脑出血:严重子痫前期的致命并发症——资源有限的罕见病例报告。

IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL
International Medical Case Reports Journal Pub Date : 2025-05-11 eCollection Date: 2025-01-01 DOI:10.2147/IMCRJ.S516956
Ibrahim Abdullahi Mohamed, Abdullahi Abdirahman Omar, Mulki Mukhtar Hassan, Mohamed Abdulahi Hassan, Zakaria Mohamed Adan, Zubeir Abdulkadir Mohamed
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引用次数: 0

摘要

背景:脑出血(ICH)是子痫前期罕见但严重的并发症,是孕产妇发病率和死亡率的重要因素,特别是在资源有限的地区。潜在的机制包括内皮功能障碍、脑自动调节功能衰竭和血脑屏障的破坏。本病例报告旨在强调严重先兆子痫合并ICH的独特表现,强调在资源有限的环境中遇到的障碍,并讨论长期影响和预后。病例介绍:一名35岁的多胎妇女,产后两天出现精神状态改变、失语和右侧偏瘫。她的妊娠伴有严重的先兆子痫和宫内胎儿死亡。计算机断层扫描(CT)显示左侧基底神经节出血延伸至脑室。她接受了保守治疗,包括抗高血压药物、硫酸镁预防癫痫发作和抗水肿治疗。尽管诊断资源有限,但实验室评估排除了凝血病和血管异常。经过20天的多学科治疗,患者的神经功能得到了明显的恢复。随访4周后显示功能完全恢复,并通过重复CT确诊。结论:该病例独特地强调了及时的多学科护理和强有力的产前监测对于减轻脑出血与先兆子痫相关的严重并发症的重要性。即使在资源受限的环境中,患者的完全恢复也突出了保守治疗成功的潜力。未来的临床实践和研究应侧重于改善产前保健的可及性、患者教育和制定具体情况的管理指南,以减少类似情况下的孕产妇发病率和死亡率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Intracerebral Hemorrhage: A Fatal Complication of Severe Preeclampsia-A Rare Case Report in a Resource-Limited Setting.

Background: Intracerebral hemorrhage (ICH) is a rare but severe complication of preeclampsia, significantly contributing to maternal morbidity and mortality, particularly in resource-limited settings. The underlying mechanisms include endothelial dysfunction, cerebral autoregulation failure, and breakdown of the blood-brain barrier. This case report aims to highlight a unique presentation of severe preeclampsia complicated by ICH, emphasizing barriers encountered in resource-limited settings and discussing long-term implications and prognosis.

Case presentation: A 35-year-old multiparous woman presented two days postpartum with altered mental status, aphasia, and right-sided hemiparesis. Her pregnancy was complicated by severe preeclampsia and intrauterine fetal death. Computed tomography (CT) revealed a left basal ganglia hemorrhage extending into the ventricles. She received conservative management including antihypertensive medications, magnesium sulfate for seizure prophylaxis, and anti-edema therapy. Despite limited diagnostic resources, laboratory evaluations ruled out coagulopathies and vascular anomalies. After 20 days of multidisciplinary care, significant neurological recovery was achieved. Follow-up after four weeks demonstrated complete functional recovery, with resolution confirmed by repeat CT.

Conclusion: This case uniquely underscores the critical importance of timely multidisciplinary care and robust antenatal monitoring in mitigating severe complications such as ICH associated with preeclampsia. The patient's full recovery highlights the potential for successful conservative management even in resource-constrained environments. Future clinical practice and research should focus on improving antenatal care accessibility, patient education, and developing context-specific management guidelines to reduce maternal morbidity and mortality in similar settings.

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来源期刊
International Medical Case Reports Journal
International Medical Case Reports Journal MEDICINE, GENERAL & INTERNAL-
CiteScore
1.40
自引率
0.00%
发文量
135
审稿时长
16 weeks
期刊介绍: International Medical Case Reports Journal is an international, peer-reviewed, open access, online journal publishing original case reports from all medical specialties. Submissions should not normally exceed 3,000 words or 4 published pages including figures, diagrams and references. As of 1st April 2019, the International Medical Case Reports Journal will no longer consider meta-analyses for publication.
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