International Journal of Women's Health最新文献

{"title":"The Global Burden of Polycystic Ovary Syndrome in Women of Reproductive Age: Findings from the GBD 2019 Study.","authors":"Bengui Jiang","doi":"10.2147/IJWH.S490836","DOIUrl":"https://doi.org/10.2147/IJWH.S490836","url":null,"abstract":"<p><strong>Purpose: </strong>Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder and the primary cause of anovulatory infertility among women aged 15-49 years. Despite its significance, it has been largely overlooked in global health discussions, with persistently high prevalence and incidence rates. This public health challenge necessitates attention both domestically and internationally. Between 1990 and 2017, the age-standardized prevalence of female infertility and associated DALYs rose by 0.70% and 0.396%, respectively. Economically, addressing women's endocrine and metabolic health can bolster the overall well-being of the female population using existing resources. For judicious utilization of available resources, data regarding the burden of PCOS is pivotal for comprehending women's health status and for devising and refining policies related to women's endocrine health. Consequently, this study scrutinizes and assesses the age-standardized PCOS incidence rate and DALYs for 1990 and 2019, traces the trends of these metrics from 1990 to 2019, examines the composition of various populations and diseases, and offers international comparisons. This aims to furnish critical insights for future health policy development and adjustments in the realm of female endocrine and metabolic health.</p><p><strong>Patients and methods: </strong>This study employed the Global Health Data Exchange to obtain PCOS burden data based on GBD 2019. It collected incidence, DALYs, and age-standardized rates (ASRs) from 1990 to 2019 across global, regional, national, and SDI quintile levels, spanning 21 regions and 204 countries. To analyze trends, ASRs and estimated annual percentage changes (EAPCs) were calculated, with standardization crucial for comparability. EAPC was derived using a generalized linear model with a Gaussian distribution.</p><p><strong>Results: </strong>The global burden of PCOS increased significantly from 1990 to 2019, with estimated annual percentage change (EAPCs) of 0.56 for incidence and 0.83 for DALYs. The highest incidence rates were observed in the High-income Asia Pacific region, particularly in Japan and New Zealand, while the lowest rates were in Central Europe. Equatorial Guinea and Qatar exhibited the most pronounced increases in incidence and DALYs, attributed to urbanization and enhanced healthcare infrastructure. The incidence and DALYs of PCOS showed variation across SDI quintiles, with the greatest burden found in the middle-SDI quintile. Women between the ages of 20-29 years had the highest incidence and DALYs, emphasizing the importance of targeted interventions during this critical period. In contrast, regions with lower SDI levels, such as Central and Eastern Europe, reported the lowest burdens of PCOS, likely due to underdiagnosis and limited healthcare resources.</p><p><strong>Conclusion: </strong>From 1990 to 2019, there was a significant increase in the global burden of PCOS, with variations seen across ","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"153-165"},"PeriodicalIF":2.5,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11776423/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corticosteroid Phobia: A Key Barrier to Treatment in Young Women with Idiopathic Granulomatous Mastitis.","authors":"Weiyi Lin, Qiuzhou Wang, Jia Liu, Qiuwen Tan","doi":"10.2147/IJWH.S500846","DOIUrl":"https://doi.org/10.2147/IJWH.S500846","url":null,"abstract":"<p><strong>Purpose: </strong>Corticosteroids are recommended as a first-line treatment for idiopathic granulomatous mastitis (IGM), a disease that usually occurs in young women. Corticosteroid phobia is a fear of corticosteroids and one of the main reasons for poor treatment compliance. Despite the increasing recognition of corticosteroid phobia, there has been a lack of studies on this issue in IGM. This study was designed to investigate the prevalence and degree of corticosteroid phobia in IGM patients.</p><p><strong>Patients and methods: </strong>A cross-sectional survey was conducted among IGM patients who were receiving treatment at West China Hospital between June 2023 and December 2023. A modified version of Topical Corticosteroid Phobia Scale (TOPICOP) was used to assess the prevalence and degree of corticosteroid phobia in patients with IGM. Sources of drug information were also identified. Scores were expressed as mean ± standard deviation. Independent <i>t</i>-test was used to compare the TOPICOP item scores between different categorical variables.</p><p><strong>Results: </strong>A total of 50 IGM patients were included in the present study. The median global TOPICOP score was 61.29 ± 11.71%. About 80% of patients represented with severe phobia, which their global TOPICOP score was above 50.0%. About 50% of participants showed fear of adverse effect of oral corticosteroids. About 89.6% of participants who received corticosteroid treatment showed their well to adhere to the doctor's advice. IGM patients with systemic symptoms were associated with higher scores in the behavior domain and/or global TOPICOP. Young, low educated, and unemployed individuals were more likely to have corticosteroid phobia (p < 0.05). There was no difference in the scores based on skin redness, abscess formation, ulcer or fistula, initial treatment choice, or monthly household income. Medical professionals were the primary sources of information about corticosteroid.</p><p><strong>Conclusion: </strong>Corticosteroid phobia was highly prevalent among the women with IGM, as well as the high treatment adherence. Women showed a high preference for non-corticosteroid therapies as alternative therapies. Providing more comprehensive and professional knowledge by physicians might be an effective method to attenuate corticosteroid phobia.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"167-177"},"PeriodicalIF":2.5,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11776503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traditional and Non-Traditional Risk Factors of Acute Coronary Syndrome in Young Women: Evidence from the ANCORS-YW Study.","authors":"Rasheed Ibdah, Mohammed Al-Nusair, Raghad Abuhalimeh, Saad A Mahmoud, Bushra Laswi, Sukaina Rawashdeh, Ayman Hamoudeh, Khalid A Kheirallah","doi":"10.2147/IJWH.S479229","DOIUrl":"10.2147/IJWH.S479229","url":null,"abstract":"<p><strong>Purpose: </strong>Young women are at risk of acute coronary syndrome (ACS). They represent a unique population exposed to traditional cardiovascular risk factors and female sex-specific, non-traditional risk factors. The current study aimed to describe traditional and non-traditional risk factors of ACS in young women from the Middle East.</p><p><strong>Patients and methods: </strong>The present study used data from the Jordanian, nationwide, multicenter, case-control study, ANCORS-YW. Bivariate analyses and logistic regression models were used to predict independent risk factors of ACS using adjusted odds ratios (AOR) and 95% confidence intervals (CI).</p><p><strong>Results: </strong>The study included 572 young women (≤50-years) with a median age of 45-years, divided into an ACS group (n=154, 26.9%) and a control group with no atherosclerotic cardiovascular disease (n=418, 73.1%). The most common presentation of ACS was non-ST-elevation ACS (n=98, 64%). The ACS group, compared to control group, had higher proportions of type-2 diabetes (41.6%vs.11.7%, p<0.001), hypertension (53.9%vs.23.4%, p<0.001), tobacco use (37.7%vs.24.2%, p=0.001), family history of cardiovascular disease (53.2%vs.23.4%, p<0.001), metabolic syndrome (14.3%vs.2.4%, p<0.001), and preterm delivery (24.7%vs.16.7%, p=0.032). ACS group had nonsignificantly greater proportions of hypertensive disorders of pregnancy (29.2%vs.22.7%, p=0.109) and gestational diabetes (15.6%vs.10.3%, p=0.081). Multivariable logistic regression analyses identified five independent predictors of ACS: type-2 diabetes (AOR, 95% CI: 3.45, 1.98─5.99), family history of cardiovascular disease (3.33, 2.15─5.17), tobacco use (2.01, 1.26─3.21), hypertension (1.72, 1.07─2.78), and metabolic syndrome (4.35, 1.72─11.03).</p><p><strong>Conclusion: </strong>Modifiable risk factors play an important role in ACS risk among young women. Efforts should be made to improve primordial and primary prevention in this population.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"139-152"},"PeriodicalIF":2.5,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11774101/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Case of Metachronous Clear Cell Ovarian Carcinoma and Thyroid Carcinoma: Clinical and Pathological Insights.","authors":"Steven Ridwan, Ali Budi Harsono, Dodi Suardi, Andi Kurniadi, Kemala Isnainiasih Mantilidewi, Yudi Mulyana Hidayat","doi":"10.2147/IJWH.S477189","DOIUrl":"10.2147/IJWH.S477189","url":null,"abstract":"<p><strong>Background: </strong>Clear cell ovarian carcinoma (CCOC) is a type of epithelial ovarian cancer, representing 5-11% of ovarian cancers. CCOCs tend to occur in the fifth to seventh decades of life, with only 10% of cases occurring in the fourth decade. On the other side, papillary thyroid carcinoma is the most common histology type of thyroid carcinoma and is associated with locoregional spread. Herein, we present a rare case of double-primer ovarian and thyroid cancer, which is a clear cell ovarian carcinoma metachronous with papillary thyroid carcinoma.</p><p><strong>Case report: </strong>A 47-year-old nulliparous woman presented to our Gynecology Oncology facility with an abdominal mass that had progressively increased in size over the last three months. She had a history of papillary thyroid cancer ten years previously and was treated with radioiodine (I-131). Physical examination revealed an immobile abdominal cystic mass measuring 20 × 18 × 15 cm. Ultrasound imaging revealed a cystic mass with a solid part, measured 16.1 × 10.9 × 12.84 cm, with M4 feature of the IOTA simple rule. CA-125 tumor marker levels were 190.1 U/mL. Ovarian cancer was suspected, and surgical staging with total hysterectomy, bilateral salpingo-oophorectomy, omentectomy, frozen sectioning, and adhesiolysis was performed. Histopathological examination revealed a clear cell ovarian carcinoma.</p><p><strong>Discussion: </strong>Papillary thyroid carcinoma tends to be a locoregional metastasis, whereas distant metastases are rare. Distant metastasis often occurs decades after the primary tumor, with the most common metastatic sites being the lungs and bones. This raises an important clinical question concerning the etiology of the ovarian carcinoma: whether it represents a metastasis from the pre-existing thyroid carcinoma or a distinct primary neoplasm. Determining the precise relationship between these malignancies is crucial for guiding treatment strategies and understanding the biological behavior of the tumors involved. In this case, clear cell ovarian carcinoma arose separately from papillary thyroid carcinoma.</p><p><strong>Conclusion: </strong>Double primer cancer of the ovary and thyroid, which is a clear cell ovarian carcinoma metachronous with papillary thyroid carcinoma, is possible.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"119-125"},"PeriodicalIF":2.5,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11766383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Qualitative Exploration of Emotional Experiences in Patients with Thin Endometrium Undergoing Repeated Cancellations of Frozen-Thawed Embryo Transfer Cycles.","authors":"Qun Wei, Xia Hong, Yu He, Meiling Xu, Xuechun Jiang, Xuling Shen, Zilian Wang","doi":"10.2147/IJWH.S500794","DOIUrl":"10.2147/IJWH.S500794","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to investigate the emotional experience of patients with thin endometrium (TE) who have repeatedly cancelled their cycles due to unsuitability for embryo implantation during the endometrial preparation phase of freeze-thaw embryo transfer (FET). The overall aim is to improve management strategies and quality of life for these patients.</p><p><strong>Methods: </strong>A descriptive phenomenological methodology was utilized to conduct in-depth, semi-structured interviews with ten patients diagnosed with TE who had experienced repeated FET cancellations between January and June 2024. The emotional responses elicited were systematically analyzed to identify core themes.</p><p><strong>Results: </strong>Four primary themes emerged: 1) a spectrum of negative emotional responses; 2) deterioration in marital relationships; 3) a pronounced need for professional support, including a) expanded treatment options and b) informational guidance; and 4) diverse coping mechanisms employed by patients.</p><p><strong>Conclusion: </strong>Healthcare providers must recognize and address the complex emotional responses associated with repeated transfer cancellations in patients with TE. Tailored psychological interventions and comprehensive support services may not only foster emotional well-being but also potentially improve clinical outcomes in assisted reproductive technology (ART) settings.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"127-137"},"PeriodicalIF":2.5,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11766209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Allometric Body Shape Indices and Osteoporosis in Postmenopausal Women: A Cross-Sectional Study from NHANES.","authors":"Songfeng Zhao, Xin Pan","doi":"10.2147/IJWH.S490741","DOIUrl":"10.2147/IJWH.S490741","url":null,"abstract":"<p><strong>Background: </strong>Osteoporosis is a common health concern in postmenopausal women. Obesity, commonly assessed using body mass index (BMI), may have a protective effect on osteoporosis in postmenopausal women. As BMI is limited to the distinguishing fat accumulation, the study aimed to explore the association between allometric body shape indices [including a body shape index (ABSI), hip index, (HI), and waist-hip index (WHI)] and osteoporosis in postmenopausal women.</p><p><strong>Methods: </strong>Postmenopausal women aged >50 years in the National Health and Nutrition Examination Survey from 2017 through 2020 (revised to 01/2017 through 12/2020) were included. Potential covariates were selected using the univariate logistic regression models. The association between allometric body shape indices and osteoporosis was explored using weighted univariate and multivariate logistic regression models, with results presented as odds ratios (ORs) and 95% confidence intervals (CIs). The association was further explored in different age and BMI populations. Area under the curve (AUC) analysis was conducted to evaluate the predictive performance of WHI.</p><p><strong>Results: </strong>In total, 810 postmenopausal women aged >50 years were included. Among them, 597 (73.70%) women have osteoporosis. WHI ≥0.094 (OR = 2.07, 95% CI: 1.14-3.78) was associated with higher odds of osteoporosis in postmenopausal women. BMI ≥30 kg/m² (OR = 0.23, 95% CI: 0.11-0.50) was also related to decreased odds of osteoporosis. ABSI ≥85.74 was related to a higher incidence of osteoporosis in women aged ≥70 years (OR = 4.18, 95% CI: 1.22-14.35) and BMI ≥30 kg/m² (OR = 4.25, 95% CI: 1.82-9.95). The WHI has a better predictive performance with an AUC of 0.656 (95% CI: 0.613-0.699) than the waist-hip ratio.</p><p><strong>Conclusion: </strong>Higher WHI was associated with an increased incidence of osteoporosis in postmenopausal women. Higher ABSI was related to a higher incidence of osteoporosis in women aged ≥70 years and those with a BMI ≥30 kg/m². WHI could predict the incidence of osteoporosis in postmenopausal women.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"109-118"},"PeriodicalIF":2.5,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11766363/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distribution and Related Influencing Factors of AMH Level in Family-Planning Women of Childbearing Age: A Cross-Sectional Study from Beijing, China.","authors":"Jinwei Song, Songkun Gao, Lixia Zhao, Xiaolong Tong","doi":"10.2147/IJWH.S499220","DOIUrl":"10.2147/IJWH.S499220","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to analyze the distribution and factors influencing anti-Müllerian hormone (AMH) levels among family-planning women of childbearing age in Beijing, China.</p><p><strong>Patients and methods: </strong>We collected the data of 3,236 family-planning women of childbearing age who underwent pre-pregnancy examinations at Xicheng District Maternal and Child Health Hospital in Beijing between October 2021 and July 2024. Collected data included age, education level, ethnicity, height, weight, and systolic and diastolic blood pressure. We calculated the body mass index (BMI) of each participant. The collected blood test results included AMH, fasting blood glucose (FBG), thyroid-stimulating hormone (TSH), creatinine (Cr), and alanine aminotransferase, and hemoglobin levels and platelet count. A structured questionnaire was used to document the subjects' dietary and lifestyle habits, environmental factors, and emotional and mental stress statuses. The patients were divided into age groups (≥36 years versus ≤35 years) and factors compared between them. Two different factors influencing AMH level were analyzed using a logistics model.</p><p><strong>Results: </strong>The AMH level decreased with age, with a median AMH of <2.0 ng/mL for subjects aged ≥36 years. Significant intergroup differences were noted in ethnicity, education level, FBG, creatinine level, BMI, diastolic blood pressure, hemoglobin level, smoking rate, and life-related stress level. A logistic regression analysis suggested that age was a negative factor affecting AMH level in both groups (P=0.000 and 0.002, respectively). Hemoglobin and educational levels were also important influential factors of AMH in patients aged ≤ 35 years but not in those aged ≥ 36 years.</p><p><strong>Conclusion: </strong>AMH levels gradually decreased with age. Although nutritional status and educational level significantly impacted AMH levels among women ≤ 35 years of age, their effects decreased thereafter. Thus, 35 years of age is considered an important reproductive boundary for women of childbearing age.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"99-107"},"PeriodicalIF":2.5,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11766139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What are the Thoughts of Women Whose Husbands' Frozen Testicular Sperm Is Thawed for in vitro Fertilization on the Day of Oocyte Retrieval? A Qualitative Study.","authors":"Yu He, Qun Wei, Xiaojie Chen, Chen Zhang, Zilian Wang","doi":"10.2147/IJWH.S505757","DOIUrl":"10.2147/IJWH.S505757","url":null,"abstract":"<p><strong>Objective: </strong>The psychological experiences will be analyzed to understand the needs and burdens of women on the day of oocyte retrieval when the thawed testicular sperm of their husbands is used for in vitro fertilization, in order to provide a basis for the subsequent formulation of relevant nursing measures.</p><p><strong>Methods: </strong>This study utilized a descriptive phenomenological research approach. A cohort of 13 women undergoing oocyte retrieval on the day when thawed testicular sperm from their husbands is used for in vitro fertilization at the Reproductive Medicine Center of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, between August and October 2024, were chosen as participants for this study. Semi-structured, in-depth interviews were conducted to gather qualitative data. The Colaizzi 7-step analysis method was subsequently utilized to analyze the interview transcripts and identify emerging themes.</p><p><strong>Results: </strong>The analysis yielded 3 themes: (1) facing challenges and requiring assistance (a. demonstrate a strong desire to acquire professional knowledge; b. demonstrate a strong desire for recognition); (2) overwhelming psychological stress (a. concerns about potential privacy breaches; b. concerns about security issues; c. concerns about the therapeutic efficacy); (3) improving family atmosphere and marital relationships (a. communication between couples has increased.; b. shared expectations for children help couples establish a common goal).</p><p><strong>Conclusion: </strong>It is recommended that healthcare practitioners implement strategies to enhance patient education and awareness surrounding assisted reproductive technology. Additionally, establishing and strengthening social support, reinforcing privacy protections and safety measures, promoting effective communication between partners, and managing treatment outcome expectations are crucial steps forward.</p><p><strong>Immediate practical implications: </strong>Women prioritize treatment efficacy, privacy preservation, and the necessity of acquiring comprehensive professional knowledge when employing their partner's testicular sperm for in vitro fertilization. The study is instrumental in shaping policy dialogues on reproductive health, highlighting the critical significance of women's psychological health in the realm of in vitro fertilization.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"87-98"},"PeriodicalIF":2.5,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11759575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Gestational Diabetes Mellitus on the Development of Preeclampsia in Twin Pregnancies: A Retrospective Cohort Study Conducted at a Tertiary Hospital.","authors":"Hanglin Wu, Lin Zhang, Zhen Xie, Hongxia Cai, Jindi Zhang, Liming Yu","doi":"10.2147/IJWH.S500531","DOIUrl":"10.2147/IJWH.S500531","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to examine the effects of gestational diabetes mellitus (GDM) on the risk of pregnancy complications in twin pregnancies and to investigate the relationship between glycemic levels and the risk of preeclampsia (PE) and abnormal fetal growth.</p><p><strong>Patients and methods: </strong>A retrospective cohort study of 736 twin pregnancies was conducted at a tertiary hospital. Propensity score matching and multivariable logistic models were utilized to compare maternal and neonatal outcomes between twin pregnancies with GDM and those without GDM. Multivariable logistic regressions were performed to address the intertwin correlation between glycemic levels and the primary outcomes.</p><p><strong>Results: </strong>There was no significant difference in the risk of PE between non-GDM and GDM pregnancies (OR, 0.70; 95% CI: 0.38-1.27; P = 0.238). No statistically significant differences were observed in the prevalence of small for gestational age and large for gestational age between the study groups. A comparative analysis of twin pregnancies affected by PE and GDM versus those without GDM revealed that the former group exhibited similar maternal and neonatal outcome risks. Women with fasting blood glucose levels from 5.1 mmol/L (92mg/dL) to less than 5.3 mmol/L (95.6mg/dL) had a significantly higher risk of PE compared with women without GDM (OR, 2.90; 95% CI: 1.12-7.51; P = 0.028). In subgroups of glycosylated hemoglobin (HbA1c), HbA1c ≥ 5.5% had the highest risk of PE in the second and third trimesters compared with women without GDM (OR, 4.90; 95% CI: 1.00-24.12; P = 0.05).</p><p><strong>Conclusion: </strong>The risk of PE was not increased in twin pregnancies complicated with GDM, but significantly increased in women with an HbA1c ≥5.5%. No significant associations were observed between the co-occurrence of GDM and PE and the incidence of pregnancy complications in twin pregnancies. Strict glycemic control may decrease the risk of PE in twin pregnancies with GDM.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"75-86"},"PeriodicalIF":2.5,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758866/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasonographic Assessment of Uterine Measurements and Endometrial Thickness Among Healthy Saudi Females Sample.","authors":"Mahasin G Hassan, Huda M Alnafa, Norah Alsofyan, Reham S Alsulimi, Sumayah Alsllal, Noura A Abaalkhail, Mona Alzurayr, Hessah Alamr, Tasneem S A Elmahdi, Asma S Aldahes, Mayson Wanasi, Halima Hawesa","doi":"10.2147/IJWH.S487564","DOIUrl":"10.2147/IJWH.S487564","url":null,"abstract":"<p><strong>Aim: </strong>The present study was conducted to analyze uterine measurements and endometrial thickness throughout the menstrual cycle in Saudi healthy females of reproductive age.</p><p><strong>Methods: </strong>This cohort study was conducted at Princess Nourah bint Abdulrahman University, Saudi Arabia, among thirty-three females of reproductive age who underwent trans-abdominal pelvic ultrasound scans across four menstrual cycle phases. Data analysis was conducted using SPSS version 26, utilizing descriptive statistics, one-way ANOVA, correlation, and regression analysis.</p><p><strong>Results: </strong>Endometrial thickness and layers showed significant variations (p<0.001) across menstrual phases (early proliferative: 0.59 ± 0.21 cm, late proliferative: 0.77 ± 0.24 cm, secretory: 1.09 ± 0.40 cm, menstrual: 0.52 ± 0.35 cm). Endometrial thickness was positively correlated with number of layers (r=0.576, p<0.05). The study showed that the average uterine length, width, and thickness were 7.33 ± 0.76 cm, 3.93 ± 1.00 cm and 3.44 ± 0.55 cm, which showed stability across menstrual phases, except for width showing slight variations. Endometrial thickness was positively correlated with uterine thickness (r=0.358, p<0.05).</p><p><strong>Conclusion: </strong>The study results emphasize the significance of using region-specific reference values in clinical practice. This approach would enable precise evaluation and treatment of gynecological problems. It is encouraged to do future study with larger populations in order to validate these results and improve the therapeutic applicability.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"67-73"},"PeriodicalIF":2.5,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11742739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}