国际医药卫生导报最新文献

{"title":"Curative effect report of conservative treatment for small apical cyst","authors":"Qini Zhao","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.23.016","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.23.016","url":null,"abstract":"Objective To study the combined clinical efficacy of sealing agents in simple root canal and gutta-percha root canal filling for treatment of small apical cyst (less than 2 cm in diameter) in anterior tooth.Methods A total of 43 anterior teeth with apical small cyst from 35 cases were studied.All teeth went through adequate drainage,root canals preparation and VITAPEX sealing.Agents were changed fortnightly.During the treatment period,primacaine filling paste combined with gutta-percha was used for root canal filling,according to the shrink status of cyst shown on X-rays of the apical.X-rays following up was performed every six months to track the clinical efficacy after the operations.Results After a two-year-long follow-up,among the 43 teeth with apical cyst,27 teeth healed,12 improved,and 4 failed.The effective rate was 90.69％.Conclusion VITAPEX root canal sealing combined with gutta-percha root canal filling can treat effectively most of small apical cyst in anterior tooth. \u0000 \u0000Key words: \u0000Anterior tooth;  Small apical cyst;  Vitapex;  Root canal filling","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3556-3558"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69926470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A multi-center randomized, placebo-controlled trial of deoxynucleotides and granulocyte colony stimulating factor in treatment of cute cerebral infarction","authors":"Dong-feng Chen","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.23.029","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.23.029","url":null,"abstract":"Objective To evaluate the effectiveness and safety of deoxynucleotide injection in treatment of acute cerebral infarction.Methods Through a multicenter,randomized,single-blind controlled method,144 cases of cerebral infarction patients were enrolled in the control group (n=72) patients who received thrombolysis,anticoagulation,antiplatelet,blood circulation and other standard therapy.Experimental group (n=72) was given deoxynucleotide acid injection (200 mg/d) based on the control group therapy,for continuous 21 days,neurological deficit status of patients was evaluated and serum protein content was detected,and hospital infection rate was also recorded.Results NIHSS scores before and after treatment were significantly decreased in both groups,but the treatment group decreased more significantly compared with the control group (P ＜ 0.05).Barthel indexes before and after treatment were all significantly increased in both groups,but the control group improved more significantly (P ＜ 0.05).The basical recovered rates before and after treatment were 26.0％ and 10.3％,the total efficiency were 91.3％ and 73.5％ respectively,two groups showed statistical significant difference (P ＜ 0.05).Serum protein detection display,TP,ALB levels had decreased to some extent (P ＜ 0.05).After treatment,the TP,ALB levels of the treatment group dropped below the level of the control group,showing a statistical significant difference between the two groups (P ＜ 0.05).After treatment,the 21d,the treatment group CD3+,CD4+,NK cells levels were higher,with a significant difference between the two groups (P ＜ 0.05).Nosocomial infection rates of two groups were 2.9％ and 11.7％ respectively,with a statistical significant difference (x 2=3.979,P=0.046).Conclusion Deoxynucleotide injection can improve neurological impairment of patients,increase their serum protein levels,improve their immunocompetence,and reduce the incidence of nosocomial infection.And it substantially has no adverse reaction during treatment. \u0000 \u0000Key words: \u0000Deoxynucleotide;  Acute cerebral infarction;  Neurological deficit;  Hypoproteinemia","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"14 1 1","pages":"3590-3594"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69926616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on efficacy and safety of paliperidone in the treatment of elderly patients with schizophrenia","authors":"Shi-mei Liu, Xin Duan, Wei Zhang","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.23.030","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.23.030","url":null,"abstract":"Objective To investigate the efficacy and safety of paliperidone and perphenazine tablets in the treatment of eldedy schizophrenia.Methods A total of 63 elderly schizophrenia randomlized into two groups were respectively given Paliperidone or perphenazine for 8 weeks.Clinical effect was evaluated was Positive and Negative Symptom Scale (PANSS),Personal and Social Performance Scale (PSP) and the assessment of adverse drug reaction was evaluated with Traumatic Exposure Severity Scale (TESS).Results The total effective rate was respectively 84.38％ or 80.65％.There were no significant differences in the clinical effect between the two groups.And side effects of Paliperidone were less than perphenazine.Conclusion Paliperidone has good efficacy and high safety in the treatment of elderly schizophrenia patients.So it is beneficial to maintained treatment. \u0000 \u0000Key words: \u0000Paliperidone;  Elderly schizophrenia;  Perphenazine","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3595-3598"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69926656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research progression on application of small molecular targeted drugs for pancreatic cancer","authors":"Xian-ge Huang","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.23.049","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.23.049","url":null,"abstract":"Pancreatic cancer has features of hidden onset,difficult diagnosis at early stage,high malignant degree,high mortality,its incidence has a rising trend globally.The cytotoxic drugs such as gemcitabine are still the mainstream standard chemotherapy drugs for pancreatic cancer treatment,but the efficacy is not ideal.Seeking new targeted therapy and studying targeted drugs in combination with cytotoxic drugs to improve treatment effect and the quality of life is the current concerned direction.This article is going to introduce the targeted drugs which has positive results in treatment of pancreatic cancer in recent years,it illustrates the research progress on the mechanism of action of targeted drugs according to the properties of molecular targeted spots. \u0000 \u0000Key words: \u0000Pancreatic cancer;  Gemcitabine;  Small molecular targeted drugs","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3655-3659"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69927157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"心理干预对减轻TACE术治疗巨块型肝癌患者负性情绪的作用研究","authors":"李惠香, 李胜新, 黄素琴, 罗云藩, 王革","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.23.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.23.012","url":null,"abstract":"目的 探讨心理干预对减轻TACE术治疗巨块型肝癌患者负性情绪的作用.方法 将我院收治的100例巨块型肝癌行TACE术患者随机分为实验组与对照组各50例.对照组采用常规护理措施,包含入院宣教、术前指导、术后常规护理及健康指导等;实验组在对照组基础上采用心理干预措施进行护理,主要包含术前针对性的心理护理,术后手术说明,心理-行为计划,心理舒适护理,相关症状的心理护理等.采用SAS、SDS量表评价患者的焦虑及抑郁状况,采用SCL-90量表评价患者的负面心理状况.结果 干预4周后实验组的SAS评分及SDS评分显著低于对照组[(44.2±7.7)vs.(50.7±8.0);(40.2±6.8)vs.(48.6±8.1)](P＜0.01);干预4周后实验组患者的躯体化、强迫症状、抑郁、焦虑、恐怖、敌对及其它因子评分显著低于对照组干预4周后水平(P＜0.05).结论 巨块型肝癌行TACE手术存在明显的心理负面情绪,临床上应根据患者不同的心理状况及诱因给予针对性的心理护理干预,提升其生活质量。","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"15 1","pages":"3543-3546"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69926779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis on intervention effect of community health care measures for postpartum women","authors":"Y. Ye, Ranglan Zhuo, Li-xin Lin","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.23.043","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.23.043","url":null,"abstract":"Objective To explore and analyze the application value of community health care measures in nursing intervention for puerperal women.Methods 300 cases of puerperal women in a community survey from October 2012 to October 2013 were chosen as the research objects,they were divided into the observation group and the control group,150 cases in each group,the observation group was given maternal nursing intervention and the community health care measures,the control group used conventional nursing measures,the maternal complications of two groups were observed and compared.Results After the nursing intervention the incidence of obstetric complications in observation group was 3.3％,while in the control group it was 20.0％,showing statistical significant difference (P ＜ 0.05).Conclusion Community health care nursing intervention is helpful to promote physical recovery after the puerpera labors,reduce the incidence of maternal postpartum complications,so as to improve the quality of life of women,which is worthy of clinical application. \u0000 \u0000Key words: \u0000Community health care measures;  Puerperium;  Postpartum complications;  Nursing intervention","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3637-3639"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69927045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of vitrification method on clinical outcome of human frozen-thawed cleaved embryo transfer","authors":"Qianru Liu, Qi-jian Huang, Linsheng Chi, Jing-ti Zhang, Li Zhu","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.23.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.23.008","url":null,"abstract":"Objective To investigate the influence of vitrification method on clinical outcome of human frozen-thawed cleaved embryo transfer.Methods In the in vitro fertilization and embryo transfer cycles,supernumerary embryos were cryopreserved by vitrification or slow-freezing sequencing method.The embryo survival rate,intact survival rate,pregnant rate and implantation rate were compared after thawing.Results In 248 vitrified embryo thaw cycles,746 vitrified embryos were thawed,and 643(86.2％) of them survived and 594(79.4％) of them intactly survived after the thawing.In 244 women,632 embryos were transferred,and 107(43.9％) of them got clinical pregnancy,the implantation rate was 26.1％ (165/632).As to slow-freezing method,in 225 embryo thaw cycles,818 embryos were thawed,598 (73.1％) of them survived,436(53.3％) of them intactly survived,and 594 embryos were transferred in 225 cycles,and 74 (32.9％) of them got clinical pregnancy,the implantation rate was 15.2％(90/594).The embryo survival rate,intact survival rate,pregnant rate,implantation rate were higher in vitrification group than those in slow-freezing group (P ＜ 0.05).Conclusion Vitrification is a more effective method of cryopreserving the human embryo than conventional slow freezing. \u0000 \u0000Key words: \u0000Vitrification;  Slow-freezing sequencing;  Cleaved embryo;  In vitro fertilization and embryo transfer","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3531-3534"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69926766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinic effect of applying tirofiban on high and moderate-risk NSTE-ACS patients after a successful percutaneous coronary intervention treatment","authors":"Su-Ping Ma","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.23.017","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.23.017","url":null,"abstract":"Objective To study how tirofiban (one kind of anti-platelet concentration drugs) reacts on non-ST-segment elevated acute coronary syndromes (NSTE-ACS) patients who were at moderate or high risk after percutaneous coronary intervention (PCI).Methods After operating PCI on the moderate or high risk NSTE-ACS patients in our hospital,the author divided these patients into observation group and control group.The control group was injected with normal saline,while the observation group was injected with tirofiban.After the injection,the safety and the effectiveness of the two groups were compared.Results After30 days of the operation,there was no remarkable difference of effectiveness endpoint between the two groups (P=0.40).There was no significant difference of composite endpoint after 7 days and 6 months as well.However,after 6 months the survival rate of the observation group was much higher than that of the control group (99.2％ vs 94.2％,log-rank P=0.03).Besides,the safety rates of the two groups had no significant difference.Conclusion After PCI,if the moderate or high risk NSTE-ACS patients are injected with tirofiban as the anti-platelet drug,the survival rate can be increased and the treatment is quite reliable. \u0000 \u0000Key words: \u0000Acute coronary syndromes;  Percutaneous coronary intervention;  Anti-platelet concentration drugs","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3559-3562"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69926514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and radiographic features analysis on Caroli's disease","authors":"Zhe Sun, Junxiang Zhang","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.23.037","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.23.037","url":null,"abstract":"Objective To analyze the clinical and radiographic features of Caroli's disease,and to explore the value of CT and MRI in the diagnosis of Caroli's disease,in order to improve diagnostic level of this disease.Methods ① We retrospectively analyzed the clinical data of 11 cases of Caroli's disease patients,which were pathologically confirmed as Caroli's disease,from January 2009 to January 2014 in the First Affiliated Hospital of Bengbu Medical College and the Second Affiliated Hospital of Anhui Medical University.② According to 357 cases reported in the literature we analyzed the clinical and radiological features.Results ① In 11 cases,the male vs female ratio was 1∶1.2,the average age of diagnosis was 46.6 years old,4 of 11 cases were type Ⅰ,the other 7 cases were type Ⅱ; the main clinical manifestations were repeated right upper quadrant pain or discomfort,fever,jaundice,portal hypertension.Overall,4 cases were combined with bile duct stones,2 cases combined with renal cyst,3 cases showed \"Sac tail sign\",3 cases showed \"central dot sign\",6 cases had \"hanging sign\".② Combined with the reported 368 cases of Caroli's disease patients,the male vs female ratio was 1:1.01,the average age of diagnosis was 34.7 years old,48.4％ with type Ⅰ,51.6％ with type Ⅱ; 49.1％ combined with bile duct stones,18.1％ with renal cystic disease; the occurrence rate of \"Sac tail sign\",\"central dot sign\" and \"hanging sign\" were 44.3％,43.8％ and 86.2％ respectively.Conclusion Caroli's disease has no significant gender differences,type Ⅱ more slightly than type Ⅰ,the most common complication was duct stones,and the \"Sac tail sign\",\"central dot sign\" and \"hanging sign\" are the significant radiographic features of Caroli's disease.These clinical and radiological features can improve the diagnosis of Caroli's disease. \u0000 \u0000Key words: \u0000Caroli's disease;  Imaging diagnosis","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3616-3621"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69926797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"品管圈在儿科输液服务流程改进中的应用","authors":"孟凡峰, 崔传英","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.23.047","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.23.047","url":null,"abstract":"目的 评价品管圈活动(QCC)对于儿科输液服务流程改进中的临床效果.方法 建立“输液服务流程改进品管圈”,通过对2012年6至7月间,即品管圈成立前2个月间于我院儿科就诊的患儿家长80例进行问卷调查,了解输液服务流程的现状并分析原因,制定并实施相应的护理对策后,观察2012年8至9月间的患儿家长对护理的满意度以及评价24例品管圈护理人员的护理综合能力改变状况,已评价品管圈活动对儿科输液服务流程改进中的临床效果.结果 随着“输液服务流程改进品管圈”活动的开展,患儿家长对输液各环节的护理满意度显著升高(P＜0.05);输液服务流程改进后,患儿等待输液的时间与输液服务流程改进前相比,输液等待时间显著减少(t=11.479,P=0.014);通过对护理人员综合能力的评测发现,护理人员的各项护理能力均较改进前显著提升(P＜ 0.05).结论 品管圈活动的开展,促进了护理人员的积极性和自信心的建立,提高了护理人员的技能,提升了患者对于护理的满意度。","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3649-3652"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69927114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}