Ayana K Cole-Price, Elizabeth Silverman, Peter Sienko, Heather Molvik, Gary A Vercruysse
{"title":"An Initial Report of Thermal Runaway Resulting in Full-Thickness Foot Burns From Lithium-Ion Battery-Powered Insole.","authors":"Ayana K Cole-Price, Elizabeth Silverman, Peter Sienko, Heather Molvik, Gary A Vercruysse","doi":"10.1093/jbcr/irae157","DOIUrl":"10.1093/jbcr/irae157","url":null,"abstract":"<p><p>Lithium-ion batteries are used in many commercial products such as electronics, cell phones, and e-cigarettes. The use of these batteries has become widespread over recent years due to their chargeability and long-lasting performance. Though a rare occurrence, lithium-ion batteries can fail due to myriad battery defects, which can cause fires and burns. One particular concern is that of thermal runaway, a critical failure marked by a sudden exothermic reaction that occurs as a result of damage to the lithium battery. Thermal runaway can produce heat in excess of 1800 °F, causing severe burns to individuals in close proximity. A 39-year-old man presented to an emergency department (ED) with full-thickness burns to his right foot after an episode of lithium-ion battery thermal runaway in his footwarmer. The patient's boot suddenly and unexpectedly caught fire for several seconds prior to being successfully removed. The patient subsequently underwent several weeks of debridements, auto- and homografting, and wound care before eventually making a full recovery. This case highlights the rare, but serious, risk posed by lithium-ion batteries as a result of thermal runaway. This phenomenon can cause devastating full-thickness burns in a matter of seconds. As lithium-ion-powered appliances grow in popularity, stringent safety measures should be implemented to prevent catastrophic injuries. Furthermore, healthcare providers should be made aware of injuries caused by thermal runaway to appropriately treat patients.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"1636-1640"},"PeriodicalIF":1.5,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141912841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammed Fuad Alrasheed, Hamad Alkhalaf, Alhanouf Mohammed Alqahtani, Afnan Saad Alzubaidi, Abdulrahman Ali Alasmari, Dalal Owith Al-Osimi, Loai Hasan Bahkali, Anoud Mohammed Alholais, Noor Ibraheem Basheikh, Atheer Mohammed Althaqafi, Nourah Mansour Almousa, Fatimah Hassan Al Mazrou, Amal Abdulhameed Alsadiq, Yasser M Kazzaz
{"title":"The Epidemiology of Pediatric Thermal Injury-associated Toxic Shock Syndrome: A Systematic Review.","authors":"Mohammed Fuad Alrasheed, Hamad Alkhalaf, Alhanouf Mohammed Alqahtani, Afnan Saad Alzubaidi, Abdulrahman Ali Alasmari, Dalal Owith Al-Osimi, Loai Hasan Bahkali, Anoud Mohammed Alholais, Noor Ibraheem Basheikh, Atheer Mohammed Althaqafi, Nourah Mansour Almousa, Fatimah Hassan Al Mazrou, Amal Abdulhameed Alsadiq, Yasser M Kazzaz","doi":"10.1093/jbcr/irae141","DOIUrl":"10.1093/jbcr/irae141","url":null,"abstract":"<p><p>Thermal injury-associated toxic shock syndrome (TSS) is a life-threatening condition that can occur in children following burn injuries. The objective of this study was to describe the clinical manifestations, treatment, and outcomes of children who experienced TSS following a thermal injury. Additionally, the existing literature was systematically examined and published cases of pediatric TSS occurring after burns were compiled. In June 2023, without regard for time constraints, articles that met the criteria were searched across several electronic databases. The inclusion criteria were English-language publications, pediatric patients, and reported outcomes of interest for clinical questions. Due to the heterogeneity of the included publications and the lack of data in an appropriate format, a meta-analysis was not feasible. Our research identified 23 studies published between 1980 and 2023, including 72 cases (from multiple countries) that met the inclusion criteria. Of the 72 patients with thermal injuries complicated by TSS, 53 (73.6%) children survived, 6 (8.3%) died, and for 13 (18%) cases, the outcome was not documented. Our systematic review highlights the rarity, severity, and complexity of pediatric thermal injury-associated TSS. Key findings from the review indicate that pediatric thermal injury-associated TSS carries a high mortality rate and significant morbidity. By increasing awareness, improving diagnostic accuracy, and optimizing treatment strategies, healthcare professionals can improve patient outcomes in this challenging condition.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"1627-1635"},"PeriodicalIF":1.5,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141748271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Din Mann, Nurit Bar-Shai, Klimentiy Levkov, Batel Gabay, Edward Vitkin, Abraham Nyska, Martin Yarmush, Avshalom Shalom, Alexander Golberg
{"title":"Treating Scars After Burns With Pulsed Electric Fields in the Rat Model.","authors":"Din Mann, Nurit Bar-Shai, Klimentiy Levkov, Batel Gabay, Edward Vitkin, Abraham Nyska, Martin Yarmush, Avshalom Shalom, Alexander Golberg","doi":"10.1093/jbcr/irae154","DOIUrl":"10.1093/jbcr/irae154","url":null,"abstract":"<p><p>Reducing scar size after severe burn injuries is an important and challenging medical, technological, and social problem. We have developed a battery-powered pulsed electric field (PEF) device and surface needle electrode applicator to deliver PEFs to the healing dorsal burn wound in rats. The pulsed electric field was used to treat residual burn wounds caused by metal contact in rats starting 10 days after the injury for 4 months every 11 or 22 days for 4 months using varying time applied voltages at 250-350 V range, 400 mA current, 40 pulses, 70 μs duration each, delivered at pulse repetition frequency 10 Hz at 5 locations inside the wound. We found 40%-45% reduction in the scar size in comparison with untreated controls in both upper and lower dorsal locations on rats' backs 2 months after the last PEF application. We have not detected significant histopathological differences in the center of the scars besides the thickness of the newly generated epidermis, which was thicker in the PEF-treated group. We showed that minimally invasively applied PEFs through needle electrodes are effective method and device for treating residual burn wounds in the rat model, reducing the size of the resulting scars, without any adverse reaction.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"1553-1565"},"PeriodicalIF":1.5,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141897532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clint Leonard, Matthew Sigel, Anne Wagner, Richelle Jones, Denise Hargis, Maria Troche, Elizabeth Dale Slater
{"title":"Increasing Discharges Prior to 11am in Patients with Burn Injuries.","authors":"Clint Leonard, Matthew Sigel, Anne Wagner, Richelle Jones, Denise Hargis, Maria Troche, Elizabeth Dale Slater","doi":"10.1093/jbcr/irae200","DOIUrl":"10.1093/jbcr/irae200","url":null,"abstract":"","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stephanie Chang, Aldin Malkoc, Jaclyn R Cerceo, Amanda Daoud, David T Wong
{"title":"Quality of Life Assessment Four Years after a More than Ninety Percent Total Body Surface Area in Two Survivors with Burns: Case Report.","authors":"Stephanie Chang, Aldin Malkoc, Jaclyn R Cerceo, Amanda Daoud, David T Wong","doi":"10.1093/jbcr/irae202","DOIUrl":"10.1093/jbcr/irae202","url":null,"abstract":"<p><p>There are few reports in the literature detailing the Quality of Life (QOL) of survivors with greater than 90% total body surface area (TBSA) burns. The objective was to assess two such individuals seen at our center with the Burn Specific Health Scale-Brief (BSHS-B) survey four years after discharge. Subject responses were categorized into their respective BSHS-B health domains (heat sensitivity, affect, hand function, treatment regimens, work, sexuality, interpersonal relationships, simple abilities, and body image) and a raw score was calculated for each domain. Lower scores indicated a greater perceived decrease in QOL. The nine domains of BSHS-B survey questions were further separated into three categories: physical (hand function, work, simple abilities), treatment (treatment regimens and heat sensitivity), and psychosocial (interpersonal relationships, affect, body image, sexuality). The psychosocial category had higher scores and better outcomes, while the physical and treatment ones had lower scores and worse outcomes compared to the other categories. For both individuals, interpersonal relationships and simple tasks domains were considered important in their QOL, while work, heat sensitivity and hand function received lower scores. Family support, intense physical rehabilitation, and psychosocial management were crucial during the postoperative and follow-up periods.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142590778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Metabolomic analysis of HUVEC after Thermal denaturation UHPLC-MS/MS-based metabolomics.","authors":"Fangqin Wu, Zhuoxian Yan, Yanqin Ran, Mengna Wang, Sifan Yang, Mitao Huang, Situo Zhou, Pihong Zhang, Pengfei Liang, Bimei Jiang","doi":"10.1093/jbcr/irae162","DOIUrl":"https://doi.org/10.1093/jbcr/irae162","url":null,"abstract":"<p><p>Preserving denatured dermis has been shown to promote wound healing and improve skin appearance and function. Angiogenesis is crucial for the healing of burn wounds. However, the metabolic mechanisms underlying angiogenesis during burn recovery remain unclear. In this study, ultra-high performance liquid chromatography-mass spectrometry analysis revealed six distinct metabolites in a heat-denatured cell model. A bioinformatics approach was used to predict the differentially expressed metabolites, and four metabolic pathways closely related to trauma repair were identified. These pathways might play a significant role in the regression of thermally injured endothelial cells. We also found that increasing D-mannose level promoted the angiogenic activity of human umbilical vein endothelial cells in the heat-denatured cell model, enhancing cell proliferation, migration, and tube formation. In summary, these findings revealed changes in metabolites and metabolic pathways in thermally injured endothelial cells, and demonstrated that D-mannose could promote angiogenesis during the recovery of thermally injured endothelial cells.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142575933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk Factors for ARDS in Hospitalized Burn Patients: An Analysis of the National Trauma Data Bank.","authors":"Danielle Sim, Madhu Subramanian, Julie Caffrey","doi":"10.1093/jbcr/irae199","DOIUrl":"https://doi.org/10.1093/jbcr/irae199","url":null,"abstract":"<p><p>Acute Respiratory Distress Syndrome (ARDS) is a common complication among mechanically ventilated adult burn patients; however, the risk factors associated with its development are not well understood. Conflicting evidence also exists regarding ARDS as an independent predictor of poor hospital outcomes. The purpose of this study is to identify risk factors for ARDS in mechanically ventilated adult burn patients and characterize the impact of ARDS on hospital course. The National Trauma Data Bank (NTDB) was queried for patients >=18 years with International Classification of Diseases (ICD) codes corresponding to burn injury from 2007-2016. Hospitalized patients with at least 48 hours of mechanical ventilation were included. Multivariate logistic regression were used to identify risk factors for ARDS. Propensity score-matched analysis at a 1:3 ratio was used to determine the impact of ARDS on hospital course. This sample included 13928 patients, of which 1437 (10.3%) developed ARDS. Hypotension in the Emergency Department, alcohol use disorder, total body surface area (TBSA), Injury Severity Score (ISS), and inhalation injury were independently associated with ARDS. In the propensity score-matched cohort, ARDS patients had a significantly longer median (interquartile range) length of stay (31 [15-54] vs. 22 [9-43], p<0.001). In-hospital mortality was also significantly higher in the ARDS cohort (203 [35%] vs. 325 [24%], p<0.001). These findings highlight the impact of patient and injury characteristics on developing ARDS and support the consideration of ARDS when estimating mortality risk in burn patients.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142557908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Impact of Individual Cognitive Stimulation Therapy on Caregivers of Burn Patients.","authors":"Cuina Zhang, Beibei Qin, Guihua Zhang, Jianke Feng, Wei Wei, Haitao Li, Liang Xing","doi":"10.1093/jbcr/irae197","DOIUrl":"https://doi.org/10.1093/jbcr/irae197","url":null,"abstract":"<p><p>This study aimed to investigate the effects of Individual Cognitive Stimulation Therapy (ICST) on the cognition, quality of life, and family relationships of caregivers of burn patients. A total of 98 caregivers of burn patients were randomly divided into a control group and a study group. The control group received routine interventions, while the study group underwent ICST, focusing on psychological diagnosis, comprehension, communication, and re-education phases. Burn awareness levels, quality of life, social support utilization, and psychological resilience were assessed before and after the intervention. Before intervention, there were no significant differences in burn awareness levels, quality of life, social support utilization, or psychological resilience between the two groups. After the intervention, caregivers in the study group exhibited significantly higher scores in burn awareness levels, quality of life dimensions, social support utilization, and psychological resilience compared to the control group (P < 0.05). Individual Cognitive Stimulation Therapy can improve the burn awareness level, quality of life, and social support utilization of caregivers of burn patients, highlighting its significant clinical implications in enhancing caregiver well-being and patient care.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yoram Shoham, Paul Comish, Rotem Tsur, Eldad Silberstein, Yuval Krieger, Tal Eliav, Michelle Cleary, Rachel Kornhaber, Jeremy Goverman
{"title":"Topical steroid use for suppression of hypergranulation in burns: Trends across the Atlantic.","authors":"Yoram Shoham, Paul Comish, Rotem Tsur, Eldad Silberstein, Yuval Krieger, Tal Eliav, Michelle Cleary, Rachel Kornhaber, Jeremy Goverman","doi":"10.1093/jbcr/irae191","DOIUrl":"https://doi.org/10.1093/jbcr/irae191","url":null,"abstract":"<p><p>Hypergranulated wounds from thermal injury remain a complex and debilitating problem for burn patients. Currently, there is no standard therapy to prevent or treat hypergranulation following burn injury. Many centers use topical corticosteroids; however, their use seems to be geographically dependent and controversial. The primary aim of this study was to quantify the current use of topical corticosteroids for post-burn hypergranulation in North America (NA) and Europe, while secondarily assessing for perceptions of safety and efficacy. We designed a survey that was distributed to the members of the European and American Burn Associations. Data was extracted and analyzed using SPSS software. A total of 165 respondents completed the survey (90 and 75 for the European and NA members, respectively). Seventy-one of the 90 (78.9%) European respondents reported they routinely use topical steroids for suppression of hypergranulation tissue in burns, versus 25 of the 75 (33.3%) NA respondents (p<0.001). European respondents, compared to NA respondents, were significantly more likely to consider topical steroid use safe (100% vs. 74.4%, p <0.001) and effective (98.6% vs. 66.7%, p < 0.001) for treatment of hypergranulated burn wounds. There was no significant difference in reported systemic effects seen after topical steroid use when comparing NA respondents and European respondents (6.5% vs. 6.9%, p > 0.10). The results of this study suggest that the use of steroids for hypergranulation tissue in burn care is more prevalent in Europe than NA, which may be due to discordant views on safety and efficacy despite minimal reported adverse effects.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Callie M Thompson, Amy Acton, William Alexander, Robel Beyene, Elisha G Brownson, Gretchen J Carrougher, Brennan Christensen, Kimberly Hoarle, Jessica Irven, Laura S Johnson, Monica P Kirkham, Giavonni M Lewis, J Xavier Lucio, Samoana Matagi, Laura Morris, Ann Marie B Prazak, Erin Price-Smith, Bridget Stuchly, Crystal Webb, Kristen Quinn
{"title":"Engaging Burn Survivors, Their Families, and the Burn Community in Patient-Centered Outcomes Research: A Burn Survivor- and Burn Community Stakeholder-Generated and Prioritized Research Agenda.","authors":"Callie M Thompson, Amy Acton, William Alexander, Robel Beyene, Elisha G Brownson, Gretchen J Carrougher, Brennan Christensen, Kimberly Hoarle, Jessica Irven, Laura S Johnson, Monica P Kirkham, Giavonni M Lewis, J Xavier Lucio, Samoana Matagi, Laura Morris, Ann Marie B Prazak, Erin Price-Smith, Bridget Stuchly, Crystal Webb, Kristen Quinn","doi":"10.1093/jbcr/irae196","DOIUrl":"https://doi.org/10.1093/jbcr/irae196","url":null,"abstract":"<p><p>Burn survivors are involved in burn research, but typically in the role of research subject. We believe that the outcomes and impact of burn research can be improved by engaging survivors as collaborators in the planning, implementation, and dissemination of burn research. The goal of this work was to produce the first burn research agenda generated and prioritized by burn survivors and other stakeholders from the burn community. A series of structured focus groups covering five topics (Patient and Family Education, Aftercare, Navigating the Healthcare System, Recovery: Physical and Psychosocial, and Barriers to Research) were held with burn survivors and their family members. Specific research questions/topics were identified from the transcripts and prioritized via an anonymous survey of burn survivors, their caregivers, and other stakeholders from the burn community. From these sessions, 37 specific research questions/topics were identified and ranked. In addition, 19 research barriers were identified and ranked. This work presents an innovative approach to burn research through co-production with survivors and other stakeholders. Burn survivors and their caregivers are experts in their lived experiences. By involving them in burn research as collaborators and contributors from the very first steps of research and throughout the continuum of the research planning, conducting projects, and distributing findings, we believe that the research will be both more successful and more impactful. We have taken the first steps in burn research co-production with this novel stakeholder-generated research agenda for the burn community.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142501088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}