International Archives of Otorhinolaryngology最新文献_第2页

Economic Burden of Otitis Media Globally and an Overview of the Current Scenario to Alleviate the Disease Burden: A Systematic Review. 全球中耳炎的经济负担及减轻疾病负担的现状概述：系统回顾。

IF 1

International Archives of Otorhinolaryngology Pub Date : 2024-07-05 eCollection Date: 2024-07-01 DOI: 10.1055/s-0043-1767802

Ragini Bhatia, Anil Chauhan, Monika Rana, Kulbir Kaur, Pranita Pradhan, Meenu Singh

{"title":"Economic Burden of Otitis Media Globally and an Overview of the Current Scenario to Alleviate the Disease Burden: A Systematic Review.","authors":"Ragini Bhatia, Anil Chauhan, Monika Rana, Kulbir Kaur, Pranita Pradhan, Meenu Singh","doi":"10.1055/s-0043-1767802","DOIUrl":"10.1055/s-0043-1767802","url":null,"abstract":"Introduction The prevalence of otitis media (OM) is substantial all over the world. Epidemiological data related to the economic burden of OM globally is minimal. The present systematic review was undertaken to estimate the economic burden of this disease in various parts of the world. Objectives An extensive literature search was done using PRISMA guidelines to identify relevant studies that estimated the economic burden of OM in monetary terms. The databases searched were PubMed Central, Ovid, and Embase. The cost estimation was done for one specific year and then compared considering the inflation rate. Data Synthesis The literature search led to the inclusion of 10 studies. The studies evaluated direct and indirect costs in monetary terms. Direct costs (health system and patient perspective) ranged from USD (United States Dollar) 122.64 (Netherlands) to USD 633.6 (USA) per episode of OM. Looking at only the patient perspective, the costs ranged from USD 19.32 (Oman) to USD 80.5 (Saudi Arabia). The total costs (direct and indirect) ranged from USD 232.7 to USD 977 (UK) per episode of OM. The economic burden per year was highest in the USA (USD 5 billion). The incidence of OM episodes was found more in children < 5 years old. Introduction of pneumococcal conjugate vaccines decreased the incidence in children and now the prevalence in adults is of concern. Conclusion The economic burden of OM is relatively high globally and addressing this public health burden is important. Approaches for the prevention, diagnosis, and treatment should be undertaken by the health system to alleviate this disease burden.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11226269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141554690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hearing Function after CyberKnife for Vestibular Schwannoma: A Systematic Review. 前庭许旺瘤赛博刀治疗后的听觉功能：系统性综述。

IF 1

International Archives of Otorhinolaryngology Pub Date : 2024-07-05 eCollection Date: 2024-07-01 DOI: 10.1055/s-0044-1787736

Matheus Pedrosa Tavares, Fayez Bahmad

{"title":"Hearing Function after CyberKnife for Vestibular Schwannoma: A Systematic Review.","authors":"Matheus Pedrosa Tavares, Fayez Bahmad","doi":"10.1055/s-0044-1787736","DOIUrl":"10.1055/s-0044-1787736","url":null,"abstract":"Introduction CyberKnife (CK) radiosurgery is a treatment strategy for vestibular schwannoma (VS). Objectives To evaluate hearing preservation (HP) after CK for VS. Data Synthesis The study was conducted following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement, and it was registered at the International Prospective Register of Systematic Reviews (PROSPERO, under number CRD42021250300). The inclusion criteria were based on the population, intervention, comparison, outcome, timing and study design (PICOTS) strategy: population - patients with VS; intervention - CK; Comparison - none; Outcome - serviceable HP defined by Gardner and Robertson as grades I or II, or by the American Academy of Otolaryngology and Head and Neck Surgery as classes A or B; timing - mean follow-up longer than 1 year; and study design - retrospective or prospective studies. The exclusion criteria were: studies not published in English; studies published before January 2000 and after October 2021; and studies only including patients with neurofibromatosis type 2 or submitted to a previous treatment. The PubMed/MEDLINE, EMBASE, Web of Science, Cochrane Library, LILACS, and IBECS databases were used and last searched on October 27th, 2021. Statistical heterogeneity was assessed using I 2 statistics. The appraisal checklist was used to assess the risk of bias in the included studies. A total of 222 studies were analyzed, and 13 were included in the synthesis, which represents 493 participants with serviceable hearing before intervention. The mean HP rate after CK using a random effects model was of 68% (95% confidence interval [95%CI]: 59-76%) at a mean follow-up of 42.96 months. Conclusion The longer follow-up period was associated with a lower HP rate after CK radiosurgery for VS in the qualitative synthesis.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11226254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141554731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anatomical Measurement as a Reference for Functional Endoscopic Sinus Surgery Based on CT Scans and Dissections. 基于 CT 扫描和解剖的解剖测量作为功能性内窥镜鼻窦手术的参考。

IF 1

International Archives of Otorhinolaryngology Pub Date : 2024-07-05 eCollection Date: 2024-07-01 DOI: 10.1055/s-0043-1777447

Andressa Vinha Zanuncio, Flávia Gontijo Amaral, Marcell de Barros Duarte Pereira, Flávio Barbosa Nunes, Roberto Eustáquio Santos Guimarães

{"title":"Anatomical Measurement as a Reference for Functional Endoscopic Sinus Surgery Based on CT Scans and Dissections.","authors":"Andressa Vinha Zanuncio, Flávia Gontijo Amaral, Marcell de Barros Duarte Pereira, Flávio Barbosa Nunes, Roberto Eustáquio Santos Guimarães","doi":"10.1055/s-0043-1777447","DOIUrl":"10.1055/s-0043-1777447","url":null,"abstract":"Introduction Diseases of the paranasal sinuses, nasal cavities, and those related to the skull base can be treated with nasal endoscopic surgery. Anatomical references are essential to safely perform these surgeries. Objective To measure and compare the distance from the posterior wall of the maxillary sinus to the anterior skull base in cadavers and on computed tomography (CT) scans to determine a measurement as an anatomical reference in imaging exams for sinus and anterior skull base surgery. Methods In dissections and CT scans, we took measurements from the most upper and medial point of the posterior wall of the maxillary sinus (point A) to the point where the skull base deflects and the anterior sphenoid wall is formed (Δ 90°; point B), in the right and left nasal cavities. We used 51 cadavers aged ≥ 18 years in the present research. Results The measurements obtained from CT scans and dissections were greater than 1.5 cm in all cadavers, and they were positively correlated. The 1-cm increase in the AB-tomography measurement corresponded to the 1.08-cm increase to the right and 1.07-cm to the left in the AB-dissection measurement. Conclusion The CT measurements may be considered a reliable tool to promote safe and effective access to the paranasal sinuses, matching the distance that should be dissected until the anterior base of the skull.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11226291/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141554687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inner Ear Mixed Hearing Loss. 内耳混合性听力损失

IF 1

International Archives of Otorhinolaryngology Pub Date : 2024-07-05 eCollection Date: 2024-07-01 DOI: 10.1055/s-0044-1786830

Pedro Luiz Mangabeira Albernaz

引用次数: 0

Study of Otorhinolaryngological Manifestations in Symptomatic COVID-19-Positive Patients at Tertiary Health Care Hospital: A Cross-sectional Study. 三级医疗保健医院有症状的 COVID-19 阳性患者耳鼻喉科表现的研究：横断面研究。

IF 1

International Archives of Otorhinolaryngology Pub Date : 2024-07-05 eCollection Date: 2024-10-01 DOI: 10.1055/s-0044-1786831

Disha Amar Methwani, Nitin Deosthale, Sonali Khadakkar, Kanchan Dhote, Vivek Harkare

{"title":"Study of Otorhinolaryngological Manifestations in Symptomatic COVID-19-Positive Patients at Tertiary Health Care Hospital: A Cross-sectional Study.","authors":"Disha Amar Methwani, Nitin Deosthale, Sonali Khadakkar, Kanchan Dhote, Vivek Harkare","doi":"10.1055/s-0044-1786831","DOIUrl":"10.1055/s-0044-1786831","url":null,"abstract":"Introduction The coronavirus disease 2019 (COVID-19), also referred to as the 2019 novel coronavirus, is caused by a single-stranded positive-sense RNA virus. This infectious agent spreads through respiratory routes, primarily utilizing aerosols. In our study, we shed light on ear, nose, and throat (ENT) manifestations, which can be considered as prognostic clinical biomarkers to reduce forthcoming complications among such critically ill patients. This makes it feasible for researchers to investigate or fetch early diagnosis in such cases with ease without the use of large, extensive hospital-base setups. Objective To study the otorhinolaryngological (ENT) manifestations in symptomatic COVID-19 patients. Methods From January to December 2021, a cross-sectional observational study was conducted at the Department of ENT of a tertiary care hospital in central India. All eligible symptomatic COVID-19 patients admitted to this institution during the study period were consecutively enrolled. The Institutional Ethics Committee gave its permission for the project. Results Out of the total of 1,375 patients, 78% of the patients diagnosed with COVID exhibited symptoms related to the ENT, while the remaining 22% did not display any ENT manifestations. Anosmia (71.2%), sore throat (55.62%), headache (44.3%), and loss of taste (66.3%) were among the most common ENT symptoms. Conclusion The present study highlights ENT manifestations, which play a crucial role in the early diagnosis of COVID-19 patients, ensuring faster treatment and isolation for better containment of the disease. Symptomatic treatment has shown efficacy, but objective tests are needed to prevent overestimation, understand pathogenesis, and enhance treatment.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11511268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142499815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Peripheral Auditory Pathway and ABR Characterization in Adults with Williams Syndrome. 威廉斯综合征成人的外周听觉通路和 ABR 特征。

IF 1

International Archives of Otorhinolaryngology Pub Date : 2024-07-05 eCollection Date: 2024-07-01 DOI: 10.1055/s-0044-1785457

Jacqueline Aquino do Nascimento, Liliane Aparecida Fagundes Silva, Alessandra Gianella Samelli, Carla Gentile Matas

{"title":"Peripheral Auditory Pathway and ABR Characterization in Adults with Williams Syndrome.","authors":"Jacqueline Aquino do Nascimento, Liliane Aparecida Fagundes Silva, Alessandra Gianella Samelli, Carla Gentile Matas","doi":"10.1055/s-0044-1785457","DOIUrl":"10.1055/s-0044-1785457","url":null,"abstract":"Introduction Williams syndrome (WS) is a genetic disorder caused by a microdeletion in chromosome 7, affecting ∼ 28 genes. Studies have demonstrated conductive losses seemingly related to the absence of the elastin gene and mild to profound sensorineural losses due to cochlear fragility. Objective To characterize and compare the peripheral auditory system and auditory brainstem response (ABR) of adults with WS and neurotypical adults matched by age and gender. Methods We conducted a cross-sectional observational study with 30 individuals of both sexes, aged 18 to 37 years - 15 of them with WS (study group) and 15 with neither the syndrome nor hearing complaints (control group), matched for sex and age. The subjects underwent pure-tone and speech audiometry, acoustic immittance, transient-evoked otoacoustic emissions (TEOAEs), and ABR. Results Early-onset sensorineural hearing loss was found in 53.3% of the study sample, mostly mild, occurring above 3 kHz. The TEOAEs were absent in 53.3% of assessed subjects; for those in whom they were present, the signal-to-noise responses were significantly lower than in the control group. In the ABR, increased absolute latencies were observed in waves I and III. Conclusion Individuals with WS have early and progressive cochlear impairments, mainly affecting the basal region of the cochlea. They may have low brainstem changes which seem to begin in adulthood.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11226263/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141554734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accuracy of Diagnosis of Benign Vocal Fold Lesions among Ear, Nose, and Throat Residents. 耳鼻喉科住院医师诊断良性声带褶皱病变的准确性。

IF 1

International Archives of Otorhinolaryngology Pub Date : 2024-07-05 eCollection Date: 2024-10-01 DOI: 10.1055/s-0044-1787168

Mohamed Mesfer Alessa, Sultan Bin Obaid, Faisal Aldayel, Rakan Almetary, Khaled Alhussinan, Hassan Assiri, Mohamed Farahat

{"title":"Accuracy of Diagnosis of Benign Vocal Fold Lesions among Ear, Nose, and Throat Residents.","authors":"Mohamed Mesfer Alessa, Sultan Bin Obaid, Faisal Aldayel, Rakan Almetary, Khaled Alhussinan, Hassan Assiri, Mohamed Farahat","doi":"10.1055/s-0044-1787168","DOIUrl":"10.1055/s-0044-1787168","url":null,"abstract":"Introduction Benign vocal fold lesions (BVFLs) disrupt the superficial lamina propria, impacting vocal fold pliability. Investigating the diagnostic competency of ear, nose, and throat (ENT) residents in identifying BVFLs, we hypothesize that factors such as residency year, subspecialty focus, and training center influence diagnostic accuracy. Objectives To assess the accuracy of diagnosis of BVFLs among ENT residents and to correlate diagnostic accuracy with the year of residency. Methods An observational cross-sectional study included all ENT residents in Saudi Arabia. It was performed in August and September 2021 using a self-administered online questionnaire that assessed demographic variables and included three images with open-ended questions on diagnosing vocal fold lesions. Results A total of 61 ENT residents (62.3% male) were included in this study. The images of vocal fold cyst, vocal fold polyp, and vocal fold nodule were correctly diagnosed by 60.7%, 88.5%, and 91.8% of residents, respectively. There was a correlation between the year of residency and the accuracy of diagnosing a vocal fold cyst ( p = 0.029). Residents interested in laryngology correctly diagnosed all three lesions more frequently than other residents. Conclusion The ability of residents to diagnose vocal fold cysts was moderate. In particular, the senior residents were able to diagnose polyps and nodules with excellent accuracy.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11511276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142499794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Computed Tomography in the Diagnosis of Congenital Sensorineural Hearing Loss. 计算机断层扫描在诊断先天性感音神经性听力损失中的作用。

IF 1

International Archives of Otorhinolaryngology Pub Date : 2024-06-07 eCollection Date: 2024-07-01 DOI: 10.1055/s-0044-1786827

Mauricio Buschle, Rogerio Hamerschmidt, Jorge Eduardo Fouto Matias, Otavio Pereira Lima Zanini, Luiz Otavio de Mattos Coelho, Jose Fernando Polanski

{"title":"The Role of Computed Tomography in the Diagnosis of Congenital Sensorineural Hearing Loss.","authors":"Mauricio Buschle, Rogerio Hamerschmidt, Jorge Eduardo Fouto Matias, Otavio Pereira Lima Zanini, Luiz Otavio de Mattos Coelho, Jose Fernando Polanski","doi":"10.1055/s-0044-1786827","DOIUrl":"10.1055/s-0044-1786827","url":null,"abstract":"Introduction One of the paths in the investigation of congenital sensorineural hearing loss (CSNHL) is to try to characterize its etiology through the inner ear evaluation using high resolution computer tomography (CT) scans. With minor malformation, it is not always possible for a simple visual inspection to recognize if the structure in the inner ear is normal or not. Objective To verify if measurements of the inner ear are predictive of sensorineural hearing loss (SNHL) and suggest cutoff points of size limits. Methods Retrospective cross-sectional study of inner ear CT scan measurements of 214 patients, 50 with congenital SNHL (CSNHL) and 164 acquired SNHL (ASNHL) (control group). Results In the CSNHL group, central bony island (CBI) were 0.48 mm smaller ( p < 0.001), cochlear nerve aperture was (CNA) 0.10 mm smaller ( p < 0.001), and cochlea height was (CH) 0.15 mm smaller ( p < 0.001). Vestibular aqueduct (VA) and cochlea width (CW) were similar between groups (0.70 vs 0.72, p = 0.19, and 7.20 vs 7.15 p = 0.23). The predictive cutoff points for CSNHL were CBI = 3.6 mm, CAN = 1.4 mm, CH = 3.4 mm, CW = 7.0 mm, and VA = 0.9 mm. Conclusion Congenital sensorineural hearing loss determined a decrease in CBI, opening of the cochlear nerve (OCN), and CW. Thus, these measures, at the cutoff points indicated, should make us aware of the diagnosis of congenital hearing loss.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11226303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141554738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Juvenile Nasopharyngeal Angiofibroma: A Series of 96 Surgical Cases 幼年鼻咽血管纤维瘤：96 例手术系列病例

IF 1.1

International Archives of Otorhinolaryngology Pub Date : 2024-06-04 DOI: 10.1055/s-0043-1777293

A. Felippu, Erica Batista Fontes, A. W. D. Felippu, Bruna Coelho Ellery, Ana Carolina Silveira de Oliveira, André Vicente Guimarães, Filippo Cascio, A. Felippu

{"title":"Juvenile Nasopharyngeal Angiofibroma: A Series of 96 Surgical Cases","authors":"A. Felippu, Erica Batista Fontes, A. W. D. Felippu, Bruna Coelho Ellery, Ana Carolina Silveira de Oliveira, André Vicente Guimarães, Filippo Cascio, A. Felippu","doi":"10.1055/s-0043-1777293","DOIUrl":"https://doi.org/10.1055/s-0043-1777293","url":null,"abstract":"\u0000 Introduction Juvenile nasopharyngeal angiofibroma (JNA) is a benign vascularized tumor that affects almost exclusively male adolescents. Surgery is the treatment of choice for JNA.\u0000 Objectives The present study is a 42-year retrospective review of a series of JNA cases treated surgically without previous embolization.\u0000 Methods The present is a retrospective, descriptive study based on medical records of 96 patients with JNA who underwent microscopic or endoscopic excision without previous embolization from 1978 to 2020 in a single institution. The patients were categorized according to the Andrews et al. stage, and data were collected on age, gender, tumor staging, surgical approach, affected side, and outcome.\u0000 Results All patients were male, with an average age of 17 years. The predominant tumor stage consisted of type II, with 52.1%. A total of 33.3% of the patients were submitted to the microscopic technique and 66.7%, to the endonasal technique. The rate of intraoperative blood transfusion was of 17.7%.\u0000 Conclusion The present study reinforces that resection of JNA in various stages is viable without previous artery embolization.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141267566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Platelet-Rich Plasma in Fat Graft Type-1 Tympanoplasty – Should We or Should We Not? 富血小板血浆在脂肪移植 1 型鼓室成形术中的应用--应该还是不应该？

IF 1.1

International Archives of Otorhinolaryngology Pub Date : 2024-06-04 DOI: 10.1055/s-0044-1787169

B. Choudhury, Palak Gupta, Saptarshi Mandal, Vidhu Sharma, Kapil Soni, D. Kaushal

{"title":"Platelet-Rich Plasma in Fat Graft Type-1 Tympanoplasty – Should We or Should We Not?","authors":"B. Choudhury, Palak Gupta, Saptarshi Mandal, Vidhu Sharma, Kapil Soni, D. Kaushal","doi":"10.1055/s-0044-1787169","DOIUrl":"https://doi.org/10.1055/s-0044-1787169","url":null,"abstract":"\u0000 Introduction Fat grafts have been in used since 1962 for small central perforations, with a success rate ranging from 86 to 100%. Platelet-rich plasma (PRP) containing platelet concentrations greater than 1 million platelets/μL assist the healing process by various means. Current data suggests improved healing when tympanoplasty is performed using temporalis fascia grafts if PRP is added during surgery.\u0000 Objective To assess the effect of PRP on fat grafts in small and moderate-sized central perforations.\u0000 Methods The present prospective observational study was conducted with 36 patients who underwent fat graft tympanoplasty with PRP under local anesthesia. Clinical and audiological observations were carried out after 4, 8, and 12 weeks, and a statistical analysis of the observations was performed.\u0000 Results We assessed 23 patients with small central perforations and 11 patients with moderate central perforations. An overall success rate of 76.4% was observed, with an 82.6% success rate among patients with small central perforations and 63.6% among those with moderate central perforations. There was no statistically significant difference in the uptake regarding the location of the perforation, but a statistically significant difference was found in terms of hearing improvement following the procedure.\u0000 Conclusion The morbidity of conventional tympanoplasty in cases of small-to-moderate central perforations in patients with chronic otitis media vis a vis the results of the procedure needs to be revisited, as in the present study fat grafts placed with PRP under local anesthesia could lead to surgical and audiological outcomes that are as good as those reported in the literature.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141266927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0