International Medical Case Reports Journal最新文献_第6页

Sickle Cell Disease With Ulcerative Colitis in An Ethiopian Child 埃塞俄比亚儿童镰状细胞病合并溃疡性结肠炎

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International Medical Case Reports Journal Pub Date : 2024-05-01 DOI: 10.2147/imcrj.s453861

A. Tamire, Tenagne Million

引用次数: 0

Insights into Ocular Emergencies: case Series on Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) Secondary to Acute Angle Closure Glaucoma 眼科急症透视：急性闭角型青光眼继发的非动脉炎性前缺血性视神经病变 (NAION) 病例系列

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International Medical Case Reports Journal Pub Date : 2024-05-01 DOI: 10.2147/IMCRJ.S458142

Alia Arianti, Emma Rusmayani, Viona Viona

{"title":"Insights into Ocular Emergencies: case Series on Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) Secondary to Acute Angle Closure Glaucoma","authors":"Alia Arianti, Emma Rusmayani, Viona Viona","doi":"10.2147/IMCRJ.S458142","DOIUrl":"https://doi.org/10.2147/IMCRJ.S458142","url":null,"abstract":"Abstract This case series aims to report the manifestation of acute secondary optic neuropathy attributed to optic nerve injury associated with a singular episode of markedly elevated intraocular pressure (IOP) during an acute glaucoma attack. The correlation between acute primary angle-closure (APAC) and non-arteritic anterior ischemic optic neuropathy (NAION) remains uncertain within the context of current knowledge. Definitive conclusions regarding the causal relationship between APAC and NAION or their mutual influence cannot be established based on the current evidence. The association between these conditions is recognized as a potential link, and comprehensive research is imperative to elucidate their interrelationship thoroughly. This case series emphasizes the importance of promptly addressing acute optic nerve injury and neuropathy associated with elevated intraocular pressure (IOP) in patients with crowded disc anatomical risk factors. It underscores the need for proactive interventions to prevent irreversible damage, highlighting the infrequent yet vision-compromising occurrence of non-arteritic anterior ischemic optic neuropathy (NAION) in acute primary angle-closure (APAC).","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141144584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Giant Clinically Non-Functioning Pituitary Adenoma Presenting as New Onset Generalized Tonic‒Clonic Seizures: A Case Report 临床上无功能的巨大垂体腺瘤表现为新发全身强直-阵挛性发作：病例报告

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International Medical Case Reports Journal Pub Date : 2024-05-01 DOI: 10.2147/imcrj.s465564

Pumudu Weerasekara, Nadeeka Chandraratne, Sunil Perera

引用次数: 0

Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-Associated Optic Neuritis - A Case Report and Literature Review. 髓鞘寡突胶质细胞蛋白（MOG）抗体相关性视神经炎--病例报告和文献综述。

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International Medical Case Reports Journal Pub Date : 2024-04-30 eCollection Date: 2024-01-01 DOI: 10.2147/IMCRJ.S459799

Barbara Nowacka, Wojciech Lubiński, Beata Kaźmierczak

{"title":"Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-Associated Optic Neuritis - A Case Report and Literature Review.","authors":"Barbara Nowacka, Wojciech Lubiński, Beata Kaźmierczak","doi":"10.2147/IMCRJ.S459799","DOIUrl":"https://doi.org/10.2147/IMCRJ.S459799","url":null,"abstract":"Background: Myelin oligodendrocyte glycoprotein (MOG)-IgG-associated optic neuritis (ON) is a new subset of demyelinating optic neuropathy.Case report: This study presents a case of a 49-year-old woman with MOG-IgG-positive ON, who reported to the ophthalmic emergency room with decreased visual acuity, retrobulbar pain and red color desaturation in her left eye. Abnormalities in the ophthalmological examination were: decreased Snellen's distance best-corrected visual acuity (DBCVA) to 0.04 in her left eye, slightly elevated optic nerve disc in the left eye confirmed by increased peripapillary retinal nerve fiber layer (RNFL) thickness in SD-OCT, abnormalities in pattern visual evoked potentials in both eyes. The preliminary diagnosis was demyelinating optic neuritis left for observation. However, two weeks after the first symptoms, treatment with intravenous methylprednisolone was initiated due to a decrease in DBCVA to no light perception. Intravenous steroids were followed by oral prednisone and later also by mycophenolate mofetil. The patient experienced slow but gradual improvement. One year after the occurrence of the initial symptoms, DBCVA was 0.5 in the left eye, however partial atrophy of the optic nerve developed, confirmed by macular ganglion cell layer (GCL) thickness and RNFL atrophy in SD-OCT, while visual pathway function improved.Conclusion: All atypical cases of ON should be primarily considered for cell-based assays. MOG-IgG-positive ON usually responds well to steroid drugs and delaying immunosuppressive treatment may cause irreversible damage to the optic nerve.","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11069371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140851323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outcomes of Proximal Spleno-Renal Shunt Operations for Idiopathic Portal Hypertension in Tertiary Hospital in the Sub-Sahara 撒哈拉沙漠以南地区三级医院对特发性门脉高压症进行近端脾肾分流手术的结果

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International Medical Case Reports Journal Pub Date : 2024-04-01 DOI: 10.2147/imcrj.s453341

M. Okello, S. Srikant, Dave Darshit, P. Ocama

{"title":"Outcomes of Proximal Spleno-Renal Shunt Operations for Idiopathic Portal Hypertension in Tertiary Hospital in the Sub-Sahara","authors":"M. Okello, S. Srikant, Dave Darshit, P. Ocama","doi":"10.2147/imcrj.s453341","DOIUrl":"https://doi.org/10.2147/imcrj.s453341","url":null,"abstract":"Purpose: Idiopathic portal hypertension (IPH) also known as non-cirrhotic portal hypertension is an entity of hepatic conditions including disorders of blood vessels that leads to portal hypertension (PHT). Current management of PHT includes medical or endoscopic therapy. A proximal spleno-renal shunt (PSRS) operation has been shown to improve the outcomes of patients with IPH with upper gastrointestinal bleeding refractory to medical and endoscopic therapy in high income countries but the same has not been well described in our resource limited setting. Patients and methods: This study consecutively included patients who were diagnosed with IPH on pre-operative imaging and underwent PSRS surgery. Data on four patients across the time period of 3 years was obtained with a male to female ratio of 1:1 and age range of 7 to 34 years. Results: All patients in this study had features of upper gastrointestinal bleeding and, after an endoscopy they were all diagnosed with grade IV esophageal varices. Symptom duration prior to admission varied between 3 months to 8 years. All these patients had multiple episodes of rebleeding varices with recurrent admissions and were managed conservatively by multiple blood transfusions and propranolol tablets, pre-operatively. Only one patient had previous variceal band ligation done though he developed rebleeding. All four patients underwent both PSRS surgery and splenectomy and were intra-operatively verified to have a normal smooth liver and thus IPH was the cause of the esophageal varices. After an average follow-up period of 26.5 months, we found that all patients were alive with early symptomatic relief, no recurrent bleeding and no long-term complications. Conclusion: Good outcomes were achieved in terms of symptom resolution, endoscopic variceal resolution at follow-up endoscopy, length of stay ranging from 8 to 15 days and all four patients were alive at the time of follow-up, that ranged from 14 to 46 months.","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140782458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unusual Case of Right-Side Infective Endocarditis in a 40-Year-Old Woman with Postpartum Endometritis: A Case Report 40 岁妇女产后子宫内膜炎并发右侧感染性心内膜炎的罕见病例：病例报告

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International Medical Case Reports Journal Pub Date : 2024-04-01 DOI: 10.2147/IMCRJ.S457389

Sura Markos, Surafel Firdawoke, Eshetu Gagamo, Mintesnot Workeneh

引用次数: 0

Complete Congenital Absence of the Left Pericardium in Elderly Patient: A Case Report 老年患者左心包完全先天缺失：病例报告

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International Medical Case Reports Journal Pub Date : 2024-04-01 DOI: 10.2147/IMCRJ.S454910

Sintayehu Mekonnen, Hawi Farris, Daniel Azmeraw

引用次数: 0

Kaposi’s Sarcoma with Primary Lymph Node Involvement in a Retroviral Infected (RVI) Patient 一名逆转录病毒感染 (RVI) 患者原发性淋巴结受累的卡波西肉瘤

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International Medical Case Reports Journal Pub Date : 2024-04-01 DOI: 10.2147/IMCRJ.S458320

Bizunesh Dires Fenta, Alazar Berhe Aregawi, Teketel Geremew, Berhanu Kelemework Fenta

{"title":"Kaposi’s Sarcoma with Primary Lymph Node Involvement in a Retroviral Infected (RVI) Patient","authors":"Bizunesh Dires Fenta, Alazar Berhe Aregawi, Teketel Geremew, Berhanu Kelemework Fenta","doi":"10.2147/IMCRJ.S458320","DOIUrl":"https://doi.org/10.2147/IMCRJ.S458320","url":null,"abstract":"Abstract One kind of angioproliferative disorder is Kaposi’s sarcoma (KS). Growth of spindle-shaped cells, edema, inflammation, and neoangiogenesis are its defining features. Because it lacks the typical indicators of malignancy, it is classified as an intermediate neoplasm. People who are immunocompromised, receiving organ transplants, or receiving antiretroviral therapy are linked to KS. Although lymph node involvement by KS is extremely uncommon, when it does occur, it usually manifests as either the epidemic form in (Human Immuno-deficiency) HIV-positive patients or the endemic form in Africans. There are four primary clinical manifestations of KS that have been documented: endemic, epidemic, iatrogenic, and classic. The diagnosis of KS is made by history, physical examination, and tissue biopsy. When treating localized disease, highly active antiretroviral therapy (HAART) may be sufficient to either improve or completely eradicate the illness. Nonetheless, chemotherapy and HAART would be necessary in the case of widespread illness. Here, we present the case of a 28-year-old female patient who is HIV positive and has a viral load that is not detected. She presented with generalized lymphadenopathy of 8 months duration. She had no cutaneous manifestations. The lymphadenopathy involved the tonsils, axilla, inguinal, and an unusual site, intraparotid on both sides. After a pathologic examination of the lymph nodes, she was found to have epidemic-type KS and was treated with HAART and chemotherapy. In our nation, we are not aware of any published case reports pertaining to a case like this. The purpose of this case report is to raise physicians’ awareness of this uncommon ailment and to encourage them to suspect KS when HIV patients exhibit generalized lymphadenopathy. The early initiation of systemic treatment is lifesaving for these patients.","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140770349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lethal Immune Myocarditis and Myasthenia Gravis Due to Anti-PD-1 Treatment for a Bladder Cancer Patient: A Case Report and Possible Treatment Inspiration 一名膀胱癌患者因接受抗PD-1治疗而引发致命的免疫性心肌炎和重症肌无力：病例报告和可能的治疗启示

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International Medical Case Reports Journal Pub Date : 2024-04-01 DOI: 10.2147/IMCRJ.S449525

Pan Gao, Xinyu Li, Ziqiu He, Hongbo Zhang, Zhi Zhang, Zonglai Liu

{"title":"Lethal Immune Myocarditis and Myasthenia Gravis Due to Anti-PD-1 Treatment for a Bladder Cancer Patient: A Case Report and Possible Treatment Inspiration","authors":"Pan Gao, Xinyu Li, Ziqiu He, Hongbo Zhang, Zhi Zhang, Zonglai Liu","doi":"10.2147/IMCRJ.S449525","DOIUrl":"https://doi.org/10.2147/IMCRJ.S449525","url":null,"abstract":"Abstract Immune checkpoint inhibitors (ICI) have become a new hope for many patients with advanced cancer by blocking tumor immune escape. Bladder cancer is a common malignant tumor of the urinary tract epithelium that often relapses and metastasizes after surgery, chemotherapy, and radiotherapy. Immunotherapy has dramatically improved patient survival rates and clinical benefits as a new, potentially effective therapy. However, avoidance of various immune-related adverse events (irAEs) remains an implausible idea. ICI-induced myocarditis is different from viral myocarditis, and mortality is still high with the current treatment. We report the case of an 82-year-old female patient with ICI-induced fulminant myocarditis and myasthenia gravis. Although she actively accepted the current mainstream treatment for immune-related myocarditis and myasthenia, she died of heart and respiratory failure. Analyzing and reporting the patient’s disease development process and the changes in related indicators may help peers gain a deeper understanding of immune-related adverse events and reduce the mortality of immune-related myocarditis.","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140789580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pollicization of index Fingers For Bilateral Hypoplastic Thumbs of Twin Babies: Case Series At Cure Children’s Hospital of Ethiopia 食指接骨术治疗双侧拇指发育不良的双胞胎婴儿：埃塞俄比亚治疗儿童医院病例系列

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International Medical Case Reports Journal Pub Date : 2024-04-01 DOI: 10.2147/IMCRJ.S454360

Tuji Mohammed, T. Jimma, Tewodros T. Zerfu, Mesfin Kassaahun

引用次数: 0