Head & Face Medicine最新文献

{"title":"Evaluation the impact of access cavity design and activation of calcium silicate-based sealer with EDDY and XP-Endo Finisher on sealer penetration into dentinal tubules: a confocal laser scanning microscopy study.","authors":"Merve Sarı, Pelin Tüfenkçi","doi":"10.1186/s13005-025-00530-9","DOIUrl":"https://doi.org/10.1186/s13005-025-00530-9","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate the effects of access cavity design and activation procedures on the penetration depth and bond strength of calcium silicate-based sealers to dentin, while also distinguishing the influence of the root level as an anatomical reference point.</p><p><strong>Methods: </strong>Sixty-six mandibular molars were randomly divided into two groups based on the access cavity design (traditional (TEC) or conservative (CEC)). The distal root canals were prepared using Reciproc files (40.06). The fluorescent calcium tracer Fluo-3 was added to the calcium silicate- based sealer CeraSeal to evaluate sealer penetration into dentinal tubules in confocal laser scanning microscopy (CLSM).Each access cavity group was further divided into three subgroups according to the sealer activation technique (Non-activation (NA), EDDY, XP-Endo Finisher (XP-F)) (n = 11). Root slices of 2.0 mm thickness (± 0.1 mm) were obtained at 3-5 mm and 8-10 mm from the root apex for CLSM to evaluate the percentage of sealer penetration. The bond strength was assessed with an Instron machine. Statistical analysis was performed using three-way ANOVA with Bonferroni correction, with the significance level set at 0.05.</p><p><strong>Results: </strong>There were no significant interaction effects among the independent variables (access cavity design, activation procedures and root level) (P > 0.05); however, each variable individually showed a significant main effect on both the percentage of sealer penetration and bond strength (P < 0.001). A significant main effect of access cavity design was observed, with TECs exhibiting significantly higher values than CECs in both outcomes (P < 0.001). Similarly, the root level significantly influenced results, with greater sealer penetration and bond strength at 9 mm compared to 4 mm (P < 0.001). The activation procedure also had a significant impact (P < 0.001). Post hoc comparisons using the Bonferroni correction revealed that both EDDY and XP-F significantly improved sealer penetration and bond strength compared to no activation (NA) (P < 0.001). However, no statistically significant difference was observed between EDDY and XP-F (P > 0.05).</p><p><strong>Conclusion: </strong>The TEC design, the use of EDDY and XP-Endo Finisher activation techniques and the examination of coronal root levels resulted in a greater percentage in sealer penetration and higher values of bond strength.</p><p><strong>Trial registrations: </strong>Clinical Trial Number: Not applicable.</p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":"21 1","pages":"54"},"PeriodicalIF":2.4,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144717846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of three different apical termini on postoperative pain in teeth with irreversible pulpitis: a prospective clinical study.","authors":"Fei Zhai, Haiying Zhang, Chen Zhang, Benxiang Hou","doi":"10.1186/s13005-025-00531-8","DOIUrl":"10.1186/s13005-025-00531-8","url":null,"abstract":"<p><strong>Background: </strong>The apical terminus of root canal preparation plays a critical role in minimizing postoperative pain. Yet, significant debate remains regarding the optimal termination point. This prospective clinical study aimed to assess the effect of three different apical termini on postoperative pain in teeth with irreversible pulpitis.</p><p><strong>Methods: </strong>Totally, 128 patients with asymptomatic or symptomatic irreversible pulpitis were consecutively enrolled. Participants underwent root canal preparation with the apical terminus positioned either at the apical foramen (AF) or 0.5 or 1 mm short of it. Pain intensity was rated using an 11-point numerical rating scale (NRS-11) at nine time points. Data were analyzed using repeated measures analysis of variance.</p><p><strong>Results: </strong>In cases of irreversible pulpitis without preoperative pain (NRS = 0), the pain scores at 72 h after preparation were significantly lower in the AF-1 mm group than in the AF group (P < .05), with none of the patients in the AF-1 mm group reporting pain at this time point (P < .017). In cases of irreversible pulpitis with moderate preoperative pain (NRS = 4-7), the post-preparation pain scores at 4 h was significantly lower than the preoperative pain in all groups (P < .05). The pain scores in the AF-0.5 mm group remained lower than that in the other groups at 4 h, 24 h, 72 h, and 1 week. More patients reported decreased pain 4 h postoperatively in the AF-0.5 mm group than in other groups, with all patients in the AF-0.5 mm group reporting no pain at 1 week. In cases with mild preoperative pain (NRS = 1-3), the pain scores were significantly lower 72 h postoperatively than preoperatively (P < .05), with fewer patients reporting increased pain 24 h postoperatively in the AF-0.5 mm group than other groups.</p><p><strong>Conclusions: </strong>Positioning the root canal apical terminus 0.5 and 1.0 mm short of the AF in symptomatic and asymptomatic cases of irreversible pulpitis, respectively, was most effective in reducing the severity and duration of postoperative pain. Tailoring apical preparation depth to the pulpal condition-symptomatic or asymptomatic-can optimize patient comfort and support more personalized endodontic care.</p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":"21 1","pages":"53"},"PeriodicalIF":2.4,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12278658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144682465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral hygiene, dental caries, and periodontal status in the migrant population. A systematic review, a 10-year study.","authors":"Alma Graciela Garcia-Calderon, Maria Verónica Cuevas-Gonzalez, Juan Carlos Cuevas-Gonzalez, León Francisco Espinosa-Cristóbal, Simón Yobanny Reyes-López, Karla Lizette Tovar-Carrillo, Rosa Alicia Saucedo-Acuña, Graciela Zambrano-Galván, José Luis Osornio-Rojas, Luis Felipe Fornelli-Martin Del Campo, Ixchel Araceli Maya-Garcia","doi":"10.1186/s13005-025-00527-4","DOIUrl":"10.1186/s13005-025-00527-4","url":null,"abstract":"<p><p>A migrant is a person who moves away from his or her place of habitual residence, whether within a country or across an international border, temporarily or permanently, and for a variety of reasons. Migrant population presents significant challenges in maintaining optimal oral health, because of the limitation in access to a balanced diet, excessive consumption of processed foods or those with a high percentage of sugars, as well as the cost of acquiring hygiene items such as toothbrushes or toothpaste, coupled with the lack of access to public services, they comprise a highly vulnerable population to developing oral disease.</p><p><strong>Objective: </strong>This study aimed to identify and synthesize the oral health characteristics of migrant populations as reported in the literature. A search was conducted for articles that included studies that had some type of report on the oral health status of a migrant population. A bibliographic search was performed in the PubMed, ScienceDirect and Scopus databases from 2016 to 2025 using the keywords: \"immigrants\", \"emigration\", \"oral health\", \"dental caries\" and \"periodontal disease\". To perform the risk of bias analysis, the Joanna Briggs Institute tool for cross-sectional studies was used.</p><p><strong>Results: </strong>Twenty-one studies were selected, nine studies were conducted on migrants of multiple nationalities, in 10 studies (45.4%), oral health characteristics were self-reported by participants, whereas in 11 studies (54.6%), assessments were conducted by a qualified examiner. Based on the reported caries indices, caries experience among the studied populations ranged from 5.5 to 30.9 affected teeth, Regarding the presence of periodontal disease, seven studies reported findings ranging from gingival bleeding to positive results indicating the loss of dental support, and oral lesions were only reviewed in two studies, the most common lesions reported were leukoplakia and fibrous lesions.</p><p><strong>Conclusion: </strong>The evidence suggests that migrants try to maintain the custom of having a diet as natural as possible, but this may be diminished by the economic factor or by a process of resilience. The migrant individuals are characterized by limited access to health services, coupled with their limited economic resources, which makes them susceptible to developing oral diseases. This is corroborated by the high incidence of dental caries and bleeding gums. One of the main limitations of the study was the period (2016-2025) that was selected, which does not represent the totality of what has been published on the subject.</p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":"21 1","pages":"52"},"PeriodicalIF":2.4,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12261718/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application value of indocyanine green lymphography in the management of stage I/IIA microcystic lymphatic malformation of the tongue.","authors":"Tao Han, Lijun Shi, Songming Huang, Weimin Shen","doi":"10.1186/s13005-025-00529-2","DOIUrl":"10.1186/s13005-025-00529-2","url":null,"abstract":"<p><strong>Background: </strong>This study aims to investigate whether indocyanine green lymphography (ICGL) facilitates the effectiveness and accuracy of current management of lingual microcystic lymphatic malformation (mLM).</p><p><strong>Methods: </strong>This retrospective included patients under 18 years old with mLM of the tongue staged I or IIA, who underwent ICGL-aided surgical resection and sclerotherapy (ICGL group) or only surgical resection and sclerotherapy (non-ICGL group) between January 2019 and June 2024. The peri- and postoperative parameters of safety and feasibility were compared between two groups.</p><p><strong>Results: </strong>A total of 42 patients were included, 19 of whom received ICGL-guidance and the other 23 were in non-ICGL group. The comparison of baseline data between the two groups revealed no significant difference. Compared to the non-ICGL group, the ICGL group demonstrated superior efficacy (P = 0.017) and required fewer subsequent treatment sessions (P = 0.027), but had longer operative duration (P = 0.001). No significant differences were observed in terms of postoperative complications, length of hospital-stay, and follow-up period.</p><p><strong>Conclusions: </strong>ICGL was associated with improved postoperative outcomes and less subsequent treatment. This technique may provide rational guidance with promising clinical prospects for management of mLM of the tongue.</p><p><strong>Trail registration: </strong>This study was retrospectively registered on clinicaltrials.gov: NCT06755905, date of registration: January 20, 2025.</p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":"21 1","pages":"51"},"PeriodicalIF":2.4,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of pacifier design on pacifier-palate contact: a finite element analysis.","authors":"Michaela Maintz, Prasad Nalabothu, Florian M Thieringer, Carlalberta Verna","doi":"10.1186/s13005-025-00525-6","DOIUrl":"10.1186/s13005-025-00525-6","url":null,"abstract":"<p><strong>Objective: </strong>The study compares the contact pressure and pressure distribution of various pacifier shapes on the palatal surfaces of newborns and six-month-old infants using nonlinear finite element analysis (FEA). Additionally, it seeks to assess the extent and pattern of interaction between pacifier designs and the lateral and medial zones of the palates.</p><p><strong>Materials and methods: </strong>3D finite element models of four pacifiers (A = NUK^®, B = MAM^®, C = BIBS^®, D = CURAPROX^®) of newborn and six-month-old palate and tongue were developed. The palate geometries were based on dental stone impressions of a neonate and six-month-old infant. The pacifier designs were digitized using computed tomography and analyzed in ANSYS Mechanical 2024 R1 (Ansys, Inc., Canonsburg, USA). Hyperelastic silicone rubber properties were used, while the palate and tongue were modeled as rigid and the mucosa as flexible. The interaction between different pacifier designs and the palate of a newborn was assessed through deformation, contact area, and contact pressure relative to the vertical tongue displacement in the anterior, medial, and lateral zones of the palates.</p><p><strong>Results: </strong>Pacifier D exhibited the highest lateral and medial pressures on both the newborn and six-month-old palates with its broad-winged design. Pacifiers A and B showed moderate but steady increases in lateral pressure. In contrast, pacifier C showed concentrated pressure in the anterior zone with its distinct, rounded shape, particularly on the newborn palate. Pressure distribution patterns differed significantly between pacifier designs, with pacifier D showing the most extensive and uniform pressure distribution across the palate.</p><p><strong>Conclusions: </strong>Pacifier design significantly influences palatal interaction, with broader shapes resulting in higher pressure concentrations on the lateral sides that may affect the transversal palate dimension. Understanding the biomechanical impacts of pacifier use is the first step in giving valuable insights to both clinicians and parents in making informed decisions regarding pacifier selection to support optimal oral development. Further clinical studies are needed to validate these findings.</p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":"21 1","pages":"50"},"PeriodicalIF":2.4,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12247239/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144608180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel dual embedding few-shot learning approach for classifying bone loss using orthopantomogram radiographic notes.","authors":"Pradeep Kumar Yadalam, Amit Rajabhau Pawar, Prabhu Manickam Natarajan, Carlos M Ardila","doi":"10.1186/s13005-025-00528-3","DOIUrl":"10.1186/s13005-025-00528-3","url":null,"abstract":"<p><strong>Background: </strong>Orthopantomograms (OPGs) are essential diagnostic tools in dental and maxillofacial care, providing a panoramic view of the jaws, teeth, and surrounding bone structures. Detecting bone loss, which indicates periodontal disease and systemic conditions like osteoporosis, is crucial for early diagnosis and treatment planning. Periodontists use OPGs to identify subtle radiographic features that signify different stages of bone loss. Automated systems integrating radiographic imaging with textual notes can enhance diagnostic accuracy and minimize interobserver variability. Radiographic notes, which summarize clinical observations and preliminary interpretations, can be utilized for classification through natural language processing techniques, including Transformer-based models. This study will classify bone loss severity (normal, mild, or severe) from OPG notes using a novel dual-embedding few-shot learning framework.</p><p><strong>Methods: </strong>This study used a dataset of radiographic notes from OPGs gathered at Saveetha Dental College and Hospital in Chennai. Bone loss was classified according to Glickman's Classification system. The proposed DualFit model architecture consists of two main branches: a Text Processing Branch for converting textual data into dense vectors and a Feature Processing Branch for analyzing numerical and categorical data. Key techniques such as batch normalization and dropout layers were implemented to improve learning stability and reduce overfitting. A Fusion Layer was utilized to merge outputs from both branches, optimizing classification performance.</p><p><strong>Results: </strong>The DualFit model outperformed leading models like BioBERT, ClinicalBERT, and PubMedBERT. It attained an accuracy of 98.98%, precision of 98.71%, recall of 99.14%, and an F1-score of 98.92%, marking a 5.53% accuracy increase over PubMedBERT. Additionally, the model excelled in multi-class classification tasks, ensuring class balance and achieving near-perfect values for precision, recall, and area under both the ROC and precision-recall curves.</p><p><strong>Conclusions: </strong>The DualFit model significantly advances the automated classification of OPG radiographic notes related to periodontal bone loss. Outperforming existing Transformer-based models streamlines the diagnostic workflow, reduces the workload of radiologists, and enables timely interventions for improved patient outcomes. Future work should explore external validation and integration with multimodal diagnostic systems.</p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":"21 1","pages":"49"},"PeriodicalIF":2.4,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12247381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144608179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New measurement method for long-term oral complications after harvesting buccal mucosa grafts for urethroplasty.","authors":"S Farahzadi, M Buckova, M Von Witzleben, T A Schröder, G Lauer, P Korn","doi":"10.1186/s13005-025-00526-5","DOIUrl":"10.1186/s13005-025-00526-5","url":null,"abstract":"<p><strong>Background: </strong>Patients undergoing oral mucosa harvesting for urethroplasty may experience several challenges during recovery like scarring or changes in oral sensitivity, which can lead to long-term discomfort. In this retrospective study long-term donor site complications after harvesting of oral mucosa for urethroplasty were evaluated and a new measurement method for oral volume differences between the non-operated and operated sides was applied.</p><p><strong>Methods: </strong>Thirty adult male patients who underwent urethroplasty with buccal mucosa grafting were included. At a median of 43 months after surgery, a standardized questionnaire was used, and clinical examinations were conducted to measure the postoperative elasticity of the buccal mucosa. This measurement compared the non-operated side with the operated side. Additionally, we examined descriptive statistics and the influence of smoking status, diabetes mellitus, immunosuppression, alcohol consumption, and graft size.</p><p><strong>Results: </strong>In total, 36% of the patients reported persistent subjective postoperative impairments, such as tightness in the oral cavity or numbness. In all patients, a difference in buccal volume was observed between the operated side and the non-operated side. This volume difference ranged from 3 to 15 ml (mean 8.10 ml, SD ± 3.4; p < 0.001). As the size of the harvested transplant increased, the postoperative buccal volume difference also increased significantly (p < 0.001). In one patient, follow-up surgery was required due to the severity of scarring. The presence of diabetes mellitus, immunosuppressive medication, smoking status, and alcohol consumption had no statistically significant effect on postoperative buccal elasticity or mouth opening.</p><p><strong>Conclusions: </strong>The use of buccal mucosa grafts for urethroplasty is an established procedure in urology, but the oral harvesting procedure can lead to scarring within the buccal area, which is associated with a statistically significant decrease in buccal volume compared with the non-operated site. The volume analysis was performed by applying a new measurement method, which enables, for the first time, the quantification of oral donor site morbidity.</p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":"21 1","pages":"48"},"PeriodicalIF":2.4,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12239327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cytotoxic and antifungal effects of different teething oral gels: an in-vitro study.","authors":"Aslı Aşık, Ece Bayır, Sibel Acar, Ceren Sağlam, Dilşah Çoğulu, Ataç Uzel","doi":"10.1186/s13005-025-00524-7","DOIUrl":"10.1186/s13005-025-00524-7","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;This study aimed to evaluate the effects of various teething oral gels, containing lidocaine, hyaluronic acid, and herbal-based ingredients, on cell viability and to compare the antifungal properties.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Materials and methods: &lt;/strong&gt;The effect of the six different teething oral gels (Gengigel Teething, Orajel Baby, Calgel, Hyland's Baby Organic Soothing Gel, Buccotherm Teething Gel and Aftamed Teething) on cell viability was evaluated through the MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide) assay on L-929 mouse fibroblast cells. The antifungal activity of teething oral gels against Candida albicans ATCC 90,028, C. tropicalis ATCC 750, C. glabrata ATCC 2001, C. parapsilosis ATCC 22,019, and C. krusei ATCC 6258 was assessed using the broth dilution method.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The cell viability analysis revealed that Aftamed Teething exhibited the highest level of cytotoxicity among the tested teething oral gel products, whereas Buccotherm Teething Gel demonstrated the lowest cytotoxicity. The teething oral gels can be ordered based on their respective cytotoxicity profiles: Aftamed Teething (IC&lt;sub&gt;50&lt;/sub&gt; 4.62 mg/ml) &gt; Calgel (IC&lt;sub&gt;50&lt;/sub&gt; 33.40 mg/ml) &gt; Gengigel Teething (IC&lt;sub&gt;50&lt;/sub&gt; 122.85 mg/ml) &gt; Orajel Baby (IC&lt;sub&gt;50&lt;/sub&gt; 137.13 mg/ml) &gt; Hyland's Baby Organic Soothing Gel (IC&lt;sub&gt;50&lt;/sub&gt; 229.20 mg/ml) &gt; Buccotherm Teething Gel (IC&lt;sub&gt;50&lt;/sub&gt; 284.38 mg/ml) (p &lt; 0.05). The results indicate that Buccotherm Teething Gel, Hyland's Baby Organic Soothing Gel and Orajel Baby did not exhibit any antifungal activity against C. albicans, while Gengigel Teething and Aftamed Teething demonstrated marginal effects at the 100 mg/ml concentration threshold. The Calgel exhibited the highest efficacy against C. albicans, with a minimum inhibitory concentration of 12.5 mg/ml (p &lt; 0.05). From non-albicans Candida species, it was ascertained that Gengigel exhibited a modest antifungal effect on C. tropicalis and C. parapsilosis, while Calgel demonstrated a modest antifungal effect on C. glabrata. Additionally, Calgel demonstrates antifungal activity against C.tropicalis and C.parapsilosis, with a minimum inhibitory concentration of 25 mg/ml (p &lt; 0.05).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Teething oral gels containing lidocaine, hyaluronic acid, and herbal formulations demonstrated varying degrees of cytotoxicity and antifungal efficacy. Herbal-based teething oral gels may be a more suitable option for young children compared to products containing lidocaine or hyaluronic acids, as they exhibit reduced cytotoxicity and enhanced biocompatibility. Lidocaine-containing gel may be preferred for opportunistic fungal infections, considering their high cytotoxic properties, solely to leverage their antifungal capabilities on different species.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Clinical relevance: &lt;/strong&gt;Lidocaine-containing teething oral gel has demonstrated potent antifungal properties on both C.","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":"21 1","pages":"47"},"PeriodicalIF":2.4,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12228206/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144564672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between psychological factors and temporomandibular disorders: a systematic review and meta-analysis.","authors":"Ravinder S Saini, Syed Altafuddin Quadri, Seyed Ali Mosaddad, Artak Heboyan","doi":"10.1186/s13005-025-00522-9","DOIUrl":"10.1186/s13005-025-00522-9","url":null,"abstract":"<p><strong>Background: </strong>Temporomandibular disorders (TMD) are multifactorial conditions that involve pain, dysfunction, and impaired jaw movement, significantly impacting patients' quality of life. Emerging evidence suggests that psychological factors, including anxiety, depression, and stress, play a crucial role in the onset and progression of TMD. However, the exact nature of this relationship remains unclear. This study aims to systematically analyze and quantify the association between psychological factors and TMD, providing clinically relevant insights to improve patient management and therapeutic strategies.</p><p><strong>Methods: </strong>This study was registered with the International Platform of Registered Systematic Review and Meta-Analysis Protocols (INPLASY202420084) to ensure methodological transparency and adherence to systematic review standards. The study design and protocol followed the Preferred Reporting of Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The National Institutes of Health (NIH) Quality Assessment Tool was used to assess the methodological quality of the included studies. The data were systematically extracted and analyzed.</p><p><strong>Results: </strong>The literature search yielded 2392 potential articles, of which 21 were included in this study. A significant correlation was found between TMD and anxiety, depression, stress, and somatization. Statistically significant differences in anxiety and depression scores were observed between patients with TMD and the controls (p < 0.00001). Stress increased TMD development and severity. In addition, subgroup analyses revealed gender differences, with depression significantly correlating with TMD in males. Similarly, students showed significant correlations between TMD and anxiety, while adults demonstrated strong associations with both anxiety and depression. Adolescents showed correlations between TMD development and somatization and obsessive-compulsiveness.</p><p><strong>Conclusion: </strong>Anxiety, depression, and stress are significant risk factors for the development and progression of TMD. Subgroup analyses demonstrated significant correlations between particular psychological factors and TMD in different sub-populations.</p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":"21 1","pages":"46"},"PeriodicalIF":2.4,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12175401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144325516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimization of the size and location of the FOVs for CBCT capture of impacted lower third molars.","authors":"Marc Anton Fuessinger, Maximilian Frederik Russe, Leonard Simon Brandenburg, Marc Christian Metzger, Johannes Schulze, Stefan Schlager, Jonas Wuester, Wiebke Semper-Hogg","doi":"10.1186/s13005-025-00518-5","DOIUrl":"10.1186/s13005-025-00518-5","url":null,"abstract":"<p><strong>Background: </strong>Cone beam computed tomography (CBCT) is an established diagnostic tool for impacted wisdom teeth (third molars (3 M)) in proximity of the mandibular nerve canal. This study aims to define the minimum field-of-view (FOV) size and its localization to reduce radiation exposure. As reference, the chin rest of the CBCT device was used.</p><p><strong>Methods: </strong>Three-dimensional CBCT data sets were used to analyze the bilateral positions and dimensions of the wisdom teeth. A total of 215 wisdom teeth from a study population with a mean age of 21 years, including data from 82 male and 58 female patients, were mapped. By transformation into a common coordinate space using the device's chin rest as a joint denominator, the optimal size and location for uni- and bilateral capture of the wisdom teeth were determined, for both best-case and worst-case scenarios with regard to patient positioning.</p><p><strong>Results: </strong>The minimal FOVs for the lower 3 M capture were H 23.5 mm × R 35.4 mm in the best-case scenario assuming optimal patient positioning and H 35.4 mm × R 36.6 mm in the worst-case scenario with rotational deviation along the transversal axis. For the upper 3 M, the minimal FOVs were H 29.9 mm × R 29.2 mm in the best-case scenario and H 38.6 mm × R 35.6 mm in the worst-case scenario. Unilateral capture of both the upper and lower 3 M required FOV dimensions of H 51.7 mm × R 39.8 mm and H 44.8 mm × R 36.8 mm, respectively. For bilateral capture of all four 3 M, the best-case FOV was H 44.8 mm × R 84.8 mm and the worst-case FOV was H 51.7 mm × R 85.6 mm.</p><p><strong>Discussion: </strong>This research provides indication-specific FOVs for uni- and bilateral imaging of the upper and lower 3 M. Taking into account optimal clinical practices for CBCT imaging, this study aims to propose clinically feasible FOV dimensions while meeting the technical specifications of commonly used CBCT devices. Clinical application of the results may help reduce radiation exposure of patients receiving CBCT imaging of the wisdom teeth. Transfer of the present results to other CBCT devices requires further research.</p><p><strong>Trial registration: </strong>The study is registered in the German Trial Register with the number DRKS00026149, 2024/02/21.</p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":"21 1","pages":"45"},"PeriodicalIF":2.4,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12144699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144247649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}