International Journal of Women's Health最新文献

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Risk Factors for Postpartum Hemorrhage Following Vaginal Deliveries in China: A Case-Control Study of Second Births After IUD Removal. 中国阴道分娩后产后出血的危险因素:摘除宫内节育器后二胎的病例对照研究
IF 2.5 4区 医学
International Journal of Women's Health Pub Date : 2025-05-01 eCollection Date: 2025-01-01 DOI: 10.2147/IJWH.S516263
Liping Shen, Yang Xu, Baoxia Li, Yuyun Long
{"title":"Risk Factors for Postpartum Hemorrhage Following Vaginal Deliveries in China: A Case-Control Study of Second Births After IUD Removal.","authors":"Liping Shen, Yang Xu, Baoxia Li, Yuyun Long","doi":"10.2147/IJWH.S516263","DOIUrl":"https://doi.org/10.2147/IJWH.S516263","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to evaluate the predictive value of risk factors for postpartum hemorrhage (PPH) following vaginal delivery, with a special focus on the impact of intrauterine device (IUD) usage in the context of recent policy changes allowing more childbirths in China.</p><p><strong>Methods: </strong>A total of 6879 women who underwent vaginal deliveries from January 2021 to December 2023 in the Lianyungang regional maternal care system and met the inclusion and exclusion criteria were enrolled. A case-control design was employed, comprising 524 women with PPH (blood loss ≥500 mL) 24h after giving birth and an equal number of controls (blood loss <500 mL) matched on a 1:1 ratio. Univariate and multivariate logistic regression analyses, alongside ROC curve analysis, were conducted to identify risk factors for PPH.</p><p><strong>Results: </strong>Univariate analysis revealed significant differences in age (OR = 1.86, 95% CI: 1.35-2.57, P < 0.01), number of miscarriages (OR = 1.97, 95% CI: 1.46-2.65, P < 0.001), gestational week, number of fetuses, weight of the second child (OR = 10.78, 95% CI: 7.88-14.75, P < 0.001), placental adhesion, and uterine atony (OR = 2.40, 95% CI: 1.60-3.61, P < 0.001). No significant differences were observed regarding occupation, educational level, mode of first delivery, IUD use and duration, and presence of gestational diabetes or hypertension (P > 0.05). Multivariate logistic regression identified age, number of miscarriages, weight of the second child, and uterine atony as independent risk factors for PPH (P < 0.05). ROC curve analysis showed that the combined predictive value of these factors was superior, with an AUC of 0.805 for the combined predictive model.</p><p><strong>Conclusion: </strong>PPH is influenced by advanced maternal age, multiple miscarriages, high birth weight, and uterine atony. IUD use may not independently impact the likelihood of PPH under the conditions studied.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1203-1214"},"PeriodicalIF":2.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12053772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systemic Inflammatory Biomarkers as a Predictive Markers for Ovarian Cancer. 系统性炎症生物标志物作为卵巢癌的预测标志物。
IF 2.5 4区 医学
International Journal of Women's Health Pub Date : 2025-04-30 eCollection Date: 2025-01-01 DOI: 10.2147/IJWH.S496137
Andi Kurniadi, Steven Ridwan, Yudi Mulyana Hidayat, Syahrul Rauf, Kemala Isnainiasih Mantilidewi, Gatot N A Winarno, Siti Salima, Dodi Suardi
{"title":"Systemic Inflammatory Biomarkers as a Predictive Markers for Ovarian Cancer.","authors":"Andi Kurniadi, Steven Ridwan, Yudi Mulyana Hidayat, Syahrul Rauf, Kemala Isnainiasih Mantilidewi, Gatot N A Winarno, Siti Salima, Dodi Suardi","doi":"10.2147/IJWH.S496137","DOIUrl":"https://doi.org/10.2147/IJWH.S496137","url":null,"abstract":"<p><strong>Objective: </strong>Tumor markers such as CA125 are highly beneficial in predictive ovarian malignancy; however, this advanced test is not always available in remote areas. To address this issue, the author aimed to explore the use of systemic inflammatory biomarkers as complementary modalities for diagnosis of ovarian malignancy.</p><p><strong>Methods: </strong>This diagnostic study utilized a cross-sectional approach, with outcomes measured by AUC and sensitivity. A total of 132 patients with adnexal tumors were consecutively included and measured a complete blood count. From this, the MLR (Monocyte Lymphocyte Ratio), NLR (Neutrophil Lymphocyte Ratio), PLR (Platelet Lymphocyte Ratio), SII (Systemic Immune Inflammation Index), and SIRI (Systemic Inflammatory Response Index) biomarkers were calculated. After surgery, histopathological examination was performed as the gold standard and the biomarker predictions were then compared to it, followed by statistical analysis.</p><p><strong>Results: </strong>The AUC values for MLR, NLR, PLR, SII, and SIRI were 0.70, 0.731, 0.696, 0.743, and 0.722, respectively. The p-values were MLR (0.005), NLR (0.001), PLR (0.001), SII (<0.001), and SIRI (<0.001), respectively. In multivariate analysis, only SII was significant (p = 0.015). The Exp(B) and 95% CI were 5.472 (1.383-21.655). The validity test for SII showed satisfactory results: sensitivity 71.64%, specificity 73.84%, PPV 73.84%, NPV 71.64%, accuracy 72.72%, LR+ 2.74%, and LR- 0.38%.</p><p><strong>Conclusion: </strong>Systemic inflammatory biomarkers, particularly SII may aid in the predictive markers of early ovarian with diagnostic values nearly as good as CA125 (sensitivity 71.64% vs 75.97%). These biomarkers can serve as complementary predictive markes modalities for ovarian malignancy, especially when advanced tumor marker tests like CA125 are not available in remote areas.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1193-1201"},"PeriodicalIF":2.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12050043/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143997393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determinants of Successful Vaginal Birth After Cesarean Section: A Retrospective Cohort Study in Southeast China. 剖宫产后阴道分娩成功的决定因素:中国东南部回顾性队列研究。
IF 2.5 4区 医学
International Journal of Women's Health Pub Date : 2025-04-30 eCollection Date: 2025-01-01 DOI: 10.2147/IJWH.S507648
Ying-Ling Xiu, Bing-Qing Lv
{"title":"Determinants of Successful Vaginal Birth After Cesarean Section: A Retrospective Cohort Study in Southeast China.","authors":"Ying-Ling Xiu, Bing-Qing Lv","doi":"10.2147/IJWH.S507648","DOIUrl":"https://doi.org/10.2147/IJWH.S507648","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to identify factors influencing the success of a trial of labor after cesarean section (TOLAC) and to evaluate associated maternal and neonatal outcomes.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on data from women with a prior cesarean section who underwent TOLAC at Fujian Maternity and Child Health Hospital in Southeast China between January 2016 and January 2018. Of the 1179 women who attempted TOLAC, 1038 achieved vaginal birth after cesarean (VBAC) while 141 experienced unsuccessful trials. Sociodemographic and clinical characteristics were compared between the successful and unsuccessful TOLAC groups using the <i>t</i>-test for normally distributed data, non-parametric tests for non-normally distributed data, and the χ2 test, corrected chi-square test, or Fisher's exact test for categorical variables, as appropriate. Logistic regression analysis was performed to identify factors independently associated with successful TOLAC, with the results expressed as Odds Ratios (ORs) and corresponding 95% Confidence Intervals (CIs).</p><p><strong>Results: </strong>Multivariable logistic regression analysis revealed that maternal height (OR = 1.09, 95% CI = 1.05-1.14), abdominal circumference (OR = 0.95, 95% CI = 0.91-0.98), ultrasound-estimated fetal weight (OR = 0.99, 95% CI = 0.99-1.00), and history of vaginal delivery (OR = 9.62, 95% CI = 2.33-39.67) were independently associated with successful TOLAC. No significant differences were observed between the successful and unsuccessful TOLAC groups in terms of neonatal asphyxia, postpartum hemorrhage, placental abruption, or bladder injury.</p><p><strong>Conclusion: </strong>Maternal height, abdominal circumference, ultrasound-estimated fetal weight, and history of vaginal delivery were identified as influential factors for VBAC success. Clinical evaluation of these factors may enhance the selection criteria for TOLAC candidates, potentially increasing VBAC rates and reducing cesarean section rates overall.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1183-1191"},"PeriodicalIF":2.5,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12050019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare Case Report: Coexistence of Complete Hydatidiform Mole and Normal Fetus in a Twin Pregnancy. 罕见病例报告:完全葡萄胎和正常胎儿共存的双胎妊娠。
IF 2.5 4区 医学
International Journal of Women's Health Pub Date : 2025-04-28 eCollection Date: 2025-01-01 DOI: 10.2147/IJWH.S510609
Ping Li, XiuPing Liu
{"title":"Rare Case Report: Coexistence of Complete Hydatidiform Mole and Normal Fetus in a Twin Pregnancy.","authors":"Ping Li, XiuPing Liu","doi":"10.2147/IJWH.S510609","DOIUrl":"https://doi.org/10.2147/IJWH.S510609","url":null,"abstract":"<p><strong>Background: </strong>The coexistence of a complete hydatidiform mole with a normal fetus in a twin pregnancy is a rare, high-risk obstetric condition with an extremely low incidence rate, presenting numerous clinical management challenges. The rarity of such cases, coupled with the scarcity of comprehensive literature, makes the successful management of this case a source of valuable experience and novel insights for clinical practice.</p><p><strong>Case presentation: </strong>A 32-year-old patient conceived following a clomiphene-induced ovulation regimen. Mid-pregnancy ultrasound indicated a twin pregnancy (one viable fetus, the other consistent with the appearance of a complete hydatidiform mole), and the patient chose to continue the pregnancy. At 36+4 weeks of gestation, the patient was admitted for pregnancy-induced hypertension and underwent a cesarean section, delivering a healthy female infant and simultaneously removing the molar tissue. Postoperative pathological examination confirmed a complete hydatidiform mole with invasive lesions, which progressed to an invasive hydatidiform mole. The patient underwent seven cycles of methotrexate combination chemotherapy, with a follow-up period of three years showing no recurrence, ensuring the health of both mother and child.</p><p><strong>Conclusion: </strong>Managing twin gestations involving a complete hydatidiform mole and a normal fetus necessitates a multidisciplinary approach, grounded in individualized assessment. The successful treatment of this case demonstrates that standardized diagnosis, close postoperative follow-up, and chemotherapy are crucial factors in improving maternal and fetal outcomes, offering significant clinical reference value.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1175-1181"},"PeriodicalIF":2.5,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12047649/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MiR-484 Regulates the IL-6/STAT3 Signaling Pathway by Down-Regulating KLF12 to Inhibit the Malignant Progression of Cervical Cancer. MiR-484通过下调KLF12调控IL-6/STAT3信号通路抑制宫颈癌恶性进展
IF 2.5 4区 医学
International Journal of Women's Health Pub Date : 2025-04-26 eCollection Date: 2025-01-01 DOI: 10.2147/IJWH.S491749
Keyong Bao, Xue Zhang, Lihong Bao, Xiaoyu Tao, Li Zhang, Dong Wang
{"title":"MiR-484 Regulates the IL-6/STAT3 Signaling Pathway by Down-Regulating KLF12 to Inhibit the Malignant Progression of Cervical Cancer.","authors":"Keyong Bao, Xue Zhang, Lihong Bao, Xiaoyu Tao, Li Zhang, Dong Wang","doi":"10.2147/IJWH.S491749","DOIUrl":"https://doi.org/10.2147/IJWH.S491749","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to investigate the function of miR-484 in C33A cells, as well as its mechanism.</p><p><strong>Methods: </strong>The mRNA expression patterns of miR-484 and Krüppel-like factor 12 (KLF12) in C33A cells were detected by quantitative reverse transcription polymerase chain reaction. MiR-484 mimics and miR-484 negative controls were transfected into C33A cells. Luciferase reporter assay was used to confirm the binding of miR-484 and KLF12. The effects of miR-484 on cell viability, migration, invasion, and apoptosis were assessed using the cell counting kit-8 assay, wound healing assay, Transwell assay, flow cytometry, and Western blot. Rescue experiments were performed by overexpressing KLF12. Western blot was utilized to examine the expression of KLF12, interleukin-6 (IL-6), Janus Kinase 2, phosphorylated-Janus Kinase 2, signal transducer and activator of transcription 3 (STAT3), and phosphorylated-STAT3 proteins.</p><p><strong>Results: </strong>MiR-484 expression was down-regulated in C33A cells, while KLF12 was up-regulated. The luciferase reporter assay confirmed the direct binding of miR-484 to KLF12. MiR-484 inhibited the proliferation, migration, and invasion of C33A cells while promoting apoptosis. Additionally, it could inhibit the expression of KLF12 protein and the activation of the IL-6/STAT3 signaling pathway. However, KLF12 overexpression could reverse the above effects.</p><p><strong>Conclusion: </strong>MiR-484 can specifically inhibit the KLF12-mediated IL-6/STAT3 signaling pathway, thereby suppressing the malignant biological behavior of C33A cells.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1165-1174"},"PeriodicalIF":2.5,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12042840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of Acupuncture for Diminished Ovarian Reserve: A Randomized Controlled Trial Protocol. 针灸治疗卵巢储备功能减退的疗效:一项随机对照试验方案。
IF 2.5 4区 医学
International Journal of Women's Health Pub Date : 2025-04-23 eCollection Date: 2025-01-01 DOI: 10.2147/IJWH.S499417
Yuemeng Zhao, Liying Liu, Xinyue Tao, Di Gan, Yuanyuan Lai, Chunhui Tian, Lei Huang, Yufei Huang, Jie Yang
{"title":"Efficacy of Acupuncture for Diminished Ovarian Reserve: A Randomized Controlled Trial Protocol.","authors":"Yuemeng Zhao, Liying Liu, Xinyue Tao, Di Gan, Yuanyuan Lai, Chunhui Tian, Lei Huang, Yufei Huang, Jie Yang","doi":"10.2147/IJWH.S499417","DOIUrl":"https://doi.org/10.2147/IJWH.S499417","url":null,"abstract":"<p><strong>Background: </strong>With diminished ovarian reserve (DOR) becoming increasingly younger in women, age-related fertility decline in females is gradually becoming one of the most important factors affecting female fertility. The purpose of the study is to assess whether acupuncture can successfully relieve the age-related decline in female fertility. This will provide substantial proof in support of the therapeutic effectiveness of acupuncture.</p><p><strong>Methods: </strong>This is a randomized, double-blind, controlled trial. There will be 108 participants diagnosed with DOR recruited in China. Participants will be randomly assigned in a 1:1 ratio to two groups, including acupuncture and sham acupuncture groups. The participants will receive acupuncture treatments three times a week, each lasting 30 minutes, for 36 weeks. The primary outcome was the change in ovarian function modeling as assessed by four metrics: age, ovarian reserve markers such as follicle-stimulating hormone (FSH) and anti-Müllerian hormone (AMH) in the Ovarian Reserve Function Prediction Tool (OvaRePred). Secondary outcomes will include changes in the antral follicle count (AFC), serum sex hormone levels, Zung's Self-rating Anxiety Scale (SAS), and the Self-rating Depression Scale (SDS). Adverse events (AEs) associated with acupuncture will be documented following each treatment session. AEs will be monitored and reported to ensure patient safety throughout the trial.</p><p><strong>Expected results and conclusion: </strong>We will be able to measure the effectiveness of acupuncture for patients with DOR and whether acupuncture is superior to sham acupuncture. The proposed acupuncture treatment might provide an alternative option for those patients.</p><p><strong>Trial registration number: </strong>ChiCTR2400086376.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1131-1141"},"PeriodicalIF":2.5,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12034248/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143990143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case Report of Successful Vaginal Delivery for Cauda Equina Syndrome Combined with Complex Regional Pain Syndrome. 马尾综合征合并复杂局部疼痛综合征阴道分娩成功1例报告。
IF 2.5 4区 医学
International Journal of Women's Health Pub Date : 2025-04-23 eCollection Date: 2025-01-01 DOI: 10.2147/IJWH.S518171
Hwawon Lim, Yumi Shin, Hyunjo Kim, Bo Young Choi, Jee Yoon Park, Jae-Young Lim, Pyung-Bok Lee
{"title":"A Case Report of Successful Vaginal Delivery for Cauda Equina Syndrome Combined with Complex Regional Pain Syndrome.","authors":"Hwawon Lim, Yumi Shin, Hyunjo Kim, Bo Young Choi, Jee Yoon Park, Jae-Young Lim, Pyung-Bok Lee","doi":"10.2147/IJWH.S518171","DOIUrl":"https://doi.org/10.2147/IJWH.S518171","url":null,"abstract":"<p><strong>Background: </strong>Cauda equina syndrome (CES) is defined as a complex clinical entity associated with simultaneous compression of several or all lumbosacral spine nerve roots. Complex regional pain syndrome (CRPS) is a chronic and non-treatable pain condition resulting in lifetime disability due to a tendency to relapse. Both diseases present with chronic pain and neuropathy. We aimed to report a unique patient with successful pregnancy and delivery although she had both CES and CRPS.</p><p><strong>Case presentation: </strong>Here we present a female who was diagnosed as CES with CRPS after fall from a high building about 10 years previously. She became pregnant after two miscarriages, maintained her pregnancy with numerous pain killers and finally delivered a healthy baby vaginally. Interestingly, during her parturition, she was tolerable with labor pain unlike her chronic pain that came from CES and CRPS.</p><p><strong>Conclusion: </strong>She is a unique and significant case because of the rare condition that has two pain-associated diseased and success of vaginal delivery without any complication during pregnancy. This case may be helpful in counselling attending physicians and may inspire other pre-existing CES or CRPS patients who are afraid to decide on pregnancy.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1123-1129"},"PeriodicalIF":2.5,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12034279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143969872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the Recurrence Risk Factors and Development of a Nomogram Prediction Model for Uterine Fibroid Patients Post-Myomectomy Based on Patient Medical Records. 基于病历的子宫肌瘤切除术后复发危险因素探讨及Nomogram预测模型的建立
IF 2.5 4区 医学
International Journal of Women's Health Pub Date : 2025-04-23 eCollection Date: 2025-01-01 DOI: 10.2147/IJWH.S515545
Caixia Li, Liumin Li, Yingchun Hu
{"title":"Exploring the Recurrence Risk Factors and Development of a Nomogram Prediction Model for Uterine Fibroid Patients Post-Myomectomy Based on Patient Medical Records.","authors":"Caixia Li, Liumin Li, Yingchun Hu","doi":"10.2147/IJWH.S515545","DOIUrl":"https://doi.org/10.2147/IJWH.S515545","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to investigate the risk factors contributing to the recurrence of uterine fibroids in patients undergoing laparoscopic myomectomy, providing a basis for clinical treatment.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 378 patients who underwent laparoscopic myomectomy between January 2022 and August 2023 and were subsequently followed up. Based on the recurrence status 6 months post-operation, patients were divided into a recurrence group (43 cases) and a non-recurrence group (335 cases). Clinical data of both groups were analyzed using univariate analysis, and factors statistically significant in univariate analysis were further evaluated through multivariate logistic regression to identify independent risk factors for recurrence post-laparoscopic myomectomy.</p><p><strong>Results: </strong>Univariate analysis indicated that the proportion of patients with ≥2 fibroids, intramural fibroids, and preoperative serum C-reactive protein (CRP) levels ≥4.67 mg/L was significantly higher in the recurrence group (all P<0.05). Multivariate logistic regression analysis revealed that having ≥2 fibroids, a uterine size ≥14 gestational weeks, intramural fibroids, and preoperative serum CRP levels ≥4.67 mg/L were independent risk factors for recurrence post-laparoscopic myomectomy (OR=1.855, 1.038, 1.917, 1.208, 1.154, respectively; all P<0.05).</p><p><strong>Conclusion: </strong>The presence of ≥2 fibroids, intramural fibroids, and preoperative serum CRP levels ≥4.67 mg/L are identified as independent risk factors for the recurrence of uterine fibroids post-laparoscopic myomectomy. Regular follow-ups should be conducted for patients with these risk factors to timely detect potential recurrence risks and implement preventive and therapeutic measures accordingly. The number of fibroids, their location, and preoperative serum CRP level have a strong predictive ability for recurrence after laparoscopic myomectomy, effectively identifying patients with recurrence while excluding those without recurrence.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1157-1163"},"PeriodicalIF":2.5,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12035410/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143982784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Qualitative Study of Fertility Preservation Experience in Women with Breast Cancer. 乳腺癌妇女生育能力保存经验的定性研究。
IF 2.5 4区 医学
International Journal of Women's Health Pub Date : 2025-04-23 eCollection Date: 2025-01-01 DOI: 10.2147/IJWH.S517901
Zilian Wang, Xinyi Yang, Xia Hong, Yu He, Aike Xu, Xuechun Jiang, Qun Wei
{"title":"A Qualitative Study of Fertility Preservation Experience in Women with Breast Cancer.","authors":"Zilian Wang, Xinyi Yang, Xia Hong, Yu He, Aike Xu, Xuechun Jiang, Qun Wei","doi":"10.2147/IJWH.S517901","DOIUrl":"https://doi.org/10.2147/IJWH.S517901","url":null,"abstract":"<p><strong>Objective: </strong>To explore the experiences of women with breast cancer who have undergone fertility preservation and to explore the psychological needs of patients.</p><p><strong>Methods: </strong>Using descriptive phenomenological research methods, 11 patients who underwent oocyte or embryo cryopreservation after diagnosis of breast cancer were selected for semi-structured interviews in a tertiary care hospital. Themes were distilled using Colaizzi's 7-step analysis and reported according to COREQ guidelines.</p><p><strong>Results: </strong>The experiences of women with breast cancer who underwent fertility preservation can be categorized into 4 themes and 11 sub-themes: a. Physical pain and discomfort (physiological pain, tolerance of physical discomfort); b. heavy psychological burdens (fertility worries, self-blame and guilt, loneliness and helplessness, bias from others and self); c. Actively seeking and benefiting from ways of coping with illness (life over procreation; hope, confidence and courage; positive coping with illness; adequate social support; growth follow in adversity); d. Lack of fertility-related information support.</p><p><strong>Conclusion: </strong>Oncology and reproductive health professionals should pay attention to the experiences of breast cancer patients undergoing fertility preservation and target timely, scientific, and effective interventions to promote disease recovery and improve quality of life.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1143-1155"},"PeriodicalIF":2.5,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12034269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors Influencing Maternal Health Literacy in Postpartum Women. 影响产后妇女孕产妇健康素养的因素
IF 2.5 4区 医学
International Journal of Women's Health Pub Date : 2025-04-21 eCollection Date: 2025-01-01 DOI: 10.2147/IJWH.S511322
Alita Sangdang, Wanna Phahuwatanakorn, Piyanun Limruangrong
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