International Medical Case Reports Journal最新文献

{"title":"A Dermatological Intervention of Gynecomastia in Young Asian Man with a History of Soy Product Consumption: A Case Report.","authors":"Reyhan Widjajahakim, Raymond Makmur Widjajahakim, Ketut Kwartantaya Winaya","doi":"10.2147/IMCRJ.S496803","DOIUrl":"https://doi.org/10.2147/IMCRJ.S496803","url":null,"abstract":"<p><p>Gynecomastia is an enlargement of the breasts in men, which is usually benign but can also manifest as a result of malignancies, and can be either unilateral or bilateral. Pseudogynecomastia is male breast enlargement due to excessive fat, while true gynecomastia is a proliferation of glandular tissue. Gynecomastia is common in infants, adolescents, and elderly men, with the most common cause is related to hormonal changes associated with aging. Medical intervention is usually required for true gynecomastia that has lasted more than a year. Here, we report a case of a 33-year-old Chinese-Indonesian decent with enlarged breasts. The patient reported frequent consumption of homemade soybean milk (1/2 to 1 liter daily) accompanied by bland chicken during his body-building regimen. The patient had discontinued the regimen and the diet for 2 years prior to the initial visit. During physical examination, both breasts were enlarged and had firm nodule, mobile, and attached at the sub-central areola mammae with a diameter of 8 cm. The patient was then diagnosed with true gynecomastia Simon degree 2A and Geschikter and Copeland type 3. As the gynecomastia had persisted longer than a year, a dermatological intervention was planned. Ultrasound-assisted liposuction was performed with a solid probe and glandular excision. Fat tissue was obtained, 130 mL from the right breast and 120 mL from the left breast. A dense 2.5 cm × 2.5 cm × 2 cm glandular tissue was obtained from both breasts. The patient was satisfied with the surgery outcome.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"173-179"},"PeriodicalIF":0.7,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11776416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eales' Disease in Inuit: A Short Report and Clinical Update.","authors":"Thomas Richard Johansen Forshaw, Birgitte Moldow","doi":"10.2147/IMCRJ.S505170","DOIUrl":"10.2147/IMCRJ.S505170","url":null,"abstract":"<p><strong>Purpose: </strong>We report a case of Eales disease in Inuit and reflect on advances in telemedicine and treatment of retinal disease since the first report of Eales' disease in Greenlandic Inuit was published.</p><p><strong>Patients and methods: </strong>A 41-year-old Inuit female complaining of blurred vision was referred to our eye department. There had been no sign of diabetic retinopathy during diabetic eye screening and the patient had been treated for tuberculosis in 2010. Telemedical assessment was suspicious for vitritis or vitreous hemorrhage in the right eye, and the patient was flown from Greenland to Denmark, where examination revealed mild vitritis in the right eye, vitreous hemorrhage in the left eye and retinal neovascularization in both eyes. Fundus fluorescein angiography showed vessel leakage and areas of retinal non-perfusion. There was left epiretinal membrane with retinal thickening on macular optical coherence tomography.</p><p><strong>Results: </strong>Based on the patient's clinical findings and history of tuberculosis infection, a diagnosis of Eales' disease was made. The left eye was treated with pars plana vitrectomy with epiretinal membrane peeling, endodiathermy and endolaser. The right eye was treated in outpatients with sectoral laser photocoagulation. At seven weeks' follow-up, the visual acuity had improved from 6/12 to 6/6 (right eye) and from 6/36 to 6/7.5 (left eye).</p><p><strong>Conclusion: </strong>The prevalence of tuberculosis in Greenland is very high and it is recommended that clinicians remain alert to the possibility of Eales' disease, as beneficial visual outcomes are associated with prompt diagnosis and treatment. Telemedicine allows more frequent follow-up of Greenlander patients.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"157-161"},"PeriodicalIF":0.7,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11771164/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implantation of Heparin-Conjugated Fibrin Hydrogel for Local Defects of Cartilage in Knee Osteoarthritis: A Case Report.","authors":"Tusipkhan Toktarov, Yerik Raimagambetov, Bagdat Balbossynov, Dina Saginova, Mukhtar Abilmazhinov, Vyacheslav Ogay","doi":"10.2147/IMCRJ.S483485","DOIUrl":"10.2147/IMCRJ.S483485","url":null,"abstract":"<p><strong>Background: </strong>Cartilage defects in the knee joint are areas of damage and wear to the cartilage that normally covers and protects the ends of bones. These defects occur due to sudden injuries, such as trauma or sports accidents, or due to chronic conditions, such as osteoarthritis. Cartilage acts as a shock absorber (cushion absorber), reducing the impact of mechanical stress on the joints, which helps prevent bone damage during movement. Cartilage also serves as a gliding surface for the joints, allowing them to move smoothly, which minimizes friction between the bones. Its damage can cause pain, swelling, and decreased joint function. Treatment of localized cartilage defects is important to prevent further damage to the joint and maintain good knee function. Identifying problems early and treating them correctly can help improve outcomes and reduce the likelihood of more serious joint problems.</p><p><strong>Case description: </strong>We describe the case of a 46-year-old man with a localized cartilage defect in the knee joint who was followed for one year after the application of heparin-conjugated fibrin hydrogel for the treatment. We watched the patient for a year, doing functional tests, checking MRI results after the procedure, and watching for side effects.</p><p><strong>Results: </strong>This case demonstrates that implantation of hydrogel successfully engraft and lead to remodeling of hyaline-like cartilage, thereby improving the condition of damaged knee cartilage. Comparison of MRI images before and 1 year after surgery showed the effectiveness of this technology.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"151-156"},"PeriodicalIF":0.7,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11769846/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of Vasa Previa Diagnosed at Term: Elective Caesarean Section with Good Feto-Maternal Outcomes.","authors":"Nathania Nathania, Jeffry Iman Gurnadi, Andi Rinaldi, Triana Rahmanita","doi":"10.2147/IMCRJ.S459911","DOIUrl":"10.2147/IMCRJ.S459911","url":null,"abstract":"<p><p>Vasa previa is a condition where unprotected fetal vessels, neither by placenta nor umbilical cord, lie within the membranes over the internal cervical ostium and beneath the presenting part of the fetus. Due to this condition, the membranous vessels pose a higher risk of being compressed or ruptures and could lead to fetal demise, exsanguination, or even fetal death. In this case report, we reported a case of a 36-year-old woman, G3P2A0, at term gestation and oblique lie. Early prenatal diagnosis using transvaginal ultrasound could increase the survival rate of the fetus if followed by sufficient management after diagnosis. Caesarean birth is the safest mode of delivery even before the clinical signs or onset of labor occur.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"145-150"},"PeriodicalIF":0.7,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypothyroidism Due to Thyroid Amyloidosis Simultaneously With AL Renal Amyloidosis to Give Better Idea of Association of the Two Conditions.","authors":"Changrong Guan, Yonghua Liu, Riqiu Chen, Yingbiao Zhu","doi":"10.2147/IMCRJ.S489760","DOIUrl":"10.2147/IMCRJ.S489760","url":null,"abstract":"<p><p>Primary amyloidosis (AL type) is a systemic disease that can lead to structural and functional damage to organs and tissues such as the kidney, heart and liver with non-specific symptoms. Most of the affected patients develop thyroid infiltration and thus diffuse enlargement of the thyroid gland, while cases leading to hypothyroidism are exceedingly rare. Some researchers have analyzed thyroid function in newly diagnosed patients with AL amyloidosis, and found that the incidence of overt hypothyroidism is only 7%. In this case, we describe a 66-year-old female patient who visited the nephrology department due to lower limb edema for 2 months and numbness of the extremities for more than 2 years. Examination revealed massive proteinuria and hypoproteinemia, and a needle biopsy of the kidney revealed amyloid deposition. The patient was also found to have hypothyroidism and diffuse enlargement of the thyroid gland. We evaluated the etiology of thyroid disease from the pathogenesis of the disease after consulting an endocrinologist. The result of the thyroid fine needle puncture and pathological examination showed thyroid amyloidosis. The patient received levothyroxine sodium tablets as replacement therapy and received chemotherapy in the hematology department. At the same time, we monitored the improvement in thyroid function and reduction in thyroid volume.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"139-144"},"PeriodicalIF":0.7,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758865/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Mechanical Thrombectomy for Bilateral Anterior Cerebral Artery Occlusions in a Rare Anatomical Variant: A Case Report.","authors":"Beihai Ge, Jianjian Zhu, Fu Zhang, Xianyan Han, Yaqian Xia, Zeqiang Ji, Peili Sun, Yuqing Li, Huiying Zhang, Jianghong Guo","doi":"10.2147/IMCRJ.S504211","DOIUrl":"10.2147/IMCRJ.S504211","url":null,"abstract":"<p><strong>Background: </strong>Acute ischemic stroke (AIS) is usually caused by acute occlusion of the cerebral artery. Bilateral anterior cerebral arteries (ACAs) originating from the anterior communicating branch of the same internal carotid artery are a rare anatomical variation in clinical practice. Mechanical thrombectomy (MT) of simultaneous acute occlusion of the bilateral ACAs with this variation has rarely been reported.</p><p><strong>Case presentation: </strong>A 49-year-old man was referred for sudden onset of right-side weakness and aphasia for almost 55 min. AIS was considered after no bleeding was observed on emergency head computed tomography. Digital subtraction angiography was performed, and bilateral ACAs were found to originate from the anterior communicating branch of the left internal carotid artery and were occluded in their A2 segment. After immediate emergency MT with a stent retriever, the symptoms obviously improved.</p><p><strong>Conclusion: </strong>Simultaneous acute occlusion of the bilateral ACAs originating from the anterior communicating branch of the same internal carotid artery is rare in clinical practice. For such patients, MT with a stent retriever is feasible even if there is a risk of thrombectomy escape, and a stent retriever with aspiration or a direct aspiration technique may be more appropriate.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"125-129"},"PeriodicalIF":0.7,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758864/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Central Corneal Subepithelial Haze Following Keratoplasty With Interrupted Sutures: A Novel Clinical Finding.","authors":"Omar Kirat, Rawan Hawsawi, Sara AlHilali","doi":"10.2147/IMCRJ.S504331","DOIUrl":"10.2147/IMCRJ.S504331","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to describe a newly identified clinical finding of central corneal subepithelial haze following keratoplasty (both penetrating and lamellar) with interrupted sutures, and to explore its causes and management strategies.</p><p><strong>Methods: </strong>Case series.</p><p><strong>Results: </strong>The study included 7 males and 3 females, with an average age of 24.89 ± 6.57 years. Eight eyes underwent lamellar keratoplasty, and two underwent penetrating keratoplasty. Subepithelial haze appeared between 2 and 5 months postoperatively, associated with central corneal steepening. The mean BCVA improved from 0.88 ± 0.50 logMAR preoperatively to 0.51 ± 0.20 at haze documentation and 0.50 ± 0.16 after haze resolution. Selective suture removal resulted in haze resolution in 9 eyes, while delayed intervention in one case led to permanent scarring.</p><p><strong>Conclusion: </strong>Central corneal subepithelial haze following keratoplasty with interrupted sutures is linked to suture tension and central corneal steepening. Early suture adjustment or removal is essential to prevent permanent scarring. Further studies are needed to better understand this complication's pathophysiology.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"131-138"},"PeriodicalIF":0.7,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758859/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143046652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"X-Linked Autism Type 9 Caused by a Hemizygote Pathogenic Variant in the <i>TMLHE</i> Gene: Etiological Diagnosis in an Adult Male with Moderate Intellectual Disability.","authors":"Willem M A Verhoeven, Rolph Pfundt, Udo F H Engelke, Leo A J Kluijtmans, Jos I M Egger","doi":"10.2147/IMCRJ.S506204","DOIUrl":"10.2147/IMCRJ.S506204","url":null,"abstract":"<p><strong>Introduction: </strong>Levocarnitine is essential for brain functioning and fatty acid metabolism and stems largely from dietary sources. The Epsilon-Trimethyllysine Hydroxylase (<i>TMLHE</i>) gene encodes the enzyme N-Trimethyllysine hydroxylase (TMLH) which catalyses the first step in the biosynthesis of carnitine. Lack of TMLH enzyme activity is associated with developmental delay and autistic behaviours described as X-linked recessive autism, type 6 (OMIM#300872).</p><p><strong>Patient and methods: </strong>Here, an institutionalized adult male patient with intellectual disability, autism, and challenging behaviours is presented in whom genetic analysis disclosed a novel pathogenic variant in the <i>TMLHE</i> gene. Extensive somatic, neurological, psychiatric, and neuropsychological investigations were performed next to examination of hematological and biochemical parameters including plasma carnitine status. Also, Whole Exome Sequencing (WES) and Next-Generation Metabolic Screening (NGMS) were performed.</p><p><strong>Results: </strong>Moderate intellectual disability along with obsessive and aggressive behaviour in the context of autism spectrum disorders was established as well as symptoms from the catatonic spectrum. With WES, a novel variant in the <i>TMHLE</i> gene was identified and using NGMS, increased concentration of trimethyllysine and decreased concentration of γ-butyrobetaine were found resulting in a significantly decreased BB/TML ratio, confirming the pathogenicity of this variant.</p><p><strong>Conclusion: </strong>X-linked autism type 6 is characterized by moderate intellectual disability and symptoms from the autism spectrum in the absence of any dysmorphisms. To prevent regressive autistic episodes in young children, it is highly recommended to consider next-generation sequencing techniques as the first step in the differential diagnostic process of autism.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"111-116"},"PeriodicalIF":0.7,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extensive Inactive Neurocysticercosis: A Case Report in Mbeya, Southern Highlands of Tanzania.","authors":"Charles Elias Makasi, Bernard James Ngowi, Dominik Stelzle, Andrew Martin Kilale, Michael Johnson Mahande, Tamara Margarete Welte, Andrea Sylvia Winkler, Blandina Theophil Mmbaga","doi":"10.2147/IMCRJ.S488096","DOIUrl":"10.2147/IMCRJ.S488096","url":null,"abstract":"<p><strong>Background: </strong>Neurocysticercosis (NCC) and Acquired Human Immunodeficiency Syndrome (AIDS) are both highly prevalent in Africa. Clinical presentation of NCC ranges from asymptomatic to manifestations, including epileptic seizures, severe progressive headache, and focal neurological deficits. It is influenced by the number, size, location, and stage of the cysts, as well as the parasite's potential to cause inflammation and the immunological response of the host. So far, little is known about how Human Immunodeficiency Virus (HIV) co-infection modifies clinical NCC presentation. We report the case of a person living with HIV presenting with extensive calcified NCC on neuroimaging without any associated signs/ symptoms.</p><p><strong>Purpose: </strong>To contribute to the medical literature and enhance understanding of the disease's manifestation and progression by providing a thorough documentation of a specific case of extensive inactive neurocysticercosis.</p><p><strong>Case presentation: </strong>A 47-year-old male African patient was recruited in the CYSTINET Africa study at Chunya District Hospital, Mbeya. He was an artisan and has been living with HIV since 2012, and he has been compliant with antiretroviral treatment, hence with undetectable viral load during 2018, 2020, and 2021. <i>Taenia solium</i> serology was done by LDBIO Cysticercosis IgG Western Blot test, which tested positive for antibodies, but the apDia Cysticercosis Antigen (Ag) ELISA antigen test was negative. His computed tomography (CT) scan of the brain showed approximately 138 calcified neurocysticercosis typical lesions, 108 being located in the parenchyma, 15 in the extra parenchyma, and 15 in the subarachnoid space, consistent with a diagnosis of extensive calcified NCC. He reported no history of headaches or epileptic seizures. Neurological examination did not reveal any deficit.</p><p><strong>Conclusion: </strong>Intensively, patients with a large number of neurocysticercosis lesions may be completely asymptomatic throughout the disease. In our patient,the HIV co-infection might have contributed to the high lesion load and/or to less severe clinical signs/symptoms due to modulation of the immune system.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"117-124"},"PeriodicalIF":0.7,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748752/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143004649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coexistence of Anti-GAD and Anti-GABAAR Antibodies in an Autoimmune Encephalitis Patient: A Case Report.","authors":"Xiaoyan Lu, Hangfei Wu, Yuhao Tan, Xiaowei Mao","doi":"10.2147/IMCRJ.S488194","DOIUrl":"10.2147/IMCRJ.S488194","url":null,"abstract":"<p><strong>Background: </strong>Coexistence of autoimmune encephalitis (AE) with multiple autoantibodies is of particular concern because overlying antibodies may cause variation of clinical manifestations. Coexistence of anti-glutamic acid decarboxylase (GAD) and anti-Gamma-aminobutyric acid-α-receptor (GABAAR) antibodies in AE was rare.</p><p><strong>Case presentation: </strong>A 44-year-old female patient presented to our hospital due to cognitive decline for 4 years, seizures, slowed speech and depression for 2 months. Based on her clinical manifestations and laboratory assessment results (positive anti-GAD and anti-GABAAR antibodies), she was diagnosed as AE with coexisting anti-GAD and anti-GABAAR antibodies. After treatment with intravenous methylprednisolone (at dose of 1000mg/d, 500mg/d, 250mg/d, 120mg/d, 80mg/d for 3 days respectively) and intravenous immunoglobulin (400 mg/kg/d for 5 days), her symptoms gradually improved with exception for the slowed speech. Oral prednisone acetate was continued after discharge, her symptoms of slowed speech improved at 6-month follow-up.</p><p><strong>Conclusion: </strong>We report a case of AE co-existing with anti-GAD and anti-GABAAR antibodies, which has different characteristics from previous cases. Coexistence of neural auto-antibodies should be considered when patients suspected with autoimmune encephalitis.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"105-109"},"PeriodicalIF":0.7,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748031/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}