International Archives of Otorhinolaryngology最新文献_第10页

Comparison of Pre- and Posttreatment Airway Volume in Patients with Temporomandibular Joint Disorders Treated with Ultra-Low Frequency Transcutaneous Electrical Nerve Stimulation Using Cone Beam Computed Tomography. 锥形束计算机断层扫描超低频经皮神经电刺激治疗颞下颌关节疾病前后气道容积的比较。

IF 1.1

International Archives of Otorhinolaryngology Pub Date : 2023-10-23 eCollection Date: 2023-10-01 DOI: 10.1055/s-0042-1758207

Rhea Susan Verghese, Renju Jose, Anu Ramachandran, Aravind M Shanmugham, Priya K Nair, Krishna S Kumar, Beena R Varma

{"title":"Comparison of Pre- and Posttreatment Airway Volume in Patients with Temporomandibular Joint Disorders Treated with Ultra-Low Frequency Transcutaneous Electrical Nerve Stimulation Using Cone Beam Computed Tomography.","authors":"Rhea Susan Verghese, Renju Jose, Anu Ramachandran, Aravind M Shanmugham, Priya K Nair, Krishna S Kumar, Beena R Varma","doi":"10.1055/s-0042-1758207","DOIUrl":"10.1055/s-0042-1758207","url":null,"abstract":"Introduction Temporomandibular joint disorders (TMD) present with a multitude of symptoms that can range from headaches to shoulder pain. Patients frequently present with pain in the ear, dizziness, and vertigo. It is noted that some patients who report TMDs also have a history of sleep disturbances, which is noted in cone beam computed tomography (CBCT) as a reduction in the oropharyngeal airway volume. Objective To evaluate the airway volume in pre- and posttreatment of TMD with the use of neuromuscular orthotics made with ultra-low frequency transcutaneous electrical nerve stimulation (ULF-TENS). Methods A total of 15 patients were evaluated for TMDs using the related criteria. Those included were treated with ULF-TENS with evaluation of the airway volume both pre- and posttreatment using CBCT and the Dolphin 3D volume analysis software. Results While the symptoms were shown to be significantly reduced in patients who were treated with this particular modality, the airway volume varied in those who reported a reduction after a period of 3 months and those that reported after a period of 6 months. Conclusion Posttreatment evaluation of the airway should be done after a period of 6 months for a more objective evaluation. A multidisciplinary evaluation of the patient is required in such cases.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"27 4","pages":"e593-e601"},"PeriodicalIF":1.1,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4e/78/10-1055-s-0042-1758207.PMC10593537.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50157834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perivascular Innervation in the Nasal Mucosa and Clinical Findings in Patients with Allergic Rhinitis and Idiopathic Rhinitis. 变应性鼻炎和特发性鼻炎患者鼻黏膜血管周围神经支配及临床表现。

IF 1

International Archives of Otorhinolaryngology Pub Date : 2023-10-23 eCollection Date: 2023-10-01 DOI: 10.1055/s-0043-1775581

Thiago Carvalho, João Ferreira de Mello, Elia Tamaso Espin Garcia Caldini, Daniel Calduro Salgado, Nicole Mary Garcia de Carvalho, Nilsa Regina Damaceno-Rodrigues, Richard Louis Voegels

{"title":"Perivascular Innervation in the Nasal Mucosa and Clinical Findings in Patients with Allergic Rhinitis and Idiopathic Rhinitis.","authors":"Thiago Carvalho, João Ferreira de Mello, Elia Tamaso Espin Garcia Caldini, Daniel Calduro Salgado, Nicole Mary Garcia de Carvalho, Nilsa Regina Damaceno-Rodrigues, Richard Louis Voegels","doi":"10.1055/s-0043-1775581","DOIUrl":"10.1055/s-0043-1775581","url":null,"abstract":"Introduction The nonspecific hyperreactivity of rhinitis has been attributed to neurotrophins activating sensory nerves and inflammatory cells. The relationship between these markers and the intensity of the symptoms is not well established and few studies have evaluated individuals with idiopathic rhinitis. Objective The present study aims to evaluate whether perivascular innervation and nerve growth factor (NGF) are related to the intensity of the clinical conditions in allergic rhinitis (AR) and idiopathic rhinitis (IR). Methods A total of 15 patients with AR and 15 patients with IR with the indication for inferior turbinectomy (associated or not with septoplasty) were selected. The patients received a score according to their signs and symptoms. After the surgery, we quantified eosinophils, mast cells, NGF, and nerve fibers in the nasal turbinate. Results The score of the signs and symptoms was higher in the AR group. Nerve growth factor was found in the cytoplasm of inflammatory cells in the submucosa in greater quantity in the AR group. The nerve fibers were distributed throughout the tissue, mainly in the subepithelial, glandular, and vascular regions, and there was no difference between the groups. Greater perivascular innervation was associated with a higher signs and symptoms score. Conclusions We concluded that these findings suggest that the NGF produced by submucosal inflammatory cells stimulates increased perivascular innervation in rhinitis, thus directly reflecting in more intense clinical conditions, especially in AR.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"27 4","pages":"e723-e732"},"PeriodicalIF":1.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cc/b0/10-1055-s-0043-1775581.PMC10593529.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50157852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IAO Systematic Review Award 2023. 2023年国际民航组织系统评审奖。

IF 1.1

International Archives of Otorhinolaryngology Pub Date : 2023-10-23 eCollection Date: 2023-10-01 DOI: 10.1055/s-0043-1775998

Geraldo Pereira Jotz, Aline Gomes Bittencourt, Adilson Marcos Montefusco

引用次数: 0

Influence of Breathing Modes and Facial Growth Patterns on Electromyographic Fatigue of Masticatory Muscles in Children. 呼吸方式和面部生长方式对儿童咀嚼肌肌电图疲劳的影响。

IF 1.1

International Archives of Otorhinolaryngology Pub Date : 2023-10-23 eCollection Date: 2023-10-01 DOI: 10.1055/s-0042-1759606

Yulieth Paulina Stave Gomez, Nathalisa de Morais Rockenbach, Anaelena Bragança de Moraes, Eliane Castilhos Corrêa, Ana Maria Toniolo da Silva, Angela Ruviaro Busanello-Stella

{"title":"Influence of Breathing Modes and Facial Growth Patterns on Electromyographic Fatigue of Masticatory Muscles in Children.","authors":"Yulieth Paulina Stave Gomez, Nathalisa de Morais Rockenbach, Anaelena Bragança de Moraes, Eliane Castilhos Corrêa, Ana Maria Toniolo da Silva, Angela Ruviaro Busanello-Stella","doi":"10.1055/s-0042-1759606","DOIUrl":"10.1055/s-0042-1759606","url":null,"abstract":"Introduction Changes in breathing patterns affect the harmonious development of the structures of the craniofacial system, leading to changes in posture, occlusion, and facial growth patterns. However, little is known about how these changes influence the muscle contraction patterns, either at rest or while functioning, and either in a normal or unbalanced condition. Objective To study the masseter and anterior temporal muscles fatigue during mastication in nasal- and mouth-breathing children, also considering their facial growth patterns. Methods: A total of 70 children aged 6 to 12 years old who met the study criteria were assessed. Speech-language-hearing, otorhinolaryngologic, and cephalometric assessments were performed to divide them into groups. In the electromyographic assessment, the children were asked to chew gum following a metronome until they felt fatigued. The median frequency of the muscles was analyzed at 15, 30, 45, and 60 seconds of mastication. The reported time of fatigue perception was recorded. The data were analyzed with analysis of variance (ANOVA) and the Kruskal-Wallis and the Mann-Whitney U tests. Results There were no median frequency decrease patterns nor differences in the myoelectric manifestations and reported time of fatigue between the groups. Conclusion The masticatory muscles did not reveal fatigue in the electromyographic analysis; however, the fatigue time was reported, despite the absence of physiological fatigue. The breathing mode, the facial growth pattern, and the association between them did not interfere with the behavior of the median frequency of the electromyographic signal and the fatigue time perception.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"27 4","pages":"e672-e679"},"PeriodicalIF":1.1,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9a/c2/10-1055-s-0042-1759606.PMC10593541.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50157846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

International Archives of Otorhinolaryngology Celebrates Achievement of Its First Impact Factor in JCR. 国际耳鼻喉科档案庆祝其在JCR中的第一个影响因子的成就。

IF 1.1

International Archives of Otorhinolaryngology Pub Date : 2023-10-23 eCollection Date: 2023-10-01 DOI: 10.1055/s-0043-1776108

Geraldo Pereira Jotz, Adilson Marcos Montefusco

引用次数: 0

Long-term Recovery Patterns of Olfactory Function after Trans-sphenoidal Approach with Nasoseptal Flap Elevation. 鼻中隔瓣抬高经蝶窦入路后嗅觉功能的长期恢复模式。

IF 1.1

International Archives of Otorhinolaryngology Pub Date : 2023-10-23 eCollection Date: 2023-10-01 DOI: 10.1055/s-0043-1761168

Bon Min Koo, Jong In Jeong

{"title":"Long-term Recovery Patterns of Olfactory Function after Trans-sphenoidal Approach with Nasoseptal Flap Elevation.","authors":"Bon Min Koo, Jong In Jeong","doi":"10.1055/s-0043-1761168","DOIUrl":"10.1055/s-0043-1761168","url":null,"abstract":"Introduction Nasoseptal flap is widely used in reconstruction of the skull base to prevent cerebrospinal fluid leakage after surgery for skull base lesions. There has been a debate on whether more severe olfactory dysfunction occurs after nasoseptal flap elevation than the conventional trans-sphenoidal approach. Objective To compare the long-term recovery patterns associated with nasoseptal flap and the conventional trans-sphenoidal approach. Methods The subjects were divided into the conventional trans-sphenoidal approach group and the nasoseptal flap elevation group. We followed up self-reported olfactory score using the visual analogue scale and threshold discrimination identification (TDI) score of the Korean Version of the Sniffin Stick test II for 12 months, with olfactory training. Results The study included 31 patients who underwent the trans-sphenoidal approach. Compared with preoperative status, the mean visual analogue scale and TDI scores in the conventional trans-sphenoidal approach group recovered 2 months postoperatively, while in the nasoseptal flap elevation group the visual analogue scale and TDI scores recovered 6 months and 3 months after surgery, respectively. Twelve months after surgery, the visual analogue scale and TDI scores in the conventional trans-sphenoidal approach group were 9.3 ± 0.5 and 28.5 ± 4.3, while those from the nasoseptal flap elevation group were 8.9 ± 1.5 and 27.2 ± 4.7 ( p = 0.326; 0.473). Only one of the patients in the nasoseptal flap elevation group had permanent olfactory dysfunction. Conclusion The olfactory function recovered more gradually in the nasoseptal flap elevation group than in the conventional trans-sphenoidal approach group, but there was no difference between the two groups after 6 months.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"27 4","pages":"e699-e705"},"PeriodicalIF":1.1,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d8/91/10-1055-s-0043-1761168.PMC10593539.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50157848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation of Tinnitus Severity Index and Tinnitus Handicap Inventory with Hematological Parameters in Patients with Subjective Tinnitus. 主观性耳鸣患者耳鸣严重程度指数、耳鸣障碍量表与血液学参数的相关性研究。

IF 1.1

International Archives of Otorhinolaryngology Pub Date : 2023-10-23 eCollection Date: 2023-10-01 DOI: 10.1055/s-0042-1758216

Demet Yazici, Mehmet Celalettin Cihan

{"title":"Correlation of Tinnitus Severity Index and Tinnitus Handicap Inventory with Hematological Parameters in Patients with Subjective Tinnitus.","authors":"Demet Yazici, Mehmet Celalettin Cihan","doi":"10.1055/s-0042-1758216","DOIUrl":"10.1055/s-0042-1758216","url":null,"abstract":"Introduction Tinnitus etiopathogenesis is still unclear and treatment options are controversial despite current advances in medicine. Objectives To analyze the correlation between patients' symptom scores, systemic inflammation, and trombosis biomarkers. Methods In this prospective study, we evaluated the degree of complaints of subjective tinnitus patients with the tinnitus severity index (TSI) and tinnitus handicap inventory (THI), and correlated these symptom scores with hematological parameters such as the neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), mean thrombocyte volume (MPV), and platelet distribution width (PDW). Results A total of 44 patients with subjective tinnitus, 25 (56.8%) men and 19 (43.2%) women, were included in this study. The mean age of the patients was 42.3 ± 14.8 years. When the correlation between TSI and NLR, PLR, PDW, and MPV values of the patients were analyzed, no statistically significant correlation was found between TSI, NLR, and PLR ( p > 0.05). However, there was a statistically weak positive correlation between TSI, MPV, and PDW.( p < 0.05). When the correlation between THI and NLR, PLR, PDW, and MPV values of the patients were analyzed, no statistically significant correlation was found between THI, NLR, and PLR ( p > 0.05). There was a statistically weak positive correlation between THI, MPV, and PDW ( p < 0.05). Conclusion We were unable to detect any relationship between systemic inflammation markers (NLR and PLR) and symptom scores, but a weakly positive correlation was observed between thrombosis markers (MPV and PDW) and symptom scores, and as the subclinical thrombosis markers elevated, so did the symptom scores.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"27 4","pages":"e608-e612"},"PeriodicalIF":1.1,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cc/3a/10-1055-s-0042-1758216.PMC10593538.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50157836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Verbal Working Memory and Phonemic Analysis Skills in Adolescents with Cochlear Implant. 植入人工耳蜗的青少年言语工作记忆和音位分析能力的评价。

IF 1.1

International Archives of Otorhinolaryngology Pub Date : 2023-10-23 eCollection Date: 2023-10-01 DOI: 10.1055/s-0043-1761172

Nuriye Yildirim Gökay, Güzide Atalik, Şadiye Bacik Trank, Hakan Tutar, Recep Karamert, Bülent Gündüz

{"title":"Evaluation of Verbal Working Memory and Phonemic Analysis Skills in Adolescents with Cochlear Implant.","authors":"Nuriye Yildirim Gökay, Güzide Atalik, Şadiye Bacik Trank, Hakan Tutar, Recep Karamert, Bülent Gündüz","doi":"10.1055/s-0043-1761172","DOIUrl":"10.1055/s-0043-1761172","url":null,"abstract":"Introduction Adolescents with cochlear implants may have difficulty developing language and memory abilities. Objective The primary objectives of this study are (1) to evaluate the language skills and verbal working memory performance of early and late diagnosed-intervened cochlear implanted adolescents and (2) to investigate the relationship between the verbal working memory and phonemic analysis skills in adolescents with cochlear implant. Methods This study included 72 participants with cochlear implant aged between 10 and 18 years. The participants were divided into two groups; those who had first hearing aid at the age of 6 months at the latest and had a first cochlear implant in at least one ear at the latest at 24 months were included in the early group, all the others were in the late group. The phonemic analysis test, a subtest of the test of language development: Primary, 4th edition (TOLD: P-4) - Turkish version, was used to assess language-based abilities, and the meaningless word repetition (MWR) test was utilized to assess verbal working memory. Results The adolescents with cochlear implants who received early diagnosis and intervention performed statistically significantly better in phonemic analysis scores and verbal working memory tests ( p < 0.001). A statistically significant relationship was found between phonemic analysis and verbal working memory skills (Pearson, r = 0.567 and r = 0.659, p < 0.001). Conclusions Rehabilitation of phonological skills can contribute to the development of verbal working memory in adolescents with cochlear implants. There is a need for further studies on this issue with more detailed tests.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"27 4","pages":"e662-e666"},"PeriodicalIF":1.1,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/73/18/10-1055-s-0043-1761172.PMC10593525.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50157840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinicopathological Features of Buccal Squamous Cell Carcinoma with Focus on Patients Who Never Smoke and Never Drink. 口腔鳞状细胞癌的临床病理特征，以从不吸烟和不喝酒的患者为中心。

IF 1.1

International Archives of Otorhinolaryngology Pub Date : 2023-10-23 eCollection Date: 2023-10-01 DOI: 10.1055/s-0042-1755433

Yoshiyuki Iida, Shinichi Okada, Yuki Irifune, Seiya Goto, Kotaro Ishida, Fuyuki Sato, Takashi Yurikusa, Koiku Asakura, Ayaka Tsuzuki, Takashi Mukaigawa

{"title":"Clinicopathological Features of Buccal Squamous Cell Carcinoma with Focus on Patients Who Never Smoke and Never Drink.","authors":"Yoshiyuki Iida, Shinichi Okada, Yuki Irifune, Seiya Goto, Kotaro Ishida, Fuyuki Sato, Takashi Yurikusa, Koiku Asakura, Ayaka Tsuzuki, Takashi Mukaigawa","doi":"10.1055/s-0042-1755433","DOIUrl":"10.1055/s-0042-1755433","url":null,"abstract":"Introduction Oral carcinoma has been reported at a substantial proportion in patients who never smoke and never drink. However, the proportion may vary by subsite and ethnicity. Objective We aimed to determine the clinicopathological features of buccal squamous cell carcinoma (SCC) in a Japanese population. Methods We retrospectively analyzed the records of patients diagnosed with buccal SCC at our institution from September 2002 to November 2015. We reviewed the gender, age, tumor status, treatment, smoking, alcohol drinking, multiple primary cancers, and prognosis of the patients. The overall and cause-specific survival rates were calculated, and the effects of clinicopathological variables were assessed by univariate analysis. Furthermore, the cause of death was evaluated. Results Among the 63 patients (men: 38; women: 25) included in the present study, 29 (46.0%) never smoked or drank. Women were almost 5 years older than men ( p = 0.014). The number of women in the group who never smoked or drank was disproportionately higher than that of those in the smoker or drinker groups ( p < 0.001). In total, 29 patients (46.0%) had 59 multiple primary cancers, including 26 oral cancers. Surgeries and radiotherapy were performed in 57 (90.5%) and 6 (9.5%) cases, respectively. The 5-year overall survival and disease-specific survival rates were 74.6 and 78.8%, respectively. Conclusion Our study confirms that buccal SCC may develop in older adult Japanese patients, especially in women who have never smoked or drank. These patients could be at risk for second primary malignancy.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"27 4","pages":"e551-e558"},"PeriodicalIF":1.1,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/16/6d/10-1055-s-0042-1755433.PMC10593528.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50157831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Survival Outcomes and Patterns of Failure in Maxillary Alveolus Squamous Cell Carcinoma. 上颌牙槽鳞状细胞癌的生存结局和失败模式。

IF 1.1

International Archives of Otorhinolaryngology Pub Date : 2023-10-23 eCollection Date: 2023-10-01 DOI: 10.1055/s-0042-1758214

Muhammad Umar Qayyum, Ahmed Ali Keerio, Muhammad Faisal, Asma Rashid, Raza Hussain, Arif Jamshed

{"title":"Survival Outcomes and Patterns of Failure in Maxillary Alveolus Squamous Cell Carcinoma.","authors":"Muhammad Umar Qayyum, Ahmed Ali Keerio, Muhammad Faisal, Asma Rashid, Raza Hussain, Arif Jamshed","doi":"10.1055/s-0042-1758214","DOIUrl":"10.1055/s-0042-1758214","url":null,"abstract":"Introduction Squamous cell carcinoma (SCC) of the maxillary alveolus is a relatively rare disease. There is lack of data on this subsite as compared with other sites. The factors that affect survival in cases of maxillary alveolar SCC are tumor stage, local and cervical metastases, histological grading, and the margin status. Objectives To evaluate the overall survival (OS), the disease free survival (DFS), and the complex interaction and effects of margin status, histological differentiation, habits (such as smoking and the use of smokeless tobacco products), and cervical and distant metastases based on clinicopathological data. Methods We examined the electronic database at our hospital from 2003 to 2017. We included all cases with a histopathological diagnosis of SCC of the maxillary alveolus. Tumors originating primarily from the maxillary alveolus were included, while those originating from adjacent subsites, like the hard palate, the buccal mucosa or the maxillary sinus were excluded. We also excluded all the patients who were not operated on with a curative intent. Results More than half of the patients had stage-IV tumors at the time of presentation, while only one fourth of them had nodal metastasis. The rate of recurrence increased in cases of primary tumors in advanced stages and the degree of histological differentiation. The 2-year and 5-year OS rates were of 54.5% (18 patients) and 30.3% (10 patients) respectively. Conclusion Primary tumors in advanced stages, histological grade, and presence of nodal metastasis are poor prognostic markers in terms of long-term survival.","PeriodicalId":13731,"journal":{"name":"International Archives of Otorhinolaryngology","volume":"27 4","pages":"e559-e564"},"PeriodicalIF":1.1,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/91/2d/10-1055-s-0042-1758214.PMC10593516.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50157855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0