Journal of biomechanics最新文献

{"title":"Structural optimization of biodegradable tracheal stent based on mechanical properties of trachea","authors":"Yuanming Gao ,&nbsp;Peng Ye ,&nbsp;Buyu Deng ,&nbsp;Mingkai Liang ,&nbsp;Zhengjie Liang ,&nbsp;Wentao Feng ,&nbsp;Lizhen Wang ,&nbsp;Yubo Fan","doi":"10.1016/j.jbiomech.2025.112757","DOIUrl":"10.1016/j.jbiomech.2025.112757","url":null,"abstract":"<div><div>Tracheal stent implantation serves as a critical intervention for tracheal stenosis, where biodegradable magnesium (Mg) alloy stents have emerged as promising alternatives due to their ability to eliminate long-term complications associated with permanent stents. However, the uneven stress distribution on the stent often leads to premature failure through localized rapid degradation and structural collapse. This study systematically investigated the biomechanical interactions between biodegradable stents and tracheal tissues to guide optimized stent design. The mechanical properties of tracheal cartilage under physiological curvature conditions were quantitatively characterized using custom-designed tissue fixtures. Finite element analysis was employed to simulate Mg alloy stent interaction with the trachea during both normal breathing and coughing, which revealed that the stent’s regions adjacent to the cartilage and membranous wall junction are high-risk regions for fractures. To address these challenges, the non-uniform stent design was proposed to enhance radial support and distribute stresses more evenly, thereby improving the resistance to localized degradation and premature fracture. The findings provide biomechanical insights and technical strategies for the development of biodegradable tracheal stents.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"188 ","pages":"Article 112757"},"PeriodicalIF":2.4,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144134679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to \"Step velocity asymmetry rather than step length asymmetry is updated in split-belt treadmill adaptation\" [J. Biomechan. 182 (2025) 112564].","authors":"Yuki Ishida, Hikaru Yokoyama, Naotsugu Kaneko, Tatsuya Kato, Kei-Ichi Ishikawa, Kimitaka Nakazawa, Ken Takiyama","doi":"10.1016/j.jbiomech.2025.112736","DOIUrl":"https://doi.org/10.1016/j.jbiomech.2025.112736","url":null,"abstract":"","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":" ","pages":"112736"},"PeriodicalIF":2.4,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144078271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inefficient impact absorption and reduced shock attenuation in female runners with stress urinary incontinence","authors":"Natália Cardoso Campos,&nbsp;Sérgio Teixeira Fonseca,&nbsp;Laura Jardim Nunes,&nbsp;Samá Isabela Ramos Rodrigues,&nbsp;Elyonara Mello Figueiredo,&nbsp;Priscila Albuquerque de Araújo,&nbsp;Mariana Rodrigues Carvalho de Aquino,&nbsp;Líria Okai-Nóbrega,&nbsp;Juliana Melo Ocarino,&nbsp;Thales Rezende Souza,&nbsp;Mariana Maia de Oliveira Sunemi,&nbsp;Renan Alves Resende","doi":"10.1016/j.jbiomech.2025.112753","DOIUrl":"10.1016/j.jbiomech.2025.112753","url":null,"abstract":"<div><div>Running has been associated with stress urinary incontinence (SUI) in female runners, with prevalence reaching 44 %. Surprisingly, many of these runners exhibit pelvic floor muscle strength and endurance that is similar or even greater compared to continent runners. Therefore, this study aimed to investigate other potential mechanisms associated with SUI in female runners, focusing on impact absorption and muscle function. Thirty-two female runners were divided into two groups: runners with and without SUI. Pelvic floor muscle function was assessed using the Peritron®, whereas the maximum isometric strength of the trunk and lower limb muscles was measured using a portable handheld dynamometer. Kinetic data, including vertical ground reaction force (GRF), energy absorption at the ankle, knee, and hip joints, and shock attenuation between the tibia and femur, were collected using a 3-D motion analysis system on an instrumented treadmill during running. Group comparisons were performed using the Student <em>t</em>-test and Mann-Whitney at a 0.05 significance level. There were no differences in pelvic floor, trunk and lower limb muscle function between groups. Despite similar vertical GRF, runners with SUI exhibited lower energy absorption at the ankle (p = 0.019; d = 0.54), higher energy absorption at the hip (p &lt; 0.001; d = 0.85) and reduced shock attenuation between the tibia and femur (p = 0.038; d = 0.80) during running compared to continent runners. Runners with SUI differed in energy absorption and shock attenuation patterns, particularly at the hip and ankle. These findings suggest that incontinent runners exhibit inefficient energy absorption throughout the kinetic chain experiencing greater pelvic demands.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"187 ","pages":"Article 112753"},"PeriodicalIF":2.4,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144099310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel method for Mytilus galloprovincialis adductor muscle activity measurement during and after physical stimulation","authors":"Akihiro Hamaya,&nbsp;Kazuhiro Fujisaki,&nbsp;Kazuhiko Sasagawa,&nbsp;Kotaro Miura","doi":"10.1016/j.jbiomech.2025.112754","DOIUrl":"10.1016/j.jbiomech.2025.112754","url":null,"abstract":"<div><div>Bivalves protect themselves from other marine organisms and environmental change by closing their valves. Although prior studies have investigated the mechanical aspects of bivalves, such as their fatigue resistance, none have measured the adductor muscle force in live bivalves in seawater due to the difficulty in directly measuring the adductor muscle force. In this study, the deformation of the valve surface caused by valve closing was investigated by focusing on the evaluation of muscle activity in bivalves. Changes in valve strain when <em>Mytilus galloprovincialis</em> samples with different shell lengths were stimulated in artificial seawater were measured using strain gauges. The adductor muscle forces estimated from the valve strain using loading tests for force calibration were used to quantitatively evaluate the magnitude of the maximum adductor muscle forces and duration characteristics. Contraction duration was not significantly correlated with either shell length or muscle cross-sectional area (shell length; <em>r</em> = 0.423, <em>p</em> = 0.404, muscle cross-sectional area; <em>r</em> = 0.140, <em>p</em> = 0.791). On the other hand, there was a highly significant correlation between adductor muscle force and cross-sectional area (<em>r</em> = 0.890, <em>p</em> = 0.017). The stress estimated in this study was 0.253 ± 0.026 MPa, which was smaller than the result of loading tests for shell opening in <em>Mytilus galloprovincialis</em> living samples obtained in previous studies. These results confirmed that this method can effectively evaluated muscle force changes, such as duration characteristics, during valve closing.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"187 ","pages":"Article 112754"},"PeriodicalIF":2.4,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144072530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of articulated ankle–foot orthosis dorsiflexion range of motion on lower-limb joint kinematics during gait in individuals post-stroke","authors":"Yufan He ,&nbsp;Mark W.P. Koh ,&nbsp;Chloe L.Y. Wong ,&nbsp;Fan Gao ,&nbsp;Toshiki Kobayashi","doi":"10.1016/j.jbiomech.2025.112755","DOIUrl":"10.1016/j.jbiomech.2025.112755","url":null,"abstract":"<div><div>Adjusting the range of motion (ROM) and spring stiffness of ankle–foot orthoses (AFOs) for individuals post-stroke enables customized functionality and targeted support during specific phases of the gait cycle. Modifications to dorsiflexion ROM or spring stiffness theoretically influences the second and third rockers of gait. Understanding these effects is crucial for optimizing gait in individuals post-stroke. This study investigated the impact of dorsiflexion ROM adjustments in multi-function articulated AFOs on ankle, knee, and hip kinematics during gait in individuals post-stroke. Nine participants were tested across six AFO settings, including three dorsiflexion ROM levels (0°, 5°, 10°) with two spring stiffness levels (low stiffness = 200 N/mm, high stiffness = 515 N/mm) of the Triple Action ankle joint. Kinematic data were collected using a 3D motion capture system, and joint angle parameters were analyzed throughout the gait cycle. The results showed that increasing dorsiflexion ROM significantly increased the maximum dorsiflexion angle of the ankle and decreased the maximum extension angle of the knee, with no significant effects on hip joint kinematics or walking speed. Increased ankle dorsiflexion facilitates tibial progression during the second rocker of gait, enhancing walking efficiency. However, the decrease in knee extension angle or increase in knee flexion angle may pose challenges to knee stability. This study suggests that dorsiflexion ROM of articulated AFOs should be tailored: individuals with stable knee joints may benefit from increased dorsiflexion ROM to optimize the second rocker, while those with unstable knees may require reduced dorsiflexion ROM to enhance stability.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"187 ","pages":"Article 112755"},"PeriodicalIF":2.4,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144069556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of collagen damage and failure mechanics in porcine pia-arachnoid complex","authors":"Emma Luke ,&nbsp;Brittany Coats","doi":"10.1016/j.jbiomech.2025.112745","DOIUrl":"10.1016/j.jbiomech.2025.112745","url":null,"abstract":"<div><div>Mild traumatic brain injury (mTBI) accounts for approximately 75% of all TBI cases, and the mechanisms are still poorly understood, in part due to limitations of current diagnostic tools. Yet, there is a critical need to detect the presence of mTBI to mitigate risk of further injury. In this study, we explore the potential of collagen hybridizing peptides (CHPs), which selectively bind to damaged collagen, to detect damage in the pia-arachnoid complex (PAC), a major load-transferring interface during head trauma. To generate damage, porcine PAC samples underwent peel tests. Peak force to failure and CHP fluorescence were measured in three regions of the brain at multiple post-mortem times. The peak force of PAC failure was region-specific, with increasing failure forces moving anterior to posterior (frontal: 20.91 ± 38.77 mN; parietal: 64.72 ± 33.31 mN; occipital: 86.68 ± 43.46 mN) and significantly different between frontal and occipital regions (p = 0.034). CHP fluorescence was significantly different between control and peeled PAC samples in mean pixel intensity (MPI; p = 0.031), median pixel intensity (MedPI; p = 0.009), and percent pixels above a defined threshold (PP; p = 0.014). Each of these CHP fluorescence metrics were significantly and positively correlated with peak force at failure (MPI: p = 0.049; MedPI: p = 0.026; PP: p = 0.002). These data suggest CHP is a viable solution to detecting the presence and severity of damage at the brain-skull interface, and may be a useful tool for quantifying damage in vivo.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"187 ","pages":"Article 112745"},"PeriodicalIF":2.4,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144069555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of pre-activation force on active force generation in skeletal muscle","authors":"Eng Kuan Moo ,&nbsp;Venus Joumaa ,&nbsp;Walter Herzog","doi":"10.1016/j.jbiomech.2025.112744","DOIUrl":"10.1016/j.jbiomech.2025.112744","url":null,"abstract":"<div><div>Cross bridges play a central role in skeletal muscle force generation. The level of force per cross bridge and the number of attached cross bridges are thought to determine muscle performance. Recent studies propose the so-called myosin-activation hypothesis, which suggests that stress exerted on myosin filaments increases the number of attached cross bridges and, hence, active force. This study was aimed at investigating the influence of passive stress magnitude exerted at the onset of activation on active force in a whole muscle preparation. The tibialis anterior (TA) muscle–tendon unit (MTU) of mice (N = 8) was stretched uniaxially <em>in situ</em> to long lengths where substantial viscoelastic passive force relaxation occurs. Muscle stress upon activation was varied by activating the TA either immediately at the end of the passive stretch (high passive force), or following nearly complete passive force relaxation (low passive force). Total forces with and without activation were measured from every MTU. Active forces were calculated by subtracting the passive force relaxation curve from the total force measured over a 1.13-s activation. We found that active force generated by the TA at low passive stress was 5–13 % higher than that at high passive stress. While the results seem contradictory to the myosin-activation hypothesis, we speculate that the results arose either from length adjustments between muscle and tendon during passive force relaxation, from excessive lattice spacing compression, or from unfavourable alterations of myosin conformation by high passive stress. Further research is required to improve our understanding of active force generation under the influence of viscoelasticity of muscle and tendon.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"186 ","pages":"Article 112744"},"PeriodicalIF":2.4,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143922182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Using Generic vs. Subject-Specific Muscle Properties on Spinal Load Prediction Across Different Posture Simulations","authors":"Nima Ashjaee ,&nbsp;Sidney Fels ,&nbsp;John Street ,&nbsp;Thomas Oxland","doi":"10.1016/j.jbiomech.2025.112741","DOIUrl":"10.1016/j.jbiomech.2025.112741","url":null,"abstract":"<div><div>Subject-specific musculoskeletal models hold promise for adult spinal deformity management. However, fully subject-specific models require subject-specific soft-tissue properties not typically available in clinical settings. Models created using generic properties are more accessible but potentially less accurate. The objective of this study was to identify which biomechanical properties of muscle function, and in which specific body positions, exhibit significant differences when implementing generic versus subject-specific properties.</div><div>Using OpenSim, we analyzed 250 subject-specific models, focusing on four muscle parameters: geometry-path, maximum-isometric-force, optimal-fiber-length, and tendon-slack-length across 11 postures, encompassing standing and flexed postures. A linear mixed-effects model evaluated the impact of muscle parameters on spinal compression loads. Differences in compression load between the models with subject-specific and generic data were compared statistically using non-parametric methods.</div><div>Subject-specific geometry-path and maximum-isometric-force significantly influenced spinal compression loads, with mean differences of 13 % and 8 %, respectively. Differences were posture-dependent (geometry-path <em>p</em> &lt; 0.001; max-isometric-force <em>p</em> = 0.005). Optimal-fiber-length (<em>p</em> = 0.053) and tendon-slack-length (<em>p</em> = 0.680) showed minimal impact (∼1% difference). Flexed postures were more sensitive to generic muscle parameters, with mean differences of 17 % (geometry-path) and 6 % (max-isometric-force), compared to standing (6 % and 4 %, respectively).</div><div>The pronounced deviations observed in flexion simulations emphasized the necessity of subject-specific data in such simulations. However, when subject-specific data is not available, simulations based on standing postures are the least affected by the use of generic properties.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"188 ","pages":"Article 112741"},"PeriodicalIF":2.4,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144123215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vertical displacement of the approximated body center of mass during typical daily activities: A transition-based complementary filter method using barometric and inertial data","authors":"Alessandra Audisio ,&nbsp;Daniele Fortunato ,&nbsp;Paolo Tasca,&nbsp;Marco Caruso,&nbsp;Andrea Cereatti","doi":"10.1016/j.jbiomech.2025.112711","DOIUrl":"10.1016/j.jbiomech.2025.112711","url":null,"abstract":"<div><div>By monitoring the movement of the body’s centre of mass during daily-living activities, it is possible to gather information on an individual’s functional capacity and quantify key abilities such as lower limb strength, postural control and dynamic stability. To this end, a wearable inertial measurement unit attached to the lower back can offer a practical solution for analysing CoM movement in real-world conditions. However, accelerometer-based measurements are prone to drift, limiting their suitability for long-term monitoring. To mitigate these effects, miniaturized high-resolution barometers can be integrated to provide stable direct height measurements. In this study, we developed and validated a method for the reconstruction of the vertical displacement of the centre of mass during daily activities (Transition-Based Complementary Filter). The method consisted of two steps: first, the transition intervals within which vertical displacements of the centre of mass occur are identified, then, within these intervals, the complementary filter is applied to estimate the vertical displacement. Validation was carried out on twenty healthy subjects wearing an inertial unit and a barometer on the lower back, while a marker-based stereophotogrammetry system served as reference. Participants performed a series of motor tasks replicating typical home-based activities, including standing, sitting, lying, squatting, and stair climbing. The method demonstrated high accuracy, achieving a median root mean square error of 0.02 m and a median concordance correlation coefficient of 98 %. These findings underscore its robustness and clinical utility, paving the way for improved rehabilitation strategies and enhanced patient outcomes.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"186 ","pages":"Article 112711"},"PeriodicalIF":2.4,"publicationDate":"2025-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143917724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of wider step-width gait on hip joint contact force","authors":"Lizheng Jiang ,&nbsp;Yoshitaka Iwamoto ,&nbsp;Shun Ezumi ,&nbsp;Yosuke Ishii ,&nbsp;Shunsuke Kita ,&nbsp;Makoto Takahashi","doi":"10.1016/j.jbiomech.2025.112742","DOIUrl":"10.1016/j.jbiomech.2025.112742","url":null,"abstract":"<div><div>Hip joint contact force (HJCF) overloading is a primary mechanical cause of hip osteoarthritis. Hip adduction moment (HAM) is a surrogate measure for estimating HJCF. Gait modification, especially wider step-width (SW), can significantly decrease the peaks and impulses of HAM, suggesting a possible strategy for preventing joint overloading. However, the effectiveness of a wider SW in directly reducing HJCF remains to be determined. In our study, fourteen healthy young participants comfortably walked with normal SW, double SW and triple SW. The neuromusculoskeletal simulation, calculation of HJCF peak values and impulse were carried out using Opensim during gait tasks. 3D motion capture system and surface electromyography assessed HAM peak values, impulse and muscle activities around the hip. Variations in HJCF, HAM, muscle activities, correlations between HJCF and HAM peaks were evaluated across walking conditions. We found that increasing the SW to double and triple significantly diminished the 2nd peaks and impulses of HJCF and HAM. Under the triple SW condition, the 1st peak of HAM notably decreased, whereas the activities of the gluteus medius and rectus femoris muscles markedly increased. Correlation analyses revealed that the 1st peak of HJCF was significantly associated with the 1st peak of HAM across all walking conditions. Moreover, the 2nd peak showed a significant correlation with both double and triple SW conditions. Increasing SW markedly improves dynamic HJCF, with changes in gluteus medius activity and HAM explaining this effect. This finding supports wider SW as a viable strategy for mitigating hip joint overload.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"186 ","pages":"Article 112742"},"PeriodicalIF":2.4,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143922181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}