Journal of biomechanics最新文献

Acute effects of isometric plantarflexion exercise on Achilles tendon non-uniform displacement

IF 2.4 3区医学

Journal of biomechanics Pub Date : 2025-03-01 DOI: 10.1016/j.jbiomech.2025.112614

Roosa Parkkola , Maria Sukanen , Ra’ad M. Khair , Karin Grävare Silbernagel , Taija Finni

{"title":"Acute effects of isometric plantarflexion exercise on Achilles tendon non-uniform displacement","authors":"Roosa Parkkola , Maria Sukanen , Ra’ad M. Khair , Karin Grävare Silbernagel , Taija Finni","doi":"10.1016/j.jbiomech.2025.112614","DOIUrl":"10.1016/j.jbiomech.2025.112614","url":null,"abstract":"<div><div>Non-uniform displacement is a well-documented phenomenon of healthy tendons that has shown to be reduced among injured and aging populations. Non-uniformity is considered a biomarker of tendon health, yet immediate response to physical exercise is unknown. This study examined acute changes in Achilles tendon (AT) non-uniform displacement in response to high strain magnitude isometric plantarflexion exercise. The reliability of the method was also examined. Fourteen healthy participants (7 men, 7 women, mean ± SD age: 26.4 ± 4.8 years) performed unilateral isometric plantarflexion exercise at 90 % of maximal voluntary isometric contractions (MVIC) with 5 sets of 4 repetitions, each lasting 3 s. The contralateral leg served as control. AT displacement was measured during ramp contractions to a constant torque level (30 % of MVIC) before the exercise, between the loading sets, and six times during 72-h recovery period. AT nonuniformity (difference between maximum and minimum displacement) was analyzed from sagittal B-mode ultrasound videos using speckle tracking. Two-way repeated measures ANOVA was used to compare the values across different timepoints. Non-uniformity did not change in response to exercise and was 2.99 ± 1.52 mm before and 3.19 ± 1.42 mm immediately after exercise. The reliability of non-uniformity between trials within a single measurement session varied from moderate to excellent (ICC: 0.680–0.920). While the isometric high strain plantarflexion exercise did not acutely alter the non-uniform displacement of the AT in young healthy adults, strenuous exercises containing knee and ankle joint angle changes should be investigated to confirm adaptability of AT non-uniform displacement.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"183 ","pages":"Article 112614"},"PeriodicalIF":2.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143534745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validation of OpenCap on lower extremity kinematics during functional tasks

IF 2.4 3区医学

Journal of biomechanics Pub Date : 2025-02-28 DOI: 10.1016/j.jbiomech.2025.112602

Ainsley Svetek , Kristin Morgan , Julie Burland , Neal R. Glaviano

{"title":"Validation of OpenCap on lower extremity kinematics during functional tasks","authors":"Ainsley Svetek , Kristin Morgan , Julie Burland , Neal R. Glaviano","doi":"10.1016/j.jbiomech.2025.112602","DOIUrl":"10.1016/j.jbiomech.2025.112602","url":null,"abstract":"<div><div>Marker-based motion capture is a fundamental tool in biomechanical analysis, yet comes with major constraints such as time, cost and accessibility. This study aimed to validate the use of OpenCap, a free, markerless motion capture system compared to a marker-based motion capture system to measure lower extremity kinematics during functional tasks. 20 individuals from an athletic population (18 females, 2 males) performed two gait trials (walking, running) and three functional tasks (double leg squat, countermovement jump, jump-landing). Lower extremity peak joint kinematics were collected simultaneously using Vicon and OpenCap to assess the validity of markerless motion capture. Strong agreements were observed in the frontal hip plane joint kinematics across all tasks with root mean squared errors below 6°. Moderate agreements were observed in the sagittal knee plane joint kinematics (4–10°) and there was a weak agreement in the gait trials of the sagittal hip measures (>10°). The results from the study indicate the need for further research on the use of OpenCap in clinical settings. The findings align with previous studies with similar agreements observed in the frontal hip and sagittal knee measures. Validating the use of an open-source motion capture software could provide clinicians and researchers an accessible tool for in depth biomechanical assessments.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"183 ","pages":"Article 112602"},"PeriodicalIF":2.4,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143552160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Load transfer between active and passive lumbar tissues and its implications in time-dependent EMG-assisted biomechanical modeling

IF 2.4 3区医学

Journal of biomechanics Pub Date : 2025-02-27 DOI: 10.1016/j.jbiomech.2025.112600

Sang Hyeon Kang , Gary A. Mirka

{"title":"Load transfer between active and passive lumbar tissues and its implications in time-dependent EMG-assisted biomechanical modeling","authors":"Sang Hyeon Kang , Gary A. Mirka","doi":"10.1016/j.jbiomech.2025.112600","DOIUrl":"10.1016/j.jbiomech.2025.112600","url":null,"abstract":"<div><div>Electromyography (EMG)-assisted biomechanical models of the lumbar spine have been developed to estimate spinal loading, but these models often have limited representation of passive tissue contributions to the trunk extension moment. Recent evidence suggests that sustained near full trunk flexion can lead to increased contribution of the passive tissues to resist the external moment due to increased lumbar flexion as the extensor muscle fatigue. This leads to our hypothesis that spinal loading might be increased due to load transfers between active and passive tissues. Sixteen participants maintained a trunk flexion posture that was ten degrees less than the trunk flexion angle inducing flexion-relaxation of erector spinae muscles for 12 min with breaks every three minutes. Trunk kinematic and EMG measures were collected. A muscle fatigue-modified EMG-assisted model with passive tissue components was employed to estimate the time-dependent force and moment profiles at the L4/L5 level. Results revealed that these postures led to a time-dependent increase in the proportion of passive tissues to resist the external moment (39.9 % to 49.5 %) during each 3-minute time block, thereby resulting in the time-dependent increase in the compression and anterior-posterior shear forces of the L4/L5 disc by 181.7 N and 125.2 N, respectively (all p-value < 0.001). These results indicate that the load transfer from active to passive tissues can lead to increased compression and anterior-posterior shear forces of the L4/L5 disc at a constant external moment. This study suggests that a time-dependent approach to an EMG-assisted model with passive tissue components can provide more accurate estimates of tissue stresses.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"183 ","pages":"Article 112600"},"PeriodicalIF":2.4,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143529201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Proactive modifications to walking stability under the threat of large, anterior or posterior perturbations

IF 2.4 3区医学

Journal of biomechanics Pub Date : 2025-02-26 DOI: 10.1016/j.jbiomech.2025.112599

James B. Tracy , Jocelyn F. Hafer , J. Hendrik Reimann , Thomas A. Buckley , Jessica L. Allen , Jeremy R. Crenshaw

{"title":"Proactive modifications to walking stability under the threat of large, anterior or posterior perturbations","authors":"James B. Tracy , Jocelyn F. Hafer , J. Hendrik Reimann , Thomas A. Buckley , Jessica L. Allen , Jeremy R. Crenshaw","doi":"10.1016/j.jbiomech.2025.112599","DOIUrl":"10.1016/j.jbiomech.2025.112599","url":null,"abstract":"<div><div>Biomechanically, falling after a walking perturbation may be influenced by: (1) the pre-perturbation state of mechanical stability (e.g., stability margins) and (2) the response to a perturbation (i.e., recovery skill). Walking stability margins must be modifiable to serve as a target for fall-prevention interventions. We investigated if neurotypical adults could proactively modulate pre-perturbation anteroposterior stability margins while walking. Eleven adults walked on a treadmill at three speeds with and without anterior and posterior perturbations. We measured stability margins anteriorly at mid-swing and posteriorly at foot strike for pre-perturbation steps. A repeated-measures factorial ANOVA evaluated main effects and interactions of walking speed (0.6, 0.8, 1.0 stats/s) and perturbation type (anterior, none, posterior). With posterior perturbation threats, the posterior stability margins were more positive at foot strike (p < 0.01) compared to trials without perturbations. With anterior perturbation threats, the anterior stability margins were not different at mid-swing compared to trials without perturbations (p > 0.05). With any perturbation threat, step lengths shortened (p < 0.01) and step rates increased (p < 0.01). Step width was not different (p > 0.11). At slow speeds with posterior perturbation threats, double-support time decreased (p = 0.04). Proactive modifications to stability margins are indeed possible in a neurotypical population. Consequently, anteroposterior stability margins may be a feasible target for fall-prevention interventions by targeting decreased step lengths or increased step rates within a given walking speed. We do not know the extent to which the observed effects have a meaningful effect on perturbation recovery.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"183 ","pages":"Article 112599"},"PeriodicalIF":2.4,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143526664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Morphological analysis of the median nerve in the carpal tunnel during wrist movements, finger pinching and palm loading 手腕运动、手指捏紧和手掌加载时腕管内正中神经的形态分析

IF 2.4 3区医学

Journal of biomechanics Pub Date : 2025-02-26 DOI: 10.1016/j.jbiomech.2025.112601

Long Yin , Yuan Guo , Xushu Zhang , Haibo Ke , Fengyi Zhou , Yiting Du , Kai Zhang , Binping Ji , Yunpeng Wen

{"title":"Morphological analysis of the median nerve in the carpal tunnel during wrist movements, finger pinching and palm loading","authors":"Long Yin , Yuan Guo , Xushu Zhang , Haibo Ke , Fengyi Zhou , Yiting Du , Kai Zhang , Binping Ji , Yunpeng Wen","doi":"10.1016/j.jbiomech.2025.112601","DOIUrl":"10.1016/j.jbiomech.2025.112601","url":null,"abstract":"<div><div>The aim of this study was to analyze the morphology of the median nerve (MN) in the carpal tunnel during hand motion and palmar load in healthy participants using ultrasound. Twenty healthy participants (10 men and 10 women) were enrolled in the study. Wrist flexion angle is negatively correlated with cross-sectional area (CSA) and perimeter, and positively correlated with circularity, whereas wrist extension angle is negatively correlated with MNCSA and circularity. At 15°, 45°, and 60° wrist flexion and extension, both MNCSA and perimeter were significantly smaller than at neutral (all <em>P</em> < 0.05). MN circularity was significantly greater at 30°, 45°, and 60° wrist flexion than at neutral (all <em>P</em> < 0.05). At 30° ulnar deviation of the wrist, MNCSA and perimeter were significantly smaller than the neutral position, while circularity was significantly larger (all <em>P</em> < 0.05). At 15° of wrist radial deviation, MNCSA and perimeter were significantly smaller than at the neutral position (all <em>P</em> < 0.05). Compared to the 40 % maximum voluntary effort (MVE), thumb-ring finger pinch (10 %MVE) resulted in significantly higher MNCSA and perimeter, while circularity was noticeably smaller (all <em>P</em> < 0.05). In the neutral position, no differences were observed in MNCSA, perimeter and circularity unloaded at 100 g, 200 g, 300 g, 400 g and 500 g palmar loads (all <em>P</em> > 0.05). The results indicate that wrist positions involving flexion, extension, and deviations, as well as finger pinch, can significantly impact the morphology of the MN. This is an important step in understanding the biomechanics of MN compression within the carpal tunnel.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"183 ","pages":"Article 112601"},"PeriodicalIF":2.4,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143526663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dynamic compression modulates anabolic and catabolic activity in chondrocyte seeded agarose constructs

IF 2.4 3区医学

Journal of biomechanics Pub Date : 2025-02-22 DOI: 10.1016/j.jbiomech.2025.112598

Lea Zila , Roberto Tarantino , Peter Zastawny , Stephen D Waldman

{"title":"Dynamic compression modulates anabolic and catabolic activity in chondrocyte seeded agarose constructs","authors":"Lea Zila , Roberto Tarantino , Peter Zastawny , Stephen D Waldman","doi":"10.1016/j.jbiomech.2025.112598","DOIUrl":"10.1016/j.jbiomech.2025.112598","url":null,"abstract":"<div><div>Mechanical stimulation is a widely used technique in the development of tissue engineered cartilage. While various regimes can enhance tissue growth and improve construct mechanical properties, existing outcome measures predominantly assess the anabolic effect of mechanical stimuli. Catabolic responses are generally overlooked, and a critical gap remains in how mechanical loading simultaneously affects both anabolic and catabolic processes. In this study, full-thickness articular cartilage was aseptically harvested from the metacarpal-phalangeal joints of skeletally mature bovine. Isolated chondrocytes were encapsulated in agarose gels and subjected to dynamic compressive strains from 0 % to 15 % for either 20 or 60 min using a custom-built mechanical stimulation device. Anabolism was assessed by [<sup>3</sup>H]-proline and [<sup>35</sup>S]-sulfate incorporation, while catabolism was evaluated by MMP-13 enzymatic activity. Long-term effects of dynamic loading were assessed through biochemical analyses and histological evaluation. Results showed that low-to-moderate strains (2.5 % and 5 %) induced high anabolic activity relative to control with minimal catabolic response. In contrast, high strains (15 %) resulted in elevated catabolic and reduced anabolic activity relative to control. The application of mechanical stimuli over the long-term elicited comparable responses with lower compressive stains leading to improved cartilaginous extracellular matrix accumulation. This study provides valuable insights into the complex interplay between anabolic and catabolic metabolism in chondrocyte-seeded agarose constructs subjected to dynamic compression. This research underscores the necessity of evaluating both responses to optimize the growth and properties of tissue-engineered cartilage.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"183 ","pages":"Article 112598"},"PeriodicalIF":2.4,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Connecting developed pressure – Preload relationship in ex-vivo beating heart with cellular sarcomere length – Tension relationship

IF 2.4 3区医学

Journal of biomechanics Pub Date : 2025-02-22 DOI: 10.1016/j.jbiomech.2025.112597

Lei Fan , Vahid Ziaei-Rad , Jason Bazil , Lik Chuan Lee

{"title":"Connecting developed pressure – Preload relationship in ex-vivo beating heart with cellular sarcomere length – Tension relationship","authors":"Lei Fan , Vahid Ziaei-Rad , Jason Bazil , Lik Chuan Lee","doi":"10.1016/j.jbiomech.2025.112597","DOIUrl":"10.1016/j.jbiomech.2025.112597","url":null,"abstract":"<div><div>The heart’s developed pressure (DP) in Langendorff heart experiments increases with preload via the Frank-Starling mechanism up to a critical transition point at which DP starts to decrease with preload. A similar behavior is found at the cellular level, where the tension developed by skinned cardiac fibers or myocytes in isometric tension test increases with sarcomere length up to a transition point beyond which, the tension decreases. This cellular-level behavior is termed myofilament length dependent activation. While these two behaviors are similar, they occur at vastly different scales. Specifically, the DP – preload and sarcomere length – tension relationships occur, respectively, at the organ and cellular scales. Correspondingly, it remains unclear how much these behaviors are related. To address this issue, we use computer modeling that connects cellular to organ mechanics found in the <em>ex-vivo</em> beating rat heart experiments to determine whether the DP – preload relationship at the organ level can be explained solely by the sarcomere length – tension relationship at the cellular level. We found that the non-monotonic behavior of the DP with preload is consistent with a model predicted feature of myocardial contractility. The LV sarcomere length at the transition where DP and myocardial contractility start to reduce is 2.12 ± 0.03 <span><math><mrow><mi>μ</mi><mi>m</mi></mrow></math></span>. This transition sarcomere length is outside the range of 2.2 – 2.4 <span><math><mrow><mi>μ</mi><mi>m</mi></mrow></math></span> that is associated with the peak tension found in skinned rat cardiac fibers or myocytes with isometric tension test. This disparity suggests the presence of other factors affecting the DP – preload relationship found in Langendorff heart experiments such as the prescribed initial length of sarcomere that vary between different rat species.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"183 ","pages":"Article 112597"},"PeriodicalIF":2.4,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143487229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Facet joint distance measurement using digital tomosynthesis while standing

IF 2.4 3区医学

Journal of biomechanics Pub Date : 2025-02-21 DOI: 10.1016/j.jbiomech.2025.112596

Daniel Oravec , Razeen Zaman , Sudhaker Rao , Victor Chang , George Divine , Yener N. Yeni

{"title":"Facet joint distance measurement using digital tomosynthesis while standing","authors":"Daniel Oravec , Razeen Zaman , Sudhaker Rao , Victor Chang , George Divine , Yener N. Yeni","doi":"10.1016/j.jbiomech.2025.112596","DOIUrl":"10.1016/j.jbiomech.2025.112596","url":null,"abstract":"<div><div>The zygapophyseal (facet) joint plays a critical role in load transmission and stability of the spine, and facet degeneration is a common consequence of aging and osteoarthritis. The ability to accurately measure facet space is important, as decreased facet space is associated with facet degeneration and lower back pain. Although grading systems exist for assessing facet joint space narrowing, static imaging fails to characterize changes in the facet gap under load that play a role in segmental stability. Current methods for estimating the dynamic behavior of the facet joint are either inaccurate, radiation costly, or clinically impractical. In the current study, we demonstrate the feasibility of a novel method for 3D measurement of facet joint space using digital tomosynthesis (DTS) imaging in supine and standing positions. Facet gap measurements were found to be strongly correlated with (r to 0.98) and accurate (<20 µm error for median facet gap) relative to microcomputed tomography reference values. In a pilot <em>in vivo</em> demonstration with seven participants, the effect of physiological loading was detectable, with median facet joint space being larger in standing as compared to supine images (p < 0.0001). The presented approach may be useful in directly characterizing changes in the facet joint relevant to segmental stability that are not readily assessed via current clinical imaging methods.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"183 ","pages":"Article 112596"},"PeriodicalIF":2.4,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Creep deformation of viscoelastic lumbar tissue and its implication in biomechanical modeling of the lumbar spine

IF 2.4 3区医学

Journal of biomechanics Pub Date : 2025-02-20 DOI: 10.1016/j.jbiomech.2025.112595

Sang Hyeon Kang , Gary A. Mirka

{"title":"Creep deformation of viscoelastic lumbar tissue and its implication in biomechanical modeling of the lumbar spine","authors":"Sang Hyeon Kang , Gary A. Mirka","doi":"10.1016/j.jbiomech.2025.112595","DOIUrl":"10.1016/j.jbiomech.2025.112595","url":null,"abstract":"<div><div>Creep in the viscoelastic tissues of the lumbar spine reduces the force-producing capability of these tissues. This study aimed to explore the impact of passive tissue creep on lumbar biomechanics. Sixteen participants performed controlled sagittally symmetric trunk flexion motions after a 30-minute protocol consisting of 12 min of full trunk flexion and 18 min of upright standing. Trunk kinematics and EMG activities of trunk muscles were captured as input variables in three biomechanical models: a) EMG-assisted model with no passive tissue (Active), b) EMG-assisted model with time-invariant passive tissue (No-Creep), and c) EMG-assisted model with time-variant passive tissue components (Creep). The mean absolute error (MAE) between the external moment and the estimated internal moment was calculated as a function of model type and trunk flexion. Results revealed no significant difference in MAE between the three models at 0-30° trunk flexion but as the angle exceeded 30°, the MAE of the No-Creep and Creep models were significantly smaller than that of the Active model. Beyond thetrunk flexion angle of flexion-relaxation of erector spinae muscles, the MAE of the Creep model was significantly smaller than that of the No-Creep model (21.8 Nm vs. 40.3 Nm), leading to reduced compression and shear forces of the L4/L5 disc by 784.7 N (31.7 %) and 280.6 N (21.6 %) at full flexion. These results indicate the modulation of the time-dependent stiffness of passive tissues led to amore accurate prediction of the net internal moment at near full flexion postures, preventing overestimation of spinal loads.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"182 ","pages":"Article 112595"},"PeriodicalIF":2.4,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143474294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The influence of different stress loading on the biomechanics of motion segments in isolated rabbit spines 不同应力载荷对离体兔脊柱运动节段生物力学的影响

IF 2.4 3区医学

Journal of biomechanics Pub Date : 2025-02-19 DOI: 10.1016/j.jbiomech.2025.112592

Tao Han , Pengren Luo , Chuhao Cai , Xunlu Yin , Ming Chen , Xin Chen , Wei Peng , Jiawen Zhan , Zhefeng Jin , Liguo Zhu

{"title":"The influence of different stress loading on the biomechanics of motion segments in isolated rabbit spines","authors":"Tao Han , Pengren Luo , Chuhao Cai , Xunlu Yin , Ming Chen , Xin Chen , Wei Peng , Jiawen Zhan , Zhefeng Jin , Liguo Zhu","doi":"10.1016/j.jbiomech.2025.112592","DOIUrl":"10.1016/j.jbiomech.2025.112592","url":null,"abstract":"<div><div>Intervertebral disc degeneration greatly affects daily life. Suitable mechanical stress is important for intervertebral disc health as it affects disc cells. Research shows it helps disc cell proliferation and collagen synthesis. However, the influences of forces in diverse directions on the intervertebral disc remain ambiguous.</div><div>Our study aimed to investigate the impact of stress in various directions on intervertebral discs in New Zealand rabbits. The rabbit model was used because our team previously had established and validated it,which providing an effective platform for researching disc degeneration and treatment methods.</div><div>We resected the spinal L3/4 and L5/6 motion segments and categorized them into 5 groups. Apart from the control group, distinct mechanical loads (pressure, traction, rotation, rotational traction) were applied to the remaining groups. After mechanical intervention, in contrast to the other groups except for the control group, it was found that the creep displacement in the rotational traction force group was the lowest (0.90 ± 0.06), the fatigue resistance was enhanced, and the tensile strength was increased, showing advantages over the other groups (p < 0.05). Histological examination revealed that the rotational traction force group had a protective effect on the intervertebral disc structure, while the cell damage in the rotational force group was the most severe. This study will help understand the unique effects of stresses in different directions on the intervertebral disc. The general public should avoid direct rotational movements in daily life. Physicians can explore the therapeutic effect of rotational movements under traction on lumbar degenerative changes.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"182 ","pages":"Article 112592"},"PeriodicalIF":2.4,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143471443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0