International Medical Case Reports Journal最新文献_第10页

A Case of a Young Military Officer with Bilateral Simultaneous Femoral Neck Stress Fracture 一名年轻军官双侧股骨颈同时应力性骨折的病例

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International Medical Case Reports Journal Pub Date : 2024-02-01 DOI: 10.2147/imcrj.s411460

Z. Khired

引用次数: 0

Severe Xerostomia Induced by Multiple Systemic Diseases in a Patient with Psoriasis Vulgaris: A Case Report and Literature Review. 一名大面积银屑病患者因多种系统疾病引发的严重口腔干燥症：病例报告和文献综述。

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International Medical Case Reports Journal Pub Date : 2024-01-31 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S453097

Yessy Novianti, Wahyu Hidayat, Desi Elvhira Rosa

{"title":"Severe Xerostomia Induced by Multiple Systemic Diseases in a Patient with Psoriasis Vulgaris: A Case Report and Literature Review.","authors":"Yessy Novianti, Wahyu Hidayat, Desi Elvhira Rosa","doi":"10.2147/IMCRJ.S453097","DOIUrl":"10.2147/IMCRJ.S453097","url":null,"abstract":"Introduction: Psoriasis is a complex autoimmune disease associated with chronic systemic keratinization and inflammation, which can affect the skin, joints, and oral cavity. Xerostomia is a subjective feeling of oral dryness that impairs patient comfort and lowers the quality of life. The aim of this case report is to describe the clinical mechanism of xerostomia in a psoriasis patient with multiple systemic diseases.Case report: A 51-year-old inpatient man with psoriasis vulgaris was referred to the Oral Medicine Department with complaints of difficulty swallowing due to a sore throat and dry tongue since last week. The patient had psoriasis vulgaris 15 years ago, chronic adrenal insufficiency, psoriatic arthritis, acute circulatory collapse, anemia of inflammation, acute kidney injury, dehydration, gastritis, urinary tract infections, and malnutrition. A complete anamnesis and oral examination were done. The patient was diagnosed with severe xerostomia, a fissured tongue, exfoliative cheilitis, angular cheilitis, and gingivitis by the Oral Medicine Department.Case management: The patient was treated with petroleum jelly, chlorine dioxide mouthwash, miconazole cream, and benzydamine HCl lozenges.Conclusion: Based on case reports and reviews, multiple systemic diseases may not only increase the risk of xerostomia but also aggravate its severity.","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10838493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139681046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

c.1103T>C (p.Ile368Th) de novo Variant in Synaptotagmin 1 (SYT1) Gene is Pathogenic, Leading to an Ultra-Rare Neurodevelopmental Disorder: The Baker-Gordon Syndrome. c.1103T>C（p.Ile368Th）突触位点蛋白 1（SYT1）基因新变异具有致病性，导致一种超罕见的神经发育障碍：贝克-戈登综合征。

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International Medical Case Reports Journal Pub Date : 2024-01-24 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S448555

Milena Barbosa Porto, Geovanna da Mata E Castro, Samara Socorro Silva Pereira, Elza Maria Gonçalves Santos Uchoa, Raffael Zatarin, Lysa Bernardes Minasi, Aparecido D da Cruz

{"title":"c.1103T>C (p.Ile368Th) de novo Variant in Synaptotagmin 1 (SYT1) Gene is Pathogenic, Leading to an Ultra-Rare Neurodevelopmental Disorder: The Baker-Gordon Syndrome.","authors":"Milena Barbosa Porto, Geovanna da Mata E Castro, Samara Socorro Silva Pereira, Elza Maria Gonçalves Santos Uchoa, Raffael Zatarin, Lysa Bernardes Minasi, Aparecido D da Cruz","doi":"10.2147/IMCRJ.S448555","DOIUrl":"10.2147/IMCRJ.S448555","url":null,"abstract":"Baker-Gordon Syndrome (BAGOS) is a genetically determined 4 (NDD), represented by a phenotypic spectrum of moderate to severe intellectual disability, resulting from mutations in the synaptotagmin 1 (SYT1) gene. Its prevalence is estimated at 1:1,000,000 and the known gene variants have indicated complete penetrance with variable expressivity. SYT1 is a membrane trafficking protein in presynaptic vesicles, which exerts a complex influence on synaptic transmission, with fundamental roles in the release of neurotransmitters and facilitators of endocytosis, impacting both neurotransmission and neuron plasticity. The current case report describes the first Brazilian male patient diagnosed at 17-year-old, and the 39th reported case globally using whole-exome sequencing. A de novo heterozygous missense mutation at chr12q:79448958 (NM_005639.2; c.1103T>C; p.Ile368Thr) in the SYT1 was found and classified as a pathogenic variant. The proband's clinical phenotype was compatible with BAGOS, involving behavioral changes such as irritability and severe intellectual disability. Knowledge about the mechanism of action and the extent of the genotypic and phenotypic presentations of the mutations in the SYT1 is still unfolding. Thus, we aimed to describe additional genotype-phenotype correlation for BAGOS, contributing to the expansion of the existing knowledge of such a heterogeneous ultra-rare syndrome, and, therefore, improve its diagnostic yield, case management, and therapeutic journey for future patients.","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10822096/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139570243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Labisia pumila as a Culprit of Primary Uterine Rupture Alongside Abruptio Placentae: A Case Report. 阴唇是原发性子宫破裂并发胎盘早破的罪魁祸首：病例报告。

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International Medical Case Reports Journal Pub Date : 2024-01-22 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S442687

Luthfi Rahman, Kania Praharsini, Aditiyo Januajie, Ruswana Anwar

{"title":"Labisia pumila as a Culprit of Primary Uterine Rupture Alongside Abruptio Placentae: A Case Report.","authors":"Luthfi Rahman, Kania Praharsini, Aditiyo Januajie, Ruswana Anwar","doi":"10.2147/IMCRJ.S442687","DOIUrl":"10.2147/IMCRJ.S442687","url":null,"abstract":"Purpose: Uterine rupture is a rare obstetrical and surgical emergency but is often associated with a catastrophic obstetric complication. Traditionally, unscarred uteri without risk factors are considered immune to rupture and information about its risk factors is only few due to its rarity. Complementary and alternative medicine is commonly used in pregnant woman in southeast Asian countries such as Indonesia, however information regarding its toxicity due to irrational use is few. This case report presents a G2P1A0 35-year-old woman with acute abdomen with spontaneous unscarred uterine rupture >15 cm after continuously consuming herbal water made of Kacip Fatimah leaves in boiling water.Case description: A 35-year-old pregnant woman was referred to hospital due to abdominal discomfort 3 hours before admission due to suspicion of intrauterine fetal death. She drank the extracted herbal water to help her when the labor comes, which was made from boiled water with rumput Fatimah from her neighbor's house. Then, she was diagnosed with G2P1A0 parturient aterm latent phase; acute abdomen due to suspicion of placentae abruption dd/ ruptur uteri; and Intrauterine Fetal Death. Exploratory laparotomy was decided due to acute abdominal pain, and during the procedure the operator decided to do subtotal hysterectomy on the patient. The operator found her uterine was already ruptured, approximately 15-18 cm and the placentae was located outside of the uterus.Conclusion: This case suggest that rational usage of herbal medicine must be implemented to avoid unwanted complication.","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10812690/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139570175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case Series: Sacubitril/Valsartan Role for Chemotherapy-Induced Cardiotoxicity: An in-Depth Investigation in Saudi Arabia. 病例系列：沙奎利/缬沙坦在化疗引起的心脏毒性中的作用：沙特阿拉伯的一项深入调查。

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International Medical Case Reports Journal Pub Date : 2024-01-18 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S448913

Abdullah Alshammari, Basmah Ahmed Qasem, Nouf Ahmed Almatrafi, Lujain Mofareh Alharbi, Abeer Abdulhadi Alhuthali, Attiah Abdulrahman Khobrani, Mohammed Alnuhait

{"title":"Case Series: Sacubitril/Valsartan Role for Chemotherapy-Induced Cardiotoxicity: An in-Depth Investigation in Saudi Arabia.","authors":"Abdullah Alshammari, Basmah Ahmed Qasem, Nouf Ahmed Almatrafi, Lujain Mofareh Alharbi, Abeer Abdulhadi Alhuthali, Attiah Abdulrahman Khobrani, Mohammed Alnuhait","doi":"10.2147/IMCRJ.S448913","DOIUrl":"10.2147/IMCRJ.S448913","url":null,"abstract":"Background: Chemotherapy-induced cardiotoxicity is a significant problem, ranking as the second most frequent cause of mortality in cancer patients. This adverse outcome encompasses many cardiovascular problems, such as heart failure. Sacubitril/valsartan has shown potential in the management of heart failure, however, its effectiveness in treating chemotherapy-induced heart failure has not been extensively explored. We performed a case series to investigate the safety and effectiveness of sacubitril/valsartan in treating chemotherapy-induced cardiomyopathy in Saudi Arabia.Methods: The case series was conducted at a single medical center in Makkah, Saudi Arabia. The data gathered included patient demographics, clinical features, laboratory results, echocardiographic findings, and medication information. The data underwent analysis using descriptive statistics.Results: Out of the total of eight patients who were part of the investigation, a notable majority of six individuals exhibited substantial enhancements in their ejection fraction (EF) after receiving sacubitril/valsartan medication.Conclusion: Our case series provides significant insights by revealing improvements in ejection fraction (EF) in six out of eight patients who had chemotherapy-induced cardiomyopathy after receiving sacubitril/valsartan treatment.","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10804285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139542264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intramuscular Hemangioma of the Triceps Brachii Muscle: A Case Report. 肱三头肌肌内血管瘤：病例报告。

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International Medical Case Reports Journal Pub Date : 2024-01-17 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S441846

Cailiang Gao, Hu Wang, Huiting Liu

{"title":"Intramuscular Hemangioma of the Triceps Brachii Muscle: A Case Report.","authors":"Cailiang Gao, Hu Wang, Huiting Liu","doi":"10.2147/IMCRJ.S441846","DOIUrl":"10.2147/IMCRJ.S441846","url":null,"abstract":"Introduction: Intramuscular hemangioma (IMH) is a rare type of benign tumor that represents less than 1% of all hemangiomas. Chronic pain and a palpable mass are the most common symptoms. Due to the atypical clinical characteristics of the disease, accurate diagnosis is difficult. Misdiagnosis of IMH as malignancy can occur due to similarities in imaging features between IMH and malignancy. To diagnose IMH accurately, multiple imaging modalities, including X-ray, MRI, CT, and 18F-FDG PET/CT, can be used. However, the final diagnosis of IMH is confirmed through histopathological examination.Case: This case reports a 16-year-old girl diagnosed with IMH in the triceps brachii muscle. Seek medical attention due to pain and discomfort in the left shoulder. Initial imaging with contrast-enhanced MRI and CT suggested synovial sarcomata. The moderate uptake of FDG on positron emission tomography/computed tomography (PET/CT) also raised suspicions of malignancy. The pathological findings revealed an intramuscular hemangioma with thrombosis and thrombus organization.Conclusion: The accurate diagnosis of IMH can be challenging due to the absence of distinct clinical symptoms and imaging findings. When evaluating periarticular intramuscular lesions, IMH should be considered if the MRI shows mixed signals with heterogeneous enhancement. Despite the moderate uptake of FDG seen in some IMH cases, it should not automatically rule out the possibility of IMH. Hence, a combination of imaging modalities and histopathological examination is crucial in ensuring a correct diagnosis of IMH.","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10800111/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139512502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary Cardiac Sarcoma, Diagnostic and Therapeutic Challenges in Resource Limited Setting: Case Report 原发性心脏肉瘤，资源有限环境下的诊断和治疗难题：病例报告

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International Medical Case Reports Journal Pub Date : 2024-01-01 DOI: 10.2147/imcrj.s436528

M. Mulisa, Shalom Bekele, Sisay Woldemichael, Sitota Gaito, F. Abrar, Betelhem Hailu

引用次数: 0

Massive Airway Bleeding Caused by Pulmonary Strongyloidiasis in a Patient with a Transplanted Kidney 一名肾移植患者因肺结核引起的气道大出血

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International Medical Case Reports Journal Pub Date : 2024-01-01 DOI: 10.2147/imcrj.s442535

Longyin Zhu, Huhai Zhang, Jia Fang, Shuang Xiao, Fu Xiong, Caixia Deng, Qin Yang, Chunxiao Fu, Qianguang Pan, Hongwen Zhao

引用次数: 0

Missed Diagnosis of Perforation and Intraperitoneal Migration of an Intrauterine Device and Its Management in a Resource-Limited Setting: A Case Report 在资源有限的环境中，宫内节育器穿孔和腹膜内移位的漏诊及其处理：病例报告

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International Medical Case Reports Journal Pub Date : 2024-01-01 DOI: 10.2147/imcrj.s441386

A. Gebremichael, H. Teka, K. Abadi, Melkamu Siferih, Menberu Moges, Muhudin Arusi, Abel Shiferaw

引用次数: 0

A Case of Dermatomyositis with Coexistence of Positive Anti-MDA5 Antibodies and Anti-SSA/RO52 Antibodies, Combined with Necrotic Skin Ulcers 一例皮肌炎患者同时出现抗 MDA5 抗体和抗 SSA/RO52 抗体阳性，并伴有坏死性皮肤溃疡

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International Medical Case Reports Journal Pub Date : 2024-01-01 DOI: 10.2147/imcrj.s441691

Tian Sun, Zhong Hao Hu, Jin Shi He, Yu Chi Chen, Yong Xiang Gao

引用次数: 0