Iranian Journal of Child Neurology最新文献

{"title":"Walking Ability, Participation, and Quality of Life in Children with Spastic Diplegic Cerebral Palsy: A Path Analysis Study.","authors":"Roshank Vameghi,&nbsp;Seyed Ali Hoseini,&nbsp;Samira Heydarian,&nbsp;Hossein Azadeh,&nbsp;Masoud Gharib","doi":"10.22037/ijcn.v17i1.34924","DOIUrl":"https://doi.org/10.22037/ijcn.v17i1.34924","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to design a conceptual model for the effect of various factors on walking ability, participation, and quality of life in children with spastic diplegic cerebral palsy (SDCP) and test it based on field data using path analysis<b>.</b></p><p><strong>Materials & methods: </strong>This cross-sectional study was performed on 181 children with SDCP. The following were used to measure each of the variables: the Modified Ashworth Scale, the Micro Manual Muscle Tester, the Timed Up and Go Test (TUG), the Boyd and Graham test, the goniometer, weight and height, the Gross Motor Function Classification System, the Life Habits Questionnaire, and cerebral palsy Quality of Life Questionnaire for Children. The structural model was tested in Amos 17.</p><p><strong>Results: </strong>All paths of the proposed model were significant (P <0.05). Among evaluated variables, muscle strength (B = -0.466), balance (B = 0.326), and spasticity (B = 0.143) affected walking ability. Moreover, as an intermediate factor, walking ability affected the subjects' participation (B = -0.819) and quality of life (B = -0.183).</p><p><strong>Conclusion: </strong>Muscle strength, balance, and spasticity are the most influential factors in the walking ability of children with SDCP. Furthermore, walking ability and participation are two critical factors in promoting the quality of life of these children.</p>","PeriodicalId":14537,"journal":{"name":"Iranian Journal of Child Neurology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e8/64/ijcn-17-75.PMC10114265.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9551345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel Mutation in the OXCT1 Gene Causing Succinyl-CoA:3-Ketoacid CoA Transferase (SCOT) Deficiency Starting with Neurologic Manifestations.","authors":"Davoud Amirkashani,&nbsp;Mostafa Asadollahi,&nbsp;Rozita Hosseini,&nbsp;Saeed Talebi,&nbsp;Zahra Golchehre,&nbsp;Mohammad Keramatipour","doi":"10.22037/ijcn.v17i2.35963","DOIUrl":"https://doi.org/10.22037/ijcn.v17i2.35963","url":null,"abstract":"<p><p>Succinyl-CoA:3-oxoacid CoA-transferase (SCOT) deficiency is an inborn error of ketone body utilization characterized by intermittent ketoacidosis crises. This study reports the first Iranian patient with SCOT deficiency who presented with seizure and hypotonia at birth. Accordingly, she was consequently re-hospitalized due to hypotonia and respiratory distress. Laboratory tests revealed hyperammonemia, ketonuria, and metabolic acidosis. Besides, the plasma glucose level was normal without any other abnormality. Despite treatment with high-dose bicarbonate, severe acidosis persisted. Poor response to treatment raised a significant diagnostic challenge among specialists until genetic investigation identified a homozygous nonsense mutation (c.79G>T; p.Gly27*) in the OXCT1 gene (NM_000436), causing SCOT deficiency. Genetic studies help clinicians achieve a definite diagnosis of such metabolic disorders. In this case, the accurate and early diagnosis of SCOT deficiency opened new therapeutic possibilities, including frequent carbohydrate-rich meals and low fat and protein diet. Moreover, our findings expand the mutational and clinical spectrum of SCOT deficiency<b>.</b></p>","PeriodicalId":14537,"journal":{"name":"Iranian Journal of Child Neurology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/94/a3/ijcn-17-127.PMC10114279.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9557692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiple supra- and infratentorial cavernous hemangiomas in a five year-old girl.","authors":"Hosein Eslamiyeh,&nbsp;Zahra Eslamiyeh","doi":"10.22037/ijcn.v17i2.37749","DOIUrl":"10.22037/ijcn.v17i2.37749","url":null,"abstract":"<p><p>Cavernous hemangiomas (CHs) are vascular structures comprising abnormally dilated blood vessel clusters. This anomaly is estimated to occur in approximately one out of every 500-600 people.  Individuals often show the first sign of cavernous hemangiomas in their second or third decade. Therefore, the presentation of this disorder is not common in children. This study presents a five year-old-girl who developed abruptly nearly fixed right-sided eye deviation and incoordination after a short course of viral infection. In physical examination, she had left peripheral facial, right eye oculomotor, and left abducens nerve palsy. Her brain's computed tomography (CT) scan revealed hemorrhages in the posterior aspect of the pons and some areas of the hemispheres in different stages. Following brain magnetic resonance imaging (MRI), multiple popcorn ball low-signal T2* lesions with both supra- and infratentorial locations with marked peripheral hypo intensities were seen. These findings were in favor of multiple cavernous hemangiomas of the brain. The novelty of this case was due to observing cavernous angiomas in both supra- and infratentorial spaces in pediatric age.</p>","PeriodicalId":14537,"journal":{"name":"Iranian Journal of Child Neurology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/95/62/ijcn-17-157.PMC10448847.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10107379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric Properties of the Preschool Age Psychiatric Assessment (PAPA) in Farsi: Based on DSM-5.","authors":"Farshid Shahriari, Sanaz Norouzi, Ayyoub Malek, Shahrokh Amiri, Homayoun Sadeghi-Bazargani, Mohammadbagher Hassanzadeh, Helen Link Egger, Brian Small","doi":"10.22037/ijcn.v17i3.36269","DOIUrl":"10.22037/ijcn.v17i3.36269","url":null,"abstract":"<p><strong>Objectives: </strong><b>The</b> first onset of many psychiatric disorders usually occurs in childhood or adolescence. The structured interview of Preschool Age Psychiatric Assessment (PAPA) was developed in response to the need for a standardized and reliable method to assess psychiatric disorders in preschool-age children. This study aimed to translate DSM-5-based PAPA into Farsi and evaluate its face and content validity and reliability.</p><p><strong>Materials & methods: </strong>The procedure was a forward translation of PAPA to Farsi, evaluation for face and content validity, finalization of items within the expert panel, backward translation to English, matching the original PAPA with randomly selected items from the backward translation version, and revision as needed, and finally evaluation for the validity of the changes for localization and cultural considerations. The interviews based on the final Farsi version were performed on thirty parents of children from two to five years old (chosen from Tabriz health centers) to determine the reliability and were repeated at an interval of two weeks.</p><p><strong>Results: </strong> The mean of CVI=0.91 and Modified Kappa=0.90 were obtained, and reliability with Cronbach's alpha was 0.89.</p><p><strong>Conclusion: </strong> The Farsi version of the DSM-5-based PAPA diagnostic interview has good face and content validity and reliability.</p>","PeriodicalId":14537,"journal":{"name":"Iranian Journal of Child Neurology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10704290/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138796506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awareness of Nigerian Mothers on the Risk Factors, Prevention and Management of Seizures in Newborns.","authors":"Oluwatosin Comfort Olarinde,&nbsp;Bayo Lawal Ajibade,&nbsp;Cynthia Adaku Attah,&nbsp;Oluwadamilare Akingbade","doi":"10.22037/ijcn.v17i2.37374","DOIUrl":"https://doi.org/10.22037/ijcn.v17i2.37374","url":null,"abstract":"<p><strong>Objectives: </strong>The study aimed to assess the awareness of mothers on the risk factors, prevention, and management of seizures in newborns.</p><p><strong>Materials & methods: </strong>This descriptive cross-sectional study was conducted on 359 mothers using simple random sampling. The data were collected using questionnaires that included general awareness, awareness of the causes, risk factors, prevention, and management. The data collected were analyzed using frequencies and percentages. Null hypotheses were tested using chi-square at 0.05 level of significance.</p><p><strong>Results: </strong>Two hundred seventy-four mothers (76.3%) had high awareness of seizures in newborns, thirty-four (9.5%) had average awareness, and fifty-one (14.2%) had low awareness. Two hundred seventy-three mothers (76%) had high awareness of the risk factors, and eighty-six (24%) had low awareness, meaning that although some respondents had misconceptions, awareness of the risk factors and causes was good. Two hundred twenty-three (62.1%) respondents had high awareness of preventing seizures in newborns, while 136 (37.9%) had low awareness. The awareness of respondents on managing seizures in newborns is positive, as 291 (81.1%) had high awareness of managing seizures in newborns, while sixty-eight (18.9%) had low awareness. There was a significant relationship between age (<i>p =</i>0.000), marital status (<i>p=</i>0.018), level of education (<i>p =</i>0.000), and awareness of risk factors of seizures in the newborn.</p><p><strong>Conclusion: </strong>A high awareness of neonatal seizures was found among mothers because of their high educational level, although some still had some misconceptions. Improving maternal neonatal seizure awareness and appropriate educational interventions to correct misconceptions are needed.</p>","PeriodicalId":14537,"journal":{"name":"Iranian Journal of Child Neurology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/83/e2/ijcn-17-63.PMC10114276.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9557689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing the Efficacy and Safety of Levetiracetam Versus Phenytoin for Treating the Acute Phase of Neonatal Seizures.","authors":"Mahmoud Mohammadi,&nbsp;Maliheh Kadivar,&nbsp;Razieh Sangsari,&nbsp;Kayvan Mirnia,&nbsp;Maryam Saeedi,&nbsp;Pegah Adhami","doi":"10.22037/ijcn.v17i1.36008","DOIUrl":"https://doi.org/10.22037/ijcn.v17i1.36008","url":null,"abstract":"<p><strong>Objectives: </strong>Neonatal seizure is a significant problem in this life course, and its timely and effective treatment is crucial. In this study, we compared the efficacy of levetiracetam versus phenytoin for treating the acute phase of neonatal seizures.</p><p><strong>Materials & methods: </strong>In this single-blind case-control study, 60 consecutive children with neonatal seizures referred to the Children's medical center in Tehran, Iran, in 2018 were studied. Those neonates who had at least 30 minutes of seizure after Phenobarbital treatment were assigned to receive either phenytoin (20 mg/kg) or levetiracetam (initial dose of 40-60 mg/kg) through block randomization. The efficacy and safety of the two drugs were compared between the groups.</p><p><strong>Results: </strong>The response rate was 83.3% and 86.7% in phenytoin and Levetiracetam groups, respectively, which was not significantly different between groups (P=1.000). Adverse effects were nearly similar between groups (6.7% in the phenytoin group and 3.3% in the Levetiracetam group, P=1.000).</p><p><strong>Conclusion: </strong>Levetiracetam and phenytoin are both practical and safe for treating neonatal seizures.</p>","PeriodicalId":14537,"journal":{"name":"Iranian Journal of Child Neurology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fc/63/ijcn-17-65.PMC9881830.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9229550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors of bruxism in children and adolescents: A case-control study.","authors":"Ahmad Talebian,&nbsp;Mohammad Reza Sharif,&nbsp;Hamid Reza Gilasi,&nbsp;Morteza Ghafeli Bidgoli,&nbsp;Negin Masoudi Alavi","doi":"10.22037/ijcn.v17i2.34695","DOIUrl":"10.22037/ijcn.v17i2.34695","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to investigate the risk factors of bruxism in children and adolescents under 15 years old in Iran.</p><p><strong>Materials & methods: </strong>This case-control study was conducted in day clinics of Shahid Beheshti Hospital in 2020. Fifty children with bruxism in the case group and 50 without in the control group were compared to five risk factors, including intestinal parasites, sucking the fingers, biting objects, a family history of bruxism, and secondhand smoking (SHS). The statistical tests of smoking, odds ratio, and logistic regression were used for data analysis.</p><p><strong>Results: </strong>The mean age of the subjects was 10.6±3.2 and 10.8±2.9 years in the case and control groups, respectively. The bruxism showed significant relation with sucking the fingers, the family history of bruxism, and intestinal parasites. The SHS and biting objects showed no significant relation with bruxism. The logistic regression indicated that the study variables could explain the 22.6 to 30.1% of risk factors in bruxism.</p><p><strong>Conclusion: </strong>Bruxism is a common disorder in children and adolescents. The intestinal parasites might be associated with bruxism. These infestations should be diagnosed and treated in children with bruxism.</p>","PeriodicalId":14537,"journal":{"name":"Iranian Journal of Child Neurology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/46/bf/ijcn-17-081.PMC10448849.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10107381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Causes and Risk Factors of Drug-Resistant Epilepsy in Children.","authors":"Jafar Nasiri,&nbsp;Mohammadreza Ghazzavi,&nbsp;Maryam Sedghi,&nbsp;Zahra Pirzadeh","doi":"10.22037/ijcn.v17i1.33814","DOIUrl":"10.22037/ijcn.v17i1.33814","url":null,"abstract":"<p><strong>Objectives: </strong>Epilepsy, the tendency to have recurrent unprovoked seizures, is the most common chronic neurological disorder worldwide. About 20% to 40% of children with epilepsy suffer from refractory seizures, causing neurological, cognitive, and psychosocial impairments. Identifying the factors contributing to pediatric refractory seizures can help neurologists effectively prevent, diagnose, and treat their patients.</p><p><strong>Materials & methods: </strong>In this cross-sectional study, 2 to 16 years old children with refractory seizures (drug-resistant epilepsy) were assessed regarding their demographic and seizure-associated characteristics.</p><p><strong>Results: </strong>Children with refractory seizures had a significantly higher rate of neonatal asphyxia, hospitalization after birth, neonatal seizures, and seizure in the first year of life, history of infantile spasm, and symptomatic epilepsy. Furthermore, polymorphic seizures and brain MRI abnormalities were significantly more frequent among them. Several different mechanisms have been suggested for explaining intractability in epileptic patients. None of the mechanisms can explain all patients. The most common underlying etiologies for seizures in the intractable group were hypoxic-ischemic damage, cerebral dysgenesis, and genetic disorders.</p><p><strong>Conclusion: </strong>Seizure intractability results from a tremendous deleterious change in the brain's structure. Early identification of the risk factors and prediction of patients likely to have pharmaco-resistant epilepsy will allow more aggressive treatment and earlier specialized intervention.</p>","PeriodicalId":14537,"journal":{"name":"Iranian Journal of Child Neurology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/25/b5/ijcn-17-089.PMC10448845.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10112660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Effectiveness of Risperidone in Treating Breath-Holding Spells in Children.","authors":"Gholamreza Zamani, Alireza Abdi, Morteza Heydari, Mahmoud Reza Ashrafi, Ali Reza Tavasoli","doi":"10.22037/ijcn.v18i1.40320","DOIUrl":"10.22037/ijcn.v18i1.40320","url":null,"abstract":"<p><strong>Objectives: </strong>Breath holding spells (BHS) are a type of syncope in children that is commonly seen in the first years of life. Although these attacks do not cause serious damage to the child's brain, in severe or repeated cases, they expose the brain to hypoxia and cause a lot of stress in parents. In these cases, the clinician should consider therapy. The purpose of this study is to investigate the effectiveness of Risperidone in the treatment of BHS in children visiting the neurology clinic of the Children's Medical Center Hospital.</p><p><strong>Materials & methods: </strong>In this randomized clinical trial, the statistical population included patients with the history of Breath Holding spells grades 2 to 3 (after ruling out of seizure disorders) over one year old, visiting the neurology clinic of Tehran Children's Medical Center in 2019. The subjects were randomly selected from patients visiting the clinic using a table of random numbers from the admit ion list. After providing the necessary explanations and obtaining informed consent from their parents, they were treated with low-dose Risperidone (maximum 1 mg) for three months. The patients were observed for three months in terms of frequency and severity of spells monthly.</p><p><strong>Results: </strong>In this study, the median (25th and 75th percentile) age of subjects was 2.3 (2.0-2.6) years. Both the number and severity of seizures in the subjects had a statistically significant decrease in the period after treatment with Risperidone (P<0.001). The studied boys and girls experienced statistically significant decrease in terms of both the frequency of spells (P-value of 0.002 and 0.039) and intensity of seizures (P=0.016) and P=0.008), respectively after treatment with Risperidone. Also, in the studied children under 2 years old and over 2 years old, both the frequency (P=0.021 and P=0.004) and intensity of spells (P=0.008) 0.016 for subjects under and over 2 years, respectively) had a statistically significant decrease after treatment with risperidone compared to pretreatment.</p><p><strong>Conclusion: </strong>According to the results of this study, it seems that both the frequency and the intensity of spells in children (regardless of gender and age group), experienced a statistically significant decrease after treatment with Risperidone. We suggest conducting a more comprehensive study considering a larger sample size in order to estimate this issue more correctly.</p>","PeriodicalId":14537,"journal":{"name":"Iranian Journal of Child Neurology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10704295/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138796479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of an Exercise Package for Students with Intellectual Disability on Motor and Social Development.","authors":"Ali Kashi,&nbsp;Helen Dawes,&nbsp;Maedeh Mansoubi,&nbsp;Zahra Sarlak","doi":"10.22037/ijcn.v17i1.36644","DOIUrl":"https://doi.org/10.22037/ijcn.v17i1.36644","url":null,"abstract":"<p><strong>Objectives: </strong>Physical activity and reducing inactivity improve health and well-being and benefit young people's social development with an intellectual disability (ID) lasting into adulthood. Therefore, given the importance of encouraging an active lifestyle in adolescents, researchers developed and evaluated the feasibility and potential effect of a novel \"Sport Science Research Institute (SSRI) exercise package for young people with intellectual disability\" to improve the motor and social development of these individuals.</p><p><strong>Materials & methods: </strong>In a Randomised controlled trial between October 2019 to February-2020, Thirty-six 7-18-year-old students with mild intellectual disabilities who were studying in a special school in Tehran received the invitation to the study. Students were randomly divided into intervention (18 students) and control (18 students) groups. Before and after the exercise program, three sessions per week for 12 weeks, motor proficiency was measured using the Bruininks-Oseretsky Test of Motor Proficiency (BOT-2), and social development was measured using the Vineland Social Maturity Scale (VSMS).</p><p><strong>Results: </strong>Pupils in the intervention group completed 92% of the sessions. The results of the ANCOVA test showed that the exercise program led to a statistically significant improvement in total motor proficiency (P<0.01) and total social maturity score (P<0.015).</p><p><strong>Conclusion: </strong>According to this study, the SSRI training package achieved good adherence and increased physical activity and showed the potential to improve motor and social skills in young people with an intellectual disability.</p>","PeriodicalId":14537,"journal":{"name":"Iranian Journal of Child Neurology","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/98/f6/ijcn-17-93.PMC10114272.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9551352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}