Journal of Burn Care & Research最新文献

{"title":"Alternative Resting Ankle Foot Orthosis For Patients With Impaired Heel Integrity Post Burn Injury.","authors":"Kelsey Ziegler","doi":"10.1093/jbcr/iraf100","DOIUrl":"https://doi.org/10.1093/jbcr/iraf100","url":null,"abstract":"<p><p>The purpose of this case series was to describe an alternative resting ankle foot orthosis for range of motion maintenance in patients who were intolerant or inappropriate for traditional heel-relief ankle foot orthoses due to impaired soft tissue integrity of the posterior lower leg or heel post major burn injury. Anterior panel ankle foot orthoses were fabricated on 2 pediatric patients ages 8 and 11 years old with major burn injuries. Both patients experienced improvements in dorsiflexion range of motion to at least 0°. Neither patient experienced adverse effects that could be attributed to the ankle foot orthoses. The anterior panel ankle foot orthosis described in this case series appeared to be safe and effective for the included patients. Clinicians can use this information to assist with fabrication of alternative resting ankle foot orthoses for patients who are inappropriate for traditional methods of ankle contracture prevention and management.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Limited English Proficiency on Outcomes Following Burn Injury.","authors":"Andrea Rosmery Iturralde Carrillo, Larissa Epstein, Carina Franco, Jennie Caluya, Natalie Coca, Krista L Haines, Jason Heard, Soman Sen, Tina Palmieri, Kathleen S Romanowski","doi":"10.1093/jbcr/iraf099","DOIUrl":"https://doi.org/10.1093/jbcr/iraf099","url":null,"abstract":"<p><p>Studies indicate that surgical patients with limited English proficiency (LEP) experience longer hospital stays and higher emergency department (ED) recidivism. Burn care requires complex coordination for both inpatient and outpatient services, regardless of language preference. This study hypothesized that burn patients with LEP would have longer hospital stays, fewer follow-ups, and more ED visits. Following IRB approval, a retrospective chart review analyzed burn patients admitted between January 2018 and December 2019. Collected data included demographics, burn characteristics, outcomes, preferred language, and follow-up care. Statistical analysis was performed using SAS (version 9.4), employing Chi-square, Fisher Exact, Spearman Correlation, Wilcoxon 2-sample, and Kruskal-Wallis tests. A total of 751 patients (median age 46 years, IQR 26) were included, with 555 (73%) males and a median total body surface area (TBSA) burn of 6.5% (IQR 12). Among them, 15% had inhalation injuries, and 5% died. Sixty-one patients (8%) identified a preferred language other than English. LEP and English-speaking patients showed no significant differences in burn size (5.5% vs. 6.6%, p=0.32), mortality (3.3% vs. 4.7%, p=1), length of stay (8 vs. 9 days, p=0.43), or discharge to home (86.9% vs. 75.9%, p=0.44). However, LEP patients were more likely to have scheduled follow-ups (93.4% vs. 80.2%, p=0.04), attend visits (78.7% vs. 50.7%, p=0.0005), and revisit the ED (19.7% vs. 10.5%, p=0.03). These findings highlight disparities in discharge education and outpatient care, emphasizing the need for targeted interventions to improve post-burn recovery in LEP populations.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Preexisting Substance Use Disorders on Prolonged Opioid Use and Postoperative Complications After Burns.","authors":"Philong Nguyen, Joshua E Lewis, Isabelle J Carroll, Joshua Wang, Mbinui Ghogomu, Blancheneige Beohon, Amina El Ayadi, Steven Wolf, Juquan Song","doi":"10.1093/jbcr/iraf098","DOIUrl":"https://doi.org/10.1093/jbcr/iraf098","url":null,"abstract":"<p><p>Previous studies have linked preexisting substance use disorders to adverse postoperative outcomes in burn patients, yet their impact on opioid use remains unclear. This retrospective cohort study compares the effects of various substances on opioid use after burns and aims to analyze the risks and whether they differ among substances. The TriNetX database was queried for burn patients aged 18 years and older with preexisting alcohol, cannabis, or tobacco use disorders, who were placed in their respective cohorts. These patients were matched to a non-substance use disorder cohort using propensity score matching based on demographics, mental health, pain syndromes, and burn severity. The measured outcomes assessed were opioid use, wound infection, wound disruption, and postprocedural pain. Risk ratios and 95% confidence intervals were calculated at 3 months and 12 months post-burn. After matching, patients with preexisting substance use disorders had significantly higher risk ratios for prolonged opioid use, wound infections, and wound healing disruptions at both 3- and 12-months compared to matched patient control cohorts. Additionally, all patient cohorts also exhibited increased risk of postprocedural pain. Burn patients with preexisting substance use disorders face a significantly higher risk of prolonged opioid use and postoperative complications at both 3- and 12-month post-burn injury. The alcohol cohort patients were associated with the greatest increase in opioid use and postoperative complications, while the tobacco patient cohort presented with the highest wound disruption rates at 3- and 12-months post-burn.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Burn disasters in North Carolina: An Analysis of Four Major Incidents with a Look to the Future.","authors":"Booker T King, Felicia N Williams, Alexandra Coward, Lori Chrisco, Christopher Derek Miller, Erin R Hanlin, Cynthia Laurer, Kevin Bailey, James Holmes, Randy D Kearns","doi":"10.1093/jbcr/iraf095","DOIUrl":"https://doi.org/10.1093/jbcr/iraf095","url":null,"abstract":"<p><p>This paper examines the medical response to four significant burn disasters in the North Carolina: the Pope Air Force Base disaster, the ConAgra/Garner food plant fire, the Imperial Foods/Hamlet chicken plant fire, and the West Pharmaceutical/Kinston fire. Each incident resulted in substantial injuries and fatalities, necessitating a coordinated medical response that involved local hospitals, emergency medical services, and burn and trauma centers. This analysis highlights the effectiveness of triage, mobilization of resources, medical transport and the role of specialized centers in managing burn casualties. Furthermore, the paper discusses the existing local, state, regional, and national burn disaster response plans, emphasizing the importance of collaboration among various agencies. In the context of North Carolina, the state's disaster preparedness strategies are evaluated, revealing strengths in outreach and training but also identifying gaps in resource allocation and inter-agency communication. Opportunities exist for improvements in communication with use of telemedicine and refining training with the utilization of artificial intelligence. This comprehensive review underscores the critical need for ongoing assessment and refinement of disaster response frameworks to better protect communities from the devastating impacts of burn incidents.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Application of Metagenomic Next-Generation Sequencing of Microbial Cell-free DNA in Ruling Out Invasive Fungal Infection in a Patient with Thermal Burn Wounds: A Case Report.","authors":"Koree Begovic, Lucas Bryant, Keith Glenn, Sean Gamble","doi":"10.1093/jbcr/iraf094","DOIUrl":"https://doi.org/10.1093/jbcr/iraf094","url":null,"abstract":"<p><p>Patients with severe thermal burns are highly susceptible to invasive fungal infections due to compromised skin integrity, prolonged hospitalization, and immunosuppression. Traditional diagnostic methods, such as cultures and tissue biopsies with histopathology, have limitations. Metagenomic next-generation sequencing (mNGS) of microbial cell-free DNA in plasma is a rapid, non-invasive diagnostic tool for detecting fungal elements in the bloodstream. The aim of this report is to present the utility of this method to aid in ruling out an invasive fungal infection in a patient with burns. This case involves a middle-aged male with extensive thermal burns who developed sepsis, with concerns of invasive fungal infection after fungal elements were detected in wound cultures of skin grafts. However, β-D-glucan and galactomannan assays were negative, and metagenomic next-generation sequencing did not detect fungal DNA in plasma. Histopathological examination of tissue biopsies later confirmed the absence of angioinvasion, and blood cultures showed no evidence of fungemia. As a result, antifungal therapy was safely discontinued without clinical deterioration. While metagenomic next-generation sequencing has shown potential for negative predictive value in immunocompromised patients, its role in patients with burns warrants further investigation. Integrating metagenomic next-generation sequencing with conventional diagnostic methods may improve clinical decision-making, reduce unnecessary empirical antifungal treatment, and enhance patient outcomes.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neutrophil Prealbumin Ratio as a Potential Predictive Marker for Severe Burn Patients' Prognosis.","authors":"Ozan Namdaroglu, Hilmi Yazıcı, Ahmet Cem Esmer, Mehmet Alperen Ugur, Ahmet Erim Erdogan, Ahmet Mucteba Ozturk, Ahmet Deniz Ucar, Mehmet Yildirim","doi":"10.1093/jbcr/iraf096","DOIUrl":"https://doi.org/10.1093/jbcr/iraf096","url":null,"abstract":"<p><p>Severe burn injuries are associated with high morbidity and mortality, necessitating reliable prognostic markers for effective patient management. The Neutrophil-to-Prealbumin Ratio (NPR), which combines inflammatory and nutritional status, has emerged as a potential prognostic tool. This study aimed to evaluate the prognostic value of NPR in predicting mortality among severe burn patients. Severe burn patients admitted to the Burn Treatment Center between January 2020 and December 2023 were retrospectively analyzed. Patients were categorized into survivor and non-survivor groups. Inflammatory markers, including NPR, Neutrophil-to-Lymphocyte Ratio (NLR), Systemic Inflammatory Response Index (SIRI), and Platelet-to-Lymphocyte Ratio (PLR), were evaluated for their association with mortality using Receiver Operating Characteristic (ROC) curve analysis and multivariate logistic regression. A total number of 357 patients were included in the study. Of the 357 patients, 101 (28.3%) were non-survivors. The non-survivor group had significantly higher TBSA, full-thickness burns, inhalation injuries, and blood transfusion requirements (p<0.001). ROC curve analysis demonstrated that NPR had the highest area under the curve (AUC=0.760). A cut-off value of 0.75 for NPR was associated with a significant increase in mortality risk. Multivariate logistic-regression identified NPR as an independent predictor of mortality alongside TBSA, full-thickness burns, and inhalation injuries. NPR is a promising prognostic marker for mortality in severe burn patients, outperforming traditional inflammatory markers. Its integration of inflammatory and nutritional status provides a comprehensive assessment of patient risk. Further prospective studies are needed to validate these findings and explore the broader applications of NPR in burn care and other critical settings.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypothyroidism in Severe Burn Patients Associated with Increased Risk of Musculoskeletal Complications and Decreased Risk of Mortality.","authors":"Isabel Obias, Dalton Amador, Sudhanvan Iyer, Amina El Ayadi, Georgiy Golovko, Steven E Wolf, Juquan Song","doi":"10.1093/jbcr/iraf090","DOIUrl":"https://doi.org/10.1093/jbcr/iraf090","url":null,"abstract":"<p><p>Severe burn patients are prone to developing various musculoskeletal, dermatological, and cardiovascular complications, and hypothyroidism is associated with derangements of these same systems. This study aims to explore the association between hypothyroidism and the emergence of these complications in severe burn patients. Patients with severe burns, defined as those encompassing ≥ 20% total body surface area, were identified in the TriNetX United States Collaborative Network and were categorized into two groups based on a history of hypothyroidism. Risk ratios and differences of contractures, undergoing graft procedures, graft complications, amputations, and various infections and cardiovascular complications were generated using the database's measure of association analysis. The hypothyroidism cohort showed a greater risk of developing contractures (risk ratio [RR], 1.667; 95% confidence interval [CI], [1.207, 2.302]; p = 0.002), skin infections (RR, 1.885; CI, [1.192, 2.980]; p = 0.006), and urinary tract infections (RR, 1.950; CI, [1.155, 3.292]; p = 0.011) within six months of insult. The hypothyroidism cohort showed a decreased risk of mortality (RR, 0.688; CI, [0.516, 0.915]; p < 0.010), undergoing graft procedures (RR, 0.647; CI, [0.518, 0.807]; p < 0.001), and vasopressor use (RR, 0.806; CI, [0.667, 0.974]; p = 0.025) in this same time period. In conclusion, hypothyroidism in severe burn patients is associated with an increased risk of developing contractures and skin and urinary tract infections and a decreased risk of mortality, undergoing graft procedures, and vasopressor use.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of the Endothelial, Coagulofibrinolytic and Inflammatory Profile in Burn Patients after Resuscitation with Fresh Frozen Plasma.","authors":"Amanda M Soo Ping Chow, Anthony E Pusateri, Tuan D Le, Thomas Orfeo, Matthew Gissel, Maria Cristina Bravo, Melissa McLawhorn, Lauren T Moffatt, Jeffrey W Shupp","doi":"10.1093/jbcr/iraf092","DOIUrl":"https://doi.org/10.1093/jbcr/iraf092","url":null,"abstract":"<p><p>Severe burn injuries are associated with endothelial, coagulopathic, and inflammatory dysfunction, requiring resuscitation; this is most often performed with intravenous crystalloids. Colloids, like fresh frozen plasma (FFP), can be used as adjuncts. This prospective observational cohort study investigated whether the varying factor and protein concentrations in a unit of FFP, as well as its allogenic nature, affected the preexisting prothrombotic, fibrinolytic and hyperinflammatory state in burn shock in a group of patients with ≥20% total body surface area (TBSA) who receive transfused plasma as part of the standard of care for resuscitation at a regional burn center. Blood samples were collected immediately prior to administration of the first unit of FFP (Pre-Unit) and immediately after administration of the first unit of FFP (Post-Unit). Concentrations of 31 plasma biomarkers were quantified and compared using paired t-test or a Wilcoxon signed-rank test. Data presented as median (interquartile range). Of the 33 patients included, the median TBSA burn of 34.0% (27.3-45.5). Post-Unit plasma concentrations were decreased compared to Pre-Unit concentrations in factor VIII [329 (201.9-474.1) vs 277 (189.5-438.1) %], fibrinogen [322 (295.3-412.8) vs 305 (285.3-388.5) mg/dL], protein C [105 (96.0-111.5) vs 102 (91.5-112.0) %], total tissue factor pathway inhibitor (TFPI) [69.7 (51.1-96.3) vs 67.7 (50.9-84.5) ng/mL], free TFPI [18.2 (14.2-21.8) vs 16.8 (12.9-21.1) ng/mL], activated/inactivated thrombin-activatable fibrinolysis inhibitor [55.1 (40.7-80.4) vs 48.7 (38.4-64.4) ng/mL], C1 esterase inhibitor [149.6 (132.3-222.1) vs 119.6 (110.4-151.6) %], and TNF-α receptor 1 [2010 (1451-3535) vs 1815 (1418-3189) pg/mL] (p≤0.05). The 23 other biomarkers did not change. While there were small but statistically significant reductions in 8 markers of coagulation, antifibrinolysis and inflammation, the Post-Unit concentrations either remained within or moved closer to the expected reference ranges. After initial transfusion of FFP, there were no clinically significant changes in the preexisting prothrombotic, fibrinolytic, endothelial or inflammatory biological profile.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distinct Transcriptome Signatures Associated With Mortality and Prolonged Recovery Following Burn Injury.","authors":"Burook Misganaw, Desiree N Pinto, Tuan D Le, Anthony Pusateri, Aarti Gautam, Bonnie C Carney, Lauren T Moffatt, Jeffrey W Shupp, Rasha Hammamieh","doi":"10.1093/jbcr/iraf012","DOIUrl":"https://doi.org/10.1093/jbcr/iraf012","url":null,"abstract":"<p><p>A dysregulated immune response after severe burn injury is associated with detrimental short and long-term clinical outcomes. Key changes to gene expression within the first 24 h after burn injury have been identified, but longitudinal data is lacking. Therefore, this study aims to characterize gene expression during the first 3 weeks after burn injury and identify specific genes and pathways associated with distinct clinical outcomes. Patients presenting within 4 h of injury had blood RNA isolated for microarray gene expression at admission and set timepoints to 21 days. Inter- and intra-group comparisons were performed between 4 groups (G1 died within 7 days; G2 died after 7 days; G3 discharged after 7 days; and G4 discharged within 7 days). A total of 17 289 transcripts were quantified from 116 patients. At admission, there were 110, 80, and 31 differentially expressed genes in G1, G2, and G3, respectively, compared to G4, and were largely nonoverlapping. Longitudinal intra-group analyses also showed distinct group- and time-dependent patterns. Upregulation of genes and pathways related to the innate immune response and unfolded protein response predominated during early time points, while persistent upregulation of coagulation pathways and downregulation of immune-related pathways were identified days to weeks following injury. Overall, burn injury induces widespread transcriptomic responses, with larger and more sustained changes observed in patients with worse clinical outcomes. These gene expression signatures reveal underlying molecular mechanisms that occur immediately following injury and may have prognostic and diagnostic utility in the care of burn-injured patients.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"National Estimates and Outcomes for Supplemental Home Oxygen Therapy Injuries-a Burn Care Quality Platform Analysis.","authors":"Clifford Sheckter, Eloise Stanton, Karla Klas, Bart Phillips, Rebecca Coffey, Alisa Savetamal, Lucy Wibbenmeyer","doi":"10.1093/jbcr/iraf087","DOIUrl":"https://doi.org/10.1093/jbcr/iraf087","url":null,"abstract":"<p><p>The incidence of admissions for burn and inhalation injuries related to home oxygen therapy remains poorly defined in the U.S. We analyzed the American Burn Association's Burn Care Quality Platform (BCQP) database (2013-2022) to generate national estimates of supplemental home oxygen therapy-related injuries and outcomes. Text string extraction identified cases using multiple search permutations related to home oxygen use. Patient demographics, injury characteristics, and inpatient outcomes were described. Logistic regression assessed predictors of oxygen therapy injuries, and Poisson regression estimated adjusted incidence rates. Of 207,364 burn admissions, 79,114 (28%) contained injury descriptions, with 3.0% (2,360 cases) attributed to home oxygen therapy. These patients had a median age of 65 years (IQR: 59-71), mean total body surface area (TBSA) of 4.1%, were predominantly male (62.6%) and white (79.0%). Medicare was the most common payer (57.7%). Inhalation injury was present in 11.4%, mean length of stay (LOS) was 8 days, and inpatient mortality was 6.1%. Smoking was the leading ignition source (63%), followed by cooking/stove (4%), while 22% had no identified cause. The adjusted incidence rate of supplemental home oxygen injuries was 3.6% (95% CI: 2.7-2.9%, p < 0.001), with a significant annual increase (incidence rate ratio: 1.03, 95% CI: 1.02-1.04). Oxygen therapy-related injuries account for 1,088 (95% CI: 1,065-1,113) burn admissions per year in the U.S. Despite smaller TBSA burns, mortality was twice the national average for burn patients, and for survivors, the odds of discharge home were 15% less likely. Targeted prevention strategies are needed to mitigate this growing public health problem.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}