International Journal of Women's Health最新文献

{"title":"Cross-Sectional Study on the Correlation Between Vaginal Microecology and High-Risk Human Papillomavirus Infection: Establishment of a Clinical Prediction Model.","authors":"Hua-Mei Liu, Fan Zhang, Heng-Yun Cai, Yu-Mei Lv, Meng-Yuan Pi","doi":"10.2147/IJWH.S479836","DOIUrl":"10.2147/IJWH.S479836","url":null,"abstract":"<p><strong>Purpose: </strong>High-risk human papillomavirus (HR-HPV) is a significant risk factor for cervical precancerous lesions and cancer. This study aimed to investigate the relationship between vaginal microecology and HR-HPV infection and to evaluate the clinical applicability of vaginal microecology in predicting HR-HPV infection.</p><p><strong>Patients and methods: </strong>Overall, 2000 women with simultaneously detected vaginal discharge and cervical HPV were selected between March 2022 and March 2023, including 241 and 1759 cases in the HR-HPV positive and HPV negative groups, respectively.</p><p><strong>Results: </strong>No significant differences were found in age, vulvovaginal candidiasis, trichomonas vaginitis, and β-N-acetylglucosaminosidase between the two groups (P>0.05). Significant differences were observed in <i>Lactobacillus</i> deficiency, bacterial vaginitis (BV), aerobic vaginitis (AV), glucuronidase (GUS), sialidase (SNA), and leukocyte esterase (LE) between the two groups (P<0.05). In the multivariate logistic regression equation, <i>Lactobacillus</i> deficiency, BV, AV, SNA, LE, and GUS were risk factors for HR-HPV infection (P<0.05). Three prediction models, namely, logistic regression, decision tree, and random forest, were established to rank the importance of the predictors. BV ranked first among the three prediction models. The logistic regression model demonstrated the highest accuracy in predicting the risk of HR-HPV infection. The calibration curve of the logistic regression model showed a strong correlation between the predicted and actual probabilities, and decision curve analysis revealed that the prediction model had good clinical applicability.</p><p><strong>Conclusion: </strong>Overall, vaginal microecology imbalance was closely associated with cervical HR-HPV infection, particularly BV and AV. The logistic regression model for the risk of HR-HPV infection based on six predictive factors (BV, AV, LE, SNA, <i>Lactobacillus</i> deficiency, and GUS) had good accuracy and clinical applicability.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"16 ","pages":"1765-1774"},"PeriodicalIF":2.5,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142568014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Random Survival Forest Model for Predicting Residual and Recurrent High-Grade Cervical Intraepithelial Neoplasia in Premenopausal Women.","authors":"Furui Zhai, Shanshan Mu, Yinghui Song, Min Zhang, Cui Zhang, Ze Lv","doi":"10.2147/IJWH.S485515","DOIUrl":"10.2147/IJWH.S485515","url":null,"abstract":"<p><strong>Purpose: </strong>Loop electrosurgical excision procedure (LEEP) for high-grade cervical intraepithelial neoplasia (CIN) carries significant risks of recurrence and persistence. This study compares the efficacy of a random survival forest (RSF) model with that of a conventional Cox regression model for predicting residual and recurrent high-grade CIN in premenopausal women after LEEP.</p><p><strong>Methods: </strong>Data from 458 premenopausal women treated for CIN2/3 at our hospital between 2016 and 2020 were analyzed. The RSF model incorporated demographic, pathological, and treatment-related variables. Feature selection utilizing LASSO and three other algorithms was performed to enhance the RSF model, which was further compared to a Cox regression model. Model performance was assessed using area under the curve (AUC), out-of-bag (OOB) error rates, and SHAP values to interpret predictor importance.</p><p><strong>Results: </strong>The RSF model showed superior performance compared to the Cox regression model, with AUC values of 0.767-0.901 and peak predictive performance at 36 months post-LEEP. In contrast, the highest AUC achieved by Cox regression was 0.880. The RSF model also exhibited relatively lower OOB error rates, indicating better generalizability. Moreover, SHAP value analysis identified margin status and CIN severity as the most prominent predictors that directly affected risk predictions. Lastly, an online tool providing real-time predictions in clinical settings was successfully implemented using the RSF model.</p><p><strong>Conclusion: </strong>The RSF model outperformed the traditional Cox regression model in predicting residual and recurrent high-grade CIN risks post-LEEP. This model may be a more accurate clinical tool that facilitates improved personalized care and early interventions in gynecological oncology.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"16 ","pages":"1775-1787"},"PeriodicalIF":2.5,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11531712/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changing Indications for Cervical Cerclage Following the Introduction of Routine Ultrasound Surveillance of Cervical Length for Prediction and Prevention of Preterm Birth.","authors":"Hasan Rawashdeh, Aparna Ramachandran, Jenny M Yang, Gemma Blain, Jon Hyett","doi":"10.2147/IJWH.S477974","DOIUrl":"10.2147/IJWH.S477974","url":null,"abstract":"<p><strong>Background: </strong>Preterm birth (PTB) is associated with significant neonatal mortality and morbidity. Universal measurement of cervical length has been proposed as a screening tool to direct intervention to prevent PTB.</p><p><strong>Aim: </strong>To assess the impact of the introduction of sonographic mid-trimester cervical length screening on the use of cervical cerclage and PTB.</p><p><strong>Material and methods: </strong>A retrospective cohort study reviewed two groups of women who underwent cervical cerclage before and after the introduction of universal sonographic cervical length screening. Demographics and outcomes were compared using Student's <i>t</i> test, Fisher's Exact test and Kaplan-Meier analysis.</p><p><strong>Results: </strong>Following introduction of universal cervical length screening, the overall rate of cerclage increased from 2.5/1000 births to 6.0/1000 births (p < 0.01). There was a reduction in the proportion of sutures placed purely based on maternal history (50.0% to 30.4%; p < 0.001), while the proportion of sutures placed following ultrasound assessment increased in both high- (21.7 to 36.6%) and low-risk (11.7% to 30.4%) women (p < 0.001). The overall rate of PTB <37 weeks in women has a cerclage was 25.7% and was highest in women undergoing rescue cerclage (64.3%; p < 0.01). There was no difference in the rate of PTB between high- and low-risk women undergoing history- or ultrasound-indicated cerclage. Mean pregnancy length was most prolonged in low-risk women undergoing ultrasound-indicated cerclage, extending gestation from 33.9 to 38.3 weeks (p < 0.01).</p><p><strong>Conclusion: </strong>Universal cervical length screening results in an increase in the use of cerclage, specifically on the basis of the ultrasound findings. Women who were at low risk but then underwent ultrasound-indicated cerclage experienced most prolongation of pregnancy. Women who were at high risk but had a suture on the basis of ultrasound findings-indicated cerclage represent an alternative method of management with no significant difference in the gestational age of delivery.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"16 ","pages":"1755-1764"},"PeriodicalIF":2.5,"publicationDate":"2024-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11523940/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the Use of Breast Self-Examination (BSE) for Recognizing Breast Cancer Awareness Among Jordanian Students and Workers in Medical Fields.","authors":"Ammar A Oglat, Tala AbuKhalil, Hanan Hasan, Israa H Isawi, Ahmad A Oqlat, Hamad Yahia Abu Mhanna, Hanan Fawaz Akhdar","doi":"10.2147/IJWH.S485116","DOIUrl":"10.2147/IJWH.S485116","url":null,"abstract":"<p><strong>Background: </strong>Globally, breast cancer (BC) is the most commonly detected neoplasm in women. Breast self-examination (BSE) is an effective screening technique that enables women to learn about the composition of their breasts and assist in the early identification of any potential breast abnormalities.</p><p><strong>Objective: </strong>This study aimed to assess the degree of BSE knowledge and attention among Jordanian females who are students or professionals in medical disciplines.</p><p><strong>Methods: </strong>Participants' knowledge about BSE and related issues was assessed using a self-administered questionnaire. The study invites participation from all females aged 18 and above, through both an online and in-person survey. The study extended invitations to female university students in Jordan across academic levels I, II, III, IV, V, and VI. A scoring system was employed, and the statistical analyses were performed using IBM SPSS Statistics (Version 20.0).</p><p><strong>Results: </strong>The study had 946 female participants, with 98.41% of them being single. Low BSE practice was reported among 90.49% of the participants (n = 856) and this demonstrated a weak understanding of BC disease, including its possible risks, methods of detection, diagnosis, treatment, signs and symptoms, as well as knowledge about mammography and other related information. Only 27.27% (n = 258) of participants practice BSE once a month and on a regular basis.</p><p><strong>Conclusion: </strong>BC is considered the most prevalent malignant condition and the second largest cause of cancer-related deaths for women in Jordan. Screening strategies are essential for promptly identifying breast cancer and reducing the associated illness and death rates. It is recommended that women commence performing BSE starting at the age of 18. Furthermore, it is essential to incorporate a learning outcome in the cancer chapters that are directly relevant to the subject of BC and emphasize the significance of BSE for students pursuing a career in the medical area.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"16 ","pages":"1743-1753"},"PeriodicalIF":2.5,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11522006/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elevated MMP-9, Survivin, TGB1 and Downregulated Tissue Inhibitor of TIMP-1, Caspase-3 Activities are Independent of the Low Levels miR-183 in Endometriosis.","authors":"R Muharam, Anom Bowolaksono, Mila Maidarti, Ririn Rahmala Febri, Kresna Mutia, Pritta Ameilia Iffanolida, Muhammad Ikhsan, Kanadi Sumapraja, Gita Pratama, Achmad Kemal Harzif, Andon Hestiantoro, Budi Wiweko","doi":"10.2147/IJWH.S469864","DOIUrl":"10.2147/IJWH.S469864","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to measure the correlation between miR-183 and gene expression that regulates apoptosis and adhesion mechanism that may be linked to the pathogenesis of endometriosis.</p><p><strong>Patients and methods: </strong>Forty-four subjects, including 22 control subjects, participated in this study. We collected ectopic endometriosis and endometrial samples. For the control, the sample was taken from endometrial tissue through pipelle biopsy. RNA was extracted from all tissues using RNA mini kit, and the expression was assessed using quantitative-real time PCR. Relative mRNA and miRNA expression were presented using the formula of the Livak method. The data were statistically analyzed using GraphPad Prism 8.</p><p><strong>Results: </strong>The expression of Caspase-3, Survivin, Integrin β1 (ITGB1), matrix metalloproteinase-9 (MMP-9), and tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) (adhesion- and apoptosis-related gene) were calculated using the relative expression method. We found significant differences in Caspase-3, Survivin, ITGB1, MMP-9, and TIMP-1 expression between ectopic endometriosis tissues of women with endometriosis compared to healthy endometrium. MMP-9, Survivin, and ITGB1 was significantly increased in the endometriosis group, while Caspase-3, TIMP-1, and miR-183 were significantly reduced in the endometriosis group. No correlation was found between the expression level of miR-183 and Caspase3, Survivin, ITGB1, and Cadherin in both tissue types.</p><p><strong>Conclusion: </strong>Despite the difference in expression levels of miR-183 and associated adhesion- and apoptosis-related genes, there was no significant association between miR-183 with specific adhesion and apoptosis genes in endometriosis tissue.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"16 ","pages":"1733-1742"},"PeriodicalIF":2.5,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11513572/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142521923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Future of Cervical Cancer Screening.","authors":"Amelia Goldstein, Mallory Gersh, Gabriela Skovronsky, Chailee Moss","doi":"10.2147/IJWH.S474571","DOIUrl":"10.2147/IJWH.S474571","url":null,"abstract":"<p><strong>Purpose: </strong>Cervical cancer remains a significant health concern, particularly in developing countries, where it is a leading cause of cancer-related deaths among women. Innovative technologies have emerged to improve the efficiency, cost-effectiveness, and sensitivity of cervical cancer screening and treatment methods. This study aims to explore the various approaches for the detection and treatment of human papillomavirus (HPV), cervical dysplasia (CD), and cervical cancer, highlighting new technologies and updated screening strategies in developing areas.</p><p><strong>Patients and methods: </strong>A comprehensive literature search was conducted using PubMed to identify relevant publications on the subject of cervical cancer screening and HPV detection.</p><p><strong>Results: </strong>HPV infection and cervical cancer continue to pose significant global health challenges. Emerging technologies such as rapid, low-cost HPV testing combined with high-resolution digital colposcopy and artificial intelligence interpretation hold promise for efficient and sensitive screening. Advancements in HPV vaccine distribution, high-risk HPV screening, DNA methylation assays, dual-stain cytology, lab-on-chip assays, and deep learning technologies offer new avenues for improved detection and risk stratification.Research and innovations in detection and treatment methods are crucial for reducing the burden of these diseases worldwide.</p><p><strong>Conclusion: </strong>Screening for HPV and CD plays a pivotal role in reducing the risk of cervical cancer-related mortality. The development of novel technologies, along with efforts to enhance global health equity and integrate cervical cancer prevention with HIV screening and treatment programs, represent critical steps toward achieving comprehensive cervical cancer screening on a global scale.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"16 ","pages":"1715-1731"},"PeriodicalIF":2.5,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11512781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142500546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complete Hydatidiform Mole with Twin Live Fetuses in a Triplet Pregnancy: A Case Report and Literature Review.","authors":"Qiong Li, Cancan Zou, Linli Xie, Suzhen Ran, Yanlin Chen, Tianjing Yan","doi":"10.2147/IJWH.S484634","DOIUrl":"10.2147/IJWH.S484634","url":null,"abstract":"<p><strong>Introduction: </strong>The coexistence of a complete hydatidiform mole with twin live fetuses in a triplet pregnancy is an extremely rare condition with an unknown incidence.</p><p><strong>Case report: </strong>This report presents a case of a dichorionic diamniotic triplet pregnancy complicated by the coexistence of a complete hydatidiform mole and twin live fetuses. The pregnancy resulted in a preterm delivery at 30 weeks and 5 days of gestation, with both live fetuses surviving to date. During the pregnancy, the patient was diagnosed with pre-eclampsia and intrahepatic cholestasis. Post-delivery, she was found to have an invasive mole with lung metastases, which was ultimately successfully treated.</p><p><strong>Conclusion: </strong>This report highlights critical considerations for managing a multiple pregnancy complicated by a complete hydatidiform mole, alongside the associated potential complications. In light of the limited literature on the clinical management of this condition, our findings offer valuable insights into navigating the risks and optimizing patient outcomes.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"16 ","pages":"1701-1713"},"PeriodicalIF":2.5,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11513570/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142521915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revisiting Assisted Reproductive Technology (ART) - Related Psychological Symptom Clusters [Letter].","authors":"Huimin Du, Kexin Wang","doi":"10.2147/IJWH.S497038","DOIUrl":"10.2147/IJWH.S497038","url":null,"abstract":"","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"16 ","pages":"1699-1700"},"PeriodicalIF":2.5,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11512508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142500545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health of Saudi Women in the Post-Pandemic Era: <i>Candidiasis</i> Incidence and Post COVID-19 and COVID-19-Vaccination.","authors":"Sami A Alawfi","doi":"10.2147/IJWH.S472953","DOIUrl":"https://doi.org/10.2147/IJWH.S472953","url":null,"abstract":"<p><strong>Introduction: </strong>Candidiasis, commonly known as yeast infection, affects people worldwide due to the overgrowth of <i>Candida</i> species. Of several types, genital candidiasis, particularly vulvovaginal candidiasis (VVC), primarily caused by <i>C. albicans</i> is frequently observed in females of reproductive age. Candidiasis has also become a serious issue in the post-pandemic era, as it occurs as a secondary infection in COVID-19 patients during or after the course of viral illness. Therefore, this study investigated the incidence of <i>C. albicans</i> infections in women of reproductive age, and its relationship with the incidence of COVID-19 and vaccination in Saudi Arabia.</p><p><strong>Objective: </strong>Additionally, this study aimed to determine the awareness of women on candidiasis and its subsequent impact on the occurrence of infection. A survey-based quantitative study was conducted in which primary data were collected from participants using a self-reported questionnaire.</p><p><strong>Methods: </strong>A total of 200 women aged 18-45 were selected through random sampling. Apart from their sociodemographic characteristics, the history of COVID-19 incidence, COVID-19 vaccination, and candidiasis occurrences among respondents were recorded. Their level of awareness and knowledge of candidiasis, along with their perceptions of strategies for mitigating the risk of incidence, were also evaluated. The collected data were analysed using different statistical tools.</p><p><strong>Results: </strong>The findings of this study revealed a positive correlation between candidiasis, viral infection, and vaccination, regardless of the type and dosage of vaccine administered. Furthermore, both COVID-19 incidence and vaccination had a positive and significant impact on the occurrence of candidiasis among Saudi women.</p><p><strong>Conclusion: </strong>Despite certain limitations, this study has theoretical and managerial implications for improved management of candidiasis in the post-COVID era.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"16 ","pages":"1687-1697"},"PeriodicalIF":2.5,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11484768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benign Brenner Tumor Mixed with Mucinous Cystadenoma of the Left Ovary: Case Report and Literature Review, 2023.","authors":"Okbu Frezgi, Tiblets Tesfamichael, Khalid Hussein Farah, Hailemichael Gebremariam, Yasir D Wahaballa, Berhe Tesfai","doi":"10.2147/IJWH.S449117","DOIUrl":"https://doi.org/10.2147/IJWH.S449117","url":null,"abstract":"<p><p>Ovarian mucinous tumors mixed with Brenner tumors have rarely been reported. The coexistence of such epithelial tumors present histopathologic diagnostic difficulties. Here we report a 57-year-old postmenopausal woman who had experienced an abdominal distention and pain over a period of eight months. A physical examination revealed a grossly distended abdomen that reached the xiphoid process. A firm and mobile abdomino-pelvic mass with a smooth surface and a regular border was identified. Laboratory investigations showed a hemoglobin level of 13.54 g/dl and a serum cancer antigen 125 (CA125) of 97.3 U/mL. Trans abdominal ultrasonography revealed a massive complex mass originating from the left adnexa. A laparotomy was performed and a 10 kg left adnexal mass was removed intact. Histopathological analysis revealed mixed benign mucinous cystadenoma with a Brenner tumor of the left ovary. After surgery the patient showed marked clinical improvement, resumed her regular daily activities in three months and no recurrence has occurred during her long follow up. As the coexistence of these mixed tumors is not uncommon, a thorough pathologic evaluation is necessary and health professionals should be aware of the mixed occurrence of epithelial ovarian tumors.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"16 ","pages":"1671-1675"},"PeriodicalIF":2.5,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11471084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}