International Archives of Otorhinolaryngology最新文献

{"title":"Analysis of Auditory Function before and after a Single Session of Hemodialysis in Patients with Chronic Kidney Disease.","authors":"Érica Alessandra Caldas, Patrick Rademaker Burke, Aline Gomes Bittencourt, Patricia Andréia Caldas, Eduardo Henrique Costa Rodrigues, Natalino Salgado Filho","doi":"10.1055/s-0044-1789196","DOIUrl":"10.1055/s-0044-1789196","url":null,"abstract":"<p><p><b>Introduction</b>  Hearing is a complex process that involves mechanical, chemical, and neurophysiological components. Changes in hearing can be caused by congenital or acquired etiological factors. Chronic kidney disease (CKD) is one of the causes of hearing loss. <b>Objective</b>  To compare auditory findings before and after a single session of hemodialysis in patients with chronic kidney disease. <b>Methods</b>  A clinical cross-sectional research was conducted with a sample of 23 individuals between 24 to 57 years of age with a diagnosis of CKD undergoing hemodialysis. Distortion product otoacoustic emission (DPOAE) and transient otoacoustic emission (TOAE) tests were performed before and after a session of hemodialysis. <b>Results</b>  The DPOAE test revealed that 26% of the participants had failure in both ears prior to dialysis and 30.4% had failure after dialysis. Comparing the DPOAE and TOAE tests before and after hemodialysis, a slight decrease was found in patients with \"fail\" results from the predialysis test to the postdialysis test, but the difference did not achieve statistical significance. <b>Conclusions</b>  No significant hearing changes assessed through otoacoustic emissions occurred after a single session of hemodialysis in the sample analyzed.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-6"},"PeriodicalIF":1.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12068942/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Auditory Brainstem Response Findings in Children with Level 1 Autism Spectrum Disorder: A Comparative Study.","authors":"Mariana de Medeiros Cardoso, Rudimar Dos Santos Riesgo, Pricila Sleifer","doi":"10.1055/s-0044-1792084","DOIUrl":"10.1055/s-0044-1792084","url":null,"abstract":"<p><p><b>Introduction</b>  Autism spectrum disorder is a pervasive developmental disorder characterized by deficits in communication and social interactions, as well as repetitive behavioral patterns. Understanding the relationship between auditory brainstem response and hearing is crucial, considering the importance of sensory function. Auditory brainstem response testing is a tool that evaluates the auditory system from periphery to brainstem in response to an acoustic stimulus, providing important information about the auditory pathways. <b>Objective</b>  To compare auditory brainstem response findings in children with autism spectrum disorder versus those of a control group. <b>Methods</b>  Cross-sectional, comparative study of 23 children (age 7-10 years) diagnosed with autism spectrum disorder and an age- and sex-matched control group of normal-hearing children with typical development. All participants underwent otoscopy, impedance audiometry, pure-tone audiometry, speech audiometry, and brainstem evoked response audiometry. <b>Results</b>  Statistically significant between-group differences were seen on comparison of the absolute latencies of waves III ( <i>p</i>  = 0.047) and V ( <i>p</i>  = 0.034), as well as interpeak intervals III to V ( <i>p</i>  = 0.048) and I to V ( <i>p</i>  = 0.036), with increased values in the study group. The sample was composed of 8.7% females and 91.3% males. <b>Conclusion</b>  In this sample, children with autism spectrum disorder showed increased auditory brainstem response latencies compared to the control group, suggesting auditory pathway impairment.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-7"},"PeriodicalIF":1.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12068944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distortion-product Otoacoustic Emissions in Diagnostic Versus Portable Equipment: A Comparison of Animal Models.","authors":"Gabriela Guenther Ribeiro Novanta, Vanessa Silva Pinto, Juliana Gusmão de Araújo, Lucieny Martins Serra, Andre Luiz Lopes Sampaio","doi":"10.1055/s-0044-1801314","DOIUrl":"https://doi.org/10.1055/s-0044-1801314","url":null,"abstract":"<p><p><b>Introduction</b>  Many protocols carried out in animal studies use equipment developed for humans. Therefore, the equipment available on the market must be known in detail, as well as how the criteria to be evaluated are presented. <b>Objective</b>  To analyze the existence of an association between the amplitude and signal-to-noise ratios of distortion-product otoacoustic emissions using two methodologies (diagnostic and portable/screening equipment) in animal models. <b>Methods</b>  Experimental study approved by the Animal Use Ethics Committee, with a sample of 28 female Wistar rats, which were subjected to anesthesia, manual otoscopy, and distortion-product otoacoustic emission (DPOAE) examination at 4 to 8 kHz with the 2 pieces of equipment. <b>Results</b>  The mean amplitude values with the ILO (Otodynamics Ltd., Hatfield, United Kingdom) and OtoRead equipment (Interacoustics A/S, Middelfart, Denmark) were respectively 20.5 dB and 7.1 dB at 4 kHz; 31.8 dB and 19.37 dB at 6 kHz; and 31.4 dB and 25.1 dB at 8 kHz. The mean signal-to-noise ratios with the ILO and OtoRead equipment were respectively 20.9 dB and 25.1 dB at 4 kHz; 35.8 dB and 37.0 dB at 6 kHz; and 39.7 dB and 40.6 dB at 8 kHz. There was no statistically significant difference in signal-to-noise ratios at 6 and 8 kHz. When the data were classified as normal/abnormal, 100% agreement was found between the methodologies. <b>Conclusion</b>  An association was found in the analysis of the mean signal-to-noise ratio at 6 and 8 kHz between the 2 methodologies (diagnosis and portable/screening equipment).</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-7"},"PeriodicalIF":1.0,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12058294/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Healthcare Providers' Knowledge on the Management of Pediatric Tracheostomy Emergencies.","authors":"Maha Alharbi, Rakan Almutairi, Salman Alotaibi, Mohammed Alqarny, Faisal AlMudhaibery, Hussein Etwadi, Yousef Aljathlany, Ahmed AlKhateeb, Abdulaziz AlEnazi","doi":"10.1055/s-0044-1791258","DOIUrl":"https://doi.org/10.1055/s-0044-1791258","url":null,"abstract":"<p><p><b>Introduction</b>  Morbidity and mortality related to tracheostomy can be reduced if complications are recognized immediately and managed effectively. Healthcare providers involved in the management of pediatric patients must be aware of tracheostomy-related emergencies, especially in life threatening situations. However, there is limited literature on this theme. <b>Objectives</b>  To assess the knowledge of healthcare providers in managing tracheostomy-related complications in pediatric patients. <b>Methods</b>  A descriptive, multicenter study was conducted among healthcare providers involved in the management of pediatric patients undergoing tracheostomy. Data were collected using electronic questionnaires, and participants' knowledge was evaluated using various clinical scenarios. <b>Results</b>  A total of 520 healthcare providers from different subspecialties with varying levels of experience were included. Over 50% of participants had never dealt with tracheostomy-related complications in pediatric populations, and 30.5% were unfamiliar with the function of the introducer/obturator. Furthermore, only 17.9% understood the purpose of stay sutures. Notably, when presented with different clinical scenarios, a significant knowledge gap was observed among the participants. <b>Conclusion</b>  There were significant gaps in knowledge among healthcare professionals regarding the management of tracheostomy-related emergencies in the pediatric population. Education on this topic is essential among healthcare professionals. This needs to be addressed to maximize patient safety. Further studies are recommended.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-9"},"PeriodicalIF":1.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12037218/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144006200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of Surgical and Conservative Approaches to Recurrent Thyroglossal Duct Cysts: A Literature Review.","authors":"Barbara Klyslie Kato, Leticia Souza Rego, Pedro Bizarro Dos Santos, Flavio Carneiro Hojaij","doi":"10.1055/s-0044-1789613","DOIUrl":"https://doi.org/10.1055/s-0044-1789613","url":null,"abstract":"<p><p><b>Introduction</b>  The management of recurrent thyroglossal duct cysts poses persistent challenges. The present review assesses chemical ablations and surgical re-interventions as strategies for recurrence. However, limited comparative studies exist to determine the optimal approach and follow-up outcome. <b>Objectives</b>  The aim of the current study is to conduct a review gathering evidence from the literature to analyze and synthesize the safest and most effective approaches for treating recurrent thyroglossal duct cysts. <b>Methods</b>  The present study aims to comprehensively search electronic databases, including the Latin American and Caribbean Literature in Health Sciences (Literatura Latino-Americana e do Caribe em Ciências da Saúde, LILACS, in Portuguese), the database of the <i>Journal of the American Medical Association</i> (JAMA), SciVerse Scopus, Virtual Health Library (Biblioteca Virtual em Saúde, BVS, in Portuguese), and PubMed, for articles on recurrent thyroglossal duct cysts. The selected articles include patients with recurrent cysts, cover publications from 2000 to 2022, describe clinical and/or surgical interventions, and ensure the safety and efficacy of the analyzed approach. <b>Results</b>  The present review included 9 studies, involving a cohort of 278 patients. Out of these patients, 143 underwent surgical interventions and 135 underwent chemical ablations (82 using ethanol and 53 with OK-432). <b>Conclusion</b>  Conservative management of recurrent thyroglossal duct cysts is a growing trend, albeit requiring further refinements. This approach presents potential advantages, including decreased recurrence rates, shorter surgical duration, cost-effectiveness, and expedited recovery. Nevertheless, surgical intervention remains the preferred therapeutic choice owing to its established efficacy and widespread familiarity. The projected therapeutic approach shifts for thyroglossal duct cysts as conservative treatment gains substantiated benefits. <b>Systematic Review Registration</b> : The International Prospective Register of Systematic Reviews (PROSPERO) does not accept scoping reviews, literature reviews, or mapping reviews.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-6"},"PeriodicalIF":1.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12037215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143998330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the Diagnosis of Pediatric Dizziness in a Tertiary Care Hospital: The Complementary Role of Vestibular and Neurological Evaluations.","authors":"Ahmed Khater, Wafaa Samir Mohamed, Diana Hanna, Yostina Adel Abdelmalak, Nahla Gad","doi":"10.1055/s-0044-1801318","DOIUrl":"https://doi.org/10.1055/s-0044-1801318","url":null,"abstract":"<p><p><b>Introduction</b>  Pediatric dizziness is not a rare symptom, and it has a significant impact on the child's psychophysical wellbeing and quality of life. There are diverse etiologies of dizziness in children; however, it is challenging to diagnose. Vestibular and neurological assessments are crucial in the diagnosis of pediatric dizziness. <b>Objective</b>  To outline the most common etiologies of dizziness in children and to investigate the complementary role of the vestibular and neurological evaluations in the assessment of dizzy children. <b>Methods</b>  We conducted a case-control study including 40 children with a complaint of dizziness and 40 healthy children as the control group. We assessed their full medical history audiovestibular function through pure tone audiometry, videonystagmography examination, cervical vestibular evoked myogenic potentials, the results of video head impulse tests, as well as their electroencephalograms and brain magnetic resonance imaging scans. <b>Results</b>  The mean age of the 40 children who were presented with dizziness was of 13.65 years. Migraine was found to be the commonest cause of vertigo (27.5%), while benign paroxysmal vertigo of childhood was detected in 17.5%, and central nervous system causes, in 12.5%. The diagnosis could not be ascertained in 9 (22.5%) patients. <b>Conclusion</b>  The diagnosis of the etiologies of pediatric dizziness is challenging; however, detailed medical history, a comprehensive examination, a multidisciplinary approach, along with full vestibular and neurological assessments, are essential to reach an accurate diagnosis.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-8"},"PeriodicalIF":1.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144020989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Esthetic and Functional Outcomes of Superficial Parotidectomy Comparing Three Reconstruction Techniques: An Interventional Clinical Study.","authors":"Sherif Mohammad Askar, Abd ElRaof Said Mohamed, Tamer Oraby, Ibrahim Khaled, Mahmoud Megahed, Ali Awad","doi":"10.1055/s-0044-1788911","DOIUrl":"https://doi.org/10.1055/s-0044-1788911","url":null,"abstract":"<p><p><b>Introduction</b>  Preauricular defect is one of the main concerns after superficial parotidectomy. Plastic surgeons have described many filling techniques to overcome the problem. <b>Objective</b>  To discuss three reconstruction techniques after superficial parotidectomy: partial-thickness, superiorly based sternocleidomastoid muscle flap; en-bloc fat graft; and platelet-rich fibrin gel, with a comparison of aesthetic and functional outcomes. <b>Methods</b>  The present study included 29 adult patients submitted to reconstruction after superficial parotidectomy by partial-thickness, superiorly based sternocleidomastoid muscle flap, en-bloc fat graft, and platelet-rich fibrin gel. A subjective evaluation of the facial nerve functions was conducted through a visual analog scale (VAS) with scores from 0 to 5, which was completed by the patient, a close relative, and 3 blinded staff members. <b>Results</b>  Regarding the VAS, in the comparison of the 3 groups at the sixth and twelfth postoperative months, the fat-graft group reported the highest mean values for satisfaction (3.4 ± 1.1 and 3.83 ± 0.97 respectively). The fat-graft group also showed highly significant differences when compared with the groups submitted to the sternocleidomastoid muscle flap ( <i>p</i>  = 0.0001) and the platelet-rich fibrin gel techniques ( <i>p</i>  = 0.016). <b>Conclusion</b>  Parotidectomy with immediate reconstruction of the surgical defect through an en-block fat graft provides better esthetic outcomes than sternocleidomastoid muscle flap and platelet-rich fibrin gel after one year. The patients submitted to the sternocleidomastoid muscle flap and fat-graft techniques reported minimal surgical site morbidity and a lower chance of developing Frey syndrome. The fat graft resulted in the best degree of cosmetic satisfaction, with minimal morbidity. Fat overcorrection is recommended.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-7"},"PeriodicalIF":1.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isotretinoin in Thick-Skin Rhinoplasty: A Review.","authors":"Rafael Pessoa Porpino Dias, Jose Luiz Teixeira Rodrigues, Maíra Said Dias Jabour, Raíssa de Oliveira E Albuquerque, Henrique de Almeida Friedrich, Michele Sander Westphalen, Carlos Alberto Caropreso","doi":"10.1055/s-0044-1801319","DOIUrl":"https://doi.org/10.1055/s-0044-1801319","url":null,"abstract":"<p><p><b>Introduction</b>  Thick-skinned patients are prevalent in the general population worldwide and represent a challenge for the rhinoplasty surgeon. The use of oral isotretinoin before and/or after surgery is a possible adjuvant treatment that can facilitate intraoperative management and improve results in the postoperative stages; however, there are still questions about its effects in the long-term. <b>Objective</b>  To evaluate the advantages and best practices for orally administrated isotretinoin in thick-skin rhinoplasty based on the current literature. <b>Methods</b>  An advanced search was conducted until August 31st, 2023, on the PubMed, Cochrane Library, ClinicalTrials.gov, Embase, and LILACS databases with the keywords <i>rhinoplasty</i> and <i>isotretinoin</i> . Sixteen articles were reviewed and 4 met the inclusion criteria, with a total of 371 patients. Meta-analysis of the data collected was not possible due to heterogeneity among papers. <b>Conclusion</b>  Isotretinoin can be a safe drug, and its use in rhinoplasty varies widely, although all studies reported a low-dose oral regime for up to 6 months. The medication use is well-established in thick-skin rhinoplasty. Small doses after the procedure can improve patient satisfaction and the quality and thickness of the skin in the first 6 months of postsurgery. After 6 months, studies with a control group did not show a significant difference in patient satisfaction rates. A strong framework and specific surgical maneuvers may be more important than isotretinoin for better outcomes in thick-skin rhinoplasty.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-6"},"PeriodicalIF":1.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020492/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Analysis Between Body Composition and Vertigo Post-Coronavirus Disease 2019 Patients.","authors":"Luciana Lozza de Moraes Marchiori, Glória de Moraes Marchiori, Licia Sayuri Tanaka Okamura, Daiane Soares de Almeida Ciquinato, Braulio Henrique Magnani Branco","doi":"10.1055/s-0044-1791729","DOIUrl":"https://doi.org/10.1055/s-0044-1791729","url":null,"abstract":"<p><p><b>Introduction</b>  An association between the sensation of vertigo, and body composition has not been investigated in post-coronavirus disease 2019 (COVID-19) patients. <b>Objective</b>  To evaluate the probable association between the sensation of vertigo and body composition-as amount of fat, bone, and muscle-in post-COVID-19 patients. <b>Methods</b>  Cross-sectional study with a sample of post-COVID-19 patients who responded to the visual analog scale (VAS) and the Dizziness Handicap Inventory (DHI). Clinical assessment and electrical bioimpedance were used to determine body composition. <b>Results</b>  There were 105 participants evaluated, 61% (n = 64) of whom were male, aged 49.5 ± 11.7 years, with an average height of 165.6 ± 19.9 cm, body weight of 87.6 ± 20 kg, and body mass index (BMI) of 31.1 ± 5.4 kg/m. The prevalence of self-reported vertigo was 51.4% (n = 54); of these, 11.4% (n = 12) related vertigo before the diagnosis of COVID-19, and 40% (n = 42) related vertigo during or after COVID-19. Furthermore, 37.2% (n = 39) of the sample reported that vertigo persisted after medical discharge. In the comparative analysis, the data showed a significant difference between the groups with and without vertigo for height ( <i>p</i>  = 0.001), body mass ( <i>p</i>  = 0.006), body water ( <i>p</i>  = 0.001), lean mass ( <i>p</i>  = 0.002), fat-free mass ( <i>p</i>  = 0.001), and musculoskeletal mass ( <i>p</i>  = 0.001). <b>Conclusion</b>  There was a significant association between body composition and the complaint of vertigo in post-COVID-19 patients, suggesting that these aspects should be considered when assessing and can contribute to the construction of knowledge about long COVID.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-8"},"PeriodicalIF":1.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Preoperative Thyroid-Stimulating Hormone Levels in the Prediction of Thyroid Hormone Replacement after Hemithyroidectomy.","authors":"Ramona Paula Fernandes Reckziegel, Lenara Golbert, Erika Laurini de Souza Meyer","doi":"10.1055/s-0045-1801852","DOIUrl":"https://doi.org/10.1055/s-0045-1801852","url":null,"abstract":"<p><p><b>Introduction</b>  Hemithyroidectomy is performed for the treatment of symptomatic unilateral benign nodules, cytologically indeterminate nodules, and some cases of well-differentiated thyroid cancer. <b>Objective</b>  To evaluate the frequency of postlobectomy thyroid hormone replacement (THR), and to analyze the clinical-pathological factors predicting L-thyroxine (T4) use in patients undergoing hemithyroidectomy. <b>Methods</b>  We conducted an observational, retrospective study in which clinical, biochemical, and anatomopathological parameters were analyzed and correlated with the need for THR after thyroid lobectomy. <b>Results</b>  The frequency of postoperative THR was 63%. The preoperative thyroid-stimulating hormone (TSH) level was an important predictor of postoperative THR. When stratifying preoperative TSH levels, the frequencies of T4 replacement in each TSH quartile varied, being more frequent with increasing presurgical TSH levels ( <i>p</i>  = 0.029). The preoperative cutoff that maximized sensitivity and specificity for the development of hypothyroidism was 1.21 μIU/mL. <b>Conclusion</b>  Our results demonstrated a significant frequency of postlobectomy THR. Higher preoperative TSH is a strong risk factor for postsurgical hypothyroidism, and even lower preoperative levels within the normal references do not exclude the risk of thyroid hormone use after thyroid lobectomy.</p>","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"29 2","pages":"1-6"},"PeriodicalIF":1.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}