发布求助
文献互助 智能选刊 最新文献

Hypertension in Pregnancy最新文献

筛选
英文 中文
Use of FMF algorithm for prediction of preeclampsia in high risk pregnancies: a single center longitudinal study. 使用FMF算法预测高危妊娠子痫前期:单中心纵向研究
IF 1.5 4区 医学
Hypertension in Pregnancy Pub Date : 2021-08-01 Epub Date: 2021-05-12 DOI: 10.1080/10641955.2021.1921791
Petar Cabunac, Nataša Karadžov Orlić, Daniela Ardalić, Barbara Damnjanović Pažin, Srđan Stanimirović, Gorica Banjac, Aleksandra Stefanović, Vesna Spasojević-Kalimanovska, Amira Egić, Nina Rajović, Nataša Milić, Željko Miković
{"title":"Use of FMF algorithm for prediction of preeclampsia in high risk pregnancies: a single center longitudinal study.","authors":"Petar Cabunac,&nbsp;Nataša Karadžov Orlić,&nbsp;Daniela Ardalić,&nbsp;Barbara Damnjanović Pažin,&nbsp;Srđan Stanimirović,&nbsp;Gorica Banjac,&nbsp;Aleksandra Stefanović,&nbsp;Vesna Spasojević-Kalimanovska,&nbsp;Amira Egić,&nbsp;Nina Rajović,&nbsp;Nataša Milić,&nbsp;Željko Miković","doi":"10.1080/10641955.2021.1921791","DOIUrl":"https://doi.org/10.1080/10641955.2021.1921791","url":null,"abstract":"<p><p><b>OBJECTIVE</b>: This study aimed to assess the accuracy of The Fetal Medicine Foundation (FMF) screening algorithm for the prediction of preeclampsia.<b>METHODS</b>: Out of 138 women with high-risk pregnancies prospectively followed, 30 developed preeclampsia. The clinical examination and biochemical measurements were performed at first, second, early and late third trimester.<b>RESULTS</b>: A lower PAPP-A levels were found in the first trimester, while sFlt/PlGF was increased in the second and early third trimester in preeclampsia (p>0.05). FMF algorithm presented higher specificity (>70%), but had a drawback of lower sensitivity (35-77%).<b>CONCLUSION</b>: FMF algorithm had modest performance in the prediction of preeclampsia for high-risk pregnancies.</p>","PeriodicalId":13054,"journal":{"name":"Hypertension in Pregnancy","volume":"40 3","pages":"171-179"},"PeriodicalIF":1.5,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10641955.2021.1921791","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38974167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Increased expression of lncRNA SNHG7 promotes the cell viability, migration, and invasion in pre-eclampsia via modulating the miR-214-5p/TWIST1 axis. lncRNA SNHG7的表达增加通过调节miR-214-5p/TWIST1轴促进子痫前期细胞的活力、迁移和侵袭。
IF 1.5 4区 医学
Hypertension in Pregnancy Pub Date : 2021-08-01 Epub Date: 2021-10-04 DOI: 10.1080/10641955.2021.1981372
Yongping Wang, Zhihui Zhang
{"title":"Increased expression of lncRNA SNHG7 promotes the cell viability, migration, and invasion in pre-eclampsia via modulating the miR-214-5p/TWIST1 axis.","authors":"Yongping Wang,&nbsp;Zhihui Zhang","doi":"10.1080/10641955.2021.1981372","DOIUrl":"https://doi.org/10.1080/10641955.2021.1981372","url":null,"abstract":"<p><strong>Purpose: </strong>This study is aimed to elucidate the molecular mechanism of lncRNA SNHG7 on pre-eclampsia (PE).</p><p><strong>Methods: </strong>The expression of SNHG7, miR-214-5p and TWIST1 in PE placental tissues was detected by qRT-PCR. The regulatory mechanism of SNHG7/miR-214-5p/TWIST1 axis on PE was determined using MTT, wound healing, transwell invasion, and western blot assays.</p><p><strong>Results: </strong>In PE pregnancies, SNHG7 and TWIST1 were decreased, while miR-214-5p was increased.The elevated miR-214-5p and decreased TWIST1 partly eliminated the promoting effects of SNHG7 up-regulation on the viability and metastasis of JEG-3 cells.</p><p><strong>Conclusions: </strong>Up-regulated SNHG7 protects against PE through modulating the miR-214-5p/TWIST1 axi.</p>","PeriodicalId":13054,"journal":{"name":"Hypertension in Pregnancy","volume":"40 3","pages":"261-270"},"PeriodicalIF":1.5,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39483563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Down-regulated placental miR-21 contributes to preeclampsia through targeting RASA1. 胎盘miR-21下调通过靶向RASA1参与子痫前期。
IF 1.5 4区 医学
Hypertension in Pregnancy Pub Date : 2021-08-01 Epub Date: 2021-08-31 DOI: 10.1080/10641955.2021.1974031
Kun Dong, Ying Hou, Na Zhang, Bide Duan, Airong Ma, Zhiwei Zhang
{"title":"Down-regulated placental miR-21 contributes to preeclampsia through targeting RASA1.","authors":"Kun Dong,&nbsp;Ying Hou,&nbsp;Na Zhang,&nbsp;Bide Duan,&nbsp;Airong Ma,&nbsp;Zhiwei Zhang","doi":"10.1080/10641955.2021.1974031","DOIUrl":"https://doi.org/10.1080/10641955.2021.1974031","url":null,"abstract":"<p><p>Human placenta was obtained from early onset preeclampsia, late onset preeclampsia, and their gestational age-matched normal pregnancy. Using RT-qPCR, western blot, and immunohistochemistry, it was demonstrated that miR-21 expressions were significantly decreased in preeclampsia while RASA1 were increased. Suppression of miR-21 in placental HTR-8/SVneo cells, remarkably upregulated RASA1, decreased proliferation, inhibited invasion, and promoted apoptosis of trophoblast cells, while overexpression of miR-21 alleviated these effects. Dual-luciferase reporter assays revealed RASA1 to be a direct target of miR-21 in trophoblast cells. miR-21 may serve key roles in the development of preeclampsia by targeting RASA1.</p>","PeriodicalId":13054,"journal":{"name":"Hypertension in Pregnancy","volume":"40 3","pages":"236-245"},"PeriodicalIF":1.5,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39372674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Serum survivin is decreased in women with preeclampsia. 子痫前期妇女血清生存素降低。
IF 1.5 4区 医学
Hypertension in Pregnancy Pub Date : 2021-05-01 Epub Date: 2021-05-20 DOI: 10.1080/10641955.2021.1917601
Onur Güralp, Koray Gök, Nevin Tüten, Kübra Hamzaoglu, Melike Makul, Yahya Ozgun Oner, Huri Bulut, Meike Schild-Suhren, Eduard Malik, Abdullah Tüten
{"title":"Serum survivin is decreased in women with preeclampsia.","authors":"Onur Güralp,&nbsp;Koray Gök,&nbsp;Nevin Tüten,&nbsp;Kübra Hamzaoglu,&nbsp;Melike Makul,&nbsp;Yahya Ozgun Oner,&nbsp;Huri Bulut,&nbsp;Meike Schild-Suhren,&nbsp;Eduard Malik,&nbsp;Abdullah Tüten","doi":"10.1080/10641955.2021.1917601","DOIUrl":"https://doi.org/10.1080/10641955.2021.1917601","url":null,"abstract":"<p><p><b>Objective</b>: To evaluate the serum survivin level in preeclampsia.<b>Methods</b>: Eighty-eight pregnancies complicated with preeclampsia and 88 gestational-age (GA)-matched uncomplicated pregnancies were evaluated.<b>Results</b>: Mean serum survivin was detected to be significantly decreased in the early- (EOPE) and late-onset (LOPE) preeclampsia subgroups than the GA-matched control-groups; and were comparable in EOPE- and LOPE-groups after correction for GA. Serum survivin had weak negative correlations with systolic and diastolic arterial blood pressure.<b>Conclusion</b>: The serum survivin level was decreased in preeclamptic patients than the GA-matched controls. More comprehensive studies are needed to clarify the timing and extent of placental apoptosis in preeclampsia.</p>","PeriodicalId":13054,"journal":{"name":"Hypertension in Pregnancy","volume":"40 2","pages":"144-151"},"PeriodicalIF":1.5,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10641955.2021.1917601","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39000748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Household food insecurity associations with pregnancy hypertension, diabetes mellitus and infant birth anthropometric measures: a cross-sectional study of Iranian mothers. 家庭粮食不安全与妊娠高血压、糖尿病和婴儿出生人体测量测量的关系:对伊朗母亲的横断面研究。
IF 1.5 4区 医学
Hypertension in Pregnancy Pub Date : 2021-05-01 Epub Date: 2021-01-21 DOI: 10.1080/10641955.2021.1874010
Elham Hojaji, Mobina Aghajani, Rosa Zavoshy, Mostafa Noroozi, Hassan Jahanihashemi, Neda Ezzeddin
{"title":"Household food insecurity associations with pregnancy hypertension, diabetes mellitus and infant birth anthropometric measures: a cross-sectional study of Iranian mothers.","authors":"Elham Hojaji,&nbsp;Mobina Aghajani,&nbsp;Rosa Zavoshy,&nbsp;Mostafa Noroozi,&nbsp;Hassan Jahanihashemi,&nbsp;Neda Ezzeddin","doi":"10.1080/10641955.2021.1874010","DOIUrl":"https://doi.org/10.1080/10641955.2021.1874010","url":null,"abstract":"<p><p><b>Objective</b>: The purpose of this study was to determine the associations between food insecurity on pregnancy and its outcomes.<b>Materials and methods</b>: This cross-sectional study was carried out on 700 Iranian mothers. Household socioeconomic status, prenatal information and household food security status <b>were assessed using questionnaires. Data analysis was applied by SPSS version 22.</b><b>Results</b>: The results of the study showed a significant association between food insecurity with gestational diabetes mellitus. The results also showed a significant association between birth weight, and height with pregnancy-induced hypertension.<b>Conclusion</b>: food insecure women should be recognized, and receive appropriate training and assistance.</p>","PeriodicalId":13054,"journal":{"name":"Hypertension in Pregnancy","volume":"40 2","pages":"109-117"},"PeriodicalIF":1.5,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10641955.2021.1874010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38764948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Monocytes from preeclamptic women previously treated with silibinin attenuate oxidative stress in human endothelial cells. 先前用水飞蓟宾治疗的子痫前期妇女的单核细胞减弱了人内皮细胞的氧化应激。
IF 1.5 4区 医学
Hypertension in Pregnancy Pub Date : 2021-05-01 Epub Date: 2021-02-14 DOI: 10.1080/10641955.2021.1884258
Virgínia Juliani Gomes, Priscila Rezeck Nunes, Sarah McCann Haworth, Valéria Cristina Sandrim, José Carlos Peraçoli, Maria Terezinha S Peraçoli, Mattias Carlström
{"title":"Monocytes from preeclamptic women previously treated with silibinin attenuate oxidative stress in human endothelial cells.","authors":"Virgínia Juliani Gomes,&nbsp;Priscila Rezeck Nunes,&nbsp;Sarah McCann Haworth,&nbsp;Valéria Cristina Sandrim,&nbsp;José Carlos Peraçoli,&nbsp;Maria Terezinha S Peraçoli,&nbsp;Mattias Carlström","doi":"10.1080/10641955.2021.1884258","DOIUrl":"https://doi.org/10.1080/10641955.2021.1884258","url":null,"abstract":"<p><p><b>Objective:</b> To investigate whether the supernatant from monocytes of preeclamptic and normotensive pregnant women, cultured in vitro with silibinin, can modulate oxidative stress in HUVEC.<b>Methods</b>: Concentrations of IL-1β, IL-10, and TNF-α in monocyte culture supernatants were determined by ELISA. HUVEC and their supernatant cultures were employed for determination of NO, nitrite and nitrate, lipid peroxidation, and hemeoxygenase-1 (HO-1).<b>Results</b>: HUVEC treatment with supernatant of preeclamptic monocytes cultured with silibinin produced increased levels of nitrite, reduced lipid peroxidation, and increased HO-1.<b>Conclusion</b>: Supernatant of monocytes from preeclamptic women induce oxidative stress in HUVEC which can be reduced by silibinin treatment.<b>Abbreviations:</b> DAF-FM<sup>TM</sup>, Diaminofluorescein-FM; EDTA, Ethylenediaminetetraacetic acid; HO-1, heme oxygenase-1; HPLC, high-performance liquid chromatography; HUVEC, human umbilical vein endothelial cell; MDA, malondialdehyde; NO, nitric oxide; NT, normotensive; PE, preeclampsia; ROS, reactive oxygen species; Sb, silibinin.</p>","PeriodicalId":13054,"journal":{"name":"Hypertension in Pregnancy","volume":"40 2","pages":"124-132"},"PeriodicalIF":1.5,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10641955.2021.1884258","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25368548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Prognostic role of increased serum homocysteine concentration in preeclampsia. 血清同型半胱氨酸浓度升高对子痫前期预后的影响。
IF 1.5 4区 医学
Hypertension in Pregnancy Pub Date : 2021-05-01 Epub Date: 2021-02-08 DOI: 10.1080/10641955.2021.1884257
Andrey Gaiday, Akylbek Tussupkaliyev, Saule Bermagambetova, Svetlana Sakhanova, Andrii Dinets
{"title":"Prognostic role of increased serum homocysteine concentration in preeclampsia.","authors":"Andrey Gaiday,&nbsp;Akylbek Tussupkaliyev,&nbsp;Saule Bermagambetova,&nbsp;Svetlana Sakhanova,&nbsp;Andrii Dinets","doi":"10.1080/10641955.2021.1884257","DOIUrl":"https://doi.org/10.1080/10641955.2021.1884257","url":null,"abstract":"<p><p><b>Objective:</b> To assess homocysteine (Hcy) concentration in women with preeclampsia (PE).<b>Methods:</b> Hcy concentrations were detected by ELISA in 305 pregnancies.<b>Results:</b> Hcy concentration in patients with PE was 16.07 umol/L at 10-14 weeks as compared to 7.19 umol/L in normotensive pregnancies (p < 0.0001). Optimal cutoff level for Hcy in the first trimester of pregnancy was >9.55 umol/L with area under curve of 0.859, sensitivity of 91.67%, specificity of 72.24%.<b>Conclusion:</b> Assessment of serum Hcy concentration may be used as a predictor of PE, with the highest diagnostic utility in the first trimester of pregnancy.</p>","PeriodicalId":13054,"journal":{"name":"Hypertension in Pregnancy","volume":"40 2","pages":"118-123"},"PeriodicalIF":1.5,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10641955.2021.1884257","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25342152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Letter to the Editor regarding Cunningham et al. 2020. 关于Cunningham et al. 2020的致编辑信。
IF 1.5 4区 医学
Hypertension in Pregnancy Pub Date : 2021-05-01 Epub Date: 2021-04-09 DOI: 10.1080/10641955.2021.1899201
{"title":"Letter to the Editor regarding Cunningham et al. 2020.","authors":"","doi":"10.1080/10641955.2021.1899201","DOIUrl":"https://doi.org/10.1080/10641955.2021.1899201","url":null,"abstract":"","PeriodicalId":13054,"journal":{"name":"Hypertension in Pregnancy","volume":"40 2","pages":"133"},"PeriodicalIF":1.5,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10641955.2021.1899201","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25574315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
LINC01128 - miR-16 interaction regulates the migration and invasion of human chorionic trophoblast cells. LINC01128 - miR-16相互作用调节人绒毛膜滋养细胞的迁移和侵袭。
IF 1.5 4区 医学
Hypertension in Pregnancy Pub Date : 2021-05-01 Epub Date: 2021-04-21 DOI: 10.1080/10641955.2021.1917602
Xinyuan Zhao, Fei Liu, Jin Zhang, Jianhua Zhang, Ludan Zhang, Lin Chen
{"title":"LINC01128 - miR-16 interaction regulates the migration and invasion of human chorionic trophoblast cells.","authors":"Xinyuan Zhao,&nbsp;Fei Liu,&nbsp;Jin Zhang,&nbsp;Jianhua Zhang,&nbsp;Ludan Zhang,&nbsp;Lin Chen","doi":"10.1080/10641955.2021.1917602","DOIUrl":"https://doi.org/10.1080/10641955.2021.1917602","url":null,"abstract":"<p><p><b>Objective</b>: Pre-eclampsia (PE) is a major complication of pregnancy, but its pathogenesis is unclear. This study explored the role of LINC01128 in the progression of PE, and its interaction with miR-16 on the behaviors of trophoblasts.<b>Methods</b>: The mRNA levels of LINC01128 and miR-16 in placental tissues and HTR-8/SVneo cells were analyzed by quantitative real-time polymerase chain reaction (qRT-PCR). Cell Counting Kit (CCK)-8, wound healing assay and transwell assay were used to detect proliferation, migration and invasion. E-Cadherin, Vimentin, Matrix metalloproteinase 2 (MMP2) and MMP9 protein expressions were detected by Western blot. The correlation between LINC01128 and miR-16 was determined and verified by starBase and dual-luciferase assay.<b>Results</b>: The expression of LINC01128 was downregulated in PE. Overexpression of LINC01128 promoted LINC01128 expression, cell proliferation, migration, invasion and the expressions of Vimentin, MMP2 and MMP9, but inhibited the expression of E-Cadherin. SiLINC01128 showed opposite effects. MiR-16 interacted with LINC01128, and miR-16 was high-expressed in PE placentae. MiR-16 inhibitor promoted cell proliferation, migration, invasion and related protein expressions, but inhibited the expression of E-Cadherin. However, siLINC01128 inhibited the regulatory effect of miR-16 inhibitor on HTR-8/Svneo cells.<b>Conclusion</b>: LINC01128/miR-16 is involved in HTR-8/SVneo cells by regulating the migration and invasion of human chorionic trophoblast cells.</p>","PeriodicalId":13054,"journal":{"name":"Hypertension in Pregnancy","volume":"40 2","pages":"152-161"},"PeriodicalIF":1.5,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10641955.2021.1917602","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38901579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Unraveling the role of oxidative stress and lipid status parameters in the onset of preeclampsia. 揭示氧化应激和脂质状态参数在子痫前期发病中的作用。
IF 1.5 4区 医学
Hypertension in Pregnancy Pub Date : 2021-05-01 Epub Date: 2021-05-03 DOI: 10.1080/10641955.2021.1921790
Petar Cabunac, Nataša Karadžov Orlić, Daniela Ardalić, Gorica Banjac, Jasmina Ivanišević, Jelena Janać, Jelena Vekić, Aleksandra Zeljković, Marija Mihajlović, Nina Rajović, Nataša Milić, Željko Miković
{"title":"Unraveling the role of oxidative stress and lipid status parameters in the onset of preeclampsia.","authors":"Petar Cabunac,&nbsp;Nataša Karadžov Orlić,&nbsp;Daniela Ardalić,&nbsp;Gorica Banjac,&nbsp;Jasmina Ivanišević,&nbsp;Jelena Janać,&nbsp;Jelena Vekić,&nbsp;Aleksandra Zeljković,&nbsp;Marija Mihajlović,&nbsp;Nina Rajović,&nbsp;Nataša Milić,&nbsp;Željko Miković","doi":"10.1080/10641955.2021.1921790","DOIUrl":"https://doi.org/10.1080/10641955.2021.1921790","url":null,"abstract":"<p><p><b>OBJECTIVE</b>: The aim of the study was to assess the potential role of oxidative stress and lipid status in the onset of preeclampsia.<b>METHODS</b>: 138 high-risk pregnant women were prospectively followed. Assessment of oxidative stress (TAS, TOS, AOPP and SH groups) and lipid status (t-C, LDL-C, HDL-C, TGC, APO-A1, APO-B) was carried out during the pregnancy.<b>RESULTS</b>: 30 women developed preeclampsia. TGC, atherogenic index of plasma, TAS and SH levels were higher in women who subsequently developed preeclampsia (p<0.05).<b>CONCLUSION</b>: Oxidative stress and lipid status disturbance have a potential role in the onset of preeclampsia in high risk pregnancies.</p>","PeriodicalId":13054,"journal":{"name":"Hypertension in Pregnancy","volume":"40 2","pages":"162-170"},"PeriodicalIF":1.5,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10641955.2021.1921790","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38944023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信