International Journal of Women's Health最新文献

{"title":"Efficacy and Acceptability of Thermal Ablation in Patients with Positive Documented Visual Inspection with Acetic Acid (Do-VIA) Results.","authors":"Siti Azizah, Gatot Purwoto, Laila Nuranna, Tricia Dewi Anggraeni, Tofan Widya Utami, Fahrina Fahrunnisa, Najmarani Devi Firdaus","doi":"10.2147/IJWH.S538321","DOIUrl":"https://doi.org/10.2147/IJWH.S538321","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the efficacy and acceptability of thermal ablation (TA) as a treatment modality in patients with positive Documented Visual Inspection with Acetic Acid (Do-VIA) results, in a low-resource clinical setting.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted at the VIA clinic of Cipto Mangunkusumo National Referral Hospital (RSCM), Jakarta, Indonesia, from January to July 2024. Patients with positive VIA-DoVIA results were treated with thermal ablation therapy (also known as cold coagulation) and followed up for three months to assess clinical outcomes and acceptability.</p><p><strong>Results: </strong>Out of 99 patients who underwent VIA screening, 47 tested positive. Of these, 35 received thermal ablation therapy. Three months post-treatment, 25 patients tested negative on VIA, while only 3 patients remained VIA-positive. Patient-reported side effects included clear vaginal discharge (52%), vaginal discharge with blood spots (3%), itchy discharge (38%), and short-term vaginal spotting (7%). No severe adverse events were reported.</p><p><strong>Conclusion: </strong>Thermal ablation therapy appears to be an effective and well-tolerated alternative to cryotherapy for the treatment of cervical precancerous lesions. It demonstrates good efficacy, minimal side effects, and high acceptability among healthcare providers in low-resource settings.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"3423-3427"},"PeriodicalIF":2.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12497378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145237910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Validation of Dynamic Nomograms for Predicting Delivery Mode and Neonatal Intensive Care Unit Admission in Intrapartum Fever: A Retrospective Cohort Study.","authors":"Jianzhi Ni, Dan Zhang, Yuling Ding, Hongmei Ding, Zvikomborero Panashe Rejoice Munemo, Hongxiu Zhang","doi":"10.2147/IJWH.S544623","DOIUrl":"https://doi.org/10.2147/IJWH.S544623","url":null,"abstract":"<p><strong>Background: </strong>While maternal intrapartum fever is linked to adverse neonatal outcomes, predictive tools for delivery mode and neonatal intensive care unit (NICU) admission in this population remain scarce.</p><p><strong>Objective: </strong>To develop and validate a dynamic nomogram predicting cesarean delivery and NICU admissions in women with intrapartum fever, facilitating individualized intrapartum decision-making.</p><p><strong>Methods: </strong>This retrospective cohort study analyzed 24,784 deliveries (2019-2021) at a tertiary center. After exclusions, 1,047 women with intrapartum fever were included in the study cohort. The dataset was randomly partitioned into training (n=837) and testing (n=210) sets. Backward stepwise multivariable logistic regression models were developed to predict cesarean delivery and neonatal intensive care unit admission. The discriminative capacity of the model was evaluated using receiver operating characteristic (ROC) curve analysis. Calibration performance was assessed via 1000 nonparametric bootstrap resamples to generate calibration curves, with systematic quantification of agreement between predicted probabilities and observed outcomes through the Brier score and Hosmer-Lemeshow goodness-of-fit test.</p><p><strong>Results: </strong>Predictors of cesarean delivery included advanced maternal age, hypertensive disorders, Intrapartum Antibiotic Prophylaxis (IAP), Meconium-Stained Amniotic Fluid (MSAF), Macrosomia, Postpartum Hemorrhage (PPH), Oligohydramnios, assisted reproductive technology (ART), Hypertensive Disorders of Pregnancy (HDP), Maternal tachycardia, Placental histopathology, intrapartum temperature and Method of inducing labor. Low Birth Weight (LBW), adverse obstetric history (AOH), Fetal tachycardia, Fetal bradycardia, Scarred uterus, Maternal tachycardia and MSAF predicted neonatal intensive care unit admission. The cesarean delivery model achieved AUC of 0.8 (training) and 0.783 (testing); the neonatal intensive care unit admission model showed AUC of 0.681 (training) and 0.748 (testing).</p><p><strong>Conclusion: </strong>This nomogram provides a clinically useful tool to predict delivery mode and neonatal intensive care unit admission in women with intrapartum fever, aiding risk stratification and improving perinatal outcomes.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"3385-3400"},"PeriodicalIF":2.6,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12495972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HPV Infection in Women with ASC-US in Eastern Marmara, Türkiye: Genotype Prevalence and Clinical Implications.","authors":"Gunel Guliyeva, Osman Köse","doi":"10.2147/IJWH.S550450","DOIUrl":"https://doi.org/10.2147/IJWH.S550450","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to retrospectively evaluate the distribution of human papillomavirus (HPV) genotypes, age-specific prevalence, and their association with histopathological outcomes in women with cervical cytology results reported as atypical squamous cells of undetermined significance (ASC-US) and concurrent high-risk HPV (hr-HPV) positivity.</p><p><strong>Patients and methods: </strong>Among 39,189 records screened between October 2019 and October 2024, 705 patients with ASC-US and hr-HPV positivity were included. HPV genotyping was performed using real-time PCR, cytological evaluation followed the Bethesda System, and colposcopic biopsies were classified according to the Lower Anogenital Squamous Terminology (LAST) guidelines.</p><p><strong>Results: </strong>HPV-16 (25.6%), HPV-51 (7%), and HPV-31 (6.5%) were the most prevalent genotypes, detected in 28.2% (n=199) of hr-HPV-positive cases. HPV-16 demonstrated the strongest association with high-grade lesions, accounting for 47.6% of cervical intraepithelial neoplasia grade 2 or worse (CIN2+). Multiple HPV infections correlated with an elevated risk of CIN2+. Age-stratified analysis revealed HPV-16 predominance in women aged 40-49 years, whereas HPV-51 was more frequent in those ≥60 years.</p><p><strong>Conclusion: </strong>In ASC-US cases, HPV-16 is the predominant genotype and a significant predictor of high-grade cervical lesions. The unexpectedly high prevalence of HPV-51 and HPV-31 in this Turkish cohort underscores the importance of tailoring screening algorithms to regional genotype distributions. Furthermore, the observed age-specific variations in genotype prevalence highlight the need for age-adjusted management strategies.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"3401-3415"},"PeriodicalIF":2.6,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12495964/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Fertility Needs of Women Before and After Oocyte Freezing for Medical and Non-Medical Reasons: A Scoping Review.","authors":"Mansoureh Moaya, Shadab Shahali, Minoor Lamyian, Sayed-Mohammad Azin, Alireza Milanifar","doi":"10.2147/IJWH.S546534","DOIUrl":"https://doi.org/10.2147/IJWH.S546534","url":null,"abstract":"<p><strong>Objective: </strong>Oocyte cryopreservation represents an effective strategy for fertility preservation among women of reproductive age. The most consistent and robust body of evidence highlights female age at the time of oocyte retrieval as the single most critical biological determinant of reproductive outcomes. While fertility preservation enhances women's reproductive autonomy, it simultaneously presents significant challenges regarding the adoption and integration of this advanced technology.</p><p><strong>Methods: </strong>We reviewed seven databases to assess the fertility needs of women before and after oocyte freezing for medical and non-medical reasons. The inclusion criteria targeted studies on fertility preservation in women, excluding research involving men, adolescents, and transgender individuals. Out of the 2550 screened publications, 44 studies met the eligibility requirements and were included.</p><p><strong>Results: </strong>The synthesis revealed five key areas of reproductive needs for women before and after oocyte freezing. Included counseling and fertility-related information, decision-making support, and emotional care. Furthermore, obtaining informed consent and issues related to the secondary use of frozen eggs are critical considerations for healthcare providers.</p><p><strong>Conclusion: </strong>Realistic counseling is essential to ensure that women understand both the opportunities and limitations of oocyte freezing. Balanced, evidence-based guidance can help women make informed decisions while avoiding unrealistic expectations. Future efforts should focus on integrating fertility preservation education into public health strategies, expanding insurance or subsidy programs to reduce financial burden, and developing culturally sensitive counseling frameworks.</p><p><strong>Trial registration: </strong>This review was registered at PROSPERO with Registration ID: CRD42021223906.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"3361-3374"},"PeriodicalIF":2.6,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12493922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined Psychological Nursing and Midwife-Led Positional Care Reduces Labor Duration in Nulliparous Women: A Retrospective Study.","authors":"Jing Liu, Jiaqi Yang, Na Sun","doi":"10.2147/IJWH.S539612","DOIUrl":"https://doi.org/10.2147/IJWH.S539612","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effects of psychological nursing combined with midwife-led positional care on labor duration and delivery outcomes in nulliparous women undergoing vaginal delivery.</p><p><strong>Methods: </strong>This retrospective study included 110 nulliparous women who underwent vaginal delivery in our hospital's obstetrics department between August 2023 and January 2025. Participants were divided into an observation group (n = 55, receiving psychological nursing combined with midwife-led positional care) and a control group (n = 55, receiving routine nursing interventions). Labor duration, sense of labor control, anxiety/depression scores, health knowledge mastery, and self-efficacy were compared between the two groups.</p><p><strong>Results: </strong>No significant differences were observed in baseline clinical characteristics (eg, age) between the groups (P > 0.05), indicating comparability. The observation group exhibited significantly shorter labor durations during both the first and second stages of labor compared to the control group (402.65 ± 61.51/39.78 ± 5.91 vs 311.56 ± 50.69/26.58 ± 5.31, P < 0.05). Scores on the Labor Control Scale were markedly higher in the observation group (141.56 ± 11.6 1 vs 68.54 ± 12.61, P < 0.05). Post-intervention, the observation group reported lower anxiety (HAMA) and depression (HAMD) scores than the control group (13.14 ± 2.11/10.65 ± 1.45 vs 8.25 ± 1.52/7.34 ± 1.28, P < 0.05). Health knowledge levels regarding childbirth were significantly superior in the observation group (78.23 ± 5.56 vs 90.11 ± 5.14, P < 0.05), as were post-intervention CBSEI-C32 self-efficacy scores (88.23 ± 2.88 vs 98.56 ± 1.17, P < 0.05).</p><p><strong>Conclusion: </strong>The integration of psychological nursing with midwife-led positional care effectively shortens labor duration, enhances health knowledge mastery and sense of labor control, alleviates negative emotions, and improves self-efficacy in nulliparous women. This joint intervention plan has empirical basis for clinical implementation.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"3375-3383"},"PeriodicalIF":2.6,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12493099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Prognostic Factors for Overall Survival in Patients Undergoing Radical Radiotherapy for Cervical Cancer.","authors":"Fangfang Hao, Nanfeng Xiao, Meng Wang, Houyi Sang, Judong Luo, Jing Song","doi":"10.2147/IJWH.S543995","DOIUrl":"https://doi.org/10.2147/IJWH.S543995","url":null,"abstract":"<p><strong>Objective: </strong>Cervical carcinoma (CC) represents the predominant malignancy affecting the female population, with patient outcomes being a critical focus of clinical investigation. This research conducts a comprehensive evaluation of the clinical determinants influencing short-term survival rates in CC patients receiving definitive radiotherapy treatment.</p><p><strong>Methods: </strong>A total of 99 cervical cancer patients who received radical radiotherapy between April 2017 and March 2022 at two medical institutions were retrospectively examined. Clinical outcomes were evaluated using the Kaplan-Meier method and the Cox proportional hazards model.</p><p><strong>Results: </strong>A total of ninety - nine patients with cervical cancer who received radical radiotherapy were included in the study. The overall survival (OS) rate at 2 - year follow - up was 77.8%.COX unifactorial and multifactorial showed that the analysis of prognostic-related factors suggested that the higher the history of miscarriage and FIGO stage, the lower 2-year OS, and that the history of miscarriage and FIGO stage were independent factors affecting the short-term overall survival, and the difference of all of them was statistically significant (P < 0.05).</p><p><strong>Conclusion: </strong>A history of miscarriage and the FIGO classification stage serve as independent predictors of overall survival (OS) during the initial 24-month period for cervical carcinoma patients undergoing definitive radiotherapy. This study conducted a comprehensive analysis of short-term prognostic indicators for cervical squamous cell carcinoma patients undergoing radical chemoradiotherapy.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"3347-3359"},"PeriodicalIF":2.6,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12493931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145232488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations Between the Number of Vaginal Delivery and Urinary Incontinence in Women Before and After Natural Menopause: A Cross-Sectional Study.","authors":"Xuejiao Bai, Guanghui Li, Dongxia Yang, Hongli Ma, Hongxia Zhao, Xinming Yang","doi":"10.2147/IJWH.S537859","DOIUrl":"10.2147/IJWH.S537859","url":null,"abstract":"<p><strong>Purpose: </strong>Urinary Incontinence (UI) associates with menopausal status and vaginal delivery (VD). Existing literature has not confirmed a cumulative effect of an increasing number of VDs on UI incidence, while hormonal changes following natural menopause modulate the risk of UI. This study investigate the association between the number of VDs and UI by stratifying women based on menopausal status.</p><p><strong>Patients and methods: </strong>This study examined the relationship between the number of VDs and categories of UI, including Stress Urinary Incontinence (SUI), Urge Urinary Incontinence (UUI), and Mixed Urinary Incontinence (MUI) in pre- and postmenopausal women, utilizing publically accessible data from the National Health and Nutrition Examination Survey (NHANES, 2007-2018). Weighted multivariable logistic regression, restricted cubic splines (RCS), and subgroup analyses with interaction tests were used to examine their association.</p><p><strong>Results: </strong>This study comprised 4,046 premenopausal and 2,698 postmenopausal women. Adjusted multivariable regression analysis (Model 2) revealed that compared to nulliparous women, the risk of SUI significantly increased with ≥1 VDs in premenopausal women (1 VD: OR=2.53; 2 VDs: OR=3.73; ≥3 VDs: OR=2.94; all P<0.001) and with ≥2 VDs in postmenopausal women (2 VDs: OR=1.52; ≥3 VDs: OR=1.62, all P<0.05). MUI risk was elevated at 2 VD in both premenopausal (OR=1.78, P=0.012) and postmenopausal women (OR=1.57, P=0.049). No significant association was detected between the number of VDs and UUI in either group. RCS modeling revealed inverse U-shaped relationships between the number of VDs and SUI risk and L-shaped relationships with MUI risk across both groups (nonlinear P < 0.001).</p><p><strong>Conclusion: </strong>The number of VDs exhibits positive associations with incident SUI and MUI, while no significant association was detected with UUI. Notably, the additional risk for SUI and MUI associated with the number of VDs was attenuated in postmenopausal women compared to premenopausal women. Prospective studies are warranted to validate the robustness of these associations.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"3315-3330"},"PeriodicalIF":2.6,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12482943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145206568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single-Cell Transcriptomic Analysis Highlights the Impact of NFKB2-Mediated MIF-CD44 Signaling Axis in Endometrioid Endometrial Cancer.","authors":"Lu Zhang, Mengjie Yang, Quan Zhang, Yiqian Zhang, Qiyuan Li, Qionghua Chen","doi":"10.2147/IJWH.S530666","DOIUrl":"10.2147/IJWH.S530666","url":null,"abstract":"<p><strong>Background: </strong>The tumor microenvironment (TME) is a complex network driving endometrioid endometrial cancer (EC) progression. Previous analyses of the EC TME were often limited by a lack of detailed cellular annotations. Integrating single-cell RNA sequencing (scRNA-seq) data offers a comprehensive approach to reconstruct the TME, aiming to uncover novel mechanisms and therapeutic targets.</p><p><strong>Methods: </strong>We integrated public scRNA-seq data from 15 EC and 5 normal endometrium samples. Through detailed cell annotation, we performed comprehensive bioinformatic analyses, including pseudotime trajectories, copy number variation, and cell communication, to investigate mechanisms of EC development.</p><p><strong>Results: </strong>We identified nine cell types and characterized subpopulations of epithelial, macrophage, lymphocyte, and stromal fibroblast cells. The SOX9+LGR5- epithelial subtype showed elevated malignancy and NFKB pathway enrichment. The M2_like2 macrophage subtype played a critical role, engaging in robust MIF-(CD74+CD44) mediated communication with SOX9+LGR5- cells. Experimental validation confirmed MIF co-expression with E-cadherin in EC tissues. Furthermore, the transcription factor NFKB2 was found to mediate MIF's effect on the CD44 receptor in malignant epithelial cells. A pericyte-to-fibroblast transition in stromal cells may also support tumor growth, while an increase in CD8 exhausted/Treg cells and a decrease in cytotoxic CD8 cells suggest potential immune evasion.</p><p><strong>Conclusion: </strong>Our single-cell analysis details the EC TME landscape, revealing robust communication between M2_like2 macrophages and SOX9+LGR5- epithelial cells. We highlight a key mechanism where NFKB2 mediates MIF's pro-tumorigenic effects via the CD44 receptor, offering new insights into EC progression and potential therapeutic targets.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"3293-3313"},"PeriodicalIF":2.6,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12484105/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research Trends and Hotspots in Minimally Invasive Gynecologic Surgery: A Bibliometric and Visualization Analysis.","authors":"Tong Wu, Kebing Nie, Yueyue Gao, Ying Chen, Jinfeng Yan, Shixuan Wang, Jinjin Zhang","doi":"10.2147/IJWH.S522821","DOIUrl":"10.2147/IJWH.S522821","url":null,"abstract":"<p><p>Minimally invasive gynecologic surgery (MIGS) has changed gynecologic care over the past thirty years by introducing techniques like multiport laparoscopy, robotic-assisted laparoscopy, and single-site surgery. MIGS offers advantages like reduced blood loss, shorter recovery times, and comparable oncological outcomes to open surgery. However, existing literature lacks a systematic synthesis of global research trends and academic performance of researchers. This cross-sectional bibliometric analysis examined 5,379 MIGS-related publications indexed in the Web of Science Core Collection database spanning 2014 to 2023, utilizing tools like VOSviewer and CiteSpace to map academic trends. The study revealed global contributions from 1,888 institutions across 97 countries, with the United States (1,156 publications) and China (1,090 publications) emerging as leading contributors. High-income countries dominated research output, though metrics varied regionally. Key institutions driving innovation included Mayo Clinic (n = 97), Harvard Medical School (n = 87), and Brigham & Women's Hospital (n = 83). Journal performance showed disparities influenced by impact factors, accessibility, and editorial focus, while research hotspots centered on endometriosis, laparoscopy, and hysteroscopy. The findings highlight a dynamic, collaborative global landscape in MIGS research, with disease prevalence and journal specialization shaping academic priorities. This analysis underscores the field's evolution and anticipates future directions, emphasizing the role of multidisciplinary collaboration and technological advancements in advancing clinical practice.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"3331-3345"},"PeriodicalIF":2.6,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12484104/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global Mapping and Visualization Analysis of Almost Five Decades of Egg Freezing Research: Trends, Hotspots and Prospects.","authors":"Xiandong Peng, Hongxia Sun, Jiazhou Chen","doi":"10.2147/IJWH.S529541","DOIUrl":"10.2147/IJWH.S529541","url":null,"abstract":"<p><strong>Background: </strong>Egg freezing, also known as oocyte cryopreservation, has become an increasingly significant topic in reproductive medicine. A large number of articles have been published on egg freezing; however, there is still a lack of studies that use visualization methods for bibliometric analysis of relevant literature. This study aimed to explore the publication landscape and identify key trends, influential authors, institutions, and emerging topics in egg freezing research using bibliometric analysis.</p><p><strong>Methods: </strong>Publications related to egg freezing from 1979 to 2024 were retrieved from the Web of Science Core Collection. A bibliometric analysis was conducted using Excel 365, VOSviewer (version 1.6.20), CiteSpace (version 6.3.R1), and R 4.3.3 to map co-authorship networks, institutional collaborations, and keyword co-occurrence patterns.</p><p><strong>Results: </strong>A total of 1072 publications were identified, with an annual growth rate of 9.68%. The research was contributed by 4392 authors and originated from 1380 institutions in 59 countries. The United States leads with 337 publications accounting for 31.4%, followed by Italy and China. The Royal Women's Hospital in Australia was prominent institutional contributors. Oktay Kutluk. ranks first with 18 articles published and a 18 H-index. The leading journals included <i>Fertility and Sterility, Reproductive Biomedicine Online</i>, and <i>Human Reproduction</i>. Keywords analysis identified three clusters, including egg freezing technology, fertility preservation for young women scheduled for chemotherapy, and social recognition on egg freezing. The most recent occurring keywords were \"outcome\", \"infertility\", and \"knowledge\", indicating core areas of research focus in the future.</p><p><strong>Conclusion: </strong>This bibliometric analysis provides valuable insights into the global trends and research hotspots in egg freezing. The research highlights a growing focus on the technological aspects of egg freezing. Moving forward, researchers should focus on the social aspects of egg freezing, such as public education and awareness regarding egg freezing options.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"3241-3257"},"PeriodicalIF":2.6,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12478218/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145199321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}