Infectious diseases now最新文献_第3页

Prevention of aspiration pneumonia recurrences 预防吸入性肺炎复发

IF 2.9 4区医学

Infectious diseases now Pub Date : 2025-06-09 DOI: 10.1016/j.idnow.2025.105102

Thibaut Fraisse , V. Prendki , A. Putot , C. Garcia-Carmona , M. Perrin , N. Chebib , C. Andrejak , M. Matta , G. Gavazzi , Y. Rolland , S. Diamantis

{"title":"Prevention of aspiration pneumonia recurrences","authors":"Thibaut Fraisse , V. Prendki , A. Putot , C. Garcia-Carmona , M. Perrin , N. Chebib , C. Andrejak , M. Matta , G. Gavazzi , Y. Rolland , S. Diamantis","doi":"10.1016/j.idnow.2025.105102","DOIUrl":"10.1016/j.idnow.2025.105102","url":null,"abstract":"<div><h3>Context</h3><div>Aspiration pneumonia occurs after a documented aspiration or in patients with aspiration risk factors, suggesting a potential oropharyngeal portal of entry for the responsible pathogens. Strategies aimed at preventing recurrences are based on the identification of risk factors, their modification, and the implementation of appropriate corrective measures.</div></div><div><h3>Methods</h3><div>A comprehensive review of the literature (2000–2025) on the prevention of aspiration pneumonia was conducted.</div></div><div><h3>Results</h3><div>Treatments likely to exacerbate swallowing disorders must be reassessed, particularly anticholinergics, sedatives, and psychotropic drugs. No treatment was significantly effective in directly preventing aspiration pneumonia. Nutritional requirements are met using enteral nutrition, but it increases oral bacterial colonization, oral biofilm thickness, and muscle weakness. A series of measures (semi-sitting positioning in patients with impaired awareness or enteral nutrition, speech therapy, rehabilitation, and elimination of dental biofilm) were significantly effective in preventing aspiration pneumonia. Adapting food texture and thickening liquids are measures being considered to reduce the risks, despite the potential impact on the quality of life and on nutritional intake.</div></div><div><h3>Conclusion</h3><div>A multidisciplinary assessment is recommended after an episode of pneumonia in the elderly to identify the pathogen’s route of entry and to establish a plan to prevent recurrences. Future research will need to determine priorities among the various measures proposed to optimize management strategies.</div></div>","PeriodicalId":13539,"journal":{"name":"Infectious diseases now","volume":"55 6","pages":"Article 105102"},"PeriodicalIF":2.9,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144263181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CV2 : Editorial board 编辑委员会

IF 2.9 4区医学

Infectious diseases now Pub Date : 2025-05-28 DOI: 10.1016/S2666-9919(25)00074-0

引用次数: 0

The role of high-sensitivity C-reaction protein in the prediction of long-term mortality in people living with HIV: Results from the IDEA-TB cohort study in Kenya 高灵敏度c反应蛋白在预测HIV感染者长期死亡率中的作用：来自肯尼亚IDEA-TB队列研究的结果

IF 2.9 4区医学

Infectious diseases now Pub Date : 2025-05-20 DOI: 10.1016/j.idnow.2025.105100

Fausto Ciccacci , Benjamin Welu , Harrison Ndoi , Irene Karea , Anna Maria Doro Altan , Davide Brambilla , Kenneth Munene , Brenda Opanga , Aiban Ronoh , Scolastica Mukwanjagi , Raymond Mwiraria , Giovanni Guidotti , Stefano Orlando

引用次数: 0

Cirrhotic patients with bone and joint infections: A 10-year cohort study from a reference center 肝硬化合并骨关节感染患者：来自参考中心的10年队列研究

IF 2.9 4区医学

Infectious diseases now Pub Date : 2025-05-20 DOI: 10.1016/j.idnow.2025.105099

V. Tuloup , C. Doumit , M.F. Lartigue , L.R. Le Nail , M. Lacasse , A. Lemaignen , among the Tours CRIOAC centre

{"title":"Cirrhotic patients with bone and joint infections: A 10-year cohort study from a reference center","authors":"V. Tuloup , C. Doumit , M.F. Lartigue , L.R. Le Nail , M. Lacasse , A. Lemaignen , among the Tours CRIOAC centre","doi":"10.1016/j.idnow.2025.105099","DOIUrl":"10.1016/j.idnow.2025.105099","url":null,"abstract":"<div><h3>Introduction</h3><div>Bone and joint infections (BJI) require long-term and frequently high-dose antimicrobial treatment, often with heightened risk of drug-drug or drug-disease interactions. However, in some cases, notably regarding cirrhotic patients, these infections have yet to be adequately described. Cirrhosis is a major cause of end-stage chronic liver disease, entailing massive disorders in hepatic metabolism and a high rate of infections and comorbidities. We aimed to characterize the cirrhosis − BJI population treated over the last 10 years in our reference centre.</div></div><div><h3>Material and methods</h3><div>A descriptive monocentric retrospective study analysed routine care data extracted from our computer files. Patients labelled with a chronic hepatic disease were included. Biological, clinical and survival rate were researched. Drug-drug and drug-disease interactions were compiled and analysed using the exposure ratio, according to the Child-Pugh scale.</div></div><div><h3>Results</h3><div>Eighteen patients were included, for 28 presentations. Twelve were Child-Pugh B or C. Only two out of the 18 patients had their antimicrobial dosage adjusted. No patient who had not received the recommended dose adjustment was admitted to the emergency department or for consultation for an antibiotic-related adverse event. During the 1st year, two patients (11.1 %) required hospitalization for revision surgery. Neither relapsed a second time. Six patients (33.3 %) died during follow-up, but none of the deaths were related to infection (four cancers, two ischemic events).</div></div><div><h3>Conclusion</h3><div>We have shown that cirrhotic patients with BJI are infected with the same pathogens as the general population. Dose adjustments remain unclear, and further studies are required. BJI infections are particularly complex, and require enhanced multidisciplinary management.</div></div>","PeriodicalId":13539,"journal":{"name":"Infectious diseases now","volume":"55 6","pages":"Article 105099"},"PeriodicalIF":2.9,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144108080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quality of the antibiotic advice provided by referral centres in France: a prospective audit 法国转诊中心提供的抗生素咨询的质量：前瞻性审计。

IF 2.9 4区医学

Infectious diseases now Pub Date : 2025-05-17 DOI: 10.1016/j.idnow.2025.105089

Pierre-Marie Roger , Nicolas Lesaffre , Timothé Thiel , Assi Assi , Eric Denes

{"title":"Quality of the antibiotic advice provided by referral centres in France: a prospective audit","authors":"Pierre-Marie Roger , Nicolas Lesaffre , Timothé Thiel , Assi Assi , Eric Denes","doi":"10.1016/j.idnow.2025.105089","DOIUrl":"10.1016/j.idnow.2025.105089","url":null,"abstract":"<div><h3>Objectives</h3><div>Our aim was to determine the quality of antibiotic advice given by antibiotic referral centres (RC) to general practitioners (GP).</div></div><div><h3>Method</h3><div>A prospective multicentre audit of antibiotic advice on four urinary tract infections (UTI) and four respiratory infections delivered to GPs by RCs was carried out from May to August 2024. Recommendations were put forward by three senior infectious disease specialists in accordance with the existing guidelines.</div></div><div><h3>Results</h3><div>Fourteen RCs were asked to provide 112 recommendations, and 106 responses were obtained (95 %). Advice was given by a senior physician in 76 cases (72 %) and a resident in the 30 others (38 %). The mean score/5 [± std deviation] <em>per</em> clinical case was 2.7 ± 1.9, with a difference between UTI and respiratory infections: 3.5 ± 1.7 versus 3.0 ± 1.1, p = 0.043, and a higher score for senior physicians as compared to residents: 2.9 ± 1.8 versus 2.0 ± 1.9, p = 0.019.</div></div><div><h3>Conclusion</h3><div>The quality of antibiotic-related advice provided by RCs to GPs appeared heterogeneous, and improvement could be facilitated by favouring senior physician intervention.</div></div>","PeriodicalId":13539,"journal":{"name":"Infectious diseases now","volume":"55 5","pages":"Article 105089"},"PeriodicalIF":2.9,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In vitro susceptibility of aztreonam/avibactam against metallo-β-Lactamase-producing Enterobacterales in a Croatian tertiary care hospital 克罗地亚一家三级医院氨曲南/阿维巴坦对产金属β-内酰胺酶肠杆菌的体外敏感性研究

IF 2.9 4区医学

Infectious diseases now Pub Date : 2025-05-17 DOI: 10.1016/j.idnow.2025.105092

Ivana Majdandžić , Ivana Mareković , Ana Budimir

引用次数: 0

Bictegravir use during pregnancy 怀孕期间使用比替格拉韦。

IF 2.9 4区医学

Infectious diseases now Pub Date : 2025-05-17 DOI: 10.1016/j.idnow.2025.105093

Emmanuel Mortier , Margaux Froidefond , Roger Serhal , Christine Chan Chee , Sarah Permal , Mohamadou Niang

引用次数: 0

Adapting pneumococcal conjugate vaccines to serotype replacement: are we always one step behind? 使肺炎球菌结合疫苗适应血清型替代：我们是否总是落后一步？

IF 2.9 4区医学

Infectious diseases now Pub Date : 2025-05-13 DOI: 10.1016/j.idnow.2025.105085

Zein Assad , Nathanaël Hozé , Thibaut Morel-Journel , Naïm Ouldali

引用次数: 0

Response to Liu, Yuan, and Fu regarding their letter ‘Optimizing the research value and clinical utility of suPAR in COVID-19 回复刘、袁、傅关于优化suPAR在COVID-19中的研究价值和临床应用的信函

IF 2.9 4区医学

Infectious diseases now Pub Date : 2025-05-10 DOI: 10.1016/j.idnow.2025.105086

Pauline Nègre , Didier Tayac , Thibaut Jamme , Marie-Sophie Combis , Françoise Maupas-Schwalm

引用次数: 0

Optimizing the research value and clinical utility of suPAR in COVID-19 优化suPAR在COVID-19中的研究价值和临床应用

IF 2.9 4区医学

Infectious diseases now Pub Date : 2025-05-08 DOI: 10.1016/j.idnow.2025.105083

Hai-Feng Liu , Ting-Yun Yuan , Hong-Min Fu

引用次数: 0