Journal of Burn Care & Research最新文献

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Understanding Epidemiological Trends in Geriatric Burn Injuries: A National Multicenter Analysis from NEISS 2004-2022. 了解老年烧伤的流行病学趋势:2004-2022年NEISS全国多中心分析。
IF 1.5 4区 医学
Journal of Burn Care & Research Pub Date : 2025-03-04 DOI: 10.1093/jbcr/irae102
Sam Boroumand, Beatrice Katsnelson, Alna Dony, Viola A Stögner, Lioba Huelsboemer, Neil Parikh, SeungJu Jackie Oh, Martin Kauke-Navarro, Alisa Savetamal, Bohdan Pomahac
{"title":"Understanding Epidemiological Trends in Geriatric Burn Injuries: A National Multicenter Analysis from NEISS 2004-2022.","authors":"Sam Boroumand, Beatrice Katsnelson, Alna Dony, Viola A Stögner, Lioba Huelsboemer, Neil Parikh, SeungJu Jackie Oh, Martin Kauke-Navarro, Alisa Savetamal, Bohdan Pomahac","doi":"10.1093/jbcr/irae102","DOIUrl":"10.1093/jbcr/irae102","url":null,"abstract":"<p><p>Burn injuries pose a significant source of patient morbidity/mortality and reconstructive challenges for burn surgeons, especially in vulnerable populations such as geriatric patients. Our study aims to provide new insights into burn epidemiology by analyzing the largest national, multicenter sample of geriatric patients to date. Using the National Electronic Injury and Surveillance System (NEISS) database (2004-2022), individuals with a \"burn\" diagnosis were extracted and divided into 2 comparison age groups of 18-64 and 65+. Variables including sex, race, affected body part, incident location, burn etiology, and clinical outcomes were assessed between the 2 groups using 2 proportion z-tests. About 60,581 adult patients who sustained burns were identified from the NEISS database with 6630 of those patients categorized as geriatric (65+). Geriatric patients had a significantly greater frequency of scald burns (36.9% vs 35.4%; P < .01), and third-degree/full-thickness burns (10.4% vs 5.5%, P < .01) relative to nongeriatric adult patients with most of these burns occurring at home (75.9% vs 67.4%; P < .01). The top 5 burn sites for geriatric patients were the hand, face, foot, lower arm, and lower leg and the top 5 burn injury sources were hot water, cookware, oven/ranges, home fires, and gasoline. Geriatric patients had over 2 times greater risk of hospital admission (odds ratio [OR]: 2.32, 95% CI: 2.17-2.49, P < .01) and over 5 times greater risk of emergency department mortality (OR: 6.22, 95% CI: 4.00-9.66, P < .01) after incurring burn injuries. These results highlight the need for stronger awareness of preventative measures for geriatric burn injuries.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"276-284"},"PeriodicalIF":1.5,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141261945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Individual Cognitive Stimulation Therapy on Caregivers of Burn Patients. 个人认知刺激疗法对烧伤患者护理人员的影响。
IF 1.5 4区 医学
Journal of Burn Care & Research Pub Date : 2025-03-04 DOI: 10.1093/jbcr/irae197
Cuina Zhang, Beibei Qin, Guihua Zhang, Jianke Feng, Wei Wei, Haitao Li, Liang Xing
{"title":"The Impact of Individual Cognitive Stimulation Therapy on Caregivers of Burn Patients.","authors":"Cuina Zhang, Beibei Qin, Guihua Zhang, Jianke Feng, Wei Wei, Haitao Li, Liang Xing","doi":"10.1093/jbcr/irae197","DOIUrl":"10.1093/jbcr/irae197","url":null,"abstract":"<p><p>This study aimed to investigate the effects of Individual Cognitive Stimulation Therapy (ICST) on the cognition, quality of life, and family relationships of caregivers of burn patients. A total of 98 caregivers of burn patients were randomly divided into a control group and a study group. The control group received routine interventions, while the study group underwent ICST, focusing on psychological diagnosis, comprehension, communication, and reeducation phases. Burn awareness levels, quality of life, social support utilization, and psychological resilience were assessed before and after the intervention. Before intervention, there were no significant differences in burn awareness levels, quality of life, social support utilization, or psychological resilience between the 2 groups. After the intervention, caregivers in the study group exhibited significantly higher scores in burn awareness levels, quality of life dimensions, social support utilization, and psychological resilience compared to the control group (P < .05). Individual cognitive stimulation therapy can improve the burn awareness level, quality of life, and social support utilization of caregivers of burn patients, highlighting its significant clinical implications in enhancing caregiver well-being and patient care.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"475-480"},"PeriodicalIF":1.5,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term Physical and Mental Health Outcomes of Older Adults Following a Major Burn Injury: A Burn Model System Investigation. 重大烧伤后老年人的长期身心健康结果:烧伤模型系统调查
IF 1.5 4区 医学
Journal of Burn Care & Research Pub Date : 2025-03-04 DOI: 10.1093/jbcr/irae187
Aaron Hong, Barclay T Stewart, Caitlin Orton, Gretchen J Carrougher, Jeffrey C Schneider, Kyra Solis-Beach, Alyssa Bamer, Karen Kowalske, Samuel Mandell
{"title":"Long-term Physical and Mental Health Outcomes of Older Adults Following a Major Burn Injury: A Burn Model System Investigation.","authors":"Aaron Hong, Barclay T Stewart, Caitlin Orton, Gretchen J Carrougher, Jeffrey C Schneider, Kyra Solis-Beach, Alyssa Bamer, Karen Kowalske, Samuel Mandell","doi":"10.1093/jbcr/irae187","DOIUrl":"10.1093/jbcr/irae187","url":null,"abstract":"<p><p>Older adults are at a higher risk of complications after burn injuries since many physical and mental changes are compounded by increasing age. Few studies have targeted the long-term effects of burns on older adults. Therefore, this study will investigate the long-term physical and mental health outcomes in older adults. About 3129 participants from the Burn Model System Database were divided into 3 cohorts based on their age at injury (18-54, 55-64, and 65+). Physical Component Summary (PCS) and Mental Component Summary (MCS) scores were derived from the 12-item Short Form (SF-12) and the Veterans RAND 12-item (VR-12) health surveys and analyzed to measure recovery at preinjury, discharge, 2-year follow-up, and 5-year follow-up. ANOVA, T-score analysis, and linear mixed-effects models were utilized to assess for significant differences in outcome scores. PCS scores were significantly different between the 18-54 cohort and 65+ cohorts at the preinjury and 2-year time intervals (P < .001 and P < .001, respectively) but not at the 5-year follow-up (P = .28). MCS scores were significantly different between the 18-54 cohort and 65+ cohorts at all time intervals measured (P = .001, P < .001, P < .001, and P = .005, respectively), though the change in MCS scores over time was not significantly different between age cohorts across time (P = .088). This supports that patients 65 years and older have a different physical function recovery trajectory when compared to patients under 64 years. These findings underscore the belief that for physical recovery after a burn injury, individualized physical rehabilitation plans will provide the most benefit for patients across all ages.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"450-458"},"PeriodicalIF":1.5,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142466337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of YouTube as a Health Education Resource for Skin Graft Procedures. 评估将 YouTube 作为皮肤移植手术健康教育资源的效果。
IF 1.5 4区 医学
Journal of Burn Care & Research Pub Date : 2025-03-04 DOI: 10.1093/jbcr/irae161
Grant B Torres, Kimberley C Brondeel, Trey R Sledge, Bradley M Nus, Sai A Kamma, Kylie Wu, Ludwik K Branski
{"title":"Evaluation of YouTube as a Health Education Resource for Skin Graft Procedures.","authors":"Grant B Torres, Kimberley C Brondeel, Trey R Sledge, Bradley M Nus, Sai A Kamma, Kylie Wu, Ludwik K Branski","doi":"10.1093/jbcr/irae161","DOIUrl":"10.1093/jbcr/irae161","url":null,"abstract":"<p><p>Recent studies indicate that YouTube has become a primary source of healthcare information for patients. Videos about Skin Graft Procedures (SGP) on YouTube have accumulated millions of views, yet there lacks a publication investigating the educational quality of this content. With current literature revealing misleading healthcare information found on YouTube, this study aims to evaluate the educational quality of videos related to SGP. YouTube was searched for various terms such as \"Skin Graft Procedures\" and \"Skin Graft Surgery.\" One hundred and five videos were assessed, with 21 excluded. Four independent reviewers rated the material with the Global Quality Scale (GQS) (5 = highest quality, 1 = lowest quality) to judge educational value. Viewership, source, modality, and date of upload were also collected from each video and compiled for further analysis. The average GQS was 2.60 amongst all videos, with videos led by physicians recording significantly higher scores than those not led by physicians (P < .01). In comparing educational modalities, physician-led presentations provided the highest educational value, whereas live surgeries and consumer-friendly content contained low educational quality (P < .01). Assessing videos split into cohorts based on viewership noted a significantly higher GQS in videos with lower view counts (P < .05). Skin graft videos on YouTube largely provide low-quality information. Videos performed by physicians, particularly physician-led presentations, significantly improved the educational quality of skin graft content. Physicians must involve themselves in enhancing the quality of online content to better guide patients in navigating treatment options and making healthcare decisions.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"361-366"},"PeriodicalIF":1.5,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety of Silver Dressings in Infants; a Systematic Scoping Review. 婴儿使用银敷料的安全性;系统性范围界定审查。
IF 1.5 4区 医学
Journal of Burn Care & Research Pub Date : 2025-03-04 DOI: 10.1093/jbcr/irae159
Patrick K O'Donohoe, Ryan Leon, David J A Orr, Catherine de Blacam
{"title":"Safety of Silver Dressings in Infants; a Systematic Scoping Review.","authors":"Patrick K O'Donohoe, Ryan Leon, David J A Orr, Catherine de Blacam","doi":"10.1093/jbcr/irae159","DOIUrl":"10.1093/jbcr/irae159","url":null,"abstract":"<p><p>Silver-based dressings are used to reduce infection risk and optimize conditions for wound healing. They are widely used in the management of burns and other complex wounds. However, reports of elevated serum silver and concern over systemic toxicity have meant that their use in young children has been questioned. The aim of the current study was to map the literature relating to the use of silver-based dressings in children under 1 year of age. A systematic scoping review was conducted according to the methodology described by the Joanna Briggs Institute. Sources were identified from major medical databases as well as the gray literature. Inclusion criteria were the use of silver-based dressing in children under 1 year of age. Outcomes of interest were complications or adverse events attributed to silver-based dressings and elevated serum silver levels. A total of 599 sources were identified through the search strategy, with 110 included for review. Complications were described in 31 sources, with the most frequent being wound infection. No cases of argyria, kernicterus, or methemoglobinemia were reported. Six sources documented elevated serum silver levels in infants but none reported adverse events related to this. On the basis of current evidence, we suggest reserving silver dressings in infants under 1 for wounds that are at high risk of infection. Wound area and duration of treatment should be considered when assessing the risk of systemic absorption of silver. Standardized data collection and recording of complications and adverse events is recommended to better inform future clinical decision-making.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"349-360"},"PeriodicalIF":1.5,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142008800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genital Burns Are Associated With Worse Psychosocial and Physical Outcomes. 生殖器烧伤与较差的社会心理和生理结果有关。
IF 1.5 4区 医学
Journal of Burn Care & Research Pub Date : 2025-03-04 DOI: 10.1093/jbcr/irae138
Suhaib Shah, George Golovko, Abbas Karim, Carolina Segura, Juquan Song, Maria Haseem, Steven Wolf, Amina El Ayadi
{"title":"Genital Burns Are Associated With Worse Psychosocial and Physical Outcomes.","authors":"Suhaib Shah, George Golovko, Abbas Karim, Carolina Segura, Juquan Song, Maria Haseem, Steven Wolf, Amina El Ayadi","doi":"10.1093/jbcr/irae138","DOIUrl":"10.1093/jbcr/irae138","url":null,"abstract":"<p><p>Genital burns are unique and complex injuries that impact patients physically and emotionally. This study investigates the specific impact of genital burns on psychosocial and physical outcomes. A retrospective cohort study was conducted using the TriNetX database, encompassing over 117 million patients from U.S. healthcare institutions. Patients with genital burns were identified and categorized into subcohorts based on total body surface area (TBSA) and burn degree. Propensity score matching and cohort balancing were performed based on age, gender, race, and ethnicity. Outcomes were analyzed both short-term (1 month) and long-term (5 years), focusing on psychiatric and physical aspects. This study identified 3496 genital burn patients over a 15-year period. Analyses revealed that genital burns significantly increased short-term risk of death (risk ratios [RR]: 2.8), anxiety (RR: 2.656), hospitalization (RR: 2.167), and any anxiety, posttraumatic stress disorder, or depression (RR: 2.363), and long-term risk of death (RR: 1.658) and pruritus (RR: 1.58) (all P < .05). Interestingly, genital burn patients showed a lower risk of chronic joint pain compared to other burn injuries (RR: 0.815) (P < .05). These results occurred independently of the extent of TBSA. Genital burns have a distinctive impact on patients, leading to higher rates of certain psychiatric morbidities and physical complications. This study highlights the need for tailored care and consideration of the unique challenges faced by patients with genital burns, both in the immediate aftermath and in the long term. Understanding the specific impacts of genital burns is vital for healthcare practitioners to develop care strategies and better support for patients recovering from such injuries.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"257-270"},"PeriodicalIF":1.5,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11879725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141563473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Individual-Level and Community-Level Social Determinants of Burn Injuries: A Single-Institution Study From the Southwestern United States. 烧伤的个人层面和社区层面的社会决定因素:美国西南部单一机构研究》。
IF 1.5 4区 医学
Journal of Burn Care & Research Pub Date : 2025-03-04 DOI: 10.1093/jbcr/irae131
Samuel Cohler, Henry Krasner, Kavita Batra, Syed Saquib
{"title":"The Individual-Level and Community-Level Social Determinants of Burn Injuries: A Single-Institution Study From the Southwestern United States.","authors":"Samuel Cohler, Henry Krasner, Kavita Batra, Syed Saquib","doi":"10.1093/jbcr/irae131","DOIUrl":"10.1093/jbcr/irae131","url":null,"abstract":"<p><p>Burn injuries are a significant public health concern, causing life-threatening complications and substantial hospitalization costs for patients. It has been shown that burn injuries may affect individuals differently based on demographic factors and socioeconomic status, among other variables. In the Southwestern United States with high ambient temperatures, specific burn etiologies, such as pavement burns, may pose a disproportionately high risk for disadvantaged communities and homeless individuals. This study uniquely explores burn injuries in relation to patients' socioeconomic status in Las Vegas, Nevada by using the Distressed Community Index to quantify socioeconomic status utilizing individual-level and community-level indicators. This single-institution and retrospective study collected data from all patients admitted to a burn center located in Las Vegas. Data were analyzed through Chi-square, one-way ANOVA, and post-hoc analysis with Tukey's test. Patients residing in distressed communities contributed to the greatest number of burn injuries; however, there was a lack of significant association between socioeconomic status and burn injury (P = 202). Additionally, specific burn etiologies and demographic characteristics were associated with variations in burn patient hospital course, complications, resources utilized and outcomes. Distressed patients were significantly associated with public insurance (P < 0.001), and public insurance users were associated with pavement burns-one of the most severe burn injuries (P < 0.001). This study emphasizes the importance of developing comprehensive burn prevention resources tailored to vulnerable populations, especially in regions with increased incidence of severe burn injuries, in order to reduce burn burden and mortality.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"307-317"},"PeriodicalIF":1.5,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11879727/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141544900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Single and Unhoused Population at Risk for Self-Inflicted Burn Injury: A Retrospective Analysis of an Urban American Burn Center's Experience. 有自我烧伤风险的单身和无住房人群:对美国城市烧伤中心经验的回顾性分析。
IF 1.5 4区 医学
Journal of Burn Care & Research Pub Date : 2025-03-04 DOI: 10.1093/jbcr/irae168
Artur Manasyan, Nicolas Malkoff, Brigette Cannata, Eloise W Stanton, Haig A Yenikomshian, T Justin Gillenwater, Sarah A Stoycos
{"title":"Single and Unhoused Population at Risk for Self-Inflicted Burn Injury: A Retrospective Analysis of an Urban American Burn Center's Experience.","authors":"Artur Manasyan, Nicolas Malkoff, Brigette Cannata, Eloise W Stanton, Haig A Yenikomshian, T Justin Gillenwater, Sarah A Stoycos","doi":"10.1093/jbcr/irae168","DOIUrl":"10.1093/jbcr/irae168","url":null,"abstract":"<p><p>Despite the growing recognition of self-harm as a pressing public health issue, demographic risk factors of self-inflicted burn (SIB) injuries in the United States have not been extensively described. In this retrospective study, we seek to identify demographic risk factors and patterns associated with SIB injuries at an urban burn center. Charts were reviewed of patients admitted to a single American Burn Association-verified burn unit between 2015 and 2023 with a history of SIB injury, identified with ICD10 code X76.XXXA. Descriptive statistics, Welch's t-test of unequal variances, and chi-squared analysis were performed. A total of 3212 patients were admitted to our institution for the management of acute burn injury, with 94 (2.9%) patients presenting with SIB injury. SIB patients were more likely than the control cohort to be male (P = .035), single (P = .008), unhoused (P < .001), live alone (P < 0.001), and have documented psychiatric diagnoses (72.3% vs 2.1%, P < .001). They had larger %TBSA affected (P < .001) and higher rates of inhalation injury (P < .001). The SIB cohort also showed significantly higher rates of positive urine toxicology results, primarily for stimulants and opiates (P < .001). Patients with SIBs had longer hospital stays (21.7 ± 2.6 days vs 12.0 ± 22.1 days, P = .006), higher rates of ICU admission (P < .001), and mechanical ventilation requirement (P < .001). Mental health support services, substance abuse rehabilitation programs, and community outreach need to be prioritized, especially targeting vulnerable populations such as the unhoused.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"386-392"},"PeriodicalIF":1.5,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142107802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gel Fuel Burns and the Napalm Effect. 凝胶燃料燃烧和汽油弹效应。
IF 1.5 4区 医学
Journal of Burn Care & Research Pub Date : 2025-03-04 DOI: 10.1093/jbcr/irae122
Muhammed Salih Süer, Ömer Cennet
{"title":"Gel Fuel Burns and the Napalm Effect.","authors":"Muhammed Salih Süer, Ömer Cennet","doi":"10.1093/jbcr/irae122","DOIUrl":"10.1093/jbcr/irae122","url":null,"abstract":"<p><p>Gel fuels, composed of flammable substances like ethanol and methanol, are commonly used for heating in various settings. Despite their convenience, improper handling can lead to severe burn injuries. This study examines the characteristics of gel fuels, particularly focusing on the \"napalm effect\" where the fuel continues to burn on surfaces it adheres to. A review of gel fuel burn literature was conducted, along with an analysis of 2 recent cases admitted to a burn unit. Gel fuel burns, though rare, can result in deep and extensive injuries, especially affecting the hands, face, and upper body. The cases presented highlight the severity of such burns and the challenges in their management, including respiratory complications and the need for early excision and grafting. Gel fuel burns, while infrequent in medical literature, pose significant risks and require specialized care. Further research and possibly regulatory measures may be warranted to mitigate these risks and prevent severe injuries.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"303-306"},"PeriodicalIF":1.5,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141457100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Emerging Role of GLP-1 Agonists in Burn Care: What Do We Know? GLP-1 激动剂在烧伤护理中的新作用:我们知道什么?
IF 1.5 4区 医学
Journal of Burn Care & Research Pub Date : 2025-03-04 DOI: 10.1093/jbcr/irae189
Artur Manasyan, Brigette Cannata, Erin Ross, Sasha Lasky, Eloise W Stanton, Nicolas Malkoff, Zachary Collier, Maxwell B Johnson, Timothy Justin Gillenwater
{"title":"The Emerging Role of GLP-1 Agonists in Burn Care: What Do We Know?","authors":"Artur Manasyan, Brigette Cannata, Erin Ross, Sasha Lasky, Eloise W Stanton, Nicolas Malkoff, Zachary Collier, Maxwell B Johnson, Timothy Justin Gillenwater","doi":"10.1093/jbcr/irae189","DOIUrl":"10.1093/jbcr/irae189","url":null,"abstract":"<p><p>Glucagon-like peptide-1 (GLP-1) agonists mimic the action of GLP-1, a hormone that regulates blood glucose levels via stimulation of insulin release and inhibition of glucagon secretion. After the burn, the current literature suggests that the use of GLP-1 agonists results in less insulin dependence with similar glucose control and hypoglycemic events to patients receiving a basal-bolus insulin regimen. Glucagon-like peptide-1 agonists may also promote wound healing through various mechanisms including angiogenesis and improved keratinocyte migration. Despite the potential benefits, GLP-1 agonists reduce gastrointestinal motility which impacts their widespread adoption in burn care. This dysmotility can result in inadequate nutrition delivery, unintentional weight loss, and is a potential aspiration risk. The net impact of these medications on patients with burns is unclear. Given their potential to demonstrate the safety, efficacy, and optimal dosing of various GLP-1 agonists in acute burn management.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"481-486"},"PeriodicalIF":1.5,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142466338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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