Future cardiology最新文献_第3页

Triple versus double antithrombotic therapy after PCI in atrial arrhythmia: a real-world comparative analysis based on initial antithrombotic strategy using TriNetx. 房性心律失常PCI术后三联抗栓与双联抗栓治疗：基于TriNetx初始抗栓策略的现实世界对比分析。

IF 1.1

Future cardiology Pub Date : 2026-08-01 Epub Date: 2026-08-20 DOI: 10.1080/14796678.2026.2713342

Khaled Elnaggar, Mohammad Hamza, Saif Ali Malik, Kyrillos Mahrous Gerges, Saira Shafiq, Meet Patel, Ali Awad, Roopeessh Vempati, Haidar Hajeh, Muhammad Burhan, Yassine Abdeldjebbar, M Chadi Alraies

{"title":"Triple versus double antithrombotic therapy after PCI in atrial arrhythmia: a real-world comparative analysis based on initial antithrombotic strategy using TriNetx.","authors":"Khaled Elnaggar, Mohammad Hamza, Saif Ali Malik, Kyrillos Mahrous Gerges, Saira Shafiq, Meet Patel, Ali Awad, Roopeessh Vempati, Haidar Hajeh, Muhammad Burhan, Yassine Abdeldjebbar, M Chadi Alraies","doi":"10.1080/14796678.2026.2713342","DOIUrl":"10.1080/14796678.2026.2713342","url":null,"abstract":"Background: The optimal antithrombotic regimen after percutaneous coronary intervention (PCI) in patients with atrial arrhythmias remains uncertain, particularly the balance between double therapy (DT; anticoagulant plus one antiplatelet) and triple therapy (TT; anticoagulant plus dual antiplatelet therapy). Comparative data across coronary artery disease (CAD) phenotypes are limited.Methods: We performed a retrospective cohort study using the TriNetX database, including adults (≥18 years) with atrial fibrillation/flutter undergoing PCI for CAD. Patients receiving TT or DT were matched 1:1 using propensity scores. The primary outcome was a composite of all-cause mortality, ischemic stroke, gastrointestinal bleeding, recurrent myocardial infarction (MI), and repeat PCI. Prespecified subgroup analyses were conducted by CAD phenotype.Results: After matching, 1,332 patients were included (666 per group). TT was associated with a higher incidence of the composite outcome at 1 month (25.08% vs 17.57%), 6 months (35.74% vs 29.13%), and 12 months (42.79% vs 36.04%). TT was also associated with increased recurrent MI, hospitalization/ER visits, and blood transfusion. In subgroup analyses, outcomes were largely similar in STEMI, whereas TT was associated with higher hospitalization/ER visits in NSTEMI/UA.Conclusions: Among CAD patients undergoing PCI, TT was associated with worse clinical outcomes than DT, supporting the need for prospective randomized validation.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"851-863"},"PeriodicalIF":1.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540150/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148791693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparing the effectiveness of home-based and center-based cardiac rehabilitation: a randomized clinical trial. 比较家庭和中心心脏康复的有效性：一项随机临床试验。

IF 1.1

Future cardiology Pub Date : 2026-08-01 DOI: 10.1080/14796678.2026.2708467

Fereshteh Sattar, Marzieh Taheri, Pedram Babaee, Ehsan Shirvani, Hamidreza Roohafza, Faezeh Tabesh, Mohammad Hadi Mansouri, Mohammadmahdi Hadavi, Anahita Babak, Sina Rouhani, Masoumeh Sadeghi

{"title":"Comparing the effectiveness of home-based and center-based cardiac rehabilitation: a randomized clinical trial.","authors":"Fereshteh Sattar, Marzieh Taheri, Pedram Babaee, Ehsan Shirvani, Hamidreza Roohafza, Faezeh Tabesh, Mohammad Hadi Mansouri, Mohammadmahdi Hadavi, Anahita Babak, Sina Rouhani, Masoumeh Sadeghi","doi":"10.1080/14796678.2026.2708467","DOIUrl":"10.1080/14796678.2026.2708467","url":null,"abstract":"Purpose: Center-based cardiac rehabilitation (CR) is the standard of care for patients with cardiovascular disease. However, access limitations have led to increased interest in home-based alternatives. This study aimed to compare the effects of home-based and center-based CR in an Iranian population.Methods: In this randomized controlled trial, 236 patients with cardiovascular disease were randomized to receive either home-based (n = 107) or center-based (n = 129) CR. Interventions lasted 8 weeks, with outcomes assessed at baseline and 6 months. The primary outcome was the change in exercise capacity. Secondary outcomes included exercise capacity, maximum heart rate, blood pressure (BP), lipid profile, fasting blood sugar, body mass index, and waist circumference.Results: Between-group analysis using ANCOVA, adjusting for baseline values, showed that center-based CR was significantly more effective in improving exercise capacity (11.49 ± 0.22 vs 13.65 ± 0.19, p < 0.001), systolic BP (122.08 ± 1.33 vs 116.58 ± 1.17, P = 0.005), and diastolic BP (79.83 ± 0.84 vs 74.35 ± 0.74, p < 0.001). No significant between-group differences were observed in other variables.Conclusion: Both home-based and center-based CR improved exercise capacity; however, center-based CR achieved superior gains and better blood pressure control. Home-based CR may be a practical alternative when access to supervised programs is limited.Clinical trial registration: www.IRCT.iridentifier:IRCT20201028049181N1.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"811-818"},"PeriodicalIF":1.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148648504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic value of late gadolinium enhancement in peripartum cardiomyopathy: a systematic review and meta-analysis. 围产期心肌病晚期钆增强的预后价值：一项系统回顾和荟萃分析。

IF 1.1

Future cardiology Pub Date : 2026-08-01 Epub Date: 2026-07-24 DOI: 10.1080/14796678.2026.2708443

Apridya Nurhafizah, Wilbert Huang, Capella Kezia, Muhammad Irfan Fathoni, Rivera Adenia Firza Zahrani, Sean Anthony Samban, Susetyo Atmojo

{"title":"Prognostic value of late gadolinium enhancement in peripartum cardiomyopathy: a systematic review and meta-analysis.","authors":"Apridya Nurhafizah, Wilbert Huang, Capella Kezia, Muhammad Irfan Fathoni, Rivera Adenia Firza Zahrani, Sean Anthony Samban, Susetyo Atmojo","doi":"10.1080/14796678.2026.2708443","DOIUrl":"10.1080/14796678.2026.2708443","url":null,"abstract":"Background: Peripartum cardiomyopathy (PPCM) is a rare but life-threatening condition occurring during late pregnancy or the postpartum period. Although late gadolinium enhancement (LGE) has prognostic value in other cardiomyopathies, its role in PPCM remains unclear. This study aimed to evaluate the prognostic significance of LGE in PPCM.Methods: Three electronic databases were systematically searched to identify studies assessing the association between LGE and clinical outcomes in PPCM. Outcomes included reduced left ventricular ejection fraction (LVEF), arrhythmia, heart failure decompensation, device implantation, transplantation, and mortality. Pooled hazard ratios were calculated using the generic inverse variance method.Results: Eight cohort studies involving 227 patients were included. The mean age was 32.2 ± 6.6 years and mean LVEF was 30.5%. The pooled hazard ratio analysis revealed that LGE was significantly associated with poor outcomes (HR 1.34, CI 1.04-1.73 I2 = 52%, p = 0.02). Further analysis demonstrated that LGE was strongly linked to adverse clinical outcomes (HR 2.95, CI 1.62-5.37, I2 = 0%, p = 0.004), whereas no significant association was observed with persistently reduced LVEF (HR 1.11, CI 0.85-1.45, I2 = 14%, p = 0.45).Conclusion: LGE is associated with poor outcomes in PPCM and may provide complementary prognostic value for risk stratification.Protocol registration: www.crd.york.ac.uk/prospero identifier is CRD42024568502.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"885-892"},"PeriodicalIF":1.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148578195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Uric acid-to-lymphocyte ratio as a predictor of incident heart failure in community-dwelling older adults: an exploratory historical cohort study in primary care. 尿酸与淋巴细胞比值作为社区居住老年人心力衰竭事件的预测因子：一项初级保健的探索性历史队列研究

IF 1.1

Future cardiology Pub Date : 2026-08-01 Epub Date: 2026-07-31 DOI: 10.1080/14796678.2026.2713297

Abir Alsalahi Taha, Alejandro Sosa Jiménez, Juan Abreu González

{"title":"Uric acid-to-lymphocyte ratio as a predictor of incident heart failure in community-dwelling older adults: an exploratory historical cohort study in primary care.","authors":"Abir Alsalahi Taha, Alejandro Sosa Jiménez, Juan Abreu González","doi":"10.1080/14796678.2026.2713297","DOIUrl":"10.1080/14796678.2026.2713297","url":null,"abstract":"Background: The uric acid-to-lymphocyte ratio (UALR) is an inexpensive hemogram-derived index whose value for predicting incident heart failure (HF) in older primary care patients is unknown.Materials and methods: In a historical cohort of 310 community-dwelling adults aged 70-85 years followed for 5 years, baseline UALR was compared with the monocyte-to-lymphocyte ratio (MLR), systemic immune-inflammation index (SII), and platelet-to-lymphocyte ratio (PLR) as predictors of incident HF (n = 25, 8.1%), defined by WHO clinical criteria. Patients who died during follow-up were excluded by design, which may attenuate the observed association.Results: UALR showed the best individual discriminative performance (OR = 1.424, 95% CI: 1.117-1.815; AUC = 0.697) and, after Benjamini - Hochberg correction, was superior to PLR but statistically equivalent to MLR and SII. In nested models, the ratio retained a nominal signal over its components (likelihood ratio test p = 0.016), independent of renal function. Cox regression with bootstrap internal validation yielded a corrected Harrell's C of 0.843; log-rank by UALR tertiles p < 0.0001.Conclusions: In this exploratory cohort, UALR was associated with incident HF, comparable to MLR and SII and superior to PLR. These findings are hypothesis-generating; the limited event count, historical design, and absence of external validation preclude clinical application.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"841-849"},"PeriodicalIF":1.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148648547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spontaneous coronary artery dissection versus atherosclerotic myocardial infarction in young women: a propensity-matched cohort study. 年轻女性自发性冠状动脉剥离与动脉粥样硬化性心肌梗死：倾向匹配队列研究

IF 1.1

Future cardiology Pub Date : 2026-08-01 Epub Date: 2026-08-17 DOI: 10.1080/14796678.2026.2708502

Ali Awad, Nader Alwifati, David Echeverri, Qusai Al Qudah, Khaled Elnaggar, Laith Rhabneh, Joud Fahed, Jawad Basit, Mariam Chalhoub, M Chadi Alraies

{"title":"Spontaneous coronary artery dissection versus atherosclerotic myocardial infarction in young women: a propensity-matched cohort study.","authors":"Ali Awad, Nader Alwifati, David Echeverri, Qusai Al Qudah, Khaled Elnaggar, Laith Rhabneh, Joud Fahed, Jawad Basit, Mariam Chalhoub, M Chadi Alraies","doi":"10.1080/14796678.2026.2708502","DOIUrl":"10.1080/14796678.2026.2708502","url":null,"abstract":"Background: Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute myocardial infarction (AMI) in young women, yet long-term comparisons with atherosclerotic AMI are limited. We compared outcomes in women aged 18-55 years with these two conditions.Methods: Using the TriNetX research network, we conducted a retrospective cohort study of women aged 18-55 years with SCAD or atherosclerotic myocardial infaction(AMI). Cohorts were balanced by 1:1 propensity score matching, and outcomes assessed at 30 days, 1 year, and 3 years. Sensitivity analyses used age-only, Body Mass Index (BMI) only, and SCAD-without-acute-MI cohorts.Results: After matching, 1,297 patients were included per cohort. Thirty-day mortality was similar (1.2% vs 1.7%; HR 0.72, p = 0.33), but heart failure was less frequent in SCAD (HR 0.44, p = 0.001). SCAD remained associated with lower 1-year heart failure (HR 0.38, p < 0.001) and, at 3 years, lower mortality (HR 0.48, p = 0.002), stroke (HR 0.45, p = 0.012), heart failure (HR 0.33, p < 0.001), ventricular tachycardia (HR 0.48, p = 0.008), angina (HR 0.26, p < 0.001), and rehospitalization (HR 0.34, p < 0.001). Benefits persisted across all sensitivity analyses.Conclusions: Compared with atherosclerotic AMI, women with SCAD had more favorable intermediate- and long-term outcomes despite similar early mortality. These hypothesis-generating findings may warrant tailored management strategies that merit prospective evaluation.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"819-828"},"PeriodicalIF":1.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148764577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) in patients with prior chest radiation: a systematic review and meta-analysis of 11,572 patients. 经导管主动脉瓣置换术（TAVR）和外科主动脉瓣置换术（SAVR）对既往胸部放疗患者的比较：11,572例患者的系统回顾和荟萃分析。

IF 1.1

Future cardiology Pub Date : 2026-08-01 Epub Date: 2026-08-05 DOI: 10.1080/14796678.2026.2713341

Athina Ntoumaziou, Dimitrios Xenos, Marios Sagris, Achilles Chatziioannou, Miltiadis Krokidis, Andreas Tzoumas

{"title":"Comparison of transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) in patients with prior chest radiation: a systematic review and meta-analysis of 11,572 patients.","authors":"Athina Ntoumaziou, Dimitrios Xenos, Marios Sagris, Achilles Chatziioannou, Miltiadis Krokidis, Andreas Tzoumas","doi":"10.1080/14796678.2026.2713341","DOIUrl":"10.1080/14796678.2026.2713341","url":null,"abstract":"Background: Cardiac complications from prior oncologic therapies and radiation are being increasingly recognized and patients with symptomatic severe aortic valve disease and a history of prior chest radiation represent a high-risk group in which the best management approach has not yet been established.Methods: A systematic search of PubMed, Scopus, and Cochrane identified studies comparing outcomes of transcatheter aortic valve replacement (TAVR) vs surgical aortic valve replacement (SAVR) in patients with a history of prior chest radiation.Results: Nine studies comprising 11,572 patients were included in this meta-analysis. There were no significant differences between TAVR and SAVR in postoperative mortality (OR: 0.70; 95% CI 0.44-1.13, p = 0.147) or 1-year mortality (OR: 1.04; 95% CI 0.71-1.53, p = 0.84). TAVR was associated with significantly lower rate of postoperative major bleeding (OR: 0.38; 95%CI: 0.25-0.57, p < 0.01), acute kidney injury (AKI) (OR: 0.51; 95%CI: 0.27-0.97, p: 0.04), postoperative atrial fibrillation (OR: 0.20 95%CI: 0.16-0.24, p: <0.01) and respiratory complications (OR: 0.39; 95%CI: 0.24-0.63, p < 0.01) compared to SAVR. The incidence of postoperative permanent pacemaker insertion (OR: 2.27; 95%CI: 1.79-2.87, p < 0.01) and at least moderate aortic regurgitation (OR: 4.44 (95%CI: 2.93-6.73), p < 0.01) were higher among the patients undergoing TAVR.Conclusions: TAVR in patients with a history of prior radiation was associated with a lower risk for postoperative complications albeit at an increased risk for pacemaker insertion in the postoperative period compared to SAVR.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"865-874"},"PeriodicalIF":1.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148673524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Late aortic root pseudoaneurysm after pericardial patch reconstruction for bicuspid aortic valve endocarditis: a case report. 二尖瓣主动脉瓣心内膜炎心包补片重建后晚期主动脉根假性动脉瘤1例。

IF 1.1

Future cardiology Pub Date : 2026-08-01 Epub Date: 2026-08-06 DOI: 10.1080/14796678.2026.2713321

Reuben L Odai, Frank Kutilek, Laiba Sajjad, Anthony Alchaer, Hussam Farhoud

{"title":"Late aortic root pseudoaneurysm after pericardial patch reconstruction for bicuspid aortic valve endocarditis: a case report.","authors":"Reuben L Odai, Frank Kutilek, Laiba Sajjad, Anthony Alchaer, Hussam Farhoud","doi":"10.1080/14796678.2026.2713321","DOIUrl":"10.1080/14796678.2026.2713321","url":null,"abstract":"A 70-year-old male with bicuspid aortic valve developed oxacillin-sensitive Staphylococcus aureus bacteremia complicated by infective endocarditis, aortic root abscess, and embolic stroke. Initial management included aortic valve replacement with a bioprosthetic valve, aortic root reconstruction with bovine pericardial patch, and anterior mitral leaflet repair. Despite appropriate antimicrobial therapy, the patient developed recurrent symptoms three years later. Transesophageal echocardiography revealed severe aortic regurgitation and a large pseudoaneurysm resulting from dehiscence of the previous pericardial patch repair. The patient underwent successful repeat sternotomy with aortic root replacement using a valved conduit and reimplantation of coronary arteries. This case highlights the challenging nature of endocarditis involving the aortic root, particularly when complicated by abscess formation requiring patch reconstruction, and emphasizes the importance of long-term surveillance for pseudoaneurysm formation following such complex repairs.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"799-802"},"PeriodicalIF":1.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540169/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148684176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Plain language summary of how acoramidis affects the total number of heart problems over time in people with ATTR-CM: findings from the ATTRibute-CM study. acoramidis如何随时间影响ATTR-CM患者心脏问题的总数：ATTRibute-CM研究的发现。

IF 1.1

Future cardiology Pub Date : 2026-08-01 Epub Date: 2026-08-03 DOI: 10.1080/14796678.2026.2704342

Ahmad Masri, Daniel P Judge, Frederick L Ruberg, Julian D Gillmore, Justin L Grodin, Laura Obici, Mathew S Maurer, Marianna Fontana, Steen Hvitfeldt Poulsen, Peter van der Meer, Richard K Cheng, Sarah A M Cuddy, Amrut V Ambardekar, Kuangnan Xiong, Xiaofan Cao, Gillian Murtagh, Suresh Siddhanti, Adam Castaño, Jean-François Tamby, Jonathan C Fox, Kevin M Alexander, Ronald Witteles

引用次数: 0

Ventricular arrhythmias and mortality in chronic total coronary occlusion: PCI versus optimal medical therapy in patients with LVEF greater than 35. 慢性全冠状动脉闭塞的室性心律失常和死亡率：LVEF大于35的患者PCI与最佳药物治疗

IF 1.1

Future cardiology Pub Date : 2026-08-01 Epub Date: 2026-08-11 DOI: 10.1080/14796678.2026.2712108

Ahmad Jabri, Laith Alhuneafat, Omar Obeidat, Faris Haddadin, Mohammad Alqarqaz, Saima Karim, Aisha Siraj

{"title":"Ventricular arrhythmias and mortality in chronic total coronary occlusion: PCI versus optimal medical therapy in patients with LVEF greater than 35.","authors":"Ahmad Jabri, Laith Alhuneafat, Omar Obeidat, Faris Haddadin, Mohammad Alqarqaz, Saima Karim, Aisha Siraj","doi":"10.1080/14796678.2026.2712108","DOIUrl":"10.1080/14796678.2026.2712108","url":null,"abstract":"Background: Ventricular arrhythmia (VA) risk in patients with chronic total coronary occlusion (CTO) without advanced left ventricular (LV) dysfunction is poorly defined, and whether revascularization reduces VA compared with optimal medical therapy (OMT) remains unknown.Methods: We conducted a single-center retrospective cohort study of 100 patients with angiographically confirmed CTO, LVEF > 35%, and no coronary artery bypass surgery after diagnosis between January 2010 and January 2019. CTO percutaneous coronary intervention (CTO-PCI) was performed in 44 patients, while 56 received OMT. Primary outcomes were VA and all-cause mortality at study end. Secondary cardiovascular outcomes were assessed. Kaplan - Meier methods were used for VA and mortality analyses, performed with STATA 15 and RStudio.Results: Mean age was 59.9 ± 13.1 years, BMI was 31.8 ± 7.4 kg/m2, 66% were male, 64% White, and 23% Black. Baseline characteristics, including LVEF, CTO number and location, and use of antiarrhythmics, beta-blockers, and statins, were similar between groups. During 4.1 ± 2.5 years of follow-up, OMT was associated with higher VA (21.4% vs 2.3%, p = 0.01) and mortality (37.5% vs 15.9%, p = 0.03) than successful CTO-PCI.Conclusions: Among CTO patients with LVEF > 35%, VA and mortality were frequent, particularly with OMT, supporting prospective studies to confirm benefit and refine patient selection for revascularization strategies.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"829-839"},"PeriodicalIF":1.1,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148705964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feasibility of pulsed field ablation for ventricular arrhythmia: a systematic review. 脉冲场消融治疗室性心律失常的可行性：一项系统综述。

IF 1.1

Future cardiology Pub Date : 2026-07-01 Epub Date: 2026-07-11 DOI: 10.1080/14796678.2026.2699788

Irnizarifka Irnizarifka, Christopher Daniel Tristan, Enrico Ananda Budiono, Matthew Aldo Wijayanto, Immanuel Soni Tanudjaya, Raymond Pranata, Mohammad Iqbal

{"title":"Feasibility of pulsed field ablation for ventricular arrhythmia: a systematic review.","authors":"Irnizarifka Irnizarifka, Christopher Daniel Tristan, Enrico Ananda Budiono, Matthew Aldo Wijayanto, Immanuel Soni Tanudjaya, Raymond Pranata, Mohammad Iqbal","doi":"10.1080/14796678.2026.2699788","DOIUrl":"10.1080/14796678.2026.2699788","url":null,"abstract":"Introduction: Beyond its efficacy on atrial fibrillation, pulsed field ablation (PFA) presents potential advantages in ventricular arrhythmia. This study sought to investigate the feasibility of PFA for ventricular tachycardia (VT) and premature ventricular complexes (PVC).Method: A systematic search (Scopus, PubMed, and Science Direct) with citation searching was performed on 9 January 2026. Studies evaluating the feasibility of PFA in VT and PVC were included.Result: This study included seven studies (74 patients with VT and 86 with PVC). Pooled acute procedural success rate in VT was 0.92 (95% CI: 0.86-0.99) and in the PVC was 0.93 (95% CI: 0.86-1.00). During follow-up, VT recurrence rates ranged from 20% to 54%. PVC ablation demonstrated a significant burden reduction (MD: 86.54%; 95% CI: 59.21-113.86; p = 0.005) with long-term success rates ranging from 50% to 85%. Safety evaluation demonstrated satisfactory outcomes, with major adverse cardiovascular events (MACE) during follow-up occurring in four patients with high-risk comorbidity. Major adverse events (AEs) occurred in 11 patients and were preventable; minor AEs consisted solely of vascular access site AEs.Conclusion: PFA was feasible for VT and PVC ablation. Larger long-term studies and standardized protocol were urgently necessary to ensure efficacy with minimal AEs.Protocol registration: www.crd.york.ac.uk/prospero identifier is CRD420251272352.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"773-785"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540101/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148420503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0