Future cardiology最新文献

Cardiomyopathy genetic testing: insights into demographics, counseling, and cascade screening.

IF 1.6

Future cardiology Pub Date : 2025-04-09 DOI: 10.1080/14796678.2025.2484128

Quan M Bui, Elizabeth Silver, Alessia Argiro, Sarah Murray, Lauren Korty, Jorge Silva Enciso, Marcus A Urey, Neil C Chi, Kimberly N Hong, Eric D Adler

{"title":"Cardiomyopathy genetic testing: insights into demographics, counseling, and cascade screening.","authors":"Quan M Bui, Elizabeth Silver, Alessia Argiro, Sarah Murray, Lauren Korty, Jorge Silva Enciso, Marcus A Urey, Neil C Chi, Kimberly N Hong, Eric D Adler","doi":"10.1080/14796678.2025.2484128","DOIUrl":"https://doi.org/10.1080/14796678.2025.2484128","url":null,"abstract":"Background: Genetic testing (GT) is clinically indicated for patients with suspected inherited cardiomyopathy (CM) but is underutilized.Methods: This single-center study included patients with CM who underwent outpatient GT from 2018 to 2023. Data were collected from the medical record.Results: A total of 306 patients were included, with a mean age of 62 years and were predominantly male (63%) and White (59%). Heart failure (92%) cardiologists were most likely to order testing, followed by general cardiology (5%) providers at tertiary hospital clinics (89%). The most common phenotypes were hypertrophic (30%), amyloid (29%) and dilated (21%). There were 17% of patients who had a positive test and 53% of patients who had a variant of uncertain significance. Patients with a positive family history had a significantly higher positive yield compared to those without (p < 0.01). Genetic counselors were underutilized (17%). For patients who had a positive test result, only 40% had cascade screening.Conclusions: Outpatient GT for CM was primarily ordered by heart failure cardiologists in tertiary hospital clinics. Cascade screening was low, which may reflect the limited use of genetic counselors. Further research is needed to understand implementation barriers to GT.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"1-6"},"PeriodicalIF":1.6,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current and future landscape of heart failure management: understanding the present, unraveling the future.

IF 1.6

Future cardiology Pub Date : 2025-04-09 DOI: 10.1080/14796678.2025.2490403

Cristina Madaudo, Daniel Bromage, Antonio Cannata

引用次数: 0

Risk of cardiovascular disease in people with narcolepsy: a plain language summary of publication.

IF 1.6

Future cardiology Pub Date : 2025-04-02 DOI: 10.1080/14796678.2025.2482383

Jed Black, Rorey Smith, Elizabeth C Dabrowski, Ben Taylor, Virend K Somers

引用次数: 0

Real-world evidence comparing oral anticoagulants for NVAF in Europe: a systematic review and network meta-analysis.

IF 1.6

Future cardiology Pub Date : 2025-04-02 DOI: 10.1080/14796678.2025.2484119

Allie Cichewicz, Shantanu Jawla, Priccila Zuchinali, Morodoluwa Akin-Fajiye, Daniela Massierer, Italo Porto, Xavier Garcia-Moll

{"title":"Real-world evidence comparing oral anticoagulants for NVAF in Europe: a systematic review and network meta-analysis.","authors":"Allie Cichewicz, Shantanu Jawla, Priccila Zuchinali, Morodoluwa Akin-Fajiye, Daniela Massierer, Italo Porto, Xavier Garcia-Moll","doi":"10.1080/14796678.2025.2484119","DOIUrl":"https://doi.org/10.1080/14796678.2025.2484119","url":null,"abstract":"Aim: Atrial fibrillation is the most commonly sustained cardiac arrhythmia, increasing the risk of stroke and systemic embolic events. This systematic review and network meta-analysis (NMA) aimed to compare real-world evidence (RWE) on the effectiveness and safety of edoxaban with other direct oral anticoagulants (DOACs) and vitamin K antagonists (VKAs) in patients with non-valvular atrial fibrillation (NVAF) in Europe.Materials & methods: Searches from January 2013 to December 2022 identified comparative observational studies assessing effectiveness/safety outcomes in patients with NVAF. Bayesian NMA estimated comparative effectiveness/safety of edoxaban with other DOACs and VKAs.Results: The review identified 57 studies analyzing data from 24 unique databases; 33 studies were included in the base-case analyses. DOACs showed benefit over VKAs for most outcomes, of which major bleeding and all-cause mortality were most commonly reported. Edoxaban demonstrated a comparable effectiveness/safety profile to other DOACs and significantly reduced risk of major bleeding (hazard ratio [95% credible interval]: 0.67 [0.54, 0.84]) and intracranial hemorrhage (0.69 [0.51, 0.94]) versus rivaroxaban.Conclusion: This NMA provides valuable insights into the real-world effectiveness and safety of DOACs and VKAs in Europe, supporting clinical decision-making and adding to the existing evidence base from clinical trials.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"1-20"},"PeriodicalIF":1.6,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143763716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of obesity-related HFpEF: a STEP closer to the SUMMIT.

IF 1.6

Future cardiology Pub Date : 2025-04-01 Epub Date: 2025-03-07 DOI: 10.1080/14796678.2025.2477429

Paschalis Karakasis, Nikolaos Fragakis, Ieva Ruža, Panagiotis Stachteas, Dimitrios Patoulias

引用次数: 0

Partial obesity paradox regarding mortality in patients hospitalized with diastolic or systolic heart failure.

IF 1.6

Future cardiology Pub Date : 2025-04-01 Epub Date: 2025-03-10 DOI: 10.1080/14796678.2025.2477421

Mohammad Reza Movahed, Austin Mineer, Mehrtash Hashemzadeh

{"title":"Partial obesity paradox regarding mortality in patients hospitalized with diastolic or systolic heart failure.","authors":"Mohammad Reza Movahed, Austin Mineer, Mehrtash Hashemzadeh","doi":"10.1080/14796678.2025.2477421","DOIUrl":"10.1080/14796678.2025.2477421","url":null,"abstract":"Introduction: A phenomenon known as the obesity paradox has been reported in patients with heart failure (HF). The goal of this study is to characterize this observation in systolic (SHF) and diastolic (DHF) HF.Methods and results: We used the National Inpatient Sample (NIS) database for 2016-2020. We evaluated mortality based on body weight. A total of 7,364,023 with SHF and 10,064,223 with DHF were found in the NIS database. All-cause inpatient mortality was lowest in overweight followed by obesity and morbid obesity, whereas mortality was highest in cachexia for SHF and DHF (mortality: overweight 2.56%, obese 3.12%, morbidly obese 3.70%, normal weight 5.60%, and cachexia 15.22%; p < 0.001) and DHF patients (mortality: overweight 2.08%, obese 2.43%, morbidly obese 2.93%, normal weight 4.58%, and cachexia 14.25%; p < 0.001). This relationship remains similar after multivariate analysis (SHF patients: overweight OR: 0.49 (0.41-0.58), obesity OR: 0.64 (0.62-0.66), morbid obesity OR: 0.85 (0.83-0.88), and cachexia OR: 2.78 (2.67-2.90); p < 0.001; DHF patients: overweight OR: 0.47 (0.40-0.56), obesity OR: 0.61 (0.59-0.63), morbid obesity OR: 0.83 (0.81-0.85), and cachexia OR: 3.09 (2.96-3.23); p < 0.001).Conclusions: All-cause inpatient mortality in SHF and DHF is lowest in overweight populations followed by obese and morbidly obese populations, whereas cachexia has the highest mortality.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"283-290"},"PeriodicalIF":1.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143585373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A clinician's guide to cardiovascular MRI referrals: a practical guide of ESC recommendations.

IF 1.6

Future cardiology Pub Date : 2025-04-01 DOI: 10.1080/14796678.2025.2485787

Nicola Ciocca, Henri Lu, Georgios Tzimas, Niccolò Maurizi, Ioannis Skalidis, Mark Colin Gissler, Pierre Monney, Christoph Gräni, Yin Ge, Panagiotis Antiochos

引用次数: 0

Diagnosing and treating stable angina: a contemporary approach for practicing physicians.

IF 1.6

Future cardiology Pub Date : 2025-04-01 Epub Date: 2025-03-21 DOI: 10.1080/14796678.2025.2479970

Athanasios J Manolis, Peter Collins, José López-Sendón

{"title":"Diagnosing and treating stable angina: a contemporary approach for practicing physicians.","authors":"Athanasios J Manolis, Peter Collins, José López-Sendón","doi":"10.1080/14796678.2025.2479970","DOIUrl":"10.1080/14796678.2025.2479970","url":null,"abstract":"Longer life expectancy and advancements in coronary artery disease management have improved life expectancy and survival, increasing the prevalence of chronic coronary syndromes (CCS). Angina is a common symptom in patients with CCS but remains underdiagnosed and undertreated. Contemporary guidelines provide detailed information on diagnosing and treating angina based on evidence and expert consensus; however, their extensive nature may hinder uptake by non-specialists. This review presents a practical approach to diagnosing stable angina, followed by the three pillars of CCS management: 1) healthy lifestyle including appropriate exercise, diet, and avoiding toxic habits; 2) optimal medical therapy, including treatment recommended to prevent cardiovascular events and drugs for the control of myocardial ischemia and angina tailored to the patient's comorbidities; and 3) myocardial revascularization when indicated. This approach may be useful for practicing physicians but is not intended to substitute more detailed and authoritative documents. Checklists are proposed to help focus patient-physician interactions and make follow-up visits more efficient. This approach seeks to increase the proportion of correct angina diagnoses and patients receiving evidence-based treatments, emphasizing the importance of patient education, managing residual angina, and reducing cardiovascular risk. We include reference to the recently published 2024 ESC guidelines on chronic coronary syndromes.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"291-303"},"PeriodicalIF":1.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Through the gap: a case series on managing Type B aortic dissection with multiple lumens and tears.

IF 1.6

Future cardiology Pub Date : 2025-04-01 Epub Date: 2025-03-21 DOI: 10.1080/14796678.2025.2482369

Sriram Sunil Kumar, Sanjana Nagraj, Nathaniel Abittan, Ayelet Beilin, Sharanya Kaushik, Sophie Madlena Starosta, Mark Guelfguat

{"title":"Through the gap: a case series on managing Type B aortic dissection with multiple lumens and tears.","authors":"Sriram Sunil Kumar, Sanjana Nagraj, Nathaniel Abittan, Ayelet Beilin, Sharanya Kaushik, Sophie Madlena Starosta, Mark Guelfguat","doi":"10.1080/14796678.2025.2482369","DOIUrl":"10.1080/14796678.2025.2482369","url":null,"abstract":"Aortic dissections are classified as Stanford Type A and B based on site of intimal dissection. Management of Type B dissections is guided by risk stratification. Complicated and high-risk Type B aortic dissections are managed either using endovascular or open surgical repair. Uncomplicated Type B dissections are managed medically. The role of the patency of the false lumen and the presence of reentry tears in the dissecting membrane are still contested. Here, we describe two cases of descending aortic dissections with varying anatomical features in the setting of cocaine use and uncontrolled hypertension. The first case uniquely had a triple lumen dissection with two true lumens, while the second case had two distal tears. Both patients initially had signs of reduced end organ perfusion that resolved with control of comorbid conditions. After multidisciplinary discussions, the decision was made to continue with anti-impulse treatment. Due to the radiological and biochemical absence of evidence of end organ injury even while visceral organs were supplied by the false lumen, our multidisciplinary team preferred conservative management with anti-impulse therapy. This serves as a demonstration of individualized management of Type B aortic dissection in patients with multiple comorbidities using carefully analyzed radiographic and biochemical evidence.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"275-282"},"PeriodicalIF":1.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

OCT-Guided covered stent implantation for acquired coronary aneurysm after bioresorbable vascular scaffold: case report.

IF 1.6

Future cardiology Pub Date : 2025-04-01 Epub Date: 2025-03-28 DOI: 10.1080/14796678.2025.2481731

Ting-Yu Lin, Young-Fong Siew, Tse-Min Lu

{"title":"OCT-Guided covered stent implantation for acquired coronary aneurysm after bioresorbable vascular scaffold: case report.","authors":"Ting-Yu Lin, Young-Fong Siew, Tse-Min Lu","doi":"10.1080/14796678.2025.2481731","DOIUrl":"10.1080/14796678.2025.2481731","url":null,"abstract":"Coronary artery aneurysm (CAA) formation following bioresorbable vascular scaffold (BVS) implantation is a rare but serious complication with no clear treatment guidelines. We report the case of a 56-year-old man with coronary artery disease (CAD) and a chronic total occlusion (CTO) in the left anterior descending artery (LAD) underwent full revascularization with BVS in 2016. Seven years later, he experienced recurrent angina, and angiography revealed 80% stenosis in the proximal LAD and a large coronary aneurysm in the middle LAD. Optical coherence tomography (OCT) confirmed a 5.88 mm aneurysm, which was treated with a PK Papyrus covered stent, while the proximal LAD stenosis was addressed with a Resolute Onyx drug-eluting stent (DES). After six months of standard dual antiplatelet therapy (DAPT) followed by three months of single antiplatelet therapy (SAPT), the patient developed in-stent restenosis (ISR) in the covered stent. This was successfully treated with high-pressure balloon angioplasty and a drug-eluting balloon (DEB). At the nine-month follow-up, the patient remained symptom-free. This case highlights the utility of OCT in evaluating CAAs and guiding covered stent deployment, while prolonged DAPT may help reduce the risk of very late stent thrombosis and future ischemic events, though further studies are needed.","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"269-273"},"PeriodicalIF":1.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143742769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0