基于高斯基函数的垂直地面反作用力的生理约束分解:步态表征的全曲线方法

IF 2.4 3区 医学 Q3 BIOPHYSICS
Thomas Ertelt
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引用次数: 0

摘要

我们的目的是测试健康衍生的相位锚定μ模板是否可以近似病理vGRF波形,并量化相对于规范模式的偏差。传统的基于峰值的度量方法只能捕捉到步态动力学的片段。本研究引入了一种生理锚定模型,该模型用八个高斯基函数重建了整个垂直地面反力(vGRF)曲线,每个函数都与姿态的特定子阶段相关联。91条已发表的vGRF轨迹代表了健康的步行和跑步、中风后恢复阶段、全髋关节置换术后的步态、经胫骨和足假体的使用以及运动员短跑,这些轨迹被数字化、幅度和时间归一化,并采用约束非线性优化进行拟合。位置参数(μ)被限制在相位平均值周围±1个标准差范围内,而振幅(A)和宽度(σ)可以自由优化。该模型重现了所有条件下的GRF形态,决定系数(R2)在0.95 ~ 0.99之间,均方根误差小于0.03体重。固定μ值单独重建参考行走曲线,R2 = 0.996,验证了相位模板的有效性。A和σ的雷达图可视化显示了在基于峰值的分析中被掩盖的特征偏差:卒中后步态中站立负荷升高和推离减少,髋关节置换术后中站立分量变宽,假肢中站立后幅度减弱。八分量高斯模型提供了vGRF轨迹的简明24参数表示,实现了准确、可解释和高效存储的步态分析。它的相位固定结构提高了诊断灵敏度,支持康复过程监测,并且易于转移到可穿戴或大规模数据库应用中。雷达图提供了步态形态的探索性总结,支持个体内部和个体之间的客观比较。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Physiologically-constrained decomposition of vertical ground reaction forces using gaussian basis functions: A full-curve approach to gait characterization
We aimed to test whether a healthy-derived, phase-anchored μ template can approximate pathological vGRF waveforms and quantify deviations relative to normative patterns. Traditional peak-based metrics capture only fragments of gait dynamics. This study introduces a physiologically anchored model that reconstructs the entire vertical ground-reaction-force (vGRF) curve with eight Gaussian basis functions, each linked to a specific sub-phase of stance. Ninety-one published vGRF traces representing healthy walking and running, post-stroke recovery stages, total-hip-arthroplasty gait, transtibial and foot-prosthesis use, and athletic sprinting were digitised, amplitude- and time-normalised, and fitted with constrained non-linear optimisation. Position parameters (μ) were restricted to ± 1 standard deviation around phase-specific mean values, while amplitudes (A) and widths (σ) were freely optimised. The model reproduced GRF morphology with coefficients of determination (R2) from 0.95 to 0.99 and root-mean-square errors below 0.03 body-weight across all conditions. Fixed μ values alone reconstructed a reference walking curve with R2 = 0.996, demonstrating the validity of the phase template. Radar plot visualisations of A and σ revealed characteristic deviations that were obscured in peak-based analysis: elevated mid-stance loads and diminished push-off in post-stroke gait, broadened mid-stance components after hip arthroplasty, and attenuated late-stance amplitudes in prosthetic limbs. The eight-component Gaussian model provides a concise 24-parameter representation of vGRF trajectories, enabling accurate, interpretable and storage-efficient gait profiling. Its phase-anchored structure enhances diagnostic sensitivity, supports progress monitoring in rehabilitation, and is readily transferable to wearable or large-scale database applications. Radar plots offer an exploratory summary of gait morphology, supporting objective comparisons within and between individuals.
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来源期刊
Journal of biomechanics
Journal of biomechanics 生物-工程:生物医学
CiteScore
5.10
自引率
4.20%
发文量
345
审稿时长
1 months
期刊介绍: The Journal of Biomechanics publishes reports of original and substantial findings using the principles of mechanics to explore biological problems. Analytical, as well as experimental papers may be submitted, and the journal accepts original articles, surveys and perspective articles (usually by Editorial invitation only), book reviews and letters to the Editor. The criteria for acceptance of manuscripts include excellence, novelty, significance, clarity, conciseness and interest to the readership. Papers published in the journal may cover a wide range of topics in biomechanics, including, but not limited to: -Fundamental Topics - Biomechanics of the musculoskeletal, cardiovascular, and respiratory systems, mechanics of hard and soft tissues, biofluid mechanics, mechanics of prostheses and implant-tissue interfaces, mechanics of cells. -Cardiovascular and Respiratory Biomechanics - Mechanics of blood-flow, air-flow, mechanics of the soft tissues, flow-tissue or flow-prosthesis interactions. -Cell Biomechanics - Biomechanic analyses of cells, membranes and sub-cellular structures; the relationship of the mechanical environment to cell and tissue response. -Dental Biomechanics - Design and analysis of dental tissues and prostheses, mechanics of chewing. -Functional Tissue Engineering - The role of biomechanical factors in engineered tissue replacements and regenerative medicine. -Injury Biomechanics - Mechanics of impact and trauma, dynamics of man-machine interaction. -Molecular Biomechanics - Mechanical analyses of biomolecules. -Orthopedic Biomechanics - Mechanics of fracture and fracture fixation, mechanics of implants and implant fixation, mechanics of bones and joints, wear of natural and artificial joints. -Rehabilitation Biomechanics - Analyses of gait, mechanics of prosthetics and orthotics. -Sports Biomechanics - Mechanical analyses of sports performance.
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