International Journal of Women's Health最新文献

{"title":"UDP-Glucose Ceramide Glucosyltransferase Inhibition, Immune Cell Mediation, and Endometriosis Risk: A Mendelian Randomization Study.","authors":"Liqiu Xue, Rongjun Zhang, Jiaxing Chen, Xiaoxia Ge, Jiajing Chen","doi":"10.2147/IJWH.S509603","DOIUrl":"10.2147/IJWH.S509603","url":null,"abstract":"<p><strong>Purpose: </strong>Previous studies have reported a link between UDP-glucose ceramide glucosyltransferase (UGCG), immune regulation, and endometriosis (EM). We hypothesized that UGCG inhibitors might exert therapeutic effects on EM. Therefore, in this study, we performed a two-sample, two-step Mendelian randomization (MR) analysis modeling genetic variation of UGCG inhibitors to investigate the causal relationship between genetically determined <i>UGCG</i> inhibition, EM, and mediation of immune cells.</p><p><strong>Methods: </strong>Two-sample MR was conducted using genome-wide association study data on <i>UGCG</i> inhibition and EM. Furthermore, we adopted strict instrumental variable selection criteria to ensure the robustness of our results and primarily employed the inverse-variance weighted method, along with the weighted median, MR-Egger, and MR-PRESSO methods for sensitivity analyses. Additionally, a two-step MR analysis was performed to investigate the potential role of immune cells in mediating the relationship between <i>UGCG</i> inhibition and EM.</p><p><strong>Results: </strong><i>UGCG</i> inhibition was associated with a decreased EM risk, with an odds ratio of 0.915, 95% confidence interval of 0.859-0.975, and <i>P</i> = 0.006, demonstrating the robustness of our results and potential clinical significance of our study. Among 731 types of immune cells analyzed, 12 were significantly associated with <i>UGCG</i> inhibition and EM, 8 of which acted as mediators. Terminally differentiated CD4+ T cells (from the maturation stages of the T-cell panel) accounted for the highest proportion of mediating cells (26.727%), whereas immunoglobulin D (IgD) expression on IgD+ CD38^dim B cells (from the B-cell panel) accounted for the lowest proportion (7.816%).</p><p><strong>Conclusion: </strong>Inhibiting UGCG activity may reduce the risk of EM, and immune cells may mediate this effect. Our findings provide novel insights for the development of potential therapeutic strategies for EM treatment.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1497-1509"},"PeriodicalIF":2.5,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118494/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Characteristics of Non-Lactational Mastitis of Accessory Breast: A Case-Series Study.","authors":"Di Zhao, Dongxiao Zhang, Yifei Zeng, Na Fu, Xiaolong Xu","doi":"10.2147/IJWH.S512662","DOIUrl":"10.2147/IJWH.S512662","url":null,"abstract":"<p><strong>Background: </strong>Non-lactational Mastitis of Accessory Breast (NLM-AB) is a rare condition with limited research, leading to diagnostic challenges. Its clinical and demographic characteristics are poorly defined, and it is often confused with non-lactational mastitis (NLM), hindering effective diagnosis and treatment.</p><p><strong>Objective: </strong>This study aims to clarify the features of NLM-AB, distinguish it from NLM, and address key knowledge gaps to improve clinical diagnosis and patient management.</p><p><strong>Methods: </strong>We retrospectively analyzed data from 31 NLM-AB patients treated at Beijing Hospital of Traditional Chinese Medicine from January 2014 to September 2024. A 1:1 matched case-control study was conducted, comparing NLM-AB (case group) with 31 NLM patients (control group).</p><p><strong>Results: </strong>NLM-AB patients had a mean age of 36.68 ± 7.17 years and BMI of 23.10 ± 3.52. Most were married (83.87%) and had given birth (58.06%). All had axillary masses, with 85.19% showing skin changes. Statistically significant differences were found in marital status, reproductive history, breastfeeding duration, tumor size, and nipple retraction (P < 0.05). No significant differences were observed in nipple discharge, ulcer occurrence, or prolactin levels (P > 0.05).</p><p><strong>Conclusion: </strong>This study addresses a key clinical gap by identifying distinguishing features of NLM-AB, such as consistent axillary masses without nipple retraction and associations with reproductive history. These findings can directly support clinicians in early recognition and differential diagnosis of NLM-AB, avoiding unnecessary interventions targeting primary breast tissue. Incorporating these patient characteristics into diagnostic pathways may reduce misdiagnosis rates and guide more tailored treatment strategies, ultimately improving patient outcomes.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1485-1495"},"PeriodicalIF":2.5,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118479/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression and Clinical Significance of Irisin in Serum and Placenta Tissues of Pregnant Women with Severe Preeclampsia.","authors":"Yuxi Ren, Haining Bi, Ji Zhang, Qi Yin, Xue Zhang, Xuemei Gong, Yaojiao Li, Jifang Shi","doi":"10.2147/IJWH.S504035","DOIUrl":"10.2147/IJWH.S504035","url":null,"abstract":"<p><strong>Objective: </strong>Preeclampsia (PE) is a serious pregnancy-specific disorder that poses significant risks to maternal and fetal health, with severe preeclampsia (SPE) being a particularly life-threatening complication. The objective of this study is to investigate the effects and clinical significance of irisin in pregnant women with severe preeclampsia (SPE). Irisin levels in the serum and placental tissues of healthy pregnant women and those with early- and late-onset SPE were measured and compared.</p><p><strong>Methods: </strong>A total of 70 pregnant women treated at our hospital from January to November 2023 were selected for this study. The participants were divided into three groups: 20 women with early-onset severe preeclampsia (ES-PE group), 20 women with late-onset severe preeclampsia (LS-PE group), and 30 healthy pregnant women (control group). Fasting peripheral blood samples (5 mL) were collected from each participant, and placental tissues were obtained after delivery. Irisin levels in serum were measured using enzyme-linked immunosorbent assays (ELISA) with a commercial kit, and irisin expression in placental tissues was assessed by immunohistochemistry (IHC) with a rabbit anti-irisin antibody. The modes of delivery were also recorded.</p><p><strong>Results: </strong>The concentrations of irisin in both serum and placental tissues were significantly higher among pregnant women in the control group compared to the ES-PE and LS-PE groups. There was a significant difference between the control group and the ES-PE and LS-PE groups in the mode of delivery. Additionally, a significant positive correlation was identified between the serum irisin concentration and its differential expression in placental tissues, while there was a significant negative correlation between irisin levels in both serum and placental tissue and systolic and/or diastolic blood pressure.</p><p><strong>Conclusion: </strong>Reduced serum and placental irisin levels in pregnant women with SPE were associated with the onset and progression of SPE and may serve as a potential biological marker for SPE screening.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1473-1484"},"PeriodicalIF":2.5,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12103853/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perinatal Management of Neuromyelitis Optica Spectrum Disorder in Pregnancy: A Case Report.","authors":"Jue Wang, Rong Hu, Hao Zhu","doi":"10.2147/IJWH.S485822","DOIUrl":"10.2147/IJWH.S485822","url":null,"abstract":"<p><strong>Purpose: </strong>Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune inflammatory demyelinating disease of the central nervous system. Its onset and relapse are closely associated with pregnancy. The aim of this study was to evaluate the risks of NMOSD in the perinatal period.</p><p><strong>Patients and methods: </strong>A 35-year-old woman, gravida 4, para 1, at 21⁺⁴ weeks of gestation with NMOSD, was managed by a multidisciplinary team.</p><p><strong>Results: </strong>The patient was diagnosed with NMOSD five years prior to the current pregnancy, following an abortion. She had been treated with pulse steroids and plasma exchange at the time of diagnosis. She had a previous normal full-term delivery. Eight months before the onset of NMOSD, she had an induced abortion. She then experienced a relapse of her condition, complicated by embryonic arrest. During the current pregnancy, she had uneventful antenatal visits and was maintained on corticosteroids and intravenous immunoglobulin (IVIG) with no neurologic sequelae. She gave birth to a healthy male infant and her condition remained stable at follow-up.</p><p><strong>Conclusion: </strong>Women with NMOSD should consult with both neurologists and obstetricians to reduce the risk of pregnancy-related attacks.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1469-1472"},"PeriodicalIF":2.5,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12103194/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extremely High Systemic Immune Inflammation Levels Increase the Risk of All-Cause and Cardiovascular Mortality in Postmenopausal Women.","authors":"Fei Wu, Jiantong Yang, Yinchuan Liu, Yipei Zhang","doi":"10.2147/IJWH.S504664","DOIUrl":"10.2147/IJWH.S504664","url":null,"abstract":"<p><strong>Background: </strong>The systemic immune inflammation (SII) index provides a comprehensive assessment of inflammatory and immune status in patients with different diseases. However, it remains unclear whether the SII can be considered a valuable prognostic risk factor of all-cause mortality for postmenopausal women.</p><p><strong>Methods: </strong>We analyzed data from 1882 postmenopausal women enrolled in the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2018. The Systemic Immune-Inflammation Index (SII) was calculated using peripheral blood cell counts and categorized into quartiles. Multivariable Cox proportional hazards models and restricted cubic spline analyses were employed to assess the association between SII and mortality outcomes.</p><p><strong>Results: </strong>Over a median follow-up period of 8 years, 13.5% individuals died, with 4% deaths attributed to CVD. Patients with extremely high SII levels experienced significantly higher all-cause and CVD mortality. Compared to the low SII group (Q1), the hazard ratio (HR) and 95% confidence interval (CI) for all-cause mortality risk were 0.96 (0.87, 1.07), 0.97 (0.88, 1.08), and 1.28 (1.16, 1.41) for Q2, Q3, and Q4, respectively. Similarly, the HR (95% CI) for CVD mortality in Q2, Q3, and Q4 were 1.02 (0.83, 1.24), 1.11 (0.92, 1.34), and 1.32 (1.10, 1.58), respectively. Including SII in addition to traditional risk factors resulted in a slight enhancement in mortality prediction capability.</p><p><strong>Conclusion: </strong>Among postmenopausal women, extremely high SII levels were identified as an independent risk factor for all-cause and CVD mortality.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1457-1468"},"PeriodicalIF":2.5,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12103204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-Surgical Options for The Diagnosis of Endometriosis in Low-Resource Settings: A Comparative Study.","authors":"Dina Marlina, Aditya Utomo, Megawati Al'badly Ponco Dewi Poernomo, Putri Nadhira Adinda Adriansyah, Beni Samsul Amri, Artha Falentin Putri Susilo, Muhammad Alamsyah Aziz","doi":"10.2147/IJWH.S507556","DOIUrl":"10.2147/IJWH.S507556","url":null,"abstract":"<p><strong>Purpose: </strong>Endometriosis, a chronic estrogen-dependent condition characterized by the implantation of tissue beyond the uterine cavity, impacts 10% of women of reproductive age. Endometriosis manifests through menstrual discomfort, chronic pelvic pain, dyspareunia, and cyclical digestive issues. It is additionally linked to infertility. Early diagnosis and effective treatment are crucial but remain limited in many settings. This study aims to identify specific clinical characteristics that could aid in the early diagnosis and treatment of endometriosis.</p><p><strong>Patients and methods: </strong>The study conducted at Province General Hospital Margono, Indonesia, involved endometriosis patients who had registered from 2020 to 2024. Some inclusion and exclusion criteria are applied in this study. Statistical analysis was performed to determine the rate, odd ratio and prevalence ratio.</p><p><strong>Results: </strong>Our analysis indicates that women experiencing dysmenorrhea, particularly with an onset occurring more than three years after menarche, are significantly associated with endometriosis. Dysmenorrhea had nearly 17.5 times higher odds [OR 17.5, 95% CI 4.75-64.4, p-value 0.00] of being correlated with endometriosis, and the onset of dysmenorrhea more than 3 years after menarche had 1.67 times higher [OR 2.790; CI 95%; 1.011-7.698, p-value 0.045] of being associated with endometriosis.</p><p><strong>Conclusion: </strong>Multiple studies have shown that diagnosing endometriosis early is challenging due to its various symptoms. Our findings highlight the significance of dysmenorrhea characteristics, particularly its onset timing, as potential indicators of endometriosis. This findings suggest that incorporating dysmenorrhea onset into clinical assessments may enhance non-surgical diagnostic approaches, facilitating earlier detection and management of endometriosis.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1445-1456"},"PeriodicalIF":2.5,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12102738/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between the Chinese Visceral Adiposity Index and the Self-Reported Menopausal Status: Results from Two Nationally Representative Population-Based Studies.","authors":"Chunlin Dong, Ding Ma, Ke Gu, Yaying Lin, Jing Song, Yuan Wang, Jinjin Yu, Yanjun Zhou","doi":"10.2147/IJWH.S514304","DOIUrl":"10.2147/IJWH.S514304","url":null,"abstract":"<p><strong>Purpose: </strong>The menopausal transition is accompanied by metabolic changes in women. This study explores the Chinese visceral adiposity index (CVAI) as a potential indicator of menopausal status to aid in disease prevention.</p><p><strong>Patients and methods: </strong>A cohort of 404 premenopausal Chinese women aged 45 years and above, from the China Health and Retirement Longitudinal Study (CHARLS), was included. CVAI was calculated from the 2011 survey data, menopausal status was collected in the 2018 survey, representing a 7-year longitudinal follow-up. The cross-sectional study cohort from the National Health and Nutrition Examination Survey (NHANES) included 3577 women aged 40-60 with CVAI and self-reported menopausal status from 2003 to 2020. Logistic regression models were estimated the odds ratio (OR) of the menopause data and 95% confidence intervals (CIs).</p><p><strong>Results: </strong>In the CHARLS cohort, the adjusted OR for menopause in the fourth quartile of CVAI compared to the first quartile was 5.23 (95% CI: 1.59, 17.17; P for trend: 0.005). Additionally, a significant difference in the association between menopausal status and CVAI was found between rural and urban populations (P for interaction = 0.029). Moreover, in the NHANES cohort, the CVAI and the menopausal status were associated after adjustment (OR: 1.02, 95% CI: 1.002, 1.037, P: 0.029). In the stratified analysis, the association of CVAI with the status of menopause was observed among other ethnicities which including Asians (OR: 1.092, 95% CI: 1.012, 1.178, P: 0.025). Finally, a nomogram was developed to facilitate the clinical assessment of menopause based on the CVAI.</p><p><strong>Conclusion: </strong>The CVAI demonstrated a significant association with the odds of menopausal status in both Chinese and the US populations, suggesting its potential as a correlative marker for menopausal status, but the associational strength may vary by population.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1421-1436"},"PeriodicalIF":2.5,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aerobic Vaginitis Caused By <i>Streptococcus Β- Hemolyticus</i> and <i>Staphylococcus Epidermidis</i> in a 26-Year-Old Woman with a History of Frequent Antibiotics Administration.","authors":"Pati Aji Achdiat, Amalia Laksmi Saraswati, Yulisa Handayani, Rasmia Rowawi, Retno Hesty Maharani","doi":"10.2147/IJWH.S516616","DOIUrl":"10.2147/IJWH.S516616","url":null,"abstract":"<p><p>Aerobic vaginitis (AV) is a form of vaginitis caused by the presence of aerobic bacteria, primarily <i>group B Streptococcus, Escherichia coli, Enterococcus faecalis, Streptococcus viridans</i>, and <i>Staphylococcus epidermidis</i>. This condition is characterized by clinical signs of acute inflammation, including vaginal redness, burning, increased vaginal secretions with a pH of 5, sticky vaginal discharge, leukocyte infiltration, and vulvar pruritus, which is defined as itching and irritation, and commonly occurs in individuals between the age of 15-30 years and 31-45 years. The report presents a case of AV caused by <i>Streptococcus β-hemolyticus</i> and <i>Staphylococcus epidermidis</i> in a 26-year-old female patient at Hasan Sadikin Hospital, Bandung. The treatment process includes the administration of amoxicillin 500 mg three times daily for 14 days. The patient was unmarried, routinely performed vaginal douching with betel soap, and frequently used a panty liner. Subsequently, a history of frequent antibiotic use was reported, however, the specific names of previously administered antibiotics remain unknown, except for clindamycin, which is the only agent specifically recalled. The patient also had a history of high exposure to stressors and underwent a bacterial culture examination taken from the vaginal introitus, which showed the presence of <i>Streptococcus β-hemolyticus</i> and <i>Staphylococcus epidermidis</i>. This case highlights the significance of AV in the differential diagnosis of vaginal infections, especially in atypical patient populations, and emphasizes the need for appropriate diagnostic measures such as bacterial culture to guide effective treatment strategies.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1437-1444"},"PeriodicalIF":2.5,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Value of MRI for Pelvic Lymph Node Extracapsular Invasion in Early-Stage Endometrial Carcinoma.","authors":"Qiufang Bao, Liping Zheng, Linliang Hong","doi":"10.2147/IJWH.S511642","DOIUrl":"10.2147/IJWH.S511642","url":null,"abstract":"<p><strong>Objective: </strong>Endometrial cancer (EC) is the major female malignant tumor in developed countries. MRI is frequently applied in gynecologic malignancies. We probed the diagnostic value of MRI for pelvic lymph node extracapsular invasion (PLNEI) in early-stage EC patients.</p><p><strong>Methods: </strong>Totally 142 early-stage EC patients were retrospectively enrolled and divided into the PLNEI_negative/PLNEI_positive groups. Differences in MRI parameters [volume index (VI), total tumor volume (TTV), tumor volume ratio (TVR), mean apparent diffusion coefficient (ADC_mean)] were analyzed. Early-stage EC patients with PLNEI were categorized into the high/low VI, TTV, TVR, ADC_mean groups. The relationships of VI, TTV, TVR and ADC_mean with clinicopathological characteristics were analyzed. Independent influencing factors for PLNEI, and the diagnostic value of VI, TTV, TVR and ADC_mean for PLNEI were analyzed by logistic univariate/multivariate regression and receiver operating characteristic curve, with differences in areas under the curves compared by Delong test.</p><p><strong>Results: </strong>There were significant differences in the histological type, histological grade, myometrial invasion depth, LVSI positive detection, LVSI type, cervical involvement, and CA125 level between the two groups. The VI, TTV and TVR values were elevated and ADC_mean value was reduced in patients with PLNEI, which were associated with the clinicopathological characteristics of early-stage EC patients. The CA125 level, VI, TTV, TVR and ADC_mean were independent influencing factors for PLNEI, showing high diagnostic value for PLNEI.</p><p><strong>Conclusion: </strong>VI, TTV, TVR, and ADC_mean had high diagnostic value for PLNEI in early-stage EC patients. MRI was a good method to detect PLNEI in EC patients.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1409-1419"},"PeriodicalIF":2.5,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12094826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144119678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Coronary Syndrome: Considerations Regarding Pregnancy [Letter].","authors":"Kuilin Fei, Xiaoe Jiang, Jingrui Huang","doi":"10.2147/IJWH.S519669","DOIUrl":"10.2147/IJWH.S519669","url":null,"abstract":"","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1407-1408"},"PeriodicalIF":2.5,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12087788/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}