Japanese Journal of Ophthalmology最新文献

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Modulation of the peak velocities and gains of abduction and adduction saccades according to head position.
IF 2.1 3区 医学
Japanese Journal of Ophthalmology Pub Date : 2025-01-03 DOI: 10.1007/s10384-024-01132-9
Hana Mino, Hiromasa Sawamura, Koji Takahashi, Hiroya Hara, Yosuke Kudo, Kenzo Yamanaka, Tomoko Kaida, Kazunori Miyata, Makoto Aihara, Ken Johkura
{"title":"Modulation of the peak velocities and gains of abduction and adduction saccades according to head position.","authors":"Hana Mino, Hiromasa Sawamura, Koji Takahashi, Hiroya Hara, Yosuke Kudo, Kenzo Yamanaka, Tomoko Kaida, Kazunori Miyata, Makoto Aihara, Ken Johkura","doi":"10.1007/s10384-024-01132-9","DOIUrl":"https://doi.org/10.1007/s10384-024-01132-9","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the effects of modifying head position and of static ocular counter-rolling (OCR) on abduction and adduction in saccadic eye movements using a head-mounted video-oculographic device.</p><p><strong>Study design: </strong>A clinical observational study.</p><p><strong>Methods: </strong>The peak velocities and amplitude gains of visually guided 12° saccades were binocularly measured in 21 healthy volunteers with their heads in the upright vertical (0°) and horizontal (± 90°, bilateral side-lying) postures, and in 6 participants with their head positions bilaterally tilted by 30°. The rotation angles of eyeballs generated via OCR in the bilateral 30° and 90° head positions were evaluated in five participants.</p><p><strong>Results: </strong>Peak velocities and gains were significantly higher with the head in the 0° position compared to ± 90°. The decreases in peak velocities and gains at ± 90° were not affected by the apogeotropic or geotropic directions. Faster peak velocities and greater gains on abduction, rather than adduction, were observed under each test condition. The tendencies toward faster peak velocity and greater gain in the 0° head position rather than bilaterally tilted at 30° were preserved. The absolute rotation angles at ± 90° were larger than those at 30°.</p><p><strong>Conclusions: </strong>Head position affected the peak velocities and gains of both abduction and adduction saccades. The findings suggest that modified force vectors exerted by different eye muscles recruited during OCR play a role. Our research provides valuable insights for assessing eye movements across various head positions.</p>","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142921688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidence of corneal perforation and lagophthalmos in patients with leprosy in Japan based on 40-year observations.
IF 2.1 3区 医学
Japanese Journal of Ophthalmology Pub Date : 2025-01-03 DOI: 10.1007/s10384-024-01156-1
Takashi Ono, Takuya Iwasaki, Keita Takada, Shota Tokuda, Toshihiro Sakisaka, Yosai Mori, Ryohei Nejima, Masao Kakibuchi, Takashi Miyai, Kazunori Miyata
{"title":"Incidence of corneal perforation and lagophthalmos in patients with leprosy in Japan based on 40-year observations.","authors":"Takashi Ono, Takuya Iwasaki, Keita Takada, Shota Tokuda, Toshihiro Sakisaka, Yosai Mori, Ryohei Nejima, Masao Kakibuchi, Takashi Miyai, Kazunori Miyata","doi":"10.1007/s10384-024-01156-1","DOIUrl":"https://doi.org/10.1007/s10384-024-01156-1","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to report the incidence, characteristics, and prognosis of corneal perforation in patients with leprosy.</p><p><strong>Study design: </strong>Retrospective observational study.</p><p><strong>Methods: </strong>Patients who presented with leprosy and visited a specialised ophthalmology hospital (Miyata Eye Hospital, Miyazaki, Japan) between 1980 and 2020 were included. Their medical charts were retrospectively reviewed, and the incidence of lagophthalmos and corneal perforation was examined. Additionally, the presentation, treatment, and prognosis of patients with corneal perforations were assessed.</p><p><strong>Results: </strong>In total, the records of 472 eyes of 236 patients (128 men and 108 women; mean age, 81.2 ± 7.5 years) diagnosed with leprosy were reviewed. Forty-one patients were diagnosed with lagophthalmos, and two of these patients (4.8%) showed signs of corneal perforation. Patients with lagophthalmos presented significantly more frequently with cicatricial contraction of eyelids (p < 0.001), superficial punctate keratopathy (p < 0.001), epithelial defect (p = 0.039), and corneal ulcer (p < 0.001) compared with patients without lagophthalmos. Patients with corneal perforation had uveitis more frequently compared with those without corneal perforation (p = 0.01).</p><p><strong>Conclusion: </strong>Patients with leprosy frequently develop lagophthalmos. Patients with uveitis associated with leprosy are especially at risk of corneal perforation.</p>","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142921679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2021 trends in the treatment of patients with strabismus in Japan. 日本治疗斜视患者的 2021 年趋势。
IF 2.1 3区 医学
Japanese Journal of Ophthalmology Pub Date : 2024-12-16 DOI: 10.1007/s10384-024-01144-5
Keiko Kunimi, Toshiaki Goseki, Sachiko Nishina, Takashi Negishi, Miho Sato
{"title":"2021 trends in the treatment of patients with strabismus in Japan.","authors":"Keiko Kunimi, Toshiaki Goseki, Sachiko Nishina, Takashi Negishi, Miho Sato","doi":"10.1007/s10384-024-01144-5","DOIUrl":"https://doi.org/10.1007/s10384-024-01144-5","url":null,"abstract":"<p><strong>Purpose: </strong>To clarify the actual status of strabismus surgery and botulinum toxin (BTX) therapy in Japan in the year 2021.</p><p><strong>Study design: </strong>Cross-sectional study.</p><p><strong>Methods: </strong>We conducted a national survey of strabismus treatment in 2021 using a questionnaire consistent with a previous 2013 survey, incorporating additional questions about BTX therapy.</p><p><strong>Results: </strong>Among the 378 responding institutions, strabismus surgery or BTX therapy, or both, was performed at 185 institutions (49%; total cases, 10,767). In 151 (40%), 32 (8%), and 2 (1%) institutions, surgery only, surgery and BTX therapy, and BTX therapy only were performed, respectively. The distribution of institutions where strabismus surgery was performed consisted of 4 prefectures, accounting for 48% of the total, whereas no strabismus surgery was performed at any institution in 3 prefectures. Although the highest percentage of patients (23%) was aged between 10 and 19 years, 48.2% of the patients were aged 20 years or older, and 17% of them were aged 60 years or older. Exotropia (XT) was the most common type of strabismus (55%) followed by esotropia (ET) (24%). In terms of complex surgeries, 80.2% (more than 100 cases) were performed at institutions with more than 100 cases. Of the 34 institutions where BTX therapy was performed, 52% were performed at a single institution, and 18% were performed at 2 institutions where no strabismus surgery was performed. Patients with scarring in the extraocular muscles, such as thyroid eye disease, were the most treated, followed by those with ET, who were mainly given injection treatment.</p><p><strong>Conclusion: </strong>Institutions where strabismus surgery and BTX therapy could be performed were concentrated and limited.</p>","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Three-year outcomes of surgical bleb revision with mitomycin C for early scarring bleb after trabeculectomy. 使用丝裂霉素 C 对小梁切除术后的早期瘢痕眼泡进行手术修补的三年疗效。
IF 2.1 3区 医学
Japanese Journal of Ophthalmology Pub Date : 2024-11-21 DOI: 10.1007/s10384-024-01142-7
Risa Caraher-Masuda, Mari Sakamoto, Mina Okuda, Fumio Takano, Sotaro Mori, Kaori Ueda, Akiyasu Kanamori, Yuko Yamada-Nakanishi, Makoto Nakamura
{"title":"Three-year outcomes of surgical bleb revision with mitomycin C for early scarring bleb after trabeculectomy.","authors":"Risa Caraher-Masuda, Mari Sakamoto, Mina Okuda, Fumio Takano, Sotaro Mori, Kaori Ueda, Akiyasu Kanamori, Yuko Yamada-Nakanishi, Makoto Nakamura","doi":"10.1007/s10384-024-01142-7","DOIUrl":"https://doi.org/10.1007/s10384-024-01142-7","url":null,"abstract":"<p><strong>Purpose: </strong>To report the 3-year outcomes of surgical bleb revision (SBR) with mitomycin C (MMC) for early scarring bleb after trabeculectomy (TLE).</p><p><strong>Study design: </strong>Retrospective observational study.</p><p><strong>Methods: </strong>We included glaucoma patients aged ≧ 18 who underwent SBR with MMC within 6 months of their first TLE at Kobe University Hospital and were followed for at least 6 months. The primary outcome measure was the three-year success rate of SBR. We defined surgical success as: intraocular pressure (IOP) reduction ≧ 20% from baseline and 5 ≦ IOP ≦ 18 mmHg. Failure was defined when the IOP deviated from the criteria, when the eye required additional glaucoma surgery, and when the eye lost light perception. Complete success (CS) was success without glaucoma medications and qualified success (QS) was success with glaucoma medications. The secondary outcome measures included IOP, the number of glaucoma medications, mean deviation (MD), best corrected visual acuity (BCVA), corneal endothelial cell density (ECD), and surgical complications.</p><p><strong>Results: </strong>Sixty-eight eyes of 68 patients were analyzed. The median interval between initial TLE and SBR was 2 months. Overall success rate at three-year after SBR were 45.1% and 9.6% for QS and CS, respectively. A greater number of medications used before TLE was a contributing factor to failure (P = 0.02). 22 eyes (32.4%) underwent additional glaucoma surgery, and 41 eyes (60.3%) were spared from additional glaucoma surgery within 3 years after SBR. The median IOP decreased form 24.0 mmHg to 11.0 mmHg 3 years after SBR, and the number of medications decreased from 4 to 2 (P < 0.01). MD remained unchanged, but BCVA and ECD decreased at 3years postoperatively. There were no serious complications of SBR.</p><p><strong>Conclusion: </strong>SBR may be an effective treatment option for early scarring blebs after TLE but is unsuccessful in eyes that have used many glaucoma medications prior to TLE.</p>","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142681813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Scientific Reviewers. 科学评审员。
IF 2.1 3区 医学
Japanese Journal of Ophthalmology Pub Date : 2024-11-21 DOI: 10.1007/s10384-024-01136-5
{"title":"Scientific Reviewers.","authors":"","doi":"10.1007/s10384-024-01136-5","DOIUrl":"https://doi.org/10.1007/s10384-024-01136-5","url":null,"abstract":"","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142681811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical and pathologic characteristics of inflamed juvenile conjunctival nevus and its treatment with immunosuppressant eye drops. 炎性幼年结膜痣的临床和病理特征以及用免疫抑制剂滴眼液对其进行的治疗。
IF 2.1 3区 医学
Japanese Journal of Ophthalmology Pub Date : 2024-11-16 DOI: 10.1007/s10384-024-01140-9
Ayako Tomoda, Kaoru Araki-Sasaki, Hiroto Obata, Shinji Ideta, Masahiko Kuroda, Koji Fujita, Yasuhiro Osakabe, Kanji Takahashi
{"title":"Clinical and pathologic characteristics of inflamed juvenile conjunctival nevus and its treatment with immunosuppressant eye drops.","authors":"Ayako Tomoda, Kaoru Araki-Sasaki, Hiroto Obata, Shinji Ideta, Masahiko Kuroda, Koji Fujita, Yasuhiro Osakabe, Kanji Takahashi","doi":"10.1007/s10384-024-01140-9","DOIUrl":"https://doi.org/10.1007/s10384-024-01140-9","url":null,"abstract":"<p><strong>Purpose: </strong>To clarify the clinical and pathologic findings of 7 patients with inflamed juvenile conjunctival nevus (IJCN) treated with tacrolimus.</p><p><strong>Study design: </strong>Retrospective study.</p><p><strong>Subjects and methods: </strong>The medical records of 7 male patients diagnosed with IJCN between February 2007 and October 2022 at the Kansai Medical University Hospital and Ideta Eye Hospital were retrospectively reviewed. The patients' mean age was 11.3 (8-20) years, and the average follow-up period was 18 months. The patients underwent anterior segment optical coherence tomography (AS-OCT) and anterior segment optical coherence tomography angiography (AS-OCTA). All the patients were treated with steroids or immunosuppressant eye drops, or both. Histopathologic examinations were performed on specimens resected from 2 patients.</p><p><strong>Results: </strong>The clinical characteristics of IJCN were as follows: (1) presence of cysts within a pigmented conjunctival mass, (2) tumor accompanied by feeder vessels, and (3) predominantly found in boys with allergic diseases. AS-OCT and AS-OCTA revealed the presence of a cystic structure with poor vascular signals within it and numerous vessels distributed on the sclera underlying the lesion. Immunosuppressant eye drops relieved the congestion, diminished the inflow vessels, and induced shrinkage of the cysts in all the patients. Histopathologic examinations revealed infiltration of inflammatory cells such as lymphocytes and macrophages and low proliferative activity of melanocytes with no division pattern.</p><p><strong>Conclusions: </strong>This study clarified the clinical and histologic characteristics of IJCN. Noninvasive AS-OCT and AS-OCTA might be useful for diagnosing IJCN. The histopathologic findings of this study indicate that immunosuppressive and antiallergic agents can effectively bring about disease remission.</p>","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidence of microbial keratitis associated with overnight orthokeratology: a multicenter collaborative study. 与隔夜角膜矫形术相关的微生物性角膜炎发病率:一项多中心合作研究。
IF 2.1 3区 医学
Japanese Journal of Ophthalmology Pub Date : 2024-11-16 DOI: 10.1007/s10384-024-01137-4
Takahiro Hiraoka, Saiko Matsumura, Yuichi Hori, Kazutaka Kamiya, Kazunori Miyata, Tetsuro Oshika
{"title":"Incidence of microbial keratitis associated with overnight orthokeratology: a multicenter collaborative study.","authors":"Takahiro Hiraoka, Saiko Matsumura, Yuichi Hori, Kazutaka Kamiya, Kazunori Miyata, Tetsuro Oshika","doi":"10.1007/s10384-024-01137-4","DOIUrl":"https://doi.org/10.1007/s10384-024-01137-4","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the incidence of microbial keratitis among Japanese patients wearing orthokeratology (ortho-k) lenses STUDY DESIGN: Retrospective multicenter study METHOD: This study was conducted at 4 hospitals in Japan and involved 1438 patients who had been prescribed ortho-k lenses and had worn them for at least 3 months. Data on patient demographics, lens characteristics, lens care systems, and presence of microbial keratitis were extracted from the medical records. Duration of ortho-k lens wear was calculated from the original fitting date to the patient's last visit, with the total years of lens wear used as person-years of lens wear. The incidence of microbial keratitis was calculated by dividing the number of infected cases by the total person-years of lens wear for all enrolled participants.</p><p><strong>Results: </strong>Among the 1438 patients, 753 were male and 685 were female, with a mean age of 12.7 ± 5.4 years. The mean duration of ortho-k lens wear was 5.2 ± 4.5 years, and the mean lens power was -3.52 ± 1.41 D. The total person-years of lens wear for all enrolled patients was 7415. Four cases of microbial keratitis were identified, resulting in an overall incidence of microbial keratitis of 5.4 (95% CI: 1.0-9.8) per 10,000 patient-years among ortho-k lens wearers.</p><p><strong>Conclusion: </strong>This study represents the largest sample size to date for estimating the incidence of microbial keratitis associated with ortho-k lenses. The incidence was similar to or slightly lower than that of previous studies on ortho-k-related microbial keratitis and also comparable to that of daily wear soft contact lenses.</p>","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of trabeculectomy on the postoperative central visual field as revealed by refraction values. 小梁切除术对术后中心视野的影响,从屈光度值可以看出。
IF 2.1 3区 医学
Japanese Journal of Ophthalmology Pub Date : 2024-11-08 DOI: 10.1007/s10384-024-01139-2
Kosuke Nakajima, Rei Sakata, Shiroaki Shirato, Makoto Aihara
{"title":"Effects of trabeculectomy on the postoperative central visual field as revealed by refraction values.","authors":"Kosuke Nakajima, Rei Sakata, Shiroaki Shirato, Makoto Aihara","doi":"10.1007/s10384-024-01139-2","DOIUrl":"https://doi.org/10.1007/s10384-024-01139-2","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effects of trabeculectomy on the rate of deterioration of the central visual field (VF) in patients with normal-tension glaucoma (NTG), as revealed by refraction values.</p><p><strong>Study design: </strong>Retrospective case series.</p><p><strong>Methods: </strong>We retrospectively analyzed 28 eyes, including 12 high myopic (spherical equivalent [SE] < - 6 diopters without pathological myopia) and 16 non-high myopic (SE ≥ - 6 diopters) eyes. The rate of VF deterioration (dB/year) was determined using linear regression analysis of 30 -2 and 10 -2 VF tests. The Wilcoxon signed-rank test was used to compare deterioration rates between groups. To assess the influence of initial post-surgery effects, statistical analyses were conducted with and without data from the initial postoperative VF exam.</p><p><strong>Results: </strong>Trabeculectomy significantly reduced intraocular pressure (IOP) in myopic (14.1 to 9.0 mmHg, P ≤ 0.01) and non-myopic (13.4 to 9.5 mmHg, P ≤ 0.01) eyes. Postoperatively, the 10-2 VF deterioration rate significantly decreased in myopic (- 1.31 to - 0.55 dB/year, P = 0.01) and non-myopic (- 0.80 to - 0.30 dB/year, P = 0.03) eyes. Excluding the first postoperative VF exam, the deterioration rates were - 0.51 ± 0.24 dB/year and - 0.54 ± 0.89 dB/year, respectively, indicating a minor impact on progression assessment.</p><p><strong>Conclusions: </strong>Trabeculectomy may mitigate central VF deterioration in myopic NTG patients, emphasizing the potential benefits of timely surgical intervention. Further studies are needed to determine the optimal timing for surgery.</p>","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of choroidal detachment with and without hypotony after Ahmed valve implantation. 艾哈迈德瓣膜植入术后脉络膜脱落伴下垂与不伴有下垂的比较。
IF 2.1 3区 医学
Japanese Journal of Ophthalmology Pub Date : 2024-11-08 DOI: 10.1007/s10384-024-01138-3
Sang Wook Jin, Jung Woo Heo, Hee Bae Ahn
{"title":"Comparison of choroidal detachment with and without hypotony after Ahmed valve implantation.","authors":"Sang Wook Jin, Jung Woo Heo, Hee Bae Ahn","doi":"10.1007/s10384-024-01138-3","DOIUrl":"https://doi.org/10.1007/s10384-024-01138-3","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the clinical manifestations of and risk factors for choroidal detachment (CD) with or without hypotony after Ahmed valve implantation (AVI).</p><p><strong>Study design: </strong>Retrospective, consecutive case series.</p><p><strong>Methods: </strong>We enrolled patients with glaucoma who underwent AVI, and divided them into CD and non-CD groups. The patients with CD were divided into those with and without hypotony. Data collected from the chart review before and after AVI included patient demographics and ocular characteristics. We analyzed the risk factors for CD development. The relationship between hypotony and CD development was also analyzed.</p><p><strong>Results: </strong>Among the 387 eyes, 63 developed CD. Among these 63 eyes, 42 had CD with hypotony and 21 had CD without hypotony. Multivariate regression analysis revealed that age (P < 0.001), lens status (P < 0.001), history of diabetes mellitus (DM) (P = 0.011), and history of hypertension (HTN) (P = 0.002) were significant predictors of CD development. Neovascular glaucoma (NVG) showed 42.9% of CD cases without hypotony. This rate was higher than primary open angle glaucoma (POAG) and exfoliative glaucoma (XFG). The rate of anterior chamber formation as treatment of CD was significantly higher in CD with hypotony than in CD without hypotony.</p><p><strong>Conclusions: </strong>Older age, pseudophakic eyes, DM, and HTN are significantly associated with CD development after AVI. NVG has higher incidence rates of CD without hypotony compared with POAG and XFG. Therefore, clinicians should pay attention to CD development after AVI especially in NVG, even if a patient is not in a hypotonic state.</p>","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142604444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes, efficacy and risk factors of 27-Gauge vitrectomy for diabetic tractional retinal detachment in Japanese patients. 27号玻璃体切割术治疗日本糖尿病牵引性视网膜脱离的结果、疗效和风险因素。
IF 2.1 3区 医学
Japanese Journal of Ophthalmology Pub Date : 2024-11-06 DOI: 10.1007/s10384-024-01135-6
Risa Nishigushi, Ayumi Usui-Ouchi, Yoshihito Sakanishi, Kazunori Tamaki, Keitaro Mashimo, Rei Ito, Toshiro Sakuma, Nobuyuki Ebihara, Shintaro Nakao
{"title":"Outcomes, efficacy and risk factors of 27-Gauge vitrectomy for diabetic tractional retinal detachment in Japanese patients.","authors":"Risa Nishigushi, Ayumi Usui-Ouchi, Yoshihito Sakanishi, Kazunori Tamaki, Keitaro Mashimo, Rei Ito, Toshiro Sakuma, Nobuyuki Ebihara, Shintaro Nakao","doi":"10.1007/s10384-024-01135-6","DOIUrl":"https://doi.org/10.1007/s10384-024-01135-6","url":null,"abstract":"<p><strong>Purpose: </strong>Diabetic retinopathy leads to vision-threatening complications, such as proliferative diabetic retinopathy and tractional retinal detachment (TRD) and is a major global health concern. Despite advancements in vitrectomy techniques, challenges exist in managing postoperative complications and long-term visual acuity. This study aimed to evaluate postoperative outcomes of 27-gauge pars plana vitrectomy (27 g PPV) for diabetic TRD and identify associated risk factors.</p><p><strong>Study design: </strong>Retrospective study.</p><p><strong>Methods: </strong>This study included 94 eyes of 74 patients who underwent 27 g PPV for diabetic TRD between July 2017 and September 2022 at Juntendo University Urayasu Hospital, Japan. Patient demographics, preoperative characteristics, intraoperative details, and postoperative outcomes were examined. Statistical analyses were performed to identify factors influencing postoperative visual acuity.</p><p><strong>Results: </strong>Mean follow-up duration was 23.1 ± 14.6 months. Postoperatively, visual acuity (LogMAR) improved significantly from 1.34 ± 0.82 to 0.65 ± 0.79 (P < 0.0001). Postoperative complications included persistent vitreous hemorrhage (15%) and neovascular glaucoma (4%). Final retinal reattachment rate was 97%. Preoperatively, macular detachment (P < 0.0001) and Grade IV TRD (P < 0.0001) severity were significantly associated with poor final best corrected visual acuity (P < 0.0001). Preoperative macular detachment (P < 0.0001), Grade IV TRD (P < 0.0001), intraoperative iatrogenic breaks (P = 0.031), and postoperative neovascular glaucoma (P < 0.0001) were identified as significant predictors of poor postoperative visual outcomes through multivariate analysis.</p><p><strong>Conclusion: </strong>This study highlights the efficacy of 27 g PPV in improving visual acuity in patients with diabetic TRD. Despite favorable outcomes, attention to preoperative risk factors and meticulous surgical techniques remain crucial for optimizing long-term visual prognosis in these patients.</p>","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142582795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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