Impact of postoperative dairy consumption on oral wound healing: critical analysis from a prospective, randomized and controlled trial.

IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE
Tobias Otto, Jan Alfred Dittmann, Jacob Stake, Dirk Szulczewski-Stake, Lukas Schipper, Kai Wermker
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Abstract

Introduction: In the German-speaking community of surgeons addressing the oral cavity, there has long been a prevailing opinion that dairy products could be harmful to oral wound healing, but is this true? This study sheds light on this issue based on clinical data of wound healing impairment rates.

Methods: A patient questionnaire, clinical examination prior to surgery of the oral cavity and a postoperative examination at suture removal were used to assess whether altered wound healing impairment rates occurred because of dairy product consumption. This was done in the setting of a prospective, randomized, controlled, single-blinded, bicenter study in outpatient and inpatient settings.

Results: Among the 257 patients participating 228 were included in the study, 227 had complete data sets and were used for our statistical analysis. The cohort was randomly divided into 105 dairy product consumers (intervention group) and 123 without dairy products (control group). In total, 45 wound healing impairments out of 227 patients (19.82%) were noted, including 20 (19.05%) in the group of dairy product consumers (intervention group) and 25 (20.33%) in the control group. The logistic regression model was unable to show a statistically significant association between dairy product consumption and wound healing impairment. (p = 0.26), (OR = 0.65). The study found no statistically significant associations that dairy product consumption has either a negative or positive effect on wound healing. (p = 0.26), (OR = 0.65).

术后乳制品消费对口腔伤口愈合的影响:一项前瞻性、随机和对照试验的关键分析。
导言:在德语社区的口腔外科医生中,长期以来普遍认为乳制品可能对口腔伤口愈合有害,但这是真的吗?本研究基于伤口愈合损伤率的临床数据,揭示了这一问题。方法:采用患者问卷调查、口腔术前临床检查和术后拆线检查来评估是否因食用乳制品而改变了伤口愈合损伤率。这是一项前瞻性、随机、对照、单盲、双中心的门诊和住院研究。结果:参与研究的257例患者中,228例纳入研究,其中227例有完整的资料集,用于我们的统计分析。研究对象随机分为食用乳制品者105人(干预组)和不食用乳制品者123人(对照组)。227例患者中有45例(19.82%)出现伤口愈合损伤,其中乳制品消费者组(干预组)20例(19.05%),对照组25例(20.33%)。logistic回归模型无法显示乳制品消费与伤口愈合损伤之间有统计学意义的关联。(p = 0.26), (OR = 0.65)。该研究发现,乳制品消费对伤口愈合有积极或消极影响,在统计上没有显著的关联。(p = 0.26), (OR = 0.65)。
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来源期刊
Head & Face Medicine
Head & Face Medicine DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
4.70
自引率
3.30%
发文量
32
审稿时长
>12 weeks
期刊介绍: Head & Face Medicine is a multidisciplinary open access journal that publishes basic and clinical research concerning all aspects of cranial, facial and oral conditions. The journal covers all aspects of cranial, facial and oral diseases and their management. It has been designed as a multidisciplinary journal for clinicians and researchers involved in the diagnostic and therapeutic aspects of diseases which affect the human head and face. The journal is wide-ranging, covering the development, aetiology, epidemiology and therapy of head and face diseases to the basic science that underlies these diseases. Management of head and face diseases includes all aspects of surgical and non-surgical treatments including psychopharmacological therapies.
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