Journal of Burn Care & Research最新文献_第10页

Obesity's Impact on Pediatric Scald Burns: How Much Weight Does It Carry? 肥胖对儿童烫伤的影响：它承载了多少重量？

IF 1.5 4区医学

Journal of Burn Care & Research Pub Date : 2025-04-18 DOI: 10.1093/jbcr/iraf054

Christian Hudson-Bradford, Rachael M Galvin, Elika Ridelman, Darina N Malinova, Justin D Klein, Christina M Shanti

{"title":"Obesity's Impact on Pediatric Scald Burns: How Much Weight Does It Carry?","authors":"Christian Hudson-Bradford, Rachael M Galvin, Elika Ridelman, Darina N Malinova, Justin D Klein, Christina M Shanti","doi":"10.1093/jbcr/iraf054","DOIUrl":"https://doi.org/10.1093/jbcr/iraf054","url":null,"abstract":"Childhood obesity is a growing public health concern in the United States, yet its impact on wound healing and surgical outcomes in pediatric burn patients remains understudied. This study investigates the relationship between obesity and clinical outcomes in pediatric patients with scald burns. A retrospective review of 389 pediatric patients (aged 1 month to 18 years) admitted to a regional burn center with ≥5% TBSA scald burns from 2015 to 2024 was conducted. Patients were categorized by weight-for-length (WFL) or body mass index (BMI) percentiles using the Centers for Disease Control and Prevention (CDC)/World Health Organization (WHO) growth charts. ANOVA and chi-square analyses found no significant differences in wound healing time across BMI or WFL categories. Similarly, no significant associations were observed between BMI/WFL groups and scar management or late grafting. However, a moderate relationship (p = 0.020) was identified between higher BMI and grafting during index admissions in older children. These findings suggest that obesity does not significantly impair wound healing but may influence surgical decisions in pediatric burn care. Further research is needed to explore these trends and guide tailored treatment protocols for obese pediatric patients.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early Post-Operative Mobilization After Treatment of Burn Wounds with Autologous Skin Cell Suspension is Safe. 自体皮肤细胞悬浮液治疗烧伤创面术后早期活动是安全的。

IF 1.5 4区医学

Journal of Burn Care & Research Pub Date : 2025-04-15 DOI: 10.1093/jbcr/iraf038

Rohit Mittal, Jenna Kelly, Steven Alexander Kahn

{"title":"Early Post-Operative Mobilization After Treatment of Burn Wounds with Autologous Skin Cell Suspension is Safe.","authors":"Rohit Mittal, Jenna Kelly, Steven Alexander Kahn","doi":"10.1093/jbcr/iraf038","DOIUrl":"https://doi.org/10.1093/jbcr/iraf038","url":null,"abstract":"Standardized criteria for mobilization of the post-operative burn patient do not currently exist. Even the term \"early mobilization\" is not well defined. Use of autologous skin cell suspension (ASCS) with or without split-thickness skin grafts (STSG) has improved patient outcomes. The purpose of this study is to evaluate the safety of early post-operative mobilization, defined as mobilization with rehabilitation team within 48h of surgical treatment, in patients who were treated with ASCS and a polylactic acid dressing. This is a single-center, retrospective review over a 10-month period of patients who presented with deep partial thickness and full-thickness burns. All burn wounds included in the study underwent surgical treatment of their burns with ASCS or ASCS+STSG. After surgical treatment, any patients/areas with post-operative restrictions were noted. All patients without restrictions were allowed active and/or passive range of motion (AROM or PROM) of the treated area and out of bed (OOB) mobilization starting on POD0. In total, 29 patients were treated with 77 separate areas undergoing surgical treatment with ASCS or ASCS + STSG; 79% of these areas involved joints. All patients underwent either AROM or PROM with the burn therapy team by POD2. Of the wounds treated with ASCS alone, 5% required patch grafting, and no graft loss was noted in those treated with STSG+ASCS. This study serves as a proof of concept that early post-operative mobilization in burn patients undergoing grafting and ASCS is safe and is not associated with graft loss, including areas involving joints.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of shared genes and immune profiling for pathological scar. 病理性瘢痕的共享基因鉴定和免疫谱分析。

IF 1.5 4区医学

Journal of Burn Care & Research Pub Date : 2025-04-12 DOI: 10.1093/jbcr/iraf046

Shuqian Dou, Yue Deng, Di Wang, Wenjun Liu

{"title":"Identification of shared genes and immune profiling for pathological scar.","authors":"Shuqian Dou, Yue Deng, Di Wang, Wenjun Liu","doi":"10.1093/jbcr/iraf046","DOIUrl":"https://doi.org/10.1093/jbcr/iraf046","url":null,"abstract":"Pathological scar (PS), encompassing hypertrophic scars (HS) and keloids, significantly impacts skin morphology and functions. Evidence suggests both exhibit hyperactive immune-inflammatory responses, yet research remains limited. This study used bioinformatics to explore shared genes and immune response characteristics in PS. Transcriptomic datasets (GSE181540 and GSE158395) were explored to investigate differentially expressed genes (DEGs) between normal skin and HS/ keloids using the \"limma\" package. Overlapping up- and downregulated genes were visualized via a Venn diagram and subjected to GO and KEGG enrichment to highlight immune-related processes, particularly in chemotaxis, indicating immune response abnormalities in both scar types. Differentially expressed immune-associated genes (DEIGs) were identified by overlapping DEGs with immune-associated genes. Seventy-eight DEIGs were mapped to protein-protein interaction (PPI) networks, revealing VCAM1, THBS1, and SERPINE1 as the key hub genes. Immunohistochemical staining showed these genes were highly expressed in keloid and HS tissues but expressed at lower levels in normal skin. Ultimately, immune cell infiltration analysis unveiled increased immune cell proportions in HS and keloids, with keloid tissue displaying higher immune cell abundance.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Experiences from Burn Registry Pilot Study in Northern India: Patient Profile and Implementation Perspectives. 印度北部烧伤登记试点研究的经验：患者概况和实施观点。

IF 1.5 4区医学

Journal of Burn Care & Research Pub Date : 2025-04-10 DOI: 10.1093/jbcr/iraf042

Vikash Ranjan Keshri, Santosh Kumar Sharma, Pratishtha Singh, Shivangi Saha, Brijesh Mishra, Mohammed Fahud Khurram, Mohit Jain, Pranay Singh Chakotiya, Manoj Kumar Jha, Maneesh Singhal, Tanu Jain, Jagnoor Jagnoor

{"title":"Experiences from Burn Registry Pilot Study in Northern India: Patient Profile and Implementation Perspectives.","authors":"Vikash Ranjan Keshri, Santosh Kumar Sharma, Pratishtha Singh, Shivangi Saha, Brijesh Mishra, Mohammed Fahud Khurram, Mohit Jain, Pranay Singh Chakotiya, Manoj Kumar Jha, Maneesh Singhal, Tanu Jain, Jagnoor Jagnoor","doi":"10.1093/jbcr/iraf042","DOIUrl":"https://doi.org/10.1093/jbcr/iraf042","url":null,"abstract":"In India, burns represent a serious public health concern due to high death and disability rates. A national burn registry was proposed under the National Program on Prevention and Management of Burn Injuries. This study reports experiences from the first pilot burn registry in India, presenting patient profiles and implementation perspectives. Five burn centres were selected to implement a prospective, multicentric burn registry in northern India. Every burn patient at the study sites who met the inclusion criteria was recruited. Patients' sociodemographic and burn injury profiles, determinants of mortality, and predictors of poor recovery outcome (death or discharge with disability) are presented based on descriptive, bivariate and binary logistic regression analyses. From August 2020 to March 2022, a total of 908 patients were enrolled, with 61% being male and 39% female. Approximately 43% of acute burn patients were referred from other health facilities. The most frequent causes of burns were flame (37%), hot liquid (28%), and electric (28%). Accidental burns accounted for 88% of cases, with 73% occurring at patients' homes, and 48% being classified as major burns (≥20% Total Body Surface Area [TBSA]). Mortality was significantly higher among female patients with TBSA higher than 40% and non-accidental burns. The odds of poor recovery were higher for TBSA >40%, electric burns, and non-accidental burns. The implementation experience highlights the need to broaden the scope of the burn registry to include more comprehensive data, which can enhance the planning and delivery of burn care services.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Decrease in Total Leukocyte Count is Associated with Acute Kidney Injury After Severe Burn. 白细胞总数减少与严重烧伤后急性肾损伤有关。

IF 1.5 4区医学

Journal of Burn Care & Research Pub Date : 2025-04-08 DOI: 10.1093/jbcr/iraf039

Julie A Rizzo, Jason M Thomas, James K Aden, Steven G Schauer, Jan-Michael Van Gent, Wylan C Peterson, Luke J Hoffman, Jose Salinas, Laura S Johnson

{"title":"Decrease in Total Leukocyte Count is Associated with Acute Kidney Injury After Severe Burn.","authors":"Julie A Rizzo, Jason M Thomas, James K Aden, Steven G Schauer, Jan-Michael Van Gent, Wylan C Peterson, Luke J Hoffman, Jose Salinas, Laura S Johnson","doi":"10.1093/jbcr/iraf039","DOIUrl":"https://doi.org/10.1093/jbcr/iraf039","url":null,"abstract":"Leukocytosis is common after burn injury from profound systemic inflammatory response. Total leukocyte count (TLC) often decreases 72-96 hours post-injury. The incidence of early (<72 hours) leukopenia has not been previously described; this analysis sought to determine if early and extreme decreases in TLC was associated with increased fluid requirements or resuscitation-related outcomes in patients after burn injury. The Burn Navigator (BN) database is composed of 300 patients with > 20% TBSA and > 40kg that were resuscitated utilizing the BN clinical decision support system. Patients were split into two groups based on decrease in TLC from admission of greater than versus less than 15,000 cells per microliter. Demographics, resuscitation volumes, resuscitation-related complications and 7-day survival were collected. Of the 295 patients in the analysis, patients with greater than 15-point decrease in WBC from admission had more full-thickness burns (14.2 [2,36]) and greater TBSA (41 [30.2, 57.4]) than those with less than a 15-point decrease (7.7 [0.3, 14.8], p <0.001), 27.5 [23, 36], p < 0.001). Patients with greater than a 15-point WBC drop had a significantly higher incidence of admission myoglobinuria and AKI in the first 48 hours even after adjusting for TBSA. Survival at 7 days did not differ (66.7% vs 83.7%, p>0.05) when adjusting for TBSA. A decrease in WBC of at least 15 points after admission was associated with early AKI and a significantly higher incidence of admission myoglobinuria. Future studies need to investigate the mechanism behind this association and possible early interventions.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Home Oxygen Therapy in Burn Patients: A Single-Center Five-Year Analysis. 烧伤患者家庭氧疗：单中心5年分析。

IF 1.5 4区医学

Journal of Burn Care & Research Pub Date : 2025-04-08 DOI: 10.1093/jbcr/iraf044

Anna Fouty, Andrew Haiflich, Chandler S Hinson, Ashley Y Williams, Caleb Butts, Andrew C Bright

{"title":"Home Oxygen Therapy in Burn Patients: A Single-Center Five-Year Analysis.","authors":"Anna Fouty, Andrew Haiflich, Chandler S Hinson, Ashley Y Williams, Caleb Butts, Andrew C Bright","doi":"10.1093/jbcr/iraf044","DOIUrl":"https://doi.org/10.1093/jbcr/iraf044","url":null,"abstract":"Home oxygen therapy (HOT) is a common treatment for chronic pulmonary diseases, yet many patients on HOT are current or former smokers, increasing their risk for burn injuries. A prior national review (2002-2011) highlighted a significant rise in HOT-related burns. To understand this trend, we conducted a retrospective review of all burn patients admitted to our tertiary burn center from 2019 to 2023. Of all burn patients admitted, 2% (52 patients) had documented HOT use. Among the patients on HOT admitted for burns, 30 (57.7%) sustained burns directly related to HOT. Of these 30 HOT-related burns, 26 (87%) were attributed to cigarette smoking. HOT-related burns accounted for 1.1% of all burn admissions. Patients with HOT related burns were older, had more comorbidities, and were more likely to present with facial burns, inhalation injuries, and prolonged hospitalizations. Patients on HOT who sustained burns had a significantly higher mortality risk, with an odds ratio of 5.9 compared to non-HOT burn patients. Active smoking was identified as the primary risk factor for HOT-related burns. Despite smoking cessation being the ultimate goal for patients on HOT, many still continue to smoke. Targeted education on burn prevention and safety measures for active smokers on HOT is crucial for reducing morbidity and mortality. This study underscores the need for enhanced safety protocols and patient education to mitigate the risks associated with HOT, particularly among those who continue to smoke. Further research is warranted to develop and implement effective interventions to improve outcomes for this vulnerable patient population.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pirfenidone ameliorates hypertrophic scar through inhibiting proliferation and migration of fibroblasts by regulating the Wnt/GSK-3β/β-catenin signaling pathway. 吡非尼酮通过调节Wnt/GSK-3β/β-catenin信号通路抑制成纤维细胞增殖和迁移，改善增生性瘢痕。

IF 1.5 4区医学

Journal of Burn Care & Research Pub Date : 2025-04-08 DOI: 10.1093/jbcr/iraf040

ZhengHao Dai, YiWen Jiang, Hang Guo, YuTing Lu, WeiGuo Chen, Tao Liang

{"title":"Pirfenidone ameliorates hypertrophic scar through inhibiting proliferation and migration of fibroblasts by regulating the Wnt/GSK-3β/β-catenin signaling pathway.","authors":"ZhengHao Dai, YiWen Jiang, Hang Guo, YuTing Lu, WeiGuo Chen, Tao Liang","doi":"10.1093/jbcr/iraf040","DOIUrl":"https://doi.org/10.1093/jbcr/iraf040","url":null,"abstract":"Hypertrophic scar (HS) is a prevalent complication that arises from burn injuries. While Pirfenidone (PFD) is known to be an effective antifibrotic agent, its precise effects on HS caused by burn injuries are still unclear. This study was to assess the influence of PFD on HS fibroblasts and investigate the underlying mechanism. HS tissue and normal skin tissue samples were collected, and fibroblasts were isolated from HS tissues and normal skin. The cytotoxic effect was detected by lactate dehydrogenase (LDH). Cell proliferation was detected by CCK-8 and EdU methods, and migration was detected by Transwell. Transforming growth factor β1 (TGF-β1), α-smooth muscle actin (α-SMA), and type I collagen (COL-I) mRNA expression levels were analyzed by RT-qPCR. TGF-β1, α-SMA, COL-I, and APC protein expression levels, as well as phosphorylation of GSK-3β and β-catenin were detected by Western blot. The results indicated that PFD inhibited the proliferation of HS fibroblasts without cytotoxicity. PFD inhibited the migration of HS fibroblasts and differentiation by inhibiting TGF-β1, α-SMA, and Col-I expression. PFD reduced the phosphorylation of GSK-3β and β-catenin, suppressed APC protein expression, and blocked the Wnt/GSK-3β/β-catenin cascade. PFD can ameliorate HS after burn injuries and inhibit proliferation and differentiation of HS fibroblasts through the Wnt/GSK-3β/β-catenin cascade.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143972795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of Health-Related Quality of Life in post-burn Adult Survivors: A Cross-sectional Four Years of Experience Study from Cyprus. 烧伤后成年幸存者健康相关生活质量评估：来自塞浦路斯的四年横断面经验研究

IF 1.5 4区医学

Journal of Burn Care & Research Pub Date : 2025-03-28 DOI: 10.1093/jbcr/irae213

Ilias Petrou, Athanasios Papas, Georgina Panopoulou, Andreas Vassiliou

{"title":"Assessment of Health-Related Quality of Life in post-burn Adult Survivors: A Cross-sectional Four Years of Experience Study from Cyprus.","authors":"Ilias Petrou, Athanasios Papas, Georgina Panopoulou, Andreas Vassiliou","doi":"10.1093/jbcr/irae213","DOIUrl":"https://doi.org/10.1093/jbcr/irae213","url":null,"abstract":"Burn injuries have a significant impact on various aspects of survivors' lives. This study evaluates, assesses, and interprets the health-related quality of life in post-burn adult survivors. Of 135 patients admitted from 2019 to 2023 in the burns intensive care unit, 70 responded to a questionnaire. Primary socio-demographic data and details about the cause and extent of burns were collected. A brief (EuroQol-5 Dimension-5 Levels) EQ-5D-5L questionnaire was completed by interviewing burn survivors, and data were then analysed. The mean age of participants was 52.12 years, and the prevalent gender was males (61.4%). Thermal burns were the most common cause of burn-related injury (91.4%)-most subjects (57.1%) suffered from partial-thickness burns, followed by full-thickness burns affecting 40.0%. The most presented percentage of Total Body Surface Area (%TBSA) burned was 1-10%, accounting for 60% of cases. The most required hospitalization timeframe was 1-5 days. Regarding participants' Quality of Life (QoL), most reported no problem in the five health dimensions. The health dimensions that were mainly affected were depression/anxiety followed by pain/discomfort. All participants' mean EQ-Visual Analogue Scale (EQ-VAS) score was 80.98. Our findings disclose a compromised health-related quality of life for post-burn individuals, particularly in dimensions of depression/anxiety followed by pain/discomfort. There is a pressing need to establish long-term support for burn survivors by relevant organisations.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characteristics of Verified and Designated Burn Centers. 认证和指定烧伤中心的特点。

IF 1.5 4区医学

Journal of Burn Care & Research Pub Date : 2025-03-24 DOI: 10.1093/jbcr/iraf035

Anastasiya Ivanko, Elle Lovick, M Victoria P Miles, Denise Danos, Jonathan E Schoen, Randy Kearns, Bart Phillips, Erica Murata, John B Holcomb, Herb A Phelan, Jeffrey E Carter

{"title":"Characteristics of Verified and Designated Burn Centers.","authors":"Anastasiya Ivanko, Elle Lovick, M Victoria P Miles, Denise Danos, Jonathan E Schoen, Randy Kearns, Bart Phillips, Erica Murata, John B Holcomb, Herb A Phelan, Jeffrey E Carter","doi":"10.1093/jbcr/iraf035","DOIUrl":"https://doi.org/10.1093/jbcr/iraf035","url":null,"abstract":"Burn Center (BC) verification is a rigorous process designed to ensure optimal care for burn injury patients. The American Burn Association (ABA) lists 135 verification criteria, yet only 50-60% of BCs are verified. This study assesses the operational, financial, and clinical disparities between verified burn centers (VBCs) and non-verified burn centers (nVBCs) in the U.S. the U.S. The study was conducted using The Databases for Optimal Resources for Injury Care (DORIC), a centralized database developed from the American Hospital Association (AHA), American College of Surgeons Committee on Trauma, ABA, all fifty United States' (U.S.) Departments of Health, the National Injury Resource Database (NIRD), and claims databases, through collaboration with BData, Louisiana State University Health Sciences Center (LSUHSC), and University of New Orleans (UNO). Data were analyzed for quality and statistical rigor by a data analyst and a biostatistician. The study demonstrated no significant differences in hospital size, location (urban/rural), hospital bed number, or burn intensive care unit bed number between VBCs and nVBCs. However, significant differences were identified in total hospital discharges and revenue. VBCs had more patient discharges (median 22,212 vs. 15,639; p=0.019) and generated significantly more total revenue (median $994,945,750 vs. $652,390,948; p=0.014), Medicare revenue (median $171,016,940 vs. $83,739,527; p=0.0023), and inpatient revenue (median $2,070,789,977 vs. $1,347,440,093; p=0.0125) compared to nVBCs. These disparities in discharges and revenue underline the financial and operational benefits of BC verification. Our findings provide valuable insights to guide policy and decision-making in burn care, aiming to improve care quality, accessibility, and equity.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Safety of Maintaining Nutrition Through Moderate Sedation for Burn Wound Care. 通过适度镇静维持烧伤创面营养的安全性。

IF 1.5 4区医学

Journal of Burn Care & Research Pub Date : 2025-03-23 DOI: 10.1093/jbcr/iraf033

Amber D Kohler, Scott W Mueller, Naveen Kukreja, Thomas Orion Vogler, Blaire Balstad, Frederick W Endorf, Cameron Gibson, Alexandra E Halevi, Arek J Wiktor

{"title":"Safety of Maintaining Nutrition Through Moderate Sedation for Burn Wound Care.","authors":"Amber D Kohler, Scott W Mueller, Naveen Kukreja, Thomas Orion Vogler, Blaire Balstad, Frederick W Endorf, Cameron Gibson, Alexandra E Halevi, Arek J Wiktor","doi":"10.1093/jbcr/iraf033","DOIUrl":"https://doi.org/10.1093/jbcr/iraf033","url":null,"abstract":"Burn patients often require frequent moderate sedation for burn wound care procedures. The American Society of Anesthesiology recommends patients be made nil per os prior to moderate sedation. Here, we aimed to assess the risk of moderate sedation in burn patients with uninterrupted nutrition. A 12-month single-center retrospective analysis on non-intubated/non-tracheostomy burn patients receiving moderate sedation for wound care was performed. A total of 97 moderate sedations were completed on 24 patients. A median of three oral premedications and three intravenous analgesic/anxiolysis medications per patient were administered during each periprocedural period and achieved a median Richmond Agitation-Sedation Score of -2 (-3, -1). The median of any kind of nutrition was consumed 38 minutes prior to sedations, with a median of 113 minutes from consumption of a full meal. In 32 sedations (33%), patients had tube feeds continued throughout wound care. No complications related to aspiration were noted in any sedation event (97.5% upper Confidence Interval 3.7%), including no episodes of vomiting, evidence of aspiration, pneumonia, hypoxemia, complete airway obstruction, laryngospasm, or death. Hypertension was noted in 17 sedations. Hypotension was noted in six sedations. In conclusion, no harmful adverse events were associated with maintained nutrition throughout the peri- and intra-sedative wound care periods, including ongoing gastric tube feeds in this small sample of burn patients. These data suggest that uninterrupted nutrition during burn wound care moderate sedation procedures is a safe practice and warrants further study.","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0