Ibrahim Abdullahi Mohamed, Abdullahi Abdirahman Omar, Mulki Mukhtar Hassan, Mohamed Abdulahi Hassan, Zakaria Mohamed Adan, Zubeir Abdulkadir Mohamed
{"title":"脑出血:严重子痫前期的致命并发症——资源有限的罕见病例报告。","authors":"Ibrahim Abdullahi Mohamed, Abdullahi Abdirahman Omar, Mulki Mukhtar Hassan, Mohamed Abdulahi Hassan, Zakaria Mohamed Adan, Zubeir Abdulkadir Mohamed","doi":"10.2147/IMCRJ.S516956","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Intracerebral hemorrhage (ICH) is a rare but severe complication of preeclampsia, significantly contributing to maternal morbidity and mortality, particularly in resource-limited settings. The underlying mechanisms include endothelial dysfunction, cerebral autoregulation failure, and breakdown of the blood-brain barrier. This case report aims to highlight a unique presentation of severe preeclampsia complicated by ICH, emphasizing barriers encountered in resource-limited settings and discussing long-term implications and prognosis.</p><p><strong>Case presentation: </strong>A 35-year-old multiparous woman presented two days postpartum with altered mental status, aphasia, and right-sided hemiparesis. Her pregnancy was complicated by severe preeclampsia and intrauterine fetal death. Computed tomography (CT) revealed a left basal ganglia hemorrhage extending into the ventricles. She received conservative management including antihypertensive medications, magnesium sulfate for seizure prophylaxis, and anti-edema therapy. Despite limited diagnostic resources, laboratory evaluations ruled out coagulopathies and vascular anomalies. After 20 days of multidisciplinary care, significant neurological recovery was achieved. Follow-up after four weeks demonstrated complete functional recovery, with resolution confirmed by repeat CT.</p><p><strong>Conclusion: </strong>This case uniquely underscores the critical importance of timely multidisciplinary care and robust antenatal monitoring in mitigating severe complications such as ICH associated with preeclampsia. The patient's full recovery highlights the potential for successful conservative management even in resource-constrained environments. Future clinical practice and research should focus on improving antenatal care accessibility, patient education, and developing context-specific management guidelines to reduce maternal morbidity and mortality in similar settings.</p>","PeriodicalId":14337,"journal":{"name":"International Medical Case Reports Journal","volume":"18 ","pages":"545-551"},"PeriodicalIF":0.7000,"publicationDate":"2025-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12080481/pdf/","citationCount":"0","resultStr":"{\"title\":\"Intracerebral Hemorrhage: A Fatal Complication of Severe Preeclampsia-A Rare Case Report in a Resource-Limited Setting.\",\"authors\":\"Ibrahim Abdullahi Mohamed, Abdullahi Abdirahman Omar, Mulki Mukhtar Hassan, Mohamed Abdulahi Hassan, Zakaria Mohamed Adan, Zubeir Abdulkadir Mohamed\",\"doi\":\"10.2147/IMCRJ.S516956\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Intracerebral hemorrhage (ICH) is a rare but severe complication of preeclampsia, significantly contributing to maternal morbidity and mortality, particularly in resource-limited settings. The underlying mechanisms include endothelial dysfunction, cerebral autoregulation failure, and breakdown of the blood-brain barrier. This case report aims to highlight a unique presentation of severe preeclampsia complicated by ICH, emphasizing barriers encountered in resource-limited settings and discussing long-term implications and prognosis.</p><p><strong>Case presentation: </strong>A 35-year-old multiparous woman presented two days postpartum with altered mental status, aphasia, and right-sided hemiparesis. Her pregnancy was complicated by severe preeclampsia and intrauterine fetal death. Computed tomography (CT) revealed a left basal ganglia hemorrhage extending into the ventricles. She received conservative management including antihypertensive medications, magnesium sulfate for seizure prophylaxis, and anti-edema therapy. Despite limited diagnostic resources, laboratory evaluations ruled out coagulopathies and vascular anomalies. After 20 days of multidisciplinary care, significant neurological recovery was achieved. Follow-up after four weeks demonstrated complete functional recovery, with resolution confirmed by repeat CT.</p><p><strong>Conclusion: </strong>This case uniquely underscores the critical importance of timely multidisciplinary care and robust antenatal monitoring in mitigating severe complications such as ICH associated with preeclampsia. The patient's full recovery highlights the potential for successful conservative management even in resource-constrained environments. Future clinical practice and research should focus on improving antenatal care accessibility, patient education, and developing context-specific management guidelines to reduce maternal morbidity and mortality in similar settings.</p>\",\"PeriodicalId\":14337,\"journal\":{\"name\":\"International Medical Case Reports Journal\",\"volume\":\"18 \",\"pages\":\"545-551\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2025-05-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12080481/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Medical Case Reports Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2147/IMCRJ.S516956\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Medical Case Reports Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2147/IMCRJ.S516956","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Intracerebral Hemorrhage: A Fatal Complication of Severe Preeclampsia-A Rare Case Report in a Resource-Limited Setting.
Background: Intracerebral hemorrhage (ICH) is a rare but severe complication of preeclampsia, significantly contributing to maternal morbidity and mortality, particularly in resource-limited settings. The underlying mechanisms include endothelial dysfunction, cerebral autoregulation failure, and breakdown of the blood-brain barrier. This case report aims to highlight a unique presentation of severe preeclampsia complicated by ICH, emphasizing barriers encountered in resource-limited settings and discussing long-term implications and prognosis.
Case presentation: A 35-year-old multiparous woman presented two days postpartum with altered mental status, aphasia, and right-sided hemiparesis. Her pregnancy was complicated by severe preeclampsia and intrauterine fetal death. Computed tomography (CT) revealed a left basal ganglia hemorrhage extending into the ventricles. She received conservative management including antihypertensive medications, magnesium sulfate for seizure prophylaxis, and anti-edema therapy. Despite limited diagnostic resources, laboratory evaluations ruled out coagulopathies and vascular anomalies. After 20 days of multidisciplinary care, significant neurological recovery was achieved. Follow-up after four weeks demonstrated complete functional recovery, with resolution confirmed by repeat CT.
Conclusion: This case uniquely underscores the critical importance of timely multidisciplinary care and robust antenatal monitoring in mitigating severe complications such as ICH associated with preeclampsia. The patient's full recovery highlights the potential for successful conservative management even in resource-constrained environments. Future clinical practice and research should focus on improving antenatal care accessibility, patient education, and developing context-specific management guidelines to reduce maternal morbidity and mortality in similar settings.
期刊介绍:
International Medical Case Reports Journal is an international, peer-reviewed, open access, online journal publishing original case reports from all medical specialties. Submissions should not normally exceed 3,000 words or 4 published pages including figures, diagrams and references. As of 1st April 2019, the International Medical Case Reports Journal will no longer consider meta-analyses for publication.