Journal of Burn Care & Research最新文献_第3页

Reliability of Methicillin-Resistant Staphylococcus aureus (MRSA) Nasal Swab Screening for Predicting MRSA Burn Infections. 耐甲氧西林金黄色葡萄球菌（MRSA）鼻拭子筛查预测MRSA烧伤感染的可靠性。

IF 1.5 4区医学

Journal of Burn Care & Research Pub Date : 2025-06-24 DOI: 10.1093/jbcr/iraf117

Max L Silverstein, Yvonne Karanas, Clifford C Sheckter

{"title":"Reliability of Methicillin-Resistant Staphylococcus aureus (MRSA) Nasal Swab Screening for Predicting MRSA Burn Infections.","authors":"Max L Silverstein, Yvonne Karanas, Clifford C Sheckter","doi":"10.1093/jbcr/iraf117","DOIUrl":"https://doi.org/10.1093/jbcr/iraf117","url":null,"abstract":"Infection is the primary cause of death among burn-injured patients, with soft tissue infection trailing only pneumonia as the most common source of sepsis. Methicillin-resistant Staphylococcus aureus (MRSA) has become endemic in burn units, resulting in the frequent initiation of empiric vancomycin therapy. MRSA nasal swab screening rapidly identifies patients who are MRSA-colonized, informing contact precaution and decontamination protocols. We hypothesized that MRSA nasal swab results could also be used to reliably predict results of wound cultures obtained from infected burns. We performed a retrospective review of all 250 patients who underwent weekly nasal swab screening and developed a burn infection in our unit over a 36-month period. By comparing nasal screening results to bacterial cultures, we determined test performance metrics for MRSA nasal swabs: sensitivity 64.1%, specificity 96.2%, positive predictive value (PPV) 75.8%, and negative predictive value (NPV) 93.5%. Nasal swabs were slightly more sensitive for predicting community-acquired MRSA infections versus those that were likely hospital-acquired. 30 patients (76.9%) presented with community-acquired MRSA infections; of those, 20 (66.7%) had tested positive for MRSA colonization on nasal screen. 9 patients (23.1%) developed hospital-acquired MRSA infections; 5 (55.6%) had tested positive for MRSA on a preceding nasal swab. The NPV calculated here indicates that patients who test negative for MRSA colonization by recent nasal swab are highly unlikely to have a burn infection caused by MRSA. Burn centers should employ universal MRSA nasal screening and de-escalate MRSA antibiotic coverage when treating burn infections in patients with a negative nasal swab result.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thrombolytic Therapy in Prepubescent Pediatric Frostbite Patients. 青春期前儿童冻伤患者的溶栓治疗。

IF 1.5 4区医学

Journal of Burn Care & Research Pub Date : 2025-06-23 DOI: 10.1093/jbcr/iraf116

Melanie McCormick, Nicholas Larson, Rob Newsom, Sam A Miotke, Alexandra M Lacey

引用次数: 0

Global Characteristics and Outcomes of Massive Burn Injuries. 大面积烧伤的全球特征和结果。

IF 1.5 4区医学

Journal of Burn Care & Research Pub Date : 2025-06-23 DOI: 10.1093/jbcr/iraf113

Fuat Baris Bengur, Daniel Najafali, Hilary Y Liu, Megan Najafali, Saeid Rezaei, José Antonio Arellano, Logan G Galbraith, Mare G Kaulakis, Erik Reiche, Raman Mehrzad, Sameer A Patel, Quincy K Tran, Victor E Stams, Francesco M Egro

{"title":"Global Characteristics and Outcomes of Massive Burn Injuries.","authors":"Fuat Baris Bengur, Daniel Najafali, Hilary Y Liu, Megan Najafali, Saeid Rezaei, José Antonio Arellano, Logan G Galbraith, Mare G Kaulakis, Erik Reiche, Raman Mehrzad, Sameer A Patel, Quincy K Tran, Victor E Stams, Francesco M Egro","doi":"10.1093/jbcr/iraf113","DOIUrl":"https://doi.org/10.1093/jbcr/iraf113","url":null,"abstract":"Patients with massive burn injuries represent a unique patient cohort because they are associated with high morbidity and mortality while requiring high care intensity. This study aimed to compare the characteristics and outcomes of patients with massive burns (TBSA ≥40%) versus those without, by utilizing the WHO Global Burn Registry. Descriptive statistics summarized demographic and burn characteristics. Multivariable logistic regression quantified the impact of massive burns on mortality, likelihood of surgical intervention, and functional impairment among survivors. Among 9274 patients in the database, 1828 (19.7%) had massive burns, with a median TBSA of 55% (IQR: 45-75%). These patients were predominantly managed in low-resource settings (60%) and sustained higher rates of inhalation injury (48% vs. 7%, p<.001) and flame-based burns (83% vs. 40%, p<.001) compared to the non-massive burns cohort. Logistic regression showed that massive burns increased the odds of mortality (OR 7.25, 95%CI 6.08-8.65) and functional impairment (OR 1.36, 95%CI 1.004-1.81), while decreased the odds of undergoing surgical intervention (OR 0.55, 95%CI 0.48-0.62). Massive burns significantly predict higher mortality and long-term functional challenges while reducing the likelihood of surgical intervention. These findings underscore the need for tailored management strategies and comprehensive rehabilitation for this high-risk population, particularly in resource-limited settings.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Variability of Characterization of Total Body Surface Area in Burn Outcomes: A Burn Model System Study. 烧伤结果中全身表面积特征的可变性：一项烧伤模型系统研究。

IF 1.5 4区医学

Journal of Burn Care & Research Pub Date : 2025-06-23 DOI: 10.1093/jbcr/iraf114

Eloise W Stanton, Deja Nicholas, Andrew Humbert, Colleen M Ryan, Gretchen J Carrougher, Barclay T Stewart, Haig A Yenikomshian

{"title":"Variability of Characterization of Total Body Surface Area in Burn Outcomes: A Burn Model System Study.","authors":"Eloise W Stanton, Deja Nicholas, Andrew Humbert, Colleen M Ryan, Gretchen J Carrougher, Barclay T Stewart, Haig A Yenikomshian","doi":"10.1093/jbcr/iraf114","DOIUrl":"https://doi.org/10.1093/jbcr/iraf114","url":null,"abstract":"Total body surface area (TBSA) burned is critical for assessing burn extent and guiding acute treatment, but its role in predicting long-term outcomes remains underexplored. This study leverages the Burn Model Systems (BMS) database to evaluate TBSA's characterization and its predictive value for survivors' outcomes, aiming to propose standardized approaches for its use. Publications from the BMS database (1994-2024) were analyzed for TBSA characterization and its relationship to outcomes. Outcomes included patient-reported measures (e.g., quality of life, psychological well-being) and objective outcomes (e.g., physical recovery, complications). Descriptive statistics were used to summarize TBSA usage across studies and its influence on outcomes. Of 107 publications, 91 (85%) included TBSA data. Among these, 91% used TBSA as a continuous variable, 23% employed categorical methods, and 16% utilized both. Categorical TBSA stratification varied, with deciles (n = 6) and quintiles (n = 3) being most common, while others used inconsistent approaches. Approximately 32% of studies assessed TBSA's direct impact on outcomes such as physical and psychosocial recovery, return to work, and pain/itch. A quarter of studies included TBSA as a covariate without directly examining its predictive value. Of 32 papers reporting TBSA outcomes, 74.4% demonstrated significant impact on outcomes. TBSA is widely utilized but inconsistently characterized, with few studies directly assessing its role in long-term outcomes. Standardizing TBSA reporting could improve predictive accuracy, facilitate cross-study comparisons, and guide evidence-based care for burn survivors.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feasibility and Acceptability of a Narrative Medicine Intervention in a Burn Center. 烧伤中心叙事医学干预的可行性和可接受性。

IF 1.5 4区医学

Journal of Burn Care & Research Pub Date : 2025-06-20 DOI: 10.1093/jbcr/iraf115

Daniel H Grossoehme, Nicole Robinson, Anjay Khandelwal, Richard Lou, Gwendolyn Richner, Neil L McNinch, Sarah Friebert

{"title":"Feasibility and Acceptability of a Narrative Medicine Intervention in a Burn Center.","authors":"Daniel H Grossoehme, Nicole Robinson, Anjay Khandelwal, Richard Lou, Gwendolyn Richner, Neil L McNinch, Sarah Friebert","doi":"10.1093/jbcr/iraf115","DOIUrl":"https://doi.org/10.1093/jbcr/iraf115","url":null,"abstract":"Psychosocial sequelae from burn injuries may be significant for both patients and caregivers, affecting functional recovery. Narrative medicine, one aspect of medical humanities, uses guided reading, discussion, and writing to allow persons to feel seen and heard, and to reflect and express themselves. This low-cost, non-pharmacologic intervention may benefit persons recovering from a burn injury, as well as caregivers. A prospective, uncontrolled, feasibility and acceptability trial was carried out in a 12-bed regional burn center with six patients and six caregivers (not dyadic pairs). Feasibility was defined as a minimum threshold of 85% completed intervention sessions; acceptability was defined as a minimum enrollment rate of 35%. Anticipating a subsequent quasi-experimental design, candidate outcome variables (anxiety and emotional regulation) were measured for potential use. Participants' written texts were collected and analyzed using thematic analysis. The study was acceptable (35%) and feasible to deliver to burn patients (100%). Caregiver acceptability was low (under 35%), although it was feasible to deliver to caregivers (86%). Two candidate outcome variables (anxiety and emotional regulation) showed measurable change in the expected direction in both patients and caregivers. Thematic analysis yielded four themes: out of hospital stressors, hope and compassion, medical updates, and emotions. Meaningful contributions may be made by narrative medicine interventions, offering a low-cost, non-pharmacological option to reduce anxiety and regulate emotions. Results warrant revising the study design and proceeding with further development of this behavioral intervention.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144512020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A National Evaluation of Time to Surgery Following Burn Center Admission Utilizing the Burn Care Quality Platform Data. 利用烧伤护理质量平台数据对烧伤中心入院后的手术时间进行全国评估。

IF 1.5 4区医学

Journal of Burn Care & Research Pub Date : 2025-06-17 DOI: 10.1093/jbcr/iraf112

Eva Murphy, Anastasiya Ivanko, Jonathan E Schoen, Herb A Phelan, Sharven Taghavi, Bart Phillips, Erica Weichman-Murata, Nathanael Hevelone, Randy Kearns, Shelby Wilde, M Victoria P Miles, Jeffrey E Carter

{"title":"A National Evaluation of Time to Surgery Following Burn Center Admission Utilizing the Burn Care Quality Platform Data.","authors":"Eva Murphy, Anastasiya Ivanko, Jonathan E Schoen, Herb A Phelan, Sharven Taghavi, Bart Phillips, Erica Weichman-Murata, Nathanael Hevelone, Randy Kearns, Shelby Wilde, M Victoria P Miles, Jeffrey E Carter","doi":"10.1093/jbcr/iraf112","DOIUrl":"https://doi.org/10.1093/jbcr/iraf112","url":null,"abstract":"Burn injuries are a major cause of morbidity in the United States, affecting 600 000 individuals annually. Early surgical intervention improves outcomes and reduces complications; however, access to specialized burn care is limited, with only 135 burn centers nationwide. Timely surgery, particularly for large burns, is critical for preventing complications such as hypertrophic scarring (HTS) and infection while optimizing recovery. This study evaluates surgical timing across pediatric and adult burn patients to inform evidence-based practices. We analyzed data from the American Burn Association's Burn Care Quality Platform (2020-2023), including 99 195 patients (23 284 pediatric, 75 911 adult) admitted to 112 burn centers. Days from admission to first burn surgery were assessed, excluding cases with trauma or non-burn diagnoses. Surgical timing was compared by total body surface area (TBSA) burned and age group. Among pediatric patients, 34.6% (7247) underwent surgery, with a median time to surgery of 1 (IQR: 1-3) day; for adults, 49.3% (32052) underwent surgery, with a median of 2 (IQR: 1-4) days. Larger burns (≥20% TBSA) were treated slightly earlier, with median times of 1-3 days across groups. However, no statistically significant differences in surgical timing were observed by burn size in adults, whereas significant differences were found in the pediatric 20- 29% TBSA group (p=.035). Timely surgical intervention improves outcomes, yet delays in treating smaller burns highlight gaps in care. Future research should address referral guidelines, logistical barriers, and optimize surgical timing to improve outcomes and resource allocation in burn care.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to: Burn Injury Severity in Adults: Proposed Definitions Based on the National Burn Research Dataset. 修正：成人烧伤严重程度：基于国家烧伤研究数据集的拟议定义。

IF 1.5 4区医学

Journal of Burn Care & Research Pub Date : 2025-06-17 DOI: 10.1093/jbcr/iraf109

引用次数: 0

Prior Organ Transplant Increases Risk of Wound Infection After Burn Injury: A National Database Study. 既往器官移植增加烧伤后伤口感染的风险：一项国家数据库研究。

IF 1.5 4区医学

Journal of Burn Care & Research Pub Date : 2025-06-16 DOI: 10.1093/jbcr/iraf063

Rebecca Hohsfield, Hilary Y Liu, David Orozco, Mare G Kaulakis, José Antonio Arellano, Christopher J Fedor, Garth Elias, Alain Corcos, Jenny Ziembicki, Francesco M Egro

{"title":"Prior Organ Transplant Increases Risk of Wound Infection After Burn Injury: A National Database Study.","authors":"Rebecca Hohsfield, Hilary Y Liu, David Orozco, Mare G Kaulakis, José Antonio Arellano, Christopher J Fedor, Garth Elias, Alain Corcos, Jenny Ziembicki, Francesco M Egro","doi":"10.1093/jbcr/iraf063","DOIUrl":"https://doi.org/10.1093/jbcr/iraf063","url":null,"abstract":"Transplant recipients face unique challenges in burn injury management due to the use of immunosuppressive therapies, which increase susceptibility to infection, impair wound healing, and heighten the risk of drug-related toxicity. This study evaluates whether a history of organ transplantation serves as an independent risk factor for wound infection in burn patients. A retrospective case-control study was conducted for burn patients from the Burn Care Quality Platform Registry from 2013 to 2022. Patients with a history of organ transplant were identified, and a matched cohort of non-transplant patients was selected based on age and total body surface area burned. The data collected included demographics, injury characteristics, surgical interventions, and clinical outcomes. Of 106 967 burn patients, 50 with a history of organ transplantation were identified. Transplant patients had a significantly higher wound infection rate compared to non-transplant patients (26% vs 6%, P = .006). No significant differences were observed in hospital length of stay (P = .65), intensive care unit length of stay (P = .74), days on a ventilator (P = .77), number of surgical operations (P = .23), or mortality rates (P > .99). Burn patients with a history of organ transplantation are at a significantly higher risk of wound infection. Tailored management strategies may be necessary to mitigate infection risk and optimize outcomes in this vulnerable population.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

One Team: Identifying Prehospital Provider Needs for Burn Patient Outreach and Education. 一个团队：确定院前提供者对烧伤患者外展和教育的需求。

IF 1.5 4区医学

Journal of Burn Care & Research Pub Date : 2025-06-12 DOI: 10.1093/jbcr/iraf110

Ronnie Adams, Stephen Elmgren, Yuk Ming Liu, Laura Johnson, Lauren Nosanov

{"title":"One Team: Identifying Prehospital Provider Needs for Burn Patient Outreach and Education.","authors":"Ronnie Adams, Stephen Elmgren, Yuk Ming Liu, Laura Johnson, Lauren Nosanov","doi":"10.1093/jbcr/iraf110","DOIUrl":"https://doi.org/10.1093/jbcr/iraf110","url":null,"abstract":"Burns are among the most common traumatic injuries and are associated with significant morbidity and mortality; however, many prehospital providers remain unfamiliar with current management algorithms. Proper resuscitation is crucial to clinical outcomes, but care guidelines vary widely. We sought to characterize and evaluate the burn care provided by emergency medical service agencies in our metropolitan region to identify opportunities for improvement and education. Surveys were distributed to prehospital professionals, and emergency medical services clinical protocols were obtained for qualitative analysis. Survey design and analysis were conducted with Qualtrics. The 38 survey responses were from providers representing 19 emergency medical service agencies; 8 protocols were obtained and analyzed. Respondents were primarily paramedics (61%), and 34 (89.5%) had renewed their license in the past two years. Notably, 35/38 (92.1%) reported transporting five or fewer burn patients within the past year, and 28/35 (80.0%) stated they were not comfortable establishing vascular access through a burn wound. Continuing education was most commonly obtained through formal courses (65.7%), podcasts (42.1%), and departmental training (34.2%). Qualitative review of the protocols revealed varied formulas for fluid resuscitation. Approved pain medications included morphine, ketamine, and fentanyl; two agencies mentioned hydroxocobalamin in their protocol. Thermoregulation measures were mentioned in three protocols. Prehospital providers lack high-volume exposure to this patient population and exhibit low comfort levels. Minimal information on burns is included in regular continuing education. Practices differ between emergency medical service agencies, even though the quality of prehospital care has a sizeable impact on outcomes.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Workers' Compensation Benefits on Health-Related Quality of Life for Working Adults: A Burn Model System Investigation. 工人补偿福利对工作成年人健康相关生活质量的影响：烧伤模型系统调查。

IF 1.5 4区医学

Journal of Burn Care & Research Pub Date : 2025-06-11 DOI: 10.1093/jbcr/iraf111

Caitlin M Orton, Xinyao deGrauw, April B Hamilton, Gretchen J Carrougher, Jeffrey Schneider, Karen Kowalske, Shelley Wiechman, Michael Choo, Barclay T Stewart

{"title":"Impact of Workers' Compensation Benefits on Health-Related Quality of Life for Working Adults: A Burn Model System Investigation.","authors":"Caitlin M Orton, Xinyao deGrauw, April B Hamilton, Gretchen J Carrougher, Jeffrey Schneider, Karen Kowalske, Shelley Wiechman, Michael Choo, Barclay T Stewart","doi":"10.1093/jbcr/iraf111","DOIUrl":"https://doi.org/10.1093/jbcr/iraf111","url":null,"abstract":"Workers' compensation (WC) includes wage replacement, medical cost coverage, and vocational rehabilitation services. We aimed to examine the impact of WC on health-related quality of life (HRQOL) scores among working adults with burn injury. The Burn Model System National Database was queried for self-reported working adult participants who answered the Veterans RAND 12-Item Health Survey (VR-12) at discharge (pre-injury recall) and 6-, 12-, and 24-months post-injury. Participants were stratified into those with and without WC. HRQOL scores were calculated by transforming VR-12 responses to Short Form-6D (SF-12). Mixed-effects linear regression modeling was used to assess impact of WC on HRQOL scores over 2-years post-injury. 495 participants were analyzed (94 with WC, 401 without WC). Males accounted for 87% of WC beneficiaries and 72% of those without WC. Mean pre-injury HRQOL scores were 0.72 for WC beneficiaries and 0.73 for those without WC (p=.99) and decreased significantly in both groups at each study timepoint post-injury. Greater HRQOL loss was seen in WC beneficiaries compared to those without WC at 6-months (p=.07), 12-months (p=.02), and 24-months (p=.03) post-injury. All workers experienced a drop in HRQOL scores post-injury. WC beneficiaries experienced greater HRQOL loss than non-WC participants. These findings align with investigations among working adults with non-burn upper extremity and back injuries, suggesting there is opportunity to improve the delivery of WC benefits for all injured workers. To enhance vocational rehabilitation service delivery, the intensity of interventions should be tailored to person-specific needs, risks of complicated return-to-work, and unique recovery journeys.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0