Japanese Journal of Ophthalmology最新文献_第2页

Assessment of the transscleral removal technique for subretinal proliferative tissues during vitrectomy for rhegmatogenous retinal detachment.

IF 2.1 3区医学

Japanese Journal of Ophthalmology Pub Date : 2025-01-23 DOI: 10.1007/s10384-024-01143-6

Tomoyuki Ishibashi, Ryo Inoue, Hiroshi Nakashima, Kazuyuki Emi

{"title":"Assessment of the transscleral removal technique for subretinal proliferative tissues during vitrectomy for rhegmatogenous retinal detachment.","authors":"Tomoyuki Ishibashi, Ryo Inoue, Hiroshi Nakashima, Kazuyuki Emi","doi":"10.1007/s10384-024-01143-6","DOIUrl":"https://doi.org/10.1007/s10384-024-01143-6","url":null,"abstract":"Purpose: To provide insights into the transscleral removal technique for subretinal proliferative tissues (SRP).Study design: Retrospective, single-center case series.Methods: Patients who underwent transscleral removal of SRP during vitrectomy for rhegmatogenous retinal detachment (RRD) were included. The preoperative RRD extent, SRP distribution, intraoperative maneuvers, complications, and surgical outcomes were assessed.Results: Seven eyes of seven patients were enrolled for surgery. The RRD extent involved four quadrants in two eyes, three quadrants in three eyes, and two quadrants in the remaining two eyes. SRP were widely distributed beneath the detached retina in all the cases, with submacular SRP present in six cases. In these six cases, all the SRP, including the submacular SRP, could be removed without creating retinotomies via 1 or 2 subretinal trocars. However, peripheral SRP with extensive and strong adhesion to the retina required multiple retinotomies and conventional bimanual removal in one case. Surgical failure, attributable to the transscleral technique, occurred in one case due to a missed retinal puncture that occurred during subretinal trocar insertion, resulting in recurrent RRD. This patient had RRD within two quadrants, and the subretinal space could not be adequately dilated before insertion. All the patients had achieved retinal reattachment without deterioration of visual acuity at the final follow-up visit.Conclusion: The transscleral removal technique was suitable for the removal of SRP, including the posterior pole area, with minimal retinal damage. However, this technique may not be appropriate for SRP removal with extensive and strong adhesions or for cases with relatively nonextensive RRD.","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of ethylenediaminetetraacetic acid chelation for calcific band keratopathy on corneal topography assessed by fourier harmonic analysis.

IF 2.1 3区医学

Japanese Journal of Ophthalmology Pub Date : 2025-01-23 DOI: 10.1007/s10384-025-01160-z

Shoko Saito, Yumi Kusumi, Yoji Takano, Masaki Fukui, Masakazu Yamada

{"title":"Effects of ethylenediaminetetraacetic acid chelation for calcific band keratopathy on corneal topography assessed by fourier harmonic analysis.","authors":"Shoko Saito, Yumi Kusumi, Yoji Takano, Masaki Fukui, Masakazu Yamada","doi":"10.1007/s10384-025-01160-z","DOIUrl":"https://doi.org/10.1007/s10384-025-01160-z","url":null,"abstract":"Purpose: Chemical chelation with ethylenediaminetetraacetic acid (EDTA) is an established treatment for calcific band keratopathy (CBK), whereas removal of calcium deposits from the subepithelial layer of the cornea may cause corneal irregularity. Using Fourier harmonic analysis, we analyzed the corneal topography in eyes with CBK treated by EDTA chelation.Study design: Retrospective, single-center study.Methods: This study included 42 eyes of 26 patients who underwent chemical chelation using EDTA for CBK at the Kyorin University Hospital. Clinical data included age, sex, refraction, visual acuity, operation records, and corneal topography. Corneal topography was evaluated by a TMS-5 Corneal Topographer, and 3.0- and 6.0-mm-diameter Fourier series harmonic analyses were performed. Refraction, visual acuity, and parameters of corneal topography were compared before surgery and at 1 and 4 weeks postoperatively.Results: Visual acuity and refraction (spherical equivalent and astigmatism) did not significantly change at 4 weeks postoperatively. Fourier harmonic analysis revealed that there were no time serial changes in the spherical component and regular astigmatism in both 3.0- and 6.0-mm analyses. Asymmetry astigmatism, and high-order irregularity significantly increased at 1 week postoperatively but decreased at 4 weeks postoperatively, with no statistical differences compared with preoperative data.Conclusion: The effects of EDTA treatment on the corneal shape and refraction are minimal, which is beneficial for maintaining visual function in patients with CBK.","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative analysis of axial length measurement method for eyes with submacular hemorrhage. 黄斑下出血眼轴长测量方法的比较分析。

IF 2.1 3区医学

Japanese Journal of Ophthalmology Pub Date : 2025-01-20 DOI: 10.1007/s10384-024-01147-2

Masakazu Nagayama, Shuhei Kimura, Mio Morizane Hosokawa, Yusuke Shiode, Ryo Matoba, Tetsuro Morita, Keisuke Kanenaga, Yuki Morizane

{"title":"Comparative analysis of axial length measurement method for eyes with submacular hemorrhage.","authors":"Masakazu Nagayama, Shuhei Kimura, Mio Morizane Hosokawa, Yusuke Shiode, Ryo Matoba, Tetsuro Morita, Keisuke Kanenaga, Yuki Morizane","doi":"10.1007/s10384-024-01147-2","DOIUrl":"https://doi.org/10.1007/s10384-024-01147-2","url":null,"abstract":"Purpose: To identify a method for comparing preoperative axial length (AL) measurements with postoperative AL in submacular hemorrhage (SMH).Study design: Retrospective.Methods: This study included 30 patients who underwent vitrectomy for SMH (January 2016-January 2023) with preoperative and postoperative AL data. Preoperative AL was obtained using ultrasonography for the affected eye (aUS-AL) and compared to those measured using optical biometry (OB) for the affected and fellow eyes (aOB-AL and fOB-AL, respectively). Postoperative AL (aPost-AL) was defined as the AL of the affected eye by OB. The absolute differences between the preoperative AL (aUS-AL, aOB-AL, and fOB-AL) and aPost-AL were assessed.Results: aUS-AL, aOB-AL, and fOB-AL values were 23.50 ± 1.41 mm, 23.32 ± 1.40 mm, and 23.66 ± 1.45 mm, respectively, correlating strongly with aPost-AL (23.54 ± 1.37 mm) (all R > 0.95). fOB-AL exceeded aPost-AL significantly (P = 0.02). In all 30 eyes, absolute differences between preoperative AL and aPost-AL were 0.19 ± 0.18 mm, 0.28 ± 0.32 mm, and 0.21 ± 0.22 mm, respectively, which were not significantly different from each other (all P > 0.05). In nine eyes with SMH height > 1000 μm or unmeasurable, the absolute difference between aOB-AL and aPost-AL (0.42 ± 0.33 mm) exceeded that of aUS-AL and aPost-AL (0.10 ± 0.09 mm) (P = 0.003).Conclusion: Although aUS-AL, aOB-AL, and fOB-AL correlated well with postoperative AL in patients with SMH, fOB-AL may be measured longer and aOB-AL shorter in some cases. Therefore, aUS-AL may be considered primarily in determining IOL power of cataract surgery performed in combination with SMH displacement.","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Postoperative outcomes of biopsy versus debulking surgery for immunoglobulin G4-related ophthalmic disease: a retrospective comparative study. 免疫球蛋白g4相关眼病的活检与减体积手术的术后结果：一项回顾性比较研究

IF 2.1 3区医学

Japanese Journal of Ophthalmology Pub Date : 2025-01-20 DOI: 10.1007/s10384-024-01157-0

Rikako Iwasaki, Yoshiyuki Kitaguchi, Takeshi Morimoto, Kohji Nishida

{"title":"Postoperative outcomes of biopsy versus debulking surgery for immunoglobulin G4-related ophthalmic disease: a retrospective comparative study.","authors":"Rikako Iwasaki, Yoshiyuki Kitaguchi, Takeshi Morimoto, Kohji Nishida","doi":"10.1007/s10384-024-01157-0","DOIUrl":"https://doi.org/10.1007/s10384-024-01157-0","url":null,"abstract":"Purpose: To compare the postoperative outcomes of corticosteroid therapy following biopsy with those following debulking surgery in patients with immunoglobulin G4 (IgG4)-related ophthalmic disease (IgG4-ROD).Study design: Retrospective comparative study.Methods: Fifteen patients diagnosed with IgG4-ROD (5 unilateral, 10 bilateral) were retrospectively analyzed. IgG4-ROD was diagnosed based on imaging, histopathology, and blood test results. The biopsy group included patients who underwent resection of minimal tissue for diagnosis, whereas the debulking group included patients who underwent resection of a substantial portion of the mass to decrease the tumor size. Postoperative outcomes after steroid administration, recurrence rates, and changes in lacrimal gland function were compared between the groups.Results: The biopsy and debulking groups included seven and eight patients, respectively. All patients in the biopsy group and 25% of patients in the debulking group required steroid treatment postoperatively (p = 0.0070). Relapse occurred in 71.4% and 12.5% (p = 0.041) and maintenance therapy was required in 57.1% and 12.5% (p = 0.12) patients in the biopsy and debulking groups, respectively. Twelve patients had extraorbital lesions, with one patient receiving corticosteroid treatment for sphenoid bone lesion. Schirmer I test values did not differ preoperatively and postoperatively in either group (biopsy: p = 0.47; debulking: p = 0.72). One patient from the biopsy group developed severe dry eyes, necessitating lacrimal canalicular excision.Conclusions: Debulking surgery effectively reduced the requirement for postoperative steroid administration for recurrent lacrimal gland lesion in patients with IgG4-ROD, indicating its potential as an effective alternative to current standard treatment.","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictive value of enhanced corneal biomechanical parameters for ectasia progression. 增强角膜生物力学参数对扩张进展的预测价值。

IF 2.1 3区医学

Japanese Journal of Ophthalmology Pub Date : 2025-01-20 DOI: 10.1007/s10384-024-01149-0

Shizuka Koh, Renato Ambrósio, Ryota Inoue, Michael W Belin, Naoyuki Maeda, Kohji Nishida

{"title":"Predictive value of enhanced corneal biomechanical parameters for ectasia progression.","authors":"Shizuka Koh, Renato Ambrósio, Ryota Inoue, Michael W Belin, Naoyuki Maeda, Kohji Nishida","doi":"10.1007/s10384-024-01149-0","DOIUrl":"https://doi.org/10.1007/s10384-024-01149-0","url":null,"abstract":"Purpose: To determine whether corneal biomechanical parameters can predict ectasia progression.Study design: Retrospective observational study.Methods: The baseline corneal biomechanical parameters of 64 eyes of 41 young patients (age, < 25 years at the first visit) who were diagnosed with keratoconus (KC) or suspected KC at Osaka University Hospital and followed up for more than two years were reviewed. Suspected KC was defined as borderline cases with no definitive clinical or topographical abnormalities in both eyes. The eyes were divided into progressed (P) and non-progressed (NP) groups using the ABCD grading system of Scheimpflug-based tomography. The Scheimpflug-based corneal biomechanical parameters evaluated included deformation amplitude ratio within 2 mm, integrated radius, Ambrósio relational thickness to the horizontal profile, stiffness parameter at the first applanation, stress-strain index, E-staging, and Corvis Biomechanical Index. The optimized tomographic/biomechanical index (TBIv2), Belin/Ambrósio Enhanced Ectasia Deviation (BAD-D), and inferior-superior axial steepening values from Scheimpflug-based tomography were also evaluated.Results: Twenty-three and 41 eyes were categorized into the P and NP groups, respectively. Logistic regression analysis showed that age, BAD-D, and TBIv2 could predict ectasia progression. The specificity, sensitivity, and area under the receiver operating characteristic curve (AUROC) values for BAD-D combined with age were 0.82, 0.60, and 0.83, respectively, whereas those for TBIv2 combined with age were 0.65, 0.82, and 0.82, respectively.Conclusions: Baseline TBIv2 is a potentially useful predictive marker for ectasia progression in young patients, whereas baseline BAD-D could be used for establishing a definitive diagnosis.","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Short-term efficacy and safety of PreserFlo MicroShunt in Japanese patients with medically treated primary open-angle glaucoma. PreserFlo微分流器在日本经药物治疗的原发性开角型青光眼患者中的短期疗效和安全性。

IF 2.1 3区医学

Japanese Journal of Ophthalmology Pub Date : 2025-01-18 DOI: 10.1007/s10384-024-01159-y

Haruyuki Suzuki, Rei Sakata, Teruki Yamae, Yukako Ishiyama, Koichiro Sugimoto, Hitomi Saito, Megumi Honjo, Shiroaki Shirato, Makoto Aihara

{"title":"Short-term efficacy and safety of PreserFlo MicroShunt in Japanese patients with medically treated primary open-angle glaucoma.","authors":"Haruyuki Suzuki, Rei Sakata, Teruki Yamae, Yukako Ishiyama, Koichiro Sugimoto, Hitomi Saito, Megumi Honjo, Shiroaki Shirato, Makoto Aihara","doi":"10.1007/s10384-024-01159-y","DOIUrl":"https://doi.org/10.1007/s10384-024-01159-y","url":null,"abstract":"Purpose: To assess the efficacy and safety of PreserFlo MicroShunt (PMS) combined with mitomycin C in patients with medically treated primary open-angle glaucoma (POAG).Study design: A retrospective observational study.Methods: The study examined 83 eyes from 83 patients with medically treated glaucoma surgery naive POAG. Preoperative intraocular pressure (IOP) was stratified into three groups: IOP < 15 mmHg (group 1), 15 ≤ IOP < 21 mmHg (group 2), and IOP ≥ 21 mmHg (group 3). IOP levels at week 1, month 1, month 3, and month 6 were evaluated using a linear mixed model, and Kaplan-Meier survival analysis was employed to assess the complete success rate (30% IOP reduction without any medications or interventions) of IOP management. The postoperative complications and interventions were also evaluated.Results: Overall, the mean IOP decreased from 19.2 ± 7.4 mmHg to 11.3 ± 3.1 mmHg, representing a 41% IOP reduction. Especially, in group 1 (mean IOP of 12.8 mmHg), IOP decreased to 10.3 mmHg, achieving a reduction rate of 20%. Overall, 51% (95% confidence interval [CI] 41-62%) of the patients maintained a ≥ 30% IOP reduction (complete success). Minor complications included hypotony (n = 10) and hyphema (n = 30). Needling was performed in 12 eyes, bleb revision in 2, tube re-insertion in 2, and insertion of a second tube in 1.Conclusions: PMS demonstrated significant efficacy in reducing IOP in patients with POAG reagrdless of its preoperative IOP levels. No serious complications affecting the VA were observed.","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Visualization of porcine and human aqueous humor outflow tract anatomies with transparency enhancement. 透明增强的猪和人房水流出道解剖可视化。

IF 2.1 3区医学

Japanese Journal of Ophthalmology Pub Date : 2025-01-18 DOI: 10.1007/s10384-024-01151-6

Yuichi Asahina, Makoto Aihara, Takashi Miyai, Asami Tanaka, Hiroshi Onodera

{"title":"Visualization of porcine and human aqueous humor outflow tract anatomies with transparency enhancement.","authors":"Yuichi Asahina, Makoto Aihara, Takashi Miyai, Asami Tanaka, Hiroshi Onodera","doi":"10.1007/s10384-024-01151-6","DOIUrl":"https://doi.org/10.1007/s10384-024-01151-6","url":null,"abstract":"Purpose: There is no established method for visualizing the three-dimensional (3D) structure of the aqueous humor outflow tract. This study attempted to visualize the 3D structures of porcine and human ocular tissues, particularly the aqueous humor outflow tract using a transparency reagent composed of 2, 2-thiodiethanol.Study design: Clinical and experimental.Methods: The porcine eyes were collected in Japan, and the human eyes were imported from the United States. The human eyes were obtained from a 64-year-old Caucasian woman, arriving 7 days after her death. The specimens were formalin-fixed upon arrival, fluorescently labeled, optically cleared using a transparency-enhancing reagent, and visualized using a confocal microscope.Results: Both porcine and human eyes were visualized to the extent that the choroidal vessels were observed on gross examination. The aqueous humor outflow tract was clearly observed as a luminal structure in the porcine eye, mainly depicted by autofluorescence, and in the human eyes as a luminal structure continuing from the trabecular meshwork without fluorescence.Conclusion: Observations using transparency-enhancing technology enabled us to obtain 3D images useful for visualizing ocular tissues, especially the aqueous humor outflow tract.","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retinal detachment after acute retinal necrosis: a retrospective analysis of hospitalized patients. 急性视网膜坏死后视网膜脱离：住院患者的回顾性分析。

IF 2.1 3区医学

Japanese Journal of Ophthalmology Pub Date : 2025-01-18 DOI: 10.1007/s10384-024-01148-1

Suk Hoon Jung, Sang Un Yi, Young-Hoon Park

{"title":"Retinal detachment after acute retinal necrosis: a retrospective analysis of hospitalized patients.","authors":"Suk Hoon Jung, Sang Un Yi, Young-Hoon Park","doi":"10.1007/s10384-024-01148-1","DOIUrl":"https://doi.org/10.1007/s10384-024-01148-1","url":null,"abstract":"Purpose: To review hospitalized patients with Acute Retinal Necrosis (ARN) and investigate factors associated with subsequent retinal detachment (RD).Study design: Retrospective.Methods: The study included 40 patients (42 eyes), categorized into non-RD (23 eyes) and RD (19 eyes) groups. Patient demographics, ocular findings, treatment history, and visual outcomes were analyzed.Results: The RD group had higher diabetes prevalence and worse initial and final visual acuity (VA) than the non-RD group (p = 0.035, p = 0.001, p = 0.000). The extent of retinal involvement was greater in the RD group (p = 0.000). The total steroid dose up to RD was significantly lower in the RD group (p = 0.023). Worse initial VA (p = 0.035) and greater retinal involvement (p = 0.036) increased the risk of RD. In the RD group, the time from initial symptoms to RD positively correlated with the duration of oral antivirals, the number of intravitreal antiviral injections, and the duration of oral steroids and immunosuppressants (p = 0.000, p = 0.023, p = 0.018, p = 0.001). The use of oral antivirals, steroids, and immunosuppressants was associated with longer median survival times compared to non-use (p = 0.000, p = 0.000, p = 0.048). The group receiving 9-11 intravitreal antiviral injections had a longer median survival time than the 0-4 and 5-8 injection groups (p = 0.009, p = 0.032).Conclusions: In ARN, reduced steroid use due to diabetes may be associated with RD through inflammatory changes. The worse the initial VA and the greater the extent of retinal lesions, the higher the risk of RD. Oral antivirals, intravitreal antiviral injections, oral steroids, and oral immunosuppressants may be effective in delaying RD.","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modulation of the peak velocities and gains of abduction and adduction saccades according to head position. 根据头部位置调节外展和内收扫视的峰值速度和增益。

IF 2.1 3区医学

Japanese Journal of Ophthalmology Pub Date : 2025-01-03 DOI: 10.1007/s10384-024-01132-9

Hana Mino, Hiromasa Sawamura, Koji Takahashi, Hiroya Hara, Yosuke Kudo, Kenzo Yamanaka, Tomoko Kaida, Kazunori Miyata, Makoto Aihara, Ken Johkura

{"title":"Modulation of the peak velocities and gains of abduction and adduction saccades according to head position.","authors":"Hana Mino, Hiromasa Sawamura, Koji Takahashi, Hiroya Hara, Yosuke Kudo, Kenzo Yamanaka, Tomoko Kaida, Kazunori Miyata, Makoto Aihara, Ken Johkura","doi":"10.1007/s10384-024-01132-9","DOIUrl":"https://doi.org/10.1007/s10384-024-01132-9","url":null,"abstract":"Purpose: To assess the effects of modifying head position and of static ocular counter-rolling (OCR) on abduction and adduction in saccadic eye movements using a head-mounted video-oculographic device.Study design: A clinical observational study.Methods: The peak velocities and amplitude gains of visually guided 12° saccades were binocularly measured in 21 healthy volunteers with their heads in the upright vertical (0°) and horizontal (± 90°, bilateral side-lying) postures, and in 6 participants with their head positions bilaterally tilted by 30°. The rotation angles of eyeballs generated via OCR in the bilateral 30° and 90° head positions were evaluated in five participants.Results: Peak velocities and gains were significantly higher with the head in the 0° position compared to ± 90°. The decreases in peak velocities and gains at ± 90° were not affected by the apogeotropic or geotropic directions. Faster peak velocities and greater gains on abduction, rather than adduction, were observed under each test condition. The tendencies toward faster peak velocity and greater gain in the 0° head position rather than bilaterally tilted at 30° were preserved. The absolute rotation angles at ± 90° were larger than those at 30°.Conclusions: Head position affected the peak velocities and gains of both abduction and adduction saccades. The findings suggest that modified force vectors exerted by different eye muscles recruited during OCR play a role. Our research provides valuable insights for assessing eye movements across various head positions.","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142921688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidence of corneal perforation and lagophthalmos in patients with leprosy in Japan based on 40-year observations. 基于40年观察的日本麻风病患者角膜穿孔和眼lagophthalmmos的发生率

IF 2.1 3区医学

Japanese Journal of Ophthalmology Pub Date : 2025-01-03 DOI: 10.1007/s10384-024-01156-1

Takashi Ono, Takuya Iwasaki, Keita Takada, Shota Tokuda, Toshihiro Sakisaka, Yosai Mori, Ryohei Nejima, Masao Kakibuchi, Takashi Miyai, Kazunori Miyata

{"title":"Incidence of corneal perforation and lagophthalmos in patients with leprosy in Japan based on 40-year observations.","authors":"Takashi Ono, Takuya Iwasaki, Keita Takada, Shota Tokuda, Toshihiro Sakisaka, Yosai Mori, Ryohei Nejima, Masao Kakibuchi, Takashi Miyai, Kazunori Miyata","doi":"10.1007/s10384-024-01156-1","DOIUrl":"https://doi.org/10.1007/s10384-024-01156-1","url":null,"abstract":"Purpose: This study aimed to report the incidence, characteristics, and prognosis of corneal perforation in patients with leprosy.Study design: Retrospective observational study.Methods: Patients who presented with leprosy and visited a specialised ophthalmology hospital (Miyata Eye Hospital, Miyazaki, Japan) between 1980 and 2020 were included. Their medical charts were retrospectively reviewed, and the incidence of lagophthalmos and corneal perforation was examined. Additionally, the presentation, treatment, and prognosis of patients with corneal perforations were assessed.Results: In total, the records of 472 eyes of 236 patients (128 men and 108 women; mean age, 81.2 ± 7.5 years) diagnosed with leprosy were reviewed. Forty-one patients were diagnosed with lagophthalmos, and two of these patients (4.8%) showed signs of corneal perforation. Patients with lagophthalmos presented significantly more frequently with cicatricial contraction of eyelids (p < 0.001), superficial punctate keratopathy (p < 0.001), epithelial defect (p = 0.039), and corneal ulcer (p < 0.001) compared with patients without lagophthalmos. Patients with corneal perforation had uveitis more frequently compared with those without corneal perforation (p = 0.01).Conclusion: Patients with leprosy frequently develop lagophthalmos. Patients with uveitis associated with leprosy are especially at risk of corneal perforation.","PeriodicalId":14563,"journal":{"name":"Japanese Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142921679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0