Journal of Burn Care & Research最新文献

{"title":"Burn Progression in Human Skin-A Review of Current Knowledge and Opportunities for Future Research.","authors":"Mary Junak, Angela Gibson","doi":"10.1093/jbcr/iraf014","DOIUrl":"10.1093/jbcr/iraf014","url":null,"abstract":"<p><p>Treatment of a burn wound often depends on the vertical depth of injury, which is commonly determined by visual assessment. Burn progression is the concept that in the early postburn period, a partial-thickness burn may progress to a deeper burn requiring surgery. Therefore, the initial appearance of the wound may not be indicative of the eventual extent of injury. Several preclinical studies attribute burn wound progression to events such as vasoconstriction, inflammation, programmed cell death, free radical damage, and microvascular occlusion. Due to the concern for translatability of animal models for burn wounds, human studies are essential to understanding burn progression in patients. Unfortunately, only a few small human studies exploring mechanisms including apoptosis, ischemia, and infection exist. Inherent to determining burn progression is burn-depth determination and healing potential, an area of research that has many ongoing investigations without a clear standard method to replace visual evaluation. Treatments to prevent burn progression in humans, including the use of negative pressure wound therapy and the application of cooling dressings, have been studied with small sample sizes. Here, we aim to summarize the current data on human burn progression. In addition, we discuss novel methods that could be used in future research to define early burn wound progression. Future work in human tissue should focus on the assessment and timeline of progression, explore the reversibility and prevention of injury progression and use animal models in parallel as complementary tools for hypothesis-driven research based on findings in humans.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"758-767"},"PeriodicalIF":1.8,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143433231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lessons Learned Evaluating Ablative Fractional CO2 Laser for Burn-Related Donor Site Scars.","authors":"Cameron S D'Orio, Bonnie C Carney, Jasmine H Wong, Angela Golding, Alison Ross, Melissa M McLawhorn, Rebekah R Allely, Jeffrey W Shupp, Shawn Tejiram, Taryn E Travis","doi":"10.1093/jbcr/iraf030","DOIUrl":"10.1093/jbcr/iraf030","url":null,"abstract":"&lt;p&gt;&lt;p&gt;Hypertrophic scar (HTS) remains a comorbidity of burn injury, often requiring split-thickness skin grafting (STSG) and resulting in symptomatic HTS at grafted sites and STSG donor sites (DS). Literature supports the use of ablative fractional CO2 laser (FLSR) to treat HTS, however many trials lack control sites and tissue-level examinations. Given the widespread adoption of FLSR for HTS, delegation of non-treated scar sites for the sake of randomized controlled trials (RCT) is troubling for many clinicians. We trialed using STSG DS scars for randomization rather than withholding FLSR from HTS at grafted sites. Patients (n = 20) were treated for DS scar with FLSR. DS scars were randomized and treated with either 6 FLSR treatments, follow-ups, and standard of care (SOC) or SOC only. Prior to treatment, DS skin and normal skin (NS) were evaluated for trans-epidermal water loss (TEWL), melanin index (MI), elasticity, and erythema. Serial biopsies were analyzed for epidermal thickness, rete ridge ratio (RRR), and papillary dermal cellularity. All sites, including a separate burn scar (BS) site, were evaluated using the patient and observer scar assessment scale (POSAS) -observer (-O), -patient (-P), Vancouver Scar Scale (VSS), and an institutional Scar Comparison Scale (SCS). Prior to treatment, the DS control (DS C), DS treated (DS T), and BS sites were hyperpigmented compared to normal skin. BS was less elastic than all other sites and had increased TEWL compared to normal skin. DS skin had increased cellularity, decreased rete ridge ratios, and increased epidermal thickness compared to NS. Clinician observers and patients perceived the BS site as more severe versus DS skin through the POSAS-O, POSAS-P, and VSS. Over time, DS C and DS T sites were not different in TEWL, elasticity, erythema, MI, cellularity, RRR, epidermal thickness, POSAS-O scores, POSAS-P scores, VSS scores, or SCS scores. Over time, burn scar did not change in TEWL, elasticity, erythema, MI, POSAS-O scores, POSAS-P scores, and VSS scores. Decreased SCS scores within the DS C, DS T, and BS sites indicated patient-perceived improvement in all scars throughout the study time course. NS and DS skin possess inherent physiological differences, though not to the degree of burn scars vs. NS. FLSR may not alter the rate of maturation and remodeling of DS skin compared to current SOC. While improvement in scar assessment was observed in laser-treated BS HTS, no specific control for these sites was analyzed. Due to differences in the pathophysiology of HTS formation at grafted and donor sites, the STSG DS may not be an adequate substitute for BS HTS when designing RCTs to evaluate the effect of FLSR. Prior studies evaluating the use of FLSR in burn-related HTS consist of low-powered clinical trials or case studies without control sites or tissue-level examinations, prompting the design of an RCT in DS scars. However, this scar type may not be suitable for this study design. Future wor","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"708-724"},"PeriodicalIF":1.8,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing Mechanisms of p38MAPK/NF-κB in Regulating Postdebridement Inflammatory Response during the Shock Period in Burned Rats.","authors":"Jin-Li Zhang, De-Yun Wang, Wei-Guo Xie","doi":"10.1093/jbcr/iraf028","DOIUrl":"10.1093/jbcr/iraf028","url":null,"abstract":"<p><p>This study aimed to observe the temporal changes in inflammatory factors and explore the mechanisms regulating inflammation during the shock period following debridement in rats. A burn model was established in SD rats using a 30% total body surface area III-degree scald. Rats were divided into 3 groups: control group, debridement group (12 h postburn debridement with heterograft skin coverage), and sham surgery group (simulated debridement with autograft skin coverage). Serum samples were collected at 12, 24, 48, 72, and 96 h postinjury to assess levels of inflammatory factors and proteins related to the p38 MAPK/NF-κB pathway. The levels of lipopolysaccharide-binding protein (LBP), high-mobility group box 1 (HMGB1), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and IL-10 in the control group peaked between 12 and 48 h postinjury, while HMGB1 increased gradually, peaking at 96 h. Compared to the control group, both the debridement and sham surgery groups showed significant reductions in these inflammatory factors (P < 0.01 or P < 0.05), except for LBP. Liver p38MAPK levels showed no significant difference between groups, but phosphorylated p38MAPK and NF-κB levels significantly decreased (P < 0.05 or P < 0.01). In the debridement group, intragroup comparisons revealed a significant downward trend in inflammatory factors and liver p38MAPK and NF-κB phosphorylation levels. These results suggest that debridement during the shock period can reduce inflammation through the p38MAPK/NF-κB pathway, promoting a faster decline in systemic inflammatory response.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"809-817"},"PeriodicalIF":1.8,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development for the Teen-Aged Life Impact Burn Recovery Evaluation (TA-LIBRE12-19) Profile.","authors":"Khushbu F Patel, Madeleine B McGwin, Mary D Slavin, Kate E Surette, Jeffrey C Schneider, J Michael Murphy, Frederick J Stoddard, Lewis E Kazis, Colleen M Ryan","doi":"10.1093/jbcr/iraf058","DOIUrl":"10.1093/jbcr/iraf058","url":null,"abstract":"<p><p>Advances in clinical burn management have led to emphasis on using assessments in clinics. Outcome measures are important to assess the effectiveness of interventions, and support integration back into the community. A more granular measure with advanced psychometrics capability using Computerized Adaptive Testing (CAT) is needed. The current study developed a conceptual model as the first step in creating a new measurement tool for teen burn survivors aged 12-19 years, inclusively. To identify outcomes important in assessment of burn recovery, focus groups of clinicians, teens, and their parents were conducted until thematic saturation was reached. Each focus group transcript was analyzed using deductive and inductive approaches to identify and categorize content. Findings were used to validate the model and ensure adequate domain coverage. The Teen-Aged Life Impact Burn Recovery Evaluation (TA-LIBRE12-19) conceptual model includes Activity (Mobility, Physical Self-care, General Tasks, Experience of Self, and Learning and Applying Knowledge) and Participation (Major Life Areas, Interpersonal Interactions and Relationships, and Engagement). Eighteen participants completed the study. Clinician's median age was 47 years (90% female and 80% White); teens' median age was 14 years (62% female and 75% White). Burn size ranged from 0.25% to 60% TBSA. Focus group content was coded a total of 1,138 times during the analysis. Outcome areas most impacted include Experience of Self, Interpersonal Interactions and Relationships, and Symptoms (372, 282, and 112 codes, respectively). A well-informed credible conceptual model was developed with a solid foundation of domains consisting of Activity and Participation.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"894-902"},"PeriodicalIF":1.8,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12353382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143997969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Silver Sulfadiazine and Boric Acid are Effective in Protecting the Stasis Zone from Secondary Ischemia.","authors":"Muhammed Salih Süer, Ömer Cennet, Mehmet Ülkir, Elham Bahador Zirh, Ayşegül Fırat, Ali Konan","doi":"10.1093/jbcr/iraf068","DOIUrl":"10.1093/jbcr/iraf068","url":null,"abstract":"<p><p>A burn wound is characterized by hyperemia on the outer layer, stasis in the middle zone, and coagulation zones in the innermost region due to thermal damage to the skin. It is crucial to provide prompt and adequate treatment to prevent further damage. The depth of the burn increases as ischemic indicators become more distinct in the stasis zone when the burn is not adequately treated, despite the absence of ischemic signs in the stasis zone at the initial stages of the wound. This study aims to assess the impact of silver sulfadiazine, boric acid, low-molecular-weight heparin, and glyceryl trinitrate on wound healing in the stasis zone. The study involved 4 intervention groups, each consisting of 6 rats, and a sham group. After 7 days of daily topical application of the active substances, the animals were sacrificed, and wound healing in the stasis zones was evaluated through macroscopic, histological, and immunohistochemical analysis. These findings demonstrate the effectiveness of these treatments in promoting wound healing. The results demonstrated that the boric acid and silver sulfadiazine groups exhibited the highest levels of wound healing, both macroscopically and histologically. Immunohistochemistry revealed significant differences, with the silver sulfadiazine group demonstrating superior results in MMP9 staining and the boric acid group in VEGF staining (P < .05). These findings suggest that boric acid and silver sulfadiazine effectively prevent ischemia in the stasis zone. Boric acid, in particular, appears to have significant potential as a wound-healing agent due to its anti-inflammatory properties.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"909-916"},"PeriodicalIF":1.8,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Decrease in Total Leukocyte Count is Associated with Acute Kidney Injury After Severe Burn.","authors":"Julie A Rizzo, Jason M Thomas, James K Aden, Steven G Schauer, Jan-Michael Van Gent, Wylan C Peterson, Luke J Hoffman, Jose Salinas, Laura S Johnson","doi":"10.1093/jbcr/iraf039","DOIUrl":"10.1093/jbcr/iraf039","url":null,"abstract":"<p><p>Leukocytosis is common after burn injury from profound systemic inflammatory response. Total leukocyte count (TLC) often decreases 72-96 h post-injury. The incidence of early (<72 h) leukopenia has not been previously described; this analysis sought to determine if early and extreme decreases in TLC were associated with increased fluid requirements or resuscitation-related outcomes in patients after burn injury. The burn navigator (BN) database is composed of 300 patients with >20% TBSA and >40 kg that were resuscitated utilizing the BN clinical decision support system. Patients were split into 2 groups based on a decrease in TLC from admission of greater than versus less than 15 000 cells per microliter. Demographics, resuscitation volumes, resuscitation-related complications, and 7-day survival were collected. Of the 295 patients in the analysis, patients with greater than the 15-point decrease in WBC from admission had more full-thickness burns (14.2 [2, 36]) and greater TBSA (41 [30.2, 57.4]) than those with less than a 15-point decrease (7.7 [0.3, 14.8], P < .001), 27.5 [23, 36], P < .001. Patients with greater than a 15-point WBC drop had a significantly higher incidence of admission myoglobinuria and AKI in the first 48 h even after adjusting for TBSA. Survival at 7 days did not differ (66.7% vs. 83.7%, P > .05) when adjusting for TBSA. A decrease in WBC of at least 15 points after admission was associated with early AKI and a significantly higher incidence of admission myoglobinuria. Future studies need to investigate the mechanism behind this association and possible early interventions.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"850-853"},"PeriodicalIF":1.8,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parental Acute Distress During Initial Ambulatory Pediatric Burn Clinic Visit.","authors":"Carrie Tully, Nakisa Asefnia, Aaron Mun","doi":"10.1093/jbcr/iraf032","DOIUrl":"10.1093/jbcr/iraf032","url":null,"abstract":"<p><p>Burn injuries in children are a significant source of distress for both the child and their parents. Beyond the acute distress of the injury itself and its subsequent treatment course, families can develop larger psychological symptoms such as anxiety, depression, and posttraumatic stress symptoms. Parental distress can influence the child's response to pain, and in turn, their injury recovery. Identifying temporal patterns of distress during the treatment course is crucial to providing early and effectively timed psychological interventions. This study explores the relationship between parental distress at three key time points-before, during, and at the end of the child's initial burn clinic visit-with psychosocial outcomes. Findings support a dynamic relationship between parental distress, child acute stress symptoms, and child-observed pain during the initial burn clinic visit, underlining the importance of parental distress in the child's recovery. Future work should focus on developing resilience-based, family-centered interventions to improve the quality of care and long-term psychosocial outcomes.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"833-838"},"PeriodicalIF":1.8,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Process to add Long-Term Outcomes into the American Burn Association's Burn Registry - Feasibility to Bridge the Gap.","authors":"Claudia C Malic, Thereasa Abrams, Adam J Singer, Joan Webber, Heidi Altamirano, Farrah Parker, David T Harrington","doi":"10.1093/jbcr/iraf053","DOIUrl":"10.1093/jbcr/iraf053","url":null,"abstract":"<p><strong>Background: </strong>Burn registries play a crucial role in enhancing the understanding of burn epidemiology and improving clinical care. However, they often lack comprehensive data on post-discharge outcomes when patients transition to outpatient care. This study aimed to initiate the expansion of the American Burn Association's registry to include long-term outcomes for patients receiving outpatient follow-up post-discharge.</p><p><strong>Materials and methods: </strong>The Quality of Burn Registry Outpatient Work Group identified nine key long-term outcomes-five clinical and four psychosocial-to track after discharge from burn centers. An alpha pilot study was conducted with seven verified burn centers, collecting data on enrolled patients over 12 months in three-month intervals. A subsequent beta pilot involved ten centers, each monitoring five patients across five predefined cohorts.</p><p><strong>Results: </strong>The alpha pilot enrolled 29 patients, revealing variable documentation and data retrieval times of up to 15 minutes per patient. The beta pilot encompassed 200 patients and recorded 1417 appointments, averaging 7.1 visits per patient. Notably, 25% of patients were lost to follow-up, and 22% were discharged from care within 12 months. Follow-up visits were most concentrated in the first three months (53.6%).</p><p><strong>Discussion: </strong>This study represents a pioneering effort to systematically collect long-term outcomes for major burn injury survivors during the first year post-discharge. The findings will support ongoing improvements in best practices for burn care and enhance continuity between inpatient and outpatient monitoring, ultimately benefiting quality improvement initiatives for burn-injured patients in the future.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"886-893"},"PeriodicalIF":1.8,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143965706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the Scalpel Blade as an Objective Tool for Measuring Dermatome Cut Thickness.","authors":"Dallan P Dargan, Lawrence J Gottlieb, Sebastian Q Vrouwe","doi":"10.1093/jbcr/iraf067","DOIUrl":"10.1093/jbcr/iraf067","url":null,"abstract":"<p><p>Dermatomes are widely used for split-thickness skin graft harvest. The graft thickness depends in part on the cut thickness setting, adjusted by the surgeon using a lever on the dermatome. This study aimed to assess whether a #15 scalpel blade placed in the dermatome blade aperture may reliably confirm the cut thickness setting (the scalpel dermatome test). Discrepancies between the blade-measured aperture and the cut thickness setting and the intra- and inter-observer reliability of the technique were evaluated. The thickness of ten #15 blades (n = 10) was measured using a micrometer. Six dermatomes were each assessed by 2 surgeons in triplicate each for the narrowest cut thickness setting that would permit passage of an entire surgical blade through the dermatome blade aperture, starting at zero and increasing cut thickness intervals of 1/1000 in. The mean scalpel blade thickness was 0.391 mm (~15/1000 in.). The mean cut thickness setting that would permit the blade was 6/1000 in. (range 2-9), P < 0.001. Intra-observer reliability was good (intra-class correlation coefficient 0.89). Inter-observer reliability was moderate (intra-class correlation coefficient 0.52) and a mean difference of 1.5/1000 in. was observed (6.8 vs 5.2, t-test P < .018). Individual dermatome apertures differed, with the mean of 3 measurements for each ranging from 5.0 to 7.8/1000 in, P < .001. Differences exist between scalpel blades, dermatomes, and surgeons, however, intra-observer reliability is good. The test is a simple maneuver, which can objectively validate the dermatome blade aperture, thereby preventing harm and optimizing graft thickness.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"741-745"},"PeriodicalIF":1.8,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143998592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Post-Operative Mobilization After Treatment of Burn Wounds with Autologous Skin Cell Suspension is Safe.","authors":"Rohit Mittal, Jenna Kelly, Steven Alexander Kahn","doi":"10.1093/jbcr/iraf038","DOIUrl":"10.1093/jbcr/iraf038","url":null,"abstract":"<p><p>Standardized criteria for mobilization of the post-operative burn patient do not currently exist. Even the term \"early mobilization\" is not well defined. The use of autologous skin cell suspension (ASCS) with or without split-thickness skin grafts (STSG) has improved patient outcomes. The purpose of this study is to evaluate the safety of early post-operative mobilization, defined as mobilization with the rehabilitation team within 48 hour of surgical treatment, in patients who were treated with ASCS and a polylactic acid dressing. This is a single-center, retrospective review over a 10-month period of patients who presented with deep partial thickness and full-thickness burns. All burn wounds included in the study underwent surgical treatment of their burns with ASCS or ASCS+STSG. After surgical treatment, any patients/areas with post-operative restrictions were noted. All patients without restrictions were allowed active and/or passive range of motion (AROM or PROM) of the treated area and out-of-bed (OOB) mobilization starting on POD0. In total, 29 patients were treated with 77 separate areas undergoing surgical treatment with ASCS or ASCS + STSG; 79% of these areas involved joints. All patients underwent either AROM or PROM with the burn therapy team by POD2. Of the wounds treated with ASCS alone, 5% required patch grafting, and no graft loss was noted in those treated with STSG+ASCS. This study serves as a proof of concept that early post-operative mobilization in burn patients undergoing grafting and ASCS is safe and is not associated with graft loss, including areas involving joints.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"846-849"},"PeriodicalIF":1.8,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}