Journal of biomechanics最新文献

{"title":"Data should be made as simple as possible but not simpler: The method chosen for dimensionality reduction and its parameters can affect the clustering of runners based on their kinematics","authors":"Adrian R Rivadulla ,&nbsp;Xi Chen ,&nbsp;Dario Cazzola ,&nbsp;Grant Trewartha ,&nbsp;Ezio Preatoni","doi":"10.1016/j.jbiomech.2024.112433","DOIUrl":"10.1016/j.jbiomech.2024.112433","url":null,"abstract":"<div><div>Dimensionality reduction is a critical step for the efficacy and efficiency of clustering analysis. Despite the multiple available methods, biomechanists have often defaulted to Principal Component Analysis (PCA). We evaluated two PCA- and one autoencoder-based dimensionality reduction methods for their data compression and reconstruction capability, assessed their effect on the output of clustering runners’ based on kinematics, and discussed their implications for the biomechanical assessment of running technique. Eighty-four participants completed a 4-minute run at 12 km/h while trunk and lower-limb kinematics were collected. Data reconstruction quality was assessed for Direct PCA (PCA directly on original variables) and Fourier PCA (modelling time series as Fourier series and then applying PCA) using popular variance explained criteria; and a feedforward autoencoder (AE). Agglomerative hierarchical clustering was then applied and the agreement between the resulting partitions was assessed. Meaningful errors in the reconstructed signals were found when applying popular variance explained criteria, suggesting reconstruction error should be assessed to make a more informed decision about how many components to retain for further analysis. Direct PCA, Fourier PCA and AE yielded different clusters, warranting caution when comparing outcomes from studies that use different dimensionality reduction techniques: each method may be sensitive to different data features. Direct PCA retaining 99 % of the original variance emerged as the best compromise of data compression, reconstruction quality and cluster separability in our dataset. We encourage biomechanists to experiment with diverse dimensionality reduction methods to optimise clustering outcomes and enhance the real-world applicability of their findings.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"177 ","pages":"Article 112433"},"PeriodicalIF":2.4,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142687083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peak hip external rotation torque and single-rater reliability is influenced by measurement position in the ISOMED2000","authors":"Christina Frese ,&nbsp;Tobias Siebert ,&nbsp;Dieter Bubeck ,&nbsp;Iris Astner ,&nbsp;Daniel Sitte ,&nbsp;Wilfried Alt","doi":"10.1016/j.jbiomech.2024.112430","DOIUrl":"10.1016/j.jbiomech.2024.112430","url":null,"abstract":"<div><div>Measurement of hip external rotation strength (ERS) is important for preventive and rehabilitative purposes. ERS can be measured in 3 different positions in the isokinetic dynamometer ISOMED2000. However, it is not clear whether these measurement positions effect ERS nor if these positions are reliable in the ISOMED2000. Hence, the purpose of this study was to compare ERS in these positions, the reliability and the agreement. A cross-sectional design was conducted to compare measurement positions and a test–retest design to assess intra-rater reliability and agreement. Twenty-four healthy, physically active athletes participated in the study. Peak isometric torque was measured in the ISOMED in prone, supine, and side-lying position across two sessions on one day. Differences between positions were evaluated with the Wilcoxon-signed-rank test and cliff’s delta. Reliability was assessed via intraclass correlation. Agreement was determined using the standard error of measurement (SEM), minimal detectable change (MDC), and Bland-Altman analysis (BAA). Results indicated a significant influence of measurement position on ERS (p &lt; 0.001) with high effect sizes (&gt;0.74). Reliability and agreement were high in all positions, but highest for the side-lying position (ICC = 0.90 [0.78, 0.96]; SEM = 0.08; MDC = 0.23; BAA_bias = 3.4 %, BAA_loA = 37 %). There were only poor to moderate correlations between measurement positions. These findings suggest that measurement position significantly affects ERS. Furthermore, the effect varies across individuals indicating that normative values cannot be used interchangeably or be adapted across positions. In diagnostic testing ERS should be measured in the same position, but preferably in the side-lying position.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"177 ","pages":"Article 112430"},"PeriodicalIF":2.4,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142692966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myofascial force transmission between latissimus dorsi and contralateral gluteus maximus in runners: a cross-sectional study","authors":"Paola Figueiredo Caldeira ,&nbsp;Renan Alves Resende ,&nbsp;Bárbara Junqueira Murta ,&nbsp;Robert Schleip ,&nbsp;Paula Renata Soares Procópio ,&nbsp;Priscila Albuquerque Araújo ,&nbsp;Sérgio Teixeira Fonseca ,&nbsp;Juliana Melo Ocarino","doi":"10.1016/j.jbiomech.2024.112431","DOIUrl":"10.1016/j.jbiomech.2024.112431","url":null,"abstract":"<div><div>The anatomical connection between latissimus dorsi (LD), thoracolumbar fascia, and contralateral gluteus maximus (GM) enables myofascial force transmission (MFT) between the shoulder, trunk, and hip. This study investigates whether regular sports practice, specifically running, influences this MFT pathway. Given the potential changes in tissue stiffness from sports practice and the importance of this property for MFT, we hypothesize that runners may exhibit greater MFT between the LD and GM, resulting in altered passive properties of the lumbar and hip regions during LD contraction. This study aimed to investigate whether runners present a higher modification in lumbar stiffness and passive properties of the contralateral hip due to LD contraction than sedentary individuals. The lumbar stiffness, hip resting position, passive hip torque, and stiffness of fifty-four individuals were assessed using an indentometer and an isokinetic dynamometer, respectively, in two conditions: LD relaxed, and LD contracted. The main and interaction effects were assessed using a two-way ANOVA. The LD contraction increased lumbar stiffness (p &lt; 0.001; η_p² = 0.50), externally rotated the hip resting position and increased the passive hip torque and stiffness (p &lt; 0.05; η_p² &gt; 0.1) in both groups. In addition, runners presented higher lumbar stiffness compared to sedentary in the LD contracted condition (p = 0.017, ES_d = 0.54). Although runners exhibited increased lumbar stiffness during LD contraction, the MFT from the shoulder to the hip joint occurred similarly in both groups.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"177 ","pages":"Article 112431"},"PeriodicalIF":2.4,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142655410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in lower extremity muscle coordination over a 30-minute walk do not differ by muscle fatigability","authors":"Jocelyn F. Hafer ,&nbsp;Sarah A. Roelker ,&nbsp;Katherine A. Boyer","doi":"10.1016/j.jbiomech.2024.112434","DOIUrl":"10.1016/j.jbiomech.2024.112434","url":null,"abstract":"<div><div>Muscle fatigue, the transient decrease in muscle power, leads to low levels of physical activity and an inability to perform activities of daily living. Altered muscle coordination in response to fatigue may contribute to impaired physical performance. We sought to determine whether lower extremity muscle coordination during gait changes differently depending on susceptibility to fatigue (i.e., fatigability). Thirty-one older adults completed muscle power testing before and after a 30-min walk, with the change in power used to categorize participants as more or less fatigable. We used non-negative matrix factorization to identify muscle modules from electromyography (EMG) from the 2nd minute as our measure of baseline muscle coordination. Changes in muscle coordination were determined by computing the <em>variance</em> in the 30th minute’s EMG <em>accounted for</em> by the baseline modules across all muscles (tVAF) and in individual muscles (mVAF). We compared tVAF between the 2nd and 30th minutes of the walk in individuals who were more and less fatigable. We used mVAF to explore the contribution of changes in individual muscle activity to tVAF. There was a decrease in tVAF overall in response to the walk (p &lt; 0.001; 92.3 ± 1.6 % vs. 89.0 ± 4.3 %) but this did not differ between groups (interaction p = 0.66). There were significant associations between mVAF and tVAF for knee extensor, knee flexor, and ankle dorsiflexor muscles. Our results suggest that muscle coordination changes over the course of a walk in older adults but that this change does not differ between more and less fatigable older adults.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"177 ","pages":"Article 112434"},"PeriodicalIF":2.4,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142655409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient-specific, multiscale modelling of neointimal hyperplasia in lower-limb vein grafts using readily available clinical data","authors":"Federica Ninno ,&nbsp;Claudio Chiastra ,&nbsp;Francesca Donadoni ,&nbsp;Alan Dardik ,&nbsp;David Strosberg ,&nbsp;Edouard Aboian ,&nbsp;Janice Tsui ,&nbsp;Stavroula Balabani ,&nbsp;Vanessa Díaz-Zuccarini","doi":"10.1016/j.jbiomech.2024.112428","DOIUrl":"10.1016/j.jbiomech.2024.112428","url":null,"abstract":"<div><div>The prediction of neointimal hyperplasia (NIH) growth, leading to vein graft failure in lower-limb peripheral arterial disease (PAD), is hindered by the multifactorial and multiscale mechanobiological mechanisms underlying the vascular remodelling process. Multiscale <em>in silico</em> models, linking patients’ hemodynamics to NIH pathobiological mechanisms, can serve as a clinical support tool to monitor disease progression. Here, we propose a new computational pipeline for simulating NIH growth, carefully balancing model complexity/inclusion of mechanisms and readily available clinical data, and we use it to predict NIH growth for an entire vein graft. To this end, three different fittings to published <em>in vitro</em> data of time-averaged wall shear stress (TAWSS) vs nitric oxide (NO) production were tested for predicting long-term graft response (10-month follow-up) on a single patient. Additionally, the sensitivity of the model’s predictions to different inflow boundary conditions (BCs) was assessed. The main findings indicate that: (i) a TAWSS-NO hyperbolic relationship best predicts long-term graft response; (ii) the model is insensitive to the inflow BCs if the waveform shape and the systolic acceleration time are comparable with the one acquired at the same time as the computed-tomography scan. This proof-of-concept study demonstrates the potential of using multiscale, computational techniques to predict NIH growth in lower-limb vein grafts, considering the routine clinical scenario of non-standardised data collection and sparse, incomplete datasets.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"177 ","pages":"Article 112428"},"PeriodicalIF":2.4,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomechanical evaluation of the porcine carpus as a potential preclinical animal model for the human carpus","authors":"Madison K. Altieri ,&nbsp;Rohit Badida ,&nbsp;Quianna M. Vaughan ,&nbsp;Janine Molino ,&nbsp;Edward Akelman ,&nbsp;Joseph J. Crisco","doi":"10.1016/j.jbiomech.2024.112429","DOIUrl":"10.1016/j.jbiomech.2024.112429","url":null,"abstract":"<div><div>Advancing successful treatments for carpal instabilities of the wrist are hindered due, in part, to limited preclinical animal models. The purpose of this study was to evaluate the forelimb of the Yucatan minipig (YP) as a potential preclinical animal model for the human wrist by quantifying carpal biomechanics <em>in vitro</em> in the intact and after two ligament transection conditions. Porcine wrist biomechanics (n = 12, 5M, 7F) were determined in 28 range of motion (ROM) directions, in pronation-supination, and in volar-dorsal translation using a six-axis robotic musculoskeletal simulator. Testing was implemented in three conditions – intact, and after sequential transection of the radial intermediate ligament (RIL) and the dorsal intercarpal ligament (DIC). Mixed models were employed to examine differences in direction and conditions among male and female specimens. The intact ROM envelope was elliptical in shape and oriented toward ulnar flexion with the largest ROM about 15° from the flexion–extension axis. Transection of RIL and DIC did not alter the ROM envelope orientation, however, subtle increases in ROM were observed in extension and radial deviation following transection of both RIL and DIC. Pronation in neutral was greater than supination in all three test conditions. Volar translation increased subtly in the RIL and DIC condition. This novel study investigated the multidirectional biomechanics of the YP forelimb. ROM in the general directions of extension, radial and ulnar deviation were less than in humans, while flexion was substantially larger. These specific ligament transections had minor effects on the biomechanics of the YP forelimb.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"177 ","pages":"Article 112429"},"PeriodicalIF":2.4,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Image-based finite element model stiffness and vBMD by single and dual energy CT reconstruction kernel","authors":"Nikolas K. Knowles,&nbsp;Sarah Quayyum,&nbsp;Jonathan Ying,&nbsp;Chloe Stiles,&nbsp;Daniel Beshay","doi":"10.1016/j.jbiomech.2024.112426","DOIUrl":"10.1016/j.jbiomech.2024.112426","url":null,"abstract":"<div><div>Single-energy quantitative computed tomography (SEQCT) provides volumetric bone mineral density (vBMD) measures for bone analysis and input to image-based finite element models (FEMs). Dual-energy CT (DECT) improves vBMD by accounting for voxel-specific material variations utilizing scans at multiple x-ray energies. vBMD is also altered by reconstruction kernel that cannot be accounted for using calibration phantoms. This study compared vBMD and FEM stiffness derived from SEQCT and DECT images reconstructed with two common kernels. SEQCT and DECT images of cadaveric shoulders (n = 10) were collected using standard (STD) and boneplus (BONE) kernels. Hounsfield Units were converted to vBMD using specimen-specific calibrations. DECT STD and BONE images were generated using an established material decomposition method with 40 and 90 keV simulated monochromatic images. A proximal humerus bone section below the anatomic neck was used for vBMD analysis and FEM generation. FEMs were loaded to 1% apparent strain for stiffness measurements.</div><div>Between STD and BONE kernel images, average vBMD differed 0.9 mg_K2HPO4/cc and 4.1 mg _K2HPO4/cc, in SEQCT and DECT images, respectively. Significant differences occurred in DECT images (p = 0.001). BONE reconstructed images produced higher vBMD measures across both SEQCT and DECT images. The difference between STD and BONE in both SEQCT- and DECT-based FEMs persisted, with larger estimated stiffness in BONE models. For six of the models DECT-based had higher stiffness than SEQCT-based models using the same kernel, although these models differed between STD and BONE kernels. Differences in stiffness between STD and BONE derived models were similar across image types (DECT: 17.5 kN/mm; SEQCT: 19.0 kN/mm). Stiffness values were significantly different within SECT kernels and between SEQCT BONE and DECT STD models. This study shows important differences in vBMD and FEM stiffness that occur due to CT-based imaging parameters alone. These results indicate that consistent imaging parameters should be used for vBMD analysis and FEM input to avoid systematic measurement errors.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"177 ","pages":"Article 112426"},"PeriodicalIF":2.4,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142621115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of joint angle positioning on shearwave speed and variability with ultrasound shearwave elastography in asymptomatic Achilles and patellar tendons","authors":"Rachana Vaidya ,&nbsp;Stephane Cui ,&nbsp;Bryson Houston ,&nbsp;Andrew North ,&nbsp;Menghan Chen ,&nbsp;Josh Baxter ,&nbsp;Jennifer A. Zellers","doi":"10.1016/j.jbiomech.2024.112427","DOIUrl":"10.1016/j.jbiomech.2024.112427","url":null,"abstract":"<div><div>This study investigated the impact of joint positioning on ultrasound shear wave elastography measurements in the Achilles and patellar tendons. Twenty-eight healthy adults underwent SWE assessment of shear wave speed (SWS) and coefficient of variation in SWS (CV-SWS) at three ankle positions (neutral, 10° plantar flexion, and 20° dorsiflexion) and two knee positions (90° flexion and full extension), at two academic sites. Participant positioning for ankle testing differed between sites (prone vs long-sitting)—while knee testing used consistent positioning. At the ankle, both joint and participant positioning significantly affected SWS. In the prone position, SWS was lower in neutral compared to dorsiflexed position (3.07 ± 1.13  m/s vs. 3.95 ± 1.03  m/s, p = 0.013). In long-sitting, SWS was lower in neutral compared to plantarflexed position (2.85 ± 0.53  m/s vs. 4.86 ± 1.92  m/s, p = 0.016); and SWS was higher in the plantarflexed position when participants were in long-sitting compared to prone (4.86 ± 1.92  m/s vs. 3.25 ± 1.13  m/s, p = 0.016). Participant positioning affected CV-SWS, with higher variability observed in prone compared to long-sitting in plantarflexed (29.3 ± 15.5 % vs 12.4 ± 9.12 %, p = 0.005) and neutral ankle angles (p = 0.03).</div><div>At the knee, joint position significantly influenced SWS, with higher values in flexed versus extended positions (6.48 ± 3.1  m/s vs. 4.60 ± 2.3  m/s, p = 0.007). Extending the knee reduced CV-SWS compared to flexed position (14.5 ± 11.2 vs 19.2 ± 13.4, p = 0.044). In conclusion, joint position significantly affected SWS measurements in both the Achilles and patellar tendons, while participant positioning influenced measurement variability. Thus, standardizing joint and participant positioning is important to enhance the reliability of SWE assessments of tendon elasticity.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"177 ","pages":"Article 112427"},"PeriodicalIF":2.4,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Levodopa-induced dyskinesia alters postural control in people with Parkinson’s disease","authors":"Joseph Ayotunde Aderonmu,&nbsp;Carolin Curtze","doi":"10.1016/j.jbiomech.2024.112421","DOIUrl":"10.1016/j.jbiomech.2024.112421","url":null,"abstract":"<div><div>While levodopa is the most effective drug for symptom treatment of Parkinson’s Disease (PD), its long-term use often leads to side effects such as uncontrolled involuntary movements known as levodopa-induced dyskinesia (LID). LID has been shown to increase postural sway, but the extent to which these hyperkinetic movements alter postural sway strategies has not been explored. We recruited 25 people with idiopathic PD, of which 13 exhibit clinical signs of LID, and 10 healthy older adults. Participants performed thirty-second standing trials with no added task (single-task) and with performing a cognitive dual-task, known to provoke dyskinesia. Participants with PD were tested in their practical OFF and ON states. The root-means-square (RMS) accelerations were obtained from inertial sensors attached to the lumbar, trunk, and head. Sway ratios (superior-to-inferior segment) were calculated to determine the effect of LID on postural sway strategies. Participants with LID showed greater RMS head sway, compared to those without LID and older adults. The head-to-trunk sway ratio was greater in participants with LID during the ON state or when dual-tasking. In addition, the head-to-lumbar sway ratio was greater in participants with LID in the ON state during both single- and dual-tasking. Our results reveal an altered postural control strategy in PD with LID, presenting increased sway in superior segments of the kinematic chain, leading to head instability. Unlike PD without LID and older adults, PD with LID exhibit multi-link sway in the ON state, which has important implications for measuring postural sway in the presence of dyskinesias.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"177 ","pages":"Article 112421"},"PeriodicalIF":2.4,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142721474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paradoxıcal effect of body mass index ranges on pedobarographic evaluatıon","authors":"Açıkgöz Tahsin ,&nbsp;Nur Kakilli ,&nbsp;Çiftdemir Mert ,&nbsp;Ekuklu Galip ,&nbsp;Nurettin Taştekin","doi":"10.1016/j.jbiomech.2024.112419","DOIUrl":"10.1016/j.jbiomech.2024.112419","url":null,"abstract":"<div><div>Although there is evidence suggesting that obesity alters plantar pressure distribution, the specific effects of certain body mass index (BMI) ranges on pedobarographic measures in healty individuals has been poorly investigated. A cross-sectional study with 167 healthy participants was conducted to assess plantar pressure changes across 4 BMI ranges: Under/normal weight (NW), overweight (OW), obese (OB), severe obese (SO). Subjects walked on the Footscan® pressure plate at a self-selected speed, and peak plantar pressure (PPP), load rate, and contact area values were recorded. The foot was divided into 10 zones: hallux (T1), toes 2–5 (T2-5), metatarsals 1–5 (M1-M5), midfoot (MF), medial hindfoot (MH) and lateral hindfoot (LH). PPP underneath M2-M4 was lowest in the NW group (p = 0.011), and although PPP values for the SO group were lower than those for the OW and OB groups, these differences were not statistically significant. Load rate values of M2-M3 were lower in both the NW and SO groups (p = 0.008) compared to the OW and OB groups. In addition, the metatarsal load rate values for the SO group were generally lower than those for the NW group. The total metatarsal contact area of both the NW and SO groups was lower (p = 0.019) than that of the OW and OB groups in both feet. These findings suggest that as BMI increases, PPP, load rate, and contact area in the middle metatarsal region initially increase, stabilize early in obesity, and then decrease at advanced stages, indicating a shift of the load to the midfoot.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"177 ","pages":"Article 112419"},"PeriodicalIF":2.4,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142621116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}