International Medical Case Reports Journal最新文献

{"title":"Platelet-Rich Plasma Therapy in Premature Ovarian Insufficiency: A Case Series of IVF Outcomes.","authors":"Rina Nulianti, Syahnural Lubis, Tita Husnitawati Madjid, Wiryawan Permadi, Putri Nadhira Adinda Adriansyah, Aisyah Shofiatun Nisa","doi":"10.2147/IMCRJ.S527318","DOIUrl":"10.2147/IMCRJ.S527318","url":null,"abstract":"<p><strong>Introduction: </strong>Premature ovarian insufficiency (POI) leads to the early loss of ovarian function before age 40, resulting in infertility and hormonal imbalance. Despite the use of assisted reproductive technologies (ART), success rates remain low in this population. Platelet-rich plasma (PRP) therapy is emerging as a potential adjunct to enhance ovarian reserve.</p><p><strong>Case illustrationcase 1: </strong>A 25-year-old nulliparous woman with a history of ectopic pregnancy and an anti-Müllerian hormone (AMH) level below 1 ng/mL received two PRP injections scheduled between days 7 to 12 of her cycle. After the first injection, her AMH level remained <0.5 ng/mL. Following the second PRP injection, her AMH level increased to >0.5 ng/mL. A frozen embryo transfer resulted in a successful term pregnancy and healthy newborn.</p><p><strong>Case 2: </strong>A 36-year-old nulliparous woman, married for seven years, also presented POI and AMH levels <1 ng/mL followed the same PRP and IVF protocol. After two PRP sessions, her AMH levels improved similarly to Case 1. Despite an initial pregnancy, the patient experienced pregnancy loss.</p><p><strong>Conclusion: </strong>These findings suggest that PRP may improve ovarian response in women with POI undergoing IVF. Further studies are warranted.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"859-867"},"PeriodicalIF":0.7,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12255267/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multidisciplinary Management of Paraneoplastic Pemphigus Associated with B-Cell Lymphoma: A Case Report.","authors":"Loulwah Alothman, Azizah Bin Mubayrik, Nuha Alfurayh, Sara Aldosary, Hend M Alotaibi, Abdulmajeed Alajlan","doi":"10.2147/IMCRJ.S515068","DOIUrl":"10.2147/IMCRJ.S515068","url":null,"abstract":"<p><strong>Background: </strong>Paraneoplastic pemphigus is a rare life-threatening blistering autoimmune mucocutaneous disease associated with various neoplasms. In contrast to the skin, mucosal lesions are refractory and requires considerable healing time, heals far more slowly. A multidisciplinary approach may provide a comprehensive management and a better prognosis.</p><p><strong>Case summary: </strong>A sixty-one-year-old male patient presented to the ER department in June 2020 complaining of severe inflammation of the left eye along with scaly erythematous skin eruptions affecting the hands, trunk, and feet. Subungual hematoma was also observed. Clinical examination revealed extensive oral ulceration involving the dorsum and ventral surface of the tongue, buccal mucosa, labial mucosa, and hematic crusts were noticed on the lips. The patient was admitted for panophthalmitis secondary to a perforated corneal ulcer. Dermatological investigations were requested in addition to extensive baseline studies to rule out malignancies. The patient had a retroperitoneal lesion and underwent CT guided biopsy. Result was suggestive of low-grade B cell non-Hodgkin's lymphoma. He was treated by the haematology-oncology, dermatology and oral medicine teams.</p><p><strong>Conclusion: </strong>Paraneoplastic pemphigus (PP) is a fatal autoimmune blistering disease associated with underlying malignancy. A multidisciplinary approach to achieve early diagnosis and better management is essential to improve the quality of life of such patients despite their poor prognosis.</p><p><strong>Clinical significance: </strong>Paraneoplastic pemphigus is a rare disease associated with mucocutaneous ulcerations and various malignancies, including lymphoproliferative neoplasms. As demonstrated in the current case, multidisciplinary assessment and management have proven to be effective in managing the patient. Physicians and dentists should make their best effort to work collaboratively to manage patients and minimize patient distress and improve life quality and prognosis.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"851-857"},"PeriodicalIF":0.7,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12255323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progressive Deterioration of the Right Ventricular Function in a Patient with Non-Obstructive HCM Complicated by Atrial Fibrillation: A Case Presentation.","authors":"Jiamin Xu, Changshou Tan, Jianzhou Chen, Jiaxin Hu","doi":"10.2147/IMCRJ.S529591","DOIUrl":"10.2147/IMCRJ.S529591","url":null,"abstract":"<p><strong>Background: </strong>Hypertrophic cardiomyopathy (HCM) is a prevalent monogenic hereditary cardiovascular disorder caused by a mutation in one of the several sarcomere genes encoding components of the cardiac contractile system, distinguished by varied phenotypic presentation and fluctuating clinical advancement. HCM typically affects the left ventricle, resulting in impaired left ventricular function, instances of impaired right ventricular function are uncommon. This case study presents a rare occurrence of HCM accompanied by deteriorating right ventricular function, providing valuable insights for clinicians.</p><p><strong>Case presentation: </strong>Herein, we present a case study of an individual diagnosed with HCM utilizing next-generation sequencing (NGS). Over the disease course, the patient with hypertrophic cardiomyopathy also presented with sustained atrial fibrillation, characterized by progressive right ventricular dysfunction, resulting in the development of peripheral edema and ascites.</p><p><strong>Conclusion: </strong>We report the case of a patient with non-obstructive HCM exhibiting progressive decline in right heart function, confirmed to have the c.470C>T (p.Ala157Val) mutation in exon 7 of the TNNI3 gene.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"837-843"},"PeriodicalIF":0.7,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12254914/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges in Diagnosis and Management of Acute Limb Ischemia 30 Days Postpartum in Lithotomy Position: A Case Report from Somalia Leading to Bilateral Lower Limb Amputation.","authors":"Ubah Mumin Ali Osman, Halwo Bashir Adan, Hanan Hassan Hirei, Yahye Sheikh Abdulle Hassan","doi":"10.2147/IMCRJ.S478373","DOIUrl":"10.2147/IMCRJ.S478373","url":null,"abstract":"<p><p>Acute limb ischemia in postpartum women is a rare and severe vascular emergency that can lead to significant complications if not promptly diagnosed and managed. A 31-year-old woman, 30 days postpartum following uncomplicated vaginal delivery in the lithotomy position, presented with bilateral lower limb paralysis and paresthesia There was no history of trauma, falls, or use of assistive instruments during delivery. The patient weighed 65 kg and was 162 cm tall, while the infant had a birth weight of 2.8 kg. Initial suspicion of a neurological condition was later ruled out through imaging, including thoracolumbar MRI and CT angiography, which revealed bilateral arterial occlusions. Despite timely thromboembolectomy, the patient underwent bilateral below-knee amputation due to progressive ischemia. This case highlights the diagnostic challenges of acute limb ischemia in postpartum patients, stressing the crucial role of early imaging and prompt multidisciplinary intervention in preventing severe outcomes. Increased clinical vigilance and timely investigations are vital for improving prognosis and reducing the risk of limb loss.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"845-850"},"PeriodicalIF":0.7,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12248728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surviving Unrepaired Tetralogy of Fallot to 43 Years in a Low-Resource Setting: The Oldest Reported Case from Somalia.","authors":"Abdirahman A Warfaa, Abdirahman Ibrahim Said, Mohamoud Abdulahi, Mohamed Said Hassan","doi":"10.2147/IMCRJ.S529873","DOIUrl":"10.2147/IMCRJ.S529873","url":null,"abstract":"<p><strong>Introduction: </strong>Tetralogy of Fallot (ToF) is a congenital heart defect characterized by a combination of four anomalies: right ventricular hypertrophy, ventricular septal defect (VSD), right ventricular outflow tract (RVOT) obstruction, and an overriding aorta. While surgical interventions have significantly improved the prognosis of ToF, cases of undiagnosed or untreated ToF in adulthood remain, particularly in low-resource settings. This report highlights the case of an adult patient with uncorrected ToF, underscoring the challenges individuals face in such environments.</p><p><strong>Case report: </strong>A 43-year-old male from Somalia presented with recurrent syncope, exertional dyspnea, and a history of congenital heart disease diagnosed in childhood. Due to financial constraints and limited healthcare access, he was unable to undergo surgery. On clinical examination, the patient exhibited cyanosis, grade 3 clubbing, and a pansystolic murmur. Investigations showed secondary polycythemia, right ventricular hypertrophy on ECG, and a large VSD with an overriding aorta. Echocardiography confirmed these findings, revealing the anatomical abnormalities typical of ToF.</p><p><strong>Discussion: </strong>Untreated ToF often leads to significant morbidity, including worsening cyanosis, syncope, and heart failure. In this case, delayed surgical intervention and lack of resources contributed to the progression of symptoms. The patient's case emphasizes the importance of early diagnosis and surgical repair, particularly in resource-limited settings where access to advanced care is limited.</p><p><strong>Conclusion: </strong>This case highlights the critical need for early intervention and improved healthcare access for individuals with congenital heart defects in low-income settings. Timely diagnosis, surgical repair, and ongoing care can substantially improve outcomes for patients with ToF.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"827-835"},"PeriodicalIF":0.7,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infection Leading to Breast Abscess Formation in Pregnancy: A Case Report.","authors":"Jiangting Yu, Jiaying Chen, Tianjian Huang, Xidong Gu","doi":"10.2147/IMCRJ.S512859","DOIUrl":"10.2147/IMCRJ.S512859","url":null,"abstract":"<p><strong>Introduction: </strong>Breast abscess, the most severe complication of mastitis, occurs when an infection spreads through the nipple into the breast tissue, contaminating the milk ducts and forming a purulent cavity. Nonetheless, this condition is less common in pregnant women. <i>Staphylococcus aureus</i> is the predominant causative agent in lactating women; however, <i>Prevotella bivia</i>-associated breast abscesses during pregnancy remain clinically rare, with limited documented cases.</p><p><strong>Case presentation: </strong>A 26-year-old Chinese woman with G1P0 singleton at 33 weeks of pregnancy presented with right breast pain and lumps without obvious triggers, accompanied by enlarged right axillary lymph nodes and a large amount of pus with a peculiar odor in the right breast. After breast ultrasonography, cytological puncture smear, pus culture, and metagenomic next-generation sequencing, the patient was confirmed to have gestational mastitis with <i>P. bivia</i> infection. Given that the patient had a high-risk pregnancy, the use of antibiotics sensitive to <i>Prevotella</i>, such as metronidazole, might affect the intrauterine fetus, and infection with this bacterium could increase the risk of placental abruption and intrauterine fetal distress. Based on the obstetrician's and pediatrician's recommendations, the patient opted for a cesarean section at 37 weeks to facilitate the delivery of a healthy neonate weighing 3110 g (Apgar scores of 10 at 1 min and 5 min) in the left anterior sacral position and was advised to opt for lactation-suppressing medication and postpartum antibiotics.</p><p><strong>Conclusion: </strong>This case highlights the importance of close monitoring of pus characteristics (eg, color, odor, and volume) in pregnancy-associated breast abscesses to expedite the diagnosis of infectious mastitis and pathogen identification. Treatment with small incision drainage and targeted antibiotics during pregnancy significantly improved the outcomes. Postpartum breast milk return and combined antibiotic therapy further contributed to the resolution of inflammation.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"791-809"},"PeriodicalIF":0.7,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pomeroy Sterilization in a Teen with Recurrent Pregnancy and Multiple Cesarean Deliveries: A Case Report.","authors":"Windi Nurdiawan, Aisyah Shofiatun Nisa, Hadi Susiarno, Dini Hidayat, Dini Pusianawati, Zulvayanti, Ayu Angelina Ronosulistyo, Putri Nadhira Adinda Adriansyah","doi":"10.2147/IMCRJ.S527311","DOIUrl":"10.2147/IMCRJ.S527311","url":null,"abstract":"<p><strong>Introduction: </strong>Recurrent teenage pregnancy refers to an adolescent experiencing more than one pregnancy before reaching full adulthood. Pomeroy sterilization in teenagers with a history of two cesarean sections presents a complex issue requiring careful consideration of medical, ethical, and social factors. This case highlights the appropriate management of adolescents in such situations.</p><p><strong>Case illustration: </strong>An 18-year-old woman, G3P2A0, at full-term pregnancy, presented for elective cesarean section. The patient had no complaints and exhibited no signs of labor at the time of admission. Laboratory findings revealed anemia, with a hemoglobin level of 7.2 g/dL. She received two units of packed red cell (PRC) transfusions preoperatively. A cesarean section was performed, delivering a healthy baby boy weighing 2720 grams and measuring 47 cm. After a thorough discussion and informed consent regarding contraceptive options, the patient and her husband opted for Pomeroy sterilization, as they felt their family was complete.</p><p><strong>Conclusion: </strong>Managing teenage pregnancy requires a holistic and cautious approach, especially in cases involving previous cesarean sections. Comprehensive care, including monitoring for complications such as anemia and fetal growth restriction, is essential for ensuring maternal and neonatal health. Furthermore, informed decision-making regarding contraception is vital to prevent recurrent pregnancies and support the psychosocial well-being of adolescent mothers. This approach helps achieve better outcomes for both mother and child.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"817-826"},"PeriodicalIF":0.7,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12236957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144591224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrograde Surgical Placement of a Thoracic Epidural Catheter in a Patient Undergoing Combined Thoracic and Spinal Surgery.","authors":"Vanessa B Davis, Mark Li, Flora Mian Li, Ryu Komatsu, Jiang Wu","doi":"10.2147/IMCRJ.S532166","DOIUrl":"10.2147/IMCRJ.S532166","url":null,"abstract":"<p><p>Epidural anesthetic techniques for postoperative analgesia are rarely considered in spinal surgery, and high thoracic epidural analgesia (TEA) is considered medically risky. We present a successful case of surgical retrograde placement of a thoracic (T6-T7) epidural catheter under direct surgical visualization via T2 laminectomy in a patient who underwent combined thoracotomy and spinal surgery. TEA was confirmed by epidurogram, provided adequate postoperative pain relief, and the patient was discharged home three days post-surgery.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"785-790"},"PeriodicalIF":0.7,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12233021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Late Presentation of Isolated Persistent Left Superior Vena Cava with Absent Right Superior Vena Cava Manifesting as Heart Failure: A Case Report.","authors":"Said Abdirahman Ahmed, Osman Farah Dahir, Ahmed Elmi Abdi, Ahmed Shafie Adan, Ishak Ahmed Abdi, Mohamud Mire Waberi, Mohamed Abdullahi Mohamud, Abdullahi Mohamed Hassan Fujeyra, Abdijalil Abdullahi Ali, Mohammed A M Ahmed, Bakar Ali Adan Ali, Mohamed Sheikh Hassan, Feyza Aksu, Mahad Sadik Mukhtar, Ismail Gedi Ibrahim, Mohamed Omar Hassan","doi":"10.2147/IMCRJ.S525707","DOIUrl":"10.2147/IMCRJ.S525707","url":null,"abstract":"<p><strong>Background: </strong>Persistent left superior vena cava (PLSVC) with absent right superior vena cava (RSVC) is a rare congenital venous anomaly, typically asymptomatic and discovered incidentally. In rare cases, it may contribute to hemodynamic disturbances and arrhythmias, potentially leading to heart failure, especially when associated with other cardiac anomalies or conduction abnormalities.</p><p><strong>Case presentation: </strong>We report the case of a 45-year-old male who presented with progressive symptoms of heart failure, including dyspnea, fatigue, and reduced exercise tolerance. Initial workup revealed an unexplained dilated coronary sinus and reduced left ventricular function with dilated heart chambers. Further imaging with contrast-enhanced echocardiography and CT angiography confirmed the presence of a PLSVC draining into the coronary sinus with absence of right superior vena cava. No other congenital heart defects were identified like coronary sinus atrial septal defect (ASD). The delayed diagnosis of PLSVC likely contributed to chronic atrial stretch, arrhythmia development- atrial fibrillation in this case, and eventual heart failure symptoms.</p><p><strong>Conclusion: </strong>This case highlights the importance of considering vascular anomalies like PLSVC in the differential diagnosis of unexplained heart failure or dilated coronary sinus. Early detection through appropriate imaging can guide management and potentially prevent progression of symptoms.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"811-816"},"PeriodicalIF":0.7,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12232947/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Valsalva Retinopathy in Pregnancy: A Case Report and Review of the Literature.","authors":"Brenda Zhou, Faiza Sarwar, Noy Ashkenazy","doi":"10.2147/IMCRJ.S524362","DOIUrl":"10.2147/IMCRJ.S524362","url":null,"abstract":"<p><p>The current case report and literature review evaluate the management and optimal mode of delivery for Valsalva retinopathy in pregnancy. A 30-year-old primigravid female was discussed presenting with Valsalva retinopathy in the left eye at 35 weeks of gestation after dry heaving with a visual acuity of 20/200. Four weeks after cesarean-section, she had worse central vision and improving residual hemorrhage. A literature review of 25 Valsalva retinopathy cases showed all patients treated with laser posterior hyaloidotomy or pars plana vitrectomy achieved complete resolution (median of 1.5 weeks, p = 0.08), compared to 67% of untreated eyes (median of 5 months, p = 0.08). Average final visual acuity was 20/30 for the treated and untreated cohorts. Intervention may result in faster recovery time but with similar final visual acuity. Four (15%) cases of Valsalva retinopathy were incited by vaginal delivery. However, neither vaginal delivery nor cesarean section resulted in recurrence/worsening of premacular hemorrhage. These findings may help guide treatment of challenging Valsalva retinopathy cases in pregnancy.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"777-784"},"PeriodicalIF":0.7,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12227002/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144575462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}