International Medical Case Reports Journal最新文献

{"title":"Neonatal Gastric Perforation Temporally Associated with Nasogastric Tube Insertion: A Case Report.","authors":"Shukri Said Mohamed, Omar Adam Sheikh, Ahmet Sarac, Abdisamad Omar Ali, Abdirahman Ahmed Mohamud, Abdullahi Ali Moallim Hussien","doi":"10.2147/IMCRJ.S632789","DOIUrl":"https://doi.org/10.2147/IMCRJ.S632789","url":null,"abstract":"<p><strong>Background: </strong>Neonatal gastric perforation (NGP) is a rare but potentially life-threatening condition associated with substantial morbidity and mortality. Approximately half of reported cases are idiopathic or spontaneous, while the remainder are attributed to identifiable causes, including congenital gastric wall defects, hypoxic-ischemic injury, and iatrogenic trauma related to nasogastric tube (NGT) insertion, particularly in premature and low-birth-weight infants. Early diagnosis and prompt surgical intervention are critical for improving outcomes. We report a case of gastric perforation temporally associated with nasogastric tube insertion in a preterm, small-for-gestational-age (SGA) neonate, highlighting the diagnostic challenge of distinguishing mechanical from ischemic etiologies, together with management and preventive considerations.</p><p><strong>Case presentation: </strong>We describe a male preterm neonate, born at 34 weeks of gestation with a birth weight of 1.5 kg (small for gestational age), who developed acute abdominal distension and respiratory distress approximately 12 hours after nasogastric tube placement for enteral feeding. Abdominal radiography revealed significant pneumoperitoneum, indicating gastrointestinal perforation. Emergency exploratory laparotomy confirmed a 1-cm full-thickness gastric perforation along the greater curvature of the stomach. The perforation was repaired surgically, and the infant subsequently recovered with comprehensive postoperative intensive care management.</p><p><strong>Conclusion: </strong>Clinicians should maintain a high index of suspicion for gastric perforation in neonates, particularly those born preterm or small for gestational age, who develop rapid abdominal distension, pneumoperitoneum, or signs of sepsis following nasogastric tube insertion. Because clinical and radiological findings alone often cannot reliably distinguish mechanical from ischemic causes, standardized insertion protocols, prompt radiological evaluation, and timely surgical intervention remain essential for improving survival and outcomes in this rare but serious condition.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"19 ","pages":"632789"},"PeriodicalIF":0.7,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13633743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delayed Recognition of a Cuff-Level Tracheal Rupture After Double-Lumen Endotracheal Tube Intubation for Thoracic Surgery: A Case Report.","authors":"JongHyun Baek, Min Gang Kwon, Eun Kyung Choi","doi":"10.2147/IMCRJ.S648349","DOIUrl":"https://doi.org/10.2147/IMCRJ.S648349","url":null,"abstract":"<p><strong>Background: </strong>Double-lumen endotracheal tubes (DLTs) are widely used to facilitate one-lung ventilation during thoracic surgery and are generally considered safe. However, tracheobronchial rupture is a rare but potentially life-threatening complication. Injuries occurring at the tracheal cuff level may initially remain clinically occult because the inflated cuff can obscure the injured area during bronchoscopic examination.</p><p><strong>Case presentation: </strong>An 81-year-old man underwent left upper lobectomy for lung adenocarcinoma using a left-sided DLT. The procedure was converted from VATS to an anterolateral mini-thoracotomy because of persistent diffuse oozing. Ten hours postoperatively, he required emergent reoperation for intrathoracic bleeding. Persistent air leakage, left lung atelectasis, and progressive subcutaneous emphysema subsequently developed. Bronchoscopy on postoperative day (POD) 6 demonstrated a posterolateral tracheal wall defect at the membranous-cartilaginous junction, estimated to measure at least 1-1.5 cm. Exact measurement was limited by oxygen desaturation. Initial conservative management was undertaken; however, the air leak and failure of lung re-expansion persisted. Repeat bronchoscopy on POD12 showed no appreciable improvement in the defect and confirmed that the defect was located approximately 5 cm above the carina. Definitive surgical repair was performed through a left thoracotomy on POD13. The defect was primarily closed using 4-0 Prolene sutures, and intraoperative bronchoscopy and air-leak testing confirmed closure.</p><p><strong>Conclusion: </strong>Tracheal cuff injuries after DLT intubation may initially remain undetected. Persistent postoperative air leakage, subcutaneous emphysema, or failure of lung re-expansion should prompt early bronchoscopic evaluation, with careful inspection of the tracheal cuff level.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"19 ","pages":"648349"},"PeriodicalIF":0.7,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13633767/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refractory Acquired Thrombotic Thrombocytopenic Purpura in the Third Trimester of Twin Pregnancy: A Case Report.","authors":"Jeya Sushimitha Jawahar Kanth, Morrish Obol Okello, Thuparambil M Ravi Anish, Micheal Collins Segawa, Herbert Kayiga, Sheethal Madari","doi":"10.2147/IMCRJ.S629280","DOIUrl":"https://doi.org/10.2147/IMCRJ.S629280","url":null,"abstract":"<p><strong>Background: </strong>Acquired thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening condition triggered by pregnancy, often in the third trimester, and frequently mimics preeclampsia or HELLP syndrome due to shared features like thrombocytopenia. Refractory cases in twin pregnancies, described in this case, pose unique diagnostic and therapeutic challenges, requiring advanced interventions.</p><p><strong>Case presentation: </strong>A 29-year-old woman carrying dichorionic-diamniotic twins presented in the third trimester with palpitations, dyspnea, oral bleeding, numbness, chest heaviness, fatigue, edema, and pelvic pain. Admission showed severe thrombocytopenia (8 × 10⁹/L), microangiopathic hemolytic anemia (schistocytes, elevated LDH), normal blood pressure, and normal liver/kidney function, making preeclampsia/HELLP unlikely. Because of the high bleeding risk posed by the profound thrombocytopenia, and despite a reassuring fetal assessment, an emergency cesarean section was performed and delivered two healthy baby girls with good Apgar scores. ADAMTS13 activity <10% subsequently confirmed acquired TTP. Plasma exchange and corticosteroids were started presumptively on the day of admission; because the platelet response was incomplete, rituximab and caplacizumab were added during the same admission. The patient was discharged after initial hematologic recovery but relapsed with recurrent severe thrombocytopenia three days later, confirming refractory disease; she was readmitted and achieved sustained platelet normalization with continued plasma exchange, rituximab, and caplacizumab. Complications included wound infection with multiple organisms, antibiotic allergy, and superficial venous thrombosis, all managed successfully. Both mother and infants were discharged well, with no further relapse at six-week follow-up. Future pregnancies were discouraged without specialist review.</p><p><strong>Conclusions: </strong>High suspicion for TTP is essential in pregnant patients with thrombocytopenia and hemolysis, even without hypertension. Rapid ADAMTS13 testing, timely delivery, and combined plasma exchange with rituximab and caplacizumab enabled full recovery in this refractory twin-pregnancy case. Multidisciplinary care is critical to differentiate from obstetric mimics and achieve favorable outcomes.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"19 ","pages":"629280"},"PeriodicalIF":0.7,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13633768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Challenges in mNGS for Pulmonary Mucormycosis Presenting with Imaging Features Resembling Those of Lung Cancer.","authors":"Huajun Yang, Xi Lei","doi":"10.2147/IMCRJ.S616885","DOIUrl":"https://doi.org/10.2147/IMCRJ.S616885","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary mucormycosis is a rare fungal infection with an increasing incidence in clinical reports. Its non-specific presentation often mimics lung cancer, posing significant diagnostic challenges. This report aims to improve clinician recognition of this condition.</p><p><strong>Case presentation: </strong>A 67-year-old woman with diabetes presented with cough and sputum production. Imaging revealed a right hilar mass with bronchial obstruction, mediastinal lymphadenopathy, and cystic cavities (Figure 1A). While initial suspicion favored lung cancer, metagenomic next-generation sequencing (mNGS) of bronchoalveolar lavage fluid (BALF) detected <i>Rhizopus oryzae</i> (26,879 sequences), prompting revision of the diagnosis. Antifungal therapy with amphotericin B and posaconazole resulted in clinical improvement. Follow-up imaging at 67 days showed resolution of mucormycosis (Figure 1B).</p><p><strong>Conclusion: </strong>This case highlights the diagnostic challenge of pulmonary mucormycosis masquerading as malignancy. mNGS serves as a valuable tool for early pathogen identification, though its role in therapeutic monitoring requires further investigation.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"19 ","pages":"616885"},"PeriodicalIF":0.7,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13632618/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent Juvenile Nasopharyngeal Angiofibroma: Two Cases Emphasizing the Role of Follow-Up and Staging in Surgical Planning.","authors":"Mukhammadbektosh Khaydarov, Murod Khudayorov, Khusniddin Nazarov, Otabek Abdurakhmonov","doi":"10.2147/IMCRJ.S606905","DOIUrl":"https://doi.org/10.2147/IMCRJ.S606905","url":null,"abstract":"<p><strong>Background: </strong>Juvenile nasopharyngeal angiofibroma (JNA) is a rare, benign but locally aggressive vascular tumor affecting adolescent males. While endoscopic resection with preoperative embolization remains the treatment of choice, recurrence remains a challenge, often driven by incomplete excision or poor follow-up adherence.</p><p><strong>Case presentation: </strong>We report two cases of recurrent JNA in adolescent males, each highlighting a different modifiable risk factor for recurrence. Case 1 involved a 21-year-old with prior resection and poor postoperative follow-up, who re-presented with Radkowski Stage IIIA disease involving the central skull base. Case 2 involved an 18-year-old initially misdiagnosed with a nasal polyp, later confirmed as JNA after recurrence within 4 months of surgery. Both patients underwent preoperative embolization followed by endoscopic endonasal resection using a transnasal-transpterygoid approach. Histopathology confirmed recurrent JNA in both cases. Postoperative MRI at 3 months showed no evidence of residual or recurrent disease.</p><p><strong>Conclusion: </strong>These cases underscore the critical role of accurate initial diagnosis, proper staging, and structured postoperative surveillance in reducing recurrence risk in JNA. Multidisciplinary care, patient education, and imaging-guided follow-up protocols are essential, especially in resource-constrained settings where diagnostic delays and adherence challenges are prevalent.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"19 ","pages":"606905"},"PeriodicalIF":0.7,"publicationDate":"2026-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13625996/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Case of a Molar Pregnancy Coexisting with a Live Foetus in a Patient with Prior Exposure to M-2 Tone in First Trimester in Eastern Uganda: A Case Report.","authors":"Julius Nteziyaremye, Stephen Waiswa","doi":"10.2147/IMCRJ.S607601","DOIUrl":"https://doi.org/10.2147/IMCRJ.S607601","url":null,"abstract":"<p><strong>Introduction: </strong>Although gestational trophoblastic diseases (GTD) is common, its coexistence with a viable twin pregnancy is a rare phenomenon. The occurrence of such a pregnancy, with reports of prior exposure to M2-tone in early pregnancy, has not been documented before. To the best of our knowledge, this is the first of such a case in Uganda.</p><p><strong>Case: </strong>A 30 years old, black African Ugandan, gravida 3para 1+1 at 19⁺⁴ weeks of amenorrhoea (WOA) presented at Mbale RegionalReferral Hospital (MRRH) in September 2024. She had had a viable term vaginal delivery 5 years ago, that was followed by secondary infertility, for which, no treatment was sought. She subsequently had two natural conceptions. The second pregnancy was lost at 3 months of amenorrhoea following a spontaneous abortion. During the current pregnancy, she was put on M-2 tone (Ayurveda tablets) for 2 months and oral progesterone 10 mg daily till 12 weeks of amenorrhoea. During her fourth antenatal care (ANC) contact, it was noticed that she had gained excessive weight for the WOA. Further assessment revealed exaggerated symphysio-fundal height (SFH). The obstetric scan requested for showed features of viable foetus coexisting with a molar pregnancy. Three prior ultrasound scans had apparently reported a normal pregnancy. Serum beta human chorionic gonadotrophin hormone was very high for WOA. During the pregnancy and peripartum period, she developed obstetric complications but delivered a viable foetus, with a placenta that showed clinical evidence of molar pregnancy. Follow up has revealed resolution of symptoms and no gestational trophoblastic neoplasia (GTN) sequelae.</p><p><strong>Conclusion: </strong>Molar twin pregnancy with a viable foetus is associated with various maternal and perinatal adverse outcomes and presents management challenges. Whether early pregnancy exposure to M2-tone is a risk factor cannot be elucidated. Close antenatal and postnatal surveillance should be instituted to rule out GTN sequelae.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"19 ","pages":"607601"},"PeriodicalIF":0.7,"publicationDate":"2026-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13627285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced Eumycetoma of the Right Foot Resulting in Below-Knee Amputation in Somalia: A Case Report.","authors":"Mohamed Adam Mahamud, Mohamed Mustaf Ahmed, Shafie Abdulkadir Hassan, Ismail Mohamoud Abdullahi, Mohamed Abdullahi Omar, Mohamed Ali Kahiye, Wendy W J Van de Sande, Tigad Abdisad Ali, Emmanuel Edwar Siddig","doi":"10.2147/IMCRJ.S633948","DOIUrl":"10.2147/IMCRJ.S633948","url":null,"abstract":"<p><strong>Introduction: </strong>Mycetoma is a chronic, progressively destructive neglected tropical disease that presents with localised swelling, multiple sinus tracts and a discharge containing grains, and that may extend into deep tissue and bone. Somalia lies within the recognised mycetoma belt, but the national burden is poorly documented, and few patients reach specialist care early enough for the limb to be saved.</p><p><strong>Case presentation: </strong>A 33-year-old man from Qoryooley District, Lower Shabelle, Somalia, presented with a seven-year history of progressive swelling of the right foot. Examination showed massive tumefaction and multiple discharging sinuses containing black grains. Magnetic resonance imaging demonstrated extensive soft-tissue destruction, sinus tracts, tendon involvement and osteomyelitis of several tarsal and metatarsal bones. Histopathological examination confirmed eumycetoma. Specialised fungal culture and molecular testing were not available at the institution, so the causative species could not be identified. Because the extent of soft-tissue destruction and multi-bone involvement left no viable limb-sparing option, a right below-knee amputation was performed, followed by oral itraconazole planned for twelve months. At three months the stump had healed with no clinical evidence of recurrence, and the patient continued antifungal treatment and rehabilitation.</p><p><strong>Conclusion: </strong>Delayed diagnosis of eumycetoma can cost the patient a limb. Magnetic resonance imaging determined management here by mapping the extent of disease and showing that limb-sparing surgery was no longer feasible. Earlier referral, and better access to imaging, mycological diagnosis and antifungal treatment, would spare other patients in Somalia the same outcome.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"19 ","pages":"633948"},"PeriodicalIF":0.7,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13618569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149074573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant Mesenteric Cyst: A Case Series.","authors":"Omar Adam Sheikh, Shukri Said Mohamed, Ahmet Sarac, Abdisamad Omar Ali, Abdullahi Ali Moallim Hussien","doi":"10.2147/IMCRJ.S632963","DOIUrl":"10.2147/IMCRJ.S632963","url":null,"abstract":"<p><strong>Introduction: </strong>Mesenteric cysts are rare benign intra-abdominal lesions that can present with a wide spectrum of clinical manifestations. They are most commonly located within the mesentery of the small intestine and are less frequently found in the mesocolon. Because their clinical presentation varies according to the size and location of the cyst, symptoms are often nonspecific, making diagnosis challenging.</p><p><strong>Case presentation: </strong>We report two pediatric cases of mesenteric cysts. The first case involved a 10-month-old male infant who presented with abdominal distension and intermittent non-bilious vomiting. The second case involved a 5-year-old boy who presented with severe abdominal distension caused by a large intra-abdominal mass and was subsequently referred to the Pediatric Surgery Department. Following clinical evaluation and preoperative investigations, both patients were diagnosed with mesenteric cysts and underwent surgical excision. The resected cysts were submitted for histopathological examination, which confirmed the diagnosis. Both patients had an uneventful postoperative recovery, with no complications or recurrence observed during follow-up.</p><p><strong>Clinical discussion: </strong>Mesenteric cysts are exceedingly rare, with an estimated incidence of approximately 1 per 250,000 hospital admissions. They may occur at any age but are uncommon in children. Most mesenteric cysts remain asymptomatic and are discovered incidentally during radiological investigations or surgical procedures. Clinical symptoms typically develop when the cyst enlarges sufficiently to cause compression of adjacent structures, resulting in abdominal distension, pain, vomiting, or intestinal obstruction.</p><p><strong>Conclusion: </strong>We present two pediatric cases of mesenteric cysts to highlight the importance of considering this rare entity in the differential diagnosis of abdominal masses and distension in children. Early diagnosis and complete surgical excision remain the cornerstone of successful treatment and are associated with excellent outcomes.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"19 ","pages":"632963"},"PeriodicalIF":0.7,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13620307/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149080850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Avulsion Fracture at the Femoral Origin of the Medial Head of the Gastrocnemius in an Adolescent: A Case Report with Two-Year Clinical Follow-Up.","authors":"Ammar K Alomran","doi":"10.2147/IMCRJ.S645263","DOIUrl":"10.2147/IMCRJ.S645263","url":null,"abstract":"<p><p>Avulsion fractures at the femoral origin of the medial head of the gastrocnemius are exceptionally rare, particularly in skeletally immature patients, and may be overlooked when evaluating acute posterior knee pain. A previously healthy 13-year-old boy developed acute posteromedial left knee pain and felt a sudden pop while running. He could bear weight with difficulty and held the knee in slight flexion because terminal extension was painful. Examination showed focal posteromedial tenderness, preserved motion with pain at full extension, and an intact distal neurovascular status. Plain radiographs demonstrated a small osseous fragment posterior to the distal femur. Magnetic resonance imaging (MRI) identified a 1.2 × 0.5 cm minimally displaced, partially corticated fragment arising from the femoral origin of the medial head of the gastrocnemius, with no associated ligamentous, meniscal, or musculotendinous injury. The patient was managed with a long-leg cast at 30° of knee flexion for six weeks, followed by six weeks of supervised range-of-motion, stretching, and strengthening exercises. He regained painless full range of motion, normal strength on clinical examination, and a stable knee, and subsequently returned to sports without reported pain or functional limitation. At two-year clinical follow-up, he remained asymptomatic without instability or treatment-related complications. This case adds to the limited pediatric literature on this uncommon injury and highlights the role of MRI in characterizing the lesion and excluding associated injuries. Because no follow-up imaging was obtained, the outcome represents clinical recovery rather than radiographically confirmed osseous union.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"19 ","pages":"645263"},"PeriodicalIF":0.7,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13616158/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149069710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolated Ovarian Tuberculosis Mimicking Ovarian Malignancy in a Young Female with Primary Infertility: A Case Report.","authors":"Mohammad Fahim Sarwary, Mahbobullah Sediqi, Mohammad Hussain Modabber, Mohammad Ibrahim Kamal, Amjadzia Bawarzai, Maiwand Marofi, Abdul Ghaffar Mukhlis, Latifa Sadeqy","doi":"10.2147/IMCRJ.S636922","DOIUrl":"10.2147/IMCRJ.S636922","url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis (TB) is an infectious disease that most commonly affects the lungs and remains among the top 10 causes of death worldwide. Isolated ovarian tuberculosis is a rare form of extrapulmonary TB that usually presents with atypical symptoms and infertility. It brings significant diagnostic challenges and may mimic ovarian malignancy.</p><p><strong>Case presentation: </strong>A 23-year-old nulliparous Afghan woman underwent laparotomy for suspected ovarian adnexal masses/ovarian tumor after presenting with pelvic pain, prolonged low-grade fever, and infertility for five years following marriage. Intraoperatively, bilateral ovarian cysts were noted; subsequently, bilateral cystectomies were done. Postoperative Histopathology of surgical specimens confirmed the diagnosis of tuberculosis lesions, and the patient was referred for anti-tuberculous therapy.</p><p><strong>Conclusion: </strong>Isolated ovarian tuberculosis can present as adnexal masses with elevated CA-125 and could closely mimic ovarian malignancy. This case highlights the need to consider ovarian tuberculosis in the differential diagnosis, particularly in endemic regions. It emphasizes the value of histopathological confirmation to prevent misdiagnosis and to recommend early initiation of antitubercular therapy for favorable clinical outcomes.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"19 ","pages":"636922"},"PeriodicalIF":0.7,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13616165/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149069671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}