa,&nbsp;Maria Luiza de Sousa Barbosa,&nbsp;Cidéli de Paula Coelho","doi":"10.1111/jmp.12671","DOIUrl":"10.1111/jmp.12671","url":null,"abstract":"<p>Reports of sarcomas in nonhuman primates are scarce and, specifically, primary hepatic sarcomas are rare, as in humans. This is the first report of an aggressive hepatic fibrosarcoma in a young adult <i>Callithrix jacchus.</i> The final postmortem diagnosis was obtained by means of immunohistochemical analysis, which confirmed the tumor histogenesis.</p>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"53 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10110462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of hematology and clinical chemistry results in laboratory and zoo nonhuman primates: Effects of the preanalytical phase. A review","authors":"Fanny A. Granat,&nbsp;Catherine Trumel,&nbsp;Jean-Pierre D. Braun,&nbsp;Nathalie H. Bourgès-Abella","doi":"10.1111/jmp.12666","DOIUrl":"10.1111/jmp.12666","url":null,"abstract":"<p>Most errors in clinical pathology originate in the preanalytical phase, which includes all steps from the preparation of animals and equipment to the collection of the specimen and its management until analyzed. Blood is the most common specimen collected in nonhuman primates. Other specimens collected include urine, saliva, feces, and hair. The primary concern is the variability of blood hematology and biochemistry results due to sampling conditions with the effects of capture, restraint, and/or anesthesia. Housing and diet have fewer effects, with the exception of food restriction to reduce obesity. There has been less investigation regarding the impact of sampling conditions of nonblood specimens.</p>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"52 6","pages":"414-427"},"PeriodicalIF":0.7,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jmp.12666","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10060378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fatal Simplexvirus humanalpha1 infection in howler-monkeys (Alouatta sp.) under human care: Clinical, molecular, and pathological findings","authors":"Joanna V. Z. Echenique,&nbsp;Anderson H. Gris,&nbsp;Laura J. Camargo,&nbsp;Cíntia De Lorenzo,&nbsp;Marianna Bertolini,&nbsp;Franscisca M. S. Barbosa,&nbsp;Moira Ansolch,&nbsp;Cláudio W. Canal,&nbsp;Welden Panziera,&nbsp;Saulo P. Pavarini,&nbsp;Luciana Sonne","doi":"10.1111/jmp.12670","DOIUrl":"10.1111/jmp.12670","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p><i>Simplexvirus humanalpha1</i> (HuAHV-1) are common anthropozoonosis reported in marmosets but rare in howler monkeys (<i>Alouatta</i> sp.).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Necropsy of two brown-howler monkeys (<i>A. caraya</i>) and one red-howler monkey (<i>A. guariba clamitans</i>) from different zoo collections were performed. Fragments of all organs were examined through microscopy. Samples were submitted to IHC for <i>Simplexvirus humanalpha 2</i> (HuAHV-2) [sin. Herpesvirus simplex type 2] and PCR.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Grossly, only the <i>A. guariba</i> showed liver lesions characterized by multifocal, pinpoint white areas corresponding microscopically as random necrotizing herpetic hepatitis and ulcerative glossitis. Both <i>A. caraya</i> showed necrotizing meningoencephalitis with Cowdry A-type body inclusions within neurons and astrocytes. Immunolabeling for HuAHV-1/2 was observed in the tongue, liver, and brain. HuAHV-1 was confirmed in all samples by PCR, Sanger sequencing, and phylogenetic analyses.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Necrotizing meningoencephalitis was appreciated in 2/3 of animals, and it is associated with neurologic signs. Along with ulcerative glossitis, a hallmark lesion in marmosets, it was present in one animal. Regarding herpetic hepatitis, it is not frequent in monkeys and occurs mainly in immunocompromised animals. HuAHV-1 infection was confirmed corroborating with a human source. This is the second report on captive black-howler monkeys and the first gross, histologic, immunohistochemical, and molecular description of herpetic hepatitis and ulcerative glossitis in red-howler monkeys (<i>A. guariba</i>).</p>\u0000 </section>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"52 6","pages":"392-399"},"PeriodicalIF":0.7,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10032501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clostridium ventriculi in a cynomolgus monkey with acute gastric dilatation and rupture: A case report","authors":"Gyu-Seo Bae,&nbsp;Eun-Su Jeon,&nbsp;Hee Chang Son,&nbsp;Philyong Kang,&nbsp;Kyung Seob Lim,&nbsp;Eun-Ha Hwang,&nbsp;Green Kim,&nbsp;Seung Ho Baek,&nbsp;You Jung An,&nbsp;Gyu Young Shim,&nbsp;Young Min Woo,&nbsp;YuJin Kim,&nbsp;Taehwan Oh,&nbsp;Seok-Hwan Kim,&nbsp;JungJoo Hong,&nbsp;Bon-Sang Koo","doi":"10.1111/jmp.12668","DOIUrl":"10.1111/jmp.12668","url":null,"abstract":"<p>Acute gastric dilatation (AGD) is one of the most prevalent and life-threatening diseases in nonhuman primates worldwide. However, the etiology of this syndrome has not been determined. Recently, sudden death occurred in a 7-year-old female cynomolgus monkey with a history of fecal microbiota transplantation using diarrheic stools. The monkey had undergone surgery previously. On necropsy, gastric dilatation and rupture demonstrated a tetrad arrangement on histopathologic examination. On 16S rRNA sequencing, a high population of <i>Clostridium ventriculi</i> was identified in the duodenum adjacent to stomach but not in the colon. This paper is the first report of <i>Clostridium ventriculi</i> infection in a cynomolgus macaque with acute gastric dilatation and rupture.</p>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"53 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jmp.12668","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10359413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Housing relocation does not have to induce a significant stress response in captive Japanese macaques (Macaca fuscata)","authors":"Nelson Broche Jr.,&nbsp;Vanessa Gris,&nbsp;Naoko Suda-Hashimoto,&nbsp;Keiko Mouri,&nbsp;Takako Miyabe-Nishiwaki,&nbsp;Juri Suzuki,&nbsp;Michael A. Huffman","doi":"10.1111/jmp.12667","DOIUrl":"10.1111/jmp.12667","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Previous studies suggest that housing relocation may be stressful for captive non-human primates. Our study investigated the stress levels of Japanese macaques during a housing relocation by measuring their daily fecal cortisol metabolites, which are often used as an indicator of stress.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Ten adult Japanese macaques, single-housed for research purposes, were relocated to a new facility. Fecal samples were collected daily for 7 days. Cortisol metabolite concentrations were determined via enzyme immunoassay.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>No significant differences in cortisol metabolite levels were found in 7 days, but concentration levels showed that the highest median was associated to the relocation day.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The minimal cortisol metabolite increase suggests that there was a slight activity increase in the hypothalamic-pituitary-adrenal axis. Techniques encouraging cooperation of the monkeys, the short time duration of the relocation, and consistency in the environment may have contributed to the minimal stress levels observed.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16439,"journal":{"name":"Journal of Medical Primatology","volume":"52 6","pages":"347-352"},"PeriodicalIF":0.7,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10268971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}