Journal of investigative medicine high impact case reports最新文献_第4页

Facial Hyperpigmentation: A Rare Side Effect of Adalimumab. 面部色素沉着：阿达木单抗的罕见副作用

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241265896

Malek Mrad, Mariam Tabka, Asmahane Souissi, Ines Chelly, Mourad Mokni

引用次数: 0

A Late Recurrent Metastatic Breast Cancer Mimicking Primary Pancreatic Cancer: Case Report. 模仿原发性胰腺癌的晚期复发转移性乳腺癌：病例报告。

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241261511

Saida Sakhri, Ines Zemni, Safa Jouini, Fethia Abidi, Nadia Boujelbene, Tarek Ben Dhiab

{"title":"A Late Recurrent Metastatic Breast Cancer Mimicking Primary Pancreatic Cancer: Case Report.","authors":"Saida Sakhri, Ines Zemni, Safa Jouini, Fethia Abidi, Nadia Boujelbene, Tarek Ben Dhiab","doi":"10.1177/23247096241261511","DOIUrl":"10.1177/23247096241261511","url":null,"abstract":"Metastasis to the pancreas from malignant tumors is a rare event, representing only 1% to 2% of all pancreatic neoplasms. They occur in 2 different clinicopathological settings: as a manifestation in widespread metastatic disease or as an isolated mass in the pancreas. We report the case of a 41-year-old woman who had a history of invasive lobular breast cancer treated with radical surgery, chemotherapy, and radiotherapy. After 21 years of total remission, she presented for severe lower back pain with jaundice, nausea, and loss of 9 kg in 3 months. Abdominal computed tomography demonstrated a hyper vascularized, irregular solid lesion of 2.6 cm × 2.1 cm in the head of the pancreas with discreet biliary duct dilatation and coelio-mesenteric enlarged lymph nodes measuring 2 cm. The diagnosis of pancreatic metastasis from a lobular breast carcinoma was made by percutaneous biopsy of pancreatic lesion. The multidisciplinary committee decided a palliative treatment. The patient received chemotherapy. The take home message from his case is that we should keep in mind the hypothesis of a solitary metastasis to the pancreas, when the pancreatic lesion develops in a patient who had a clinical history of previous neoplasm especially in those which is known to potentially metastasize to pancreas.","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11185037/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141331092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Colorectal Carcinoma-An Anomalous Trigger of Adult Hemophagocytic Lymphohistiocytosis. 结直肠癌--成人嗜血细胞淋巴组织细胞增多症的异常诱因。

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241273131

Ameish Govindarajan, Frederick Venter, Akriti Chaudhry, Harsimranjit Kaur, Everardo Cobos, Greti Petersen

引用次数: 0

A Unique Presentation of Bacterial Group G Streptococcus Myopericarditis. 细菌性 G 群链球菌心肌炎的独特表现。

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241286363

Sacide S Ozgur, Nida Ansari, Alan Alcantara, Angela Pais Vidreiro, Ryan Rahman, Yezin Shamoon, Sherif Elkattawy, Rachel Abboud, Rajkumar Doshi, Fayez Shamoon

引用次数: 0

A Plasmacytoma of the Lateral Pharyngeal Wall: A Diagnostic Enigma. 咽侧壁浆细胞瘤：诊断之谜

IF 1.2

Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241242237

Lefika Bathobakae, Shayee Hasan, Aneeqa Shahid, Tyler Wilkinson, Shajla Ajas, Mehandar Kumar, Sohail Qayyum, Amer Akmal

{"title":"A Plasmacytoma of the Lateral Pharyngeal Wall: A Diagnostic Enigma.","authors":"Lefika Bathobakae, Shayee Hasan, Aneeqa Shahid, Tyler Wilkinson, Shajla Ajas, Mehandar Kumar, Sohail Qayyum, Amer Akmal","doi":"10.1177/23247096241242237","DOIUrl":"10.1177/23247096241242237","url":null,"abstract":"Plasmacytoma is a rare plasma cell dyscrasia that grows in bones or soft tissues such as the pharynx. Soft tissue plasmacytomas are rare, and a higher burden has been reported in the upper aero-digestive tract, often manifesting as hoarseness, dysphagia, or odynophagia. Due to their rarity, extramedullary plasmacytomas (EMPs) have unknown prognostic factors, and guidelines for optimal management are still lacking. However, radiation therapy and surgery have been used with positive outcomes. Herein, we describe a unique case of plasmacytoma of the pharyngeal tissue in a male patient with a history of HIV disease. The patient completed 28 sessions of radiation therapy, resulting in an improvement in his throat pain and hoarseness. Given the patient's age and lack of traditional risk factors for head and neck cancers, his hoarseness and odynophagia proved to be a diagnostic conundrum. Although infrequent, soft tissue plasmacytomas should be considered in the differential diagnosis of head and neck tumors.","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10996350/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140861540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Marginal Zone Lymphoma Manifesting as Macrophage Activation Syndrome: A Case Report. 表现为巨噬细胞活化综合征的边缘区淋巴瘤：病例报告

IF 1.2

Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241244732

Niloufar Ebrahimi, Sahibzadi Mahrukh Noor, Shahram Kordasti, Mojtaba Akhtari, Sayna Norouzi, Mehrbod Vakhshoori, Amir Abdipour

{"title":"Marginal Zone Lymphoma Manifesting as Macrophage Activation Syndrome: A Case Report.","authors":"Niloufar Ebrahimi, Sahibzadi Mahrukh Noor, Shahram Kordasti, Mojtaba Akhtari, Sayna Norouzi, Mehrbod Vakhshoori, Amir Abdipour","doi":"10.1177/23247096241244732","DOIUrl":"10.1177/23247096241244732","url":null,"abstract":"Macrophage activation syndrome (MAS) is a form of secondary hemophagocytic lymphohistiocytosis (HLH) when it occurs in the context of rheumatologic disorders. HLH is a rare and potentially life-threatening syndrome characterized by excessive immune system activation. It is mainly seen in children and can be genetic based or related to infections, malignancies, rheumatologic disorders, or immunodeficiency syndromes. MAS can present with nonspecific symptoms, leading to a delay in diagnosis. This report describes a case of a 64-year-old female with marginal zone lymphoma and systemic lupus erythematosus who presented with a purpuric rash and acute kidney injury. She underwent a kidney biopsy and was diagnosed with MAS. This case highlights the importance of promptly recognizing MAS's symptoms and signs, allowing timely diagnosis and early therapeutic intervention. This potentially fatal condition tends to respond well to rapid treatment initiation with corticosteroids and to address the underlying condition.","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10998482/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140851407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case Report of Pulmonary Vein Stenosis Within the Labyrinth of Fibrosing Mediastinitis. 纤维性纵隔炎迷宫内肺静脉狭窄病例报告

IF 1.2

Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241244729

Zakaria Alagha, Catherine Adams, Kylie Johnson, Amro Al-Astal

{"title":"A Case Report of Pulmonary Vein Stenosis Within the Labyrinth of Fibrosing Mediastinitis.","authors":"Zakaria Alagha, Catherine Adams, Kylie Johnson, Amro Al-Astal","doi":"10.1177/23247096241244729","DOIUrl":"10.1177/23247096241244729","url":null,"abstract":"This case centers on a 76-year-old male experiencing exertional dyspnea and hemoptysis, with a medical history marked by recurrent pulmonary embolism and chronic obstructive pulmonary disease (COPD). Notably, he resides in a histoplasmosis-endemic area. A computed tomography (CT) pulmonary embolism scan revealed notable findings, including an enlarged right lower pulmonary artery, vascular congestion, atelectasis, and a mass exerting pressure on the right lower pulmonary vein. Biopsy results identified the mass as fibrosing mediastinitis, likely attributed to histoplasmosis. A transthoracic echocardiogram indicated right ventricular dilatation, impaired function, and a right ventricular systolic pressure of 63 mm Hg. During right heart catheterization, the patient displayed disparate pulmonary artery wedge pressures (PAWPs) between the right and left sides. This discrepancy was linked to a blunted back wave from the left atrium to the catheter, induced by pulmonary vein compression. Although an infrequent phenomenon, the recorded asymmetry in PAWPs played a crucial role in guiding accurate patient management. The absence of subsequent evaluation of PAWP on the left side could have altered the treatment plan, potentially delaying appropriate patient care. This case emphasizes the necessity of thorough exploration with right heart catheterization when clinical symptoms warrant, highlighting the importance of standardized practices in such procedures.","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10996351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140870450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rare Case of Atrial Septal Mass Secondary to Lymphoma: Case Report and Review of Literature. 淋巴瘤继发心房隔膜肿块的罕见病例：病例报告与文献综述

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241273108

Amulya Prakash, Farhan Khalid, Haresh Gandhi, Dhyey Mungalpara

引用次数: 0

Streptococcal Esophagitis in an Immunocompetent Patient: A Rare Sequelae. 免疫力低下患者的链球菌性食管炎：罕见的后遗症

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241271985

Lefika Bathobakae, Nader Mekheal, Derya Mücahit, Mina Fransawy Alkomos, Alisa Farokhian, Yana Cavanagh, Walid Baddoura

引用次数: 0

Non-recurrent Laryngeal Nerve During Intraoperative Neuromonitoring Thyroidectomy: A Case Report and Literature Review. 术中神经监测甲状腺切除术中的非复发性喉神经：病例报告与文献综述

IF 0.9

Journal of investigative medicine high impact case reports Pub Date : 2024-01-01 DOI: 10.1177/23247096241273099

Davide Inversini, Simone Gianazza, Matteo Annoni, Andrea Leotta, Dorotea Confalonieri, Enrico Ferri, Andrea Palillo, Andrea Vigezzi, Sabrina Garbarino, Giuseppe Ietto, Giulio Carcano

{"title":"Non-recurrent Laryngeal Nerve During Intraoperative Neuromonitoring Thyroidectomy: A Case Report and Literature Review.","authors":"Davide Inversini, Simone Gianazza, Matteo Annoni, Andrea Leotta, Dorotea Confalonieri, Enrico Ferri, Andrea Palillo, Andrea Vigezzi, Sabrina Garbarino, Giuseppe Ietto, Giulio Carcano","doi":"10.1177/23247096241273099","DOIUrl":"10.1177/23247096241273099","url":null,"abstract":"Complete and precise knowledge of the neck anatomy and its eventual anomalies is crucial while performing a safe thyroid and parathyroid surgery. Embryo-genetic malformations of the IV branchial arch can lead to an uncommon anatomical alteration known as non-recurrent inferior laryngeal nerve. Its prevalence varies between 0.7% for the dextral branch and 0.04% for the sinistral. In these cases, the inferior laryngeal nerve branches originate directly from the cervical vagus nerve, entering the larynx without hooking, on the right side around the subclavian artery or on the left around the aortic arch. The presence of a non-recurrent laryngeal nerve is challenging, due to the increased risks of iatrogenic damage to the nerve, which results in hoarseness, dysphagia, glottal obstruction, vocal cords palsy, and serious airway impairment. We present the case of a 58-year-old woman. The patient was admitted to our department for a nodule classified as Bethesda IV in the right thyroid lobe. Through the use of intraoperative neuromonitoring (IONM), surgeons detected intraoperatively a non-recurrent laryngeal nerve. A subsequent computed tomography scan confirmed an anomalous right subclavian artery branching from the left aortic arch, the Lusoria Artery. Anatomical variants represent pitfalls in this case and an accurate knowledge of the neck region is imperative while performing thyroid surgery. Devices such as IONM are useful for detecting abnormalities that may lead to iatrogenic damages.","PeriodicalId":16198,"journal":{"name":"Journal of investigative medicine high impact case reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11366100/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0