Acute myocardial infarction treatment delay in South Asia: a systematic review and meta-analysis.

IF 1 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Future cardiology Pub Date : 2025-08-14 DOI:10.1080/14796678.2025.2541525

Deepthi Ramamurthy, Meely Panda, Manjula Rangappa, Suthanthira Kannan, Rashmi Kundapur, Swetha Rajeshwari, Padmavathi Subbiah, Pradeep Aggarwal, Sumit Aggarwal

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引用次数: 0

Abstract

Background: Acute Myocardial Infarction (AMI) necessitates timely treatment to improve outcomes. Identifying treatment delays across different South Asian countries can aid in formulating policies to reduce these delays. Objectives: To estimate the average treatment delay in AMI patients in South Asia and identify contributing factors.

Methods: Using the CoCoPop framework (Condition, Context, Population), studies were reviewed on AMI treatment delays in South Asia from 2000 to 2022. Databases searched included PubMed Central, Embase and Google Scholar. Eligible studies were cross-sectional and analytical that reported exact delay times, excluding knowledge, attitude, practice studies, narrative reviews, and case reports.

Results: The search yielded 2954 records, with 42 studies meeting the inclusion criteria. The pooled median prehospital delay was 531 minutes (95% CI: 366-769 minutes). The pooled mean door-to-ECG time was 9.18 minutes (95% CI: 2.52-15.84 minutes). The door-to-needle and door to balloon time among STEMI patients were 37.95 (95% CI: 30.11-45.78 minutes) minutes and 62.92 minutes (95% CI: 45.28-80.56 minutes), respectively with significant heterogeneity. Factors associated with delays included old age, female gender, low literacy, ignorance, financial constraints, and rural location.

Conclusion: Significant treatment delays for AMI patients in South Asia are identified, with socio-economic and logistical barriers contributing to these delays.

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南亚急性心肌梗死治疗延迟：系统回顾和荟萃分析。

背景：急性心肌梗死（AMI）需要及时治疗以改善预后。确定不同南亚国家的治疗延误有助于制定减少这些延误的政策。目的：估计南亚AMI患者的平均治疗延迟，并确定影响因素。方法：采用CoCoPop框架（条件、背景、人口），回顾2000年至2022年南亚AMI治疗延误的研究。检索的数据库包括PubMed Central、Embase和谷歌Scholar。符合条件的研究是横断面和分析性的，报告准确的延迟时间，排除知识、态度、实践研究、叙述性评论和病例报告。结果：检索到2954条记录，有42项研究符合纳入标准。院前延迟的中位数为531分钟（95% CI: 366-769分钟）。合并平均门到心电图时间为9.18分钟（95% CI: 2.52-15.84分钟）。STEMI患者从门到针的时间为37.95分钟（95% CI: 30.11 ~ 45.78分钟），从门到球囊的时间为62.92分钟（95% CI: 45.28 ~ 80.56分钟），异质性显著。与延迟相关的因素包括老年、女性、低识字率、无知、经济限制和农村地区。结论：南亚AMI患者的严重治疗延误被确定，社会经济和后勤障碍导致这些延误。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Future cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

2.80

自引率

5.90%

发文量

期刊介绍： Research advances have contributed to improved outcomes across all specialties, but the rate of advancement in cardiology has been exceptional. Concurrently, the population of patients with cardiac conditions continues to grow and greater public awareness has increased patients" expectations of new drugs and devices. Future Cardiology (ISSN 1479-6678) reflects this new era of cardiology and highlights the new molecular approach to advancing cardiovascular therapy. Coverage will also reflect the major technological advances in bioengineering in cardiology in terms of advanced and robust devices, miniaturization, imaging, system modeling and information management issues.