Ibrahim Abdullahi Mohamed, Abdullahi Abdirahman Omar, Mulki Mukhtar Hassan, Mohamed Abdulahi Hassan, Zakaria Mohamed Adan, Zubeir Abdulkadir Mohamed
{"title":"Intracerebral Hemorrhage: A Fatal Complication of Severe Preeclampsia-A Rare Case Report in a Resource-Limited Setting.","authors":"Ibrahim Abdullahi Mohamed, Abdullahi Abdirahman Omar, Mulki Mukhtar Hassan, Mohamed Abdulahi Hassan, Zakaria Mohamed Adan, Zubeir Abdulkadir Mohamed","doi":"10.2147/IMCRJ.S516956","DOIUrl":"https://doi.org/10.2147/IMCRJ.S516956","url":null,"abstract":"<p><strong>Background: </strong>Intracerebral hemorrhage (ICH) is a rare but severe complication of preeclampsia, significantly contributing to maternal morbidity and mortality, particularly in resource-limited settings. The underlying mechanisms include endothelial dysfunction, cerebral autoregulation failure, and breakdown of the blood-brain barrier. This case report aims to highlight a unique presentation of severe preeclampsia complicated by ICH, emphasizing barriers encountered in resource-limited settings and discussing long-term implications and prognosis.</p><p><strong>Case presentation: </strong>A 35-year-old multiparous woman presented two days postpartum with altered mental status, aphasia, and right-sided hemiparesis. Her pregnancy was complicated by severe preeclampsia and intrauterine fetal death. Computed tomography (CT) revealed a left basal ganglia hemorrhage extending into the ventricles. She received conservative management including antihypertensive medications, magnesium sulfate for seizure prophylaxis, and anti-edema therapy. Despite limited diagnostic resources, laboratory evaluations ruled out coagulopathies and vascular anomalies. After 20 days of multidisciplinary care, significant neurological recovery was achieved. Follow-up after four weeks demonstrated complete functional recovery, with resolution confirmed by repeat CT.</p><p><strong>Conclusion: </strong>This case uniquely underscores the critical importance of timely multidisciplinary care and robust antenatal monitoring in mitigating severe complications such as ICH associated with preeclampsia. The patient's full recovery highlights the potential for successful conservative management even in resource-constrained environments. Future clinical practice and research should focus on improving antenatal care accessibility, patient education, and developing context-specific management guidelines to reduce maternal morbidity and mortality in similar settings.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"545-551"},"PeriodicalIF":0.7,"publicationDate":"2025-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12080481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anas Alrusan, Suhaib Bani Essa, Saif Aldin Naif Rawabdeh, Yazan Anaqreh, Modather Hatamleh, Mohammad Alradaideh, Mohammed Baker, Abdelwahab Aleshawi
{"title":"Successful Management of a Complicated Forearm Fracture in a Patient with Congenital Insensitivity to Pain: A Case Report.","authors":"Anas Alrusan, Suhaib Bani Essa, Saif Aldin Naif Rawabdeh, Yazan Anaqreh, Modather Hatamleh, Mohammad Alradaideh, Mohammed Baker, Abdelwahab Aleshawi","doi":"10.2147/IMCRJ.S514415","DOIUrl":"https://doi.org/10.2147/IMCRJ.S514415","url":null,"abstract":"<p><strong>Background: </strong>Congenital insensitivity to pain (CIPA) is an extremely rare syndrome that is caused by a mutation in the NTRK gene. CIPA is characterized by recurrent episodes of unexplained fever, infections, skeletal complications, anhidrosis, mental retardation, and ocular injuries due to the absence of reaction to painful stimuli. Several musculoskeletal complications have been reported and included fractures, avascular necrosis, joint dislocations, soft tissue, and bone infections. The severity of these complications presented complex diagnostic and therapeutic dilemmas. The collaboration of medical professionals from different specialties to provide appropriate medical care is needed.</p><p><strong>Case presentation: </strong>We present a case of a 1-year-old girl, diagnosed with CIPA, admitted to our center complaining of wound discharge and fever from a previously repaired left forearm fracture with nail insertion, which was found to be infected after a failed trial of nail removal. A multidisciplinary- management from anesthesia, orthopedics, ophthalmology, and pediatrics was conducted. The patient underwent successful nail removal, wound debridement, and radius bone reduction with the appropriate anesthetic protocol that did not include analgesic medications. The follow-up course was uneventful with proper alignment and virtually stable health status, with no apparent skeletal or ocular complications.</p><p><strong>Conclusion: </strong>This report shows a case of CIPA with complicated forearm fracture. Patients with CIPA should be afforded a multidisciplinary healthcare approach in order to improve their quality of life and decrease the rate of complications. Parents and patients should be educated promptly. Orthopedics complications imply significant morbidity and require prompt surgical intervention with intense follow-up.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"539-543"},"PeriodicalIF":0.7,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12078787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Pedigree Study of Hereditary Diabetes Insipidus Caused by X Chromosome AVPR2 Gene Mutation.","authors":"Lei Li, Yong Fan, Guoli Du, Jing Xu, Sheng Jiang","doi":"10.2147/IMCRJ.S514461","DOIUrl":"https://doi.org/10.2147/IMCRJ.S514461","url":null,"abstract":"<p><p>A case of hereditary nephrogenic diabetes insipidus (CNDI) in a Chinese Hui family is reported in this study. By comprehensively analysing the clinical symptoms, genetic test results and treatment outcomes of the family members, we confirmed that the c.818C>T(p.T273M) missense mutation in the AVPR2 gene was the underlying cause of the development of CNDI in this family. This study not only revealed the importance of genetic testing in the diagnosis and treatment of CNDI, but also unexpectedly revealed that desmopressin may have favorable therapeutic efficacy in the context of this specific mutation. In addition, this study provides information on genetic counseling, prenatal screening, and psychosocial implications of CNDI, which may inform the management of similar cases.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"529-538"},"PeriodicalIF":0.7,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12054539/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143971265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ectopic Pregnancy within a Cesarean Section Scar: An Unusual Case Report.","authors":"Emad M Al-Osail, Sager Almulhim","doi":"10.2147/IMCRJ.S515912","DOIUrl":"https://doi.org/10.2147/IMCRJ.S515912","url":null,"abstract":"<p><p>Ectopic pregnancy represents a significant challenge in obstetrics due to its potential for severe complications, including maternal morbidity and mortality. Caesarean scar ectopic pregnancy is one of the very rare sites of ectopic pregnancy. Any type of surgical scar on the uterine wall (hysterotomy) including caesarean section, myomectomy or history of abnormally adherent placenta or manual removal of placenta increases the risk of surgical scar ectopic pregnancy. Here, we have described a case of caesarean scar ectopic pregnancy in a 43 years female presenting to the emergency department after being referred from a primary centre with complaints of pelvic pain and vaginal bleeding. Ultrasound confirmed the diagnosis of caesarean section scar ectopic pregnancy. The patient was successfully managed with multi dose regime of methotrexate. Early diagnosis and prompt management of caesarean scar ectopic pregnancy is essential to avoid any life-threatening complications or loss of fertility.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"521-527"},"PeriodicalIF":0.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nadia Tiara Putri, Dhini Karina Octaviani, Dewi Zakiawati
{"title":"Anxiety and Sun Exposure as Triggers for Herpes Labialis: A Case Report and Review of Literature.","authors":"Nadia Tiara Putri, Dhini Karina Octaviani, Dewi Zakiawati","doi":"10.2147/IMCRJ.S507733","DOIUrl":"https://doi.org/10.2147/IMCRJ.S507733","url":null,"abstract":"<p><strong>Introduction: </strong>Herpes labialis (HL) is a prevalent viral infection caused by herpes simplex virus type 1 (HSV-1), affecting a significant portion of the global population. The reactivation of HSV-1 leading to HL can be triggered by various factors, including psychosocial factors (depression, stress, and anxiety), exposure to ultraviolet light, a febrile environment, and specific dietary inadequacy.</p><p><strong>Purpose: </strong>This case report explores the association between HL, psychological conditions, and sun exposure.</p><p><strong>Case report: </strong>A 20-year-old male patient came with a chief complaint of swollen lips with tiny pimples for two days, accompanied by malaise. The patient was working as a florist in a sun-exposed area and experiencing stress due to financial difficulties. Extraorally, multiple vesicles were found on the left side of the upper lip, surrounded by erythema, and painless. Laboratory examinations showed a reactive HSV-1 IgG. The depression, anxiety, and stress scale-21 (DASS-21) questionnaire showed an extremely severe level of anxiety.</p><p><strong>Case management: </strong>The patient was given systemic and topical acyclovir, multivitamins, hyaluronic acid mouthwash, and petroleum jelly. In addition, the patient was advised to reduce the frequency of sun exposure, apply sunscreen, and seek professional help to manage the anxiety. A review of eight case reports related to HL from 1994-2024 has been reported in this literature and emphasizes the connection of HL with psychological factors and sun exposure.</p><p><strong>Conclusion: </strong>This case underscores the potential link between anxiety, sun exposure, and the onset of HL. Understanding these associations is crucial for effective management and prevention strategies.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"509-519"},"PeriodicalIF":0.7,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12036686/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143987552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdishakur Mohamud Ahmed, Ahmed Omer Mead, Mohamed Abdullahi Awale, Omar Hassan Ahmed
{"title":"Solid Variant of Aneurysmal Bone Cyst (SVABC) of the Left Fibula Bone: A Rare Case Report.","authors":"Abdishakur Mohamud Ahmed, Ahmed Omer Mead, Mohamed Abdullahi Awale, Omar Hassan Ahmed","doi":"10.2147/IMCRJ.S511228","DOIUrl":"https://doi.org/10.2147/IMCRJ.S511228","url":null,"abstract":"<p><strong>Introduction: </strong>Solid variant of aneurysmal bone cyst (SVABC) is a rare subtype of aneurysmal bone cyst (ABC) that presents as a solid, densely sclerotic lesion that can be more difficult to distinguish from other bone tumors and can lead to a wrong diagnosis. The SVABC rarely occurs in the long bones of the lower extremities.</p><p><strong>Case presentation: </strong>In this report, we present a rare case of SVABC in a 25-year-old male patient, which was seen in the left fibula bone. The patient had a history of trauma for 7 years. A physical examination showed a non-tender swelling in his left fibula bone. A preoperative frontal radiograph showed a huge expansile lytic lesion with trabeculations in the proximal 2/3 of the left fibula. Magnetic Resonance Imaging (MRI) showed fibula with multiple cystic areas in the lesion, some containing fluid-fluid levels. Excision of the mass was performed. Histopathological examination of the surgical specimen of the left fibula mass confirmed that the lesion was SVABC and showed largely solid proliferation of mildly pleomorphic oval to spindle cells with giant cells. A postoperative frontal radiograph of the leg demonstrated proximal 2/3 of the left fibulectomy with no lesion recurrence.</p><p><strong>Conclusion: </strong>SVABC of the left fibula bone is a rare condition often misdiagnosed due to overlapping features with other aggressive bone lesions. Accurate diagnosis necessitates a multidisciplinary approach integrating clinical, imaging, and histopathology, with early surgical intervention being the gold standard for favorable outcomes. Surgeons must be cautious of postoperative complications like bleeding and neurological deficits, emphasizing the role of histopathology in preventing unnecessary surgeries. Future studies should focus on long-term follow-up and comparative treatment efficacy studies to enhance understanding and management of SVABC.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"499-507"},"PeriodicalIF":0.7,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12024465/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fareed Ahmad Nazari, Said Karim Zarif, Ghulam Yahia Baset, Soma Katawazai
{"title":"A Huge Mesenteric Chylous Cyst, Presenting as Abdominal Mass: A Rare Case Report.","authors":"Fareed Ahmad Nazari, Said Karim Zarif, Ghulam Yahia Baset, Soma Katawazai","doi":"10.2147/IMCRJ.S513146","DOIUrl":"https://doi.org/10.2147/IMCRJ.S513146","url":null,"abstract":"<p><p>Mesenteric cysts are rare abdominal lesions. A mesenteric chylous cyst is a very rare type of mesenteric cyst that may occur anywhere through the bowel, from the duodenum to the rectum. The etiology of mesenteric cysts is unknown and several theories have been suggested for forming these cysts. A mesenteric cyst is mostly found incidentally during investigations for another pathology. The treatment of choice for mesenteric chylous cysts in symptomatic patients is complete excision (enucleation) by either laparoscopic or open technique. The prognosis of a completely excised mesenteric cyst is generally good and its malignant transformation is reported to be around 3%. We present a case of mesenteric chylous cyst in a 60-year-old female presented with abdominal pain, constipation, nausea, and vomiting, who underwent laparotomy and complete cyst excision rate. The purpose of this case report is to consider mesenteric chylous cyst in the differential diagnosis of all abdominal masses.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"493-497"},"PeriodicalIF":0.7,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013624/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cheol-Jung Yang, Sin-Hye Park, Je Hun Lee, Taek-Sung Kim, Jeong-Won Seong
{"title":"Effective Treatment of Acute Wrist Pain in a Competitive Weightlifter Using Tendon Traction Point-Focused Dextrose Injections: A Case Report.","authors":"Cheol-Jung Yang, Sin-Hye Park, Je Hun Lee, Taek-Sung Kim, Jeong-Won Seong","doi":"10.2147/IMCRJ.S510696","DOIUrl":"https://doi.org/10.2147/IMCRJ.S510696","url":null,"abstract":"<p><p>Wrist pain is common among athletes, particularly weightlifters, who perform repetitive high-intensity movements like the snatch and clean and jerk. Conventional treatments, including NSAIDs, corticosteroids, and physical therapy, often provide only symptomatic relief. This case report highlights effective management of acute wrist pain in a competitive weightlifter using Tendon Traction Point (TTP)-focused dextrose injections. A 23-year-old weightlifter presented with wrist pain persisting for two weeks despite prior treatments. Tenosynovitis of the extensor digitorum communis (EDC) and extensor carpi radialis brevis (ECRB) tendons was confirmed by ultrasound. After four injections of 5% dextrose into identified TTPs, the patient's Visual Analog Scale (VAS) score improved from 7 to 1. The treatment relieved pain and enabled the athlete to return to competition. This report demonstrates that TTP-focused dextrose injections offer a rapid, effective, and non-invasive solution for athletes with tendon overuse pain, presenting a promising alternative to traditional therapies and supporting functional recovery.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"487-492"},"PeriodicalIF":0.7,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013641/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144012197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ex vivo Liver Autotransplantation for Alveolar Echinococcosis with Brain and Lung Metastases: A Case Report.","authors":"Anuar Abdikarimov, Yerzhan Shayakhmetov, Vitaliy Kalina, Saken Saberbekov, Nurbek Ilyassov, Erlan Nurgaliev, Yerlan Omarov","doi":"10.2147/IMCRJ.S507833","DOIUrl":"https://doi.org/10.2147/IMCRJ.S507833","url":null,"abstract":"<p><p>Ex vivo liver resection and autotransplantation (ELRA) in extensive abdominal alveolar echinococcosis (AE) is a relatively rare treatment. We present the first case, ever reported in Kazakhstan, of successfully performed ELRA of a patient with extensive abdominal AE with invasion into the inferior vena cava (IVC). A 64-year-old woman was diagnosed with AE of the brain, alveococcectomy from the left frontal lobe was performed. At the same time, liver AE metastased to the lungs and brain was diagnosed. The patient was admitted to our center for the following surgical treatments: (1) laparotomy, (2) extended left hemihepatectomy with resection of IVC ex vivo, (3) plastic surgery of IVC with a synthetic prosthesis, (4) orthotopic transplantation of the remnant right lobe of the liver. The postoperative period proceeded smoothly. The patient was mechanically ventilated for 1.5 days and prescribed strict bed rest with in-bed activity for up to 11 days. Empirical antibiotic therapy was initiated as follows: meropenem 1000 mg three times a day for 10 days, omeprazole 40 mg once a day for 14 days, anticoagulant therapy was not administered in the first post-operation day due to high risk of bleeding. Clexane was prescribed subcutaneously once a day: 0.2 mL for 2 days, then 0.4 mL for next 10 days. Daily transfusion of 100 mL of 10% Albumin was performed to prevent hypoalbuminemia. Drainage systems were removed on the 9th day. On the 12th day, the patient was transferred from the intensive care unit to a hospital room, and discharged with improvement on the 20th day. During a 6-month follow-up, no relapse was observed. Radical surgery for widespread AE, in this case - ELRA, is the preferred treatment, since it does not require immunosuppressive therapy and is quite feasible even with invasion of the portal vein bifurcation, IVC and hepatocaval confluence.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"473-478"},"PeriodicalIF":0.7,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11980938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143990142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Cristina Pedrosa Do Monte, Heloisa Ramos Lacerda
{"title":"Fetal and Neonatal Deaths Resulting from Chikungunya Virus Infection During Pregnancy: A Case Series.","authors":"Ana Cristina Pedrosa Do Monte, Heloisa Ramos Lacerda","doi":"10.2147/IMCRJ.S506873","DOIUrl":"https://doi.org/10.2147/IMCRJ.S506873","url":null,"abstract":"<p><strong>Purpose: </strong>We report maternal outcomes, fetal and neonatal deaths resulting from chikungunya virus (CHIKV) infection during pregnancy, addressing clinical manifestations, complications and laboratory changes.</p><p><strong>Patients and methods: </strong>This case series included four pregnant women infected with the chikungunya virus during gestation, three fetal deaths, and two neonatal deaths confirmed as resulting from maternal-fetal transmission, during an epidemic in 2015 and 2016, in the state of Pernambuco, Northeastern Brazil. Laboratory and clinical-epidemiological criteria were applied to confirm the infection.</p><p><strong>Results: </strong>All the pregnant women were symptomatic with an onset of symptoms from the first trimester of pregnancy until 4 days after birth, with the infection confirmed by laboratory and clinical-epidemiological criteria. Among the fetal deaths, changes in the brain were the most prominent (softening and autolysis). In the neonatal deaths, there were signs of acute suffering, and low Apgar, in addition to the manifestation of severe disease with skin hyperpigmentation, limb edema, and encephalitis.</p><p><strong>Conclusion: </strong>We demonstrate the rare, although possible, occurrence of fetal death due to maternal CHIKV infection at any stage of pregnancy, as well as the risk of vertical transmission during birth, resulting in neonatal mortality. We would suggest that during epidemics this diagnosis should be considered in fetal and neonatal deaths of mothers with symptoms suggestive of chikungunya.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"479-485"},"PeriodicalIF":0.7,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11980800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}