Head & Face Medicine最新文献

{"title":"Changing trends in the epidemiology and surgical treatment of benign parotid gland tumours: a 10-year retrospective comparison in a tertiary referral centre of southeast Bavaria.","authors":"Ioannis Michaelides, Luisa Symeou, Joshua Wällisch, Johannes Meier, Christopher Bohr, Julian Künzel","doi":"10.1186/s13005-026-00618-w","DOIUrl":"10.1186/s13005-026-00618-w","url":null,"abstract":"<p><p>BACKGROUND: Benign salivary gland tumors are in general rare. Pleomorphic adenomas (PA) and Warthin’s tumors (WT) make up to 90% of these tumors. Their epidemiology shows significant regional differences but also changes over time. In addition to that, new developments in the surgical approach, like extracapsular dissection (ED), have been introduced. METHODS: We retrospectively analyzed epidemiological and clinical data of 347 patients (184 male and 163 female) treated in the ENT-Department of the University Hospital of Regensburg in 2010/11 and 2020/21 and assessed their changes over time. RESULTS: WT is by far the most common benign tumor of the parotid gland, followed by PA and the age of diagnosis shows an increasing tendency. The hospitalization time showed a significant reduction after a period of ten years. Patients treated with ED are being hospitalized for a shorter period of time. Regular smokers tend to present more WT and are being diagnosed at younger age. Patients with WT have a higher body mass index (BMI) than other patients. CONCLUSIONS: Over the last decade, WT remained the most common benign parotid tumor in Southeast Bavaria, while the implementation of ED has potentially impacted clinical resource utilization coincide with reduced duration of inpatient hospitalization. </p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13088733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147689851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of nasolabial changes following Le Fort Ⅰ maxillary advancement versus Medpor implantation in skeletal class Ⅲ patients.","authors":"Xin Lv, Jingyi Li, Jun Cao, Yuxin Wang, Xudong Yang, Qian Zhang","doi":"10.1186/s13005-026-00620-2","DOIUrl":"10.1186/s13005-026-00620-2","url":null,"abstract":"<p><strong>Objective: </strong>Nasolabial depression is a main aesthetic concern in patients with skeletal Class Ⅲ malocclusion, for which Le Fort Ⅰ maxillary advancement or paranasal Medpor implantation is the major treatment choice. However, the aesthetic changes following these two treatments are unclear. This study aimed to compare the nasolabial modifications following Le Fort Ⅰ advancement and Medpor implantation to provide a reference for in surgical planning.</p><p><strong>Methods: </strong>Twenty skeletal Class Ⅲ patients undergoing Le Fort Ⅰ advancement or paranasal Medpor implantation were retrospectively enrolled (10 in the advancement group and 10 in the implantation group). Spiral CT data were acquired one week preoperatively (T1) and at least 6 months postoperatively (T2) for study. For detailed comparison, the nasolabial region was divided into paranasal and subnasal regions. A total of 26 landmarks were marked, from which 10 linear segments,4 angles, corresponding regional volume and curvature were measured.</p><p><strong>Results: </strong>The average moving distance in advancement group was 5.29 ± 0.53 mm, and the average thickness of the Medpor implant was 6.51 ± 0.72 mm. After surgery in both groups, most of the parameters in the paranasal and subnasal regions increased significantly (P ≤ 0.05), except for nasal length (N'-SN). In the advancement group, the postoperative nasal length (N'-SN) demonstrated a significant reduction compared to preoperative values, whereas in the implantation group, no significant difference was observed in nasal length (N'-SN) after surgery. In the paranasal region, alar width and alar base width showed significantly greater changes in the implantation group than in the advancement group. In the subnasal region, four linear segments, one angle and the corresponding volume and curvature showed significantly greater changes in the advancement group than in the implantation group.</p><p><strong>Conclusion: </strong>Both Le Fort Ⅰ advancement and Medpor implantation can significantly improve paranasal depression. However, compared with Le Fort Ⅰ advancement, Medpor implantation provides limited improvement in subnasal depression but affects more in alar width.</p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13196199/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147653938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can supermicrosurgery treat Alzheimer's disease? - Current evidence and hope.","authors":"Ashkan Rashad, Behrus Hinrichs-Puladi, Henning Wieker, Jeff Berens, Max Ulbrich, Rainer Röhrig, Frank Hölzle, Kathrin Reetz, Maurice Klein","doi":"10.1186/s13005-026-00615-z","DOIUrl":"10.1186/s13005-026-00615-z","url":null,"abstract":"<p><p>Alzheimer’s disease is characterized by a loss of temporal and spatial orientation and a progressive loss of cognitive and locomotor function. Therapeutic drug options are currently limited. There is evidence that degradation products of Alzheimer’s diseases such as the tau protein or amyloid beta in Alzheimer’s disease could be removed by the glymphatic system (lymphatic system of the brain), as these drain into the deep cervical lymph nodes. The microsurgical creation of lympho-venous anastomoses could improve this drainage and improve cognition in Alzheimer’s patients (probably also for other neurodegenerative disorders). To date, however, only a few case studies and small cohort studies have been published. Despite the compelling theoretical rationale, there is currently insufficient evidence to support a therapeutic recommendation. The long-term consequences remain unknown, and a structured, stepwise program of follow-up studies is required to further investigate the proposed association. This narrative review aims to provide an overview of the opportunities as well as critical considerations in this complex field. As head and neck surgeons, we are experienced in head and neck surgery and the armamentarium of our speciality field can be widen by these procedures in the future.</p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13081312/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147627520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is apical periodontitis a matter of microbial diversity or time? A scoping review.","authors":"Sally Mohamed Nazir, Samar Mahmoud M Saied, Mark Ezzat Eskander, Mai M Mansour, Hams Abdelrahman, Rania Mahmoud Elbackly, Hisham Mahmoud Elnawam","doi":"10.1186/s13005-026-00610-4","DOIUrl":"10.1186/s13005-026-00610-4","url":null,"abstract":"<p><p>BACKGROUND: The pathophysiology of apical periodontitis is complicated involving host immunological response, virulence factors, and a diverse microbiome. Understanding how microbial diversity influences lesion size is crucial for improving therapeutic strategies. OBJECTIVE: This scoping review aimed to have an insight through literature to determine whether primary or secondary apical periodontitis lesions of different sizes are correlated with the quantity and diversity of microorganisms or the duration of the disease. METHODS: The Joanna Briggs Institute (JBI) methodology for conducting scoping reviews was followed. A comprehensive electronic search was conducted through PubMed, Scopus, Web of Science, and Google Scholar to identify relevant studies published up to February 2025. In addition, handsearching was performed to identify additional studies that were not retrieved in the electronic search. Eligibility criteria of the screened papers included clinical studies performed in healthy patients with symptomatic or asymptomatic apical periodontitis where microbial analysis was performed. The EndNote Web reference manager (EndNote X9; Thomson Reuters) was used to ingest articles from various sources, categorize the references, and automatically eliminate duplicates. RESULTS: Out of 4010 papers, 132 studies met the inclusion requirements and were added to the current review. Approximately half of the papers examined bacterial diversity in endodontic infections, while just a small percentage discussed lesion size and were identified as randomized clinical trials. Brazil, USA, Germany and China were found to have the highest frequency of published articles. Fusobacteria, Streptococcus, Enterococcus faecalis and Porphyromonas species were the most detected microorganisms responsible for apical pathosis regardless of lesion size, while other microbiomes were associated with large lesions only, such as Olsenella, Lactococcus lactus and HHV-6 with 3% each and HPV with 6.1%. Other microbiomes such as Candida albicans, Filifactor alocis, HSV1, Pyramidobacter piscolens and Phocaeicola abscessus were seen only associated with small sized lesions with 4.3% each. CONCLUSIONS: Microbial diversity and microbial load seem to be a strong determinant of apical lesion size while lesion duration could not be adequately assessed due to cross-sectional study designs. Lesion size is an important variant to be recorded to give insight into microbial diversity and provide the basis for personalized targeted antimicrobial therapies in the future. This scoping review was registered in the open science framework; DOI: https://doi.org/10.17605/OSF.IO/DC95Z . </p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13085567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147591336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic accuracy of the Fonseca anamnestic index for temporomandibular disorders: a systematic review and meta-analysis.","authors":"Feihong Ma, Yayuan Wang, Dan Han, Binkui Jia, Xuehai Liu, Hongfan Li, Zhijing Song","doi":"10.1186/s13005-026-00601-5","DOIUrl":"10.1186/s13005-026-00601-5","url":null,"abstract":"<p><p>OBJECTIVE: This study aimed to comprehensively evaluate the diagnostic accuracy and performance of the Fonseca Anamnestic Index (FAI) in screening for temporomandibular disorders (TMD) through a systematic review and meta-analysis approach. METHODS: A systematic literature search was conducted in PubMed, Cochrane Library, Web of Science, and Embase from database inception to September 2025, using the keywords “Fonseca Anamnestic Index” and “temporomandibular disorders.” The included studies were assessed for risk of bias using QUADAS-2 tool. Threshold effects were examined with Meta-DiSc 1.4 software. Pooled sensitivity, specificity, diagnostic odds ratio (DOR)and area under receiver operating characteristic curve (AUC) were calculated via Stata 15.0. Subgroup analyses, sensitivity analyses, and publication bias assessments were also performed. RESULTS: Out of 571 records identified, nine studies involving 2,381 patients met the inclusion criteria. Spearman correlation coefficient for threshold effect was 0.376 (P = 0.332 > 0.05), indicating no significant threshold effect. Pooled sensitivity and specificity were 0.89 (95% CI: 0.82–0.94) and 0.76 (95% CI: 0.57–0.88), respectively. Positive and negative likelihood ratios were 3.28 (95% CI: 2.46–4.10) and 0.14(95% CI:0.07–0.27), respectively. The pooled DOR was 26.51 (95%CI: 11.66–60.23), and the summary AUC was 0.91 (95% CI: 0.88–0.93). Subgroup analyses indicated no notable fluctuation in diagnostic performance across populations, regions, or sample sizes, while sensitivity analyses confirmed the stability of the results. No significant publication bias was detected by Deeks’ funnel plot asymmetry test (P = 0.41 > 0.05). CONCLUSION: The FAI exhibits high diagnostic accuracy in TMD screening and may serve as a reliable clinical adjunct tool, facilitating early detection of TMD in evidence-based practices. </p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13154442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147573591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative analysis of transversal dentofacial asymmetries using combined 3D jaw and face-scans: a prospective analytical cross-sectional study.","authors":"Johanna Radeke, Franziska Lara Brand, Fatih Kilic, Rudolf Jäger, Stefan Repky, Bernd Georg Lapatki","doi":"10.1186/s13005-026-00617-x","DOIUrl":"10.1186/s13005-026-00617-x","url":null,"abstract":"<p><p>BACKGROUND: The spatial position of the dentition relative to the perioral soft tissues is predominantly documented and evaluated two-dimensionally using cephalometric or photographic methods. However, objective quantitative assessment is difficult with two-dimensional imaging modalities, especially in cases of transverse asymmetries. The aim of this study was to assess the potential of three-dimensional (3D) face-jaw imaging and analysis of transverse deviations using combined 3D surface scans. METHODS: Combined 3D data of the face and jaws of 76 untreated subjects were evaluated. Group A (n = 66) included patients with no evidence of tooth migration beyond the maxillary dental midline (dentMid), e.g., due to premature loss of primary teeth. The patients, whose imaging data showed tooth migration, were assigned to group B (n = 10). All 3D models were evaluated three times each by four examiners, and analysis parameters relevant to facial and dentofacial asymmetries were calculated and described. “True” landmark positions were estimated using a linear mixed-effects model. Variability of relevant results was characterized by standard deviations which were combined using a linear model. For group A, the relationship between the deviations of the dentMid and of the skeletal maxillary midline (maxMP) from the facial midline plane (facMP) was statistically evaluated by calculating the Spearman correlation coefficient. The difference between these deviations was analyzed using the Wilcoxon test. RESULTS: In group A, a median difference of only − 0.4 mm (range: -1.4 – +0.7 mm) was observed between dentMid and maxMP. Corresponding differences for patients assigned to group B were − 0.6 mm (-1.9 – +0.4 mm). The Spearman correlation analysis indicated a strong correlation between the two parameters (𝑟 = 0.84) and the Wilcoxon test indicated no significant difference between these deviations (p = 0.995). CONCLUSIONS: Our quantitative analysis of combined 3D surface scans demonstrates the wide range of the differences between dental and skeletal midline deviations in untreated individuals. The possibility to differentiate skeletal and dental aspects of midline deviations through an approach without X-rays is of particular therapeutical relevance in patients with pronounced skeletal midline deviation, to quantitatively assess the amount of dentoalveolar compensation required to align the dentMid to the facMP. </p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13063653/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147573610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methods for designing patient-specific templates for optimized fitting of autologous bone augmentations in alveolar cleft osteoplasty.","authors":"Tom A Schröder, Philipp Sembdner, Erik Selbmann, Uwe Teicher, Korn Paula, Michaela Buckova, Farahzadi Samaneh, Pradel Winnie, Günter Lauer, Anas Ben Achour","doi":"10.1186/s13005-026-00613-1","DOIUrl":"10.1186/s13005-026-00613-1","url":null,"abstract":"<p><p>BACKGROUND: Following the current gold standard, autologous cancellous bone is used as part of alveolar cleft osteoplasty. To fill the bone defects, autologous bone material is harvested from the iliac crest using manual tools such as shepard chisels or trephine drills. The bone augmentations obtained in this way have a simple geometry, usually cylinders, and must then be manually adapted to the defect to be filled by the surgeon using surgical forceps and scissors. There are no established routines for the manufacturing of patient-specific, cost-effective surgical cutting guides. However, the accuracy of fit of the augmentations plays an important role in the healing process. METHODS: This paper focuses on a concept for the creation of necessary sequenced incision geometries based on 3D X-ray data of alveolar cleft defects. RESULTS: As a result, a procedure is to be developed for the preoperative design of individualised surgical cutting guides based on image data. We described a workflow to segment the cleft defect using reverse engineering from Cone-beam computed tomography (CBCT) data. The data was further processed and a keyhole contour was created. A stamping guide and a cutting guide were then derived. The stamping guides were scaled 5, 10 and 15% larger than the defect. In addition, two half-shells were produced, which will be used to investigate the clamping forces and the biological consequences in a follow-up study. CONCLUSIONS: This article presents a developed routine for creating patient-specific templates and demonstrates its feasibility. </p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13063875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147511720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Kinesio Taping on pain, swelling and trismus after third molar surgical extraction: systematic review and meta-analysis.","authors":"Ali Heidari, MohammadReza Ghorbani Afkhami, Shaghayegh Tavakoli, Mitra Galvani, Sepideh Mojiri, Seyed Alireza Mousavi Fard","doi":"10.1186/s13005-026-00603-3","DOIUrl":"10.1186/s13005-026-00603-3","url":null,"abstract":"<p><p>INTRODUCTION: Kinesio taping (KT) is used after mandibular third-molar surgery, yet its benefits and time course remain uncertain. We evaluated whether KT reduces pain, swelling, and trismus versus no tape. METHODS: PRISMA-2020–conform systematic review and meta-analysis (PROSPERO CRD420251072421). Seven databases (PubMed, Embase.com, Scopus, Web of Science Core Collection, CENTRAL, ScienceDirect, Cochrane Library) plus grey literature were searched from inception to 19 May 2025. Eligible studies were adult randomized trials (parallel or split-mouth) under local anaesthesia; KT (≥10% stretch) was applied within 1 h of closure. Outcomes were pain on VAS immediately and days 2–7; swelling; maximum inter-incisal opening; rescue-analgesic intake; skin reactions; and global improvement. Effects were pooled as mean differences (MD) or Hedges g standardized mean differences (SMD) using REML random-effects with inverse-variance weighting and Hartung–Knapp; heterogeneity used I². Risk of bias used RoB-2. Publication bias used a 24-h funnel plot, Egger’s test (α=0.10), and trim-and-fill. Sensitivity analyses were leave-one-out. Certainty used GRADE. RESULTS: Thirteen randomized trials (2019–2025; n=646) were included; overall risk of bias was high. Pain favoured KT early: SMD −0.88 (95% CI −1.11 to −0.65) at 24 h and −0.91 (−1.33 to −0.50) at 48 h; at day 4 the reduction was uniform (I²=0%) with MD −1.94 (−2.56 to −1.32). By day 7, pain was small and uncertain: SMD −0.66 (−1.48 to 0.15; I²=93%). Swelling showed a small week-one benefit: SMD −0.42 (−0.75 to −0.09; I²=46%). Trismus improved mid-week in single studies (day-4 MD 13.60 mm [10.46 to 16.74]; day-5 MD 5.00 mm [2.56 to 7.44]); pooled day-7 SMD 0.42 (−0.19 to 1.02; I²=83%). Egger’s tests were non-significant except trismus at 2 days (p=0.0003); trim-and-fill imputed zero studies. Early pain findings were robust to leave-one-out. GRADE rated day-7 pain, swelling, and trismus as very low certainty. DISCUSSION: KT yields large early analgesia, a small week-one swelling reduction, and mid-week opening gains chiefly from single studies; interpretation is limited by high bias risk, heterogeneity, variable measurement, and ≤7-day follow-up. CONCLUSIONS: KT may be offered as an adjunct for early symptom control after third-molar extraction; by day 7 effects are small and uncertain. </p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13130453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147493458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interictal thermal pain hypersensitivity and central sensitization in migraine patients: a case-control study using quantitative sensory testing.","authors":"Keisuke Suzuki, Shiho Suzuki, Yasuo Haruyama, Mukuto Shioda, Saro Kobayashi, Ryotaro Hida, Koichi Hirata","doi":"10.1186/s13005-026-00614-0","DOIUrl":"10.1186/s13005-026-00614-0","url":null,"abstract":"<p><p>BACKGROUND: Altered pain processing and central sensitization are key mechanisms underlying migraine. Although quantitative sensory testing (QST) objectively assesses sensory thresholds, its clinical implications in migraine patients are unclear. We hypothesized that migraine patients have lower thermal pain thresholds than controls, reflecting sensory hypersensitivity associated with central sensitization–related features. METHODS: We conducted a single-center case–control study including 130 patients with migraine and 130 sex-matched healthy controls. Thermal QST was performed during headache-free interictal periods using Intercross-220, assessing the heat detection threshold (HDT), cold detection threshold (CDT), thermal sensory limen (TSL), heat pain threshold (HPT), and cold pain threshold (CPT). Symptoms associated with central sensitization were assessed using the Japanese version of the Central Sensitization Inventory (CSI), a self-report questionnaire. RESULTS: Compared with healthy controls, migraine patients had a significantly lower HPT and higher CPT, indicating hypersensitivity to thermal pain, as well as altered HDTs and CDTs, while the TSL did not differ between groups. The CSI score was significantly correlated with migraine-related disability, interictal burden, ictal allodynia, sleep disturbance, and depressive symptoms. CSI scores were also significantly associated with QST pain-related parameters, whereas other clinical measures were not significantly correlated with sensory thresholds. QST-defined interictal allodynia was more prevalent in migraine patients than in controls (19.2% vs. 8.5%). A CSI score ≥ 40, indicating a high burden of central sensitivity–related symptoms, was observed in 30.8% of migraine patients and 0.8% of healthy controls. In migraine patients, a CSI score ≥ 40 identified QST-defined allodynia with 100% sensitivity and 85.7% specificity. CONCLUSIONS : Patients with migraine exhibit interictal hypersensitivity to thermal pain. The CSI may serve as a useful patient-reported tool for identifying symptom burden associated with central sensitization-related sensory hypersensitivity in migraine patients. </p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13123026/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147485360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CBCT-based virtual surgical planning for predicting risk factors and preventive strategies of buccal plate perforation in maxillary premolar implant placement.","authors":"Weihua Zhu, Shengjun Yang, Peng Lin, Zaiou Zhu, Xiaomeng Song","doi":"10.1186/s13005-026-00611-3","DOIUrl":"10.1186/s13005-026-00611-3","url":null,"abstract":"<p><p>BACKGROUND: Buccal plate perforation (BPP) is a common intraoperative complication during implant placement in the maxillary premolar region, compromising implant stability and long-term success. This study aimed to identify CBCT-based risk factors for BPP and develop a predictive model to optimize implant planning. MATERIALS AND METHODS: A retrospective analysis of cone beam computed tomography (CBCT) scans from 252 patients with missing maxillary premolars was performed. Virtual implant simulation evaluated the effects of alveolar bone type, alveolar bone inclination angle (ABIA), tooth position, and implant-to-bone angulation (IBA) on BPP incidence. Significant variables identified by Chi-squared and t-tests were further analyzed using multivariate logistic regression and receiver operating characteristic (ROC) analysis to determine predictive thresholds. RESULTS: Sex, tooth position, alveolar bone type, ABIA, and IBA were significantly associated with BPP (P < 0.05). Female patients, first premolar sites, and buccally projected-concave bone types showed higher risk. BPP risk increased when ABIA ≥ 24.94° or IBA ≥ 20.71°, whereas a 1 mm palatal shift from the alveolar ridge center reduced its incidence from 34.69% to 7.1% with minimal palatal perforation (2.6%). CONCLUSIONS: CBCT-based virtual planning enables individualized risk assessment and optimization of implant trajectory. This study identifies key quantitative thresholds for ABIA and IBA, which, when combined with minor adjustments in implant positioning, provide a robust strategy for improving surgical outcomes. Although these findings are derived from virtual simulations, clinical validation is required to confirm their applicability in real-world clinical settings. </p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13113480/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147473498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}