Hypertension in Pregnancy最新文献_第10页

Comparison of three definitions of metabolic syndrome and relation to risk of recurrent preeclampsia. 代谢综合征三种定义的比较及其与子痫前期复发风险的关系。

IF 1.5 4区医学

Hypertension in Pregnancy Pub Date : 2021-02-01 Epub Date: 2021-01-18 DOI: 10.1080/10641955.2021.1872614

Eva Stekkinger, Ralph R Scholten, Wieteke M Heidema, Marc E A Spaanderman

{"title":"Comparison of three definitions of metabolic syndrome and relation to risk of recurrent preeclampsia.","authors":"Eva Stekkinger, Ralph R Scholten, Wieteke M Heidema, Marc E A Spaanderman","doi":"10.1080/10641955.2021.1872614","DOIUrl":"https://doi.org/10.1080/10641955.2021.1872614","url":null,"abstract":"Objective. To determine the prevalence of metabolic syndrome in formerly preeclamptic women according to three definitions of metabolic syndrome (World Health Organization [WHO], International Diabetes Federation [IDF], and Third Adult Treatment Panel updated [ATPIII]), to evaluate agreement amongst definitions and to compare the risk of recurrent preeclampsia. Methods. In 197 women with a history of preeclampsia, we determined presence of metabolic syndrome using WHO, IDF, and ATPIII criteria. We evaluated agreement amongst definitions by using Kappa statistics. The prevalence of recurrent preeclampsia was compared between women with and without inter-pregnancy metabolic syndrome, according to the three definitions. Results. A total of 40 (20%), 46 (23%), and 31 (16%) of women with previous preeclampsia were classified as having metabolic syndrome postpartum according to WHO, IDF, and ATPIII criteria, respectively. Agreement among criteria was considered substantial between WHO and IDF (κ = 0.64, 95% CI 0.53-0.79), WHO and ATPIII (κ = 0.74, 95% CI 0.62-0.86), and IDF and ATPIII (κ = 0.66, 95% CI 0.51-0.77). The prevalence of recurrent preeclampsia was 45% versus 17% in women with and without inter-pregnancy metabolic syndrome according to the WHO definition (P < 0.001), 26% versus 21% according to the IDF criteria (P = 0.16), and 39% versus 20% according to the ATPIII definition (P = 0.02). Conclusions. Agreement among WHO, IDF, and ATPIII criteria of metabolic syndrome in women after preeclampsia is considered substantial. The risk of recurrent preeclampsia is almost one out of two in women with inter-pregnancy metabolic syndrome according to the WHO criteria.","PeriodicalId":13054,"journal":{"name":"Hypertension in Pregnancy","volume":"40 1","pages":"97-108"},"PeriodicalIF":1.5,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10641955.2021.1872614","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38834186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Prenatal exposure to preeclampsia as a risk factor for long-term endocrine morbidity of the offspring. 产前暴露于子痫前期是子代长期内分泌疾病的危险因素。

IF 1.5 4区医学

Hypertension in Pregnancy Pub Date : 2021-02-01 Epub Date: 2020-12-02 DOI: 10.1080/10641955.2020.1854300

Sharon Davidesko, Kira Nahum Sacks, Michael Friger, Alon Haim, Eyal Sheiner

引用次数: 5

Prehypertension in early pregnancy is a risk factor for hypertensive disorders during pregnancy: A historical cohort study in Japan. 妊娠早期高血压前期是妊娠期高血压疾病的危险因素:日本的一项历史队列研究

IF 1.5 4区医学

Hypertension in Pregnancy Pub Date : 2021-02-01 Epub Date: 2020-12-26 DOI: 10.1080/10641955.2020.1864637

Takeshi Nagao, Keisuke Saito, Michiko Yamanaka

引用次数: 3

Soluble Flt1 levels are associated with cardiac dysfunction in Black women with and without severe preeclampsia. 可溶性Flt1水平与有或无严重子痫前期黑人妇女的心功能障碍有关。

IF 1.5 4区医学

Hypertension in Pregnancy Pub Date : 2021-02-01 Epub Date: 2020-12-20 DOI: 10.1080/10641955.2020.1861462

Lisa Levine, Zolt Arany, Adina Kern-Goldberger, Nathanael Koelper, Jennifer Lewey, Mary D Sammel, Michal A Elovitz, Bonnie Ky

引用次数: 2

Role of maternal nutrition and oxidative stress in placental telomere attrition in women with preeclampsia. 母体营养和氧化应激在子痫前期妇女胎盘端粒磨损中的作用。

IF 1.5 4区医学

Hypertension in Pregnancy Pub Date : 2021-02-01 Epub Date: 2021-01-07 DOI: 10.1080/10641955.2020.1869248

Aditi A Godhamgaonkar, Deepali P Sundrani, Sadhana R Joshi

引用次数: 4

Haplotype-based, case-control study of myosin phosphatase target subunit 1 (PPP1R12A) gene and hypertensive disorders of pregnancy. 基于单倍型的肌球蛋白磷酸酶靶亚基1 (PPP1R12A)基因与妊娠高血压疾病的病例对照研究

IF 1.5 4区医学

Hypertension in Pregnancy Pub Date : 2021-02-01 Epub Date: 2021-01-18 DOI: 10.1080/10641955.2021.1872613

Ai Kono, Kaori Shinya, Tomohiro Nakayama, Elisa Shikata, Tatsuo Yamamoto, Kei Kawana

{"title":"Haplotype-based, case-control study of myosin phosphatase target subunit 1 (PPP1R12A) gene and hypertensive disorders of pregnancy.","authors":"Ai Kono, Kaori Shinya, Tomohiro Nakayama, Elisa Shikata, Tatsuo Yamamoto, Kei Kawana","doi":"10.1080/10641955.2021.1872613","DOIUrl":"https://doi.org/10.1080/10641955.2021.1872613","url":null,"abstract":"Objective: Hypertensive disorders of pregnancy (HDP) are thought to be a multifactorial genetic disease. Myosin light chain phosphorylation, which is involved in the regulation of vascular smooth muscle contraction and relaxation and thus contributes to the maintenance of blood pressure, is related to HDP. The official symbol of the gene for the production of MYPT1 protein is PPP1R12A gene. Thus, we investigated the possibility that the PPP1R12A gene is related to HDP. Methods: Subjects were 194 pregnant women with HDP and a control group of 262 pregnant women from those women examined. Four SNVs (rs7296839, rs11114256, rs2596793, and rs2694657) were selected from the PPP1R12A gene region. The HDP group was divided according to disease type, and each group was analyzed in comparison with the control group. Results: In the association analysis using the PPP1R12A gene, there were significant differences between the control group and the superimposed preeclampsia (SPE) group for rs11114256 in allele frequency distribution (P = 0.017) and genome frequency distribution in the dominant model (P = 0.014), and for rs2694657 genotype distribution frequency in the recessive model (P = 0.018). In the association analysis using haplotypes, there was a significant difference for G-A-A-G (rs7296839-rs11114256-rs2596793-rs2694657). In an analysis of haplotype-based case-control study, there was a significant difference for G-A-A-G between the control group (0.00%) and the HDP group (2.46%) (P = 0.038). Furthermore, the G-T-A-G haplotype was significantly higher in SPE group than in control group (P = 0.011). Conclusions: The implication is that the PPP1R12A gene may be a disease-susceptibility gene for SPE.","PeriodicalId":13054,"journal":{"name":"Hypertension in Pregnancy","volume":"40 1","pages":"88-96"},"PeriodicalIF":1.5,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10641955.2021.1872613","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38834188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Effects of slow and deep breathing on reducing obstetric intervention in women with pregnancy-induced hypertension: a feasibility study protocol. 慢速深呼吸对减少妊娠高血压妇女产科干预的影响：可行性研究方案。

IF 1.5 4区医学

Hypertension in Pregnancy Pub Date : 2021-02-01 Epub Date: 2021-01-19 DOI: 10.1080/10641955.2020.1869250

M Felton, V A Hundley, S Grigsby, A K McConnell

引用次数: 0

Patients' perspective on aspirin during pregnancy: a survey. 孕妇对阿司匹林的看法:一项调查。

IF 1.5 4区医学

Hypertension in Pregnancy Pub Date : 2020-11-01 Epub Date: 2020-06-20 DOI: 10.1080/10641955.2020.1777299

Jeske M Bij de Weg, Carolien N H Abheiden, Marjon A de Boer, Conni de Groot, Johanna I P de Vries

引用次数: 3

Methyldopa versus labetalol or no medication for treatment of mild and moderate chronic hypertension during pregnancy: a randomized clinical trial. 甲基多巴与拉贝洛尔或不用药治疗妊娠期轻度和中度慢性高血压：一项随机临床试验。

IF 1.5 4区医学

Hypertension in Pregnancy Pub Date : 2020-11-01 Epub Date: 2020-07-22 DOI: 10.1080/10641955.2020.1791902

Mohamed Rezk, Mohamed Emarh, Alaa Masood, Ragab Dawood, Elsayed El-Shamy, Awni Gamal, Hassan Badr

{"title":"Methyldopa versus labetalol or no medication for treatment of mild and moderate chronic hypertension during pregnancy: a randomized clinical trial.","authors":"Mohamed Rezk, Mohamed Emarh, Alaa Masood, Ragab Dawood, Elsayed El-Shamy, Awni Gamal, Hassan Badr","doi":"10.1080/10641955.2020.1791902","DOIUrl":"10.1080/10641955.2020.1791902","url":null,"abstract":"Objective: to assess the maternal and fetal outcome in women with mild to moderate chronic hypertension on antihypertensive drug (methyldopa or labetalol) therapy compared to no medication.Methods: This multicenter randomized clinical study was conducted at Menoufia University hospital, Shibin El-kom Teaching hospital at Menoufia governorate, Egypt.486 pregnant women with mild to moderate chronic hypertension were randomized into three groups; methyldopa group (n = 164), labetalol group (n = 160), and control or no medication group (n = 162) who were followed from the beginning of pregnancy till the end of puerperium to record maternal and fetal outcome.Results: There was a highly significant difference between treatment groups (methyldopa and labetalol) and control group regarding the development of maternal severe hypertension, development of preeclampsia, renal impairment, presence of ECG changes, placental abruption, and repeated admission to hospital for blood pressure control (p < 0.001) with higher occurrence in the control (no treatment) group. Neonates in the labetalol group were more prone for the development of small for gestational age (SGA), neonatal hypotension, neonatal hyperbilirubinemia, and admission to NICU than their counterparts in the methyldopa and control groups (p < 0.001). The rate of prematurity was significantly higher in the control group than the treatment groups (p < 0.05).Conclusion: Treatment of mild to moderate chronic hypertension during pregnancy is beneficial in decreasing both maternal and fetal morbidity. The use of labetalol was associated with higher rates of SGA, neonatal hypotension, and neonatal hyperbilirubinemia compared to methyldopa or no medication.","PeriodicalId":13054,"journal":{"name":"Hypertension in Pregnancy","volume":"39 4","pages":"393-398"},"PeriodicalIF":1.5,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10641955.2020.1791902","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10588181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

The relationship between circadian blood pressure variability and maternal/perinatal outcomes in women with preeclampsia with severe features. 重度子痫前期妇女昼夜血压变化与孕产妇/围产期结局之间的关系。

IF 1.5 4区医学

Hypertension in Pregnancy Pub Date : 2020-11-01 Epub Date: 2020-08-03 DOI: 10.1080/10641955.2020.1797777

Liuying Zhong, Wenfeng Deng, Weihan Zheng, Shuting Yu, Xiaosi Huang, Yaohong Wen, Philip C N Chiu, Cheuk-Lun Lee

引用次数: 0