Alexei A Kamshilin, Anton N Konovalov, Fyodor V Grebenev, Igor O Kozlov, Dmitry D Stavtsev, Gennadii A Piavchenko, Ervin Nippolainen, Valeriy V Zaytsev, Alexey Y Sokolov, Dmitry V Telyshev, Sergei L Kuznetsov, Roman V Romashko, Igor V Meglinski
{"title":"Advancing intraoperative cerebral blood flow monitoring: integrating imaging photoplethysmography and laser speckle contrast imaging in neurosurgery.","authors":"Alexei A Kamshilin, Anton N Konovalov, Fyodor V Grebenev, Igor O Kozlov, Dmitry D Stavtsev, Gennadii A Piavchenko, Ervin Nippolainen, Valeriy V Zaytsev, Alexey Y Sokolov, Dmitry V Telyshev, Sergei L Kuznetsov, Roman V Romashko, Igor V Meglinski","doi":"10.1007/s12200-025-00163-5","DOIUrl":"10.1007/s12200-025-00163-5","url":null,"abstract":"<p><p>Intraoperative assessment of cerebral hemodynamics is crucial for the success of neurosurgical interventions. This study evaluates the potential of laser speckle contrast imaging (LSCI) and imaging photoplethysmography (IPPG) for contactless perfusion monitoring during neurosurgery. Despite similarities in their hardware requirements, these techniques rely on fundamentally different principles: light scattering for LSCI and light absorption for IPPG. Comparative experiments were conducted using animals (rats) when assessing the reaction of cerebral hemodynamics to adenosine triphosphate infusion. The results show different spatial and temporal characteristics of the techniques: LSCI predominantly visualizes blood flow in large venous vessels, especially in the sagittal and transverse sinuses, showing a pronounced modulation associated with the heart that cannot be explained by venous blood flow alone. In contrast, IPPG quantifies the dynamics of perfusion changes in the parenchyma, showing minimal signal in large venous vessels. We propose that LSCI signal modulation is significantly influenced by the movement of vessel walls in response to mechanical pressure waves propagating through the parenchyma from nearby arteries. A novel algorithm for LSCI data processing was developed based on this interpretation, producing perfusion indices that align well with IPPG measurements. This study demonstrates that the complementary nature of these techniques (LSCI is sensitive to blood cells displacements, while IPPG detects a change in their density) makes their combined application particularly valuable for comprehensive assessment of cerebral hemodynamics during neurosurgery.</p>","PeriodicalId":12685,"journal":{"name":"Frontiers of Optoelectronics","volume":"18 1","pages":"20"},"PeriodicalIF":5.2,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12463816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tianye Huang, Lin Chen, Mingkong Lu, Jianxing Pan, Chaoyu Xu, Pei Wang, Perry Ping Shum
{"title":"Rapid prediction of complex nonlinear dynamics in Kerr resonators using the recurrent neural network.","authors":"Tianye Huang, Lin Chen, Mingkong Lu, Jianxing Pan, Chaoyu Xu, Pei Wang, Perry Ping Shum","doi":"10.1007/s12200-025-00164-4","DOIUrl":"10.1007/s12200-025-00164-4","url":null,"abstract":"<p><p>Kerr resonator is one of the most popular platforms to produce optical frequency comb and temporal cavity soliton. As an essential method for investigating the nonlinear dynamics of Kerr resonators, traditional numerical simulations rely on solving the Lugiato-Lefever equation (LLE) using the split-step Fourier method (SSFM), which is computationally intensive and time-consuming. To address this challenge, this study proposes a recurrent neural network model with prior information feedback, enabling efficient and accurate prediction of soliton dynamics in Kerr resonator. With the acceleration of graphics processing unit (GPU), the computational efficiency improved by 20 times. We compared various recurrent neural networks and found that the gated recurrent unit (GRU) network demonstrated superior performance in this task. This work highlights the potential of artificial intelligence (AI) for modeling nonlinear optical dynamics in Kerr resonator, paving the way for designing optical frequency comb and generating ultrafast pulse.</p>","PeriodicalId":12685,"journal":{"name":"Frontiers of Optoelectronics","volume":"18 1","pages":"19"},"PeriodicalIF":5.2,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12463783/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advances in tissue optical clearing for 3D imaging in large animal.","authors":"Yating Deng, Jianyi Xu, Tingting Yu, Dan Zhu","doi":"10.1007/s12200-025-00162-6","DOIUrl":"10.1007/s12200-025-00162-6","url":null,"abstract":"<p><p>Three-dimensional reconstruction of tissue architecture is crucial for biomedical research. Tissue optical clearing technology overcomes light scattering limitations in biological tissues, providing an essential tool for high-resolution three-dimensional imaging. Given the high degree of similarity between large model animals (e.g., pigs, non-human primates) and humans in terms of anatomical structure, physiologic function, and disease mechanisms, the application of this technology in these models holds significant value for biomedical research. While well-established tissue clearing protocols exist for tissue sections, whole organs, and even entire bodies in rodents, scaling up to large animal specimens presents substantial challenges due to dimensional effects and compositional variations. This review systematically examines the methodological translation from rodent to large animals, particularly on species-specific differences in brain architecture and parenchymal organ composition that critically impact clearing efficiency. We comprehensively summarize recent applications in large animals, focusing on representative areas including neural circuit mapping, sensory organ imaging, and other related research domains, while proposing optimization strategies to overcome cross-species compatibility barriers. We hope this review will serve as a valuable reference for advancing tissue optical clearing applications in large-animal biomedical research.</p>","PeriodicalId":12685,"journal":{"name":"Frontiers of Optoelectronics","volume":"18 1","pages":"18"},"PeriodicalIF":5.2,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12361029/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144872887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"WGM microprobe device for high-sensitivity ultrasound detection and vibration spectrum measurement.","authors":"Jialve Sun, Shengnan Huangfu, Tinglan Chen, Zijing Cai, Bowen Ruan, Fangxing Zhang","doi":"10.1007/s12200-025-00161-7","DOIUrl":"10.1007/s12200-025-00161-7","url":null,"abstract":"<p><p>Whispering-gallery-mode (WGM) microcavities have emerged as a promising alternative to traditional ultrasound probes, offering high sensitivity and wide bandwidth. In our research, we propose a novel silica WGM microprobe device, with impressive Q factors up to 10<sup>7</sup>. The side-coupled approach and special encapsulation design make the device compact, robust, and capable of utilizing in both gaseous and liquid environments. We have successfully conducted photoacoustic (PA) imaging on various samples using this device which demonstrates a high sensitivity of 5.4 mPa/√Hz and a broad bandwidth of 41 MHz at -6 dB for ultrasound. And it is capable of capturing the vibration spectrum of microparticles up to a few hundred megahertz. Our compact and lightweight device exhibits significant application potential in PA endoscopic detection, near-field ultrasound sensing and other aspects.</p>","PeriodicalId":12685,"journal":{"name":"Frontiers of Optoelectronics","volume":"18 1","pages":"17"},"PeriodicalIF":5.2,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12354358/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144855012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Precision vertical drawing of diameter-gradient microfibers: cascaded geometries for tailored nonlinearity.","authors":"Hao Chi, Xinying He, Dezhou Lu, Shuoyang Wang, Jiahui Wu, Mengyang Jin, Xueliang Li, Zhuning Wang, Yaoguang Ma","doi":"10.1007/s12200-025-00160-8","DOIUrl":"10.1007/s12200-025-00160-8","url":null,"abstract":"<p><p>As nonlinearity is highly correlated with their geometric dimensions, precise fabrication of optical micro/nanofibers (MNFs) has been a longstanding pursuit. Existing MNFs fabrication systems typically adopt horizontal structures, which inherently introduce inaccuracy stem from asymmetry between fiber axis/geometry and chaotic environment due to high temperature airflow, vibration, etc., leading to deviations from the expected fiber morphology, especially for complex-structured MNFs. Here, we propose and manufacture a MNFs fabrication systems, effectively reducing fiber shape deviations during the fabrication process, enabling the fabrication of precise MNFs. To demonstrate the capability of our system in manufacturing precise structure MNFs, we design and fabricate diameter-gradient microfibers with four cascaded structures over a length of approximately 120 mm and a minimum diameter of about 1 μm for on-demand nonlinearity to generate supercontinuum spectrum. Eventually, we obtain supercontinuum spectrum covering 1463-1741 nm at the - 10 dB level with an efficiency of 264.62 <math><mrow><mtext>nm</mtext> <mo>/</mo> <mtext>kW</mtext></mrow> </math> , exhibiting good flatness and enabling efficient spectral broadening.</p>","PeriodicalId":12685,"journal":{"name":"Frontiers of Optoelectronics","volume":"18 1","pages":"16"},"PeriodicalIF":5.2,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12321704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144775244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unveiling local molecular desorption dynamics using higher-order optical resonances.","authors":"Mingquan Deng, Xiujie Dou, Xiaoyu Wang, Yin Yin, Xun Guan, Libo Ma, Xing Ma, Jiawei Wang","doi":"10.1007/s12200-025-00159-1","DOIUrl":"10.1007/s12200-025-00159-1","url":null,"abstract":"<p><p>Understanding the sorption dynamics between water molecules and various solid surfaces is of great interest in diverse fundamental and industrial research. For studying such dynamics in a microsystem, existing investigations mainly focus on sorption behaviors mediated by external temperature variations. Here, we demonstrate a route to in situ sensitive detection of laser irradiation-induced localized water molecule desorption at a sub-monolayer level on an oxide surface. Harnessing a tailored set of optical whispering-gallery-mode (WGM) resonances in a nanomembrane-based microtube cavity, the desorption can be tracked by resonance mode shift in real-time, and further explained using a combination of pseudo-first-order and pseudo-second-order models. Additionally, upon adjusted laser excitation locations, the axial-mode-dependent responses enable the retrieval of corresponding profiles of desorption-induced perturbation at equilibrium. This study provides new insights into molecular desorption kinetics and introduces a spatially resolved sensing technique with applications in surface science, molecular sensing, and the study of desorption dynamics at the nanoscale.</p>","PeriodicalId":12685,"journal":{"name":"Frontiers of Optoelectronics","volume":"18 1","pages":"15"},"PeriodicalIF":5.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12304327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144729681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recent advances in monolithic-integrated lead-based optoelectronic devices.","authors":"Shaoheng Xu, Jiajun Luo, Haisheng Song, Jiang Tang","doi":"10.1007/s12200-025-00158-2","DOIUrl":"10.1007/s12200-025-00158-2","url":null,"abstract":"<p><p>Optoelectronic devices, including light sensors and light-emitting diodes, are indispensable for our daily lives. Lead-based optoelectronic materials, including colloidal quantum dots and lead-halide perovskites, have emerged as promising candidates for the next-generation optoelectronic devices. This is primarily attributed to their tailorable optoelectronic properties, industrialization-compatible manufacturing techniques, seamless integration with silicon technology and excellent device performance. In this perspective, we review recent advancements in lead-based optoelectronic devices, specifically focusing on photodetectors and active displays. By discussing the current challenges and limitations of lead-based optoelectronics, we find the exciting potential of on-chip, in-situ fabrication methods for realizing high-performance optoelectronic systems.</p>","PeriodicalId":12685,"journal":{"name":"Frontiers of Optoelectronics","volume":"18 1","pages":"13"},"PeriodicalIF":4.1,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12158882/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hongqing Li, Wenjing Tang, Yingshuang Shan, Jing Wang, Kai Jiang, Mingqi Fan, Tao Chen, Cheng Zhou, Wei Xia
{"title":"Nonlinear saturable absorption properties of BP/ReS<sub>2</sub> heterojunction and its application in 2 μm all-solid-state lasers.","authors":"Hongqing Li, Wenjing Tang, Yingshuang Shan, Jing Wang, Kai Jiang, Mingqi Fan, Tao Chen, Cheng Zhou, Wei Xia","doi":"10.1007/s12200-025-00157-3","DOIUrl":"10.1007/s12200-025-00157-3","url":null,"abstract":"<p><p>For 2 μm all-solid-state lasers, pulse modulation methods based on low-dimensional nanomaterial saturable absorbers (SAs) offer advantages such as compact structure, low cost, and ease of implementation. The construction of stable, highly nonlinear low-dimensional nanomaterial SAs is an urgent issue to be addressed. In this paper, two types of black phosphorus/rhenium disulfide (BP/ReS<sub>2</sub>) heterojunction with high stability were prepared separately by liquid phase exfoliation (LPE) and mechanical exfoliation (ME) methods, the nonlinear saturable absorption characteristics of the two types of heterojunctions have been characterized in detail. Then, the pulse modulation applications of these two materials have been studied in a 2 μm all-solid-state thulium-doped yttrium aluminum perovskite (Tm:YAP) passively Q-switched pulsed laser. The BP/ReS<sub>2</sub> heterojunction SA prepared by the LPE method demonstrates a thinner thickness and lower non-saturation optical loss, which achieved the maximum average output power 528 mW at a pump power of 6.37 W, with a narrowest pulse width of 366 ns, and a maximum peak power of 28.85 W. These results indicate that the BP/ReS<sub>2</sub> heterojunction SA has great potential for optical modulation device applications.</p>","PeriodicalId":12685,"journal":{"name":"Frontiers of Optoelectronics","volume":"18 1","pages":"14"},"PeriodicalIF":4.1,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12158896/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of energy back transfer from Er<sup>3+</sup> to Yb<sup>3+</sup> ions on the upconversion luminescence of Er:NaYb(MoO<sub>4</sub>)<sub>2</sub> and Yb,Er:NaBi(MoO<sub>4</sub>)<sub>2</sub>.","authors":"Miaomiao Wang, Mengyu Zhang, Shoujun Ding, Haitang Hu, Chuancheng Zhang, Yong Zou","doi":"10.1007/s12200-025-00155-5","DOIUrl":"10.1007/s12200-025-00155-5","url":null,"abstract":"<p><p>Under the excitation of a 980 nm laser, the visible upconversion (UC) luminescence of Er<sup>3+</sup> ions doped Yb<sup>3+</sup> ions self-activated NaYb(MoO<sub>4</sub>)<sub>2</sub> phosphor and crystal, as well as the Yb<sup>3+</sup>/Er<sup>3+</sup> ions codoped NaBi(MoO<sub>4</sub>)<sub>2</sub> crystal were investigated comprehensively. The results indicate that all three samples exhibit two significant green emission bands and a weak red emission band in the visible band corresponding to the transitions of <sup>2</sup>H<sub>11/2</sub>/<sup>4</sup>S<sub>3/2</sub> → <sup>4</sup>I<sub>15/2</sub> and <sup>4</sup>F<sub>9/2</sub> → <sup>4</sup>I<sub>15/2</sub> of Er<sup>3+</sup> ions, respectively. Through the variable power density spectra of three different samples, the relationship between the energy back transfer (EBT) process of Yb<sup>3+</sup>-Er<sup>3+</sup> ions and the power density point and Yb<sup>3+</sup> ion concentration was investigated. The EBT process was observed in both the Er<sup>3+</sup> ions doped Yb<sup>3+</sup> ions self-activated NaYb(MoO<sub>4</sub>)<sub>2</sub> phosphor and crystal, as confirmed by the luminescence image of the sample. At high power density, the Yb<sup>3+</sup> ions self-activated sample exhibited yellow luminescence, with the crystal appearing later than the phosphor. In contrast, the NaBi(MoO<sub>4</sub>)<sub>2</sub> crystal displayed bright green emission within the measured power density range. In addition, by monitoring the relative intensity change of Yb<sup>3+</sup> emission in 5 at% Er<sup>3+</sup>:NaYb(MoO<sub>4</sub>)<sub>2</sub> crystal, the generation of EBT process in self-activated samples at high power density is more directly explained. These experimental results provide a reliable basis for our comprehensive understanding of the EBT mechanism, and also provide a reliable direction for the final determination of the optimal excitation power density for optical temperature measurement.</p>","PeriodicalId":12685,"journal":{"name":"Frontiers of Optoelectronics","volume":"18 1","pages":"12"},"PeriodicalIF":4.1,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12081802/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144077478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Simulation and experimental investigation of liquid-cooling thermal management for high-bandwidth co-packaged optics.","authors":"Senhan Wu, Song Wen, Huimin He, Jianyu Feng, Chuan Chen, Haiyun Xue","doi":"10.1007/s12200-025-00156-4","DOIUrl":"10.1007/s12200-025-00156-4","url":null,"abstract":"<p><p>This study explores the application of cold plate liquid cooling technology in co-packaged optics (CPO). By integrating optical modules and the switch chip on the same substrate, CPO shortens the electrical interconnection distance, effectively solving the problems of high power consumption and poor signal integrity of traditional pluggable optical modules under high bandwidth. However, the surge in power density and the thermal crosstalk resulting from high integration density make thermal management one of the key challenges that constrain the reliability of high-capacity co-packaged optics. For the unique architecture of CPO, this study analyzes its heat dissipation needs in detail, and a thermal management scheme is designed. The thermal management scheme is simulated and optimized based on the Navier-Stokes equation. The simulation results show that, in a 51.2 Tbit/s CPO system, the junction temperature of the switch chip is 97.3 °C, the maximum junction temperature of the optical modules is 31.3 °C, and the temperature difference between the optical modules is 2.4 °C to 1.2 °C. To verify the simulation results, a thermal test experimental platform is built, and the experimental results show that the temperature simulation difference is within 4% and the pressure change trend is consistent with the simulation. Combining the experimental data and simulation results, the designed heat sink can satisfy the heat dissipation demands of the 51.2 Tbit/s bandwidth CPO system. This conclusion demonstrates the potential of liquid-cooling technology in CPO, providing support for research on liquid-cooling technology in the CPO. The design provides a theoretical and practical basis for the high performance and reliability of optoelectronic integration technology in wavelength division multiplexing (WDM) systems and micro-ring device applications, contributing to the application of next-generation optical communication networks.</p>","PeriodicalId":12685,"journal":{"name":"Frontiers of Optoelectronics","volume":"18 1","pages":"11"},"PeriodicalIF":4.1,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12078904/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}