International Journal of Reproductive Biomedicine最新文献

{"title":"Role of platelet-rich plasma in pelvic floor disorders: A systematic review.","authors":"Eighty Mardiyan Kurniawati, Nur Anisah Rahmawati, Gatut Hardianto, Hari Paraton, Tri Hastono Setyo Hadi","doi":"10.18502/ijrm.v21i12.15034","DOIUrl":"10.18502/ijrm.v21i12.15034","url":null,"abstract":"<p><strong>Background: </strong>Management for pelvic floor disorders needs to be improved. Platelet-rich plasma (PRP) offers an innovative treatment in general medical care to promote cell regeneration.</p><p><strong>Objective: </strong>This review aims to investigate the role of PRP in pelvic floor disorders.</p><p><strong>Materials and methods: </strong>6 international databases were accessed using several keywords namely PubMed, Science Direct, Cochrane Library, ProQuest, Google Scholar, and Scopus. The inclusion criteria were articles written in English, published in 10-yr period from 2012 until 2022, and investigated the relevant topic. This systematic review followed PRISMA guideline.</p><p><strong>Results: </strong>644 articles were found in several databases and 15 articles met the criteria. Management for pelvic floor disorders needs to be improved, but there are still many challenges, such as less effective treatments, risk of recurrence, and postoperative wound healing. PRP offers an innovative treatment in general medical care to promote cell regeneration. A total of 644 articles from the database were found, but 15 studies met the criteria. A total of 600 women with various pelvic floor disorders treated with PRP were analyzed. PRP positively impacts female sexual dysfunction, perineal trauma, vulvovaginal atrophy, stress urinary incontinence, vesicovaginal fistula, perineal rupture, and pelvic organ prolapse. Dosages, preparation techniques, injection techniques, and additive materials are varied. Most studies do not report side effects from the therapy, but the urinary disorder complaints must be paid attention to.</p><p><strong>Conclusion: </strong>PRP can be used to manage pelvic floor disorders. Future studies should clarify and standardize the dose in each case and how to make PRP produce the best results.</p>","PeriodicalId":14386,"journal":{"name":"International Journal of Reproductive Biomedicine","volume":"21 12","pages":"957-974"},"PeriodicalIF":1.3,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10869963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139899870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex assignment and psychosexual peculiarities of individuals with different forms of androgen insensitivity syndrome: A qualitative study.","authors":"Jenaro Kristesashvili, Levan Kobaladze, Mariam Chipashvili, Anna Jibladze","doi":"10.18502/ijrm.v21i12.15036","DOIUrl":"10.18502/ijrm.v21i12.15036","url":null,"abstract":"<p><strong>Background: </strong>A mismatch between chromosomal, gonadal, and phenotypic sexes in individuals with androgen insensitivity syndrome (AIS) creates problems in sex assignment and psychosexual identification.</p><p><strong>Objective: </strong>To identify psychosexual and sex assignment peculiarities of individuals with different forms of AIS.</p><p><strong>Materials and methods: </strong>In this qualitative study, 41 individuals with AIS aged between 15 and 31 yr who referred to the Universe Center for Reproductive Medicine Tbilisi, Georgia between 2016 and 2021 were studied. All individuals underwent clinical, genealogical, hormonal, ultrasonographic, and cytogenetic examinations. In-depth interviews and medical records assessed psychosexual profiles and sex assignment histories.</p><p><strong>Results: </strong>32 cases were diagnosed with the complete form of AIS (CAIS), 8 individuals with the partial form (PAIS), and one with a mild form (MAIS). Individuals with CAIS and PAIS were assessed at birth and raised as girls. Individuals with CAIS and female psychosexual disposition were referred to us due to amenorrhea. Adolescent individuals with PAIS assessed as girls referred to us due to masculinization detected in puberty. An individual with MAIS was assessed at birth and raised as a boy with male genitalia. All individuals with AIS had typical hormonal data and sex chromosome complex for men. 20 sexually active individuals with CAIS had penile-vaginal contact with the man. None of the individuals with CAIS and PAIS thought about gender reassignment after being diagnosed, only the individual with MAIS aimed for male-to-female transition.</p><p><strong>Conclusion: </strong>Psychosexual identification remains a significant challenge in AIS management. Detection of female psychosexual disposition in one participant that is unusual to MAIS may be associated with somatic mosaicism of the androgen receptor gene.</p>","PeriodicalId":14386,"journal":{"name":"International Journal of Reproductive Biomedicine","volume":"21 12","pages":"985-994"},"PeriodicalIF":1.3,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10869957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139899871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does body mass index compromise assisted reproductive technique outcomes? A cross-sectional study.","authors":"Fereshteh Bahrami, Saeideh Dashti, Esmat Mangoli, Hanie Sadat Hosseini","doi":"10.18502/ijrm.v21i12.15040","DOIUrl":"10.18502/ijrm.v21i12.15040","url":null,"abstract":"<p><strong>Background: </strong>Overweight and obese people face several health problems. Female obesity has been shown to reduce fertility in the general population. Assisted reproductive technology outcomes in obese cases are widely studied, but the results are inconclusive.</p><p><strong>Objective: </strong>This study aimed to compare live birth rate (LBR) among women with 4 different types of body mass index (BMI).</p><p><strong>Materials and methods: </strong>In this cross-sectional study, data of 1611 women, who were candidates for fresh and frozen embryo transfer cycles, was extracted from 2051 medical files at the Reproductive Sciences Institute, Yazd, Iran from May 2019-May 2021. The participants were divided into 4 groups (underweight, normal, overweight, and obese) according to their BMI, and LBR was considered to be the main outcome.</p><p><strong>Results: </strong>Of 1611 women, 39 were underweight, 585 were normal, 676 were overweight, and 311 were obese. Underweight women had the lowest LBR (12.8%), but there was no statistically significant difference (p = 0.55). In addition, LBR was compared in the 4 BMI groups according to age, type of transfer cycle (fresh or freeze), and cause of infertility, and there was comparable LBR in the 4 BMI groups. However, metaphase 2 oocyte rate, doses of gonadotropin usage in the cycles, and estradiol level had statistically significant differences (p <math><mo><</mo></math> 0.001).</p><p><strong>Conclusion: </strong>According to our study, obesity does not affect LBR in the IVF cycle, regardless of fresh or frozen embryo transfer cycles, different age groups, and causes of infertility.</p>","PeriodicalId":14386,"journal":{"name":"International Journal of Reproductive Biomedicine","volume":"21 12","pages":"1021-1030"},"PeriodicalIF":1.3,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10869964/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139899867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A hybrid feature selection algorithm to determine effective factors in predictive model of success rate for in vitro fertilization/intracytoplasmic sperm injection treatment: A cross-sectional study.","authors":"Ameneh Mehrjerd, Hassan Rezaei, Saeid Eslami, Nayyere Khadem Ghaebi","doi":"10.18502/ijrm.v21i12.15038","DOIUrl":"10.18502/ijrm.v21i12.15038","url":null,"abstract":"<p><strong>Background: </strong>Previous research has identified key factors affecting in vitro fertilization or intracytoplasmic sperm injection success, yet the lack of a standardized approach for various treatments remains a challenge.</p><p><strong>Objective: </strong>The objective of this study is to utilize a machine learning approach to identify the principal predictors of success in in vitro fertilization and intracytoplasmic sperm injection treatments.</p><p><strong>Materials and methods: </strong>We collected data from 734 individuals at 2 infertility centers in Mashhad, Iran between November 2016 and March 2017. We employed feature selection methods to reduce dimensionality in a random forest model, guided by hesitant fuzzy sets (HFSs). A hybrid approach enhanced predictor identification and accuracy (ACC), as assessed using machine learning metrics such as Matthew's correlation coefficient, runtime, ACC, area under the receiver operating characteristic curve, precision or positive predictive value, recall, and F-Score, demonstrating the effectiveness of combining feature selection methods.</p><p><strong>Results: </strong>Our hybrid feature selection method excelled with the highest ACC (0.795), area under the receiver operating characteristic curve (0.72), and F-Score (0.8), while selecting only 7 features. These included follicle-stimulation hormone (FSH), 16Cells, FAge, oocytes, quality of transferred embryos (GIII), compact, and unsuccessful.</p><p><strong>Conclusion: </strong>We introduced HFSs in our novel method to select influential features for predicting infertility success rates. Using a multi-center dataset, HFSs improved feature selection by reducing the number of features based on standard deviation among criteria. Results showed significant differences between pregnant and non-pregnant groups for selected features, including FSH, FAge, 16Cells, oocytes, GIII, and compact. We also found a significant correlation between FAge and fetal heart rate and clinical pregnancy rate, with the highest FSH level (31.87%) observed for doses ranging from 10-13 (mIU/ml).</p>","PeriodicalId":14386,"journal":{"name":"International Journal of Reproductive Biomedicine","volume":"21 12","pages":"995-1012"},"PeriodicalIF":1.3,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10869959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139899865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased expression level of <i>Dicer</i> in placenta is associated with the early onset of preeclampsia.","authors":"Fatemeh Mohseni, Mohammad Shekari, Kianoosh Malekzadeh, Pooneh Nikuei, Fatemeh Poordarvish, Ali Atashabparvar, Kourosh Bamdad","doi":"10.18502/ijrm.v21i12.15043","DOIUrl":"10.18502/ijrm.v21i12.15043","url":null,"abstract":"","PeriodicalId":14386,"journal":{"name":"International Journal of Reproductive Biomedicine","volume":"21 12","pages":"1031-1034"},"PeriodicalIF":1.3,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10869960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139899868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parental consanguinity and ovarian reserve: A retrospective cohort study.","authors":"Shadya Al Saeghi, Tamadhir Al-Mahrouqi, Maha Al-Khadhuri, Rahma Al-Ghabshi, Jokha Al-Sabti, Sachin Jose, Vaidyanathan Gowri","doi":"10.18502/ijrm.v21i12.15039","DOIUrl":"10.18502/ijrm.v21i12.15039","url":null,"abstract":"<p><strong>Background: </strong>Infertility affects around 10-15% of couples worldwide and is both a social and medical problem. Parental consanguinity is considered to reduce fertility reserve. Consanguineous marriages, especially first cousin marriages, are very common in Oman according to the Oman National Health Survey data.</p><p><strong>Objective: </strong>This study aimed to determine whether women born to consanguineous parents have reduced ovarian reserve.</p><p><strong>Materials and methods: </strong>This cohort study was conducted on 414 women aged <math><mo>≤</mo></math> 39, treated for infertility at Sultan Qaboos University hospital and Royal hospital, Muscat, Oman from January 2019-December 2020. Each participant was interviewed and a complete history, including parental consanguinity and physical examination, were recorded. On day 2 of the menstrual cycle, serum concentration of the following was performed: follicle-stimulating hormone (FSH), luteinizing hormone, estradiol, prolactin, thyroid stimulating hormone, and anti-Müllerian hormone (AMH). AMH was done, if necessary, on other days of the cycle. Antral follicle count (AFC) was done on day 2 and 3 of the menstrual cycle.</p><p><strong>Results: </strong>Of the 414 women, parental consanguinity was present in 40.2% of couples. In women with low AFC, parental consanguinity was present in 15.3% compared to 13.0% in the non-consanguineous group. About 15% of women with low AMH had consanguineous parents, compared to 20.2% from the non-consanguineous group. High levels of FSH were present in 6.5% and 4.2% of the consanguineous and non-consanguineous groups, respectively. No significant difference was observed in AFC with reference to body mass index.</p><p><strong>Conclusion: </strong>The results from this study showed no statistically significant difference in low ovarian reserves (AFC, AMH, and FSH) in women whose parents had a consanguineous marriage.</p>","PeriodicalId":14386,"journal":{"name":"International Journal of Reproductive Biomedicine","volume":"21 12","pages":"1013-1020"},"PeriodicalIF":1.3,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10869961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139899869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The male-focused marital relationship enrichment and sexual well-being interventions: A scoping review.","authors":"Solmaz Abdollahzadeh Sardehaei, Effat Merghati Khoei, Beheshteh Niusha, Zahed Rezaei","doi":"10.18502/ijrm.v21i12.15035","DOIUrl":"10.18502/ijrm.v21i12.15035","url":null,"abstract":"<p><strong>Background: </strong>There is an increasing need for sexual well-being and health promotion strategies that effectively engage men. Researchers have evaluated the efficacy of sexual and reproductive health-related and marital enhancement interventions in male-dominated societies. However, few have focused on culturally appropriate and gender-specific program effects.</p><p><strong>Objective: </strong>This review aims to evaluate evidence of existing interventions aimed at enriching marital relationships and sexual well-being in adult men.</p><p><strong>Materials and methods: </strong>This scoping review was conducted by searching various databases (CINAHL, PsycINFO, EMBASE, Google Scholar, PubMed, Scopus, SID, and Noormags), and other available resources in both English and Persian languages. We located all publications up to January 2023 with no time restriction. Inclusion criteria were studies targeting men in the enrichment of marital and sexual relationships, which focus on marital/sexual enrichment, sexual and reproductive health (SRH) program, passionate relationship, or sexual satisfaction as the main outcomes. PRISMA guidelines were utilized in this review.</p><p><strong>Results: </strong>Of records 34,405 retrieved by searching, after removing duplicate articles, 8 articles were included based on the inclusion criteria. SRH program was the main focus of 6 articles. Marital and sexual enhancement were common areas of focus in 2 studies. Research methods included 2 semi-experimental, 3 clinical trials, 1 systematic review, 1 content analysis, and a mixed method. According to the assessment result, 4 articles were moderate and 4 were of high quality.</p><p><strong>Conclusion: </strong>Our findings reveal that a small number of interventions specifically offering SRH or marital and sexual enhancement programs to men should be conducted. As the majority were heterosexual couples, we recommend male-focused programs recognizing men's sexuality.</p>","PeriodicalId":14386,"journal":{"name":"International Journal of Reproductive Biomedicine","volume":"21 12","pages":"975-984"},"PeriodicalIF":1.6,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10869958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139899872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of antibiotic therapy and transvaginal ultrasound-guided efficacy of transvaginal ultrasound-guided drainage in treating tubo-ovarian abscesses: Three case reports.","authors":"Zahra Heidar, Tayebeh Esfidani, Atefeh Moridi, Mahtab Anvari","doi":"10.18502/ijrm.v22i11.17825","DOIUrl":"10.18502/ijrm.v22i11.17825","url":null,"abstract":"<p><strong>Background: </strong>To introduce minimally invasive methods for the successful treatment of tubo-ovarian abscesses (TOAs), an antibiotic regimen was considered the first line of treatment. However, in some cases, this approach fails, and another intervention (laparotomy or minimally guidance drainage) is required.</p><p><strong>Case presentations: </strong>3 women with a history of long-time infertility, all of them were candidates for in vitro fertilization referred to the obstetrics and gynecology department with similar manifestations. For these 3 cases (30-40 yr) the first approach was a broad-spectrum antibiotic therapy. In 2 cases the last step in treatment was transvaginal ultrasound guidance drainage, and in one case laparotomy was done after antibiotic regimen failure; however, in all of 3 cases the best results were seen in transvaginal ultrasound guidance drainage.</p><p><strong>Conclusion: </strong>Patients who have ovarian endometrioma and undergo an assisted reproductive technology cycle, as well as ovum pick up, increase the possibility of TOA occurrence in them. The use of transvaginal ultrasound guidance drainage approach for the treatment of TOA in selective cases, in addition to broad-spectrum antibiotics in patients might reduce their need for invasive treatment with laparotomy.</p>","PeriodicalId":14386,"journal":{"name":"International Journal of Reproductive Biomedicine","volume":"22 11","pages":"927-934"},"PeriodicalIF":1.6,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of L-carnitine and pentoxifylline on long-term preservation of the human sperms: An experimental study.","authors":"Elham Aliabadi, Zohre Nateghian, Mohammad Hossein Nasr-Esfahani, Marziyeh Tavalaee, Tahereh Talaei-Khozani","doi":"10.18502/ijrm.v22i11.17820","DOIUrl":"10.18502/ijrm.v22i11.17820","url":null,"abstract":"<p><strong>Background: </strong>In infertility clinics, long-time preserving high-quality spermatozoa is a challenging problem.</p><p><strong>Objective: </strong>The present study aimed to prolong preserving of the human spermatozoa by adding pentoxifylline (PT) and L-carnitine (LC) without using high-cost freezing techniques.</p><p><strong>Materials and methods: </strong>In this experimental study, semen samples of 26 normozoospermia men aged between 28-34 yr, were firstly prepared using the swim-up technique, and each sample was divided into the following 3 aliquots: untreated control group, the LC, and PT-treated groups. The samples were stored for up to 12 days at 4-6 C, and sperm motility was assessed. The percentages of the sperms with double-stranded DNA, apoptotic, and acrosomal interacted sperms were evaluated by sperm chromatin structure assay, AnnexinV-PI staining, and peanut agglutinin, respectively.</p><p><strong>Results: </strong>On day 7, 26.83% <math><mo>±</mo></math> 4.26 of sperms were motile in the PT group which was significantly more than LC (6.67% <math><mo>±</mo></math> 0.61) and control (0.83 <math><mo>±</mo></math> 0.17) groups (p <math><mo><</mo></math> 0.001). At day 12, while all sperms lost their motility in LC and control groups, adding PT led to 3.17% <math><mo>±</mo></math> 0.47 sperms remaining motile (p <math><mo><</mo></math> 0.001). Moreover, on day 12, the percent of apoptotic sperms in the PT-treated group (8% <math><mo>±</mo></math> 0.20) was significantly lower than in LC-treated group (5.9% <math><mo>±</mo></math> 0.28, p = 0.03). None of the additives positively affected the number of sperms with double-stranded DNA (p <math><mo>></mo></math> 0.05). LC could also maintain acrosomal integrity over a storage time of up to 12 days.</p><p><strong>Conclusion: </strong>Despite PT's improved sperm motility, LC was more efficient in preventing apoptosis and acrosomal reactions. However, DNA was resistant to denaturation regardless of the treatments.</p>","PeriodicalId":14386,"journal":{"name":"International Journal of Reproductive Biomedicine","volume":"22 11","pages":"871-882"},"PeriodicalIF":1.6,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving reproductive outcomes in frozen embryo transfer over fresh embryo transfer in women with endometrioma: A historical cohort study.","authors":"Parisa Pirooznia, Mehri Mashayekhi, Firouzeh Ghaffari, Nadia Jahangiri, Zahra Zolfaghari, Firoozeh Ahmadi, Fateme Hasani, Nima Narimani","doi":"10.18502/ijrm.v22i11.17819","DOIUrl":"10.18502/ijrm.v22i11.17819","url":null,"abstract":"<p><strong>Background: </strong>Endometrioma, a common manifestation of endometriosis, often indicates the severity of the disease. In vitro fertilization and embryo transfer (ET) are key therapeutic strategies for infertility associated with endometriosis. However, the optimal type of ET (frozen or fresh) and its impact on pregnancy success rates remain debated, with limited studies available.</p><p><strong>Objective: </strong>This historical cohort study aimed to compare fertility and neonatal outcomes, focusing on live birth rate (LBR), clinical pregnancy, and implantation rates in women with endometrioma-associated infertility, between fresh and frozen embryo transfer (FET).</p><p><strong>Materials and methods: </strong>In this historical cohort study, the medical records (files) of 289 women diagnosed with endometrioma-related infertility, who underwent in vitro fertilization/intracytoplasmic sperm injection treatment at Royan Institute, Tehran, Iran between March 2016-2021 were reviewed. Ultimately, 200 files that met the established criteria were selected for review. The extracted data was then compared between groups: FET (n = 121) and fresh ET (n = 79).</p><p><strong>Results: </strong>No significant differences were observed between the groups in terms of demographic characteristics and endometrioma size. The only significant difference in fertility outcomes was the LBR, which was 36.4% for the FET group compared to 22.8% for the fresh ET group (p = 0.04). No significant differences were observed in neonatal outcomes between the groups. Overall, our study suggests that FET may lead to higher LBRs in women diagnosed with endometrioma.</p><p><strong>Conclusion: </strong>Our study suggests that FET may lead to higher LBRs in women diagnosed with endometrioma.</p>","PeriodicalId":14386,"journal":{"name":"International Journal of Reproductive Biomedicine","volume":"22 11","pages":"857-870"},"PeriodicalIF":1.6,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11757671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}