International Journal of Women's Health最新文献

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Flat Magnetic Stimulation for Anal Incontinence: A Prospective Study. 平磁刺激治疗肛门失禁:一项前瞻性研究。
IF 2.5 4区 医学
International Journal of Women's Health Pub Date : 2025-04-21 eCollection Date: 2025-01-01 DOI: 10.2147/IJWH.S512439
Marta Barba, Alice Cola, Ilaria Re, Desirèe De Vicari, Clarissa Costa, Matteo Frigerio, Benedetta Da Pozzo, Serena Maruccia
{"title":"Flat Magnetic Stimulation for Anal Incontinence: A Prospective Study.","authors":"Marta Barba, Alice Cola, Ilaria Re, Desirèe De Vicari, Clarissa Costa, Matteo Frigerio, Benedetta Da Pozzo, Serena Maruccia","doi":"10.2147/IJWH.S512439","DOIUrl":"https://doi.org/10.2147/IJWH.S512439","url":null,"abstract":"<p><strong>Introduction: </strong>Magnetic Stimulation (MS) works on neuromuscular tissue by creating a specific electromagnetic field capable of inducing an intense muscular contraction thereby deeply stimulating pelvic floor muscles and restoring neuromuscular function in a non-invasive manner. Flat MS (FMS) has a more homogeneous electromagnetic field which permits a greater recruitment of muscle fibers. With this study we aimed to evaluate the severity of symptoms and quality of life before and after treatment with Flat Magnetic Stimulation in women with anal incontinence.</p><p><strong>Methods: </strong>This was a prospective observational study conducted from September 2023 to December 2023. At baseline and after the treatment, sexual function and the severity of anal incontinence and were evaluated through validated St. Mark's and the Female Sexual Function Index - 19 (FSFI-19) scores respectively. The subjective improvement rate was determined through the Patient Global Impression of Improvement (PGI-I) questionnaire.</p><p><strong>Results: </strong>We observed that there was a significant improvement in the St.Mark score both absolute and stratified according to the degree of severity, whereas there was no evidence of improvement in sexual function, accessed with the FSFI-19 score.</p><p><strong>Conclusion: </strong>FMS represents an effective and safe non-invasive treatment for anal incontinence, resulting in patients' QOL improvement and decrease of incontinence scores.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1115-1122"},"PeriodicalIF":2.5,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12025822/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143971245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bleeding Through a Pandemic: Women's Lived Experiences with Heavy Menstrual Bleeding During the COVID-19 Pandemic. 大流行期间的出血:COVID-19大流行期间女性大量月经出血的生活经历。
IF 2.5 4区 医学
International Journal of Women's Health Pub Date : 2025-04-18 eCollection Date: 2025-01-01 DOI: 10.2147/IJWH.S476959
Martina Anto-Ocrah, Nabeeha Jabir Affan, Hemika Vempalli, Michael Chen, Celestin Niyomugabo, J Christopher Glantz, Stefanie Hollenbach
{"title":"Bleeding Through a Pandemic: Women's Lived Experiences with Heavy Menstrual Bleeding During the COVID-19 Pandemic.","authors":"Martina Anto-Ocrah, Nabeeha Jabir Affan, Hemika Vempalli, Michael Chen, Celestin Niyomugabo, J Christopher Glantz, Stefanie Hollenbach","doi":"10.2147/IJWH.S476959","DOIUrl":"https://doi.org/10.2147/IJWH.S476959","url":null,"abstract":"<p><strong>Introduction: </strong>Heavy menstrual bleeding (menorrhagia) affects 10 million reproductive-age women. Stress is a mechanism for menstrual disorders, and during the COVID-19 pandemic, women reported worsening premenstrual and menstrual symptoms. We hypothesized that there would be a positive association between COVID stress and menorrhagia and a negative association between menorrhagia and mental health. A third objective was to explore women's lived experiences with menorrhagia during the pandemic, including menstrual pain and impact on socialization, sex life, and product use.</p><p><strong>Methods: </strong>This was a secondary data analyses of a cross-sectional study that recruited adult women between the ages of 18-45 years using Dynata, a survey sampling company that maintains a web panel of survey takers across the United States. Menorrhagia was assessed with the Aberdeen Menorrhagia Severity Scale (AMSS), COVID stress with the COVID-19 Pandemic-related Perceived Stress Scale (PSS-10-C), and mental health with the Mental Health Continuum Scale (MHC-SF). We grouped the participants into mild menorrhagia (AMSS score 0-33)\" and moderate/severe menorrhagia (AMSS score 34-100) and compared the outcomes using descriptive statistics, correlations, and linear regression.</p><p><strong>Results: </strong>The survey was conducted in May 2021. Among 1,037 initial responses, 360 naturally cycling women met the study eligibility criteria. Women with heavy bleeding reported more COVID-stress than those without heavy bleeding (p < 0.01) and heavy bleeding intensified with increasing COVID-related stress (adj. β = 0.37, 95% CI: 0.21, 0.53). Adjusting for baseline depression, mental health worsened as heavy bleeding increased (adj. β = -0.1, 95% CI: -0.24, -0.03). Compared to those without heavy bleeding, women with heavy bleeding were more likely to report severe pain and bed confinement, less socialization, a negative impact on sex life, and greater use of menstrual products.</p><p><strong>Conclusion: </strong>COVID-related stress affects menstrual physiology and also complex interactions between life-course, social functioning, financial strain, and psychological stress. Our findings support increased awareness of these interactions in gynecologic care during a global pandemic.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1083-1101"},"PeriodicalIF":2.5,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013634/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Mobile Health (mHealth) Use by Community Health Workers on the Utilization of Maternity Care in Rural Malawi: A Time Series Analysis [Response to Letter]. 马拉维农村社区卫生工作者使用移动医疗(mHealth)对孕产妇保健利用的影响:时间序列分析[对信函的回应]。
IF 2.5 4区 医学
International Journal of Women's Health Pub Date : 2025-04-17 eCollection Date: 2025-01-01 DOI: 10.2147/IJWH.S528378
Chiyembekezo Kachimanga, Wingston Felix Ng'ambi, Doctor Kazinga, Enoch Ndarama, Mercy Ambogo Amulele, Fabien Munyaneza, Ibukun-Oluwa O Abejirinde, Thomas van den Akker, Alexandra V Kulinkina
{"title":"Impact of Mobile Health (mHealth) Use by Community Health Workers on the Utilization of Maternity Care in Rural Malawi: A Time Series Analysis [Response to Letter].","authors":"Chiyembekezo Kachimanga, Wingston Felix Ng'ambi, Doctor Kazinga, Enoch Ndarama, Mercy Ambogo Amulele, Fabien Munyaneza, Ibukun-Oluwa O Abejirinde, Thomas van den Akker, Alexandra V Kulinkina","doi":"10.2147/IJWH.S528378","DOIUrl":"https://doi.org/10.2147/IJWH.S528378","url":null,"abstract":"","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1067-1068"},"PeriodicalIF":2.5,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12011197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Chain Mediating Effect of Health Literacy and Self-Care Ability on the Relationship Between Dysmenorrhea Symptoms and Negative Emotions Among Chinese Female College Students. 健康素养和自我照顾能力在中国女大学生痛经症状与负性情绪关系中的连锁中介作用
IF 2.5 4区 医学
International Journal of Women's Health Pub Date : 2025-04-16 eCollection Date: 2025-01-01 DOI: 10.2147/IJWH.S511601
Yixin Luo, Dongrun Liu, Guangfan Sun, Yuwen Lu, Mei Fang, Yang Zhang, Caixia Xu, Guifang Bai, Chaoran Chen
{"title":"The Chain Mediating Effect of Health Literacy and Self-Care Ability on the Relationship Between Dysmenorrhea Symptoms and Negative Emotions Among Chinese Female College Students.","authors":"Yixin Luo, Dongrun Liu, Guangfan Sun, Yuwen Lu, Mei Fang, Yang Zhang, Caixia Xu, Guifang Bai, Chaoran Chen","doi":"10.2147/IJWH.S511601","DOIUrl":"https://doi.org/10.2147/IJWH.S511601","url":null,"abstract":"<p><strong>Background: </strong>Dysmenorrhea, a common concern among female college students, is closely linked to anxiety and depression, particularly during the early menstrual phase (the first one to two days of menstruation), when cramping pain in the lower abdomen and other discomforts occur. This study aims to assess the current status of dysmenorrhea and negative emotions among female college students and explore the factors influencing the relationship between menstrual pain and negative emotions.</p><p><strong>Methods: </strong>A total of 1,117 female college students with moderate to severe dysmenorrhea (based on a Visual Analog Scale (VAS) ≥ 4) were recruited from five universities in Guangdong Province through purposive and convenience sampling to complete an online survey between August and October 2024. Data were collected using multiple standardized scales. Pearson correlation coefficients were used to examine the relationships between variables. Multiple linear regression analysis was conducted to analyze the effects of variables with statistically significant differences (P < 0.05) identified through one-way ANOVA, independent sample t-tests, and correlation analysis on psychological levels. Structural Equation Modeling (SEM) was used to explore mediating effects.</p><p><strong>Results: </strong>This study shows that dysmenorrhea symptoms, health literacy, self-care ability, and negative emotions are significantly correlated. Health literacy and self-care ability play a chain mediating role between dysmenorrhea symptoms and negative emotions, with a mediating effect of 0.026, accounting for 4.87% of the total effect.</p><p><strong>Conclusion: </strong>The findings suggests that health literacy and self-care ability play a chain-mediating role between dysmenorrhea symptoms and negative emotions. It provides new insights for intervening in emotional issues related to dysmenorrhea in female college students. Universities and healthcare institutions should focus on enhancing health literacy and self-care abilities among female college students, offering effective health education and resources to help them better manage menstrual pain and reduce anxiety and depression.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1069-1082"},"PeriodicalIF":2.5,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12009575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lipidomics Reveals Common Mechanisms in Polycystic Ovarian Syndrome, Recurrent Spontaneous Abortion, and Infertility: A Genetic-Based Analysis. 脂质组学揭示了多囊卵巢综合征、复发性自然流产和不孕症的共同机制:一项基于遗传的分析。
IF 2.5 4区 医学
International Journal of Women's Health Pub Date : 2025-04-13 eCollection Date: 2025-01-01 DOI: 10.2147/IJWH.S514221
Ailin Tao, Tianqiang Wu, Xinyu Han, Dingren Niu, Xiaoling Feng
{"title":"Lipidomics Reveals Common Mechanisms in Polycystic Ovarian Syndrome, Recurrent Spontaneous Abortion, and Infertility: A Genetic-Based Analysis.","authors":"Ailin Tao, Tianqiang Wu, Xinyu Han, Dingren Niu, Xiaoling Feng","doi":"10.2147/IJWH.S514221","DOIUrl":"https://doi.org/10.2147/IJWH.S514221","url":null,"abstract":"<p><strong>Background: </strong>Polycystic ovary syndrome (PCOS), infertility, and recurrent spontaneous abortion (RSA) pose significant challenges to women's reproductive health. While dyslipidemia plays a critical role in these conditions, the causal relationships between specific lipids and these pathologies, as well as their shared mechanisms, remain unclear.</p><p><strong>Methods: </strong>We conducted genome-wide association studies (GWAS) to identify genetic variants associated with 179 plasma lipid species and obtained outcome data for PCOS, infertility, and RSA from the FinnGen R10 database. Mendelian randomization (MR) was performed with genetic variants as instrumental variables (IVs) to assess causal relationships. The inverse variance weighted (IVW) method was the primary approach in our two-sample MR study. Robustness was validated through assessments of heterogeneity, pleiotropy, and leave-one-out analyses.</p><p><strong>Results: </strong>IVW analysis identified 17 plasma lipid species significantly associated with PCOS risk (P < 0.05), including sphingomyelin (d38:2) (OR = 0.909, 95% CI: 0.835-0.990, P = 0.0277) and triacylglycerol (48:2) (OR = 1.291, 95% CI: 1.097-1.518, P = 0.0020). Similarly, 15 lipid species were significantly associated with infertility risk (P < 0.05), such as sphingomyelin (d36:2) (OR = 0.926, 95% CI: 0.888-0.966, P = 0.0003) and triacylglycerol (48:2) (OR = 1.122, 95% CI: 1.059-1.188, P < 0.0001). Two lipid species, phosphatidylinositol (18:0_20:4) (OR = 0.790, 95% CI: 0.693-0.900, P = 0.0004) and sphingomyelin (d42:2) (OR = 0.779, 95% CI: 0.672-0.903, P = 0.0009), showed significant inverse associations with RSA risk, suggesting protective effects.</p><p><strong>Conclusion: </strong>This study establishes causal relationships between specific lipid species and the risk of PCOS, infertility, and RSA, emphasizing lipid metabolism dysregulation as a common pathological mechanism underlying these reproductive disorders. Targeting lipids may offer a promising therapeutic strategy for these diseases.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1055-1065"},"PeriodicalIF":2.5,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12005215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Three Separate Cases of Polypoid Endometriosis Coincided with Abscess, Angioleiomyoma or Stromal Sarcoma. 息肉样子宫内膜异位症合并脓肿、血管平滑肌瘤或间质肉瘤3例。
IF 2.5 4区 医学
International Journal of Women's Health Pub Date : 2025-04-13 eCollection Date: 2025-01-01 DOI: 10.2147/IJWH.S508521
Zaigui Wu, Qiong Xu, Yao Sun, Fei Ruan
{"title":"Three Separate Cases of Polypoid Endometriosis Coincided with Abscess, Angioleiomyoma or Stromal Sarcoma.","authors":"Zaigui Wu, Qiong Xu, Yao Sun, Fei Ruan","doi":"10.2147/IJWH.S508521","DOIUrl":"https://doi.org/10.2147/IJWH.S508521","url":null,"abstract":"<p><strong>Background: </strong>Polypoid endometriosis is rare and differs from classic endometriosis. It has been primarily documented in case reports and often misdiagnosed as malignancy. The aim of this study is to report three separate cases of polypoid endometriosis coincided with multiple abscess, angioleiomyoma or stromal sarcoma, respectively.</p><p><strong>Case presentation: </strong>The first case was 36 years old and presented with six months of dysmenorrhea and menstrual fever. Two cervical masses, one located in vaginal and one in pelvic, were detected by ultrasound. After a total hysterectomy, she was diagnosed with cervical polypoid endometriosis with multiple abscess. The second case aged 36-years too and had menstrual bleeding prolonged to 10-15 days for four months. Ultrasound showed a 6cm mass like leiomyomas but with rich vascularity, while MRI tested signal intensity similar to that of endometrium. A diagnosis of polypoid endometriosis coincided with angioleiomyoma was made after surgery. The third patient was 40 and experienced lower abdominal pain for eight months. The ultrasound and MRI tested multiple solid-cystic masses in the left ovary and pelvic. The subsequent pathology revealed extensive stromal nodules in various areas such as bilateral ovaries, posterior uterine wall, intestinal tract and left ureter, indicating the diagnosis of low malignant potential stromal sarcoma.</p><p><strong>Conclusion: </strong>Polypoid endometriosis coincided with multiple abscess, angioleiomyoma or stromal sarcoma are rather rare and require aggressive surgical treatment.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1049-1054"},"PeriodicalIF":2.5,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11998930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143980557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bidirectional Two-Sample Mendelian Randomization Study Reveals Causal Associations Between Aging and Endometriosis. 双向双样本孟德尔随机研究揭示了衰老与子宫内膜异位症之间的因果关系。
IF 2.5 4区 医学
International Journal of Women's Health Pub Date : 2025-04-13 eCollection Date: 2025-01-01 DOI: 10.2147/IJWH.S504181
Limei Chen, Han Yan, Jichan Nie
{"title":"Bidirectional Two-Sample Mendelian Randomization Study Reveals Causal Associations Between Aging and Endometriosis.","authors":"Limei Chen, Han Yan, Jichan Nie","doi":"10.2147/IJWH.S504181","DOIUrl":"https://doi.org/10.2147/IJWH.S504181","url":null,"abstract":"<p><strong>Background: </strong>Previous studies have suggested that aging may influence reproductive functions of female. Nonetheless, the causal relationship between aging and endometriosis has yet to be completely understood.</p><p><strong>Objective: </strong>This study aims to determine whether aging had a causal association with the incidence of endometriosis.</p><p><strong>Methods: </strong>We conducted bidirectional MR analyses to evaluate the causal relationship between aging biomarkers, particularly leukocyte telomere length (LTL), and endometriosis risk. Instrumental variables for LTL were derived from the UK Biobank GWAS, while endometriosis-associated variants were obtained from the FinnGen GWAS dataset. Subgroup analyses were performed to investigate the association between LTL and endometriosis subtypes. Additionally, validation was performed using independent GWAS meta-analysis datasets.</p><p><strong>Results: </strong>Inverse variance-weighted (IVW) analysis revealed a significant association between longer LTL and an increased risk of endometriosis (OR-IVW = 1.276, 95% CI: 1.143 to 1.424, FDR-adjusted <i>P</i> = 7.00E-5), with consistent findings across multiple MR methods. Sensitivity analysis using an independent GWAS meta-analysis dataset did not confirm the LTL-endometriosis association (OR-IVW = 1.128, 95% CI: 0.140 to 9.115, <i>P</i> = 0.910). Bidirectional MR analysis found no causal relationship between endometriosis and LTL. Subgroup analyses indicated that longer LTL was significantly associated with endometriosis of the ovary (OR-IVW = 1.343, 95% CI: 1.143 to 1.577, <i>P</i> = 3.00E-4) and endometriosis of the rectovaginal septum and vagina (OR-IVW = 1.336, 95% CI: 1.064 to 1.676, <i>P</i> = 0.013), while no significant association was found with endometriosis of the pelvic peritoneum.</p><p><strong>Conclusion: </strong>Our findings suggest that longer LTL may contribute to an increased risk of endometriosis, particularly in ovarian and rectovaginal subtypes. However, no causal effect of endometriosis on aging was observed. The lack of replication in independent datasets highlights the potential influence of population heterogeneity and dataset-specific factors, warranting further validation in diverse cohorts.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1027-1037"},"PeriodicalIF":2.5,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12005205/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143994958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between Dietary Taste Preferences and Primary Ovarian Insufficiency: A Mendelian Randomization Study. 饮食口味偏好与原发性卵巢功能不全之间的关系:一项孟德尔随机研究。
IF 2.5 4区 医学
International Journal of Women's Health Pub Date : 2025-04-13 eCollection Date: 2025-01-01 DOI: 10.2147/IJWH.S505332
Shuying Xu, You Zhou, Lina Wang, Yang Zhang
{"title":"Association Between Dietary Taste Preferences and Primary Ovarian Insufficiency: A Mendelian Randomization Study.","authors":"Shuying Xu, You Zhou, Lina Wang, Yang Zhang","doi":"10.2147/IJWH.S505332","DOIUrl":"https://doi.org/10.2147/IJWH.S505332","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the effects of dietary taste preferences on primary ovarian insufficiency (POI) by two-sample Mendelian randomization analysis, excluding confounding factors.</p><p><strong>Patients and methods: </strong>Single nucleotide polymorphisms (SNPs) associated with 139 dietary taste preferences were obtained from GWAS results provided by May-Wilson S et al. Data for POI were obtained from the FinnGen Biobank. The relationship between dietary taste preferences and POIs was explored using IVW as the primary method. The MR-Egger intercept term test and Cochran's Q test examined sensitivity, multiplicity, and heterogeneity. The analyses were visualized by plotting scatterplots, funnel plots, and leave-one-out plots.</p><p><strong>Results: </strong>IVW analysis showed that preference for sweet food (p=0.034), preference for cake (p=0.040), preference for white wine (p=0.048) was positively associated with the risk of developing POI, preference for bitter food (p=0.048), preference for Mackerel (p=0.031), preference for Gherkins (p=0.024), preference for Cream (p= 0.009) and preference for Soya milk (p=0.042) were negatively associated with the risk of developing POI, while there was no significant association between preference for salty food (p=0.350) and preference for spicy food (p=0.827) and POI.</p><p><strong>Conclusion: </strong>This study suggests that food preference is a heritable trait, that food preference is the primary reason people choose their food intake, and that alterations in taste-related receptor genes may affect ovarian function. These findings could help guide improved dietary guidelines and thus control the progression of POI.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1039-1047"},"PeriodicalIF":2.5,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12005201/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Influence of Subclinical Hypothyroidism on Endocrine and Metabolic Characteristics in Patients with Polycystic Ovary Syndrome. 亚临床甲状腺功能减退症对多囊卵巢综合征患者内分泌及代谢特征的影响。
IF 2.5 4区 医学
International Journal of Women's Health Pub Date : 2025-04-10 eCollection Date: 2025-01-01 DOI: 10.2147/IJWH.S517997
Fang Dai, Zijian Wu, Shuai Qin, Fang Wu, Mingqiang Wang, Xiangxiu Liu, Fen Liu
{"title":"The Influence of Subclinical Hypothyroidism on Endocrine and Metabolic Characteristics in Patients with Polycystic Ovary Syndrome.","authors":"Fang Dai, Zijian Wu, Shuai Qin, Fang Wu, Mingqiang Wang, Xiangxiu Liu, Fen Liu","doi":"10.2147/IJWH.S517997","DOIUrl":"https://doi.org/10.2147/IJWH.S517997","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the influence of subclinical hypothyroidism (SCH) on endocrine and metabolic characteristics in patients with polycystic ovary syndrome (PCOS).</p><p><strong>Methods: </strong>A total of 198 cases of PCOS patients admitted to our hospital from January 2022 to December 2023 were selected for the study. According to the presence or absence of SCH, patients were divided into the SCH group (n = 40) and the non-SCH group (n = 158). Differences in demographic characteristics, thyroid hormones, sex hormones, and glucose and lipid metabolism were analyzed between the two groups. Additionally, the correlation between SCH and various endocrine and metabolic indicators in PCOS patients was assessed.</p><p><strong>Results: </strong>There was no statistically significant difference in demographic characteristics between the two groups (<i>P</i> > 0.05). Compared to the non-SCH group, the SCH group had significantly higher levels of serum luteinizing hormone (LH), prolactin (PRL), triglycerides (TG), total cholesterol (TC), fasting insulin (FINS), and homeostasis model assessment of insulin resistance (HOMA-IR) (<i>P</i> < 0.05), Conversely, the SCH group had significantly lower levels of serum follicle-stimulating hormone (FSH), estradiol (E2), thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), and free thyroxine (FT4) (<i>P</i> < 0.05). Correlation analysis indicated that LH, FSH, E2, PRL, TSH, TG, TC, FINS, HOMA-IR were positively correlated with PCOS complicated by SCH, while FT3, FT4 were negatively correlated.</p><p><strong>Conclusion: </strong>SCH in PCOS patients is associated with endocrine and metabolic dysfunction, primarily affecting thyroid hormone levels, sex hormones, and glucose and lipid metabolism. Assessing thyroid function is essential for the comprehensive evaluation and management of PCOS patients.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1019-1026"},"PeriodicalIF":2.5,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11995925/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Efficacy of Abdominal Aortic ABO (AABO) vs Common Iliac Artery ABO (CIABO) in Cesarean Delivery for Central Placenta Previa with Placenta Accreta: A Retrospective Study. 腹主动脉ABO (AABO)与髂总动脉ABO (CIABO)在中央前置胎盘伴增生胎盘剖宫产中的比较疗效:回顾性研究。
IF 2.5 4区 医学
International Journal of Women's Health Pub Date : 2025-04-09 eCollection Date: 2025-01-01 DOI: 10.2147/IJWH.S512150
Yumei Cao, Yunxia Zhao, Jianlei Ren, Lan Ma, Zhenlan Wu, Qingliang Lv
{"title":"Comparative Efficacy of Abdominal Aortic ABO (AABO) vs Common Iliac Artery ABO (CIABO) in Cesarean Delivery for Central Placenta Previa with Placenta Accreta: A Retrospective Study.","authors":"Yumei Cao, Yunxia Zhao, Jianlei Ren, Lan Ma, Zhenlan Wu, Qingliang Lv","doi":"10.2147/IJWH.S512150","DOIUrl":"https://doi.org/10.2147/IJWH.S512150","url":null,"abstract":"<p><strong>Objective: </strong>To compare the safety and efficacy of abdominal aortic balloon occlusion (AABO) and common iliac artery balloon occlusion (CIABO) in cesarean deliveries for central placenta previa with placenta accreta, using a retrospective study design.</p><p><strong>Methods: </strong>We retrospectively analyzed 65 patients with central placenta previa and placenta accreta who underwent cesarean delivery at our hospital between January 2020 and April 2024. Patients were divided into two groups: the observation group (n=35) received AABO, while the control group (n=30) received CIABO. Outcomes compared included intraoperative blood loss, maternal and neonatal outcomes, and other relevant factors. Data were analyzed using SPSS 26.0, with normally distributed quantitative data assessed by <i>t</i>-tests and categorical data by chi-square tests. A p-value <0.05 was considered significant.</p><p><strong>Results: </strong>The AABO group had significantly reduced balloon placement time, radiation exposure, intraoperative blood loss (mean 800 ± 150 mL vs 1200 ± 180 mL in CIABO; p<0.05), and transfusion volume (mean 400 ± 100 mL vs 600 ± 120 mL in CIABO; p<0.05). The hysterectomy rate was lower in the AABO group (5.7% vs 16.7% in CIABO; p<0.05). No significant differences were observed in postpartum hemorrhage (14.3% vs 13.3%; p>0.05) or neonatal asphyxia (2.9% vs 3.3%; p>0.05). Postoperative coagulation function at 24 hours was better in the AABO group (p<0.05), with no significant difference in postoperative complications (p>0.05).</p><p><strong>Conclusion: </strong>AABO in cesarean deliveries for central placenta previa with placenta accreta reduces intraoperative blood loss and hysterectomy rates without adverse fetal effects, making it a valuable clinical option.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1001-1008"},"PeriodicalIF":2.5,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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