国际医药卫生导报最新文献_第9页

Predictive value of cervical fetal fibronectin in the first trimester pregnancy outcome of recurrent spontaneous abortion 宫颈胎儿纤维连接蛋白对妊娠早期复发性自然流产结局的预测价值

国际医药卫生导报 Pub Date : 2014-12-01 DOI: 10.3760/CMA.J.ISSN.1007-1245.2014.23.001

S. Fu, Xin Chen, L. Meng, Hui Chen, Jian-ping Tan, Yinglin Liu, Rui Zhang

{"title":"Predictive value of cervical fetal fibronectin in the first trimester pregnancy outcome of recurrent spontaneous abortion","authors":"S. Fu, Xin Chen, L. Meng, Hui Chen, Jian-ping Tan, Yinglin Liu, Rui Zhang","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.23.001","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.23.001","url":null,"abstract":"Objective To discuss the clinical value of fetal fibronectin when predicting the first-trimester fatal loss in recurrent miscarriage.Methods We measured fetal fibronectin concentrations in cervical and vaginal secretions in 84 cases of recurrent miscarriage admitted in our hospital from 2008 to 2011 as observation group.And we also tested it in 31 uncomplicated pregnant women.Tests were given in first-trimester.Age and previous miscarriage number were also compared.Follow-up was given till 14 weeks of pregnancy.Results In observation group,57.14％ of patients were tested by positive fFN results,while in control group,the percentage reduced to 12.90％.It had statistical significant difference (P ＜ 0.01).In positive fFN patients,29.17％ leaded to fatal loss in observation group,while 8.33％ in control group (P ＜ 0.05).The sensitivity and accuracy for predicting miscarriage by fFN test in recurrent miscarriage in first-trimester were 82.35％ and 49.25％.Positive fFN could be found more in women over 35 years old and in women under age of 35 years.Conclusion The presence of cervicovaginal fetal fibronectin in the second and third trimesters of pregnancy identifies a subgroup of women who are at high risk of recurrent miscarriage.The measure of cervical fetal fibronectin had great sensitivity in first-trimester to predict the fatal loss,particularly for women aged over 35 years. \u0000 \u0000Key words: \u0000Fetal fibronectin; Recurrent spontaneous abortion; Early pregnancy","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3505-3508"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69926543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between properties of carotid plaques and common risk factors among community high-risk population 社区高危人群颈动脉斑块特征与常见危险因素的关系

国际医药卫生导报 Pub Date : 2014-12-01 DOI: 10.3760/CMA.J.ISSN.1007-1245.2014.23.003

Fei-Yan Li, P. Qi, Y. Zhuang, Yiwen Chen, Hejin Lv, Meixing Huang

{"title":"Relationship between properties of carotid plaques and common risk factors among community high-risk population","authors":"Fei-Yan Li, P. Qi, Y. Zhuang, Yiwen Chen, Hejin Lv, Meixing Huang","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.23.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.23.003","url":null,"abstract":"Objective To investigate the relationship between properties of carotid plaques and common risk factors among community high-risk population.Methods From January 2008 to August 2010,the data of 235 subjects from atherosclerotic high-risk population in local communities were collected.The carotid plaques of the subjects were confirmed by color ultrasound.Univariate and multivariate analyses were used to identify the relationship between the properties of carotid plaques (flat,soft,hard and ulcer plaque) and the common risk factors.Results Univariate analyses showed that subjects over 80 years old had much more ulcer plaques than younger ones (P=0.042); females and hypertensive subjects had significantly more soft plaques than males and non-hypertensive ones separately (P=0.000 and P=0.027,respectively).Multivariate analyses discovered that age (older) and systolic blood pressure (SBP) were the key risk factors influencing ulcer plaque formation (ORase=1.043,P=0.030 and ORSBP=1.026,P=0.024,respectively); female and SBP were the protective factors influencing the soft plaque formation (ORsex=0.321,P=0.000 and ORSBP=0.970,P=0.006,respectively).Conclusion Female and hypertensive patients have less soft carotid plaques,and those over 80 years old have more ulcer plaques. \u0000 \u0000Key words: \u0000Carotid plaque; Risk factor; High-risk population","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3513-3516"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69926620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combinatorial diagnostic value of DcR3, Bcl-2 and PCNA in bladder cancer tissues DcR3、Bcl-2和PCNA在膀胱癌组织中的组合诊断价值

国际医药卫生导报 Pub Date : 2014-12-01 DOI: 10.3760/CMA.J.ISSN.1007-1245.2014.23.005

D. Lan

{"title":"Combinatorial diagnostic value of DcR3, Bcl-2 and PCNA in bladder cancer tissues","authors":"D. Lan","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.23.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.23.005","url":null,"abstract":"Objective To explore the combinatorial diagnostic value of Decoy receptor 3 (DcR3),B-cell lymphoma-2 (Bcl-2) and proliferating cell nuclear antigen (PCNA) in bladder cancer tissues.Methods Immunohistochemistry (IHC) was performed to detect the expression of DcR3,Bcl-2 and PCNA in 224 cases bladder cancer tissues and 56 cases normal bladder tissues.Receiver operating characteristic (ROC) curve was applied to analyze the clinicopathological diagnostic value of the aforementioned 3 biomarkers individually or combinatorially.Results The expressions of DcR3,Bcl-2 and PCNA in bladder cancer were significantly higher than those in normal control (all P ＜ 0.05).The DcR3 level had positive correlations with pathological stages,invasion,lymphatic metastasis and recurrence (all P ＜ 0.05).The expression of Bcl-2 was related to lymphatic metastasis in bladder cancer (P ＜ 0.05).The expression of PCNA had a correlation with pathological stage and lymphatic metastasis (both P ＜ 0.05).DcR3 expression level was associated with that of Bcl-2 and PCNA,whereas Bcl-2 also had consistent correlation with PCNA (P ＜ 0.05).The areas under the curve (AUCs) of DcR3,Bcl-2 and PCNA were higher than the individual level of each marker.The combination of DcR3+PCNA,Bcl-2+PCNA and DcR3+Bcl-2+PCNA offered higher sensitive values than single marker.The highest sensitive value was 0.830,produced by the combination of DcR3+Bcl-2+PCNA.The combination of DcR3+PCNA (100％),Bcl-2+PCNA (96.2％) and DcR3+Bcl-2+PCNA (100％) had higher positive predictive values than single markers.Conclusion Combined detection by immunohistochemistry of DcR3,Bcl-2 and PCNA could noticeably improve the sensitivity and positive predictive values in the diagnosis of bladder cancer,which is superior to individual marker. \u0000 \u0000Key words: \u0000Bladder cancer; Decoy receptor 3; B-cell lymphoma-2; Proliferating cell nuclear antigen; Immunohistochemistry; Receiver operating characteristic curve","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3520-3525"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69926631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

国际医药卫生导报 Pub Date : 2014-12-01 DOI: 10.3760/CMA.J.ISSN.1007-1245.2014.23.019

刘子红

{"title":"老年腔隙性脑梗死后影响认知功能障碍的相关因素分析","authors":"刘子红","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.23.019","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.23.019","url":null,"abstract":"目的探讨影响老年腔隙性脑梗死患者认知功能障碍的主要危险因素,为老年腔隙性脑梗死的早期预防和干预提供依据.方法将102例腔隙性脑梗死老年患者列为观察组,并选择84例非腔隙性脑梗死患者为对照组,使用蒙特利尔认知评估量表(MoCA)进行认知功能评估,比较两组认知功能评分和认知功能障碍率.观察组患者在入院1年后再行评估,比较入院时和1年后的评分变化,并采用logistic回归分析总结危险因素.结果观察组视空间与执行功能、注意力、语言、延迟回忆和认知功能总分分别为(3.25±0.83)、(4.45±0.71)、(2.26±0.61)、(2.58±1.31)、(22.64±2.91),均显著低于对照组(P＜0.05).观察组认知功能认知障碍率为50.98％,显著高于对照组(x2=8.745,P＜0.001).观察组1年后认知功能评分为(22.51±3.23),与入院时比较差异无统计学意义(t=1.325,P=0.396).其中26例患者在1年后MoCA评分显著下降(t=3.983,P=0.033).logistic回归结果显示糖尿病、高脂血症是导致老年腔隙性脑梗死患者认知功能障碍的主要危险因素(P值分别为0.034、0.011).结论老年腔隙性脑梗死患者存在一定的认知功能障碍.部分患者随着病程的延长,认知功能障碍有加重的趋势.与高血压、颈动脉斑块、吸烟史相比,合并糖尿病、高脂血症的老年腔隙性脑梗死患者更容易发生认知功能障碍。","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3565-3568"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69926553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application value of plasma brain natriuretic peptide in the diagnosis and treatment of patients with heart failure 血浆脑利钠肽在心力衰竭患者诊治中的应用价值

国际医药卫生导报 Pub Date : 2014-12-01 DOI: 10.3760/CMA.J.ISSN.1007-1245.2014.23.020

Fenling Hong

引用次数: 0

甲泼尼龙治疗儿童难治性肺炎支原体肺炎的临床效果分析甲泼尼龙治疗儿童难治性肺炎支原体肺炎的临床效果分析

国际医药卫生导报 Pub Date : 2014-12-01 DOI: 10.3760/CMA.J.ISSN.1007-1245.2014.23.028

常会娟, 李会娟, 靳秀红

引用次数: 0

风险管理在精神科开放式管理中的应用风险管理在精神科开放式管理中的应用

国际医药卫生导报 Pub Date : 2014-12-01 DOI: 10.3760/CMA.J.ISSN.1007-1245.2014.23.045

武艳红, 苏献红, 李晋华

引用次数: 0

Application of evidence nursing intervention for radiation reaction of nasopharyngeal carcinoma patients at later period 循证护理干预在鼻咽癌晚期放射反应中的应用

国际医药卫生导报 Pub Date : 2014-12-01 DOI: 10.3760/CMA.J.ISSN.1007-1245.2014.23.042

Cai-feng Chen, W. Yi, Guang-qing Liu

{"title":"Application of evidence nursing intervention for radiation reaction of nasopharyngeal carcinoma patients at later period","authors":"Cai-feng Chen, W. Yi, Guang-qing Liu","doi":"10.3760/CMA.J.ISSN.1007-1245.2014.23.042","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1007-1245.2014.23.042","url":null,"abstract":"Objective To investigate the nursing of anxiety and radiation reaction degree of radiation treatments in nasopharyngeal carcinoma (NPC) patients at the late period.Methods 68 patients pathologically diagnosed as NPC who received radiotherapy for about six weeks,used the application of self design as ＜the survey of patients with systemic and local reactions in late radiation therapy ＞ and symptoms of anxiety scale test (SAS) to analyze the questions and seek evidence nursing intervention,according to the individual problems.Results The problems of patients were as follows:① dizziness,fatigue,how to conduct anti-fall care? ② Oral mucosal inflammation and ulcerative reaction,how to effectively prevent and reduce oral mucosa reaction and oral fungal infection? ③ Producing negative reaction,such as different degrees of anxiety,how to carry out psychological intervention? We should obtain randomized controlled trials,systematic reviews and Meta-analysis of documentary evidence,the patients satisfaction rate accounted for 79.4％-98.5％,anxiety reaction was lower than the psychological counseling,the statistical significance was (t=20.431,P ＜ 0.01).Conclusion For NPC patients with radiation reaction,using evidence nursing can effectively reduce the radiation complications,and alleviate the anxiety of patients. \u0000 \u0000Key words: \u0000Nasopharyngeal carcinoma; Radiation reaction; Evidence; Intervention","PeriodicalId":14405,"journal":{"name":"国际医药卫生导报","volume":"20 1","pages":"3634-3637"},"PeriodicalIF":0.0,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69926873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

老年子宫内膜癌组织中信号转导与转录活化因子3的表达研究老年子宫内膜癌组织中信号转导与转录活化因子3的表达研究

国际医药卫生导报 Pub Date : 2014-12-01 DOI: 10.3760/CMA.J.ISSN.1007-1245.2014.23.014

邓鹏飞, 左艳

引用次数: 0

The application value of low frequency pulse electrodiagnosis in the assessment of facial nerve paralysis 低频脉冲电诊断在面神经麻痹评估中的应用价值

国际医药卫生导报 Pub Date : 2014-12-01 DOI: 10.3760/CMA.J.ISSN.1007-1245.2014.23.006

Yinhai Chen, Jinghua He

引用次数: 0