Journal of Food Biochemistry最新文献

{"title":"Impact of Sowing Dates and Nitrogen Levels on the Phenolic Profile, Antioxidant, and Enzyme Inhibitory Activities of Ricinus communis L. Roots","authors":"Yunus Guzel,&nbsp;Sema Basbag,&nbsp;Abbas Tarhan,&nbsp;Ismail Yener","doi":"10.1155/jfbc/2264753","DOIUrl":"https://doi.org/10.1155/jfbc/2264753","url":null,"abstract":"<p>A wide range of biological effects, including antioxidant, antimicrobial, anti-inflammatory, and antiproliferative activities, have been attributed to phenolic compounds, a group of bioactive molecules naturally occurring in plant tissues and increasingly valued for their industrial relevance. Notably, the present study demonstrates that sowing date is a key determinant of phenolic content and associated biological activities. Comprehensive LC–MS/MS analysis revealed that gallic acid (20.66 mg/g extract), ellagic acid (15.78 mg/g extract), and quinic acid (11.12 mg/g extract) were the predominant phenolic constituents of the ethanol extracts obtained from the roots of <i>Ricinus communis</i> L. In addition, the extracts exhibited moderate antioxidant activity in DPPH, ABTS, and CUPRAC assays, with IC₅₀ values of 37.94 ± 0.58 and 9.26 ± 0.08 μg/mL and an <i>A</i>_0.5 value of 30.91 ± 0.56 μg/mL, respectively. Enzyme inhibition assays revealed moderate inhibitory activity against urease inhibition%: 51.17 ± 0.77, and <i>α</i>-amylase inhibition%: 14.39 ± 0.17, whereas strong inhibition was observed against <i>α</i>-glucosidase inhibition%: 98.23 ± 1.03. These findings indicate that <i>R. communis</i> root extracts represent a promising source of bioactive compounds with notable <i>α</i>-glucosidase inhibitory potential and supportive antioxidant activity.</p>","PeriodicalId":15802,"journal":{"name":"Journal of Food Biochemistry","volume":"2026 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/jfbc/2264753","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148095428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unravelling the Ameliorative Mechanisms of Ellagitannins From Pomegranate Peel on Fructose-Induced Detrimental Metabolic Alterations in Rats","authors":"Nomonde P. Mapasa,&nbsp;Tebalelo Lehlaleroa,&nbsp;Claudia M. Ntsapi,&nbsp;Tshepiso J. Makhafola,&nbsp;Samson S. Mashele,&nbsp;Chika I. Chukwuma","doi":"10.1155/jfbc/4066533","DOIUrl":"https://doi.org/10.1155/jfbc/4066533","url":null,"abstract":"<p>Pomegranate fruit is known to benefit oxidative and vascular health, which has been linked to some constituent ellagitannins. However, it remains unknown whether pomegranate ellagitannins can mitigate the detrimental metabolic alterations caused by added sugars like sucrose and fructose. Hence, this study investigated the ameliorative potential of pomegranate peel ellagitannins on fructose-induced metabolic alterations. An ellagitannin-rich fraction was recovered from the peel of pomegranate (Wonderful var.) using an Amberlite XAD16N resin. The fraction was subjected to LC–MS analysis. The fraction (200 mg/kg bw) was administered to Sprague–Dawley rats receiving 20% fructose solution in place of drinking water for 6 weeks. Food intake, body weight, blood glucose and blood lipids were measured. Thereafter, insulin level, glycogen content, oxidative stress and inflammatory markers, hepatic histology and HOMA-IR were determined. Hepatic Akt phosphorylation and phospho-PI3K expression were also determined. Fructose consumption suppressed food intake and increased weight gain. It further increased insulin levels and impaired glucose tolerance (AUC = 246 vs. 208 mg.h/dL) and insulin action (HOMA-IR = 5.8 vs. 2.0); altered blood lipid levels (triglycerides = 4.2 vs. 1.7 mmol/L; LDL-cholesterol = 3.0 vs. 1.4 mmol/L; HDL-cholesterol = 0.4 vs. 0.8 mmol/L); caused hepatic histological abnormalities and inflammation (IL-1β elevation) and increased hepatic and systemic oxidative stress. Ellagitannin treatment improved glucose tolerance (AUC = 230 mg.h/dL), insulin resistance (HOMA-IR = 4.0; improved hepatic Akt phosphorylation and phospho-PI3K expression), blood lipid profile (triglycerides, LDL-cholesterol and HDL-cholesterol = 3.7, 1.9 and 0.6 mmol/L, respectively), hepatic histology, inflammation and antioxidant status (reduced lipid peroxidation and increased SOD and catalase enzyme activity). LC–MS showed the presence of bioactive ellagitannins (punicalagin, corilagin and pendunculagin) and catechins. Ellagitannins from pomegranate peel mitigated against fructose-induced insulin resistance, dyslipidaemia, proinflammatory signalling and oxidative stress. Pomegranate peel ellagitannins may be useful dietary polyphenols to prevent or manage sugar-induced metabolic, cardiovascular and oxidative disorders.</p>","PeriodicalId":15802,"journal":{"name":"Journal of Food Biochemistry","volume":"2026 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/jfbc/4066533","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147686132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Assessment of the Therapeutic Effects of Ethanolic Extracts From Dragon Fruit and Mangosteen on Cadmium-Induced Hepatotoxicity in Rats","authors":"Lashin S. Ali,&nbsp;Hoda A. Fansa,&nbsp;Maha A. Aljumaa,&nbsp;Dalal S. Alshaya,&nbsp;Manal Almatrafi,&nbsp;Khalid M. Alsyaad,&nbsp;Ehab I. El-Hallous,&nbsp;Fawziah A. Al-Salmi,&nbsp;Tamer M. Shawky,&nbsp;Nermine Beshara,&nbsp;Mohamed G. Shalan,&nbsp;Eman Fayad,&nbsp;Mamdouh Eldesoqui,&nbsp;Dlovan Y. Khalil,&nbsp;Rozhan Yassin Khalil,&nbsp;Ibrahim Youssef,&nbsp;Shady G. El-Sawah","doi":"10.1155/jfbc/2327330","DOIUrl":"https://doi.org/10.1155/jfbc/2327330","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Because of its incredibly long half-life in the body, cadmium (Cd) is a powerful toxicant that poses a risk to the environment and workers. Even modest exposure levels to Cd can cause severe oxidative stress in the liver and other organs. Therefore, dietary components with established antioxidant activity may be used to avoid or even mitigate Cd intoxication.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In order to assess and compare the hepatoprotective effects of administering ethanolic extracts of dragon fruit (Df) and mangosteen (MGS) against Cd intoxication in rats, a 4-week study was designed. Seven groups of 70 male rats were created: normal control, ethanol vehicle control, MGS (300 mg/kg), Df (300 mg/kg), Cd-induced group (5 mg/kg), Cd + MGS, and Cd + Df groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Cd exposure markedly decreased serum albumin, globulins, and total proteins while increasing levels of lipid profile fractions (apart from HDL-C), liver function enzymes (ALT, AST, ALP, and γ-GT), and total bilirubin. Furthermore, despite levels of oxidative stress markers, including MDA, ROS, XO, and NO increased, Cd decreased the liver antioxidant contents of CAT, SOD, GSH, and GPX, in addition to diminishing hepatic immunity, as evidenced by the decreased CD4 and CD8 hepatic levels. Additionally, it was discovered that Cd reduced Bcl-2 and caused hepatic cell death, as indicated by increased BAX and caspase-3 levels, as well as hepatic inflammation, as indicated by increased TNF-α, TGF-β, and IL-6 levels. The histological analysis, which showed significant hepatic tissue damage after Cd poisoning, validated these results.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Cd-induced disruptions in estimated biochemical parameters and histological damage were improved in rats treated with either MGS or Df, with marked hepatic ameliorative and antiapoptotic superiority to the Df-treated group. Because of their anti-inflammatory, antiapoptotic, and antioxidant properties, both plant extracts may be recommended as therapeutic supplements to prevent the liver damage caused by Cd in rats. They are also significantly better at treating Df.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15802,"journal":{"name":"Journal of Food Biochemistry","volume":"2026 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/jfbc/2327330","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147686071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to “Dietary olive oil enhances the oral tolerance of the food allergen ovalbumin in mice by regulating intestinal microecological homeostasis”","authors":"","doi":"10.1155/jfbc/9831650","DOIUrl":"https://doi.org/10.1155/jfbc/9831650","url":null,"abstract":"<p>Y. Ma, J. Li, Y. Guo, et al., “Dietary olive oil enhances the oral tolerance of the food allergen ovalbumin in mice by regulating intestinal microecological homeostasis,” <i>Journal of Food Biochemistry</i> 46, no. 10 (2022). https://doi.org/10.1111/jfbc.14297.</p><p>In the article titled “Dietary olive oil enhances the oral tolerance of the food allergen ovalbumin in mice by regulating intestinal microecological homeostasis,” there was an error in Figure 3a. More specifically, the images showing the SEM image of the PBS group and the H&amp;E staining of the intestinal mucosal tissue of the Model group were incorrect. These errors were introduced during figure assembly and should be corrected as follows:</p><p>We apologize for these errors.</p>","PeriodicalId":15802,"journal":{"name":"Journal of Food Biochemistry","volume":"2026 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/jfbc/9831650","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147685967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional Link Between IRC7 Allelic Variation and Carbon-Sulfur-β-Lyase Activity in Brewing Saccharomyces cerevisiae Strains","authors":"C. Nasuti,&nbsp;V. Papiani Ceramelli,&nbsp;D. Tagliazucchi,&nbsp;A. Cattivelli,&nbsp;L. Solieri","doi":"10.1155/jfbc/7937512","DOIUrl":"https://doi.org/10.1155/jfbc/7937512","url":null,"abstract":"<p>The <i>IRC7</i> gene encodes a β-lyase enzyme critical for the release of volatile thiols during beer fermentation, contributing to aroma development in fermented beverages. In this study, 15 <i>Saccharomyces cerevisiae</i> ale brewing strains were analyzed to investigate <i>IRC7</i> allelic diversity and its functional implications. Using a nested PCR approach combined with sequencing, three genotypes were identified: <i>I</i><i>R</i><i>C</i>7^L/<i>I</i><i>R</i><i>C</i>7^L, <i>I</i><i>R</i><i>C</i>7^L <i>/</i> <i>I</i><i>R</i><i>C</i>7^S, and <i>I</i><i>R</i><i>C</i>7^S <i>/</i> <i>I</i><i>R</i><i>C</i>7^S. Allelic segregation in two sporulation-competent heterozygous strains was achieved through spore dissection and haplo-selfing, enabling the generation of homozygous monosporic derivatives. In total, 18 <i>IRC7</i> sequences were characterized, including 15 <i>I</i><i>R</i><i>C</i>7^L alleles carrying different combinations of 9 amino acid substitutions and 3 truncated <i>I</i><i>R</i><i>C</i>7^S variants. Two substitutions previously associated with reduced enzymatic activity, G101D and T185A, were frequently detected in <i>I</i><i>R</i><i>C</i>7^L alleles. Protein stability predictions indicated a destabilizing effect of these mutations, and sequence similarity analysis highlighted substantial variability among closely related <i>I</i><i>R</i><i>C</i>7^L variants. In vitro β-lyase activity assays performed using three model substrates (L-cysteine, S-ethyl-L-cysteine, and S-methyl-L-cysteine) showed that strains carrying <i>I</i><i>R</i><i>C</i>7^L generally exhibited higher enzymatic activity, while the presence of the <i>I</i><i>R</i><i>C</i>7^S allele or the T185A substitution in <i>I</i><i>R</i><i>C</i>7^L allele was associated with reduced activity in a substrate-dependent manner. Monosporic derivatives confirmed that the <i>I</i><i>R</i><i>C</i>7^S allele markedly impairs β-lyase activity and that T185A negatively affects activity toward S-methyl-L-cysteine. Overall, these findings expand the current knowledge of <i>IRC7</i> genetic and functional diversity in brewing strains and its implications for flavor development. The results provided a basis for implementing genotype-informed yeast selection, whereas the mating-competent monosporic derivatives carrying <i>I</i><i>R</i><i>C</i>7^L allele generated in this study represent valuable resources for future breeding strategies aimed at optimizing thiol release and aroma complexity in beer.</p>","PeriodicalId":15802,"journal":{"name":"Journal of Food Biochemistry","volume":"2026 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/jfbc/7937512","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147686899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular Docking Results Facilitate the Elucidation of Lipid Antioxidant Properties and SOD Activity of Resveratrol Butyrate Esters 3,4′-di-O-Butanoylresveratrol (ED2) and 3-O-Butanoylresveratrol (ED4)","authors":"Hua-Jin Fan,&nbsp;Yu-Wei Chen,&nbsp;Ping-Hsiu Huang,&nbsp;Chih-Yao Hou,&nbsp;Yi-Chung Liu,&nbsp;Shin-Yu Chen,&nbsp;Chang-Wei Hsieh,&nbsp;Ming-Kuei Shih","doi":"10.1155/jfbc/9274501","DOIUrl":"https://doi.org/10.1155/jfbc/9274501","url":null,"abstract":"<p>Resveratrol butyrate esters (RBEs) are novel derivatives synthesized through the esterification of resveratrol (RSV) and butyric acid. Among these, 3,4′-di-O-butanoylresveratrol (ED2) and 3-O-butanoylresveratrol (ED4) have been identified as abundant compounds with proven efficacy in inhibiting H₂O₂-induced cellular antioxidant damage. This study investigated the impact of ED2 and ED4 on the antioxidant properties of lipids, the activities of antioxidant enzymes, and their structural disparities. This study showed that ED2 and ED4 were preferred over RSV in preventing the oxidative performances of corn oil, β-carotene, and low-density lipoprotein (LDL). In addition, superoxide dismutase (SOD) activity was dose-dependent, and ED4 was superior to ED2. Molecular docking analysis of RSV, ED2, and ED4 in simulated SOD revealed that within the active region of SOD, ED2 displayed greater hydrophobic interactions with Asp11 and Cys55 amino acids compared to ED4. Moreover, the molecular docking analysis reveals that ED4 exhibits superior stability and antioxidant activity compared to ED2, elucidating this bonding phenomenon’s rationale. Notably, the butyrate esterification modification of RSV does not compromise the antioxidant activity. The findings of this study suggest that the presence of the retained 4′-OH group in ED4 may confer potential antioxidant properties, thereby indicating its possible application as a functional food ingredient or supplement.</p>","PeriodicalId":15802,"journal":{"name":"Journal of Food Biochemistry","volume":"2026 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/jfbc/9274501","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147686078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional Food Rich in Bioactive Components for Management of Obesity and Related Metabolic Changes in Obese Women","authors":"Sahar Y. Al-Okbi,&nbsp;Shaimaa E. Mohammed,&nbsp;Enas S. K. Al-Siedy,&nbsp;Said I. Shalaby,&nbsp;Doha A. Mohamed","doi":"10.1155/jfbc/2198770","DOIUrl":"https://doi.org/10.1155/jfbc/2198770","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Obesity is a global health problem that requires a safe and efficient approach. The objective of the research was to study how to manage obesity with functional food and dietary advice. Female obese subjects were given a daily amount of functional food for 2 months along with dietary advice. The functional food consisted of a mixture of powdered orange pectin, carrot, eggplant, oat, wheat bran, green tea, green coffee bean, <i>Nigella sativa</i> seeds, flax seed, roasted lemon, cumin seeds, fennel seeds, turmeric, ginger, cinnamon, and chili pepper. Anthropometric and biochemical parameters were assessed before and after dietary intervention. Bioactive components in the functional food were analyzed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Results showed obese subjects to demonstrate dyslipidemia and elevated insulin resistance, plasma malondialdehyde, glucose, and interleukin-6, together with reduced liver and kidney function compared to normal controls. Intervention with functional food with dietary advice produced significant improvement in the determined biochemical parameters except for triglycerides, high-density lipoprotein-cholesterol, nitric oxide, and alanine transaminase, which only showed insignificant improvements. The functional food also demonstrated a significant reduction in body mass index and waist/hip ratio. Analysis of the functional food showed high phenolic and flavonoid contents and phytosterols with an ω-3/ω-6 ratio of 1/10. Dietary fibers were calculated to be 30.94%.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The intervention with functional food together with dietary advice has antiobesity effect with potential reduction of comorbidities associated with obesity, which might be due to the presence of phenolic compounds, phytosterols, ω-3 fatty acids, and dietary fibers.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15802,"journal":{"name":"Journal of Food Biochemistry","volume":"2026 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/jfbc/2198770","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147686818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ailanthus altissima Extract Ameliorates Cognitive Decline and Neurodegeneration in an Aluminum Chloride–Induced Rat Model of Alzheimer’s Disease","authors":"Mohammad Mehdi Gravandi,&nbsp;Daniel Elieh-Ali-Komi,&nbsp;Roshanak Amirian,&nbsp;Seyede Zahra Hosseini,&nbsp;Seyede Darya Alavi,&nbsp;Samira Shirooie,&nbsp;Amir Kiani,&nbsp;Mohammad Hosein Farzaei","doi":"10.1155/jfbc/7471140","DOIUrl":"https://doi.org/10.1155/jfbc/7471140","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The extract of <i>Ailanthus altissima</i> possesses anti-inflammatory and neuroprotective properties. We aimed to investigate its effectiveness in mitigating the AlCl₃-induced Alzheimer’s disease in a rat model.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A total of 32 adult male Wistar rats were divided into 4 groups each consisting of 8 rats. The control group received saline and the AlCl₃ group received AlCl₃ (0.2 cc 100 mg/kg, intraperitoneal) for 14 days. Two other groups received either 50 or 100 mg/kg of <i>Ailanthus altissima</i> after AlCl₃ treatment. Behavioral tests including open field test (OFT), elevated plus maze, and passive avoidance tests were performed. Nuclear factor kappa B (NF-κB), glial filamentous acidic protein (GFAP), and amyloid beta were stained using immunohistochemistry (IHC) in the hippocampus.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>AlCl₃ administration caused significant memory impairment, and treatment with <i>Ailanthus altissima</i> extract effectively mitigated these deficits in a dose-dependent manner. The effects were dose-dependent, and the group receiving 100 mg/kg extract presented the most significant results in the conducted behavioral tests. The IHC results for NF-κB showed that treatment with 50 mg/kg of extract significantly reduced NF-κB expression compared with the AlCl₃ group (6.64% vs. 13.3%, respectively, <i>p</i> &lt; 0.05). A higher dose of 100 mg/kg resulted in an even greater reduction (4.45% vs. 13.3%, <i>p</i> &lt; 0.01). Extract treatment reduced GFAP positivity in a dose-dependent manner, with the 50 mg/kg group showing a significant decrease to 11.8% (<i>p</i> &lt; 0.05). The 100 mg/kg group demonstrated an even more substantial reduction to 7.7% (<i>p</i> &lt; 0.01) compared with the AlCl₃ group (18.65%). Amyloid beta positivity was critically reduced in the 100 mg/kg-receiving group.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p><i>Ailanthus altissima</i> extract shows potential as a neuroprotective extract. It counteracts AlCl₃-induced behavioral and neuropathological changes, suggesting promising therapeutic applications.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15802,"journal":{"name":"Journal of Food Biochemistry","volume":"2026 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/jfbc/7471140","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147686830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficient Extraction of Biologically Active and Technofunctional Sulfated Polysaccharides From Green Seaweed Ulva rigida Using Enzyme-Assisted Method","authors":"Samira Jeddi,&nbsp;Mehdi Alboofetileh,&nbsp;Sivakumar Priyadharshini,&nbsp;Hannah R. Vasanthi","doi":"10.1155/jfbc/3453161","DOIUrl":"https://doi.org/10.1155/jfbc/3453161","url":null,"abstract":"<p>The current study employed the enzyme-assisted extraction for the bioconversion of <i>Ulva rigida</i> and isolating the ulvan polysaccharide. The extracted ulvan was characterized using Fourier transform infrared spectroscopy, x-ray diffraction, electrospray ionization-mass spectrometry, and differential scanning calorimetry analysis. The antioxidant activity (scavenging of DPPH free radical and reducing power assays), antibacterial activity (against four food pathogenic bacteria), prebiotic activity, water- and oil-holding capacities, and emulsifying and foaming properties of the isolated ulvan were investigated. The ulvan yield from <i>U. rigida</i> by the enzyme method was 37.8%. The extracted ulvan possesses 92.64% DPPH scavenging and 0.2515 Abs, reducing power activities at a concentration of 4 mg/mL. Antibacterial studies revealed that the isolated ulvan exerted antibacterial activity against <i>Escherichia coli</i> and <i>Listeria monocytogenes</i> with 5- and 4-mm semidiameter inhibition zones at 10 mg/mL concentrations, respectively. However, it was not active against <i>Staphylococcus aureus</i> and <i>Salmonella enterica</i>. The growth of <i>Bifidobacterium bifidum</i>, <i>Lactobacillus acidophilus</i>, and <i>Lactobacillus plantarum</i> bacteria was increased in the presence of the extracted ulvan, which indicates its prebiotic activity. The water-holding capacity of the extracted ulvan (6.18 g water/g sample) was higher than its oil-holding capacity (0.5 g oil/g sample). The results also demonstrated that the extracted ulvan could emulsify the corn, sunflower, and canola oils. The foaming capacity and stability of the extracted ulvan were 14.08% and 4.30%, respectively. These results suggested that the enzyme method recovered ulvan from <i>U. rigida</i> with different bioactivities and technofunctional properties, making it suitable for application in various food and cosmetic products as a nutraceutical and natural preservative.</p>","PeriodicalId":15802,"journal":{"name":"Journal of Food Biochemistry","volume":"2026 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/jfbc/3453161","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147686739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to “Effects of Different Forms of Anthocyanins on the Growth Inhibition and Gene Expression of Colorectal Cancer Cells”","authors":"","doi":"10.1155/jfbc/9898372","DOIUrl":"https://doi.org/10.1155/jfbc/9898372","url":null,"abstract":"<p>W. Liu, S. Feng, D. He, et al., “Effects of Different Forms of Anthocyanins on the Growth Inhibition and Gene Expression of Colorectal Cancer Cells,” <i>Journal of Food Biochemistry</i>, 2024, 7191862, https://doi.org/10.1155/jfbc/7191862.</p><p>The conflicts of interest statement has also been corrected as below due to this change:</p><p>“Shuqiang Ren <i>was employed by AgSino Digital Nutrition Technology. The company provided no direct funding for this research and had no role in the study design, data collection, analysis, interpretation, or decision to publish. There are no other potential conflicts of interest related to this work</i>.”</p><p>We apologize for these errors.</p>","PeriodicalId":15802,"journal":{"name":"Journal of Food Biochemistry","volume":"2026 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/jfbc/9898372","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147687022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}