Future cardiologyPub Date : 2026-07-01Epub Date: 2026-07-23DOI: 10.1080/14796678.2026.2704403
Ahmed Abdalwahab, Abdalazeem Ibrahem, Mohamed Farag
{"title":"Optimizing TAVI strategy: balancing predilatation benefits and direct implantation efficiency.","authors":"Ahmed Abdalwahab, Abdalazeem Ibrahem, Mohamed Farag","doi":"10.1080/14796678.2026.2704403","DOIUrl":"10.1080/14796678.2026.2704403","url":null,"abstract":"<p><p>Balloon aortic valvuloplasty (BAV) has historically been considered an integral step during transcatheter aortic valve implantation (TAVI), facilitating valve crossing and expansion, particularly in early-generation devices. However, advances in valve technology, delivery systems, and imaging have prompted a shift toward direct TAVI without routine predilatation. Contemporary evidence from randomized trials, large registries, and meta-analyses demonstrates that direct TAVI is feasible and safe in anatomically favorable cases, with comparable device success and early clinical outcomes to BAV-assisted implantation. Nonetheless, predilatation remains valuable in selected patients with complex anatomy, including severe leaflet calcification, high transvalvular gradients, bicuspid morphology, horizontal aorta, or challenging valve crossing. Predilatation may further improve procedural control, optimize valve expansion, and reduce residual paravalvular leakage, particularly with self-expandable valves and platforms with lower intrinsic opening force. Conversely, routine BAV may increase procedural complexity, radiation and contrast exposure, and embolic risk. Overall, current evidence supports a selective, anatomy-driven approach to predilatation, balancing procedural efficiency with optimal valve deployment and safety. This review critically examines the evolving role of BAV in contemporary TAVI practice.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"753-760"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148561706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2026-07-01Epub Date: 2026-07-06DOI: 10.1080/14796678.2026.2692606
Omar Obeidat, Moh'd Daise, Qusai Alqudah, Mohammad Tarawneh, Hashim Al-Ani, Laith Alhuneafat, Ali Obeidat, Mohamed F Ismail, Abedallah Obeidat, Saeed Abughazaleh, Maria Obeidat, Jowan Al-Nusair, Ann Tong
{"title":"Breast cancer and coronary artery disease: insights from a national inpatient sample analysis.","authors":"Omar Obeidat, Moh'd Daise, Qusai Alqudah, Mohammad Tarawneh, Hashim Al-Ani, Laith Alhuneafat, Ali Obeidat, Mohamed F Ismail, Abedallah Obeidat, Saeed Abughazaleh, Maria Obeidat, Jowan Al-Nusair, Ann Tong","doi":"10.1080/14796678.2026.2692606","DOIUrl":"10.1080/14796678.2026.2692606","url":null,"abstract":"<p><strong>Background: </strong>The association between breast cancer and coronary artery disease (CAD) remains important because of shared cardiovascular risk factors, potential cardiotoxic effects of cancer therapy, and the growing population of breast cancer survivors.</p><p><strong>Objective: </strong>To evaluate whether women with active or prior breast cancer have higher odds of CAD-related hospitalization using a nationally representative inpatient database.</p><p><strong>Methods: </strong>We conducted a retrospective analysis of the 2016-2019 National Inpatient Sample. Adult women aged 18 years or older with active or prior breast cancer were compared with women without breast cancer. The study included 589,940 unweighted breast cancer hospitalizations, representing 2,949,699 weighted hospitalizations, matched to an equal number of controls. Propensity score matching and multivariable logistic regression were used to adjust for demographic and clinical confounders, including hypertension, diabetes, chronic kidney disease, smoking, obesity, dyslipidemia, and prior myocardial infarction.</p><p><strong>Results: </strong>Breast cancer was not associated with increased odds of CAD-related hospitalization. In the unmatched cohort, breast cancer was associated with lower odds of CAD hospitalization (OR 0.84; 95% CI 0.84-0.85), attenuating after matching (OR 0.99; 95% CI 0.98-0.99). Lower odds were also observed for STEMI and NSTEMI hospitalizations.</p><p><strong>Conclusion: </strong>Breast cancer was not associated with increased odds of CAD-related hospitalization.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"717-725"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148396274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cardio-oncology awareness: a multidisciplinary survey among trainees and practicing professionals at multidisciplinary settings.","authors":"Shagun Misra, Shruti Bansal, Punita Lal, Rupali Khanna, Aditya Kapoor, Shaleen Kumar","doi":"10.1080/14796678.2026.2692601","DOIUrl":"10.1080/14796678.2026.2692601","url":null,"abstract":"<p><strong>Aim: </strong>To assess the knowledge of healthcare professionals regarding cardiac complications of cancer treatments and their perspectives on cardio-oncology.</p><p><strong>Materials and methods: </strong>A web-based survey, adapted from the Ottawa Hospital Research Institute's questionnaire, was designed with 45 questions across seven sections, modified to local requirements. It was circulated among cardiologists, radiation oncologists, and medical oncologists practicing or training in multidisciplinary setups and academic centers. The survey explored respondents' understanding of cardio-oncology, awareness of cardiac complications of cancer treatment, availability of institutional services, and current practices. Descriptive statistics were used for analysis.</p><p><strong>Results: </strong>Fifty-six professionals responded, including 13 cardiologists, 31 radiation oncologists, and 12 medical oncologists. Of these, 31 (46.4%) were trainees, while only 1.8% reported formal training in cardio-oncology; 19.6% indicated availability of institutional training programs. Most (90%) recognized cardio-oncology as a field for identifying treatment-related side effects and referral to cardiologists, while 72% acknowledged its role in follow-up and 67.3% emphasized patient education. Nearly 70% believed cardio-oncology services could improve prognosis. Awareness of international guidelines was limited (38.2%), and no institution reported a structured program. Lack of infrastructure (55.4%) and limited interest (48.2%) were major barriers.</p><p><strong>Conclusion: </strong>The survey underscores significant gaps in training, awareness, and structured program in cardio-oncology.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"727-736"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540082/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148316792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2026-07-01Epub Date: 2026-08-25DOI: 10.1080/14796678.2026.2699728
Robert J Henning, Murray Shames
{"title":"The diagnosis and current treatment of chronic lower extremity arterial disease.","authors":"Robert J Henning, Murray Shames","doi":"10.1080/14796678.2026.2699728","DOIUrl":"10.1080/14796678.2026.2699728","url":null,"abstract":"<p><p>Chronic lower extremity arterial disease (PAD) can be categorized into three subsets: Asymptomatic PAD, Chronic Symptomatic PAD, and Chronic Limb Threatening Ischemia (CLTI). Symptoms, signs and treatment of patients in each category are presented. Ankle Brachial Pressure index and Doppler ultrasound should be measured and individuals with chronic symptomatic PAD and CLTI should undergo computed tomographic angiography (CTA), magnetic resonance angiography (MRA), or contrast peripheral vascular angiography for arterial revascularization evaluation. Medical therapy is initial treatment for asymptomatic and symptomatic chronic PAD and CLTI and should include a statin, antihypertensive medications, antiplatelet and antithrombotic therapy, and management of diabetes. American and European Society of Cardiology guidelines for CLTI with endovascular or surgical arterial revascularization are reviewed. Guidelines provide a Class 1 (strong) recommendation for endovascular therapy for patients with symptomatic claudication with hemodynamically significant aortoiliac or femoral popliteal disease who fail medical therapy and a structured exercise program. A Class 2 recommendation (i.e. reasonable) is given to surgical revascularization if preoperative risk is acceptable, technical factors suggest specific advantages over endovascular procedures, and an autologous saphenous vein is available for grafting. Rivaroxaban + Aspirin or a purinergic receptor P2Y G-protein coupled inhibitor + ASA and an exercise program are recommended for patients with chronic PAD.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"737-752"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148812647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2026-07-01Epub Date: 2026-06-22DOI: 10.1080/14796678.2026.2689050
Abdullah Bin Rashid, Eman Aslam, Isha Ashraf, Tehreem Mubeen, Amen Mubeen, Hamna Zakriya, Maryam Amjad
{"title":"Wearable devices for atrial fibrillation: diagnostic and screening roles of ECG and PPG-A systematic review.","authors":"Abdullah Bin Rashid, Eman Aslam, Isha Ashraf, Tehreem Mubeen, Amen Mubeen, Hamna Zakriya, Maryam Amjad","doi":"10.1080/14796678.2026.2689050","DOIUrl":"10.1080/14796678.2026.2689050","url":null,"abstract":"<p><strong>Objective: </strong>Atrial fibrillation (AF) is a major predictor of heart failure, stroke, and mortality. Traditional Holter monitors and event recorders are limited by short recording times. Wearable electrocardiographic (ECG) and photoplethysmographic (PPG) devices enable continuous monitoring and large-scale AF screening. This review assesses their diagnostic performance, clinical usefulness, and implementation challenges.</p><p><strong>Methods: </strong>Following PRISMA guidelines, PubMed, Embase, and Web of Science were searched for studies from 2010-2025. Included studies had ≥30 participants and reported AF detection accuracy or clinical outcomes. Studies evaluating PPG devices required ECG verification as the reference standard.</p><p><strong>Results: </strong>Wearable ECG patches showed high sensitivity (92-98%) and specificity (85-97%) and detected more AF episodes than short-duration Holter monitoring. PPG-based smartwatches demonstrated moderate-to-high accuracy in irregular pulse detection, further improved by AI-assisted algorithms. Limitations included motion artifacts, false positives, adherence issues, clinician data burden, and limited evidence for stroke prevention.</p><p><strong>Conclusion: </strong>Wearable ECG devices are reliable for clinical AF detection. PPG-based devices are best used for screening, with subsequent ECG confirmation according to international AF management guidelines.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"761-772"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540091/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148301607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2026-07-01Epub Date: 2026-06-28DOI: 10.1080/14796678.2026.2691823
Asal Yadollahi, Faeze Keihanian, Zahra Oskoueian, Vafa Baradaran Rahimi
{"title":"Mitral valve dysplasia associated with left ventricular non-compaction cardiomyopathy and papillary muscle hypertrophy: a case report.","authors":"Asal Yadollahi, Faeze Keihanian, Zahra Oskoueian, Vafa Baradaran Rahimi","doi":"10.1080/14796678.2026.2691823","DOIUrl":"10.1080/14796678.2026.2691823","url":null,"abstract":"<p><p>Mitral valve dysplasia is a rare congenital etiology of primary mitral valve regurgitation. It can cause severe chronic mitral regurgitation, which may eventually lead to left atrial and ventricular dilation and dysfunction. Left ventricular non-compaction is a relatively rare cardiomyopathy that overlaps with hypertrophic and dilated cardiomyopathy. It can also lead to left or right ventricular dysfunction and failure. Papillary muscle hypertrophy may be a subtype of, or an early expression of, hypertrophic cardiomyopathy. Herein, we present a 42-year-old woman with a rare coexistence of mitral valve dysplasia, non-compaction left ventricular cardiomyopathy, and papillary muscle hypertrophy.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"689-693"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540105/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148344916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2026-07-01Epub Date: 2026-08-05DOI: 10.1080/14796678.2026.2702094
Daniel P Judge, Kevin M Alexander, Francesco Cappelli, Marianna Fontana, Pablo Garcia-Pavia, Martha Grogan, Mazen Hanna, Ahmad Masri, Laura Obici, Prem Soman, Xiaofan Cao, Ted Lystig, Jean-François Tamby, Suresh Siddhanti, Adam Castaño, Leonid Katz, Jonathan C Fox, Kenneth W Mahaffey, Julian D Gillmore
{"title":"Effect of acoramidis on risk of death and heart problem-related hospitalizations in people with transthyretin amyloid cardiomyopathy: a plain language summary.","authors":"Daniel P Judge, Kevin M Alexander, Francesco Cappelli, Marianna Fontana, Pablo Garcia-Pavia, Martha Grogan, Mazen Hanna, Ahmad Masri, Laura Obici, Prem Soman, Xiaofan Cao, Ted Lystig, Jean-François Tamby, Suresh Siddhanti, Adam Castaño, Leonid Katz, Jonathan C Fox, Kenneth W Mahaffey, Julian D Gillmore","doi":"10.1080/14796678.2026.2702094","DOIUrl":"10.1080/14796678.2026.2702094","url":null,"abstract":"","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"673-682"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540129/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148673515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2026-07-01Epub Date: 2026-07-13DOI: 10.1080/14796678.2026.2701251
Idan Bergman, Amos Levi, Guy Witberg, Yeela Talmor-Barkan, Aviad Rotholz, Pablo Codner, Yaron Shapira, Ran Kornowski, Leor Perl
{"title":"Evaluating the UNICA system for the treatment of severe tricuspid regurgitation.","authors":"Idan Bergman, Amos Levi, Guy Witberg, Yeela Talmor-Barkan, Aviad Rotholz, Pablo Codner, Yaron Shapira, Ran Kornowski, Leor Perl","doi":"10.1080/14796678.2026.2701251","DOIUrl":"10.1080/14796678.2026.2701251","url":null,"abstract":"<p><p>Despite significant advances in transcatheter tricuspid valve repair and replacement (TTVR), a substantial proportion of patients with severe tricuspid regurgitation (TR) remain ineligible for currently available therapies due to anatomical constraints, advanced disease, or prohibitive procedural risk. Heterotopic valve implantation strategies, in which prosthetic valves are positioned outside the native tricuspid annulus, have emerged as alternative approaches for this challenging population. The UNICA system represents a novel single-stent, double valve heterotopic platform designed for patients with symptomatic severe TR who are unsuitable for surgical or transcatheter annular interventions. Early clinical experience suggests high technical success, short procedural times, favorable short-term safety, and meaningful improvements in functional status and quality of life. Mechanistically, the system offers potential advantages over existing TTVR devices by bypassing complex annular anatomy and simplifying procedural execution. Nevertheless, further prospective data is required to define long-term durability, optimal patient selection, and comparative effectiveness.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"683-688"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148436237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2026-07-01Epub Date: 2026-06-18DOI: 10.1080/14796678.2026.2689421
Tan Duy Nguyen, Mai Thi Tuyet Tran, Hanh Ngoc Huynh, Cuong Thao Lam
{"title":"Endovascular revascularisation of lower-extremity peripheral arterial disease: technical and clinical outcomes in a Vietnamese single-center prospective cohort study.","authors":"Tan Duy Nguyen, Mai Thi Tuyet Tran, Hanh Ngoc Huynh, Cuong Thao Lam","doi":"10.1080/14796678.2026.2689421","DOIUrl":"10.1080/14796678.2026.2689421","url":null,"abstract":"<p><strong>Aims: </strong>To characterize lesion distribution, procedural strategy, and short-term outcomes after endovascular revascularisation for symptomatic lower-extremity peripheral arterial disease (PAD) in routine Vietnamese practice.</p><p><strong>Materials and methods: </strong>This prospective observational cohort included 336 consecutive patients with symptomatic lower-extremity PAD who underwent endovascular revascularisation at a Vietnamese tertiary center from January 2019 to January 2025. Lesions were classified across aorto-iliac, femoropopliteal, and infrapopliteal segments using a TASC-based framework. Outcomes were assessed post-procedure and at 30 days, 3 months, and 6 months.</p><p><strong>Results: </strong>Two-level disease was the most common anatomical pattern (47.3%), followed by three-level disease (36.0%). Contralateral femoral access was most frequently used (39.6%), and drug-coated balloons were the most common device strategy (63.7%). Technical success was achieved in 82.4% (95% CI 78.0-86.1). Access-site complications occurred in 5.7% (95% CI 3.6-8.7), in-hospital mortality was 2.9% (95% CI 1.6-5.4), and immediate hemodynamic success was 82.4% (95% CI 78.0-86.1). Landmark-based restenosis rates were 17.9%, 12.4%, and 24.7% at 30 days, 3 months, and 6 months, respectively.</p><p><strong>Conclusions: </strong>Endovascular revascularisation was feasible in this real-world Vietnamese PAD cohort, but restenosis remained frequent, supporting structured post-procedural surveillance.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"707-716"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148277176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Future cardiologyPub Date : 2026-07-01Epub Date: 2026-06-22DOI: 10.1080/14796678.2026.2686697
Akash Gopal, Prit Patel, Abdul Rasheed Bahar, George Kidess, Jawad Basit, M Chadi Alraies
{"title":"Impact of comorbid mental disorders on in‑hospital mortality and complications after ST‑segment elevation myocardial infarction.","authors":"Akash Gopal, Prit Patel, Abdul Rasheed Bahar, George Kidess, Jawad Basit, M Chadi Alraies","doi":"10.1080/14796678.2026.2686697","DOIUrl":"10.1080/14796678.2026.2686697","url":null,"abstract":"<p><strong>Background: </strong>Psychiatric comorbidities are common among patients with ST-segment elevation myocardial infarction (STEMI) and may be associated with in-hospital outcomes, which may differ among sexes.</p><p><strong>Methods: </strong>Using the National Inpatient Sample, an administrative claims database, we identified adults hospitalized with STEMI and psychiatric comorbidities and performed a retrospective cross-sectional observational study. Multivariable logistic regression and propensity-score matching were applied; outcomes were assessed between females and males with subgroup analyses for individual psychiatric conditions.</p><p><strong>Results: </strong>Of 145,830 patients, 45.51% were female. Female sex was associated with higher odds of in-hospital mortality (aOR 1.13, 95% CI: 1.01-1.26, <i>p</i> = 0.031) and pulmonary embolism (aOR 1.54, CI: 1.05-2.26, <i>p</i> = 0.027), and lower odds of cardiogenic shock (aOR 0.85, 95% CI: 0.79-0.92, <i>p</i> < 0.001). Female sex was also associated with lower odds of acute heart failure, acute kidney injury, cardiac arrhythmias, and device use (<i>p</i> < 0.05). Directional associations persisted after propensity-matching. Subgroup analyses corroborated trends and revealed female post-traumatic stress disorder patients demonstrated higher odds of in-hospital mortality (aOR 2.40, 95% CI 1.37-4.22, <i>p</i> = 0.002).</p><p><strong>Conclusion: </strong>Among patients with STEMI and psychiatric disorders, female sex was associated with higher odds of in-hospital mortality and lower odds of several adverse complications. Psychiatric comorbidities are heterogeneous, however, and findings vary.</p>","PeriodicalId":12589,"journal":{"name":"Future cardiology","volume":" ","pages":"695-705"},"PeriodicalIF":1.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148294275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}