揭示氧化应激和脂质状态参数在子痫前期发病中的作用。

IF 1.5 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Hypertension in Pregnancy Pub Date : 2021-05-01 Epub Date: 2021-05-03 DOI:10.1080/10641955.2021.1921790

Petar Cabunac, Nataša Karadžov Orlić, Daniela Ardalić, Gorica Banjac, Jasmina Ivanišević, Jelena Janać, Jelena Vekić, Aleksandra Zeljković, Marija Mihajlović, Nina Rajović, Nataša Milić, Željko Miković

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引用次数: 6

摘要

目的:本研究的目的是评估氧化应激和脂质状态在子痫前期发病中的潜在作用。方法:对138例高危孕妇进行前瞻性随访。评估妊娠期间氧化应激(TAS、TOS、AOPP和SH组)和脂质状态(t-C、LDL-C、HDL-C、TGC、APO-A1、APO-B)。结果:30名妇女出现先兆子痫。TGC、血浆动脉粥样硬化指数、TAS和SH水平在随后发生子痫前期的妇女中更高。结论:氧化应激和脂质状态紊乱在高危妊娠子痫前期的发病中具有潜在的作用。

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Unraveling the role of oxidative stress and lipid status parameters in the onset of preeclampsia.

OBJECTIVE: The aim of the study was to assess the potential role of oxidative stress and lipid status in the onset of preeclampsia.METHODS: 138 high-risk pregnant women were prospectively followed. Assessment of oxidative stress (TAS, TOS, AOPP and SH groups) and lipid status (t-C, LDL-C, HDL-C, TGC, APO-A1, APO-B) was carried out during the pregnancy.RESULTS: 30 women developed preeclampsia. TGC, atherogenic index of plasma, TAS and SH levels were higher in women who subsequently developed preeclampsia (p<0.05).CONCLUSION: Oxidative stress and lipid status disturbance have a potential role in the onset of preeclampsia in high risk pregnancies.

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来源期刊

Hypertension in Pregnancy 医学-妇产科学

CiteScore

3.40

自引率

0.00%

发文量

审稿时长

6 months

期刊介绍： Hypertension in Pregnancy is a refereed journal in the English language which publishes data pertaining to human and animal hypertension during gestation. Contributions concerning physiology of circulatory control, pathophysiology, methodology, therapy or any other material relevant to the relationship between elevated blood pressure and pregnancy are acceptable. Published material includes original articles, clinical trials, solicited and unsolicited reviews, editorials, letters, and other material deemed pertinent by the editors.