International Medical Case Reports Journal最新文献_第9页

Plasmodium Vivax as a Causative Agent for Cerebral Malaria in a Group of Adults at Mizan Tepi Teaching Hospital: Case Series. 米赞特皮教学医院一组成人的脑疟疾病原体--间日疟原虫：病例系列。

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International Medical Case Reports Journal Pub Date : 2024-03-13 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S440800

Yosef Habtemariam, Molla Asnake, Misikr Alemu, Erkyehun Pawlos Shash, Tsegaw Worku Tessema, Zerubabel Girma Tesso, Michael Hawlet

{"title":"Plasmodium Vivax as a Causative Agent for Cerebral Malaria in a Group of Adults at Mizan Tepi Teaching Hospital: Case Series.","authors":"Yosef Habtemariam, Molla Asnake, Misikr Alemu, Erkyehun Pawlos Shash, Tsegaw Worku Tessema, Zerubabel Girma Tesso, Michael Hawlet","doi":"10.2147/IMCRJ.S440800","DOIUrl":"https://doi.org/10.2147/IMCRJ.S440800","url":null,"abstract":"In 2022, there were 249 million cases of malaria globally, resulting in 608,000 deaths. The majority of cases and deaths occurred in the WHO (World Health Organization) African Region. A study in our region found that, out of 263,476 individuals, 148,734 had P. falciparum, 106,946 had P. vivax, and 7,796 had mixed infections. The prevalence of P. falciparum (Plasmodium falciparum) was 8.97% and P. vivax (Plasmodium Vivax) was 7.94%. Although there have been a few reported cases of cerebral malaria caused by P. vivax, there is currently no comprehensive analysis of such cases. All the cases that have been reported so far involved individuals living in malaria-endemic areas, who presented with symptoms characteristic of cerebral malaria. Cerebral malaria was diagnosed based on the clinical algorithm which WHO used except we used P. vivax instead of P. falciparum The diagnosis of these cases was confirmed through thin blood film examination and Rapid Diagnostic Tests (RDTs). Therefore, this report aims to provide additional data on the occurrence of P. vivax as a cause of cerebral malaria. It also recommends further studies to reassess the current clinical case definition of cerebral malaria mainly in endemic areas as it affects patient treatment outcome.","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10949269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140174649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilateral Iris Coloboma in an 11-Year-Old Child with Low Vision and High Intraocular Pressure: A Rare Case Report and Review of Literature. 一名 11 岁低视力和高眼压儿童的双侧虹膜体瘤：罕见病例报告和文献综述。

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International Medical Case Reports Journal Pub Date : 2024-03-12 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S453954

Tawfiq Ahmad Mushkani, Zabih Ur Rahman Roheen

{"title":"Bilateral Iris Coloboma in an 11-Year-Old Child with Low Vision and High Intraocular Pressure: A Rare Case Report and Review of Literature.","authors":"Tawfiq Ahmad Mushkani, Zabih Ur Rahman Roheen","doi":"10.2147/IMCRJ.S453954","DOIUrl":"10.2147/IMCRJ.S453954","url":null,"abstract":"Background: Coloboma means curtailed in Greek language. It is mainly used when normal tissue of the eye or another organ is not present since birth. Coloboma is a congenital abnormality mainly caused by incomplete closure of the embryonic fissure of the choroid part of eye.Purpose: The aim of this case report is to share the clinical findings in a patient with bilateral iris coloboma, low vision, and headache.Patients and methods: Case report.Results: An eleven-year-old boy with low vision and headache visited the University Eye Hospital of Kabul University of Medical Science (UEHKUMS) for consultation. Ophthalmic examination revealed a bilateral iris coloboma without concomitant chorioretinal defect, refractive error, and high intraocular pressure in both eyes. The refractive error of the patient was corrected by advising proper glasses, and the high intraocular pressure was controlled by anti-glaucoma drops. After several follow-up visits, the patient no longer complained of headache and low vision.Conclusion: Visiting patients with iris coloboma should be considered for intraocular pressure (IOP) check, and screening of other family members is mandatory.","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10944301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140143427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case Series: A Mother and Daughter with a Critically Low Hemoglobin Level Resulting from Severe Anemia Secondary to Malaria. 病例系列：一对因疟疾引起严重贫血而导致血红蛋白水平极低的母女。

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International Medical Case Reports Journal Pub Date : 2024-03-11 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S448712

Dano Gutata

{"title":"A Case Series: A Mother and Daughter with a Critically Low Hemoglobin Level Resulting from Severe Anemia Secondary to Malaria.","authors":"Dano Gutata","doi":"10.2147/IMCRJ.S448712","DOIUrl":"10.2147/IMCRJ.S448712","url":null,"abstract":"Background: Malaria can lead to anemia, a condition marked by a reduction in red blood cells or lower than typical levels of hemoglobin. This condition mainly affects women and children and, in severe cases, can hinder the cognitive and motor development of children. It also poses significant risks for pregnant women and their unborn children.Case presentation: An 18-month-old girl and her mother, referred from conflict-affected West Wollega, Ethiopia due to severe malaria, were admitted to Assosa General Hospital, Ethiopia, with critical health indicators. The daughter (case 1) had a hemoglobin level of 0.8 g/dL, a red blood cell count of 0.44 × 10^6u/L, an oxygen saturation of 90%, a body temperature of 36.6 °C, a heartbeat of 132 beats per minute, and a respiratory rate of 48 breaths per minute. She displayed signs of pale conjunctivitis and severe palmar paleness, and weighed 7 kg. The mother(case 2), aged 35, also had a history of severe malaria and presented with a critically low hemoglobin level of 2.5g/dL and a red blood cell count of 0.75 × 10^6u/L, with an oxygen saturation of 89%. Blood transfusion and malaria treatment were administered, and by the end of their hospital stay, both cases' symptoms had resolved, and they returned to normal baseline vital signs, including their hemoglobin levels.Conclusions: Severely low hemoglobin levels, worsened by severe malaria, present a significant danger in cases of anemia. As far as I am aware, this might be the lowest hemoglobin level recorded. Promoting awareness, economic empowerment initiatives, alongside routine provision of iron supplements and Prompt malaria diagnosis and treatment to create a comprehensive approach that addresses the multifaceted challenges posed by anemia, ultimately leading to improved health outcomes for vulnerable populations.","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10941984/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140143426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rare Manifestation of Secondary Hyperparathyroidism Due to Brown Tumors: A Case Report. 棕色肿瘤导致的继发性甲状旁腺功能亢进症的罕见表现：病例报告

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International Medical Case Reports Journal Pub Date : 2024-02-26 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S437191

Maria Boudina, Eleana Zisimopoulou, Pantelitsa Rakitzi, Sotirios Barbanis, Eleni Syndouka, Chrysanthi Zouli, Aimilia Fotiadou, Mariana Stamati Stamati, Chrysanthi Balodimou, George Christantoniou, Alexandra Chrisoulidou

引用次数: 0

Clozapine-Induced Severe Toxicity: Exploring the Pharmacokinetic Profile of Clozapine and Its Significance in Hemodynamic Instability - A Case Report. 氯氮平诱发的严重毒性：探索氯氮平的药代动力学特征及其在血流动力学不稳定性中的意义--病例报告。

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International Medical Case Reports Journal Pub Date : 2024-02-08 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S444685

Zhu-Xi Yu, Yang Pi, Mei-Kai Chen, Dan-Jiang Dong, Qin Gu

引用次数: 0

Trifluridine and Tipiracil Hydrochloride Combination-Induced Interstitial Pneumonia: A Case Report. 曲氟尿苷和盐酸替吡西尔复方制剂诱发的间质性肺炎：病例报告。

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International Medical Case Reports Journal Pub Date : 2024-02-07 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S444330

Shun Nakazawa, Motoyasu Kato, Yuriko Terayama, Naho Sakamoto Matubara, Yoshihiko Sato, Ryoko Murashima, Daisuke Hayakawa, Shouichi Okamoto, Kazuhisa Takahashi

{"title":"Trifluridine and Tipiracil Hydrochloride Combination-Induced Interstitial Pneumonia: A Case Report.","authors":"Shun Nakazawa, Motoyasu Kato, Yuriko Terayama, Naho Sakamoto Matubara, Yoshihiko Sato, Ryoko Murashima, Daisuke Hayakawa, Shouichi Okamoto, Kazuhisa Takahashi","doi":"10.2147/IMCRJ.S444330","DOIUrl":"https://doi.org/10.2147/IMCRJ.S444330","url":null,"abstract":"We report a case of a 62-year-old male who was diagnosed with advanced rectal cancer. The attending gastro-enterologist initiated chemotherapy using capecitabine plus oxaliplatin and bevacizumab; however, this treatment regimen was discontinued, as the patient developed a skin rash. Once the skin rash improved, chemotherapy was re-initiated using a combination of trifluridine and tipiracil hydrochloride (TAS-102). The patient developed high fever and dyspnea 2 months after initiation of TAS-102. Chest high-resolution computed tomography showed bilateral diffuse ground glass opacities in all lung lobes with traction bronchiectasis. At this time, the gastro-enterologist consulted our department. The patient was put on non-invasive positive pressure ventilation due to worsening respiratory symptoms. The patient was suspected to develop TAS-102-induced interstitial pneumonia based on positive TAS-102 drug-induced lymphocyte stimulation test. The patient's respiratory symptoms and radiological findings improved after corticosteroid treatment. The corticosteroid dose was gradually decreased by 5 mg. Thereafter, chemotherapy was re-initiated using different anti-cancer agents.","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10859052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139722503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Young Woman with Fulminant Myocarditis with Cardiogenic Shock - Management with Assist Devices: A Case Report. 一名年轻女性患急性心肌炎并发心源性休克--辅助设备治疗：病例报告。

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International Medical Case Reports Journal Pub Date : 2024-02-07 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S440590

Feng Hu, Ben Luo, Xun Yuan, Linlin Zhang, Lianglong Chen

{"title":"A Young Woman with Fulminant Myocarditis with Cardiogenic Shock - Management with Assist Devices: A Case Report.","authors":"Feng Hu, Ben Luo, Xun Yuan, Linlin Zhang, Lianglong Chen","doi":"10.2147/IMCRJ.S440590","DOIUrl":"https://doi.org/10.2147/IMCRJ.S440590","url":null,"abstract":"Background: Severe heart failure or cardiogenic shock might arise as a consequence of fulminant myocarditis if it manifests and advances swiftly. The effective implementation of an immunological modulation regimen and mechanical circulatory support has proven instrumental in preserving the lives of individuals experiencing hemodynamic disturbance.Case presentation: The current report described a severe instance of fulminant myocarditis in an 18-year-old young woman who presented with severe hypoxemia and hemodynamic instability. The patient was treated with a combination of optimal medical therapy, immunological modulation, extracorporeal membrane oxygenation (ECMO), and an intra-aortic balloon pump (IABP) to support him through his critical period of hemodynamic collapse.Conclusion: The case presented herein underscored the prompt reversal of life-threatening fulminant myocarditis subsequent to a comprehensive treatment regimen encompassing optimal medical therapy and aggressive mechanical circulatory support.","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10859050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139722500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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A Case Report of Varicella Zoster Virus Infection Progressing to Necrotizing Fasciitis in an Immunocompetent Adult. 一例免疫功能健全的成人水痘带状疱疹病毒感染进展为坏死性筋膜炎的病例报告。

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International Medical Case Reports Journal Pub Date : 2024-02-07 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S421248

Ahmed Mohamed Ali, Edip Bayrak, Abdirahman Ahmed Mohamud, Zakaria Kasim Ali

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Primary Intra-Orbital Hydatid Cyst: A Case Report of a Rare Cause of Exophthalmos. 原发性眶内囊水瘤：眼球外翻罕见病因的病例报告。

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International Medical Case Reports Journal Pub Date : 2024-02-05 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S454518

Asrat Sime Debela, Kibruyisfaw Weldeab Abore, Alemayehu Bedane Worke, Selamawit Tadesse Wendimagegn

{"title":"Primary Intra-Orbital Hydatid Cyst: A Case Report of a Rare Cause of Exophthalmos.","authors":"Asrat Sime Debela, Kibruyisfaw Weldeab Abore, Alemayehu Bedane Worke, Selamawit Tadesse Wendimagegn","doi":"10.2147/IMCRJ.S454518","DOIUrl":"https://doi.org/10.2147/IMCRJ.S454518","url":null,"abstract":"Background: Hydatid disease is a tapeworm parasitic infection caused by Echinococcus granulosus that commonly affects the liver and lungs during its life cycle in the human body. Orbital involvement is a very rare occurrence and isolated orbital Echinococcosis is extremely rare.Case presentation: A 60-year-old female Eritrean woman presented with 3-month history of painless protrusion of the left eye. Physical examination showed significantly decreased visual acuity of the left eye, left eye proptosis, and papilledema. Laboratory investigations were normal and orbital CT scan examination was suggestive of orbital hydatid cyst. After giving two weeks course of oral Albendazole, anterior orbitotomy and cyst excision was done. Post-op biopsy was conclusive of orbital hydatid cyst. She had mild lid swelling and adduction deficit on her post-operative follow-up. Subsequent longer duration of follow-up of the patient was not possible since the patient relocated back to Eritrea.Conclusion: Orbital hydatid cyst is an extremely rare presentation of human Echinococcus granulosus infection. However, it should be considered one of the differential diagnoses among patients living in an endemic area and presenting with proptosis of the eye. A preoperative course of anthelmintic followed by surgical excision of the cyst is the definitive management.","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10854397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139722502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case Report: Optic Disc Melanocytoma with PHOMS—Minimum Intensity Projection Image 病例报告：带有 PHOMS-Minimum Intensity 投影图像的视盘黑色素细胞瘤

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International Medical Case Reports Journal Pub Date : 2024-02-01 DOI: 10.2147/IMCRJ.S444050

Fubin Wang

{"title":"Case Report: Optic Disc Melanocytoma with PHOMS—Minimum Intensity Projection Image","authors":"Fubin Wang","doi":"10.2147/IMCRJ.S444050","DOIUrl":"https://doi.org/10.2147/IMCRJ.S444050","url":null,"abstract":"Introduction Optic disc melanocytoma (ODMC) with peripapillary hyperreflective ovoid mass-like structures (PHOMS) is rare. This study reports a case of the characteristics of multimodal imaging and Minimum intensity projection (Min-IP) images. Methods A 25-year-old male patient was referred to our hospital due to the presence of a dark pigmented tumor located in the optic disc area of his left eye. The patient exhibited normal pupillary reactions and had a best corrected visual acuity of 1.0 (decimal) in both eyes. This patient underwent multimodal retinal imaging examination including color fundus photograph (CFP), B-scan ultrasonography, Fundus autofluorescence (FAF), SD-OCT (spectral-domain optical coherence tomography), OCTA (optical coherence tomography angiography), en-face Min-IP image and fluorescein angiography (FA). Results CFP revealed a slightly elevated mass lesion in the inferior quadrant of the left optic disc, the lesion appeared black to dark brown in color. B-scan ultrasonography of the left eye confirmed the presence of a hyperechoic small dome-shaped lesion. Fundus autofluorescence (FAF) analysis revealed complete hypofluorescence in this area. SD-OCT (spectral-domain optical coherence tomography) and OCTA (optical coherence tomography angiography) with Min-IP were performed over the tumor and its surrounding areas. SD-OCT showed an elevated tumor mass arising from the optic disc with increased reflectivity. PHOMS appeared ovoid in shape on B-scan OCT image. PHOMS appeared peripapillary hyperreflective bright areas on en-face Min-IP image corresponding to PHOMS on B-scan OCT image. The fluorescein angiography (FA) showed the staining of PHOMS. A diagnosis of optic disc melanocytoma with PHOMS was established prompting the patient to be advised for regular follow-up. Conclusion The optic disc melanocytoma with PHOMS is a rare benign ocular lesion that requires minimal active intervention, but demands a lifetime follow-up. The multimodal imaging and Min-IP images have clinical diagnostic value.","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139966149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0