Hualan Lin, Meifang Shen, Dongbei Li, Qiuxia Sun, Liubing Lan
{"title":"The Correlation Between Fetal Wellbeing and Umbilical Doppler Parameters in Pregnant Women with Gestational Hypertension.","authors":"Hualan Lin, Meifang Shen, Dongbei Li, Qiuxia Sun, Liubing Lan","doi":"10.2147/IJWH.S514427","DOIUrl":"https://doi.org/10.2147/IJWH.S514427","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the role of umbilical cord blood flow parameters in evaluating intrauterine fetal hypoxia and fetal growth restriction in pregnant women with gestational hypertension.</p><p><strong>Methods: </strong>One hundred and nine patients with gestational hypertension admitted from January 2020 to December 2023 were enrolled in this study. The peak systolic velocity/end diastolic velocity (S/D), pulse index (PI) and resistance index (RI) of cord blood were measured by ultrasound. According to the S/D, 109 cases were divided into 62 cases in the control group (S/D < 3) and 47 cases in the observation group (S/D ≥ 3), and the prognosis of pregnant women and fetuses in the two groups were compared. The ROC curves were used to analyze the effects of different parameters of umbilical blood flow on intrauterine fetal hypoxia and fetal growth restriction in pregnant women with gestational hypertension.</p><p><strong>Results: </strong>The incidence of intrauterine fetal hypoxia, fetal growth restriction, cesarean section, and unresponsive type of non-irritation test was decreased in the control group compared with the observation group (<i>P</i> < 0.05). However, there was no statistical difference in the incidence of neonatal asphyxia between the two groups (P > 0.05). ROC curve analysis showed that cord blood flow RI of pregnant women with gestational hypertension had the highest sensitivity and AUC in predicting intrauterine fetal hypoxia and growth restriction, and PI had the highest specificity in predicting intrauterine fetal growth restriction. The specificity of S/D, PI and RI in predicting intrauterine hypoxia was consistent (all 80%).</p><p><strong>Conclusion: </strong>The different parameters of umbilical blood flow in hypertensive pregnant women during pregnancy provide a good assessment of intrauterine fetal condition and can be used as clinical indicators to predict poor prognosis of intrauterine fetal hypoxia and fetal growth restriction.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"1009-1018"},"PeriodicalIF":2.5,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994114/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Primary Malignant Melanoma of the Uterine Cervix with S100 (Protein Marker Seen in Women with Melanoma) Negative Status and Novel ATM Gene Mutation: Case Report and Literature Review.","authors":"Liang Wang","doi":"10.2147/IJWH.S499393","DOIUrl":"https://doi.org/10.2147/IJWH.S499393","url":null,"abstract":"<p><p>Malignant melanoma (MM) is a relatively common malignant tumor. It mostly occurs in the skin, uvea of the eye, oral cavity, esophagus and anus, etc. Primary melanoma of the uterine cervix is very rare, with only more than 100 cases reported worldwide so far. In this article, we report a 42-year-old patient with primary cervical malignant melanoma. This case recorded the patient's entire process from onset, surgery, progression, treatment, deterioration, and death. The patient began to seek medical treatment after the discovery of cervical vegetations and eventually died of brain metastasis. The patient was negative for S100 by immunohistochemistry and had a frameshift mutation in the Ataxia-telangiectasia mutated (ATM) gene by genetic testing. This has never been described in previous cases and is reported for the first time.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"983-999"},"PeriodicalIF":2.5,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11992989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of the Application Value of Low Molecular Weight Heparin Combined with Heparin in Patients with Chorionic Bump in Early Pregnancy.","authors":"Xu-Ting Peng, Zhu-Hua Cai, Jie Shen, Hai-Yan Zhu","doi":"10.2147/IJWH.S507845","DOIUrl":"https://doi.org/10.2147/IJWH.S507845","url":null,"abstract":"<p><strong>Objective: </strong>To explore the application value of low molecular weight heparin combined with heparin in patients with chorionic bump in early pregnancy.</p><p><strong>Methods: </strong>This retrospective study collected 86 cases of patients with early pregnancy complicated by chorionic bump treated in our hospital from January 2020 to February 2022. According to the treatment methods, the patients were divided into the combined treatment group (n=41) and the control group (n=45). Patients in the combined treatment group were treated with oral prednisone combined with low molecular weight heparin injection, while patients in the control group received no additional treatment. The changes and differences in chorionic size, serum hormone levels, and uterine artery blood flow parameters before treatment and at 1 month and 2 months after treatment were compared between the two groups. The pregnancy outcomes and adverse reaction rates were also analyzed.</p><p><strong>Results: </strong>At 1 month and 2 months after treatment, the average size of the chorionic bump in the combined treatment group was significantly smaller than before treatment and the control group (P<0.05). Two months after treatment, the average levels of E2, P, and LH in the combined treatment group were significantly higher, and the average FSH level was significantly lower than those before treatment and in the control group (P<0.05). At 1 month and 2 months after treatment, the average RI in the combined treatment group was significantly lower than before treatment and the control group, and although the average S/D ratio was higher than before treatment, it was still lower than that of the control group (P<0.05). The incidence of adverse pregnancy outcomes in the combined treatment group was significantly lower than that in the control group (χ²/P=5.469/0.019). There was no significant difference in the incidence of adverse reactions between the two groups (χ²/P=0.613/0.434).</p><p><strong>Conclusion: </strong>Prednisone combined with low molecular weight heparin can effectively reduce the size of the chorionic bump, improve uterine artery blood flow parameters, and ultimately lower the risk of adverse pregnancy outcomes in patients with early pregnancy complicated by chorionic bump. This treatment approach has reliable clinical safety and holds potential for broader application in such patients.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"973-982"},"PeriodicalIF":2.5,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11988196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144023751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Umbilical Vessel Rupture Leading to Adverse Pregnancy Outcomes: Two Cases.","authors":"MeiRong He, KaiSun Zhao, JianChun Huang","doi":"10.2147/IJWH.S510550","DOIUrl":"https://doi.org/10.2147/IJWH.S510550","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to alert authors and readers to the possibility of spontaneous umbilical vessel rupture in cases of sudden changes in fetal heart rate or bloody amniotic fluid.</p><p><strong>Methods: </strong>We analyzed cases of spontaneous rupture of umbilical cord vessels at our hospital over the past three years. Two cases of patients who delivered at our hospital were analyzed, both of whom exhibited sudden changes in fetal heart rate during the prenatal period and subsequently underwent emergency cesarean sections. Intraoperatively, both cases revealed a succenturiate placenta with ruptured umbilical vessels and bleeding.</p><p><strong>Results: </strong>Both cases resulted in adverse pregnancy outcomes due to succenturiate placenta and bleeding from ruptured umbilical vessels, with pathological examination of the placenta confirming the clinical diagnosis.</p><p><strong>Conclusion: </strong>Enhancing the detection rate of prenatal ultrasound for placental membranacea and umbilical cord vessel abnormalities, coupled with timely intervention, is crucial for reducing perinatal mortality.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"965-971"},"PeriodicalIF":2.5,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11981871/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Monica Dwi Hartanti, Rahmi Amtha, Raditya Wratsangka, Astri Rinanti, Endang Djuana, Ilham Hizbulloh, Christopher Andrew Teguh, Alvionita Kogoya, Didik T Subekti, Muhammad Ibrahim Desem, Christina Safira Whinie Lestari, Talitha Asmaria
{"title":"Operational Feasibility and Performance of mRPA Versus PCR for the Detection of HPV Types 16, 18, and 52 in Clinical Samples: An Exploratory Study.","authors":"Monica Dwi Hartanti, Rahmi Amtha, Raditya Wratsangka, Astri Rinanti, Endang Djuana, Ilham Hizbulloh, Christopher Andrew Teguh, Alvionita Kogoya, Didik T Subekti, Muhammad Ibrahim Desem, Christina Safira Whinie Lestari, Talitha Asmaria","doi":"10.2147/IJWH.S496621","DOIUrl":"https://doi.org/10.2147/IJWH.S496621","url":null,"abstract":"<p><strong>Purpose: </strong>This exploratory study investigates the feasibility and performance of multiplex Recombinase Polymerase Amplification (mRPA) compared to conventional Polymerase Chain Reaction (PCR) for the detection and genotyping of high-risk Human Papillomavirus (HPV) types 16, 18, and 52. Current PCR methods are widely used for HPV detection but are limited by the need for complex thermal cycling equipment and lengthy processing times, which restrict their use in low-resource settings. This study aims to evaluate whether mRPA can serve as a faster, simpler, and more accessible alternative for HPV screening in primary healthcare environments.</p><p><strong>Methods: </strong>A total of 20 clinical samples from cervical swabs were tested using both mRPA and conventional PCR. The samples were preserved in ThinPrep<sup>®</sup> Specimen Collection fluid and stored at -20°C. mRPA reactions were conducted under isothermal conditions at 39°C for 30 minutes, while conventional PCR followed standard cycling protocols. Sensitivity, specificity, operational efficiency, and feasibility in low-resource settings were assessed and compared between the two methods. The study complies with the Declaration of Helsinki and was approved by the Ethics Committee of Faculty of Medicine, Universitas Indonesia.</p><p><strong>Results: </strong>The mRPA demonstrated sensitivity and specificity that were lower than PCR, with detection rates of 100% for HPV 16, 80% for HPV 18, and 60% for HPV 52, compared to PCR's 100% across all types. Overall, mRPA achieved an overall sensitivity of 80% and specificity of 100%. However, mRPA significantly reduced the amplification time to 30 minutes and eliminated the need for thermal cyclers, highlighting its potential suitability for primary healthcare settings. The practical implications of mRPA's rapid turnaround time and simplified equipment requirements make it a promising tool for point-of-care applications in resource-limited environments.</p><p><strong>Conclusion: </strong>The findings suggest that mRPA could serve as a viable alternative to conventional PCR for HPV genotyping, offering advantages in speed and simplicity. Although mRPA's diagnostic performance was lower than PCR, its operational benefits make it particularly suitable for use in resource-limited settings. Future research should focus on further optimization and validation to enhance mRPA's diagnostic accuracy and explore its integration with user-friendly detection platforms.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"955-964"},"PeriodicalIF":2.5,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11980794/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144011390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chun Lan Yuan, Mei Rong He, Shi Mei He, Jian Chun Huang, Wen Qian Jian, Kai Sun Zhao
{"title":"Differences in Pregnancy Outcomes Between in vitro Fertilization and Natural Conception in Nulliparous Singleton Pregnancies of Advanced Maternal Age: A Study Based on Propensity Score Matching and Cohort Retrospective Analysis.","authors":"Chun Lan Yuan, Mei Rong He, Shi Mei He, Jian Chun Huang, Wen Qian Jian, Kai Sun Zhao","doi":"10.2147/IJWH.S510393","DOIUrl":"https://doi.org/10.2147/IJWH.S510393","url":null,"abstract":"<p><strong>Objective: </strong>To compare pregnancy outcomes between in vitro fertilization (IVF) and natural conception in singleton pregnancies among nulliparous of advanced maternal age.</p><p><strong>Patients and methods: </strong>This retrospective analysis utilized propensity score matching (PSM) on 128 cases in the IVF group and 196 cases in the natural conception group, selected from the Second Nanning People's Hospital between January 2020 and December 2023. Early and late pregnancy outcomes assessed included hemoglobin (Hb) levels, oligohydramnios, fetal growth restriction (FGR), gestational diabetes mellitus (GDM), hypertensive disorders of pregnancy (HDP), placenta previa, placental abruption, premature rupture of membranes, fetal distress, mode of delivery, gestational age at delivery, preterm birth, low birth weight, macrosomia, and blood loss during delivery.</p><p><strong>Results: </strong>The IVF group exhibited a higher incidence of oligohydramnios and a lower incidence of low birth weight compared to the natural conception group, with both differences being statistically significant (P < 0.05). No significant differences were found between the two groups for other pregnancy complications.</p><p><strong>Conclusion: </strong>Pregnancy outcomes for IVF and natural conception are comparable in singleton pregnancies among nulliparous of advanced maternal age. However, clinicians should remain vigilant regarding the risks of oligohydramnios and low birth weight in IVF pregnancies to ensure appropriate monitoring and intervention.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"947-954"},"PeriodicalIF":2.5,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11980792/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Docosahexaenoic acid (DHA) Supplementation During Pregnancy Reduces the Risk of Preterm Birth in Threatened Preterm Labor. The Multicenter Randomized Controlled Trial.","authors":"Wiphawi Phattharachindanuwong, Sukanya Chaiyarach, Ratana Komwilaisak, Piyamas Saksiriwuttho, Chatuporn Duangkum, Kiattisak Kongwattanakul, Pilaiwan Kleebkaow, Termtem Waidee, Manasicha Pongsamakthai, Sathida Chantanavilai, Tunyatorn Srisataporn","doi":"10.2147/IJWH.S518312","DOIUrl":"10.2147/IJWH.S518312","url":null,"abstract":"<p><strong>Background: </strong>Threatened preterm labor is a common reason for hospital admission, and DHA supplementation may lower the risk of preterm labor.</p><p><strong>Objective: </strong>To compare the rates of premature birth between individuals with threatened preterm labor who received DHA and those who did not.</p><p><strong>Methods: </strong>In this multi-center randomized controlled trial, the sample size was calculated to be 60 participants. Pregnant individuals who experienced threatened preterm labor at 24 to 34 weeks gestation were given either 1000 milligrams of DHA daily or no DHA supplement. The criteria for inclusion consisted of singleton pregnancies that had been diagnosed with threatened preterm labor, with no cervical change present. DHA supplementation was initiated when threatened preterm labor was diagnosed and continued until 37 weeks of gestation or until delivery, whichever occurred first. The main outcome was to compare the rates of premature births between the two groups. Moreover, we intended to evaluate the side effects of the DHA supplement along with the outcomes for neonates.</p><p><strong>Results: </strong>Sixty-one pregnant individuals were enrolled and randomly assigned to two groups. Group 1 consisted of 30 participants, each receiving a daily intake of 1,000 milligrams of DHA supplement. Group 2, comprising 31 individuals, did not receive any supplemental DHA. The rate of preterm birth was 23.33% (7/30) and 25.81% (8/31) for the participant group receiving DHA and not receiving DHA, respectively, with a p-value of 0.82. The rate of low-birth-weight neonates was 13.33% (4/30) and 19.35% (6/31) for the participant group receiving DHA and not receiving DHA, respectively, with a p-value of 0.73. The overall results did not show any statistically significant differences. In addition, the rates of cesarean sections, peripartum infections, early postpartum hemorrhage, and NICU admissions did not show significant differences between the two groups.</p><p><strong>Conclusion: </strong>Taking DHA supplements after a diagnosis of threatened preterm pregnancy does not decrease the actual rates of early or late preterm births. To reduce the risk of premature birth, DHA should be taken from the beginning of pregnancy, with a recommendation to start in the first trimester. This should ideally start in the second trimester, no later than around 20 weeks of gestation, and should continue until childbirth or approximately 37 weeks of gestation.</p><p><strong>Clinical trial registration: </strong>https://register.clinicaltrials.gov/.</p><p><strong>Clinical trials: </strong>gov; ID: NCT06302023.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"937-945"},"PeriodicalIF":2.5,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967355/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143779482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yizheng Zu, Yi Xie, Huale Zhang, Lichun Chen, Shihan Yan, Zhenna Wang, Zhuanji Fang, Shunhe Lin, Jianying Yan
{"title":"Endometriosis Severity and Risk of Preeclampsia: A Combined Mendelian Randomization and Observational Study.","authors":"Yizheng Zu, Yi Xie, Huale Zhang, Lichun Chen, Shihan Yan, Zhenna Wang, Zhuanji Fang, Shunhe Lin, Jianying Yan","doi":"10.2147/IJWH.S508174","DOIUrl":"10.2147/IJWH.S508174","url":null,"abstract":"<p><strong>Purpose: </strong>Endometriosis has been hypothesized to increase the risk of preeclampsia (PE) and eclampsia, although the exact mechanism of this relationship is not clear. This study aimed to further explore the potential association between endometriosis and PE/eclampsia through Mendelian randomization (MR) and confirm these findings in a retrospective cohort study.</p><p><strong>Methods: </strong>A two-sample MR study was performed using genetic variants associated with endometriosis from the Finnish database, with outcome data for PE and eclampsia from the UK Biobank. Subgroup analyses were conducted based on endometriosis severity (American society of reproductive Medicine (ASRM) stages I-II and III-IV) and anatomical location (uterus, ovary, deep infiltrating endometriosis). Additionally, a retrospective cohort study was conducted to further assess the association, adjusting for confounding factors such as age, Body Mass Index (BMI), dysmenorrhea, history of uterine surgery, and adenomyosis. Multivariate logistic regression was used to analyze the risk of PE/eclampsia based on endometriosis severity.</p><p><strong>Results: </strong>MR using the Inverse Variance Weighted method found a meaningful association between advanced endometriosis (ASRM stages III-IV) and PE/eclampsia (p = 0.008), while no significant associations were observed for lower stages or endometriosis in the uterus and ovary. In the retrospective cohort, the initial association between the revised American Fertility Society (r-AFS) score and PE/eclampsia (OR: 1.02, 95% CI: 1.01-1.03, p < 0.001) weakened after adjusting for confounders. Significant risk factors identified included age (OR: 1.20, 95% CI: 1.10-1.30, p < 0.001), dysmenorrhea (OR: 2.72, 95% CI: 1.31-5.76, p = 0.008) and adenomyosis showing the strongest association (OR: 9.96, 95% CI: 5.00-20.06, p < 0.001).</p><p><strong>Conclusion: </strong>The findings suggest a potential relationship between advanced endometriosis and the risk of PE/eclampsia. However, other clinical factors such as age, dysmenorrhea, and adenomyosis appear to contribute more significantly to the risk. Further studies are needed to confirm these findings and clarify the underlying mechanisms.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"923-935"},"PeriodicalIF":2.5,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11956705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anwar M Alhashem, Fay A Alrasheed, Latifa K Alwallan, Maram F Almutairi, Yara M Bin Khathran, Yasmeen A Alenzi, Rehab A Aldahash
{"title":"Traditional Nutritional Beliefs and Practices Among Mothers in Riyadh During the Puerperal Period: a Cross-Sectional Study.","authors":"Anwar M Alhashem, Fay A Alrasheed, Latifa K Alwallan, Maram F Almutairi, Yara M Bin Khathran, Yasmeen A Alenzi, Rehab A Aldahash","doi":"10.2147/IJWH.S484271","DOIUrl":"10.2147/IJWH.S484271","url":null,"abstract":"<p><strong>Purpose: </strong>During the postpartum period, women undergo physical, social, and emotional changes, with misconceptions regarding postpartum nutrition resulting in high neonatal mortality rates. Traditional nutritional beliefs and practices during pregnancy, childbirth, and postnatal care differ among cultures. We assessed nutritional beliefs and practices among mothers during the puerperal period.</p><p><strong>Patients and methods: </strong>This descriptive cross-sectional study was conducted from October 2021 to April 2022 using an online survey questionnaire regarding beliefs and practices on nutrition during the puerperal period with a sample of 381 mothers. Descriptive statistics were used to report sociodemographic characteristics and nutritional beliefs and practices. ANOVA and two-sample independent <i>t</i>-test were used to analyze nutritional practices by sociodemographic factors. Simple linear regression was used to predict age-based nutritional beliefs and practices. Pearson correlation was used to compare nutritional beliefs and practices.</p><p><strong>Results: </strong>Mothers did not avoid food and water after normal delivery. Many preferred Arabic coffee and peel. Age predicted the total scores of nutritional beliefs and practices, with a positive correlation between nutritional beliefs and practices. New mothers followed certain nutritional customs, such as consuming herbs postpartum. Mothers who had only completed high school or less obtained higher scores on nutritional belief evaluations, and those with ≥5 children displayed a greater number of nutritional beliefs. Those who delivered their first and second children naturally prioritized their dietary habits more than those who had a cesarean delivery.</p><p><strong>Conclusion: </strong>The findings suggest complex relationships among various factors and postpartum dietary choices.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"913-922"},"PeriodicalIF":2.5,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11955736/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Catherine Atuhaire, Kabanda Taseera, Daniel Atwine, Samuel Maling, Vikram Patel
{"title":"Prevalence and Factors Associated With Antepartum Depression Among Pregnant Women in Latent Labor: A Multi-Facility Cross-Sectional Study in Rural Southwestern Uganda.","authors":"Catherine Atuhaire, Kabanda Taseera, Daniel Atwine, Samuel Maling, Vikram Patel","doi":"10.2147/IJWH.S508301","DOIUrl":"10.2147/IJWH.S508301","url":null,"abstract":"<p><strong>Background: </strong>Despite limited studies on antepartum depression (APD) in Sub-Saharan Africa (SSA), it is suggested that the prevalence on the continent may be higher than the global average. This study aimed at determining the prevalence of APD and identifying its associated factors among pregnant women in latent labor in rural south western Uganda.</p><p><strong>Methods: </strong>The findings in this manuscript were part of a prospective cohort that aimed at investigating Social Support and Perinatal Depression among women in latent labor through six weeks postpartum. We conducted a multi-facility study enrolling women in latent labor to assess for APD and its associated factors from November 2023 to March 2024. The study was carried out in three health facilities in Mbarara District, rural southwestern Uganda. The prevalence of APD based on the Mini International Psychiatric Interview (M.I.N.I 7.0.2) using the depression module. Factors associated with APD were analyzed using bivariate and multivariate logistic regression. Variables with a p-value <0.2 in bivariate analysis were included in the multivariable model, with statistical significance set at p<0.05. Odds ratios (OR) and 95% confidence intervals (CI) were reported. Data were analyzed using STATA software version 14.0.</p><p><strong>Results: </strong>Of the 448 enrolled participants, 37 had APD giving a prevalence of 8.2% (95% CI: 6.0-11.2%). Factors that were significantly associated with APD were Maternal age 30-49 years, bad health status before pregnancy, not happy about being pregnant, having had complications during pregnancy and having a history of stressful life events during pregnancy.</p><p><strong>Conclusion: </strong>This study reveals a very significant yet comparatively lower prevalence of antepartum depression among pregnant women in latent labor in rural southwestern Uganda. These insights highlight the persistent need for comprehensive mental health strategies especially the non-pharmacological approaches within antenatal care to enhance maternal and child health outcomes.</p>","PeriodicalId":14356,"journal":{"name":"International Journal of Women's Health","volume":"17 ","pages":"903-912"},"PeriodicalIF":2.5,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11954394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}