International Archives of Otorhinolaryngology最新文献

{"title":"Timing Effect on Transient Evoked Otoacoustic Emission Referral Rates for Newborn Hearing Screening within and after 48 Hours of Birth.","authors":"Chuan Cheepcharoenrat, Amaraporn Rerkasem","doi":"10.1055/s-0045-1802580","DOIUrl":"https://doi.org/10.1055/s-0045-1802580","url":null,"abstract":"<p><strong>Introduction: </strong>Newborn hearing screenings must be completed within 48 hours of birth.</p><p><strong>Objective: </strong>To determine the optimal timing for the first transient evoked otoacoustic emissions (TEOAEs) test by comparing the referral rates of infants tested between different time intervals.</p><p><strong>Methods: </strong>The present study was a retrospective cohort analysis of 2,713 newborns who underwent TEOAE tests between February 2021 and June 2022. The infants were categorized into groups according to the age at which they were tested: 12 to 24 hours, 25 to 36 hours, 37 to 48 hours, and > 48 hours. We compared referral rates across these groups.</p><p><strong>Results: </strong>The overall referral rate for infants tested within 48 hours from birth was 53%, significantly higher than the rate for those tested after 48 hours (46%, <i>p</i>  = 0.001). Notably, the highest referral rates were observed in neonates aged 25 to 36 hours. However, no significant difference in referral rates was found for high-risk infants tested either before or after 48 hours.</p><p><strong>Conclusion: </strong>Transient evoked otoacoustic emissions can be used to screen newborns' hearing within 48 hours, but the high referral rate suggests that Thailand should add automated auditory brainstem response (AABR) to its guidelines for hearing evaluation if newborns leave the hospital before 48 hours.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 3","pages":"1-8"},"PeriodicalIF":1.1,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12307080/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144742044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy, Safety, and Tolerability of Nasal Wash in Patients with Upper Respiratory Tract Diseases.","authors":"Ignazio La Mantia, Giovanna Stilo, Lepanto Lentini, Giorgio Ciprandi","doi":"10.1055/s-0045-1802576","DOIUrl":"https://doi.org/10.1055/s-0045-1802576","url":null,"abstract":"<p><strong>Introduction: </strong>Nasal irrigation is a standard therapeutic option to clean the upper airways to remove abundant secretions and harmful substances. The Nasal Wash (SIIT, Milan, Italy) sinus irrigation system contains saline, bicarbonates, and polyethylene glycol.</p><p><strong>Objective: </strong>The present randomized controlled trial evaluated and compared the Nasal Wash hypertonic solution (NW-HS) with physiological saline (PS) in patients with nasal symptoms common to different upper airway diseases (infectious rhinitis, allergic rhinitis, and acute and chronic rhinosinusitis).</p><p><strong>Methods: </strong>The symptomatic patients were divided into two groups: those receiving NW-HS 1 to 2 times a day for 7 days and those receiving PS 1 to 2 times a day for 7 days. The primary efficacy measures included total nasal symptom score (TNSS) and the score on the verbal numeric rating scale (VNRS), assessed at baseline and during the treatment period.</p><p><strong>Results: </strong>In total, 70 patients participated in the trial: 35 were allocated to the NW-HS group and 35 to the PS group. In the NW-HS group, we observed a significant reduction in the TNSS over time, at rates higher than those of the PS group ( <i>p</i>  < 0.001), as well as a significant reduction in the VNRS score at all observation times, and also at rates higher than those of the PS group ( <i>p</i>  < 0.001). The safety was good for all patients.</p><p><strong>Conclusion: </strong>The present trial documented the efficacy and safety of NW-HS in the treatment of nasal symptoms common to upper respiratory tract disorders. Most of the beneficial effects appeared as early as three days after the beginning of the treatment. In addition, compared to PS, NW-HS showed impressive results; thus, it may represent a safe and valuable option in the non-pharmacological therapy for rhinitis.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 3","pages":"1-8"},"PeriodicalIF":1.1,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12307079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144742041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Clinical Factors Associated with Self-reported Smell and Taste Disorders in Older Adults Hospitalized with COVID-19.","authors":"Letícia de Carvalho Palhano Travassos, Hemílio Fernandes Campos Coelho, Assel Muratovna Shigayeva Ferreira, Leandro Pernambuco","doi":"10.1055/s-0045-1801854","DOIUrl":"https://doi.org/10.1055/s-0045-1801854","url":null,"abstract":"<p><strong>Introduction: </strong>Complaints of smell and taste disorders are present in people with coronavirus disease 2019 (COVID-19), and they particularly impact older adults in their daily activities and quality of life. Understanding these disorders in this specific population is crucial due to the heightened susceptibility to decreased general health.</p><p><strong>Objective: </strong>To assess the prevalence and the factors associated with self-reported smell and taste disorders in older adults hospitalized with COVID-19.</p><p><strong>Methods: </strong>The present documentary and retrospective study used a dataset from the Paraíba State Department of Health based on individual record sheets of hospitalized people with severe acute respiratory syndrome (SARS), collected through a national form routinely applied in Brazilian hospitals. The complaints of smell and taste disorders were the dependent variables. The independent variables included the clinical outcomes and comorbidities. Data analysis involved descriptive statistics, the Fisher's exact test, and binary logistic regression. The confidence interval was 95%.</p><p><strong>Results: </strong>The sample comprised 5,014 older adults with a mean age of 74.50 ± 9.35 years, of both biological sexes, and most of them were admitted to the Intensive Care Unit (ICU), required non-invasive respiratory support, and experienced death. The prevalence of self-reported smell and taste disorders was 7.8% (95%CI = 7.2-8.8%) and 6.4% (95%CI = 5.6-7.1%) respectively. Smell disorders were less frequent among subjects admitted to the ICU and those who died, while taste disorders correlated with clinical outcomes such as fever, cough, sore throat, diarrhea, and comorbidities such as chronic neurological disease.</p><p><strong>Conclusion: </strong>Self-reported smell and taste disorders are present in almost 10% of older adults hospitalized with COVID-19, and they are associated with clinical outcomes and commorbities.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 3","pages":"1-10"},"PeriodicalIF":1.1,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12307078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144742043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immediate Effect of Neuromuscular Electrical Stimulation on Swallowing in Elderly People with Alzheimer's Dementia.","authors":"Eliene Giovanna Ribeiro, Cris Magna Dos Santos Oliveira, Aline Mansueto Mourão, Laélia Cristina Caseiro Vicente, Andréa Rodrigues Motta, Heitor Marques Honório, Giédre Berretin-Felix","doi":"10.1055/s-0045-1802579","DOIUrl":"https://doi.org/10.1055/s-0045-1802579","url":null,"abstract":"<p><strong>Introduction: </strong>Dysphagia affects a significant number of patients with Alzheimer's dementia. Neuromuscular electrical stimulation may be a promising resource for dysphagia rehabilitation in this population.</p><p><strong>Objective: </strong>To investigate the immediate effects of neuromuscular electrical stimulation on hyoid bone displacement, pharyngeal transit time, and swallowing safety in elderly people with Alzheimer's dementia.</p><p><strong>Methods: </strong>We evaluated 30 elderly individuals with an average age of 82.79 years, regardless of the stage of dementia and with reduced hyolaryngeal elevation, using the Northwestern Dysphagia Patient Check Sheet. Neuromuscular electrical stimulation was performed at the sensory and motor levels in the submental region during videofluoroscopy, with food being offered in solid, pudding, and liquid consistencies, and in portions of 5 mL and 10 mL. We applied Analysis of variance and the Friedman test, adopting a significance level of < 5%.</p><p><strong>Results: </strong>The comparison between the sensory and motor levels of stimulation showed that there was a significant difference in hyoid bone displacement for the mushy consistency, with neuromuscular stimulation at the motor level. There was no difference in the application of stimuli for the other consistencies regarding hyoid bone displacement, pharyngeal transit time, and the penetration and aspiration scale.</p><p><strong>Conclusion: </strong>In elderly people with Alzheimer's dementia, neuromuscular electrical stimulation at the motor level generated a reduction in hyoid bone displacement during swallowing of food with pudding consistency, with no effects on pharyngeal transit time or swallowing safety.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 3","pages":"1-7"},"PeriodicalIF":1.1,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12302327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144742042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vocal Cord Paralysis after Tracheal Intubation: An Overview of the Etiology and Associated Risk Factors.","authors":"Meerab Anwar, Komal Ashiq Hussain, Pervez Anwar","doi":"10.1055/s-0045-1808244","DOIUrl":"10.1055/s-0045-1808244","url":null,"abstract":"<p><strong>Introduction: </strong>Vocal cord paralysis (VCP) is a deprivation of motility and the dysfunction of the vocal cords due to a defect in the vagal nerve or recurrent laryngeal nerve (RLN). It also occurs due to mutilation in the cricoarytenoid joint or posterior commissure scarring after prolonged tracheal intubation. It is a disorder with an extensive range of etiologies reliant on its laterality pattern.</p><p><strong>Objective: </strong>To discuss the laterality pattern of VCP due to endotracheal intubation and its respective treatments, the associated etiologies, and the risk factors, to provide a new direction to physicians for its treatment and to avoid its occurrence.</p><p><strong>Data synthesis: </strong>We conducted a peer review of many of the articles published to date on VCP. An analysis of 967 patients from 5 studies determined that unilateral VCP (UVCP) is three times more frequent than bilateral VCP (BVCP). Furthermore, we analyzed 2,232 patients from 6 different studies that concluded surgery was the most common cause, followed by neoplastic diseases or malignancies. Another important though highly uncommon etiology of VCP is endotracheal intubation; however, it is disturbing for doctors as endotracheal intubation is a common procedure for general anesthesia.</p><p><strong>Conclusion: </strong>A variety of factors may cause VCP, including age, comorbidities, body mass index BMI, the duration of the intubation, the handling of the apparatus, operative time, and tracheal tube sizes. Preventive measures should be prioritized to avoid severe consequences, and intubation must be performed carefully in elderly people and in subjects with lower BMIs. Knowledge of the risk factors will help physicians customize intubation procedures in the future.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-7"},"PeriodicalIF":1.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12234165/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hearing Loss and Middle Ear Effusion in Nasopharyngeal Carcinoma Following Radiotherapy: Dose-Response Relationship and Normal Tissue Complication Probability Modeling.","authors":"Prem Wungcharoen, Anussara Prayongrat, Napadon Tangjaturonrasme","doi":"10.1055/s-0045-1805045","DOIUrl":"10.1055/s-0045-1805045","url":null,"abstract":"<p><p><b>Introduction</b>  Radiotherapy is the primary treatment for nasopharyngeal carcinoma. Radiation exposure to the cochlea and middle ear can cause hearing loss. <b>Objective</b>  To develop a multivariable normal tissue complication probability (NTCP) model to predict the risk of hearing impairment in nasopharyngeal cancer patients based on clinical and radiation dosimetry features and to identify the key factors associated with hearing loss. <b>Methods</b>  A retrospective review of 229 patients was conducted. We recorded the audiometry and presence of middle ear effusion (MEE) and compared findings before and after therapy. The factors included age, gender, signs and symptoms at presentation, tumor staging, prescribed dose at the tumor and high-risk nodal region, cochlea, and concurrent chemotherapy treatment. The model was formulated using multivariate logistic regression. <b>Results</b>  Age of more than 50 years, high primary staging, and dose at the cochlea > 43 Gy were major risk factors for sensorineural hearing loss. The final NTCP model for hearing loss comprised age and cochlea dose with an area under the curve (AUC) of 0.644; the predicted risk ranged from 15.84 to 44.52%. Locally advanced disease and cochlea dose greater than 44 Gy were risk factors for MEE; the predicted risk ranged from 20.42 to 51.99%. <b>Conclusion</b>  Age over 50, T stages 3 and 4, and > 43 Gy dose to the cochlea were significantly associated with an increased risk of sensorineural hearing loss and MEE. The developed NTCP model provides information to predict these risks, aiding in treatment planning and decision-making to avoid complications.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-9"},"PeriodicalIF":1.0,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12226208/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144575386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Auditory Processing in Stuttering Children: Behavioral and Electrophysiological Assessments.","authors":"Letícia Gregory, Milaine Dominici Sanfins, Piotr Henryk Skarzynski, Rafael Fabiano Machado Rosa, Paulo Ricardo Gazzola Zen, Pricila Sleifer","doi":"10.1055/s-0045-1804518","DOIUrl":"10.1055/s-0045-1804518","url":null,"abstract":"<p><p><b>Introduction</b>  Stuttering is a human communication disorder characterized by involuntary interruptions to speech flow. Electrophysiological tests and behavioral evaluations allow the neuroaudiological processes involved in stuttering to be investigated. <b>Objective</b>  To investigate group differences in the central auditory system using long-latency auditory evoked potentials, cognitive potentials, and behavioral assessments in children who stutter and compare them with fluent children. <b>Methods</b>  We assessed 18 children with stuttering and compared them with a control group of 18 children without speech or language impairment. All children were evaluated with pure tone and speech audiometry, acoustic immittance measures, brainstem auditory evoked potentials, long latency auditory evoked potentials, cognitive potentials, and behavioral tests of auditory processing - Random Gap Detection Test (RGDT), Dichotic Digit Test (DDT); Duration Pattern Test (DPT); Pediatric Speech Intelligibility (PSI); and Masking Level Difference (MLD). The Scale of Auditory Behaviors (SAB) questionnaire was also applied. <b>Results</b>  Children who stuttered had longer latencies of the P2 and P3 waves compared with the fluent group. There was no difference in P2 amplitudes, but there was a smaller P3 amplitude in children who stuttered, and they also showed significant alterations in the DDT and DPT. Furthermore, an association was found between increased P2 and P3 latency and SAB scores. <b>Conclusion</b>  The present study indicates that children who stutter tend to have decreased auditory ability in terms of central auditory processing, and this shows up psychophysically and on the SAB questionnaire.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-11"},"PeriodicalIF":1.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12213077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Qualitative Assessment of Quality and Readability of Patient-Directed Arabic Online Resources for Cochlear Implants in Children.","authors":"Saad A Sanad, Aseel M Mokhtar, Manar O Alharbi, Hisham B Alem, Afnan F Bukhari, Faisal Zawawi","doi":"10.1055/s-0045-1804516","DOIUrl":"10.1055/s-0045-1804516","url":null,"abstract":"<p><p><b>Objective</b>  To assess the readability and quality of various websites providing information on cochlear implantation (CI) in children in Arabic. <b>Methods</b>  The present is a cross-sectional online search. We conducted searches in the Arab language using the three most popular search engines, Yahoo, Google, and Bing, to search the topics of \"cochlear implant\" and \"cochlear implant in children.\" The information quality was evaluated through the DISCERN tool, while readability was examined using the OSMAN readability tool, which incorporated two readability metrics: the automated readability index (ARI) and the Läsbarhetsindex (LIX, reliability index). <b>Results</b>  In a study of 50 websites, the median Discerning the Quality of Information on Treatment Choices (DISCERN) quality score was 38, with an interquartile range (IQR) of 29 to 46, suggesting poor quality. Out of the 50 websites evaluated, only 10 were deemed to be of good quality. The median readability ARI was 8th grade (IQR: 6-9), which considered above the level of general population. Certain websites were found to be at or below the suggested 6th grade reading proficiency level. The median LIX was of 69 (IQR: 64-71), indicating that the text is very difficult. There was no correlation between readability and the DISCERN score. <b>Conclusions</b>  Our results suggest that many websites offering information on CIs for children in Arabic exhibit varying levels of quality and are composed in language surpassing the general population's reading ability. Developers should focus on improving the readability of their online content to ensure that the average reader can understand and benefit from the information.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-8"},"PeriodicalIF":1.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12213073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Characteristics of Nasal Fractures: An 11-year Retrospective Study.","authors":"Ramyar Farzan, Mohammadjavad Sharifian, Mohammad Tolouei, Siamak Rimaz, Sanaz Masoumi","doi":"10.1055/s-0044-1788314","DOIUrl":"10.1055/s-0044-1788314","url":null,"abstract":"<p><p><b>Introduction</b>  Nasal fractures are one of the most common diseases in the otorhinolaryngology emergency room that leads to significant complications. However, there is still no suitable method to prevent their occurrence, which may result from insufficient studies on their causes and related factors. <b>Objectives</b>  To describe the demographic features, pattern, time of consultation, and etiological factors of patients with different types of nasal fractures. <b>Methods</b>  We conducted a retrospective study of the records of patients with a diagnosis of nasal fracture treated between 2010 and 2021. The data included demographic characteristics, type of maxillofacial injury and associated lesions, complication rates, treatment modalities, and a description of the surgery. <b>Results</b>  We included 599 patients, mostly male subjects (81.6%) injured in a road accident (55.3%), with a mean age of 31.64 ± 14.65 years, and mean length of hospital stay of 2.27 ± 2.21 days. Most accompanying fractures were maxillary (38.5%), multiple (24.6%), and mandibular (23.1%). The mean length of hospital stay was statistically different according to the cause of the fracture ( <i>p</i>  = 0.036) and the types of treatment performed ( <i>p</i>  = 0.041). <b>Conclusion</b>  In general, trauma patients in the second to fourth decades of life and of the male gender are more prone to nasal fractures. Identifying the factors affecting the incidence of fractures enables the determination of the presentation patterns and the nature of the lesions to be evaluated. In addition, treatment evaluation and an analysis of the complication rate enable a more realistic interpretation of how patients are managed.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-7"},"PeriodicalIF":1.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12151707/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of Blood Thinners and Increased Nosebleeds during the Coronavirus Disease 2019 Pandemic.","authors":"Lucas Diniz Costa, Ana Paula Brandão Silva, Mariane Stagi Almada, Vanessa Pinheiro Adamo, Guilherme Irie Nakazora, Gustavo Rossoni Carnelli, Antonio Carlos Cedin","doi":"10.1055/s-0044-1791583","DOIUrl":"10.1055/s-0044-1791583","url":null,"abstract":"<p><p><b>Introduction</b>  In May 2020, the World Health Organization declared Brazil a new epicenter of the coronavirus pandemic. <b>Objective</b>  The present study aims to verify if the frequency of nasal bleeding and/or epistaxis in patients of a tertiary hospital was correlated with the pandemic of coronavirus disease 2019 (COVID-19) and with the use of anticoagulants. <b>Methods</b>  The analysis performed was retrospective from the database of the otorhinolaryngology service of a Brazilian tertiary hospital, comparing 2 periods: 1 from March 2020 to July 2021 comprising the peak of pandemic setting, and another from August 2021 to May 2022. We checked data on the average number of cases/month and on the use of anticoagulants. <b>Results</b>  In the period above mentioned, there were 61 cases of COVID-19-related epistaxis (from a total of 180 cases of nasal bleeding and/or epistaxis), with an average of 12 cases/month, demonstrating an increase in the frequency of cases at the institution, when compared to a study involving 343 cases from the same institution over a period of 42 months (October 2015-March 2019), in which the average was 8.1 cases/month. Among the patients with COVID-19 and nasal bleeding, 55 (90.17%) were using some type of anticoagulant at the time of bleeding: 41% were on subcutaneous heparin; 20% were on subcutaneous enoxaparin; 16.66% were receiving intravenous heparin on continuous infusion bomb (CIB); 6.66% were on extracorporeal membrane oxygenation (ECMO) associated with intravenous heparin on CIB; 4.99% were on oral rivaroxaban; and 1.66% are on oral apixaban. <b>Conclusion</b>  Our study's data confirmed the increase in the number of epistaxis cases and the use of anticoagulants in COVID-19 patients.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-3"},"PeriodicalIF":1.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12151705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}