Journal of Artificial Organs最新文献_第10页

Twisting of HeartMate II outflow graft 2.5 years after implantation-HM2 is still ongoing. 植入 2.5 年后，HeartMate II 流出移植物发生扭曲-HM2 仍在进行中。

IF 1.3 4区医学

Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2023-02-20 DOI: 10.1007/s10047-023-01387-y

Hiroaki Sakamoto, Hideyuki Kato, Toru Tsukada, Bryan J Mathis, Yuji Hiramatsu

引用次数: 0

A disposable edoxaban sensor chip using carbon paste electrode grafted with molecularly imprinted polymer. 使用分子印迹聚合物接枝碳糊电极的一次性埃多沙班传感器芯片。

IF 1.3 4区医学

Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2023-04-15 DOI: 10.1007/s10047-023-01392-1

Yasuo Yoshimi, Shohei Kani, Aaryashree

引用次数: 0

Building Effective Mentoring Relationships During Clinical Ethics Fellowships: Pedagogy, Programs, and People. 在临床伦理学研究期间建立有效的指导关系：教学法、计划和人员。

IF 1.5 4区医学

Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2022-02-26 DOI: 10.1007/s10730-022-09473-z

Trevor M Bibler, Ryan H Nelson, Bryanna Moore, Janet Malek, Mary A Majumder

引用次数: 0

Feasibility of concomitant exclusion of left atrial appendage during novel transapical off-pump beating heart mitral valve repair. 在新型经心尖离泵心脏跳动二尖瓣修复术中同时切除左房阑尾的可行性。

IF 1.3 4区医学

Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2023-02-08 DOI: 10.1007/s10047-023-01383-2

Daniel Tai-Leung Chan, Inderjeet Bhatia, Simon Chi-Cheung Lam, Timmy Wing-Kuk Au

{"title":"Feasibility of concomitant exclusion of left atrial appendage during novel transapical off-pump beating heart mitral valve repair.","authors":"Daniel Tai-Leung Chan, Inderjeet Bhatia, Simon Chi-Cheung Lam, Timmy Wing-Kuk Au","doi":"10.1007/s10047-023-01383-2","DOIUrl":"10.1007/s10047-023-01383-2","url":null,"abstract":"The AtriClip device enables the safe and reproducible epicardial clipping of the left atrial appendage. Transapical off-pump beating heart mitral valve repair using NeoChord DS100 Artificial Chordae Delivery System has matured and become more standardized. We aim to evaluate the feasibility of combining NeoChord repair and left atrial appendage exclusion in a single procedure through the same minithoracotomy in patients with mitral valve prolapse and atrial fibrillation. From 2018 to 2019, seven patients with severe mitral regurgitation and atrial fibrillation underwent transesophageal echocardiography-guided transapical off-pump mitral valve repair with the novel NeoChord DS 1000 system and concomitant left atrial appendage exclusion using the AtriClip Pro II device. Both procedures were performed via left mini-thoracotomy. The AtriClip device was applied after the NeoChord repair was done. All seven patients had less than moderate mitral regurgitation after the NeoChord repair and successful left atrial appendage occlusion. There were no device or procedure-related complications. Clinical follow-up revealed significant symptomatic improvement, and no cardiovascular complications were reported. Transesophageal echocardiography at 6-12 months post-procedure showed stable left atrial appendage occlusion with no residual flow between the left atrium and the left atrial appendage and a stump of less than 5 mm. Beating heart epicardial clipping of the left atrial appendage using AtriClip concomitant with transapical mitral valve repair using Neochord DS 1000 system is a feasible and safe treatment option in mitral valve prolapse and atrial fibrillation in patients with limited indications. However, its safety needs to be confirmed in a larger series of patients.","PeriodicalId":15177,"journal":{"name":"Journal of Artificial Organs","volume":" ","pages":"57-64"},"PeriodicalIF":1.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9907196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9237288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of adverse events related to extracorporeal membrane oxygenation from a nationwide database of patient-safety accidents in Japan. 日本全国患者安全事故数据库中与体外膜氧合相关的不良事件分析。

IF 1.3 4区医学

Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2023-02-16 DOI: 10.1007/s10047-023-01386-z

Hiroki Hadano, Tadashi Kamio, Kiyomitsu Fukaguchi, Mizuki Sato, Yumiko Tsunano, Hiroshi Koyama

{"title":"Analysis of adverse events related to extracorporeal membrane oxygenation from a nationwide database of patient-safety accidents in Japan.","authors":"Hiroki Hadano, Tadashi Kamio, Kiyomitsu Fukaguchi, Mizuki Sato, Yumiko Tsunano, Hiroshi Koyama","doi":"10.1007/s10047-023-01386-z","DOIUrl":"10.1007/s10047-023-01386-z","url":null,"abstract":"Although adverse events related to extracorporeal membrane oxygenation have been reported, epidemiological data on life-threatening events are insufficient to study the causes of such adverse events. Data from the Japan Council for Quality Health Care database were retrospectively analyzed. The adverse events extracted from this national database included events associated with extracorporeal membrane oxygenation reported between January 2010 and December 2021. We identified 178 adverse events related to extracorporeal membrane oxygenation. At least 41 (23%) and 47 (26%) accidents resulted in death and residual disability, respectively. The most common adverse events were cannula malposition (28%), decannulation (19%), and bleeding (15%). Among patients with cannula malposition, 38% did not undergo fluoroscopy-guided or ultrasound-guided cannulation, 54% required surgical treatment, and 18% required trans-arterial embolization. In this epidemiological study in Japan, 23% of the adverse events related to extracorporeal membrane oxygenation had fatal outcomes. Our findings suggest that a training system for cannulation techniques may be needed, and hospitals offering extracorporeal membrane oxygenation should perform emergency surgeries.","PeriodicalId":15177,"journal":{"name":"Journal of Artificial Organs","volume":" ","pages":"15-22"},"PeriodicalIF":1.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933024/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10738693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hemodynamic parameters at rest predicting exercise capacity in patients supported with left ventricular assist device. 预测使用左心室辅助装置的患者运动能力的静态血流动力学参数。

IF 1.3 4区医学

Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2023-03-18 DOI: 10.1007/s10047-023-01388-x

Hirotoshi Kato, Togo Iwahana, Ryohei Ono, Sho Okada, Goro Matsumiya, Yoshio Kobayashi

{"title":"Hemodynamic parameters at rest predicting exercise capacity in patients supported with left ventricular assist device.","authors":"Hirotoshi Kato, Togo Iwahana, Ryohei Ono, Sho Okada, Goro Matsumiya, Yoshio Kobayashi","doi":"10.1007/s10047-023-01388-x","DOIUrl":"10.1007/s10047-023-01388-x","url":null,"abstract":"Left ventricular assist devices improve prognosis and quality of life, but exercise capacity remains limited in most patients after device implantation. Left ventricular assist device optimization through right heart catheterization reduces device-related complications. However, hemodynamic parameters associated with exercise capacity under optimized conditions. The aim of this study was to elucidate the predictors of exercise capacity from hemodynamic parameters at rest after left ventricular assist device optimization. We retrospectively reviewed 24 patients who underwent a ramp test with right heart catheterization, echocardiography and cardiopulmonary exercise testing more than 6 months after left ventricular assist device implantation. Pump speed was optimized to a lower setting that achieved right atrial pressure < 12 mmHg, pulmonary capillary wedge pressure < 18 mmHg, and cardiac index > 2.2 L/min/m2, then exercise capacity was assessed by cardiopulmonary exercise testing. After left ventricular assist device optimization, the mean right atrial pressure, pulmonary capillary wedge pressure, cardiac index, and peak oxygen consumption were 7 ± 5 mmHg, 10 ± 7 mmHg, 2.7 ± 0.5 L/min/m2, and 13.2 ± 3.0 mL/min/kg, respectively. Pulse pressure, stroke volume, right atrial pressure, mean pulmonary artery pressure, and pulmonary capillary wedge pressure were significantly associated with peak oxygen consumption. Multivariate linear regression analysis of factors predicting peak oxygen consumption revealed that pulse pressure, right atrial pressure, and aortic insufficiency remained independent predictors (β = 0.401, p = 0.007; β = - 0.558, p < 0.001; β = - 0.369, p = 0.010, respectively). Our findings suggests that cardiac reserve, volume status, right ventricular function, and aortic insufficiency predict exercise capacity in patients with a left ventricular assist device.","PeriodicalId":15177,"journal":{"name":"Journal of Artificial Organs","volume":" ","pages":"7-14"},"PeriodicalIF":1.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9484748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evolutions of extracorporeal membrane oxygenator (ECMO): perspectives for advanced hollow fiber membrane. 体外膜氧合器（ECMO）的演变：先进中空纤维膜的前景。

IF 1.3 4区医学

Journal of Artificial Organs Pub Date : 2024-03-01 Epub Date: 2023-03-14 DOI: 10.1007/s10047-023-01389-w

Makoto Fukuda

{"title":"Evolutions of extracorporeal membrane oxygenator (ECMO): perspectives for advanced hollow fiber membrane.","authors":"Makoto Fukuda","doi":"10.1007/s10047-023-01389-w","DOIUrl":"10.1007/s10047-023-01389-w","url":null,"abstract":"Hollow fiber membrane is incorporated into an extracorporeal membrane oxygenator (ECMO), and the function of the membrane determines the ECMO's functions, such as gas transfer rate, biocompatibility, and durability. In Japan, the membrane oxygenator to assist circulation and ventilation is approved for ECMO support. However, in all cases, the maximum use period has been only 6 h, and so-called 'off-label use' is common for ECMO support of severely ill COVID-19 patients. Under these circumstances, the HLS SET Advanced (Getinge Group Japan K.K.) was approved in 2020 for the first time in Japan as a membrane oxygenator with a two-week period of use. Following this membrane oxygenator, it is necessary to establish a domestic ECMO system that is approved for long-term use and suitable for supporting patients. Looking back on the evolution of ECMO so far, Japanese researchers and manufacturers have also contributed to the developments of ECMO globally. Currently, excellent membrane oxygenators and systems have been marketed by Japanese manufacturers and some of them are globally acclaimed, but in fact, most of the ECMO membranes are not made in Japan. Fortunately, Japan has led the world in the fields of membrane separation technology and hollow fiber membrane production. In the wake of this pandemic, from the perspective of medical and economic security, the practical use of purely domestic hollow fiber membranes and membrane oxygenators for long-term ECMO is imperative in anticipation of the next pandemic.","PeriodicalId":15177,"journal":{"name":"Journal of Artificial Organs","volume":" ","pages":"1-6"},"PeriodicalIF":1.3,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010948/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9120994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Contributing factors to heparin resistance during cardiopulmonary bypass 心肺旁路过程中肝素抵抗的诱因

IF 1.3 4区医学

Journal of Artificial Organs Pub Date : 2024-02-17 DOI: 10.1007/s10047-024-01435-1

{"title":"Contributing factors to heparin resistance during cardiopulmonary bypass","authors":"","doi":"10.1007/s10047-024-01435-1","DOIUrl":"https://doi.org/10.1007/s10047-024-01435-1","url":null,"abstract":"<h3>Abstract</h3> Since the risk factors for heparin resistance (HR) before cardiopulmonary bypass (CPB) have not been fully clarified, this study investigated the contributing factors for HR after the initial unfractionated heparin (UFH) dose of 500 IU/kg. We retrospectively analyzed the data of 371 patients who underwent CPB surgery, with the initial UFH dose of 500 IU/kg, between May 2017 and December 2021. We defined HR as the failure to achieve activated clotting time (ACT) of > 480 s after the initial UFH dose of 500 IU/kg. HR was observed in 36 patients (9.7%) (HR group), while HR was not observed in 335 patients (control group). The HR group included significantly more patients with preoperative use of UFH, with significantly higher white blood cell counts, fibrinogen, fibrinogen degradation products, d-dimer, and C-reactive protein, and lower hemoglobin and albumin. The multivariable logistic regression analysis identified albumin (OR: 3.09, 95% CI 1.3504–7.0845, p = 0.0075) and fibrinogen (OR: 0.99, 95% CI 0.9869–0.9963, p = 0.0003) as independent predictors for HR. Using the Youden index, the cutoffs of albumin and fibrinogen were calculated as 3.8 g/dL and 303 mg/dL, respectively. The receiver operating characteristic curves showed the predictive performance of albumin (area under the curve (AUC): 0.78, sensitivity: 65%, specificity: 81%) and fibrinogen (AUC: 0.77, sensitivity: 56%, specificity: 88%). The incidence of HR after the initial UFH dose of 500 IU/kg was 9.7%. The preoperative albumin < 3.8 g/dL and fibrinogen > 303 mg/dL were independent predictors for HR.","PeriodicalId":15177,"journal":{"name":"Journal of Artificial Organs","volume":"16 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139755442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanical support for bridge to transplant in an infant with post-cardiotomy end-stage heart failure and complete heart block: report of a case 机械支持为心脏切除术后终末期心力衰竭和完全性心脏传导阻滞的婴儿搭建移植桥梁：病例报告

IF 1.3 4区医学

Journal of Artificial Organs Pub Date : 2023-12-29 DOI: 10.1007/s10047-023-01425-9

Haruhiro Nagase, Takaya Hoashi, Koichi Toda, Kentaro Hotoda, Yuji Fuchigami, Yukino Iijima, Takaaki Suzuki

{"title":"Mechanical support for bridge to transplant in an infant with post-cardiotomy end-stage heart failure and complete heart block: report of a case","authors":"Haruhiro Nagase, Takaya Hoashi, Koichi Toda, Kentaro Hotoda, Yuji Fuchigami, Yukino Iijima, Takaaki Suzuki","doi":"10.1007/s10047-023-01425-9","DOIUrl":"https://doi.org/10.1007/s10047-023-01425-9","url":null,"abstract":"The patient was diagnosed with perimembranous ventricular septal defect (VSD). She underwent VSD closure and muscle bundle resection across right ventricular outflow tract at the age of 3 months. Since then, she had suffered from severe heart failure and complete heart block. Permanent pacemaker generator was implanted in the left hypochondrium. She was depended on continuous catecholamine administration, so transferred to our hospital for further management. On arrival, her body weight was 5686 g (− 2.7 SD). She underwent Excor pediatric left ventricular assist device implantation at the age of 9 months. Because the position of the left ventricular assist device cannula interfered with the pacemaker, herein, the pacemaker pocket was newly created in the left thoracic cavity. An 1 mm in thickness of expanded polytetrafluoroethylene sheet was trimmed and sutured under the anterolateral wall of left thoracic cavity as a pacemaker pocket. Bipolar ventricular lead was sutured on left ventricular apex and basal wall to face each other, mimicking cardiac regeneration therapy. Even though she unfortunately required right diaphragmatic plication for iatrogenic phrenic nerve palsy, her respiratory function was well maintained; therefore, secondary right heart failure was not observed. Her cardiopulmonary function was quite stable until post-operative day 275 when the patient was transferred to another hospital for heart transplantation.","PeriodicalId":15177,"journal":{"name":"Journal of Artificial Organs","volume":"138 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139070561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EVAHEART 2 with double cuff tipless inflow cannula is suitable for long-term support atrial switch operation in transposition of great arteries. EVAHEART 2双袖带无尖端流入套管适用于大动脉转位的长期支持心房开关手术。

IF 1.3 4区医学

Journal of Artificial Organs Pub Date : 2023-12-01 Epub Date: 2023-01-23 DOI: 10.1007/s10047-023-01380-5

Sawako Furukawa, Osamu Kinoshita, Masahiko Ando, Minoru Ono

引用次数: 0