International Archives of Otorhinolaryngology最新文献_第6页

An Analysis Between Body Composition and Vertigo Post-Coronavirus Disease 2019 Patients. 2019冠状病毒感染后患者体成分与眩晕的关系分析

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International Archives of Otorhinolaryngology Pub Date : 2025-04-15 eCollection Date: 2025-04-01 DOI: 10.1055/s-0044-1791729

Luciana Lozza de Moraes Marchiori, Glória de Moraes Marchiori, Licia Sayuri Tanaka Okamura, Daiane Soares de Almeida Ciquinato, Braulio Henrique Magnani Branco

{"title":"An Analysis Between Body Composition and Vertigo Post-Coronavirus Disease 2019 Patients.","authors":"Luciana Lozza de Moraes Marchiori, Glória de Moraes Marchiori, Licia Sayuri Tanaka Okamura, Daiane Soares de Almeida Ciquinato, Braulio Henrique Magnani Branco","doi":"10.1055/s-0044-1791729","DOIUrl":"https://doi.org/10.1055/s-0044-1791729","url":null,"abstract":"Introduction An association between the sensation of vertigo, and body composition has not been investigated in post-coronavirus disease 2019 (COVID-19) patients. Objective To evaluate the probable association between the sensation of vertigo and body composition-as amount of fat, bone, and muscle-in post-COVID-19 patients. Methods Cross-sectional study with a sample of post-COVID-19 patients who responded to the visual analog scale (VAS) and the Dizziness Handicap Inventory (DHI). Clinical assessment and electrical bioimpedance were used to determine body composition. Results There were 105 participants evaluated, 61% (n = 64) of whom were male, aged 49.5 ± 11.7 years, with an average height of 165.6 ± 19.9 cm, body weight of 87.6 ± 20 kg, and body mass index (BMI) of 31.1 ± 5.4 kg/m. The prevalence of self-reported vertigo was 51.4% (n = 54); of these, 11.4% (n = 12) related vertigo before the diagnosis of COVID-19, and 40% (n = 42) related vertigo during or after COVID-19. Furthermore, 37.2% (n = 39) of the sample reported that vertigo persisted after medical discharge. In the comparative analysis, the data showed a significant difference between the groups with and without vertigo for height ( p = 0.001), body mass ( p = 0.006), body water ( p = 0.001), lean mass ( p = 0.002), fat-free mass ( p = 0.001), and musculoskeletal mass ( p = 0.001). Conclusion There was a significant association between body composition and the complaint of vertigo in post-COVID-19 patients, suggesting that these aspects should be considered when assessing and can contribute to the construction of knowledge about long COVID.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-8"},"PeriodicalIF":1.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of Preoperative Thyroid-Stimulating Hormone Levels in the Prediction of Thyroid Hormone Replacement after Hemithyroidectomy. 术前促甲状腺激素水平在预测甲状腺切除术后甲状腺激素替代中的作用。

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International Archives of Otorhinolaryngology Pub Date : 2025-04-15 eCollection Date: 2025-04-01 DOI: 10.1055/s-0045-1801852

Ramona Paula Fernandes Reckziegel, Lenara Golbert, Erika Laurini de Souza Meyer

{"title":"Role of Preoperative Thyroid-Stimulating Hormone Levels in the Prediction of Thyroid Hormone Replacement after Hemithyroidectomy.","authors":"Ramona Paula Fernandes Reckziegel, Lenara Golbert, Erika Laurini de Souza Meyer","doi":"10.1055/s-0045-1801852","DOIUrl":"https://doi.org/10.1055/s-0045-1801852","url":null,"abstract":"Introduction Hemithyroidectomy is performed for the treatment of symptomatic unilateral benign nodules, cytologically indeterminate nodules, and some cases of well-differentiated thyroid cancer. Objective To evaluate the frequency of postlobectomy thyroid hormone replacement (THR), and to analyze the clinical-pathological factors predicting L-thyroxine (T4) use in patients undergoing hemithyroidectomy. Methods We conducted an observational, retrospective study in which clinical, biochemical, and anatomopathological parameters were analyzed and correlated with the need for THR after thyroid lobectomy. Results The frequency of postoperative THR was 63%. The preoperative thyroid-stimulating hormone (TSH) level was an important predictor of postoperative THR. When stratifying preoperative TSH levels, the frequencies of T4 replacement in each TSH quartile varied, being more frequent with increasing presurgical TSH levels ( p = 0.029). The preoperative cutoff that maximized sensitivity and specificity for the development of hypothyroidism was 1.21 μIU/mL. Conclusion Our results demonstrated a significant frequency of postlobectomy THR. Higher preoperative TSH is a strong risk factor for postsurgical hypothyroidism, and even lower preoperative levels within the normal references do not exclude the risk of thyroid hormone use after thyroid lobectomy.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-6"},"PeriodicalIF":1.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Regenerated Oxidized Cellulose as a Sealant and Adhesive in Endoscopic Endonasal Skull Base Reconstruction. 再生氧化纤维素在鼻内窥镜颅底重建中的应用。

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International Archives of Otorhinolaryngology Pub Date : 2025-04-15 eCollection Date: 2025-04-01 DOI: 10.1055/s-0044-1788599

Ashwin Gajendran Vedhapoodi, Aravind Sabesan, Benazir Ferozkhan, Saravana Selvan Velmurugan, Venkatesan Rajarajan, Baskar Arukavur Radhakrishnan, Kanagaraman Prabhuraman, Bhuvaneswari Natarajan

{"title":"Regenerated Oxidized Cellulose as a Sealant and Adhesive in Endoscopic Endonasal Skull Base Reconstruction.","authors":"Ashwin Gajendran Vedhapoodi, Aravind Sabesan, Benazir Ferozkhan, Saravana Selvan Velmurugan, Venkatesan Rajarajan, Baskar Arukavur Radhakrishnan, Kanagaraman Prabhuraman, Bhuvaneswari Natarajan","doi":"10.1055/s-0044-1788599","DOIUrl":"https://doi.org/10.1055/s-0044-1788599","url":null,"abstract":"Introduction An ideal and long-lasting adhesive and sealant is essential during endoscopic endonasal skull-base surgery to hold the reconstruction intact and prevent cerebrospinal fluid (CSF) permeation until complete healing occurs. Fibrin glue is the most common material used. Regenerated oxidized cellulose (ROC) has not been mentioned in the literature as sealant and adhesive, and, hence, we intended to study this role. Objective To evaluate the role of ROC as tissue sealant and adhesive in the reconstruction of skull-base defects in endoscopic endonasal skull-base surgery. Methods We retrospectively analyzed the medical records of patients who underwent endoscopic endonasal skull-base surgery with skull-base defect and intraoperative CSF leak, for which reconstruction was performed using fibrin glue or ROC, or both, as a sealant and adhesive. The type of sealant and adhesive used and postoperative CSF leak rates with different agents used were analyzed. Results A total of 64 patients were investigated. Fibrin glue alone was used initially in 6 patients, of which 4 (66.6%) experienced postoperative CSF leak. Both fibrin glue and ROC were used in 26 patients, among which 2 (7.6%) exhibited postoperative CSF leak. Regenerated oxidized cellulose alone was used in 24 patients, wherein 2 (8.3%) presented with postoperative CSF leak. Fibrin glue alone was once again used later in the learning curve in 8 patients, of which 2 (25%) experienced postoperative CSF leak ( p = 0.002). Conclusion Fibrin glue provides intraoperative watertight seal. Regenerated oxidized cellulose has better intraoperative and long-term sealant and adhesive action in endoscopic endonasal skull-base reconstruction.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-10"},"PeriodicalIF":1.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020577/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143994173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Blood IgE and Eosinophils are not Reliable Predictors of Nasal Tissue Eosinophils in Chronic Rhinosinusitis with Nasal Polyposis. 慢性鼻窦炎伴鼻息肉病患者血IgE和嗜酸性粒细胞不能可靠地预测鼻组织嗜酸性粒细胞。

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International Archives of Otorhinolaryngology Pub Date : 2025-04-15 eCollection Date: 2025-04-01 DOI: 10.1055/s-0044-1801316

Judy Fan, William Daniels, Athenea Pascual, Changwan Ryu, Masih Sarafan, Miguel Soares Tepedino, Richard Louis Voegels, Marco Aurélio Fornazieri, Don Sin, Rogério Pezato, Andrew Thamboo

{"title":"Blood IgE and Eosinophils are not Reliable Predictors of Nasal Tissue Eosinophils in Chronic Rhinosinusitis with Nasal Polyposis.","authors":"Judy Fan, William Daniels, Athenea Pascual, Changwan Ryu, Masih Sarafan, Miguel Soares Tepedino, Richard Louis Voegels, Marco Aurélio Fornazieri, Don Sin, Rogério Pezato, Andrew Thamboo","doi":"10.1055/s-0044-1801316","DOIUrl":"https://doi.org/10.1055/s-0044-1801316","url":null,"abstract":"Introduction Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a chronic inflammatory condition of the paranasal sinuses that is mainly associated with type-2 inflammation. Immunoglobulin E (IgE) and eosinophils in blood and nasal tissue have been suggested as biomarkers for the prognosis and severity of CRSwNP as well as indications for biological treatment. Objective The present study aims to assess the relationships between blood IgE concentration, blood eosinophil count, and nasal polyp eosinophil count in CRSwNP patients. Methods The present study is retrospective. Nasal polyps from CRSwNP patients (n = 73) were fixed and embedded in paraffin for hematoxylin and eosin stain. Blood was collected to measure IgE concentration and eosinophil count. Results Weak correlations were found between blood and tissue eosinophil counts ( p = 0.004, r = 0.367) as well as blood IgE concentration and blood eosinophil count ( p = 0.007, r = 0.372). There was no statistically significant correlation between blood IgE concentration and tissue eosinophil count. When dividing patients based on nasal polyp eosinophil count, blood eosinophil level was higher in the severely eosinophilic group than in the mildly eosinophilic group ( p = 0.002). Conclusion Blood IgE and eosinophils are not reliable biomarkers to predict the inflammatory condition in CRSwNP. Further research is needed on the clinical roles of these biomarkers.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-5"},"PeriodicalIF":1.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Video Clinics for Nasal Bone Injuries in COVID Times - Is it a Valid Tool for Routine Practice? 新冠肺炎时期鼻骨损伤视频诊疗——它是常规诊疗的有效工具吗？

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International Archives of Otorhinolaryngology Pub Date : 2025-04-15 eCollection Date: 2025-04-01 DOI: 10.1055/s-0044-1801313

Ved Narang, Megan McGlone, Nick Calder

{"title":"Video Clinics for Nasal Bone Injuries in COVID Times - Is it a Valid Tool for Routine Practice?","authors":"Ved Narang, Megan McGlone, Nick Calder","doi":"10.1055/s-0044-1801313","DOIUrl":"https://doi.org/10.1055/s-0044-1801313","url":null,"abstract":"Introduction We previously investigated the impact of video clinics on the management of closed nasal bone injuries during the coronavirus disease 2019 (COVID-19) pandemic. The aim of that study was to assess the feasibility of managing patients at their homes or workplaces, with instructions to attend outpatient clinics the next working day if they suspected any deviation or reduced nasal airflow, for further evaluation. Objective To compare the results of our previous research with the traditional, in-person nasal injury clinics, using the same criteria as in our prior investigation. Methods We analyzed 3 months of preexisting data from video clinics and collected 6 months of data from face-to-face clinics. We gathered information on the number of patients, categorized by age and gender, as well as records of missed appointments (DNAs) and the requirement for nasal manipulations. Data analysis was conducted using the Chi-Squared test in SciPy Python 3.0 (open source). Results The statistical analysis revealed no significant differences between the 2 groups concerning the number of patients with closed nasal bone injuries, both under and over 18 years of age ( p -value: 0.961), the rate of missed appointments ( p -value: 0.0734), and the need for fracture reduction ( p -value: 0.0734). Conclusions The findings suggest that video clinics are equally effective in managing suspected nasal bone injuries and should not be restricted to emergency situations. However, it is advisable to adopt a balanced approach considering the additional costs associated with appointments.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-5"},"PeriodicalIF":1.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maxillary Sinus Assessment: A Computed Tomography Analysis and Classification. 上颌窦评估：计算机断层分析和分类。

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International Archives of Otorhinolaryngology Pub Date : 2025-04-15 eCollection Date: 2025-04-01 DOI: 10.1055/s-0044-1791728

Mohammad Waheed El-Anwar, Mohamed Kamel Alawady, Hoda Ismail Abdelhamid, Tamer Oraby, Mohamed Talaat Albasiouny, Ashraf El-Hussiny

{"title":"Maxillary Sinus Assessment: A Computed Tomography Analysis and Classification.","authors":"Mohammad Waheed El-Anwar, Mohamed Kamel Alawady, Hoda Ismail Abdelhamid, Tamer Oraby, Mohamed Talaat Albasiouny, Ashraf El-Hussiny","doi":"10.1055/s-0044-1791728","DOIUrl":"https://doi.org/10.1055/s-0044-1791728","url":null,"abstract":"Introduction The preoperative assessment of the computed tomography (CT) characteristics of the maxillary sinus helps to preserve its anatomical and functional integrity during and after surgery. Objective To use CT scanning to identify maxillary sinus variations and types that were not previously published. Methods The present study was carried out on 110 paranasal CT scans (220 sides). Axial images were obtained with multiplanar scans, to visualize details in coronal and sagittal planes for all subjects. Results Among the 110 CTs (220 sides) of the maxillary sinus's floor, there were 53.2% type 1, 29.1% type 2, 10% type 3, and 7.7% type 4, with significant difference between genders. The most common maxillary sinus floor was type 1. The lateral maxillary sinus wall was found to be type 1 in 32.7%, type 2 in 65%, and type 3 in 2.3%, with a significant difference between genders. The most common lateral wall of the maxillary sinus type was type 2. The orbital floor was found to be type 1 in 0.9%, type 2 in 21.3%, type 3 in 50.5%, and type 4 in 27.3%, without significant difference between genders. Asymmetry was detected between the right and left sides for the maxillary sinus floor of in 22.7%, lateral maxillary wall in 16%, and orbital floor (maxillary roof) in 30%. Conclusion This study aims to increase surgeons' awareness of maxillary sinus variations, creating new classifications for usage and communication in the otorhinolaryngology and endoscopic fields. It could also be helpful for training medical residents.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-6"},"PeriodicalIF":1.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143994169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Frequency of Oral Behaviors as a Risk Factor for Somatosensory Tinnitus. 口腔行为频率是体感耳鸣的危险因素。

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International Archives of Otorhinolaryngology Pub Date : 2025-04-15 eCollection Date: 2025-04-01 DOI: 10.1055/s-0045-1802577

Ana Carolina de Oliveira Garcia D'Amato, Thaís Spisila, Gabriela Schumacher de Camargo, Priscila Brenner Hilgenberg-Sydney

{"title":"Frequency of Oral Behaviors as a Risk Factor for Somatosensory Tinnitus.","authors":"Ana Carolina de Oliveira Garcia D'Amato, Thaís Spisila, Gabriela Schumacher de Camargo, Priscila Brenner Hilgenberg-Sydney","doi":"10.1055/s-0045-1802577","DOIUrl":"https://doi.org/10.1055/s-0045-1802577","url":null,"abstract":"Introduction Somatosensory tinnitus is a type of tinnitus that can be modified by somatosensory stimuli from the cervical spine and temporomandibular area. Temporomandibular disorders and oral behaviors are associated with a higher prevalence of somatosensory tinnitus, and this association is described in the literature as part of the diagnosis of this condition. Objective To verify the association between somatosensory tinnitus and oral behaviors. Methods Patients were recruited from an Orofacial Pain outpatient clinic and from Head and Neck Unit. All participants underwent anamnesis, physical examination and completed the Oral Behaviors Checklist questionnaire. Forty-six patients were divided into 2 groups, each consisting of 23 patients: somatosensory tinnitus group (STG) and a comparison group (CG), with subjective tinnitus. Data were gathered and analyzed using the Jamovi software (open source) and a significance level of 5% was adopted. Somatosensory tinnitus was associated with dizziness and neck and temporomandibular joint pain. Results There was an association between a higher Oral Behaviors Checklist score and the presence of somatosensory tinnitus. For each point marked on Oral Behaviors Checklist, there was an 8.2% greater chance of having somatosensory tinnitus. Tinnitus modulation through somatic maneuvers and palpation of masticatory and cervical muscles was significantly associated with somatosensory tinnitus. Conclusion Dizziness and neck and temporomandibular joint pain are associated with the presence of somatosensory tinnitus. Probable sleep and awake bruxism are not exclusive behaviors of somatosensory tinnitus patients. However, their frequency may impact its presence.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-5"},"PeriodicalIF":1.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020596/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Otorhinolaryngology Foundation: Three Decades of Excellence in Education, Research, and Scientific Advancement. 耳鼻喉科基金会：卓越的教育、研究和科学进步三十年。

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International Archives of Otorhinolaryngology Pub Date : 2025-02-10 eCollection Date: 2025-01-01 DOI: 10.1055/s-0044-1801808

Ricardo Ferreira Bento, Adilson Marcos Montefusco, Greice Vitória Garcia Ribeiro, Annita Luz Lacerda Lowndes, Adriana de Almeida Fozzati

{"title":"Otorhinolaryngology Foundation: Three Decades of Excellence in Education, Research, and Scientific Advancement.","authors":"Ricardo Ferreira Bento, Adilson Marcos Montefusco, Greice Vitória Garcia Ribeiro, Annita Luz Lacerda Lowndes, Adriana de Almeida Fozzati","doi":"10.1055/s-0044-1801808","DOIUrl":"10.1055/s-0044-1801808","url":null,"abstract":"Introduction The Otorhinolaryngology Foundation (FO), created in 1995, has played an important role in the advancement of otorhinolaryngology in Brazil, through initiatives in education, research, and service provision. Objective To present the trajectory of FO's 30 years in public health and professional training, highlighting its contributions, historical milestones, and future challenges. Brief History Created by the Center for Studies and Advanced Development in Otorhinolaryngology (CEDAO), the FO expanded its activities beyond academic support, becoming a national reference. Among its achievements, the commitment to the continuous improvement of teaching, research, publications, and provision of services to the community stands out. These initiatives include the promotion of courses and conferences that train thousands of professionals, the dissemination of knowledge through scientific publications, the development of innovative technologies, and the carrying out of campaigns and assistance actions aimed at the population. Final Considerations The celebration of FO's 30th anniversary reaffirms its mission of excellence and innovation in the dissemination of knowledge in otorhinolaryngology in Brazil. The continuous commitment to improving its four fundamental pillars ensures quality in education, research, and service to society.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 1","pages":"1-13"},"PeriodicalIF":1.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11810455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Change in Symptoms and Mucosal Findings after Proton Pump Inhibitor in Patients with Laryngopharyngeal Reflux. 咽部反流患者质子泵抑制剂治疗后症状和粘膜表现的变化

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International Archives of Otorhinolaryngology Pub Date : 2025-02-06 eCollection Date: 2025-01-01 DOI: 10.1055/s-0044-1791642

Min Woo Park, Sin Jae Kang, Jee Hye Wee

{"title":"Change in Symptoms and Mucosal Findings after Proton Pump Inhibitor in Patients with Laryngopharyngeal Reflux.","authors":"Min Woo Park, Sin Jae Kang, Jee Hye Wee","doi":"10.1055/s-0044-1791642","DOIUrl":"10.1055/s-0044-1791642","url":null,"abstract":"Introduction Although there are several reports of endoscopic findings of the larynx and esophagus in laryngopharyngeal reflux (LPR) patients, little is known about the correlation between change in symptoms and laryngeal and esophageal mucosal findings after proton pump inhibitor (PPI) treatment. Objective The present study aimed to evaluate the changes in symptoms and mucosal findings of the larynx and esophagus using transnasal esophagoscopy (TNE) after PPI medication and to analyze their relationship in LPR patients. Methods The current prospective study included 36 patients who complained of LPR symptoms. Reflux Symptom Index (RSI), Reflux Finding Score (RFS), and modified Los Angeles classification using TNE were obtained pretreatment and 8 weeks after treatment with PPIs. Results Data from 22 patients who completed all examinations were analyzed. The mean age was 52.8 years, and 4 patients were men. The most common symptom was a globus sensation (54.6%). Both RSI ( p < 0.001) and RFS ( p < 0.001) were significantly improved after 8 weeks with PPI treatment. However, there was no correlation between improvement of RSI and RFS ( p = 0.350). Thirteen patients showed improvement in esophageal findings. However, there was no significant association between improvement of esophageal findings and RSI ( p = 0.350) or RFS ( p = 0.376). Conclusion Although PPI treatment improved LPR symptoms and endoscopic findings, the change in symptoms was not related to endoscopic mucosal findings in the larynx and esophagus.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 1","pages":"1-6"},"PeriodicalIF":1.0,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11802262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Near Point of Convergence in Patients with Vestibular Migraine. 前庭偏头痛患者的近收敛点。

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International Archives of Otorhinolaryngology Pub Date : 2025-02-05 eCollection Date: 2025-01-01 DOI: 10.1055/s-0044-1791643

Francisco Carlos Zuma E Maia, Bernardo Faria Ramos, Roseli Saraiva Moreira Bittar, Renato Valerio Rodrigues Cal, Leonel Almeida Luís, Pedro Luiz Mangabeira Albernaz

{"title":"The Near Point of Convergence in Patients with Vestibular Migraine.","authors":"Francisco Carlos Zuma E Maia, Bernardo Faria Ramos, Roseli Saraiva Moreira Bittar, Renato Valerio Rodrigues Cal, Leonel Almeida Luís, Pedro Luiz Mangabeira Albernaz","doi":"10.1055/s-0044-1791643","DOIUrl":"10.1055/s-0044-1791643","url":null,"abstract":"Introduction Vestibular migraine (VM) is one of the most common vestibular disorders and its diagnosis is based entirely on clinical features. A recent case series suggested a possible link between migraines and convergence insufficiency. Objective To compare the near point of convergence (NPC) in patients with and without VM. Methods We retrospectively reviewed the data of 50 patients with and 50 without VM, comparing the NPC between both groups. The NPC was measured according to the recommendations of the American Academy of Ophthalmology. Differences in the results between groups were compared using the Mann-Whitney test. The association of the NPC with age, gender, and the use of corrective glasses or contact lenses was evaluated by the Student t or Mann-Whitney tests for parametric and nonparametric data, respectively. To determine the diagnostic accuracy and optimal cut-off point, receiver operating characteristic (ROC) curves were created. Results The mean NPC was significantly higher in patients with VM (18.50 ± 5.88 cm) compared to the control group (8.06 ± 1.46 cm; p < 0.001). The area under the curve (AUC) was 0.986 (95% CI: 0.938-0.999; p < 0.0001), suggesting that NPC was able to accurately discriminate between patients with and without VM with a sensitivity of 94% and specificity of 100%. Conclusion Our results suggest that convergence insufficiency is a common sign in patients with VM and may be considered a potential clinical biomarker. However, further studies are needed to confirm this hypothesis.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 1","pages":"1-4"},"PeriodicalIF":1.0,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11798653/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0