Japanese Journal of Ophthalmology最新文献

{"title":"Outcomes, efficacy and risk factors of 27-Gauge vitrectomy for diabetic tractional retinal detachment in Japanese patients.","authors":"Risa Nishigushi, Ayumi Usui-Ouchi, Yoshihito Sakanishi, Kazunori Tamaki, Keitaro Mashimo, Rei Ito, Toshiro Sakuma, Nobuyuki Ebihara, Shintaro Nakao","doi":"10.1007/s10384-024-01135-6","DOIUrl":"10.1007/s10384-024-01135-6","url":null,"abstract":"<p><strong>Purpose: </strong>Diabetic retinopathy leads to vision-threatening complications, such as proliferative diabetic retinopathy and tractional retinal detachment (TRD) and is a major global health concern. Despite advancements in vitrectomy techniques, challenges exist in managing postoperative complications and long-term visual acuity. This study aimed to evaluate postoperative outcomes of 27-gauge pars plana vitrectomy (27 g PPV) for diabetic TRD and identify associated risk factors.</p><p><strong>Study design: </strong>Retrospective study.</p><p><strong>Methods: </strong>This study included 94 eyes of 74 patients who underwent 27 g PPV for diabetic TRD between July 2017 and September 2022 at Juntendo University Urayasu Hospital, Japan. Patient demographics, preoperative characteristics, intraoperative details, and postoperative outcomes were examined. Statistical analyses were performed to identify factors influencing postoperative visual acuity.</p><p><strong>Results: </strong>Mean follow-up duration was 23.1 ± 14.6 months. Postoperatively, visual acuity (LogMAR) improved significantly from 1.34 ± 0.82 to 0.65 ± 0.79 (P < 0.0001). Postoperative complications included persistent vitreous hemorrhage (15%) and neovascular glaucoma (4%). Final retinal reattachment rate was 97%. Preoperatively, macular detachment (P < 0.0001) and Grade IV TRD (P < 0.0001) severity were significantly associated with poor final best corrected visual acuity (P < 0.0001). Preoperative macular detachment (P < 0.0001), Grade IV TRD (P < 0.0001), intraoperative iatrogenic breaks (P = 0.031), and postoperative neovascular glaucoma (P < 0.0001) were identified as significant predictors of poor postoperative visual outcomes through multivariate analysis.</p><p><strong>Conclusion: </strong>This study highlights the efficacy of 27 g PPV in improving visual acuity in patients with diabetic TRD. Despite favorable outcomes, attention to preoperative risk factors and meticulous surgical techniques remain crucial for optimizing long-term visual prognosis in these patients.</p>","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":"59-65"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11821670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142582795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical outcomes after trabeculotomy for primary congenital glaucoma.","authors":"Ayaka Edo, Kazuyuki Hirooka, Hideaki Okumichi, Asayo Yoshinaka, Shintaro Kohno, Yoshiaki Kiuchi","doi":"10.1007/s10384-024-01152-5","DOIUrl":"10.1007/s10384-024-01152-5","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate outcomes after trabeculotomy in Japanese patients with primary congenital glaucoma (PCG), and to identify risk factors for multiple glaucoma surgery procedures.</p><p><strong>Study design: </strong>Retrospective observational study.</p><p><strong>Methods: </strong>Surgical outcomes were investigated in Japanese patients with PCG who underwent their first glaucoma surgery at Hiroshima University Hospital between January, 2006, and December, 2021. The data included in this study were divided into single- and multiple-surgery groups, and risk factors for requiring multiple surgery procedures were evaluated using multivariate analysis.</p><p><strong>Results: </strong>Twenty eyes of 20 patients were included. All eyes underwent ab externo trabeculotomy as the first surgery. The mean follow-up period was 75.7 ± 44.8 months. The cumulative success rate for up to 3 trabeculotomies at 5 years after the first surgery was 89.7%. The glaucoma in 11 eyes (55.0%) was controllable with just one surgery, whereas 9 eyes (45.0%) required 2 or more glaucoma surgical procedures. The single-surgery group had a significantly better mean best-corrected visual acuity at the last visit than the multiple-surgery group (0.1 ± 0.1 versus 0.9 ± 1.1, respectively, p = 0.001) and a smaller mean cylindrical power (- 0.8 ± 0.8 versus - 2.2 ± 1.0, respectively, p = 0.01). In multivariate logistic analysis, a 1-mm increase in corneal diameter was associated with a 16-fold increase in the risk of multiple glaucoma surgical procedures (p = 0.047).</p><p><strong>Conclusion: </strong>The glaucoma in most PCG eyes can be controlled with up to three trabeculotomies. Corneal-diameter enlargement was a significant risk factor for multiple surgical procedures.</p>","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":"123-130"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143032684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2021 trends in the treatment of patients with strabismus in Japan.","authors":"Keiko Kunimi, Toshiaki Goseki, Sachiko Nishina, Takashi Negishi, Miho Sato","doi":"10.1007/s10384-024-01144-5","DOIUrl":"10.1007/s10384-024-01144-5","url":null,"abstract":"<p><strong>Purpose: </strong>To clarify the actual status of strabismus surgery and botulinum toxin (BTX) therapy in Japan in the year 2021.</p><p><strong>Study design: </strong>Cross-sectional study.</p><p><strong>Methods: </strong>We conducted a national survey of strabismus treatment in 2021 using a questionnaire consistent with a previous 2013 survey, incorporating additional questions about BTX therapy.</p><p><strong>Results: </strong>Among the 378 responding institutions, strabismus surgery or BTX therapy, or both, was performed at 185 institutions (49%; total cases, 10,767). In 151 (40%), 32 (8%), and 2 (1%) institutions, surgery only, surgery and BTX therapy, and BTX therapy only were performed, respectively. The distribution of institutions where strabismus surgery was performed consisted of 4 prefectures, accounting for 48% of the total, whereas no strabismus surgery was performed at any institution in 3 prefectures. Although the highest percentage of patients (23%) was aged between 10 and 19 years, 48.2% of the patients were aged 20 years or older, and 17% of them were aged 60 years or older. Exotropia (XT) was the most common type of strabismus (55%) followed by esotropia (ET) (24%). In terms of complex surgeries, 80.2% (more than 100 cases) were performed at institutions with more than 100 cases. Of the 34 institutions where BTX therapy was performed, 52% were performed at a single institution, and 18% were performed at 2 institutions where no strabismus surgery was performed. Patients with scarring in the extraocular muscles, such as thyroid eye disease, were the most treated, followed by those with ET, who were mainly given injection treatment.</p><p><strong>Conclusion: </strong>Institutions where strabismus surgery and BTX therapy could be performed were concentrated and limited.</p>","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":"10-16"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11821698/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the transscleral removal technique for subretinal proliferative tissues during vitrectomy for rhegmatogenous retinal detachment.","authors":"Tomoyuki Ishibashi, Ryo Inoue, Hiroshi Nakashima, Kazuyuki Emi","doi":"10.1007/s10384-024-01143-6","DOIUrl":"10.1007/s10384-024-01143-6","url":null,"abstract":"<p><strong>Purpose: </strong>To provide insights into the transscleral removal technique for subretinal proliferative tissues (SRP).</p><p><strong>Study design: </strong>Retrospective, single-center case series.</p><p><strong>Methods: </strong>Patients who underwent transscleral removal of SRP during vitrectomy for rhegmatogenous retinal detachment (RRD) were included. The preoperative RRD extent, SRP distribution, intraoperative maneuvers, complications, and surgical outcomes were assessed.</p><p><strong>Results: </strong>Seven eyes of seven patients were enrolled for surgery. The RRD extent involved four quadrants in two eyes, three quadrants in three eyes, and two quadrants in the remaining two eyes. SRP were widely distributed beneath the detached retina in all the cases, with submacular SRP present in six cases. In these six cases, all the SRP, including the submacular SRP, could be removed without creating retinotomies via 1 or 2 subretinal trocars. However, peripheral SRP with extensive and strong adhesion to the retina required multiple retinotomies and conventional bimanual removal in one case. Surgical failure, attributable to the transscleral technique, occurred in one case due to a missed retinal puncture that occurred during subretinal trocar insertion, resulting in recurrent RRD. This patient had RRD within two quadrants, and the subretinal space could not be adequately dilated before insertion. All the patients had achieved retinal reattachment without deterioration of visual acuity at the final follow-up visit.</p><p><strong>Conclusion: </strong>The transscleral removal technique was suitable for the removal of SRP, including the posterior pole area, with minimal retinal damage. However, this technique may not be appropriate for SRP removal with extensive and strong adhesions or for cases with relatively nonextensive RRD.</p>","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":"66-73"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First-year real-world experience of intravitreal brolucizumab injection for refractory neovascular age-related macular degeneration.","authors":"Jeong Hyun Lee, Joo Young Shin, Jeeyun Ahn","doi":"10.1007/s10384-024-01134-7","DOIUrl":"10.1007/s10384-024-01134-7","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the first-year real-world anatomical and functional outcomes of intravitreal brolucizumab injection in eyes with refractory neovascular age-related macular degeneration (nAMD).</p><p><strong>Study design: </strong>Retrospective observational study.</p><p><strong>Methods: </strong>nAMD patients who showed poor response to previous anti-vascular endothelial growth factor (VEGF) agents were switched to brolucizumab. Functional and anatomical outcomes were evaluated at initial treatment of nAMD, after treatment with other anti-VEGF agents and after switching and treating with brolucizumab for 1 year. Safety profile was also evaluated after brolucizumab injection. Best-corrected visual acuity (BCVA), central foveal thickness (CFT), subfoveal choroidal thickness (SFCT), and the presence of fluid in different compartments (intraretinal fluid [IRF], subretinal fluid [SRF], pigment epithelial detachment [PED]) were assessed at each time point.</p><p><strong>Results: </strong>A total of 40 eyes of 40 patients were included in the study. BCVA remained unchanged throughout treatment (p > 0.05). CFT did not change after treatment with other anti-VEGF agents (p = 0.588) but decreased after switching to brolucizumab (p < 0.001). SFCT decreased after treatment with other anti-VEGF agents (p = 0.025) but not after switching to brolucizumab (p = 0.236). Presence of SRF (p = 0.001) and PED (p = 0.001) decreased significantly after switching to brolucizumab, despite their persistence with prior treatments using other anti-VEGF agents. However, IRF persisted even after switching to brolucizumab (p = 0.745). Intraocular inflammation (IOI)-related adverse events were reported in 3 eyes (7.14%).</p><p><strong>Conclusion: </strong>Analysis of first-year real-world outcomes after switching to brolucizumab in nAMD patients refractory to other anti-VEGF agents showed improved anatomic outcomes, limited functional improvement and low incidence of IOI-related adverse events.</p>","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":"43-48"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11821690/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142575955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical outcomes of non-fovea-sparing internal limiting membrane peeling using a double-staining technique for symptomatic myopic foveoschisis: a retrospective study.","authors":"Tadashi Mizuguchi, Masayuki Horiguchi, Atsuhiro Tanikawa, Yasuki Ito","doi":"10.1007/s10384-024-01158-z","DOIUrl":"10.1007/s10384-024-01158-z","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the incidence of postoperative macular hole (MH), visual acuity, and anatomical recovery in patients who underwent a non-fovea-sparing technique using a double-staining method for symptomatic myopic foveoschisis without pre-existing macular holes.</p><p><strong>Study design: </strong>A retrospective study.</p><p><strong>Methods: </strong>We evaluated 39 eyes from 39 consecutive patients diagnosed with myopic foveoschisis from May 2017 to September 2022 at Fujita Health University Hospital. All patients underwent non-fovea-sparing internal limiting membrane peeling using a double-staining method and were monitored for 6 months postoperatively. Best-corrected visual acuity (BCVA) as measured by the logarithm of the minimum angle of resolution (logMAR), central retinal thickness (CRT), and the presence of foveoschisis were assessed using optical coherence tomography (OCT) preoperatively (pre) and at 1 month (1 M), 3 months (3 M), and 6 months (6 M) postoperatively.</p><p><strong>Results: </strong>No cases of postoperative rhegmatogenous retinal detachment were observed. A postoperative MH developed in one eye. The mean logMAR values at pre, 1 M, 3 M, and 6 M were 0.38 ± 0.37, 0.23 ± 0.33, 0.18 ± 0.25, and 0.13 ± 0.29, respectively (all P < 0.001). The mean CRTs at pre, 1 M, 3 M, and 6 M were 384.6 ± 177.2, 262.2 ± 84.4, 200.3 ± 64.9, and 185.6 ± 61.0 μm, respectively (all P < 0.001). Foveoschisis was observed in all 39 eyes (100%) preoperatively and in 17 eyes (43.6%) at 1 M, nine eyes (34.6%) at 3 M, and zero eyes (0%) at 6 M postoperatively.</p><p><strong>Conclusion: </strong>The non-fovea-sparing double-staining technique was effective in treating myopic foveoschisis without MH, leading to significant improvements in both visual function and anatomical recovery. This method may be a promising surgical option for managing myopic foveoschisis.</p>","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":"74-80"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modulation of the peak velocities and gains of abduction and adduction saccades according to head position.","authors":"Hana Mino, Hiromasa Sawamura, Koji Takahashi, Hiroya Hara, Yosuke Kudo, Kenzo Yamanaka, Tomoko Kaida, Kazunori Miyata, Makoto Aihara, Ken Johkura","doi":"10.1007/s10384-024-01132-9","DOIUrl":"10.1007/s10384-024-01132-9","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the effects of modifying head position and of static ocular counter-rolling (OCR) on abduction and adduction in saccadic eye movements using a head-mounted video-oculographic device.</p><p><strong>Study design: </strong>A clinical observational study.</p><p><strong>Methods: </strong>The peak velocities and amplitude gains of visually guided 12° saccades were binocularly measured in 21 healthy volunteers with their heads in the upright vertical (0°) and horizontal (± 90°, bilateral side-lying) postures, and in 6 participants with their head positions bilaterally tilted by 30°. The rotation angles of eyeballs generated via OCR in the bilateral 30° and 90° head positions were evaluated in five participants.</p><p><strong>Results: </strong>Peak velocities and gains were significantly higher with the head in the 0° position compared to ± 90°. The decreases in peak velocities and gains at ± 90° were not affected by the apogeotropic or geotropic directions. Faster peak velocities and greater gains on abduction, rather than adduction, were observed under each test condition. The tendencies toward faster peak velocity and greater gain in the 0° head position rather than bilaterally tilted at 30° were preserved. The absolute rotation angles at ± 90° were larger than those at 30°.</p><p><strong>Conclusions: </strong>Head position affected the peak velocities and gains of both abduction and adduction saccades. The findings suggest that modified force vectors exerted by different eye muscles recruited during OCR play a role. Our research provides valuable insights for assessing eye movements across various head positions.</p>","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":"144-151"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11821700/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142921688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improvements in visual function early after cataract surgery in eyes implanted with multifocal intraocular lenses.","authors":"Ken Hayashi, Motoaki Yoshida, Shin-Ichi Manabe, Akira Hirata","doi":"10.1007/s10384-024-01130-x","DOIUrl":"10.1007/s10384-024-01130-x","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the improvements in all-distance visual acuity (VA) and contrast sensitivity early after cataract surgery among eyes implanted with multifocal and monofocal intraocular lenses (IOLs).</p><p><strong>Study design: </strong>Nonrandomized comparative study.</p><p><strong>Methods: </strong>Forty-two eyes with a trifocal IOL (Alcon, PanOptix^®), 42 eyes with a combined bifocal and extended-depth-of-focus (EDF) IOL (Johnson & Johnson, Synergy^®), and 84 eyes with a monofocal IOL were recruited. Uncorrected or corrected VA at various distances, and photopia and mesopic contrast VA were examined at 1 day and 3 months postoperatively. Improvements in these VAs were compared between time points and among groups.</p><p><strong>Results: </strong>Mean uncorrected as well as corrected VA improved significantly between 1 day and 3 months postoperatively at almost all distances in the trifocal and combined bifocal + EDF groups (P ≤ 0.018), and at the intermediate distance of 1.0 m and far distances in the monofocal group (P ≤ 0.031). Mean improvements in near uncorrected VA at 0.3 m, intermediate VA at 0.5 m, and far VA at 2.0, 3.0, and 5.0 m were significantly greater in the multifocal groups than in the monofocal group (P ≤ 0.032). Improvements in photopic and mesopic contrast VA at most contrasts were significantly better in the multifocal groups (P ≤ 0.021).</p><p><strong>Conclusion: </strong>Mean uncorrected or corrected VA at almost all distances and contrast sensitivity at most contrasts improved significantly early after surgery in eyes implanted with multifocal IOLs, and the improvements in VA at most distances and in contrast sensitivity were better with multifocal IOLs than with monofocal IOLs.</p>","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":"32-42"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-year results of trabeculectomy with emphasis on the effect of patients' age.","authors":"Yuto Iwaki, Sotaro Mori, Mina Okuda-Arai, Fumio Takano, Kaori Ueda, Mari Sakamoto, Yuko Yamada-Nakanishi, Makoto Nakamura","doi":"10.1007/s10384-024-01131-w","DOIUrl":"10.1007/s10384-024-01131-w","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated the association between one-year surgical outcomes following trabeculectomy and age, accounting for confounding factors.</p><p><strong>Study design: </strong>Retrospective observational study.</p><p><strong>Method: </strong>Analyzing data from 305 patients undergoing initial trabeculectomy from 2019 onward, we employed three approaches to adjust variables: stratified analysis, regression analysis, and propensity score matching. Surgical success at 1-year post-surgery was defined by two criteria: achieving intraocular pressure of between 5 and 15 mmHg with a ≥ 20% reduction compared to pre-surgery levels and no additional glaucoma surgery (Criterion A); achieving intraocular pressure of between 5 and 12 mmHg with a ≥ 30% reduction compared to pre-surgery levels and no additional glaucoma surgery (Criterion B).</p><p><strong>Results: </strong>Stratified analysis by age unveiled a significant increase in exfoliation glaucoma (XFG) and a trend towards shorter axial lengths with advancing age (both p < 0.0001). Older age groups were more likely to experience surgical failure in both Criterion A and B (p = 0.21, < 0.01). Univariate analysis showed age as a significant factor in surgical failure for Criterion A (p < 0.05) and a nearly significant factor for Criterion B (p = 0.12). However, this trend was not evident in multivariate analysis (p = 0.23/0.88), where XFG became a significant factor for surgical failure (both p < 0.001) in Criteria A and B. Propensity score matching revealed no significant differences in surgical success rates for Criteria A and B between younger and older patients (p = 1.00 and 0.88).</p><p><strong>Conclusion: </strong>Age is not a primary determinant of failure in trabeculectomy; however, the increasing incidence of XFG with aging suggests a potential for poorer outcomes.</p>","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":"93-100"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11821737/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparisons of oscillatory potentials and 30 Hz flicker electroretinograms for discriminating eyes with diabetic retinopathy from normal eyes.","authors":"Mana Gonmori, Shigeki Machida, Shinya Inoue, Satoshi Ebihara, Keita Misu","doi":"10.1007/s10384-024-01154-3","DOIUrl":"10.1007/s10384-024-01154-3","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the amplitudes and implicit times of the oscillatory (OPs) of the full-field electroretinograms (ERGs) to those of the 30 Hz flicker ERGs in differentiating eyes with diabetic retinopathy (DR) from normal eyes.</p><p><strong>Study design: </strong>Single-center observational study.</p><p><strong>Methods: </strong>Full-field ERGs were recorded in 55 patients with Type 2 diabetes mellitus (DM) and 20 normal control subjects. The amplitudes and implicit times of the OPs and of the 30 Hz flicker ERGs were measured. Optical coherence tomography angiography (OCTA) was used to record 3×3 mm enface images of the retina from which the vascular density (VD) of the superficial capillary plexus (SCP) and deep capillary plexus (DCP) were obtained. The receiver operating characteristic (ROC) curves were used to determine the ability of each ERG parameter to discriminate diseased eyes from normal eyes. The significance of the correlations between each ERG parameter and the VD of the SCP and DCP was determined.</p><p><strong>Results: </strong>The area under the ROC curves (AUCs) was significantly larger for the implicit times than for the amplitudes of each ERG component (P<0.005). There were no significant differences in the AUCs between the OPs and 30 Hz flicker ERGs in differentiating eyes with DM or DR from normal eyes. The implicit time of the 30 Hz flicker ERG had the highest significant correlation coefficient with the VD of the DCP (r = - 0.31, P <0.001).</p><p><strong>Conclusions: </strong>The OPs and 30 Hz flicker ERGs have equal ability in differentiating eyes with DR from normal eyes but with better ability for the implicit times than the amplitudes. The implicit time of the 30 Hz flicker ERG is the most sensitive parameter that is correlated with the reduction of VD among the full-field ERG components.</p>","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":"49-58"},"PeriodicalIF":2.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}