Melanie McCormick, Nicholas Larson, Rob Newsom, Sam A Miotke, Alexandra M Lacey
{"title":"Thrombolytic Therapy in Prepubescent Pediatric Frostbite Patients.","authors":"Melanie McCormick, Nicholas Larson, Rob Newsom, Sam A Miotke, Alexandra M Lacey","doi":"10.1093/jbcr/iraf116","DOIUrl":null,"url":null,"abstract":"<p><p>Frostbite injury in prepubescent children is rare and, as such, has limited research and guidelines specific to managing this population. Here, we present a five patient case series of all prepubescent pediatric patients with severe frostbite injury that were treated with thrombolytics at our ABA verified burn center. All patients were documented to have excellent preservation of tissue with no adverse effects related to thrombolytic administration. This case series underscores the potential of thrombolytic therapy in pediatric frostbite cases, paving the way for improved clinical outcomes and highlighting the necessity of further research to establish standardized treatment guidelines.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":""},"PeriodicalIF":1.5000,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Burn Care & Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/jbcr/iraf116","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CRITICAL CARE MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
Frostbite injury in prepubescent children is rare and, as such, has limited research and guidelines specific to managing this population. Here, we present a five patient case series of all prepubescent pediatric patients with severe frostbite injury that were treated with thrombolytics at our ABA verified burn center. All patients were documented to have excellent preservation of tissue with no adverse effects related to thrombolytic administration. This case series underscores the potential of thrombolytic therapy in pediatric frostbite cases, paving the way for improved clinical outcomes and highlighting the necessity of further research to establish standardized treatment guidelines.
期刊介绍:
Journal of Burn Care & Research provides the latest information on advances in burn prevention, research, education, delivery of acute care, and research to all members of the burn care team. As the official publication of the American Burn Association, this is the only U.S. journal devoted exclusively to the treatment and research of patients with burns. Original, peer-reviewed articles present the latest information on surgical procedures, acute care, reconstruction, burn prevention, and research and education. Other topics include physical therapy/occupational therapy, nutrition, current events in the evolving healthcare debate, and reports on the newest computer software for diagnostics and treatment. The Journal serves all burn care specialists, from physicians, nurses, and physical and occupational therapists to psychologists, counselors, and researchers.