International Medical Case Reports Journal最新文献

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Heatstroke Comorbid with SARS-CoV-2 Infection: A Case Report and Literature Review. 中暑并发 SARS-CoV-2 感染:病例报告与文献综述
IF 0.9
International Medical Case Reports Journal Pub Date : 2024-05-30 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S461078
Xiao-Xiao Ni, Zhe-Ying Liu, Yan-Yan Zeng, Zhi-Feng Liu
{"title":"Heatstroke Comorbid with SARS-CoV-2 Infection: A Case Report and Literature Review.","authors":"Xiao-Xiao Ni, Zhe-Ying Liu, Yan-Yan Zeng, Zhi-Feng Liu","doi":"10.2147/IMCRJ.S461078","DOIUrl":"10.2147/IMCRJ.S461078","url":null,"abstract":"<p><strong>Background: </strong>Hyperthermia and multiple organ dysfunction syndrome (MODS) are the main characteristics of heatstroke and COVID-19. Differentiating between these illnesses is crucial during a summer COVID-19 pandemic, but cases of heatstroke comorbid with COVID-19 are rarely reported.</p><p><strong>Case description: </strong>We report the first case of heatstroke comorbid with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in a 52-year-old male. After receiving intravenous antibiotics, organ protection measures, and treatment for coagulation disorders, his fever and coma resolved. However, he developed dyspnea and cerebral hemorrhage after several days. This patient experienced a multi-pathogen pulmonary infection and an intractable coagulopathy that ultimately resulted in MODS and death.</p><p><strong>Conclusion: </strong>The combination of heatstroke and SARS-CoV-2 infection exacerbated inflammation, immune abnormalities, and coagulation disorders. The interaction between inflammation and coagulation disturbances contributed to the underlying mechanism in this case, highlighting the importance of early anti-infection, treatment for coagulopathy, immune regulation, and organ protection as crucial interventions.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11146621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141237663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vaping as a Risk Factor for Oral Erythema Multiforme: A Case Report and Literature Review. 吸烟是口腔多形红斑的风险因素:病例报告和文献综述。
IF 0.9
International Medical Case Reports Journal Pub Date : 2024-05-28 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S455640
Agustin Ninintowe T Santo, Wahyu Hidayat, Tenny Setiani Dewi
{"title":"Vaping as a Risk Factor for Oral Erythema Multiforme: A Case Report and Literature Review.","authors":"Agustin Ninintowe T Santo, Wahyu Hidayat, Tenny Setiani Dewi","doi":"10.2147/IMCRJ.S455640","DOIUrl":"10.2147/IMCRJ.S455640","url":null,"abstract":"<p><strong>Introduction: </strong>Erythema multiforme is a hypersensitivity reaction caused by various factors, such as viruses, chemicals, and drugs. Electronic cigarettes (e-cigarettes) or vape is a battery-powered nicotine delivery device that substitutes for traditional cigarettes. The chemical components of vaping, including propylene glycol and nicotine, can cause hypersensitivity reactions.</p><p><strong>Objective: </strong>To report a case of oral erythema multiforme in an e-cigarettes user, treatment, and review the literature regarding the impact of these devices on oral health.</p><p><strong>Clinical case: </strong>A 22-year-old woman came to the Oral Medicine Department with complaints of stomatitis causing pain, eating, and drinking difficulty, which started with fever and pimple-like on the lips. She was an active vape user for one year. Extraoral examination revealed no lesions on other body parts. The serosanguinolent crusts on the lips, an erosive area on the labial commissures and tended to bleed. Intraoral examination revealed white ulcers with yellowish edges and irregular, varying sizes in several parts of the oral mucosa. The anti-HSV-1 IgG laboratory results showed non-reactive, leading to a diagnosis of oral erythema multiforme. Management of oral conditions using 0.9% NaCl compress, dexamethasone mouthwash, and hyaluronic acid, applying 2% miconazole cream on labial commissures and vaseline album cream on the dry lips, and stopping vaping. Oral condition improved in a week of therapy.</p><p><strong>Conclusion: </strong>Erythema multiforme restricted to the mouth is rare, especially associated with electronic cigarettes. Early identification of oral ulcerative disorders is crucial for accurate diagnosis and treatment, where clinicians should consider oral erythema multiforme as a possible diagnosis.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11144004/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141199520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Minimally Invasive Direct Internal Cyclopexy in the Management of Goniotomy-Related Cyclodialysis Cleft with Hypotony Maculopathy. 微创直接内环切术在治疗与肾上腺皮质激素切除术相关的环状透析裂孔伴下垂性黄斑病变中的应用。
IF 0.9
International Medical Case Reports Journal Pub Date : 2024-05-27 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S469028
Masato Matsuo, Sho Ichioka, Akiko Harano, Yuji Takayanagi, Masaki Tanito
{"title":"Minimally Invasive Direct Internal Cyclopexy in the Management of Goniotomy-Related Cyclodialysis Cleft with Hypotony Maculopathy.","authors":"Masato Matsuo, Sho Ichioka, Akiko Harano, Yuji Takayanagi, Masaki Tanito","doi":"10.2147/IMCRJ.S469028","DOIUrl":"10.2147/IMCRJ.S469028","url":null,"abstract":"<p><strong>Introduction: </strong>Although ab-interno trabeculotomy-related (goniotomy-related) surgeries has a favorable safety profile, cyclodialysis cleft refractory to conservative management could occur, thereby requiring additional surgical treatment. External and, more recently, internal cycloplexy have been attempted to treat cyclodialysis clefts with hypotony maculopathy, however the traditional methods require conjunctival or scleral incisions and have been inappropriate for glaucoma patients who need to undergo future trabeculectomy. Therefore, we report two cases who underwent a novel reliable technique for suture fixation of the detached ciliary body onto the original scleral bed directly through the intraocular approach without conjunctival or scleral incision, minimally invasive direct internal cyclopexy, in the management of goniotomy-related cyclodialysis cleft with hypotony maculopathy.</p><p><strong>Case description: </strong>Goniotomy-related cyclodialysis cleft exceeded 45° and vision-threatening hypotony maculopathy was observed in two eyes in two patients with normal tension glaucoma and myopia gravis without a prior history of trauma who had undergone Kahook Dual Blade goniotomy combined with cataract surgery. The patients were followed conservatively for a while, however the cyclodialysis clefts and hypotony maculopathies did not resolve. Therefore, a 72-year-old man underwent minimally invasive direct internal cyclopexy on postoperative day 65 after the goniotomy, and another 67-year-old man underwent minimally invasive direct internal cyclopexy on postoperative day 149. In both cases, topical antibiotic and steroid eye drops were prescribed postoperatively. The cyclodialysis clefts were repaired successfully; however, the latter patient developed delayed-onset acute transient ocular hypertension 33 days after minimally invasive direct internal cyclopexy and required glaucoma medications. The hypotony maculopathies resolved approximately 3 months after suturing, and eventually visual acuity improved from preoperative levels and good intraocular pressure control was achieved in both. No further postoperative complications have been observed to date.</p><p><strong>Conclusion: </strong>We successfully managed two cases of goniotomy-related cyclodialysis cleft with hypotony maculopathy using minimally invasive direct internal cyclopexy.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11141708/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141199567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lessons to Learn About the Misdiagnosis of a Rare Case in China: Bart Syndrome or Carmi Syndrome? 中国罕见病例误诊的教训:巴特综合征还是卡尔米综合征?
IF 0.9
International Medical Case Reports Journal Pub Date : 2024-05-18 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S354337
Xiaoqing Wei, Junying Zhang, Youwen Mei, Eqiong Li, Qianling Dai, Xiaoli Yang, Dan Luo, Biao Li, Ping Hua, Jian Cai, Hua Lai, Dongfeng Qi, Sha Lai, Mi Qin, Yonghong Lin
{"title":"Lessons to Learn About the Misdiagnosis of a Rare Case in China: Bart Syndrome or Carmi Syndrome?","authors":"Xiaoqing Wei, Junying Zhang, Youwen Mei, Eqiong Li, Qianling Dai, Xiaoli Yang, Dan Luo, Biao Li, Ping Hua, Jian Cai, Hua Lai, Dongfeng Qi, Sha Lai, Mi Qin, Yonghong Lin","doi":"10.2147/IMCRJ.S354337","DOIUrl":"10.2147/IMCRJ.S354337","url":null,"abstract":"<p><strong>Objective: </strong>We report a case of Carmi Syndrome in a neonate.</p><p><strong>Aim: </strong>To share our lessons in diagnosis of the case of Carmi Syndrome.</p><p><strong>Case report: </strong>Carmi Syndrome is an extremely rare autosomal recessive genetic disorder characterized the coexistence of pyloric atresia and junctional epidermolysis bullosa, and with aplasia cutis congenita in approximately 28% patients. In this case, a full-term male neonate was born to a G<sub>4</sub>P<sub>2</sub><sup>+1</sup>L<sup>1</sup> multipara through cesarean section delivery in hospital in a non-consanguineous marriage with 4000mL of II°meconium-stained amniotic fluid. He was found extensive skin loss over lower legs and other parts, with scattered blisters and bilateral microtia. Plain abdominal X-ray revealed a large gastric air bubble with no gas distally. The mother had an intrauterine fetal loss previously for reasons unknown. The dermatologist diagnosed the newborn with Bart Syndrome, while the pediatric surgeon diagnosed congenital pyloric atresia(CPA). The parents refused further treatment and the neonate passed away about 30 hours after birth.</p><p><strong>Outcome: </strong>The neonate passed away about 30 hours after birth.</p><p><strong>Conclusion: </strong>Lessons from this case:①.Rule out Carmi Syndrome in patients with PA, and differentiate Bart syndrome and Carmi Syndrome in patients with abnormal skin manifestations. ②. For rare and/or severe diseases, multidisciplinary teams(MDTs) should be establish. ③. Genetic counseling and prenatal diagnosis are necessary prior to subsequent childbearings. ④.Termination of pregnancy might be contemplated if certain indicators are revealed.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11114136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141087449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complex Regional Pain Syndrome in Cancer Cases: Current Knowledge and Perspectives. 癌症病例中的复杂区域疼痛综合征:当前知识与展望
IF 0.9
International Medical Case Reports Journal Pub Date : 2024-05-18 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S451291
Chanon Thanaboriboon, Márcia C Matos Macêdo, Jordi Perez
{"title":"Complex Regional Pain Syndrome in Cancer Cases: Current Knowledge and Perspectives.","authors":"Chanon Thanaboriboon, Márcia C Matos Macêdo, Jordi Perez","doi":"10.2147/IMCRJ.S451291","DOIUrl":"10.2147/IMCRJ.S451291","url":null,"abstract":"<p><strong>Background: </strong>Complex regional pain syndrome (CRPS) is a disabling painful disorder caused by many different and poorly understood mechanisms. It often affects the distal limbs and usually happens as consequence of a trauma. Its severity can remarkably affect patients' quality of life. When this painful complication happens in a cancer patient, the impact may be exponential. To date, there is limited knowledge of the surrounding circumstances of CRPS cases in this population.</p><p><strong>Methods: </strong>We present two clinical cases of patients diagnosed with cancer-related pain presenting with symptoms and signs compatible with CRPS. In one case, CRPS was attributed to direct tumor nerve compression, and it responded successfully to an interventional pain procedure. The second case was associated with a Zoster infection in an immunocompromised cancer patient. Patient responded to multidisciplinary pain management strategies. Additionally, we conducted a literature review to investigate the coexistence of cancer pain and CRPS and suggest some pathophysiology mechanisms of action.</p><p><strong>Results and discussion: </strong>Literature reviewed and potential pathophysiology mechanisms are simultaneously explored in terms of classification, etiopathology, evidence, challenges, and future scientific directions.</p><p><strong>Conclusion: </strong>Comorbid CRPS can impact negatively in cases of cancer pain by affecting their diagnosis and treatment. Further studies are necessary to elucidate how these two conditions present together and how they can be better addressed.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11110819/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141081437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management and Discussion of COVID-19 Related Tracheal Stenosis: A Single Center Retrospective Review. COVID-19 相关气管狭窄的处理和讨论:单中心回顾性研究
IF 0.9
International Medical Case Reports Journal Pub Date : 2024-05-08 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S436903
Alexander J Sweidan, Haron Y Anaim, Niral M Patel, Javier A Longoria
{"title":"Management and Discussion of COVID-19 Related Tracheal Stenosis: A Single Center Retrospective Review.","authors":"Alexander J Sweidan, Haron Y Anaim, Niral M Patel, Javier A Longoria","doi":"10.2147/IMCRJ.S436903","DOIUrl":"10.2147/IMCRJ.S436903","url":null,"abstract":"<p><p>SARS-CoV-2 virus has led to an unprecedented amount of tracheal stenosis. Rigid bronchoscopy can serve as a curative measure or bridge therapy to tracheal resection. We also briefly discuss the pathophysiology of tracheal stenosis from prolonged intubation and SARS-CoV-2 virus. This should be differentiated from other forms of airway obstruction such as tracheobronchomalacia which would be considered a pseudo-tracheal stenotic disease. The aim of this study is to evaluate stenosis that is unable to be improved with positive airway pressure or \"PAP\" therapies and required stenting and/or subsequent tracheal resection. By performing Rigid Bronchoscopy and subsequent stenting of airways, we demonstrated outcomes for long term airway patency regarding patients who were intubated secondary to the SARS-CoV-2 virus. We demonstrate superb outcomes in a consecutive case series of 6 patients managed with rigid bronchoscopy, airway stent and tracheal resection. The patients were all managed from a pulmonary perspective by the physicians mentioned in this study.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11088833/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140911417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Point-of-Care Ultrasound to Assess Diaphragmatic Paralysis in Resource-Limited Setting: A Case Series. 在资源有限的环境中利用护理点超声波评估膈肌麻痹:病例系列。
IF 0.9
International Medical Case Reports Journal Pub Date : 2024-05-08 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S454708
Abduleazize Hussen, Menbeu Sultan, Muluneh Tufa Kidane, Melaku Getachew, Temesgen Beyene Abicho, Selome F Yewedalsew, Getaw Worku Hassen
{"title":"Point-of-Care Ultrasound to Assess Diaphragmatic Paralysis in Resource-Limited Setting: A Case Series.","authors":"Abduleazize Hussen, Menbeu Sultan, Muluneh Tufa Kidane, Melaku Getachew, Temesgen Beyene Abicho, Selome F Yewedalsew, Getaw Worku Hassen","doi":"10.2147/IMCRJ.S454708","DOIUrl":"10.2147/IMCRJ.S454708","url":null,"abstract":"<p><p>Diaphragmatic dysfunction can arise from various factors, and Guillain-Barre syndrome, characterized by acute inflammatory polyradiculoneuropathy, is one such cause that may result in respiratory failure due to diaphragmatic paralysis. Prompt recognition and timely intervention, including airway protection and addressing the underlying pathology, are crucial for achieving optimal patient outcomes. Point-of-care ultrasound, specifically utilizing the M-mode function, can be employed for individuals displaying symptoms of diaphragmatic paralysis. This diagnostic approach is uncomplicated an effective tool for serial follow-up. In this context, we present a case series involving three patients with diaphragmatic paralysis in a limited-resource setting.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11088823/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140911557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two Consecutive Ruptured Tubal Ectopic Pregnancies after Interval Bilateral Tubal Ligation. 双侧输卵管间隔结扎术后连续两次输卵管破裂异位妊娠
IF 0.9
International Medical Case Reports Journal Pub Date : 2024-05-08 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S463007
Moses Owiny, Monica Okwir Acen, Joram Okeng, Oliver Anyeko Akello
{"title":"Two Consecutive Ruptured Tubal Ectopic Pregnancies after Interval Bilateral Tubal Ligation.","authors":"Moses Owiny, Monica Okwir Acen, Joram Okeng, Oliver Anyeko Akello","doi":"10.2147/IMCRJ.S463007","DOIUrl":"10.2147/IMCRJ.S463007","url":null,"abstract":"<p><strong>Background: </strong>Bilateral tubal ligation (BTL) is an effective permanent method of birth control that is surgically performed to block the woman's fallopian tube and prevent the egg from meeting the sperm. It is preferred by women or couples who have achieved their reproductive potential and do not desire pregnancy. BTL carries a low risk of method failure with a subsequent pregnancy which is likely to be ectopic. We present a case of two consecutive ruptured tubal ectopic pregnancies following an interval BTL.</p><p><strong>Case presentation: </strong>A 40-year-old female, with 7 living children, who previously underwent an interval BTL, presented with acute abdominal pain for 2 days and amenorrhea for 6 weeks. She was stable but had generalized abdominal tenderness, guarding and rebound tenderness, and cervical motion tenderness. Her urine HCG was positive, and a trans-abdominal ultrasound scan revealed a tender echo-complex right adnexal mass, free fluid in the Cul-de-sac, and an empty uterine cavity, consistent with a ruptured right ectopic pregnancy. An emergency exploratory laparotomy was done with findings of a ruptured right distal tube containing products of conception, hemoperitoneum, and previous tubal ligation and left salpingectomy. A right total salpingectomy was done, and the excised right tube containing the mass was sent for histological examination, which revealed chorionic villi and hemorrhagic vascular decidual tissue in the fallopian tube, features suggestive of tubal ectopic pregnancy.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11088843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140911661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case Report and Literature Review of Acute Spontaneous Intraspinal Epidural Hematoma (SSEH) Secondary to Myeloproliferative Disease. 继发于骨髓增生性疾病的急性自发性椎管内硬膜外血肿 (SSEH) 的病例报告和文献综述。
IF 0.9
International Medical Case Reports Journal Pub Date : 2024-05-03 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S459679
Qinghao Liu, Weiwen Zhao, Hao Yin
{"title":"Case Report and Literature Review of Acute Spontaneous Intraspinal Epidural Hematoma (SSEH) Secondary to Myeloproliferative Disease.","authors":"Qinghao Liu, Weiwen Zhao, Hao Yin","doi":"10.2147/IMCRJ.S459679","DOIUrl":"10.2147/IMCRJ.S459679","url":null,"abstract":"<p><strong>Background: </strong>Spontaneous spinal epidural hematoma (SSEH) presenting in the context of JAK2 V617F-positive myeloproliferative neoplasms is a rare condition, characterized by the compression of the spinal cord leading to various symptoms. The etiology, pathogenesis, and optimal treatment strategies for this condition remain undetermined. The occurrence of spontaneous spinal epidural hematoma (SSEH) in the context of JAK2 V617F-positive myeloproliferative neoplasms (MPNs) represents a rare manifestation. Magnetic Resonance Imaging (MRI) plays a crucial role in the definitive diagnosis of this condition. With a good understanding of the pathogenic characteristics and clinical presentations of this disease, a diagnosis can be reasonably made, even in the absence of MRI, based on physical examinations indicating the affected area. Once diagnosed, immediate surgery is recommended to attempt the restoration of spinal cord function. Postoperatively, the use of hydroxyurea has proven effective in disease control.</p><p><strong>Case presentation: </strong>We report a case of a 65-year-old male patient who presented with progressive lumbar back pain and bilateral lower limb paralysis lasting for 36 hours. CT imaging revealed an intraspinal lesion at the L1-3 level, and genetic testing confirmed the presence of the JAK2V617F mutation. Following surgery, there was a significant recovery of sensory and motor function in the lower limbs. At one-year follow-up, the patient demonstrated good functional status, and blood tests indicated a platelet count within the normal range.</p><p><strong>Conclusion: </strong>The presented case adds to the existing literature on SSEH by highlighting the association with myeloproliferative neoplasms (MPNs), as evidenced by the JAK2V617F mutation. MPNs constitute a group of hematologic malignancies, and the association with SSEH is a rare occurrence. The exact interplay between MPNs and SSEH warrants further investigation, as the underlying mechanisms linking these conditions remain elusive. The case also underscores the importance of a multidisciplinary approach, involving hematologists and neurosurgeons, in the comprehensive management of such complex cases.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11077292/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140892029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Giant Thyroid Gland Abscess Causing Upper Airway Obstruction: A Case Report. 巨大甲状腺脓肿导致上气道阻塞:病例报告
IF 0.9
International Medical Case Reports Journal Pub Date : 2024-05-03 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S458035
Dagmawi Anteneh Teferi, Ayto Addisu Negash, Daniel Aman, Sisay Hailu, Taye Nigatu Tola, Yared G/Michael Tarekegn, Wubhareg Anteneh Teferi
{"title":"Giant Thyroid Gland Abscess Causing Upper Airway Obstruction: A Case Report.","authors":"Dagmawi Anteneh Teferi, Ayto Addisu Negash, Daniel Aman, Sisay Hailu, Taye Nigatu Tola, Yared G/Michael Tarekegn, Wubhareg Anteneh Teferi","doi":"10.2147/IMCRJ.S458035","DOIUrl":"10.2147/IMCRJ.S458035","url":null,"abstract":"<p><strong>Background: </strong>Thyroid gland abscess is a rare pathology with life-threatening complications when there is a delay in diagnosis. However, physicians should be aware of and consider this differential in patients with anterior neck swelling having acute onset compressive symptoms to ensure early diagnosis and management.</p><p><strong>Case presentation: </strong>A 62-year-old female patient presenting with worsening of painful anterior neck swelling with associated fever, shortness of breath, and difficulty swallowing. The patient was found to have a thyroid abscess causing upper airway obstruction, against a background of follicular nodular disease found on clinical examination, cytology and fluid analysis from aspirate, biopsy, ultrasonography, and computed tomography. The patient was managed with endotracheal intubation and was subsequently discharged after recovery with antibiotic therapy, incision and drainage, and thyroid lobectomy.</p><p><strong>Conclusion: </strong>Thyroid abscess is an uncommon, critical clinical condition with high morbidity and mortality. Thyroid gland abscess should be considered while evaluating patients presenting with acute onset anterior neck swelling. Satisfactory clinical outcomes could be achieved with early diagnosis and proper management.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11075674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140876431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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